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Cardiogenic shock: A serious heart attack complicationEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Cardiogenic shock — Comprehensive overview covers symptoms and treatment of this dangerous heart attack complication. Sponsored by:Chemotherapy.com - http://www.chemotherapy.com (Source: MayoClinic.com Full Feed)
Source: MayoClinic.com Full Feed - November 18, 2009 Category: Consumer Health News Source Type: news

Prognostic Factors for Pulmonary Embolism: The PREP Study, A Prospective Multicenter Cohort Study.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: BNP and echocardiography may be useful determinants of the short-term outcome for patients with PE, together with clinical findings. PE patients can be stratified according to the initial risk of adverse outcome, using a simple score based on clinical, echocardiographic and biochemical variables. PMID: 19910608 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - November 12, 2009 Category: Respiratory Medicine Authors: Sanchez O, Trinquart L, Caille V, Couturaud F, Pacouret G, Meneveau N, Verschuren F, Roy PM, Parent F, Righini M, Perrier A, Lorut C, Tardy B, Benoit MO, Chatellier G, Meyer G Tags: Am J Respir Crit Care Med Source Type: journals

Emergent coronary artery bypass grafting for cardiogenic shock caused by very late drug-eluting stent thrombosisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We describe a case of cardiogenic shock caused by a very late drug-eluting stent (DES) thrombosis. The patient underwent emergent coronary artery bypass grafting (CABG) and was discharged home 15 days after the operation. The incidence of stent restenosis had been reduced by the use of DES, but the Achilles’ heel of DES is represented by a higher rate of stent thrombosis. In our case, the DES thrombosis occurred 5 years after its implantation, underlining the importance of prolonged dual antiplatelet therapy. Even though rare, this complication may be life-threatening. We believe that CABG provides better event-free ...
Source: General Thoracic and Cardiovascular Surgery - November 11, 2009 Category: Cardiovascular & Thoracic Surgery Tags: General Thoracic and Cardiovascular Surgery Source Type: journals

Emergency Ultrasound Diagnosis of Cardiogenic Shock Due to Acute Mitral RegurgitationEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Academic Emergency Medicine)
Source: Academic Emergency Medicine - November 5, 2009 Category: Emergency Medicine Authors: Michael B. Stone Source Type: journals

Emergency Ultrasound Diagnosis of Cardiogenic Shock Due to Acute Mitral Regurgitation.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19891675 [PubMed - as supplied by publisher] (Source: Accident and Emergency Nursing)
Source: Accident and Emergency Nursing - November 5, 2009 Category: Emergency Medicine Authors: Stone MB Tags: Acad Emerg Med Source Type: journals

Severe cardiomyopathy following treatment with the tumour necrosis factor-{alpha} inhibitor adalimumab for Crohn's diseaseEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Adalimumab belongs to the group of tumour necrosis factor- inhibitors and has been approved for the treatment Crohn's Disease since 2007. Herein we report a severe adverse reaction to adalimumab in a 25-year-old female patient. One week after the initial-dose of adalimumab (160 mg), which was initiated due to an acute exacerbation of Crohn's disease, the patient developed a fulminant cardiomyopathy. In severe cardiogenic shock, the patient required an extracorporeal membrane-oxygenation system for 8 days until cardiac recovery. (Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - October 29, 2009 Category: Cardiology Authors: Emmert, M. Y., Salzberg, S. P., Emmert, L. S., Behjati, S., Plass, A., Felix, C., Falk, V., Gruenenfelder, J. Tags: CASE REPORT Source Type: journals

A three-group model to predict mortality in emergent coronary artery bypass graft surgery.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: Patients with an acute myocardial infarction and emergency aortocoronary CABG have an elevated operative risk. Logistic EuroSCORE overestimates the mortality rate. Three different risk groups can be defined, in which creatine kinase-MB/h-ratio and ST-segment elevation can more accurately predict operative risk. PMID: 19853087 [PubMed - in process] (Source: The Annals of Thoracic Surgery)
Source: The Annals of Thoracic Surgery - October 27, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Danner BC, Didilis VN, Stojanovic T, Popov A, Grossmann M, Seipelt R, Schöndube FA Tags: Ann Thorac Surg Source Type: journals

Role of a percutaneous ventricular assist device in decision making for a cardiac transplant program.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: The percTH was reliable, with no mechanical device failures and minimal associated adverse events. We support the use of the percTH in the BTD mode, allowing time for a more complete evaluation of neurologic and end-organ status without the added expense and morbidity of a long-term VAD. PMID: 19853093 [PubMed - in process] (Source: The Annals of Thoracic Surgery)
Source: The Annals of Thoracic Surgery - October 27, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Brinkman WT, Rosenthal JE, Eichhorn E, Dewey TM, Magee MJ, Savor DS, Riley AG, Prince SL, Worley CM, Herbert MA, Mack MJ Tags: Ann Thorac Surg Source Type: journals

Parallel Application of Extracorporeal Membrane Oxygenation and the CardioWest Total Artificial Heart as a Bridge to Transplant.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We describe a patient who was a heart transplant candidate with biventricular failure who underwent CardioWest total artificial heart-temporary (SynCardia Inc, Tucson, AZ) implantation with extracorporeal membrane oxygenation to manage the patient's subsequent respiratory failure. After respiratory and hemodynamic stabilization, the CardioWest total artificial heart-temporary served as a successful 62-day bridge-to-heart transplantation. PMID: 19853137 [PubMed - in process] (Source: The Annals of Thoracic Surgery)
Source: The Annals of Thoracic Surgery - October 27, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Anderson E, Jaroszewski D, Pierce C, Devaleria P, Arabia F Tags: Ann Thorac Surg Source Type: journals

Gender differences in patients with acute ST-elevation myocardial infarction complicated by cardiogenic shockEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion In women, STEMI was more often complicated by cardiogenic shock when compared to men. However, the use of early reperfusion therapy did not differ between the sexes. Primary PCI was associated with the best outcome in female patients with STEMI complicated by cardiogenic shock and is therefore the therapy of choice. Content Type Journal ArticleCategory Original PaperDOI 10.1007/s00392-009-0080-7Authors Oliver Koeth, Herzzentrum Ludwigshafen Department of Cardiology Ludwigshafen GermanyRalf Zahn, Herzzentrum Ludwigshafen Department of Cardiology Ludwigshafen GermanyTobias Heer, Herzzentrum L...
Source: Clinical Research in Cardiology - October 24, 2009 Category: Cardiology Tags: Clinical Research in Cardiology Source Type: journals

Contrast medium induced nephropathy in patients undergoing percutaneous coronary intervention for acute coronary syndrome: differences in STEMI and NSTEMIEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion This prospective study showed no differences in the incidence of developing CIN in patients undergoing PCI for STEMI or NSTEMI, but the predisposing factors, however, differed significantly. Although STEMI patients needed significantly more contrast medium for revascularisation, they did not develop CIN more often. CIN was associated with higher in-hospital complication rate and mortality. Thus, better preventive strategies according to the different predisposing factors leading to CIN are needed to reduce morbidity and mortality, especially in high risk patients. Content Type Journal Artic...
Source: Clinical Research in Cardiology - October 23, 2009 Category: Cardiology Tags: Clinical Research in Cardiology Source Type: journals

Parallel Application of Extracorporeal Membrane Oxygenation and the CardioWest Total Artificial Heart as a Bridge to Transplant [CASE REPORTS]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We describe a patient who was a heart transplant candidate with biventricular failure who underwent CardioWest total artificial heart-temporary (SynCardia Inc, Tucson, AZ) implantation with extracorporeal membrane oxygenation to manage the patient's subsequent respiratory failure. After respiratory and hemodynamic stabilization, the CardioWest total artificial heart-temporary served as a successful 62-day bridge-to-heart transplantation. (Source: The Annals of Thoracic Surgery)
Source: The Annals of Thoracic Surgery - October 22, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Anderson, E., Jaroszewski, D., Pierce, C., DeValeria, P., Arabia, F. Tags: Extracorporeal circulation, Mechanical Circulatory Assistance CASE REPORTS Source Type: journals

A Three-Group Model to Predict Mortality in Emergent Coronary Artery Bypass Graft Surgery [ORIGINAL ARTICLES: ADULT CARDIAC]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions Patients with an acute myocardial infarction and emergency aortocoronary CABG have an elevated operative risk. Logistic EuroSCORE overestimates the mortality rate. Three different risk groups can be defined, in which creatine kinase-MB/h-ratio and ST-segment elevation can more accurately predict operative risk. (Source: The Annals of Thoracic Surgery)
Source: The Annals of Thoracic Surgery - October 22, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Danner, B. C., Didilis, V. N., Stojanovic, T., Popov, A., Grossmann, M., Seipelt, R., Schondube, F. A. Tags: Coronary disease ORIGINAL ARTICLES: ADULT CARDIAC Source Type: journals

Role of a Percutaneous Ventricular Assist Device in Decision Making for a Cardiac Transplant Program [ORIGINAL ARTICLES: ADULT CARDIAC]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions The percTH was reliable, with no mechanical device failures and minimal associated adverse events. We support the use of the percTH in the BTD mode, allowing time for a more complete evaluation of neurologic and end-organ status without the added expense and morbidity of a long-term VAD. (Source: The Annals of Thoracic Surgery)
Source: The Annals of Thoracic Surgery - October 22, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Brinkman, W. T., Rosenthal, J. E., Eichhorn, E., Dewey, T. M., Magee, M. J., Savor, D. S., Riley, A. G., Prince, S. L., Worley, C. M., Herbert, M. A., Mack, M. J. Tags: Valve disease ORIGINAL ARTICLES: ADULT CARDIAC Source Type: journals

Postconditioning with levosimendan reduces the infarct size involving the PI3K pathway and KATP-channel activation but is independent of PDE-III inhibitionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In conclusion, levosimendan applied prior to reperfusion in acute myocardial infarction significantly reduces the infarct size in an in vivo rat model. This protection involves the PI3K pathway and the activation of mitochondrial KATP-channels, but is independent of PDE-III inhibition. This finding may open new possibilities for the treatment of patients with acute myocardial infarction using levosimendan, which is an already established therapy in cardiogenic shock. Whether the reduction of mortality in cardiogenic shock by levosimendan may in part be based on this postconditoning effect remains to be elucidated in c...
Source: Basic Research in Cardiology - October 20, 2009 Category: Cardiology Tags: Basic Research in Cardiology Source Type: journals

Benefit of Facilitated Percutaneous Coronary Intervention in High-Risk ST-Segment Elevation Myocardial Infarction Patients Presenting to Nonpercutaneous Coronary Intervention HospitalsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions Facilitation of PCI with a combination of abciximab and half-dose reteplase improved survival at 1 year in high-risk patients presenting to a spoke hospital with symptom-to-randomization time ≤4 h. Further prospective study of facilitated PCI in this subgroup of patients is warranted. (Source: Journal of the American College of Cardiology: Cardiovascular Interventions)
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - October 19, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Herrmann, H. C., Lu, J., Brodie, B. R., Armstrong, P. W., Montalescot, G., Betriu, A., Neuman, F.-J., Effron, M. B., Barnathan, E. S., Topol, E. J., Ellis, S. G., for the FINESSE Investigators Tags: Clinical Research Source Type: journals

Successful high-risk three vessel coronary intervention in a patient with cardiogenic shockEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report on a 59-year old man with acute myocardial infarction and profound cardiogenic shock in which the successful employment of the transcutaneous left ventricular assist device Impella 2.5 could rapidly establish temporary circulatory support in the catheterization laboratory, and thereby aid a high-risk three vessel revascularization procedure. Content Type Journal ArticleCategory KasuistikDOI 10.1007/s00390-009-0098-0Authors B. Borchert, Städtisches Klinikum Bielefeld Mitte Abteilung für Kardiologie und internistische Intensivmedizin Teutoburgerstr. 50 33604 Bielefeld DeutschlandT. Lawrenz, Städtisch...
Source: Intensivmedizin und Notfallmedizin - October 17, 2009 Category: Intensive Care Tags: Intensivmedizin und Notfallmedizin Source Type: journals

Defects in long chain fatty acid oxidation presenting as severe cardiomyopathy and cardiogenic shock in infancyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We present 2 cases of such disorders with cardiac manifestations during infancy, which responded well to a diet low in long chain fatty acids. (Source: Cardiology in the Young)
Source: Cardiology in the Young - October 14, 2009 Category: Cardiology Source Type: journals

Acute myocardial infarction and cardiogenic shock caused by a mobile thrombus in the ascending aorta unassociated with atherosclerosisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: European Heart Journal)
Source: European Heart Journal - October 14, 2009 Category: Cardiology Authors: Nakamori, S., Matsuoka, K., Kurita, T., Kusagawa, H., Katayama, Y. Tags: CARDIOVASCULAR FLASHLIGHTS Source Type: journals

A Rare type of Ventricular Oversensing in ICD Therapy—Inappropriate ICD Shock Delivery Due to Triple CountingEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Irregular sensing by triple counting of wide QRS complexes resulted in inappropriate shocks in a patient with a biventricular implantable cardioverter defibrillator (ICD): A 66-year-old male patient with ischemic cardiomyopathy, left bundle branch block, and impaired left ventricular function received a biventricular ICD for optimal therapy of heart failure (CHF). Two years after implantation, the patient experienced recurrent unexpected ICD shocks without clinical symptoms of malignant tachyarrhythmia, or worsened CHF. The patient's condition rapidly worsened, with progressive cardiogenic shock and electrical[ndash]mechan...
Source: Pacing and Clinical Electrophysiology : PACE - October 9, 2009 Category: Cardiology Authors: MICHAEL GUENTHER, THOMAS P. RAUWOLF, MANJA BOCK, RUTH H. STRASSER, MARTIN U. BRAUN Source Type: journals

Ductular Cholestasis, an Unusual Form of Intrahepatic Cholestasis, Associated With Cardiogenic Shock and Ventricular Assist DeviceEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report a case of ductular cholestasis, an unusual cholestatic hepatic failure with untractable coagulopathy, developed during the use of a magnetic levitation centrifugal pump, implanted as a bridge to heart transplantation, in a patient with cardiogenic shock (as an end-stage disease of idiopathic dilated cardiomyopathy). We discussed the pathophysiology of this entity and the possible related factors, including the assist device. Preemptive interventions have been advocated as the primary way of treatment. Preoperative optimization of heart function and avoidance of visceral hypoperfusion and sepsis may play a major r...
Source: Artificial Organs - October 9, 2009 Category: Transplant Surgery Authors: Alberto Mohedano-Gómez, José L. Pérez-Vela, Emilio Renes-Carreño, Carolina Ibarrola De-Andrés, María A. Corres-Peiretti, Primitivo Arribas-López, Julián Gutierrez-Rodriguez, Narciso Perales-Rodríguez-De-Viguri Source Type: journals

Clinical Benefit of Early Reperfusion Therapy in Patients With ST-Elevation Myocardial Infarction Usually Excluded from Randomized Clinical Trials (Results from the Maximal Individual Therapy in Acute Myocardial Infarction Plus [MITRA Plus] Registry)Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Randomized clinical trials (RCTs) usually enroll selected patient populations that may not be representative for patients seen in everyday practice. Therefore, concerns have been raised regarding their external validity. For the present study we evaluated the MITRA Plus registry and included 20,175 patients with ST-elevation myocardial infarction. We defined RCT-ineligible patients as patients fulfilling ≥1 of the following criteria: age ≥75 years, prehospital delay >12 hours, prehospital cardiopulmonary resuscitation, cardiogenic shock, impaired renal function, and previous stroke. Those patients (n = 9,369, 46.4%) we...
Source: The American Journal of Cardiology - October 5, 2009 Category: Cardiology Authors: Oliver Koeth, Ralf Zahn, Anselm Kai Gitt, Timm Bauer, Claus Juenger, Jochen Senges, Uwe Zeymer, Maximal Individual Therapy in Acute Myocardial Infarction Plus (MITRA Plus) Study Group Tags: Coronary Artery Disease Source Type: journals

Hemodynamic variables and mortality in cardiogenic shock: a retrospective cohort studyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
IntroductionDespite the key role of hemodynamic goals, there are few data addressing the question as to which hemodynamic variables are associated with outcome or should be targeted in cardiogenic shock patients. The aim of this study was to investigate the association between hemodynamic variables and cardiogenic shock mortality. Methods: Medical records and the patient data management system of a multidisciplinary intensive care unit (ICU) were reviewed for patients admitted because of cardiogenic shock. In all patients, the hourly variable time integral of hemodynamic variables during the first 24 hours after ICU admiss...
Source: Critical Care - October 1, 2009 Category: Intensive Care Authors: Christian TorgersenChristian SchmittingerSarah WagnerHanno UlmerJukka TakalaStephan JakobMartin Dunser Source Type: journals

Unprotected left main revascularization in patients with acute coronary syndromesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion Unprotected left main coronary disease in ACS is associated with high mortality, especially in patients with STEMI and/or haemodynamic or arrhythmic instability. Percutaneous coronary intervention is now the most common revascularization strategy and preferred in higher risk patients. Coronary artery bypass graft is often delayed and performed in lower risk patients, leading to good 6-month survival. The two approaches therefore appear complementary. (Source: European Heart Journal)
Source: European Heart Journal - October 1, 2009 Category: Cardiology Authors: Montalescot, G., Brieger, D., Eagle, K. A., Anderson, F. A., FitzGerald, G., Lee, M. S., Steg, Ph. G., Avezum, A., Goodman, S. G., Gore, J. M., for the GRACE Investigators Tags: ESC hot line Source Type: journals

Outcomes in patients with intra-aortic balloon pump who met the same inclusion criteria in the PROTECT II (a prospective feasibility trial investigating the use of the impella recover LP 2.5 system in patients undergoing high risk percutaneous coronary intervention) StudyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The Impella Recover LP 2.5 device is a mechanical circulatory device used during cardiac surgery, cardiogenic shock (CS), and acute myocardial infarction (AMI), and is being evaluated in the PROTECT II study for high-risk percutaneous coronary intervention (PCI) compared to intra-aortic balloon pump (IABP). The aim of our study was to assess a real-world event rate in patients with prophylactic IABP usage during high-risk PCI and to assess whether the PROTECT II study could show a beneficial effect of the Impella device. (Source: Cardiovascular Revascularization Medicine)
Source: Cardiovascular Revascularization Medicine - September 30, 2009 Category: Cardiology Authors: Asmir I. Syed, Amit Kakkar, Yanlin Li, Sara D. Collins, Itsik Ben-Dor, Gabriel Manuela, Gilles Lemesle, Mickey Scheinowitz, Rebecca Torguson, Kimberly Kaneshige, Zhenyi Xue, Joseph Lindsay, Kenneth M. Kent, Lowell F. Satler, William O. Suddath, Augusto D. Tags: Special Feature Source Type: journals

[Diffuse arterial calcified elastopathy. A case report.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report a case of diffuse arterial calcified elastopathy discovered in a neonatal intensive care unit, during management of a cardiogenic shock in a 3-months old infant. This observation demonstrates the importance of systematic measurement of the arterial tension, family screening and the impact of the ultrasound in the detection of vascular calcifications. Treatment remains essentially symptomatic. PMID: 19800770 [PubMed - as supplied by publisher] (Source: Archives de Pediatrie)
Source: Archives de Pediatrie - September 30, 2009 Category: Pediatrics Authors: Zakaria A, Kabiri M, Kabbaj M, Barkat A, Lamdouar Bouazzaoui N Tags: Arch Pediatr Source Type: journals

BCIS-1 Trial: "Bailout" Intra-Aortic Balloon Pump Beats Elective Use in Low EF/High-Risk PatientsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The study provides an important answer to a question that has divided some interventionalists. Those who "swear" by IABP use for all high-risk, low-EF patients should rethink their practice. In hypotensive patients and those with cardiogenic shock, IABPs play a key role. Heartwire (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - September 30, 2009 Category: Consumer Health News Tags: Cardiology Source Type: news

Anti-thymocyte Globulin as an Adjunct to Treatment of Fulminant Lymphocytic MyocarditisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In this study we add our experience with anti-thymocyte globulin as an adjunct to standard medical therapy for 5 patients presenting with cardiogenic shock due to fulminant myocarditis. All cases were associated with rapid and dramatic improvement in hemodynamic and electrophysiologic abnormalities, returning patients to NYHA Class I and cardiac function to normal or near normal by discharge. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - September 27, 2009 Category: Transplant Surgery Authors: Vance Manins, Niki Parle, Lorry Dembo, Gerry O'Driscoll Tags: Clinical Dilemmas Source Type: journals

Predictors of 30-day mortality in patients with refractory cardiogenic shock following acute myocardial infarction despite a patent infarct arteryEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: The SBP, creatinine clearance, and number of vasopressors are significant predictors of mortality in patients with persistent vasopressor-dependent cardiogenic shock following acute MI despite a patent infarct artery. These prognostic variables may be useful for risk-stratification and in selecting patients for investigation of additional therapies. (Source: American Heart Journal)
Source: American Heart Journal - September 24, 2009 Category: Cardiology Authors: Jason N. Katz, Amanda L. Stebbins, John H. Alexander, Harmony R. Reynolds, Karen S. Pieper, Witold Ruzyllo, Karl Werdan, Alexander Geppert, Vladimir Dzavik, Frans Van de Werf, Judith S. Hochman, for the TRIUMPH Investigators Tags: Acute Ischemic Heart Disease Source Type: journals

Characterization and outcomes of women and men with non–ST-segment elevation myocardial infarction and nonobstructive coronary artery disease: Results from the Can Rapid Risk Stratification of Unstable Angina Patients Suppress Adverse Outcomes with Early Implementation of the ACC/AHA Guidelines (CRUSADE) Quality Improvement InitiativeEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Among NSTE ACS patients undergoing coronary angiography, absence of obstructive CAD is more common in women than men. Although nonobstructive CAD was twice as common among women with NSTEMI, sex differences in characteristics and outcomes were similar to those found with obstructive CAD. Unadjusted in-hospital outcomes of NSTEMI patients with nonobstructive CAD are favorable in both sexes. Whether the underlying pathophysiology of NSTE ACS without documentation of obstructive CAD is different between women and men requires further study. (Source: American Heart Journal)
Source: American Heart Journal - September 24, 2009 Category: Cardiology Authors: Erika R. Gehrie, Harmony R. Reynolds, Anita Y. Chen, Brian H. Neelon, Matthew T. Roe, W. Brian Gibler, E. Magnus Ohman, L. Kristin Newby, Eric D. Peterson, Judith S. Hochman Tags: Acute Ischemic Heart Disease Source Type: journals

A Long-term Follow-up of a Girl with Dilated Cardiomyopathy after Mitral Valve Replacement and Septal Anterior Ventricular Exclusion.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We treated a 10 year 11 month old girl with severe mitral valve regurgitation, stenosis and dilated cardiomyopathy, presented with New York Heart Association (NYHA) functional classification IV. She acutely developed cardiogenic shock with a dyskinetic anterior-septal left ventricle and entered a shock state during our consultation about heart transplantation. Septal-anterior ventricular exclusion and mitral valve replacement were performed emergently. She successfully recovered from cardiogenic shock. Left ventricular end-diastolic diameter and fractional shortening improved from 71.5mm (188.0% of normal) to 62.5mm (144.2...
Source: Journal of Cardiothoracic Surgery - September 22, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Shiro BabaHiraku DoiTadashi IkedaMasashi KomedaTatsutoshi Nakahata Source Type: journals

Impact of Admission Glucose Level and Presence of Diabetes Mellitus on Mortality in Patients with Non-ST-Segment Elevation Acute Coronary Syndrome Treated Conservatively: Dziewierz A, Giszterowicz D, Siudak Z, et al. Am J Cardiol 2009;103:954–8Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This study out of Poland utilized the Krakow registry of acute coronary syndromes, a prospective, multi-center, observational registry designed to examine epidemiology, in-hospital management, and outcomes of patients with acute coronary syndrome (ACS) in Krakow, Poland, to assess the impact of admission glucose level on the mortality of patients with non-ST-segment elevation ACS. The study includes 763 patients with admission glucose data and non-ST-segment elevation ACS. These patients were stratified into five groups based on blood glucose concentration: 24.2% had admission glucose levels of < 5 mmol/L (90 mg/dL), 50.6%...
Source: The Journal of Emergency Medicine - September 22, 2009 Category: Emergency Medicine Authors: Ryan Paterson Tags: Abstracts Source Type: journals

The use of extracorporeal membrane oxygenation in patients with therapy refractory cardiogenic shock as a bridge to implantable left ventricular assist device and perioperative right heart supportEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We present our experience using extracorporeal membrane oxygenation (ECMO) in patients with cardiogenic shock to stabilized organ function prior to LVAD implantation. Between September 2006 and March 2008, five patients in cardiogenic shock with preexisting organ dysfunction (impaired liver and kidney function) were supported with ECMO before LVAD implantation. ECMO-LVAD interval was 8 ± 4 days. All patients were transferred to a LVAD. At the LVAD implantation time, glutamic-oxaloacetic transaminase (GOT) decreased from 206.25 ± 106.93 Ul −1 to 70.6 ± 32.9 U l−1, glutamic-pyruvic transaminase (GPT) decreased fro...
Source: Journal of Artificial Organs - September 18, 2009 Category: Transplant Surgery Tags: Journal of Artificial Organs Source Type: journals

Percutaneous left ventricular assist devices during cardiogenic shock and high-risk percutaneous coronary interventionsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This article reviews the growing evidence supporting the clinical use of left ventricular assist devices. Specifically, we discuss the use of left ventricular assist devices in patients with cardiogenic shock, in patients with acute ST-elevation myocardial infarction without shock, and during high-risk percutaneous coronary interventions. Content Type Journal ArticleDOI 10.1007/s11886-009-0051-7Authors Stéphane CookStephan Windecker, University Hospital Bern Department of Cardiology 3010 Bern Switzerland Journal Current Cardiology ReportsOnline ISSN 1534-3170Print ISSN 1523-3782 Journal Volume Volume 11...
Source: Current Cardiology Reports - September 16, 2009 Category: Cardiology Tags: Current Cardiology Reports Source Type: journals

Acute myocarditis in children: Current concepts and managementEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Opinion statement The spectrum of presentation of pediatric myocarditis ranges from minor flu-like illness with chest pain to acute cardiogenic shock in a previously healthy child. A major change in the diagnostic evaluation of myocarditis is a shift in focus away from endomyocardial biopsy and histologic confirmation toward cardiac MRI for noninvasive diagnosis and prognostication of acute myocarditis. Cardiac MRI may be particularly useful in pediatric patients, considering the risks associated with biopsy in children. Some of the MRI characteristics seen in pediatric patients with acute myocarditis also m...
Source: Current Treatment Options in Cardiovascular Medicine - September 16, 2009 Category: Cardiology Tags: Current Treatment Options in Cardiovascular Medicine Source Type: journals

[Acute non protected main left coronary artery occlusion: A report of six cases treated by angioplasty.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: We demonstrate the feasibility of percutaneous coronary intervention of acute main left coronary occlusion. Inspite successful procedure, intrahospital mortality rate is still high and prognosis is related to cardiogenic shock. PMID: 19793577 [PubMed - as supplied by publisher] (Source: Annales de Cardiologie et d'Angeiologie)
Source: Annales de Cardiologie et d'Angeiologie - September 14, 2009 Category: Cardiology Authors: Ghrissi I, Nallet O, Amara W, Michaud P, Estève JB, Cattan S Tags: Ann Cardiol Angeiol (Paris) Source Type: journals

[Original articles] Primary percutaneous coronary intervention for acute ST-segment elevation myocardial infarction: changing patterns of vascular access, radial versus femoral arteryEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: In the setting of acute ST-elevation myocardial infarction without cardiogenic shock, transradial primary angioplasty is safe, with comparable outcomes to a femoral approach and a lower risk of vascular complications. (Source: Heart)
Source: Heart - September 13, 2009 Category: Cardiology Authors: Hetherington, S L, Adam, Z, Morley, R, de Belder, M A, Hall, J A, Muir, D F, Sutton, A G C, Swanson, N, Wright, R A Tags: Acute coronary syndromes, Drugs: cardiovascular system, Interventional cardiology, Acute coronary syndromes, Percutaneous intervention, Clinical diagnostic tests, Epidemiology Original articles Source Type: journals

Cardiogenic Shock from Left Ventricular Dysfunction Complicating an Acute ST-elevation Myocardial Infarction.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This article discusses the SHOCK trial and potential mechanisms of benefit from revascularization as well as more recent information. Adjunctive therapies have been disappointing. To further improve outcomes, earlier pre-emptive and preventive strategies to ensure early revascularization should be pursued. PMID: 19742431 [PubMed - in process] (Source: The American Heart Hospital Journal)
Source: The American Heart Hospital Journal - September 11, 2009 Category: Cardiology Authors: White HD, Wong CK, Tags: Am Heart Hosp J Source Type: journals

Survival benefit of LV assist devices in cardiogenic shock questionedEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Left ventricular assist devices improve hemodynamic profile in patients with cardiogenic shock, but provide no extra survival benefit over intra-aortic balloon pumps, results of a meta-analysis demonstrate. (Source: MedWire News - Cardiology)
Source: MedWire News - Cardiology - September 6, 2009 Category: Cardiology Source Type: news

Massive Pulmonary Embolism: Percutaneous Emergency Treatment Using an Aspirex Thrombectomy CatheterEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract Massive pulmonary embolism (PE) is a life-threatening condition with a high early mortality rate caused by acute right ventricular failure and cardiogenic shock. A 51-year-old woman with a massive PE and contraindication for thrombolytic therapy was treated with percutaneous mechanical thrombectomy using an Aspirex 11F catheter (Straub Medical AG, Wangs, Switzerland). The procedure was successfully performed and showed a good immediate angiographic result. The patient made a full recovery from the acute episode and was discharged on heparin treatment. Our case report indicates that in patients with ...
Source: CardioVascular and Interventional Radiology - September 3, 2009 Category: Radiology Tags: CardioVascular and Interventional Radiology Source Type: journals

PRAGUE-7 Cardiac Study ResultsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The outcome of patients with acute myocardial infarction (AMI) complicated by cardiogenic shock* is generally very poor. Although early mechanical revascularisation by primary PCI has been shown as superior to medical treatment, the mortality range remains high (at about 45-60%). (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - September 1, 2009 Category: Consumer Health News Tags: Cardiovascular / Cardiology Source Type: news

Evaluating percutaneous support for cardiogenic shock: data shock and sticker shockEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: European Heart Journal)
Source: European Heart Journal - August 31, 2009 Category: Cardiology Authors: Desai, N. R., Bhatt, D. L. Tags: EDITORIALS Source Type: journals

Percutaneous left ventricular assist devices vs. intra-aortic balloon pump counterpulsation for treatment of cardiogenic shock: a meta-analysis of controlled trialsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion Although percutaneous LVAD provides superior haemodynamic support in patients with cardiogenic shock compared with IABP, the use of these more powerful devices did not improve early survival. These results do not yet support percutaneous LVAD as first-choice approach in the mechanical management of cardiogenic shock. (Source: European Heart Journal)
Source: European Heart Journal - August 31, 2009 Category: Cardiology Authors: Cheng, J. M., den Uil, C. A., Hoeks, S. E., van der Ent, M., Jewbali, L. S.D., van Domburg, R. T., Serruys, P. W. Tags: Coronary heart disease Source Type: journals

Clinical outcomes in a community-based single operator coronary interventional program.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: A low-volume coronary interventional program can achieve angiographic percutaneous coronary interventional success rates and major adverse cardiac events and the need for target lesion revascularization comparable to those in high-volume major cardiac referral centers. These results were obtained even when high-risk patients with ST-elevation myocardial infarction were not excluded from the analysis. PMID: 19813499 [PubMed - in process] (Source: WMJ)
Source: WMJ - August 31, 2009 Category: Journals (General) Authors: Posner CJ, Kaufman CL Tags: WMJ Source Type: journals

GP IIb/IIIa Inhibitor of No Benefit in AMI Patients With Cardiogenic ShockEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Seriously ill patients with acute MI complicated by cardiogenic shock did not benefit from the routine use of abciximab during primary PCI, results of the PRAGUE-7 study show. Heartwire (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - August 31, 2009 Category: Consumer Health News Tags: Cardiology Source Type: news

GP IIb/IIIa inhibitor of no benefit in AMI patients with cardiogenic shockEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Seriously ill patients with acute MI complicated by cardiogenic shock did not benefit from the routine use of abciximab during primary PCI, results of the PRAGUE-7 study show. (Source: theHeart.org)
Source: theHeart.org - August 31, 2009 Category: Cardiology Source Type: info

Clinical Experience Using the Levitronix CentriMag System for Temporary Right Ventricular Mechanical Circulatory SupportEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: The CentriMag system provides effective temporary mechanical circulatory support for RV failure. Ease of implantation and a high rate of successful device weaning justify the use of the CentriMag system for temporary RV support. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - August 31, 2009 Category: Transplant Surgery Authors: Jay K. Bhama, Robert L. Kormos, Yoshiya Toyoda, Jeffrey J. Teuteberg, Kenneth R. McCurry, Michael P. Siegenthaler Tags: Clinical Dilemmas and Innovation Source Type: journals

Mechanical Circulatory Support Devices Improve Tissue Perfusion in Patients With End-Stage Heart Failure or Cardiogenic ShockEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: Mechanical circulatory support for severe heart failure is associated with a consistent, significant, and sustained improvement in tissue perfusion, as measured at the bedside by a 2-dimensional microcirculation imaging technique. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - August 31, 2009 Category: Transplant Surgery Authors: Corstiaan A. den Uil, Alexander P. Maat, Wim K. Lagrand, Martin van der Ent, Lucia S.D. Jewbali, Robert J. van Thiel, Peter E. Spronk, Maarten L. Simoons Tags: Original Clinical Science Source Type: journals

Results from the PRAGUE-7 studyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(European Society of Cardiology) The outcome of patients with acute myocardial infarction (AMI) complicated by cardiogenic shock is generally very poor. Although early mechanical revascularization by primary PCI has been shown as superior to medical treatment, the mortality range remains high (at about 45-60 percent). (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 31, 2009 Category: Global & Universal Source Type: news

Short- and Long-Term Survival of Patients Transferred to a Tertiary Care Center on Temporary Extracorporeal Circulatory Support [ORIGINAL ARTICLES: ADULT CARDIAC]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions Nearly half of all patients transferred on temporary extracorporeal MCS survive to discharge. Most of the long-term survivors received a heart transplant. Age and renal function were independent predictors of death, suggesting that survival is maximized by considering eligibility for cardiac transplantation. (Source: The Annals of Thoracic Surgery)
Source: The Annals of Thoracic Surgery - August 30, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Haft, J. W., Pagani, F. D., Romano, M. A., Leventhal, C. L., Dyke, D. B., Matthews, J. C. Tags: Mechanical Circulatory Assistance ORIGINAL ARTICLES: ADULT CARDIAC Source Type: journals