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Cangrelor not CHAMPION for PCI patientsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Two CHAMPION trials show disappointing results for the novel fast-acting intravenous platelet inhibitor cangrelor before or after percutaneous coronary intervention, with no reduction in the rate of death, myocardial infarction, or revascularization at 48 hours compared with clopidogrel treatment. (Source: MedWire News - Thrombosis)
Source: MedWire News - Thrombosis - November 20, 2009 Category: Internal Medicine Source Type: news

Transfusion Tied to Mortality in STEMI Treated With Primary PCIEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Red blood cell transfusion is associated with increased mortality in patients with ST-segment elevation myocardial infarction (STEMI) treated with primary percutaneous coronary intervention (PCI), researchers report in the European Heart Journal for November. Reuters Health Information (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - November 19, 2009 Category: Consumer Health News Tags: Cardiology Source Type: news

Journal Scan: 2009 Focused Updates: ACC/AHA Guidelines for the Management of Patients With ST-Elevation Myocardial Infarction (Updating the 2004 Guideline and 2007 Focused Update) and ACC/AHA/SCAI Guidelines on Percutaneous Coronary Intervention (Updating the 2005 Guideline and 2007 Focused Update) (J Am Coll Cardiol 2009;Nov 18:[Epub ahead of print].)Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Cardiosource)
Source: Cardiosource - November 19, 2009 Category: Cardiology Source Type: organizations

2009 Focused Updates: ACC/AHA Guidelines for the Management of Patients With ST-Elevation Myocardial Infarction (Updating the 2004 Guideline and 2007 Focused Update) and ACC/AHA/SCAI Guidelines on Percutaneous Coronary Intervention (Updating the 2005 Guideline and 2007 Focused Update)Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
No abstract (Source: Catheterization and Cardiovascular Interventions)
Source: Catheterization and Cardiovascular Interventions - November 19, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Frederick G. Kushner, Mary Hand, Sidney C. Smith Jr, Spencer B. King III, Jeffrey L. Anderson, Elliott M. Antman, Steven R. Bailey, Eric R. Bates, James C. Blankenship, Donald E. Casey Jr, Lee A. Green, Alice K. Jacobs, Judith S. Hochman, Harlan M. Krumho Source Type: journals

Initial medical rather than interventional management more cost-effective for most diabetic patients with stable CHDEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Source: Circulation Area: News The most cost-effective initial treatment for diabetic patients with stable coronary heart disease (CHD) depends on the seriousness of their CHD: intensive medical management appears more cost-effective than percutaneous coronary intervention (PCI) in less seriously affected patients, however those with more severe disease should probably proceed straight to CABG (coronary artery bypass grafting).   These conclusions come from pre-specified secondary outcome and economic analyses of the BARI-2D trial (Bypass Angioplasty Revascularization Investigation 2 Diabetes), published early on...
Source: NeLM - Cardiovascular Medicine - November 19, 2009 Category: Cardiology Source Type: organizations

Focused update 2009 of ACC/AHA guidelines for management of ST-elevation myocardial infarction and percutaneous coronary interventionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Source: Circulation Area: News In an effort to respond promptly to new evidence, the American College of Cardiology Foundation/American Heart Association (ACCF/AHA) Task Force on Practice Guidelines has created a "focused update" process to revise the existing guideline recommendations that are affected by evolving data or opinion. These updated guideline recommendations reflect a consensus of expert opinion after a review primarily of late-breaking clinical trials identified as being important to the relevant patient population, as well as a review of other new data deemed to have an impact on patient care. A focused upd...
Source: NeLM - Cardiovascular Medicine - November 19, 2009 Category: Cardiology Source Type: organizations

New Updates to AHA/ACC/SCAI Clinical Guidelines Recommend Treatment with Effient(R) for Patients with Acute Coronary Syndromes Managed with PCIEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PARSIPPANY, N.J. and INDIANAPOLIS, Nov. 18 (HSMN NewsFeed) -- Effient® (prasugrel) tablets, a new antiplatelet medicine, was added as a treatment option in two clinical guideline updates: one for patients receiving percutaneous coronary intervention ... Biopharmaceuticals, CardiologyEli Lilly, Effient, prasugrel, antiplatelet, STEMI (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - November 18, 2009 Category: Pharmaceuticals Source Type: news

AHA: Prasugrel Incorporated into New STEMI Guidelines (CME/CE)Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
ORLANDO (MedPage Today) -- A 60-milligram loading dose of prasugrel (Effient) is now a recommended alternative to clopidogrel for patients with ST-elevation myocardial infarction (STEMI) who undergo primary percutaneous coronary intervention, according to updated guidelines. (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - November 18, 2009 Category: Cardiology Source Type: news

An unusual primary percutaneous coronary interventionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Heart)
Source: Heart - November 18, 2009 Category: Cardiology Authors: Ezzat, V A, Holdright, D R Tags: Miscellanea Source Type: journals

Prognostic value of coronary revascularisation-related myocardial injury: a cardiac magnetic resonance imaging studyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Myocardial injury during PCI or CABG, identified by DE-CMR, adversely affects clinical outcome. This suggests the benefits from revascularisation could partially be offset by new myocardial injury caused by the intervention itself. (Source: Heart)
Source: Heart - November 18, 2009 Category: Cardiology Authors: Rahimi, K, Banning, A P, Cheng, A S H, Pegg, T J, Karamitsos, T D, Channon, K M, Darby, S, Taggart, D P, Neubauer, S, Selvanayagam, J B Tags: Editor's choice, Drugs: cardiovascular system, Interventional cardiology, Acute coronary syndromes, Percutaneous intervention, Clinical diagnostic tests Original articles Source Type: journals

AHA: Beating Heart Bypass Better for Brain than PCI (CME/CE)Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
ORLANDO (MedPage Today) -- Percutaneous coronary intervention (PCI) may be worse for the brain than coronary artery bypass grafting (CABG) without the heart-lung machine, researchers reported here. (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - November 18, 2009 Category: Cardiology Source Type: news

The relationship between reverse redistribution of 99mTc-tetrofosmin in sub-acute phase and left ventricular functional recovery in chronic phase in patients with acute myocardial infarctionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion  These findings suggested that quantitative evaluation of RRD by gated 99mTc-tetrofosmin SPECT in the sub-acute phase can predict recovery of left ventricular function in the chronic phase with higher accuracy in patients with AMI who underwent direct PCI. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s12149-009-0318-5Authors Sei Fujiwara, Kobe University Graduate School of Medicine Division of Cardiovascular Medicine, Department of Internal Medicine 7-5-1 Kusunoki-cho, Chuo-ku Kobe Hyogo 650-0017 JapanHideyuki Shiotani, Kobe University Graduate School of Health Sciences Ko...
Source: Annals of Nuclear Medicine - November 17, 2009 Category: Radiology Tags: Annals of Nuclear Medicine Source Type: journals

Effects of Depressive Symptoms, Anxiety and Alexithymia on Physical Functioning 6 Months after Percutaneous Transluminal Coronary AngioplastyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Psychother Psychosom 2010;79:59-60 (DOI:10.1159/000259420) (Source: Karger Publishers)
Source: Karger Publishers - November 17, 2009 Category: Cancer & Oncology Source Type: journals

Stroke Incidence Related To Angioplasty Remains Steady Over Past 15 YearsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Results of a Mayo Clinic study show the incidence of stroke or mini-stroke related to a coronary angioplasty remained steady over a 15-year period. Researchers say this is good news because physicians now are performing the artery-opening procedure on older patients who are sicker and need more complicated treatment. VIDEO ALERT: Additional audio and video resources, including comments by Dr. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 17, 2009 Category: Consumer Health News Tags: Stroke Source Type: news

Stroke Incidence Related To Angioplasty Remains Steady Over Past 15 YearsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Results of a Mayo Clinic study show the incidence of stroke or mini-stroke related to a coronary angioplasty remained steady over a 15-year period. Researchers say this is good news because physicians now are performing the artery-opening procedure on older patients who are sicker and need more complicated treatment. (Source: Stroke / Neuroprotection News From Medical News Today)
Source: Stroke / Neuroprotection News From Medical News Today - November 17, 2009 Category: Neurology Tags: Stroke Source Type: news

Ticagrelor shows better efficacy compared to clopidogrel in patients with STEMI and planned PCIEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Source: Reuters Health News Area: News According to research presented at the American Heart Association Scientific Session, ticagrelor prevents cardiovascular (CV) events in very high risk patients (those with ST Segment Elevated Myocardial Infarction (STEMI) who require percutaneous coronary intervention (PCI)) with no increased risk of overall major bleeding compared to the current standard of treatment, clopidogrel.   Researchers presented the results of the phase III PLATelet inhibition and patient Outcomes (PLATO study) which showed that compared to clopidogrel, treatment with ticagrelor resulted in a reduc...
Source: NeLM - Cardiovascular Medicine - November 17, 2009 Category: Cardiology Source Type: organizations

AHA: Proton Pump Inhibitors May Up Post-PCI MortalityEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In patients who undergo percutaneous coronary intervention with drug-eluting stents, use of proton pump inhibitors is associated with an increased risk of all-cause mortality, according to research presented this week at the American Heart Association Scientific Sessions, held from Nov. 14 to 18 in Orlando, Fla. (Source: Modern Medicine)
Source: Modern Medicine - November 17, 2009 Category: Journals (General) Source Type: info

AHA: Two Separate Studies Find Cangrelor Not SuperiorEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In patients undergoing percutaneous coronary intervention, the use of cangrelor is not superior to the use of clopidogrel or placebo, according to two studies published online Nov. 15 in the New England Journal of Medicine to coincide with the American Heart Association Scientific Sessions, held from Nov. 14 to 18 in Orlando, Fla. (Source: Modern Medicine)
Source: Modern Medicine - November 17, 2009 Category: Journals (General) Source Type: info

AHA: PCI Without Surgical Backup Appears Safe (CME/CE)Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
ORLANDO (MedPage Today) -- Patients with ST-elevation myocardial infarction (STEMI) appear to have similar outcomes regardless of whether they undergo a first percutaneous coronary intervention at a center with onsite surgical backup or not, researchers found. (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - November 16, 2009 Category: Cardiology Source Type: news

Mechanism and Predictors of Failed Transradial Approach for Percutaneous Coronary InterventionsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions Transradial approach PCI can be performed by low-to-intermediate volume operators with standard equipment with a low failure rate. Age >75 years, prior coronary artery bypass graft surgery, and short stature are independent predictors of TR-PCI failure. Appropriate patient selection and careful risk assessment are needed to maximize benefits offered by TR-PCI. (Source: Journal of the American College of Cardiology: Cardiovascular Interventions)
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - November 16, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Dehghani, P., Mohammad, A., Bajaj, R., Hong, T., Suen, C. M., Sharieff, W., Chisholm, R. J., Kutryk, M. J.B., Fam, N. P., Cheema, A. N. Tags: Mini-Focus Issue: Transradial Approach Source Type: journals

Prognostic Impact of Periprocedural Bleeding and Myocardial Infarction After Percutaneous Coronary Intervention in Unselected Patients: Results From the EVENT (Evaluation of Drug-Eluting Stents and Ischemic Events) RegistryEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions Among unselected PCI patients, both post-PCI bleeding and pMI are independently associated with increased 1-year mortality. Continued efforts to reduce these complications after PCI are warranted. (Source: Journal of the American College of Cardiology: Cardiovascular Interventions)
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - November 16, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Lindsey, J. B., Marso, S. P., Pencina, M., Stolker, J. M., Kennedy, K. F., Rihal, C., Barsness, G., Piana, R. N., Goldberg, S. L., Cutlip, D. E., Kleiman, N. S., Cohen, D. J., on behalf of the EVENT Registry Investigators Tags: Clinical Research Source Type: journals

Enoxaparin Versus Unfractionated Heparin in Elective Percutaneous Coronary Intervention: 1-Year Results From the STEEPLE (SafeTy and Efficacy of Enoxaparin in Percutaneous coronary intervention patients, an internationaL randomized Evaluation) TrialEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions The 1-year mortality rates were low and comparable between patients receiving enoxaparin and UFH during elective PCI. Periprocedural ischemic or bleeding events were the strongest independent predictors of 1-year mortality. (The STEEPLE Trial; NCT00077844) (Source: Journal of the American College of Cardiology: Cardiovascular Interventions)
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - November 16, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Montalescot, G., Gallo, R., White, H. D., Cohen, M., Steg, Ph. G., Aylward, P. E.G., Bode, C., Chiariello, M., King, S. B., Harrington, R. A., Desmet, W. J., Macaya, C., Steinhubl, S. R., for the STEEPLE Investigators Tags: Clinical Research Source Type: journals

Antithrombin Therapy for Elective Percutaneous Coronary Intervention: Which Agent to Use? Does It Matter?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Journal of the American College of Cardiology: Cardiovascular Interventions)
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - November 16, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Brener, S. J. Tags: Editorial Comment Source Type: journals

The Worry About Clopidogrel "Nonresponsiveness": Identification and Treatment in the Post-Percutaneous Coronary Intervention PatientEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Journal of the American College of Cardiology: Cardiovascular Interventions)
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - November 16, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Gurbel, P. A., Tantry, U. S., Shuldiner, A. R. Tags: Editorial Comment Source Type: journals

Evaluation of the Effect of a Concurrent Chronic Total Occlusion on Long-Term Mortality and Left Ventricular Function in Patients After Primary Percutaneous Coronary InterventionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions The presence of a CTO and not MVD alone is associated with long-term mortality even when early deaths are excluded from analysis. The presence of a CTO is associated with reduced LVEF and further deterioration of LVEF. (Source: Journal of the American College of Cardiology: Cardiovascular Interventions)
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - November 16, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Claessen, B. E.P.M., van der Schaaf, R. J., Verouden, N. J., Stegenga, N. K., Engstrom, A. E., Sjauw, K. D., Kikkert, W. J., Vis, M. M., Baan, J., Koch, K. T., de Winter, R. J., Tijssen, J. G.P., Piek, J. J., Henriques, J. P.S. Tags: Clinical Research Source Type: journals

No Association of Chromosome 9p21.3 Variation With Clinical and Angiographic Outcomes After Placement of Drug-Eluting StentsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions Specific polymorphisms in the chromosome 9p21.3 region that were shown to be associated with coronary heart disease in genomewide analyses were not related to the clinical and angiographic outcomes after the placement of drug-eluting stents in coronary arteries. (Source: Journal of the American College of Cardiology: Cardiovascular Interventions)
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - November 16, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Hoppmann, P., Erl, A., Turk, S., Tiroch, K., Mehilli, J., Schomig, A., Kastrati, A., Koch, W. Tags: Clinical Research Source Type: journals

Successful Coronary Angioplasty Via the Radial Approach After Sealing a Radial PerforationEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Journal of the American College of Cardiology: Cardiovascular Interventions)
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - November 16, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Rigatelli, G., Dell'Avvocata, F., Ronco, F., Doganov, A. Tags: Images in Intervention Source Type: journals

PLATO: Ticagrelor benefits seen in STEMI subanalysisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The investigational oral antiplatelet therapy ticagrelor significantly reduces the risk for major cardiovascular events and all-cause mortality compared with clopidogrel in patients with ST-segment elevation myocardial infarction and planned primary percutaneous coronary intervention, a predefined subanalysis of the PLATO trial shows. (Source: MedWire News - Thrombosis)
Source: MedWire News - Thrombosis - November 16, 2009 Category: Internal Medicine Source Type: news

Mayo Study Shows Stroke Incidence Related to Angioplasty Remains Steady over Past 15 YearsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Results of a Mayo Clinic study show the incidence of stroke or mini-stroke related to a coronary angioplasty remained steady over a 15-year period. (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - November 16, 2009 Category: Research Authors: Mayo Clinic Source Type: organizations

Mayo Study Shows Stroke Incidence Related to Angioplasty Remains Steady over Past 15 YearsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Results of a Mayo Clinic study show the incidence of stroke or mini-stroke related to a coronary angioplasty remained steady over a 15-year period. (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - November 16, 2009 Category: Databases & Libraries Authors: Mayo Clinic Source Type: organizations

Mayo study shows stroke incidence related to angioplasty remains steady over past 15 yearsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Mayo Clinic) Results of a Mayo Clinic study show the incidence of stroke or mini-stroke related to a coronary angioplasty remained steady over a 15-year period. Researchers say this is good news because physicians now are performing the artery-opening procedure on older patients who are sicker and need more complicated treatment. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 16, 2009 Category: Global & Universal Source Type: news

PLATO: Ticagrelor benefits seen in STEMI subanalysisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The investigational oral antiplatelet therapy ticagrelor significantly reduces the risk for major cardiovascular events and all-cause mortality compared with clopidogrel in patients with ST-segment elevation myocardial infarction and planned primary percutaneous coronary intervention, a predefined subanalysis of the PLATO trial shows. (Source: MedWire News - Cardiology)
Source: MedWire News - Cardiology - November 16, 2009 Category: Cardiology Source Type: news

Cangrelor, an anti-platelet drug in development, shows disappointing trial resultsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Source: NEJM Area: News Two controlled trials of cangrelor, an anti-platelet drug in phase 3 trials, found it to be superior neither to placebo nor to a loading dose of clopidogrel when given before percutaneous coronary intervention (PCI).   The place of anti-platelet therapy in patients undergoing PCI is well established, however both the existing drugs used for pre-procedure loading (clopidogrel and prasugrel) require at least an hour for complete platelet inhibition, which is irreversible once it takes place. Many patients who might have PCI subsequently go on to CABG, and in these patients platelet inhibitio...
Source: NeLM - Cardiovascular Medicine - November 16, 2009 Category: Cardiology Source Type: organizations

RAPTOR trial supports routine use of radial artery access for PCIEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Interventionists should be encouraged to use radial artery access for percutaneous coronary intervention, suggest data presented here at the 2009 American Heart Association Scientific Sessions in Orlando, Florida, USA. (Source: MedWire News - Cardiology)
Source: MedWire News - Cardiology - November 16, 2009 Category: Cardiology Source Type: news

Functional measurements based on feature tracking of cine magnetic resonance images identify left ventricular segments with myocardial scarEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Feature tracking analysis of cine-MR displays velocity, displacement and strain in the radial and longitudinal direction and may be used for the detection of transmural scar. The accuracy and repeatability of the radial functional measurements is satisfactory and global measures agree. (Source: Cardiovascular Ultrasound)
Source: Cardiovascular Ultrasound - November 16, 2009 Category: Radiology Authors: Eva MaretTim TodtLars BrudinEva NylanderEva SwahnJan OhlssonJan Engvall Source Type: journals

High Residual Platelet Reactivity After Clopidogrel Loading and Long-Term Clinical Outcome After Drug-Eluting Stenting for Unprotected Left Main Coronary Disease.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions-HRPR after 600-mg clopidogrel loading is a strong marker of increased risk of cardiac death and DES thrombosis in patients receiving DES stenting for ULMD. Routine assessment of in vitro residual platelet reactivity after clopidogrel loading in patients with ULMD potentially suitable for DES-supported percutaneous coronary intervention should be considered to guide patient care decisions. PMID: 19917884 [PubMed - as supplied by publisher] (Source: Circulation)
Source: Circulation - November 16, 2009 Category: Cardiology Authors: Migliorini A, Valenti R, Marcucci R, Parodi G, Giuliani G, Buonamici P, Cerisano G, Carrabba N, Gensini GF, Abbate R, Antoniucci D Tags: Circulation Source Type: journals

AHA: Assays Help Predict Risk of Adverse Outcomes After PCI (CME/CE)Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
ORLANDO (MedPage Today) -- Three tests of platelet reactivity were able to predict which patients undergoing an elective percutaneous coronary intervention would have a thrombotic event within one year, despite antiplatelet therapy, researchers reported here. (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - November 15, 2009 Category: Cardiology Source Type: news

Clinical Trial Summary: Clopidogrel Versus Standard Therapy to Achieve Optimal Management of Platelet Inhibition–PLATFORM (CHAMPION PLATFORM — Presented at AHA 2009)Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The goal of this trial was to evaluate treatment with intravenous cangrelor compared with placebo among acute coronary syndrome (ACS) patients undergoing percutaneous coronary intervention (PCI). (Source: Cardiosource)
Source: Cardiosource - November 15, 2009 Category: Cardiology Source Type: organizations

Intravenous Platelet Blockade with Cangrelor during PCIEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Background Intravenous cangrelor, a rapid-acting, reversible adenosine diphosphate (ADP) receptor antagonist, might reduce ischemic events during percutaneous coronary intervention (PCI). Methods In this double-blind, placebo-controlled study, we randomly assigned 5362 ... (Source: New England Journal of Medicine)
Source: New England Journal of Medicine - November 15, 2009 Category: Internal Medicine Authors: Bhatt, D. L., Lincoff, A. M., Gibson, C. M., Stone, G. W., McNulty, S., Montalescot, G., Kleiman, N. S., Goodman, S. G., White, H. D., Mahaffey, K. W., Pollack, C. V., Manoukian, S. V., Widimsky, P., Chew, D. P., Cura, F., Manukov, I., Tousek, F., Jafar, Tags: ORIGINAL ARTICLES Source Type: journals

Journal Scan: Long-Term Prognostic Value of ST-Segment Resolution in Patients Treated With Fibrinolysis or Primary Percutaneous Coronary Intervention: Results From the DANAMI-2 (DANish trial in Acute Myocardial Infarction-2) (J Am Coll Cardiol 2009;54:1763-1769.)Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In the DANAMI-2 substudy, including 1,421 patients, the ST-segment elevation at baseline, preintervention, 90 minutes, and 4 hours was assessed. The ST-segment resolution was grouped as follows: 1) complete ≥70%; 2) partial 30% to (Source: Cardiosource)
Source: Cardiosource - November 13, 2009 Category: Cardiology Source Type: organizations

Timing of Clopidogrel Loading Not Crucial in PCIEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In clopidogrel-naive angina patients undergoing percutaneous coronary intervention (PCI), the timing of clopidogrel loading appears to have no significant effect on outcome, Greek researchers report. Reuters Health Information (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - November 12, 2009 Category: Consumer Health News Tags: Cardiology Source Type: news

Drug-Eluting Stent Fracture: Promise and Performance⁎Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
All promise outruns performance.—Ralph Waldo Emerson () The saga of drug-eluting stents (DES) continues from their hyperbolic introduction into clinical practice in 2003 through a period of scrupulous clinical safety introspection, emerging as the principal device therapy for percutaneous coronary intervention with renewed enthusiasm in today's era of prolonged oral dual antiplatelet therapy. Clinicians, researchers, industry, and regulatory agencies have gained wisdom from the many lessons taught in the global introduction of DES into clinical practice. As clinicians and scientists, we benefit from an organized cogniti...
Source: Journal of the American College of Cardiology - November 12, 2009 Category: Cardiology Authors: Andrew J. Carter Tags: Interventional Cardiology: Editorial Comment Source Type: journals

Emergent coronary artery bypass grafting for cardiogenic shock caused by very late drug-eluting stent thrombosisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We describe a case of cardiogenic shock caused by a very late drug-eluting stent (DES) thrombosis. The patient underwent emergent coronary artery bypass grafting (CABG) and was discharged home 15 days after the operation. The incidence of stent restenosis had been reduced by the use of DES, but the Achilles’ heel of DES is represented by a higher rate of stent thrombosis. In our case, the DES thrombosis occurred 5 years after its implantation, underlining the importance of prolonged dual antiplatelet therapy. Even though rare, this complication may be life-threatening. We believe that CABG provides better event-free ...
Source: General Thoracic and Cardiovascular Surgery - November 11, 2009 Category: Cardiovascular & Thoracic Surgery Tags: General Thoracic and Cardiovascular Surgery Source Type: journals

igh-Intensity Interval Training May Reduce In-Stent Restenosis Following Percutaneous Coronary Intervention with Stent ImplantationEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Exercise, in the form of high-intensity interval training, has proven preventive benefits for patients with coronary artery disease -- but do those benefits extend to stent restenosis? American Heart Journal (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - November 11, 2009 Category: Cardiology Tags: Cardiology Source Type: info

Safety and efficacy of drug-eluting vs. bare metal stents in patients with diabetes mellitusEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Source: Eur Heart J Area: News According to research published early online in the European Heart Journal, there is no difference in the combined outcome of death or myocardial infarction (MI) with up to 4 years of follow-up in patients with diabetes mellitus receiving drug-eluting stents (DES) compared with bare-metal stents (BMS).   Because diabetic patients are predisposed to more aggressive atherosclerosis and a higher risk for restenosis following percutaneous coronary intervention (PCI), researchers sought to evaluate the long-term safety and efficacy of DES vs. BMS in a cohort of patients with diabetes mel...
Source: NeLM - Surgery - November 11, 2009 Category: Surgery Source Type: organizations

Combined Assessment of Myocardial Perfusion and Late Gadolinium Enhancement in Patients After Percutaneous Coronary Intervention or Bypass Grafts: A Multicenter Study of an Integrated Cardiovascular Magnetic Resonance ProtocolEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions A combined CMR protocol for the assessment of myocardial perfusion and LGE is feasible for the detection of relevant coronary vessel stenosis even in patients who previously were treated by PCI or CAG in a routine clinical setting. However, diagnostic accuracy is reduced in patients with CABG. This could be due to different flow and perfusion kinetic. Further studies are needed to optimize the clinical protocols especially in post-surgical patients. (Source: Journal of the American College of Cardiology: Cardiovascular Imaging)
Source: Journal of the American College of Cardiology: Cardiovascular Imaging - November 9, 2009 Category: Radiology Authors: Bernhardt, P., Spiess, J., Levenson, B., Pilz, G., Hofling, B., Hombach, V., Strohm, O. Tags: Original Research Source Type: journals

Early Abciximab Has Benefits in High-Risk STEMI Patients: StudyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Giving abciximab to high-risk patients with ST-elevation myocardial infarction (STEMI) before transferring them for percutaneous coronary intervention (PCI) reduces 1-year mortality without increasing bleeding complications, new research shows. Reuters Health Information (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - November 9, 2009 Category: Cardiology Tags: Cardiology Source Type: info

New X-ray imaging modalities and their integration with intravascular imaging and interventionsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract  During recent years various techniques emerged providing more detailed images and insights in the cardiovascular system. C-Arm computed tomography is currently introduced in cardiac imaging offering the potential of three dimensional imaging of the coronary arteries, the cardiac chambers, venous system and a variety of anatomic anomalies inside the interventional environment. Furthermore it might enable perfusion imaging during percutaneous coronary intervention (PCI). Intravascular ultrasound (IVUS) and optical coherence tomography (OCT) are meanwhile established tools for detailed assessment of th...
Source: The International Journal of Cardiovascular Imaging - November 7, 2009 Category: Radiology Tags: The International Journal of Cardiovascular Imaging (formerly Cardiac Imaging) Source Type: journals

PPIs can be used with thienopyridinesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Clinicians do not need to avoid concomitant use of proton pump inhibitors during percutaneous coronary intervention surgery in acute coronary syndrome patients receiving clopidogrel or prasugrel, study findings indicate. (Source: MedWire News - Anesthesiology)
Source: MedWire News - Anesthesiology - November 6, 2009 Category: Anesthesiology Source Type: news

Combined PCI and minimally invasive heart valve surgery for high-risk patientsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Opinion statement  Combined coronary artery valvular heart disease is a major cause of morbidity and mortality in the adult patient population. The standard treatment for such disease has been open heart surgery in which coronary artery bypass grafting (CABG) is performed concurrently with valve surgery using a median sternotomy and cardiopulmonary bypass. With the increasing complexity of patients referred to surgery, some patients may prove to be poor surgical candidates for combined valve and CABG surgery. In certain selected patients who fall into this category, valve surgery and percutaneous coronary int...
Source: Current Treatment Options in Cardiovascular Medicine - November 5, 2009 Category: Cardiology Tags: Current Treatment Options in Cardiovascular Medicine Source Type: journals