Coronary Artery Bypass Graft
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Cardiopulmonary Bypass Priming Using a High Dose of a Balanced Hydroxyethyl Starch Versus an Albumin-Based Priming Strategy.
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CONCLUSION: High-volume priming of the CPB circuit with a modern balanced HES solution resulted in reduced inflammation, less endothelial damage, and fewer alterations in renal tubular integrity compared with an albumin-based priming. Coagulation including platelet function was better preserved with high-dose balanced HES CPB priming compared with albumin-based CPB priming.
PMID: 19923501 [PubMed - as supplied by publisher] (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - November 20, 2009 Category: Anesthesiology Authors: Boldt J, Suttner S, Brosch C, Lehmann A, Röhm K, Mengistu A Tags: Anesth Analg Source Type: journals
Radial Artery Cannulation: A Comprehensive Review of Recent Anatomic and Physiologic Investigations.
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Consistent anatomic accessibility, ease of cannulation, and a low rate of complications have made the radial artery the preferred site for arterial cannulation. Radial artery catheterization is a relatively safe procedure with an incidence of permanent ischemic complications of 0.09%. Although its anatomy in the forearm and the hand is variable, adequate collateral flow in the event of radial artery thrombosis is present in most patients. Harvesting of the radial artery as a conduit for coronary artery bypass grafting, advances in plastic and reconstructive surgery of the hand, and its use as an entry site for cardiac ...
Source: Anesthesia and Analgesia - November 20, 2009 Category: Anesthesiology Authors: Brzezinski M, Luisetti T, London MJ Tags: Anesth Analg Source Type: journals
Aspirin and clopidogrel use in the early postoperative period following on-pump and off-pump coronary artery bypass grafting
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Conclusions: Early postoperative clopidogrel combined with aspirin may be safe and beneficial compared with perioperative aspirin treatment alone, in both on-pump and off-pump coronary artery bypass grafting. However, a possibility of selection bias calls for randomized controlled trials to confirm our findings. (Source: The Journal of Thoracic and Cardiovascular Surgery)
Source: The Journal of Thoracic and Cardiovascular Surgery - November 20, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Dae Hyun Kim, Constantine Daskalakis, Scott C. Silvestry, Mital P. Sheth, Andrew N. Lee, Suzanne Adams, Sam Hohmann, Sofia Medvedev, David J. Whellan Tags: Perioperative Management Source Type: journals
Telephone-Delivered Care For Treating Depression After Coronary Artery Bypass Graft Surgery Appears To Improve Outcomes
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Patients who received telephone-delivered collaborative care for treatment of depression after coronary artery bypass graft surgery reported greater improvement in measures of quality of life, physical functioning and mood than patients who received usual care, according to a study in the November 18 issue of JAMA. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 20, 2009 Category: Consumer Health News Tags: Heart Disease Source Type: news
Telephone-Delivered Care For Treating Depression After Coronary Artery Bypass Graft Surgery Appears To Improve Outcomes
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Patients who received telephone-delivered collaborative care for treatment of depression after coronary artery bypass graft surgery reported greater improvement in measures of quality of life, physical functioning and mood than patients who received usual care, according to a study in the November 18 issue of JAMA. The study is being released early online because of its presentation at an American Heart Association scientific conference. (Source: Cardiovascular / Cardiology News From Medical News Today)
Source: Cardiovascular / Cardiology News From Medical News Today - November 20, 2009 Category: Cardiology Tags: Heart Disease Source Type: news
[Anesthesic management in telerobotic totally endoscopic coronary artery bypass grafting.]
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CONCLUSION: Although the hemodynamics and the respiratory function in totally endoscopic coronary artery bypass grafting are both extremely unstable as a result of single right-lung ventilation and surgical procedure, the appropriate administration of vasopressors and adjustment of respiratory function in anesthesia can allow the completion of the procedure with acceptable hemodynamics.
PMID: 19923068 [PubMed - as supplied by publisher] (Source: Journal of Southern Medical University)
Source: Journal of Southern Medical University - November 20, 2009 Category: Universities & Medical Training Authors: Zhou Q, Wang G, Gao CQ, Chen TT Tags: Nan Fang Yi Ke Da Xue Xue Bao Source Type: journals
A Comparison of Atrial Arrhythmias After Heart or Double-Lung Transplantation at a Single Center: Insights Into the Mechanism of Post-Operative Atrial Fibrillation
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Conclusions: In heart transplant recipients, AF is uncommon and occurs in the setting of myocardial dysfunction and graft rejection. In contrast, AF is more common after lung transplantation despite the absence of graft rejection and cardiac dysfunction. Pulmonary vein isolation alone cannot explain the discrepancy in AF incidence between heart transplant recipients and double-lung transplant recipients. Cardiac autonomic denervation may have a protective effect for heart transplant patients in the post-operative setting. (Source: Journal of the American College of Cardiology)
Source: Journal of the American College of Cardiology - November 19, 2009 Category: Cardiology Authors: José Dizon, Kimberly Chen, Matthew Bacchetta, Michael Argenziano, Donna Mancini, Angelo Biviano, Joshua Sonett, Hasan Garan Tags: QUARTERLY FOCUS ISSUE: HEART RHYTHM DISORDERS Source Type: journals
Atrial Fibrillation After Major Thoracic Surgery: New Insights Into Underlying Mechanisms⁎
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Atrial fibrillation (AF) is a common complication in patients undergoing major thoracic surgery (). It is most frequently observed acutely after valve surgery and/or coronary artery bypass graft surgery (CABG), but it can also manifest after lung and heart transplantation procedures (). Although mechanisms underlying this unique form of AF have not been adequately elucidated, it is likely that these involve a combination of pericardial inflammation, myocardial ischemia, catecholamine surge, autonomic imbalance, interstitial fluid mobilization, tissue rejection, and so forth (). It is interesting to note that AF is observed...
Source: Journal of the American College of Cardiology - November 19, 2009 Category: Cardiology Authors: Sanjay Dixit Tags: Editorial Comment Source Type: journals
Initial medical rather than interventional management more cost-effective for most diabetic patients with stable CHD
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Source: Circulation
Area: News
The most cost-effective initial treatment for diabetic patients with stable coronary heart disease (CHD) depends on the seriousness of their CHD: intensive medical management appears more cost-effective than percutaneous coronary intervention (PCI) in less seriously affected patients, however those with more severe disease should probably proceed straight to CABG (coronary artery bypass grafting).
These conclusions come from pre-specified secondary outcome and economic analyses of the BARI-2D trial (Bypass Angioplasty Revascularization Investigation 2 Diabetes), published early on...
Source: NeLM - Cardiovascular Medicine - November 19, 2009 Category: Cardiology Source Type: organizations
Prognostic value of coronary revascularisation-related myocardial injury: a cardiac magnetic resonance imaging study
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Conclusions:
Myocardial injury during PCI or CABG, identified by DE-CMR, adversely affects clinical outcome. This suggests the benefits from revascularisation could partially be offset by new myocardial injury caused by the intervention itself. (Source: Heart)
Source: Heart - November 18, 2009 Category: Cardiology Authors: Rahimi, K, Banning, A P, Cheng, A S H, Pegg, T J, Karamitsos, T D, Channon, K M, Darby, S, Taggart, D P, Neubauer, S, Selvanayagam, J B Tags: Editor's choice, Drugs: cardiovascular system, Interventional cardiology, Acute coronary syndromes, Percutaneous intervention, Clinical diagnostic tests Original articles Source Type: journals
AHA: Beating Heart Bypass Better for Brain than PCI (CME/CE)
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ORLANDO (MedPage Today) -- Percutaneous coronary intervention (PCI) may be worse for the brain than coronary artery bypass grafting (CABG) without the heart-lung machine, researchers reported here. (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - November 18, 2009 Category: Cardiology Source Type: news
CASCADE: No Significant Benefit of Clopidogrel in Reducing Graft Disease After CABG
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Dual antiplatelet therapy did not significantly reduce vein graft intimal hyperplasia compared with aspirin alone over 12 months. Heartwire (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - November 18, 2009 Category: Cardiology Tags: Cardiology Source Type: info
Epicardial Cardiac Basal Annuloplasty: Preliminary Findings on Extra-cardiac Mitral Valve Repair
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This study was conducted to assess the efficacy and safety of the concept BACE device in patients with moderate functional mitral valve regurgitation as a result of symptomatic coronary artery disease and heart failure.Methods: The study involved a group of patients who had complex cardiac surgery between January 2000 and December 2001 at the University of Melbourne Campus Hospitals, Melbourne, Australia. Twelve patients with ischaemic heart disease, congestive heart failure, and moderate functional mitral regurgitation (MR) (minimum 2+) underwent the BACE procedure along with coronary artery bypass grafting and/or left ve...
Source: Heart, Lung & Circulation - November 18, 2009 Category: Cardiology Authors: Jai Raman, David Hare, Meg Storer, Mitsumasa Hata Tags: Original Articles Source Type: journals
Bypassing the Blues: How Simple Collaborative Care Can Help Tackle Depression After CABG Surgery
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Depression after coronary artery bypass surgery is often overlooked by physicians but is associated with worse outcomes. A new US study illustrates a simple telephone-based approach to tackle this, with nurses encouraging patients to seek help from their primary-care doctors and providing ongoing feedback and review. Heartwire (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - November 18, 2009 Category: Consumer Health News Tags: Cardiology Source Type: news
Jugular bulb desaturation during off-pump coronary artery bypass surgery
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Conclusion Changes in
SvO2
and
PaCO2
were associated with jugular bulb oxygen saturation, and
SvO2
≤ 70%,
PaCO2
≤ 40 mmHg, and CVP ≥ 8 mmHg had a significant odds ratio for jugular bulb desaturation. We suggest that achieving normal
values of
SvO2
,
PaCO2
, and CVP may be important to prevent cerebral desaturation during OPCAB.
Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00540-009-0794-8Authors
Norikazu Miura, National Cardiovascular Center Department of Anesthesiology 5-7-1 Fujishirodai Suita, Osaka 565-8565 JapanKenji Yoshitani, National Cardiovascula...
Source: Journal of Anesthesia - November 17, 2009 Category: Anesthesiology Tags: Journal of Anesthesia Source Type: journals
Treating Depression After Surgery Speeds Recovery
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A simple telephone intervention improved mood, physical functioning, and overall quality of life in patients who were depressed after heart bypass surgery, researchers reported in a late breaking clinical trial here at the American Heart Association Scientific Sessions 2009. Source: Reuters Health
Related MedlinePlus Topics: Coronary Artery Bypass Surgery, Depression (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - November 17, 2009 Category: Consumer Health News Source Type: consumer
Stem Cells May Improve Heart Bypass Results
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Patients who had bone marrow transplant with surgery did better, study finds Source: HealthDay
Related MedlinePlus Topics: Coronary Artery Bypass Surgery, Stem Cells (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - November 17, 2009 Category: Consumer Health News Source Type: consumer
Telephone-Delivered Collaborative Care for Treating Post-CABG Depression: A Randomized Controlled Trial [Original Contribution]
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Conclusion Compared with usual care, telephone-delivered collaborative care for treatment of post-CABG depression resulted in improved HRQL, physical functioning, and mood symptoms at 8-month follow-up.
Trial Registration clinicaltrials.gov Identifier: NCT00091962
Published online November 16, 2009 (doi:10.1001/jama.2009.1670). (Source: JAMA)
Source: JAMA - November 17, 2009 Category: Journals (General) Authors: Rollman, B. L., Belnap, B. H., LeMenager, M. S., Mazumdar, S., Houck, P. R., Counihan, P. J., Kapoor, W. N., Schulberg, H. C., Reynolds, C. F. Tags: Revascularization, Informatics/ Internet in Medicine, Telemedicine, Medical Practice, Medical Practice, Other, Psychiatry, Depression, Cardiovascular System, Surgery, Surgical Interventions, Cardiovascular/ Cardiothoracic Surgery, Randomized Controlled Tr Source Type: journals
Long-term follow-up after minimal invasive direct coronary artery bypass grafting procedure: a multi-factorial retrospective analysis at 1000 patient-years [Institutional report - Cardiac general]
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We provide a multi-factorial long-term follow-up following minimal invasive direct coronary artery bypass grafting (MIDCABG) to evaluate the long-term efficacy. From 1996 onwards, 390 patients underwent MIDCABG (follow-up: 30.0±11.2 months). We analyzed peri-operative and postoperative complications (<30 days) and we obtained early and late angiography. Cumulative follow-up was 1000 patient-years. Early postoperative mortality was 0.8% and myocardial infarction occurred in 1.3% of all patients. Early postoperative angiography (<30 days) was obtained in 238 patients (66.3%) and revealed patency i...
Source: Interactive CardioVascular and Thoracic Surgery - November 17, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Kofidis, T., Emmert, M. Y., Paeschke, H. G., Emmert, L. S., Zhang, R., Haverich, A. Tags: Institutional report - Cardiac general Source Type: journals
Graft fixation with a side graft holder for sequential and composite graft anastomosis in coronary artery bypass surgery [Work in progress report - Coronary]
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The purpose of this study was to assess the feasibility and effectiveness of graft fixation with a novel side graft holder for sequential or composite graft anastomosis in coronary artery bypass grafting (CABG). Records of 34 patients who underwent CABG using sequential or composite graft anastomosis technique were reviewed. The device was used on 47 anastomoses (sequential=43; composite graft=4). Excellent fixation and visualization of the graft was obtained in all patients without graft injury. Postoperative angiographic patency rate of distal anastomoses was 95.2% (arterial, 91.2%; venous, 96.7%). All sequential and com...
Source: Interactive CardioVascular and Thoracic Surgery - November 17, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Shimamura, Y., Hayashi, I. Tags: Work in progress report - Coronary Source Type: journals
Telephone-Delivered Care For Treating Depression After CABG Surgery Appears To Improve Outcomes
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Patients who received telephone-delivered collaborative care for treatment of depression after coronary artery bypass graft surgery reported greater improvement in measures of quality of life, physical functioning and mood than patients who received usual care, according to a study in the November 18 issue of JAMA. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 17, 2009 Category: Consumer Health News Tags: Heart Disease Source Type: news
Telephone-Delivered Care For Treating Depression After CABG Surgery Appears To Improve Outcomes
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Patients who received telephone-delivered collaborative care for treatment of depression after coronary artery bypass graft surgery reported greater improvement in measures of quality of life, physical functioning and mood than patients who received usual care, according to a study in the November 18 issue of JAMA. The study is being released early online because of its presentation at an American Heart Association scientific conference. (Source: Cardiovascular / Cardiology News From Medical News Today)
Source: Cardiovascular / Cardiology News From Medical News Today - November 17, 2009 Category: Cardiology Tags: Heart Disease Source Type: news
AHA: Aspirin alone good enough to prevent vein graft disease
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Orlando, Fla.—The addition of clopidogrel to aspirin did not lead to a significant reduction in vein graft intimal hyperplasia during the first year after CABG, according to the CASCADE trial presented Monday during the late-breaking clinical trials session at the 2009 American Heart Association conference. (Source: Cardiovascular Business News)
Source: Cardiovascular Business News - November 17, 2009 Category: Cardiology Tags: Latest News Source Type: news
Comparison of compression stocking with elastic bandage in reducing postoperative edema in coronary artery bypass graft patient
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The objective of this study was to compare the efficacy of medical compression stocking (TED) and elastic bandage-type on donor limbs after CABG. The peripheries of lower limbs were measured at four regions (A: end of tarsal bones, H: heel , B: immediately above the ankle, C: largest circumference of the calf) at admission in 295 patients how CABG candidates and differences in these measurement points at discharge compared to measurements at admission time were calculated. The difference was considered as a measure of the effectiveness of two types of compression to prevent postoperative edema in donor limbs after CABG. Th...
Source: Journal of Vascular Nursing - November 17, 2009 Category: Nursing Authors: Khoshgoftar Zohreh, Ayat Esfahani Farah, Marzban Mehrab, Salehi Omran Abbas, Hajighasemi Alireza, Movaghar Soraya, Saadat Soheil Tags: Articles Source Type: journals
CASCADE: No significant benefit of clopidogrel in reducing graft disease after CABG
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Dual antiplatelet therapy did not significantly reduce vein graft intimal hyperplasia compared with aspirin alone over 12 months. (Source: theHeart.org)
Source: theHeart.org - November 17, 2009 Category: Cardiology Source Type: info
CASCADE: No added benefit with clopidogrel for saphenous vein grafts after CABG
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The addition of clopidogrel to aspirin failed to significantly reduce intimal hyperplasia in the saphenous vein grafts of patients who underwent coronary artery bypass graft compared with aspirin alone. (Source: MedWire News - Thrombosis)
Source: MedWire News - Thrombosis - November 17, 2009 Category: Internal Medicine Source Type: news
CASCADE: No added benefit with clopidogrel for saphenous vein grafts after CABG
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The addition of clopidogrel to aspirin failed to significantly reduce intimal hyperplasia in the saphenous vein grafts of patients who underwent coronary artery bypass graft compared with aspirin alone. (Source: MedWire News - Cardiology)
Source: MedWire News - Cardiology - November 17, 2009 Category: Cardiology Source Type: news
Phone Care Can Help Combat Post-Heart Surgery Depression
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A telephone-based care program, conducted by nurses in collaboration with patients' primary care
physicians and supervised by a psychiatrist, helps combat post-surgical depression among coronary artery bypass
graft patients, according to a study published online Nov. 16 in the Journal of the American Medical
Association. (Source: Modern Medicine)
Source: Modern Medicine - November 17, 2009 Category: Journals (General) Source Type: info
Economic Outcomes of Treatment Strategies for Type 2 Diabetes Mellitus and Coronary Artery Disease in the Bypass Angioplasty Revascularization Investigation 2 Diabetes Trial.
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Conclusions-Prompt coronary revascularization significantly increases costs among patients with type 2 diabetes mellitus and stable coronary disease. The strategy of medical therapy (with delayed revascularization as needed) appears to be cost-effective compared with the strategy of prompt coronary revascularization among patients identified a priori as suitable for percutaneous coronary intervention. Clinical Trial Registration-URL: http://www.clinicaltrials.gov. Unique Identifier: NCT00006305.
PMID: 19920002 [PubMed - as supplied by publisher] (Source: Circulation)
Source: Circulation - November 17, 2009 Category: Cardiology Authors: Hlatky MA, Boothroyd DB, Melsop KA, Kennedy L, Rihal C, Rogers WJ, Venkitachalam L, Brooks MM, Tags: Circulation Source Type: journals
The Bypass Angioplasty Revascularization Investigation 2 Diabetes Randomized Trial of Different Treatment Strategies in Type 2 Diabetes Mellitus With Stable Ischemic Heart Disease. Impact of Treatment Strategy on Cardiac Mortality and Myocardial Infarction.
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Conclusions-In many patients with type 2 diabetes mellitus and stable ischemic coronary disease in whom angina symptoms are controlled, similar to those enrolled in the percutaneous coronary intervention stratum, intensive medical therapy alone should be the first-line strategy. In patients with more extensive coronary disease, similar to those enrolled in the coronary artery bypass grafting stratum, prompt coronary artery bypass grafting, in the absence of contraindications, intensive medical therapy, and an insulin sensitization strategy appears to be a preferred therapeutic strategy to reduce the incidence of MI. Clinic...
Source: Circulation - November 17, 2009 Category: Cardiology Authors: Chaitman BR, Hardison RM, Adler D, Gebhart S, Grogan M, Ocampo S, Sopko G, Ramires JA, Schneider D, Frye RL, Tags: Circulation Source Type: journals
Bypassing the blues: How simple collaborative care can help tackle depression after CABG surgery
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Depression after coronary artery bypass surgery is often overlooked by physicians but is associated with worse outcomes. A new US study illustrates a simple telephone-based approach to tackle this, with nurses encouraging patients to seek help from their primary-care doctors and providing ongoing feedback and review. (Source: theHeart.org)
Source: theHeart.org - November 16, 2009 Category: Cardiology Source Type: info
AHA: Phone Calls Ease Post-CABG Depression (CME/CE)
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ORLANDO (MedPage Today) -- For patients suffering depression after coronary artery bypass grafting (CABG), regular phone calls from a nurse may boost antidepressive therapy as much as psychotherapy and medication, researchers found. (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - November 16, 2009 Category: Cardiology Source Type: news
A Randomized Comparison of Transradial Versus Transfemoral Approach for Coronary Angiography and Angioplasty
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Conclusions
The findings of the present study show that transradial coronary angiography and angioplasty are safe, feasible, and effective with similar results to those of the transfemoral approach. However, procedural duration and radiation exposure are higher using the transradial access. In contrast to the transfemoral route, the rate of major vascular complications was negligible using the transradial approach. (Source: Journal of the American College of Cardiology: Cardiovascular Interventions)
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - November 16, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Brueck, M., Bandorski, D., Kramer, W., Wieczorek, M., Holtgen, R., Tillmanns, H. Tags: Clinical Research Source Type: journals
Mechanism and Predictors of Failed Transradial Approach for Percutaneous Coronary Interventions
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Conclusions
Transradial approach PCI can be performed by low-to-intermediate volume operators with standard equipment with a low failure rate. Age >75 years, prior coronary artery bypass graft surgery, and short stature are independent predictors of TR-PCI failure. Appropriate patient selection and careful risk assessment are needed to maximize benefits offered by TR-PCI. (Source: Journal of the American College of Cardiology: Cardiovascular Interventions)
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - November 16, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Dehghani, P., Mohammad, A., Bajaj, R., Hong, T., Suen, C. M., Sharieff, W., Chisholm, R. J., Kutryk, M. J.B., Fam, N. P., Cheema, A. N. Tags: Mini-Focus Issue: Transradial Approach Source Type: journals
Aspirin without Plavix as good after heart bypass
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ORLANDO, Florida (Reuters) - Aspirin alone proved as effective as aspirin plus the blood clot preventer Plavix in keeping coronary artery bypass grafts open during the first year after surgery, according to a study released on Monday. (Source: Reuters: Health)
Source: Reuters: Health - November 16, 2009 Category: Consumer Health News Tags: healthNews Source Type: news
Aspirin Without Plavix As Good After Heart Bypass
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Aspirin alone proved as effective as aspirin plus the blood clot preventer Plavix in keeping coronary artery bypass grafts open during the first year after surgery, according to a study released on Monday. Source: Reuters Health
Related MedlinePlus Topics: Blood Thinners, Coronary Artery Bypass Surgery, Pain Relievers (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - November 16, 2009 Category: Consumer Health News Source Type: consumer
Telephone-delivered care for treating depression after CABG surgery appears to improve outcomes
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(JAMA and Archives Journals) Patients who received telephone-delivered collaborative care for treatment of depression after coronary artery bypass graft surgery reported greater improvement in measures of quality of life, physical functioning and mood than patients who received usual care, according to a study in the Nov. 18 issue of JAMA. The study is being released early online because of its presentation at an American Heart Association scientific conference. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - November 16, 2009 Category: Global & Universal Source Type: news
Bypassing the blues: Treatment for depression post-bypass surgery improves quality of life
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(University of Pittsburgh Schools of the Health Sciences) Coronary artery bypass graft patients who were screened for depression after surgery and then cared for by a nurse-led team of health care specialists via telephone reported improved quality of life and physical function compared to those who received their doctors' usual care, according to a study from the University of Pittsburgh School of Medicine. Study findings will be published in the Nov. 18 edition of the Journal of the American Medical Association. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - November 16, 2009 Category: Global & Universal Source Type: news
Cangrelor, an anti-platelet drug in development, shows disappointing trial results
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Source: NEJM
Area: News
Two controlled trials of cangrelor, an anti-platelet drug in phase 3 trials, found it to be superior neither to placebo nor to a loading dose of clopidogrel when given before percutaneous coronary intervention (PCI).
The place of anti-platelet therapy in patients undergoing PCI is well established, however both the existing drugs used for pre-procedure loading (clopidogrel and prasugrel) require at least an hour for complete platelet inhibition, which is irreversible once it takes place. Many patients who might have PCI subsequently go on to CABG, and in these patients platelet inhibitio...
Source: NeLM - Cardiovascular Medicine - November 16, 2009 Category: Cardiology Source Type: organizations
Validating a 3‐Point Prediction Rule for Surgical Site Infection after Coronary Artery Bypass Surgery
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Conclusions. The NNIS risk index predicts the risk of SSI associated with many procedures, but it has limited use in predicting the risk of SSI after CABG surgery. The new Australian Clinical Risk Index stratified patients into discrete groups associated with increased risk of SSI. Data from our study support the use of this new risk index in the US population. (Source: Infect Control Hosp Epidemiol Latest Issue)
Source: Infect Control Hosp Epidemiol Latest Issue - November 13, 2009 Category: Epidemiology Tags: article ORIGINAL ARTICLE Source Type: journals
Saphenous vein harvesting site dermatoses in eastern India.
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We report the cutaneous effects at the saphenous vein harvesting sites in 21 patients who underwent CABG.
PMID: 19903441 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - November 13, 2009 Category: Dermatology Authors: Ghosh SK, Bandyopadhyay D Tags: Dermatol Online J Source Type: journals
Intraoperative Continuous Venovenous Hemofiltration during Coronary Surgery [ORIGINAL ARTICLE]
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Postoperative continuous venovenous hemofiltration decreases acute renal failure in patients with moderate renal dysfunction undergoing coronary artery bypass grafting, but it prolongs intensive care unit stay. We developed a simple method to connect a hemofiltration machine to the cardiopulmonary bypass system. To evaluate the benefit of intraoperative hemofiltration, 124 consecutive patients (mean age, 67 ± 6 years) with moderate renal dysfunction were studied. Surgery was preformed between January 2005 and May 2007. On-pump coronary artery bypass with hemofiltration was carried out in 40 patients (group A), 44 ha...
Source: Asian Cardiovascular and Thoracic Annals - November 12, 2009 Category: Cardiology Authors: Roscitano, Benedetto, Goracci, Capuano, Lucani, Sinatra Tags: ORIGINAL ARTICLE Source Type: journals
Surgery for Chronic Total Occlusion of the Left Main Stem: A 10-Year Experience [ORIGINAL ARTICLE]
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Chronic total occlusion of the left main stem coronary artery is rare. This retrospective study was conducted to evaluate outcomes of coronary artery bypass grafting between June 1998 and June 2008 in patients with chronic left main stem total occlusion. There were 17 (0.025%) cases detected in 67,082 coronary angiograms. The 14 men and 3 women had a mean age of 55.32 ± 9.2 years. Risk factors included diabetes in 8, hypertension in 6, and smoking in 6. Of 54 grafts applied, 15 were arterial and 39 were venous; 14 patients had 3-vessel disease, and 3 had 4-vessel disease. Three patients required intraaortic balloon ...
Source: Asian Cardiovascular and Thoracic Annals - November 12, 2009 Category: Cardiology Authors: Akhtar, Naqshband, Abid, Tufail, Waheed, Khan Tags: ORIGINAL ARTICLE Source Type: journals
Postoperative Pericardial Effusion and Posterior Pericardiotomy: Related? [ORIGINAL ARTICLE]
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Large pericardial effusions develop in 30% of patients after cardiac surgery, and reach their maximum size after 10 days, with tamponade in 1%. The aim of this prospective randomized case-controlled study was to assess the effectiveness of a posterior pericardiotomy in preventing early and late (>30 days) development of pericardial effusion. Between April 2005 and May 2006, 410 patients with a mean age of 68.4 ± 9.2 years undergoing coronary artery bypass grafting alone or combined with valve surgery were divided into 2 groups of 205 each. In the pericardiotomy group, a 4-cm longitudinal incision was made paralle...
Source: Asian Cardiovascular and Thoracic Annals - November 12, 2009 Category: Cardiology Authors: Bakhshandeh, Salehi, Radmehr, Sattarzadeh, Nasr, Sadeghpour Tags: ORIGINAL ARTICLE Source Type: journals
Hyperhomocysteinemia-Induced Myocardial Injury after Coronary Artery Bypass [ORIGINAL ARTICLE]
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Hyperhomocysteinemia and other major cardiovascular risk factors are associated with increased vascular oxidative stress. To access the effects preoperative plasma homocysteine levels and other atherosclerotic risk factors on myocardial ischemia-reperfusion injury after conventional coronary artery bypass, 213 patients with normal renal function were enrolled prospectively. Cardiac troponin T was measured postoperatively to determine myocardial injury. There was a significant relationship between hyperhomocysteinemia and postoperative peak troponin T. This was more marked in patients without major atherosclerotic risk fact...
Source: Asian Cardiovascular and Thoracic Annals - November 12, 2009 Category: Cardiology Authors: Thiengburanatham Tags: ORIGINAL ARTICLE Source Type: journals
Post-Sternotomy Hemorrhage due to Left Internal Thoracic Artery Pseudoaneurysm [CASE STUDIES]
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We describe a case of pseudoaneurysm of the internal thoracic artery, which was probably caused by infection. Four weeks after aortic valve replacement and coronary artery bypass surgery, an 84-year-old woman suddenly developed painful sternal instability and hypotension, with active hemorrhage from a left parasternal swelling. Selective arteriography revealed a pseudoaneurysm of the left internal thoracic artery. It was surgically excised, and the patient recovered uneventfully. (Source: Asian Cardiovascular and Thoracic Annals)
Source: Asian Cardiovascular and Thoracic Annals - November 12, 2009 Category: Cardiology Authors: Yamashiro, Kuniyoshi, Arakaki, Inafuku, Morishima, Kise Tags: CASE STUDIES Source Type: journals
Effects of Angiotensin-Converting Enzyme Inhibitor Therapy on Clinical Outcome in Patients Undergoing Coronary Artery Bypass Grafting
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Can this study settle the controversy over whether preoperative use of ACE inhibitors is safe for patients undergoing CABG? Journal of the American College of Cardiology (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - November 12, 2009 Category: Cardiology Tags: Cardiology Source Type: info
Use of Aspirin Versus Clopidogrel Plus Aspirin After Coronary Artery Bypass Graft Surgery
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Aspirin and clopidogrel together reduce the risk of recurrent thrombosis-related events in patients with acute coronary syndromes or stent revascularization and may reduce thrombosis-induced saphenous vein graft failure. In this retrospective, observational study, 4297 patients were assigned to 2 groups after coronary artery bypass graft surgery, based on medications prescribed at hospital discharge: aspirin only (n = 3318) or aspirin plus clopidogrel (n = 979). At 4-year follow-up, unadjusted survival was similar between the 2 groups (aspirin—clopidogrel, 87.9% vs aspirin-only, 88.8%, P = .43). After statistical adj...
Source: Clinical and Applied Thrombosis/Hemostasis - November 12, 2009 Category: Hematology Authors: Sanon, S., Lee, V.-V., Elayda, M., Wilson, J. M. Tags: Articles Source Type: journals
Emergency off-pump complete arterial revascularization in a patient with dextrocardia
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We describe complete emergency arterial coronary artery bypass grafting performed on the beating heart of a 73-year-old man
with situs inversus totalis and triple-vessel disease. The right internal mammary artery was anastomosed to the left anterior
descending artery in situ. The first and second obtuse marginal branches of the circumflex coronary and the posterior descending
branch of the right coronary artery were sequentially revascularized using the left internal mammary and radial arteries in
situ. The only abnormality was that the position of the heart mirrored that of a normal heart. Beating heart surgery appear...
Source: General Thoracic and Cardiovascular Surgery - November 11, 2009 Category: Cardiovascular & Thoracic Surgery Tags: General Thoracic and Cardiovascular Surgery Source Type: journals
Minimally invasive cardiac surgery for atrial fibrillation complicated by coronary artery disease: combination of video-assisted pulmonary vein isolation and minimally invasive direct coronary artery bypass
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Abstract Here we report a minimally invasive cardiac surgery procedure without sternotomy combining video-assisted bilateral pulmonary
vein isolation and minimally invasive direct coronary artery bypass as treatment for atrial fibrillation complicated by coronary
artery disease. The patient’s chest was accessed through a left anterolateral thoracotomy over the fourth intercostal space,
and the left internal thoracic artery (LITA) was harvested under direct vision. The left pulmonary veins were isolated electrically
by a bipolar radiofrequency clamp. Subsequently, the harvested LITA graft was anastomosed to...
Source: General Thoracic and Cardiovascular Surgery - November 11, 2009 Category: Cardiovascular & Thoracic Surgery Tags: General Thoracic and Cardiovascular Surgery Source Type: journals
