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Dry night cough as a marker of allergy in preschool children: the PARIS birth cohort
ConclusionsThis study provides evidence that persistent/late dry night cough may indicate allergy in preschool children. (Source: Pediatric Allergy and Immunology)
Source: Pediatric Allergy and Immunology - March 1, 2013 Category: Allergy & Immunology Authors: Fanny Rancière, Lydia Nikasinovic, Isabelle Momas Tags: Original Article Source Type: research

Acupuncture and Seasonal Allergic Rhinitis: Positive Impact, Questionable Durability
Acupuncture is widely used to treat symptoms of seasonal allergic rhinitis, but is there scientific evidence to support its use? Yes, and no. (Source: Consultant Live)
Source: Consultant Live - February 22, 2013 Category: Primary Care Source Type: news

[The long-term variability of FeNO in pregnant asthmatic women with controlled asthma.]
Conclusions: High long-term variability of fractional exhaled nitric oxide values revealed in pregnant women with well-controlled asthma indicates that changes in this parameter should be interpreted with caution while being used for asthma treatment monitoring. PMID: 23420427 [PubMed - as supplied by publisher] (Source: Pneumonologia i Alergologia Polska)
Source: Pneumonologia i Alergologia Polska - February 22, 2013 Category: Respiratory Medicine Authors: Dor-Wojnarowska A, Nittner-Marszalska M, Liebhart J, Marszalska H, Pawłowicz R, Gillert M, Kazimierczak A, -Filarska MK, Panaszek B Tags: Pneumonol Alergol Pol Source Type: research

Leukotriene (LT)C4 aggravates bleomycin‐induced pulmonary fibrosis in mice
ConclusionsOverexpression of LTC4, amplifies bleomycin‐induced pulmonary fibrosis in mice. Our findings suggest a role for LTC4 in lung fibrosis. (Source: Respirology)
Source: Respirology - February 22, 2013 Category: Respiratory Medicine Authors: Hirokuni Hirata, Masafumi Arima, Yasutsugu Fukushima, Kumiya Sugiyama, Takeshi Tokuhisa, Takeshi Fukuda Tags: Original Article Source Type: research

Acupuncture Relieves Hay Fever Symptoms
Hay fever sufferers who underwent 12 acupuncture sessions experienced fewer symptoms and required less antihistamine medication compared to a control group, researchers from Charite-University Medical Center, Berlin, Germany, reported in Annals of Internal Medicine. Hay fever, medically known as seasonal allergic rhinitis, is caused by allergies (usually) to plant pollen. Symptoms include a stuffy nose and itchy eyes. Standard treatment includes antihistamines. However, many patients find that antihistamines do not work... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - February 20, 2013 Category: Consumer Health News Tags: Allergy Source Type: news

News From The Annals Of Internal Medicine: Feb. 19, 2013
1. Acupuncture May be an Effective Alternative for Treating Seasonal Allergies Patients receiving acupuncture treatments for seasonal allergic rhinitis reported statistically significant improvements in symptoms and decreased use of medication compared to patients having standard treatment or sham acupuncture, but the clinical significance of the observed improvements is uncertain. Allergic rhinitis (stuffy or runny nose caused by allergies) is an extremely common condition that affects approximately 20 percent of the U.S. population... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - February 20, 2013 Category: Consumer Health News Tags: Allergy Source Type: news

Acupuncture May Help Ease Hay Fever
Study found patients who had treatment for 8 weeks fared better with symptoms (Source: WebMD Health)
Source: WebMD Health - February 19, 2013 Category: Consumer Health News Source Type: news

Acupuncture and Allergies
Source: HealthDay - Related MedlinePlus Pages: Acupuncture, Hay Fever (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - February 19, 2013 Category: Consumer Health News Source Type: news

Acupuncture Pins Hay Fever, but Briefly (CME/CE)
(MedPage Today) -- An 8-week course of acupuncture had statistically significant but short-lived benefits for people with seasonal allergic rhinitis, researchers reported. (Source: MedPage Today Allergy)
Source: MedPage Today Allergy - February 19, 2013 Category: Allergy & Immunology Source Type: news

Acupuncture May Help Ease Hay Fever
Title: Acupuncture May Help Ease Hay FeverCategory: Health NewsCreated: 2/18/2013 6:35:00 PMLast Editorial Review: 2/19/2013 12:00:00 AM (Source: MedicineNet Allergies General)
Source: MedicineNet Allergies General - February 19, 2013 Category: Allergy & Immunology Source Type: news

RCT: Acupuncture in patients with seasonal allergic rhinitis
Source: Ann Intern Med Area: News The Annals of Internal Medicine has featured the results of a randomised controlled trial evaluating the efficacy of acupuncture in the management of seasonal allergic rhinitis (SAR).   The multicentre trial involved patients seen at 6 hospital clinics and 32 private outpatient clinics. A total of 422 persons with SAR and IgE sensitisation to birch and grass pollen were recruited, and patients were randomised to receive one of the following three treatment arms:   . Acupuncture plus rescue medication (RM) (cetirizine) (n = 212) . Placebo acupuncture with RM (...
Source: NeLM - News - February 19, 2013 Category: Drugs & Pharmacology Source Type: news

The efficacy of radiofrequency volumetric tissue reduction of hypertrophied inferior turbinate in allergic rhinitis
Conclusion: RFVTR is safe and effective in treatment of ITH in allergic rhinitis patients. (Source: Indian Journal of Medical Sciences)
Source: Indian Journal of Medical Sciences - February 19, 2013 Category: Journals (General) Authors: Pradipta Kumar ParidaKrishnapriya SanthoshSivaraman GanesanGopalakrishnan SurianarayananSunil Kumar Saxena Source Type: research

The effects of acupuncture on seasonal allergic rhinitis.
Authors: PMID: 23420247 [PubMed - in process] (Source: Annals of Internal Medicine)
Source: Annals of Internal Medicine - February 19, 2013 Category: Internal Medicine Tags: Ann Intern Med Source Type: research

Acupuncture in patients with seasonal allergic rhinitis: a randomized trial.
CONCLUSION: Acupuncture led to statistically significant improvements in disease-specific quality of life and antihistamine use measures after 8 weeks of treatment compared with sham acupuncture and with RM alone, but the improvements may not be clinically significant. PRIMARY FUNDING SOURCE: German Research Foundation. PMID: 23420231 [PubMed - in process] (Source: Annals of Internal Medicine)
Source: Annals of Internal Medicine - February 19, 2013 Category: Internal Medicine Authors: Brinkhaus B, Ortiz M, Witt CM, Roll S, Linde K, Pfab F, Niggemann B, Hummelsberger J, Treszl A, Ring J, Zuberbier T, Wegscheider K, Willich SN Tags: Ann Intern Med Source Type: research

Acupuncture for Allergic Rhinitis: Role Remains QuestionableAcupuncture for Allergic Rhinitis: Role Remains Questionable
Statistical significance may not translate into clinical effects, researchers warn. Medscape Medical News (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - February 18, 2013 Category: Consumer Health News Tags: Internal Medicine News Source Type: news

Acupuncture May Help Ease Hay Fever
Study found patients who had treatment for 8 weeks fared better with symptoms (Source: Pulmonary Medicine News - Doctors Lounge)
Source: Pulmonary Medicine News - Doctors Lounge - February 18, 2013 Category: Respiratory Medicine Authors: webmaster at doctorslounge.com Tags: Pulmonology, Allergy, Alternative Medicine, News, Source Type: news

Could Acupuncture Help Relieve Seasonal Allergies?
Acupuncture may help improve seasonal allergy symptoms in some people with runny noses and watery eyes, according to a new study - but the effect seems to be small.Source: Reuters Health Related MedlinePlus Pages: Acupuncture, Hay Fever (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - February 18, 2013 Category: Consumer Health News Source Type: news

Novel cooperation between CX3CL1 and CCL26 inducing NK cell chemotaxis via CX3CR1: a possible mechanism for NK cell infiltration of the allergic nasal tissue
Conclusions and Clinical RelevanceOur results highlight a novel role for CX3CR1 in NK cell migration that may contribute to the NK cell trafficking to the allergic upper airway. This could be mediated largely by CX3CL1 and CCL26 stimulation of the tyrosine kinase pathway. (Source: Clinical and Experimental Allergy)
Source: Clinical and Experimental Allergy - February 17, 2013 Category: Allergy & Immunology Authors: A. E. El‐Shazly, H. C. Doloriert, B. Bisig, P. P. Lefebvre, P. Delvenne, N. Jacobs Tags: Original Article Source Type: research

The natural course of eczema from birth to age 7 years and the association with asthma and allergic rhinitis: A population-based birth cohort study
(Source: Allergy and Asthma Proceedings)
Source: Allergy and Asthma Proceedings - February 16, 2013 Category: Allergy & Immunology Authors: Shen, Chian-YinLin, Ming-ChihLin, Heng-KueiLin, Ching-HengFu, Lin-ShienFu, Yun-Chin Tags: Articles Source Type: research

Trends in Otolaryngologic Utilization of Computed Tomography for Sinonasal Disorders
ConclusionsDespite widespread availability of imaging and a strong prevalence of sinonasal diagnoses, otolaryngologists' CT ordering patterns have not resulted in increased utilization over the past 6 years. This suggests that otolaryngologists are remaining consistent in their ordering patterns for sinonasal CT. Level of Evidence2c. Laryngoscope, 2013 (Source: The Laryngoscope)
Source: The Laryngoscope - February 16, 2013 Category: ENT & OMF Authors: Neil Bhattacharyya Tags: Allergy/Rhinology Source Type: research

Comparison of antiallergic effects of pneumococcal conjugate vaccine and pneumococcal polysaccharide vaccine in a murine model of allergic rhinitis
Conclusion and Clinical RelevanceBoth PV and PCV suppressed the allergen‐specific T helper 2 response and induced regulatory T cells in a murine model of allergic rhinitis. However, PV and PCV may activate Treg cells via different mechanisms. Level of EvidenceN/A. Laryngoscope, 2013 (Source: The Laryngoscope)
Source: The Laryngoscope - February 16, 2013 Category: ENT & OMF Authors: Boo‐Young Kim, Ji‐Hyeon Shin, Hyang Rim Park, Sung Won Kim, Soo Whan Kim Tags: Allergy/Rhinology Source Type: research

Defining the Border-Zone between Episodic Migraine (EM) and Chronic Migraine (CM): Medical Comorbidities in the US Population (P03.110)
CONCLUSIONS: The comorbidity profiles of HFEM have much more in common with CM than with LFEM suggesting that HFEM and CM may bear a close biological relationship.Supported by: The American Migraine Prevalence and Prevention Study is funded through a research grant to the National Headache Foundation from Ortho-McNeil Neurologics, Inc., Titusville, NJ. Additional analyses were supported by a grant from Allergan Inc., Irvine, CA, to the National Headache Foundation. Abstract development was conducted independent of financial support.Disclosure: Dr. Serrano has received research support from Allergan, ENDO Pharmaceuticals, M...
Source: Neurology - February 14, 2013 Category: Neurology Authors: Serrano, D., Buse, D., Reed, M., Pavlovic, J., Vollbracht, S., Sollars, C. M., Lipton, R. Tags: P03 Headache: Epidemiology Source Type: research

Associations Between Obesity and Inflammatory Sinonasal Disorders
ConclusionsThe current data demonstrate an increased prevalence of adult obesity associated with both AR and CRS. Level of Evidence2b (Source: The Laryngoscope)
Source: The Laryngoscope - February 9, 2013 Category: ENT & OMF Authors: Neil Bhattacharyya Tags: General Otolaryngology Source Type: research

Diverging trends of chronic bronchitis and smoking habits between 1998 and 2010
Conclusions: Despite the significant reduction in current smoking, CB prevalence did not vary among young Italian adults. The temporal pattern of CB prevalence can only be partly explained by the increase of unemployment/premature retirement, asthma and allergic rhinitis, and suggests that other factors could have played a role. (Source: Respiratory Research)
Source: Respiratory Research - February 8, 2013 Category: Respiratory Medicine Authors: Simone AccordiniAngelo CorsicoIsa CerveriLeonardo AntonicelliFrancesco AttenaRoberto BonoLucio CasaliMarcello FerrariAlessandro FoisPierpaolo MarchettiPietro PirinaRoberta TassinariGiuseppe VerlatoRoberto de Marco Source Type: research

Worm Therapy For Hay Fever? More Research is Needed
04/18/2012, The Cochrane Library, Purposely infecting patients with hookworms or whipworms to treat hay fever and other immune-related diseases has been experimented with since the 1970s. A new review by The Cochrane Library concludes that current evidence doesn't yet support the use of this therapy. However, worm therapy does appear to be safe, the review's lead author says. (Source: Health Behavior News Service)
Source: Health Behavior News Service - February 6, 2013 Category: Consumer Health News Source Type: news

Latitude and UV-B exposure influence allergy and asthma risk
Individuals living closer to the equator are at an increased risk for hay fever, food allergy, and skin sensitization to house dust mites and molds, research shows. (Source: MedWire News - Respiratory)
Source: MedWire News - Respiratory - February 5, 2013 Category: Respiratory Medicine Source Type: news

Esophageal human beta-defensin expression in eosinophilic esophagitis.
Conclusion:Diminished expression of hBD1 and hBD3 may make the esophageal epithelium more susceptible to the development and/or perpetuation of EoE.Pediatric Research (2013); doi:10.1038/pr.2013.23. PMID: 23385963 [PubMed - as supplied by publisher] (Source: Pediatric Research)
Source: Pediatric Research - February 5, 2013 Category: Pediatrics Authors: Schroeder S, Robinson ZD, Masterson JC, Hosford L, Moore W, Pan Z, Harris R, Souza RF, Spechler SJ, Fillon SA, Furuta GT Tags: Pediatr Res Source Type: research

The multifunctional role of filaggrin in allergic skin disease
Filaggrin is a major structural protein in the stratum corneum of the epidermis. Mutations in the filaggrin gene are the most significant known genetic risk factor for the development of atopic dermatitis. Mutations in the human filaggrin gene (FLG) also confer risk for the associated allergic diseases of food allergy, asthma, and allergic rhinitis. These discoveries have highlighted the importance of skin barrier function in the pathogenesis of atopic diseases and have motivated a surge in research characterizing the filaggrin-deficient skin barrier and its consequences. In this review we discuss the mechanisms through wh...
Source: Journal of Allergy and Clinical Immunology - February 1, 2013 Category: Allergy & Immunology Authors: Maeve A. McAleer, Alan D. Irvine Tags: Mechanisms of allergic diseases Source Type: research

Intralymphatic allergen-specific immunotherapy: An effective and safe alternative treatment route for pollen-induced allergic rhinitis
Conclusions: Although this study is based on a limited number of patients, ILIT with grass-pollen or birch-pollen extracts appears to reduce nasal allergic symptoms without causing any safety problems. Hence, ILIT might constitute a less time-consuming and more cost-effective alternative to conventional subcutaneous allergen-specific immunotherapy. (Source: Journal of Allergy and Clinical Immunology)
Source: Journal of Allergy and Clinical Immunology - February 1, 2013 Category: Allergy & Immunology Authors: Terese Hylander, Leith Latif, Ulla Petersson-Westin, Lars Olaf Cardell Tags: Rhinitis, sinusitis, and upper airway disease Source Type: research

Associations of postnatal growth with asthma and atopy: the PROBIT Study
ConclusionCurrent height and weight are more strongly associated with the development of atopic phenotypes in childhood than patterns of infant and early childhood growth, which may well reflect reverse causality (atopy effects on growth) or residual confounding by an unknown common cause of growth and atopy. (Source: Pediatric Allergy and Immunology)
Source: Pediatric Allergy and Immunology - February 1, 2013 Category: Allergy & Immunology Authors: Emma L. Anderson, Abigail Fraser, Richard M. Martin, Michael S. Kramer, Emily Oken, Rita Patel, Kate Tilling Tags: Original Article Source Type: research

Rupatadine oral solution in children with persistent allergic rhinitis: A randomized, double‐blind, placebo‐controlled study
ConclusionsRupatadine oral solution (1 mg/ml) was significantly more effective than placebo in reducing nasal symptoms at 4 and 6 wk and was well tolerated overall. This is the first large clinical report on the efficacy of an H1 receptor antagonist in children with PER in both symptoms and quality of life. (Source: Pediatric Allergy and Immunology)
Source: Pediatric Allergy and Immunology - February 1, 2013 Category: Allergy & Immunology Authors: Paul Potter, Jorge F. Maspero, Jan Vermeulen, László Barkai, Ildikó Németh, Rene A. Baillieau, Jesús M. Garde, Josep Giralt, Alejandro Doménech, Iñaki Izquierdo, Antonio Nieto Tags: Original Article Source Type: research

Anaphylaxis in a tertiary adult allergy clinic: a retrospective review of 516 patients.
CONCLUSION: In this study, the second pattern of National Institute of Allergy and Infectious Disease (NIAID) and the Food Allergy and Anaphylaxis Network (FAAN) diagnostic criteria for anaphylaxis predominated among adult patients. Drugs were the leading triggering factor, followed by Hymenoptera stings, foods, latex, and exercise, respectively. Atopy, asthma, and allergic rhinitis were rarely detected. PMID: 23352528 [PubMed - in process] (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - January 30, 2013 Category: Allergy & Immunology Authors: Gelincik A, Demirtürk M, Yılmaz E, Ertek B, Erdogdu D, Colakoğlu B, Büyüköztürk S Tags: Ann Allergy Asthma Immunol Source Type: research

Association between latitude and allergic diseases: a longitudinal study from childhood to middle-age.
CONCLUSION: This is the first study, to our knowledge, to demonstrate a differential effect of atopic status on the relationship between latitude and current asthma. Our study demonstrates in a genetically and culturally similar group of individuals that geographic factors may a play role in the development of allergic disease. PMID: 23352525 [PubMed - in process] (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - January 30, 2013 Category: Allergy & Immunology Authors: Oktaria V, Dharmage SC, Burgess JA, Simpson JA, Morrison S, Giles GG, Abramson MJ, Walters EH, Matheson MC Tags: Ann Allergy Asthma Immunol Source Type: research

Dymista (azelastine and fluticasone) nasal spray approved in Europe
Source: BioSpace Area: News Dymista (azelastine and fluticasone) nasal spray has been approved in Europe for the treatment of seasonal and perennial allergic rhinitis.. Efficacy and safety have been evaluated in several studies with over 4000 patients, including a long-term safety study with more than 600 patients. Launches are anticipated in 2013 in several countries. (Source: NeLM - News)
Source: NeLM - News - January 25, 2013 Category: Drugs & Pharmacology Source Type: news

Allergic rhinitis and risk of erectile dysfunction – a nationwide population‐based study
ConclusionsPatients with AR appeared to be at higher risk of future ED, possibly in a severity‐dependent manner. (Source: Allergy)
Source: Allergy - January 25, 2013 Category: Allergy & Immunology Authors: V. Y.‐F. Su, C.‐J. Liu, M.‐Y. Lan, Y.‐M. Chen, K.‐C. Su, Y.‐C. Lee, T.‐J. Chen, K.‐T. Chou Tags: Original Article Source Type: research

Cigarette smoking is associated with high prevalence of chronic rhinitis and low prevalence of allergic rhinitis in men
ConclusionWe found that smoking was associated with a high prevalence of chronic rhinitis in both sexes and a low prevalence of allergic rhinitis in men. The associations were dose dependent and remained when adjusting for several possible confounders. (Source: Allergy)
Source: Allergy - January 25, 2013 Category: Allergy & Immunology Authors: J. Eriksson, L. Ekerljung, B.‐M. Sundblad, J. Lötvall, K. Torén, E. Rönmark, K. Larsson, B. Lundbäck Tags: Original Article Source Type: research

Allergic rhinitis in adolescence increases the risk of depression in later life: A nationwide population-based prospective cohort study
Abstract: Background: Many cross-sectional studies have suggested an association between allergic rhinitis (AR) and depression, but the timing relationship was not determined. Using a nationwide population-based prospective cohort study (1:4, age-/gender-matched), we hypothesized that AR in adolescence would increase the risk of depression in later life.Methods: In all, 1673 adolescents aged 12–15 that had AR between 1996 and 2000 were recruited for our study. Cases of major depressive disorder and any depressive disorder that occurred to the end of follow-up (December 31, 2010) were identified.Result: Adolescents with A...
Source: Journal of Affective Disorders - January 24, 2013 Category: Neurology Authors: Mu-Hong Chen, Tung-Ping Su, Ying-Sheue Chen, Ju-Wei Hsu, Kai-Lin Huang, Wen-Han Chang, Ya-Mei Bai Tags: Research Reports Source Type: research

Hay Fever as a Christmas Gift
New England Journal of Medicine, Volume 368, Issue 4, Page 393-394, January 2013. (Source: New England Journal of Medicine)
Source: New England Journal of Medicine - January 23, 2013 Category: Internal Medicine Tags: article Source Type: research

Allergic diseases in children with otitis media with effusion
Abstract: Objectives: Recent studies have shown that allergic diseases may be associated with the pathogenesis of recurrent otitis media with effusion (OME). We aimed to assess the relationship between OME and allergic diseases and other types of disease in children with OME. We also evaluated the between group differences in the characteristics of middle ear effusion.Materials and methods: We evaluated 370 patients diagnosed with OME between January 2007 and December 2012 and, as a control group, 100 children with no medical history of OME but who had undergone blood tests and MAST-CLA (multiple allergosorbent test – ch...
Source: International Journal of Pediatric Otorhinolaryngology - January 23, 2013 Category: ENT & OMF Authors: Chul Kwon, Ho Yun Lee, Myung Gu Kim, Sung Hyun Boo, Seung Geun Yeo Tags: Research papers Source Type: research

The self-reported density of truck traffic on residential streets and the impact on asthma, hay fever and eczema in young adolescents.
CONCLUSION: The findings suggest an aggravating effect of truck traffic on current asthma symptoms, but not on asthma, allergic rhinitis and eczema diagnoses. It seems that it probably has an impact as a direct respiratory irritant in early adolescence. PMID: 23352596 [PubMed - as supplied by publisher] (Source: Allergologia et Immunopathologia)
Source: Allergologia et Immunopathologia - January 23, 2013 Category: Allergy & Immunology Authors: Vlaski E, Stavric K, Seckova L, Kimovska Hristova M, Isjanovska R Tags: Allergol Immunopathol (Madr) Source Type: research

Cleaning jobs linked to adult asthma
Conclusion The results of this large study offer evidence of an association between occupational exposures and onset of asthma as a child. Importantly, it quantifies the proportion of asthma that is likely to be due to exposure to occupational agents. There are several imitations to this study: Despite the authors’ efforts to adjust their results for confounders, it is always possible that other factors such as a family history of asthma influenced the results. Asthma confirmed with lung function testing was less prevalent than self-reported asthma or wheezy bronchitis. This suggests that some of the self-reported ...
Source: NHS News Feed - January 22, 2013 Category: Consumer Health News Tags: Lifestyle/exercise Heart/lungs Source Type: news

Prevention of Allergic Rhinitis by Aldose Reductase Inhibition in a Murine Model.
Conclusion: These results indicate an important role of AR in the mediation of RWE-induced allergic rhinitis in mice and prevention by AR inhibitor, fidarestat offers a novel therapeutic approach to ameliorate allergic rhinitis. PMID: 23360251 [PubMed - as supplied by publisher] (Source: Inflammation and Allergy Drug Targets)
Source: Inflammation and Allergy Drug Targets - January 22, 2013 Category: Allergy & Immunology Authors: Yadav UC, Mishra R, Aguilera-Aguirre L, Sur S, Bolodgh I, Ramana KV, Srivatsava SK Tags: Inflamm Allergy Drug Targets Source Type: research

Nasal High-Mobility Group Box-1 Protein in Children with Allergic Rhinitis
Int Arch Allergy Immunol 2013;161:116–121 (DOI:10.1159/000345246) (Source: International Archives of Allergy and Immunology)
Source: International Archives of Allergy and Immunology - January 21, 2013 Category: Allergy & Immunology Source Type: research

Safety of mometasone furoate nasal spray in the treatment of nasal polyps in children
ConclusionsResults of this study confirm the safety profile of MFNS in pediatric patients with bilateral nasal polyps over 4 months, even at double the recommended pediatric dosage for allergic rhinitis. (Source: Pediatric Allergy and Immunology)
Source: Pediatric Allergy and Immunology - January 20, 2013 Category: Allergy & Immunology Authors: Victor Chur, Catherine B. Small, Paul Stryszak, Ariel Teper Tags: Original Article Source Type: research

House dust mite sublingual immunotherapy: a double‐blind, placebo‐controlled study in elderly patients with allergic rhinitis
Conclusions & Clinical RelevanceSublingual allergen‐specific immunotherapy in elderly patients with a HDM allergy to D. pteronyssinus and D. farinae generated a significant clinical improvement in the active group compared with the placebo group, particularly during the heating season. This therapy was well tolerated. (Source: Clinical and Experimental Allergy)
Source: Clinical and Experimental Allergy - January 18, 2013 Category: Allergy & Immunology Authors: A. Bozek, B. Ignasiak, B. Filipowska, J. Jarzab Tags: Original Article Source Type: research

Aberrant dendritic cell function conditions Th2‐cell polarization in allergic rhinitis
ConclusionIn allergic rhinitis, DCs are altered not only locally but also in the systemic circulation. mDCs and pDCs increased in airway and skin tissues exposed to the allergen and displayed reduced production of IL‐10 and ‘type 1 signals’ (IL‐12, IFN‐α) both locally and in blood. Functional studies showed that this results in preferential Th2/Th17‐cell polarization and impaired generation by blood DCs of IL‐10+ T cells, linking systemic DC dysfunction and biased T‐cell responses. (Source: Allergy)
Source: Allergy - January 18, 2013 Category: Allergy & Immunology Authors: C. Pilette, M. R. Jacobson, C. Ratajczak, B. Detry, G. Banfield, J. VanSnick, S. R. Durham, K. T. Nouri‐Aria Tags: Original Article Source Type: research

Asthma, eczema may be linked to fast food
Teenagers and young children who eat fast food could be increasing their risk of developing asthma, eczema and hay fever, according to a study published Monday in the British Medical Journal's respiratory journal Thorax. (Source: WDSU.com - Health)
Source: WDSU.com - Health - January 15, 2013 Category: Consumer Health News Source Type: news

Fast Food Linked To Asthma And Eczema In Kids
Kids who eat fast food three or more times a week are likely to have more severe allergic asthma, rhinitis (hay fever), and eczema. The finding came from new international research and was published in the journal Thorax. Similarly, a previous study demonstrated that the benefits of breastfeeding in preventing asthma are cancelled out by eating fast food once or twice a week. The results of the new study motivated the investigators to believe that a fast food diet may be playing a part in the increase in these conditions... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - January 15, 2013 Category: Consumer Health News Tags: Nutrition / Diet Source Type: news

A Rare Adverse Effect Of Montelukast Treatment: Ecchymosis.
We report a rare case of a 31-year-old woman, with a history of allergic rhinitis and moderate persistent asthma, who experienced severe bruising on her lower extremities after starting montelukast treatment. Clinicians should be aware of the possibility of unusual bruising during montelukast therapy, and in those patients, treatment with montelukast should be discontinued. PMID: 23322887 [PubMed - as supplied by publisher] (Source: Respiratory Care)
Source: Respiratory Care - January 15, 2013 Category: Respiratory Medicine Authors: Aypak C, Türedi O, Solmaz N, Yikilkan H, Görpelioglu S Tags: Respir Care Source Type: research