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Hepatitis A virus (HAV) packaging size limitEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: HAV constructs containing insertions of approximately 500-600 nt but not 1,000 nt produced viable viruses, which indicated that the HAV particles can successfully package approximately 600 nt of additional sequences and maintain infectivity. (Source: Virology Journal)
Source: Virology Journal - November 18, 2009 Category: Virology Authors: Krishnamurthy KonduruSiham NakamuraGerardo Kaplan Source Type: journals

Hepatitis A vaccine/yellow fever vaccine: Autoimmune hepatitis: case reportEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Reactions)
Source: Reactions - November 16, 2009 Category: Drugs & Pharmacology Tags: Short communication Source Type: journals

ProQuadEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The Approval Letter and Approved Final Draft Labeling for Merck's Efficacy Supplement for Measles, Mumps, Rubella, and Varicella Vaccine, Live, (ProQuad®), to include concomitant administration with hepatitis A vaccine (VAQTA®) and/or pneumococcal conjugate vaccine (Prevnar®), use of ProQuad® in children 15 months to 12 years of age if a second dose of measles, mumps, rubella, and varicella is needed, additional safety data after a first or second dose of ProQuad®, and to comply with the Physician’s Labeling Rule format, have been issued. (Source: What's New at CBER)
Source: What's New at CBER - November 3, 2009 Category: Biomedical Science Source Type: organizations

Hepatitis A virus (HAV) proteinase 3C inhibits HAV IRES-dependent translation and cleaves the polypyrimidine tract-binding proteinEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Summary. Hepatitis A virus (HAV) infection is still an important issue worldwide. A distinct set of viruses encode proteins that enhance viral cap-independent translation initiation driven by an internal ribosome entry site (IRES) and suppress cap-dependent host translation. Unlike cytolytic picornaviruses, replication of HAV does not cause host cell shut off, and it has been questioned whether HAV proteins interfere with its own and/or host translation. HAV proteins were coexpressed in Huh-7 cells with reporter genes whose translation was initiated by either cap-dependent or cap-independent mechanisms. Among the proteins ...
Source: Journal of Viral Hepatitis - November 3, 2009 Category: Infectious Diseases Authors: T. Kanda, V. Gauss-Müller, S. Cordes, R. Tamura, K. Okitsu, W. Shuang, S. Nakamoto, K. Fujiwara, F. Imazeki, O. Yokosuka Source Type: journals

Epidemiology of hepatitis a virus infections, Germany, 2007-2008.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Approximately 60% of hepatitis A virus infections in Germany occur in persons without a travel history to disease-endemic areas and for whom sources of infection are unknown. Recommendation of pretravel vaccination fails to prevent the remaining imported infections. Using enhanced surveillance in 2007-2008, we analyzed epidemiologic patterns of hepatitis A in Germany and appropriateness and adequacy of current immunization recommendations. Young patients with a migration background who had visited friends and family in their ancestral countries accounted for most imported cases. Phylogenetic analysis showed high divers...
Source: Emerging Infectious Diseases - November 1, 2009 Category: Infectious Diseases Authors: Faber MS, Stark K, Behnke SC, Schreier E, Frank C Tags: Emerg Infect Dis Source Type: journals

Population seroprevalence of hepatitis E virus antibodies in rural Bangladesh.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Hepatitis E virus (HEV) causes a substantial burden of sporadic and epidemic disease worldwide. HEV infections result in serious morbidity and mortality, especially among pregnant women, and have significant economic costs. Few population-based studies have characterized the epidemiology of HEV. A rural Bangladeshi population was studied to determine the age- and gender- specific population seroprevalence of antibodies to HEV. Of 1,134 specimens tested from a representative, random population sample, 255 (22.5%) were anti-HEV IgG seropositive. Seroprevalence was lower among women (19.7%) than among men (25.8%). We foun...
Source: The American Journal of Tropical Medicine and Hygiene - October 31, 2009 Category: Tropical Medicine Authors: Labrique AB, Zaman K, Hossain Z, Saha P, Yunus M, Hossain A, Ticehurst J, Nelson KE Tags: Am J Trop Med Hyg Source Type: journals

Hepatitis E virus-based evaluation of a virion concentration method and detection of enteric viruses in environmental samples by multiplex nested RT-PCREmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: The study suggests absence of enteric viruses both in the source and in the purified water samples from Pune city, not allowing evaluation of the purification system and documents high prevalence of enteric viruses in river water, posing threat to the community.Significance and Impact of the Study: The rapid, sensitive and relatively inexpensive protocol developed for virological evaluation of water seems extremely useful and should be adapted for evaluating viral contamination of water for human consumption. This will lead to development of adequate control measures thereby reducing disease burden because of ...
Source: Journal of Applied Microbiology - October 30, 2009 Category: Microbiology Authors: V. Verma, V.A. Arankalle Source Type: journals

The interaction of hepatitis A virus (HAV) with soluble forms of its cellular receptor 1 (HAVCR1) share the physiological requirements of infectivity in cell culture.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: The interaction of HAV with soluble forms of HAVCR1 shares the temperature, Ca, and pH requirements for infectivity in cell culture and therefore mimics the cell entry process of HAV. Since soluble forms of HAVCR1 also neutralized wt HAV, this receptor may play a significant role in pathogenesis of HAV. (Source: Virology Journal)
Source: Virology Journal - October 27, 2009 Category: Virology Authors: Erica SilbersteinKrishnamurthy KonduruGerardo Kaplan Source Type: journals

What Problems Do I Need to Screen This New International Adoptee or Domestic Foster Care Child For?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Discussion There is much overlap between immigrant children and children in foster care - particularly around adoption. Immigrant children are defined as those who are legal and undocumented immigrants, refugees and international adoptees. Children in domestic foster care if not reunified with their parents may be adopted by relatives (kinship permanency) or with non-relatives (national adoptees). Additionally, international adoptees and children initially or recently placed into foster care need similar medical evaluations. Children that are adopted, including those who had been in foster care, have higher rates of asthm...
Source: PediatricEducation.org - October 26, 2009 Category: Pediatrics Authors: Donna M. D'Alessandro, M.D. Tags: Uncategorized Source Type: info

Viral Hepatitis A to E: An Update in 2010Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
ISBN: 978-3-8055-9344-1 (Source: Karger Publishers)
Source: Karger Publishers - October 24, 2009 Category: Databases & Libraries Source Type: info

Hepatitis B immunization coverage and risk behaviour among Danish travellers: Are immunization strategies based on single journey itineraries rational?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: The rationale and efficacy of current immunization strategies are challenged. Based on the results presented here and the availability of vaccines with long-lasting coverage, the authors find that recommendations of immunization should be based on lifetime risk instead of single journey itineraries. The authors find that a recommendation and/or cost-benefit discussion would be relevant in the pre-travel counselling of most – especially younger – travellers to endemic areas. (Source: Journal of Infection)
Source: Journal of Infection - October 23, 2009 Category: Infectious Diseases Authors: Ulla Schierup Nielsen, Eskild Petersen, Carsten Schade Larsen Tags: Original Articles Source Type: journals

Development of a Fluorescent in situ Method for Visualization of Enteric Viruses.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In this study, we report a fluorescent labeling strategy which was applied to murine norovirus (MNV-1), a human norovirus surrogate and hepatitis A virus (HAV). Specifically, streptavidin-labeled Quantum dots (Q-Dots) were bound to biotinylated capsids of MNV-1 and HAV (bio-MNV-1 and bio-HAV) which was confirmed using a sandwich- type approach in which streptavidin-bound plates were reacted with biotinylated virus followed by a secondary binding to Q-Dots 655. The assay demonstrated a relative fluorescence of 528 +/- 48.1 and 112 +/- 8.6 for bio-MNV-1 and control MNV-1, respectively. The biotinylation process did not impac...
Source: Applied and Environmental Microbiology - October 23, 2009 Category: Microbiology Authors: Rawsthorne H, Phister TG, Jaykus LA Tags: Appl Environ Microbiol Source Type: journals

Community-based cross-sectional seroprevalence study of hepatitis A in Bangladesh.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: The transition from high to intermediate HAV endemicity may be underway; high SES adolescents and adults remain particularly at risk of symptomatic illness. Preventive measures need consideration. PMID: 19842225 [PubMed - in process] (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - October 20, 2009 Category: Gastroenterology Authors: Saha SK, Saha S, Shakur S, Hanif M, Habib MA, Datta SK, Bock HL Tags: World J Gastroenterol Source Type: journals

Development and validation of a new questionnaire for the assessment of subjective physical performance in adult patients with haemophilia – the HEP-Test-QEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Summary. Specific research studies for the investigation of physical performance in haemophilic patients are rare. However, these instruments become increasingly more important to evaluate therapeutic treatments. Within the frame of the Haemophilia & Exercise Project (HEP), a new questionnaire, namely HEP-Test-Q, has been developed for the assessment of subjective physical performance in haemophilic adults. In this article, the development and validation of the HEP-Test-Q is described. The development consisted of different phases including item collection, pilot testing and field testing. The preliminary version was pilot...
Source: Haemophilia - October 20, 2009 Category: Hematology Authors: S. von MACKENSEN, D. CZEPA, M. HERBSLEB, T. HILBERG Source Type: journals

Current issues in the management of paediatric viral hepatitisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Viral hepatitis poses important problems for children. In preschoolers, hepatitis A virus (HAV) infection frequently causes acute liver failure. Vaccinating toddlers against HAV in countries with high endemicity is expected to decrease mortality. HAV vaccine demonstrates efficacy (comparable to immunoglobulin) as post-exposure prophylaxis. A recently developed vaccine against hepatitis E virus (HEV) may benefit fetal health, because pregnant women are most prone to acute liver failure as a result of HEV. Hepatitis B vaccine continues to demonstrate value and versatility for preventing serious liver disease. With chronic in...
Source: Liver International - October 18, 2009 Category: Gastroenterology Authors: Latifa T. F. Yeung, Eve A. Roberts Source Type: journals

Design, synthesis and preliminary antiviral screening of new N-phenylpyrazole and dihydroisoxazole derivativesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract A new series of N-phenylpyrazoles and dihydroisoxazles was synthesized starting from α,β-unsaturated ketones in basic media using phenyl hydrazine and hydroxylamine HCl, respectively. Antiviral evaluation of the target compounds revealed that the dihydroisoxazole derivatives have promising antiviral activity against hepatitis A virus and herpes simplex virus type 1. Content Type Journal ArticleCategory Original ResearchDOI 10.1007/s00044-009-9248-yAuthors Adel A. Rashad, Zagazig University Department of Medicinal Chemistry, Faculty of Pharmacy 44511 Zagazig EgyptOsama I. El-Sabbagh, Zagazig Uni...
Source: Medicinal Chemistry Research - October 14, 2009 Category: Chemistry Tags: Medicinal Chemistry Research Source Type: journals

Parvovirus B19-induced Thrombocytopenia and Anemia in a Child with Fatal Fulminant Hepatic Failure Coinfected with Hepatitis A and E VirusesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A 5-year-old male, drowsy, jaundiced child presented with fulminant hepatitis and had HAV and HEV infection. He had hepatic encephalopathy grade 1, fever, pallor, hypotension, crepitations in his right lung base and hepatosplenomegaly with dyspnoea. He had highly raised liver enzymes and hypoalbuminemia (2.8 g/dl) but anemia (hemoglobin of 7.7 g/dl and 5.7 g/dl 2 days later), reticulocytopenia and severe thrombocytopenia (44 x 109/l) were unexplained. Parvovirus B19-specific IgM antibodies and B19 DNA were found in the serum of the child. Chest X-ray showed pleural effusion and bronchopneumonia, while blood culture isolate...
Source: Journal of Tropical Pediatrics - October 12, 2009 Category: Tropical Medicine Authors: Kishore, J., Sen, M. Tags: Case Reports Source Type: journals

Clinical features of acute renal failure associated with hepatitis A virus infectionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Summary. Acute hepatitis A (AHA) is one of the most common infectious diseases; it is usually a self-limiting disease affecting the liver. Although extrahepatic manifestations are not common, some cases have been reported associated with acute renal failure. We reviewed the clinical features of patients with AHA complicated by acute renal failure (ARF group) and compared them with patients with noncomplicated AHA (non-ARF group). The medical records of 208 consecutive patients with AHA who were diagnosed between January 2003 and October 2008 were reviewed. We identified 15 patients (7.2%) with ARF associated with AHA. Ther...
Source: Journal of Viral Hepatitis - October 11, 2009 Category: Infectious Diseases Authors: Y. J. Jung, W. Kim, J. B. Jeong, B. G. Kim, K. L. Lee, K.-H. Oh, J.-H. Yoon, H.-S. Lee, Y. J. Kim Source Type: journals

Risk assessment in shellfish-borne outbreaks of hepatitis a.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
RISK ASSESSMENT IN SHELLFISH-BORNE OUTBREAKS OF HEPATITIS A. Appl Environ Microbiol. 2009 Oct 9; Authors: Pintó RM, Costafreda MI, Bosch A In the present work we aimed at determining the relationship between the hepatitis A virus (HAV) numbers in imported frozen coquina clams involved in two hepatitis outbreaks and the risk for human health. Due to HAV unculturability, an standardized TaqMan real-time RT-PCR controlling the virus/nucleic acid extraction and enzyme efficiencies was employed to figure the exposure dose for clams responsible for hepatitis cases. HAV numbers were then employed to figure the ri...
Source: Applied and Environmental Microbiology - October 8, 2009 Category: Microbiology Authors: Pintó RM, Costafreda MI, Bosch A Tags: Appl Environ Microbiol Source Type: journals

Treatment for early stage acute liver failureEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The antidote for acute liver failure caused by acetaminophen poisoning also can treat acute liver failure due to most other causes if given before severe injury occurs, UT Southwestern Medical Center scientists and their colleagues at 21 other institutions have found. Acute liver failure occurs when cells in the liver die quickly, resulting in toxins being released into the bloodstream and brain. Patients often end up in a hepatic coma as a result of toxins not being cleared by the failing liver. Known causes of acute liver failure include autoimmune hepatitis, drug-induced liver injury, hepatitis A and B, and acetaminophe...
Source: Medicineworld.org: New Article Alert - October 8, 2009 Category: Consumer Health News Source Type: info

[Stevens-Johnson syndrome plus intrahepatic cholestasis caused by clindamycin or chlorpheniramine]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We present a discussion of this case and review the main characteristics of the Stevens Johnson Syndrome. PMID: 19624990 [PubMed - indexed for MEDLINE] (Source: Dermatol Online J)
Source: Dermatol Online J - October 3, 2009 Category: Dermatology Authors: Sahagún Flores JE, Soto Ortiz JA, Tovar Méndez CE, Cárdenas Ochoa EC, Hernández Flores G Tags: Dermatol Online J Source Type: journals

Compliance with multiple-dose vaccine schedules among older children, adolescents, and adults: results from a vaccine safety datalink study.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: Compliance with multiple-dose vaccine series among older children, adolescents, and adults is suboptimal. Further evaluations of strategies to improve compliance in these populations are needed. PMID: 19797753 [PubMed - in process] (Source: American Journal of Public Health)
Source: American Journal of Public Health - September 30, 2009 Category: Global & Universal Authors: Nelson JC, Bittner RC, Bounds L, Zhao S, Baggs J, Donahue JG, Hambidge SJ, Jacobsen SJ, Klein NP, Naleway AL, Zangwill KM, Jackson LA Tags: Am J Public Health Source Type: journals

Natural course of fulminant hepatic failure: The scenario in Bangladesh and the differences from the westEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions:</b> The etiology of FHF in Bangladesh is different from that in the West. Prolongation of prothrombin time and occurrence of cerebral edema are predictors of the worst prognosis. (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - September 30, 2009 Category: Gastroenterology Authors: Alam Shahinul, Azam Golam, Mustafa Golam, Azad Abul Kalam, Haque Izazul, Gani Shakil, Ahmad Nooruddin, Alam Khorshed, Khan Mobin Source Type: journals

Acute acalculous cholecystitis revealing hepatitis A virus infection in childrenEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Arroud Mounir, Benmiloud Sara, Oudghiri Bouchra, Afifi My Abderrahmane, Hida Moustapha, Bouabdallah YoussefSaudi Journal of Gastroenterology 2009 15(4):277-277 (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - September 30, 2009 Category: Gastroenterology Authors: Arroud Mounir, Benmiloud Sara, Oudghiri Bouchra, Afifi My Abderrahmane, Hida Moustapha, Bouabdallah Youssef Source Type: journals

Wastewater workers and hepatitis A virus infectionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions This study shows that working in a wastewater treatment plant does not seem to be related to a greater prevalence of antibodies to hepatitis A. Moreover, the relative risk of HAV infection among WWs seems to be correlated with low anti-HAV(+) prevalence in the general population. (Source: Occupational Medicine)
Source: Occupational Medicine - September 24, 2009 Category: Respiratory Medicine Authors: Montuori, P., Negrone, M., Cacace, G., Triassi, M. Tags: Short Reports Source Type: journals

September 17, 2009 Approval Letter - HavrixEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Hepatitis A Vaccine, Inactivated, Havrix (Source: What's New at CBER)
Source: What's New at CBER - September 23, 2009 Category: Biomedical Science Source Type: organizations

September 16, 2009 Approval Letter - TwinrixEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Hepatitis A, Inactivated and Hepatitis B (Recombinant) Vaccine, Twinrix (Source: What's New at CBER)
Source: What's New at CBER - September 23, 2009 Category: Biomedical Science Source Type: organizations

CDC Revises Guidance on Hib and Hepatitis A Vaccination (CME/CE)Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Supplies are sufficient for clinicians to begin recalling children who deferred the booster dose of Haemophilus influenzae type b (Hib) conjugate vaccine, according to the CDC's Advisory Committee on Immunization Practices (ACIP). (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - September 18, 2009 Category: Gastroenterology Source Type: news

Hepatitis A Vaccine Recommended for Contacts of International AdopteesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - September 17, 2009 Category: Primary Care Tags: Medical News Source Type: info

Updated recommendations from the Advisory Committee on Immunization Practices (ACIP) for use of hepatitis A vaccine in close contacts of newly arriving international adoptees.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This report introduces the new recommendation and outlines the underlying epidemiologic and programmatic rationale. PMID: 19763077 [PubMed - indexed for MEDLINE] (Source: MMWR Morb Mortal Wkl...)
Source: MMWR Morb Mortal Wkl... - September 17, 2009 Category: Epidemiology Authors: , Tags: MMWR Morb Mortal Wkly Rep Source Type: journals

Updated Recommendations from the Advisory Committee on Immunization Practices (ACIP) for Use of Hepatitis A Vaccine in Close Contacts of Newly Arriving International AdopteesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: CDC Morbidity and Mortality Weekly Report)
Source: CDC Morbidity and Mortality Weekly Report - September 17, 2009 Category: American Health Source Type: organizations

Hepatitis A and B in CanadaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Hepatitis A and B are global liver diseases, and know no borders. While many may consider hepatitis A and B to be travel diseases, it is important to recognize that it can affect you right here at home, says Dr. Morris Sherman, Chairman of the Canadian Liver Foundation. (Source: Disabled World)
Source: Disabled World - September 16, 2009 Category: Disability Tags: Hepatitis Source Type: info

Duplex real time pcr for the detection of hepatitis a virus in shellfish using feline calicivirus as a process control.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In this study a duplex Real Time PCR method for quantitative detection of hepatitis A (HAV) in shellfish was developed. Feline calicivirus (FCV) was used as a control for assessing the effectiveness of the concentration and extraction process and the ability to eliminate PCR inhibitors present in the food matrix. The specific primers and probes for detection of HAV and FCV, chosen respectively from the 5'-UTR region and in the ORF1 region, were labeled with two different dyes and detected simultaneously. The method was applied on spiked and non spiked shellfish from a local market. The amplification of HAV in the presence ...
Source: Journal of Virological Methods - September 11, 2009 Category: Virology Authors: Di Pasquale S, Paniconi M, De Medici D, Suffredini E, Croci L Tags: J Virol Methods Source Type: journals

Virosomal Hepatitis A Vaccine: Comparing Intradermal and Subcutaneous With Intramuscular AdministrationEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions. The aluminum-free virosomal HAV vaccine Epaxal® is highly immunogenic and well tolerated when administered either via i.d., s.c., or i.m. Vaccination via the i.d. route may confer significant cost savings over the conventional i.m. route. (Source: Journal of Travel Medicine)
Source: Journal of Travel Medicine - September 10, 2009 Category: Infectious Diseases Authors: Gert Frösner, Robert Steffen, Christian Herzog Source Type: journals

Medical and Nursing Students with Suboptimal Protective Immunity against Vaccine‐Preventable Diseases • Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions. We have determined that there is a certain proportion of healthcare students who are susceptible to certain vaccine‐preventable diseases. The development of an appropriate vaccination strategy is required to decrease the risk of transmission in a hospital setting. (Source: Infect Control Hosp Epidemiol Latest Issue)
Source: Infect Control Hosp Epidemiol Latest Issue - September 10, 2009 Category: Epidemiology Tags: article Original Article Source Type: journals

Terrence Higgins Trust asks men in Coventry to come to the new MOT (Men Only Testing) CentreEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Terrence Higgins Trust (THT) is piloting a new testing service for gay men in Coventry. The charity is calling for men to come to the MOT Centre (Men Only Testing) for a free sexual health screening at its centre on 10 Manor Street. The pilot will take place on Tuesday 15th September between 5.30pm – 8pm.The service aims to provide an alternative testing environment for men in the city who might not be able to access traditional GUM services during the normal working day. THT will offer free and confidential testing for HIV, Hepatitis A and B, syphilis, chlamydia and gonorrhoea. The M.O.T Centre is drop in only, so there...
Source: Terrence Higgins Trust - September 9, 2009 Category: Infectious Diseases Source Type: organizations

Development of duck hepatitis A virus type 3 vaccine and its use to protect ducklings against infections.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In conclusion, we demonstrate that the live attenuated virus, AP-04203P100, is a promising vaccine candidate facilitating the prevention of duck hepatitis caused by DHAV-3 around East Asia including South Korea. PMID: 19747575 [PubMed - as supplied by publisher] (Source: Vaccine)
Source: Vaccine - September 7, 2009 Category: Allergy & Immunology Authors: Kim MC, Kim MJ, Kwon YK, Lindberg AM, Joh SJ, Kwon HM, Lee YJ, Kwon JH Tags: Vaccine Source Type: journals

Universal vaccination of children against hepatitis A in Chile - a cost-effectiveness studyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A structured abstract written by CRD reviewers. The abstract was published on 19 August 2009 from an original article published in 2008. (Source: Gastroenterology and Liver Diseases Specialist Library - Prevention)
Source: Gastroenterology and Liver Diseases Specialist Library - Prevention - September 5, 2009 Category: Gastroenterology Source Type: organizations

Universal vaccination of children against hepatitis A in Chile - a cost-effectiveness studyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A structured abstract written by CRD reviewers. The abstract was published on 19 August 2009 from an original article published in 2008. (Source: Gastroenterology and Liver Diseases Specialist Library - Liver)
Source: Gastroenterology and Liver Diseases Specialist Library - Liver - September 5, 2009 Category: Gastroenterology Source Type: organizations

Hepatitis AEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
— Comprehensive overview covers symptoms, treatment and prevention, including hepatitis A vaccine. Sponsored by:Chemotherapy.com - http://www.chemotherapy.com (Source: MayoClinic.com Full Feed)
Source: MayoClinic.com Full Feed - September 5, 2009 Category: Consumer Health News Source Type: news

Nested real-time PCR for hepatitis A detectionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: We have developed a novel NRT-PCR method capable of detecting as little as 0·2 PFU of HAV, which is significantly more sensitive than any other PCR technique tested in our system.Significance and Impact of the Study: NRT-PCR provides a potentially useful method for detecting HAV at extremely low levels, as frequently found in food samples, and can be potentially adopted as a regulatory method to ensure food safety. (Source: Letters in Applied Microbiology)
Source: Letters in Applied Microbiology - September 3, 2009 Category: Microbiology Authors: Y. Hu, I. Arsov Source Type: journals

[Original articles] High prevalence of autoantibodies in hepatitis A infection: the impact on laboratory profilesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: The study demonstrated a high prevalence of anticytoplasmic autoantibodies in patients with acute hepatitis A. These data would be useful to aid interpretation of indirect immunofluorescence testing in patients with acute hepatitis, especially in areas with a high prevalence of HAV. (Source: Journal of Clinical Pathology)
Source: Journal of Clinical Pathology - September 3, 2009 Category: Pathology Authors: Moon, H W, Noh, J K, Hur, M, Yun, Y M, Lee, C H, Kwon, S Y Tags: Liver disease, Immunology (including allergy), hepatitis And other GI infections, Hepatitis (sexual health) Original articles Source Type: journals

Guidelines for the Prevention and Treatment of Opportunistic Infections among HIV-exposed and HIV-infected children: recommendations from CDC, the National Institutes of Health, the HIV Medicine Association of the Infectious Diseases Society of America, the Pediatric Infectious Diseases Society, and the American Academy of Pediatrics.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This report updates and combines into one document earlier versions of guidelines for preventing and treating opportunistic infections (OIs) among HIV-exposed and HIV-infected children, last published in 2002 and 2004, respectively. These guidelines are intended for use by clinicians and other health-care workers providing medical care for HIV-exposed and HIV-infected children in the United States. The guidelines discuss opportunistic pathogens that occur in the United States and one that might be acquired during international travel (i.e., malaria). Topic areas covered for each OI include a brief description of the epidem...
Source: MMWR Recomm Rep - September 3, 2009 Category: Epidemiology Authors: Mofenson LM, Brady MT, Danner SP, Dominguez KL, Hazra R, Handelsman E, Havens P, Nesheim S, Read JS, Serchuck L, Van Dyke R, , , , , Tags: MMWR Recomm Rep Source Type: journals

Relationship among epidemiological parameters of six childhood infections in a non-immunized Brazilian community.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Epidemiological parameters, such as age-dependent force of infection and average age at infection (<IMG SRC='../img/13s1.gif' WIDTH=9 HEIGHT=12>) were estimated for rubella, varicella, rotavirus A, respiratory syncytial virus, hepatitis A and parvovirus B19 infections for a non-immunized Brazilian community, using the same sera samples. The for the aforementioned diseases were 8.45 years (yr) [95% CI: (7.23, 9.48) yr], 3.90 yr [95% CI: (3.51, 4.28) yr], 1.03 yr [95% CI: (0.96, 1.09) yr], 1.58 yr [95% CI: (1.39, 1.79) yr], 7.17 yr [95% CI: (6.48, 7.80) yr] and 7.43 yr [95% CI: (5.68, 9.59) yr], respectively. The d...
Source: Memorias do Instituto Oswaldo Cruz - September 1, 2009 Category: Infectious Diseases Authors: Amaku M, Azevedo RS, Castro RM, Massad E, Coutinho FA Tags: Mem Inst Oswaldo Cruz Source Type: journals

[Four patients with hepatitis A presenting with fulminant hepatitis and acute renal failure and who underwent liver transplantation.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report four cases of hepatitis A in which patients presented with fulminant hepatitis and acute renal failure and underwent liver transplantation. The following common features were observed in our cases: (1) occurrence in relatively old age (>/=39 years old), (2) association with acute renal failure, (3) presence of hepatomegaly, and (4) microscopic features of submassive hepatic necrosis. PMID: 19783886 [PubMed - in process] (Source: Korean J Hepatol)
Source: Korean J Hepatol - August 31, 2009 Category: Gastroenterology Authors: Oh SH, Lee JH, Hwang JW, Kim HY, Lee CH, Gwak GY, Choi MS, Koh KC, Paik SW, Yoo BC Tags: Korean J Hepatol Source Type: journals

HAVRIX (Hepatitis A Vaccine) Injection, Suspension [GlaxoSmithKline Biologicals SA]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Updated Date: Aug 31, 2009 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))
Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) - August 31, 2009 Category: Drugs & Pharmacology Source Type: organizations

Molecular epidemiology of hepatitis A virus in the South-East area of Gyeonggi-do in Korea.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: In these HAV sporadic cases, IIIA and IA were identified, and this may reflect co-circulation of various genotypes in Korea. This study provides valuable new data on the genetic distribution of HAV and important information to help design appropriate public health measures. PMID: 19718398 [PubMed - in process] (Source: Yonsei Medical Journal)
Source: Yonsei Medical Journal - August 30, 2009 Category: Universities & Medical Training Authors: Song HU, Hwang SG, Kwon CI, Lee JE, Ko KH, Hong SP, Park PW, Rim KS Tags: Yonsei Med J Source Type: journals

"Pseudotumoral" hepatic pattern in acute alcoholic hepatitis: a case report.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report a case of a patient affected by AAH with an unusual appearance of these "pseudotumoral" areas on CT scan, close resembling a metastatic cancer rather than a primary hepatocellular carcinoma. In fact, in contrast with previous reports, the picture was characterized by the presence of many inhomogeneous, hypoattenuated areas highlighted during both pre- and post-contrast phases. Moreover, we report the first description of "pseudotumoral" lesions on ultrasound scan. This patient was successfully treated with corticosteroids, even if many controversies still exist regarding their efficacy in this setting. PMID: ...
Source: World Journal of Gastroenterology : WJG - August 27, 2009 Category: Gastroenterology Authors: Tenca A, Massironi S, Colli A, Basilisco G, Conte D Tags: World J Gastroenterol Source Type: journals

MMWR Publishes Early Release of the Updated Guidelines for the Prevention and Treatment of Opportunistic Infection in HIV-Exposed and HIV-Infected ChildrenEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
“New guidelines to assist health care workers in preventing and treating the secondary infections that can afflict U.S. children exposed to, or infected with, HIV, were published by the National Institutes of Health and the Centers for Disease Control and Prevention.... “Major changes in the pediatric guidelines include: Emphasis on the importance of effective antiretroviral therapy to improve children’s immune function.… Information on diagnosing and managing immune reconstitution inflammatory syndrome…. Information on the management of antiretroviral therapy in children with opportunistic infections, in...
Source: AIDSinfo At-a-Glance: Offering Information on HIV/AIDS Treatment, Prevention, and Research, A Service of the U.S. Department of Health and Human Services (DHHS) - August 27, 2009 Category: Infectious Diseases Source Type: info

National, state, and local area vaccination coverage among children aged 19-35 months - United States, 2008.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This report describes the 2008 NIS coverage estimates for this series and individual vaccines, 7-valent pneumococcal conjugate vaccine (PCV7), >or=2 doses of hepatitis A vaccine (HepA), and hepatitis B vaccination received in the first 3 days of life (HepB birth dose) among children born during January 2005-June 2007. In 2008, 4:3:1:3:3:1 series coverage was 76.1%, compared with 77.4% in 2007; >or=90% coverage was maintained for all recommended series vaccines, except >or=4 doses of diphtheria, tetanus, and acellular pertussis (DTaP) vaccine. Coverage with >or=3 doses of Haemophilus influenzae type b vaccine (H...
Source: MMWR Morb Mortal Wkl... - August 27, 2009 Category: Epidemiology Tags: MMWR Morb Mortal Wkly Rep Source Type: journals