High Intensity Focused Ultrasound TherapyThis is an RSS file. You can use it to subscribe to this data in your favourite RSS reader, such as GoogleReader, or to display this data on your own website or blog. Subscribe to this data using MyMedWorm.Subscribe to this data using GoogleReader.Subscribe to this data using Bloglines.Subscribe to this data using MyYahoo.

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Imaging of prostate cancer local recurrences: why and how?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion These recent advances in imaging may improve the outcome of salvage therapies (by improving patient selection and treatment targeting) and should open the way to focal salvage treatments in the near future. Content Type Journal ArticleCategory UrogenitalDOI 10.1007/s00330-009-1647-4Authors Olivier Rouvière, Université de Lyon Lyon 69003 FranceThierry Vitry, Service d’imagerie urinaire et vasculaire Hospices Civils de Lyon, Hôpital Edouard Herriot Lyon 69003 FranceDenis Lyonnet, Université de Lyon Lyon 69003 France Journal European RadiologyOnline ISSN 1432-1084Print ISSN 0938-79...
Source: European Radiology - November 18, 2009 Category: Radiology Tags: European Radiology Source Type: journals

Salvage high-intensity focused ultrasound for biopsy-confirmed local recurrence of prostate cancer after radical prostatectomyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
To present experience in high-intensity focused ultrasound (HIFU) used as a salvage therapy for biopsy-confirmed local recurrence at the vesico-urethral anastomosis after radical prostatectomy (RP). From July 2006, four patients diagnosed with prostate cancer recurrence after RP were treated with HIFU, with or without salvage radiotherapy, using the Sonablate® 500 (Focus Surgery, IN, USA). Biochemical failure was defined as in increase in prostate-specific antigen (PSA) level of >0.2 ng/mL. No patients received any adjuvant therapy after HIFU therapy before reporting failure. The mean age and initial PSA level before RP w...
Source: BJU International - November 17, 2009 Category: Urology & Nephrology Authors: Akiko Murota-Kawano, Mayura Nakano, Sachiko Hongo, Sunao Shoji, Yoshihiro Nagata, Toyoaki Uchida Source Type: journals

USC prof to oversee HIFU trialEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Inderbir S. Gill, MD, professor and chairman of the department of urology at the Keck School of Medicine of the University of Southern California and founding director of the USC Institute of Urology, has been selected to oversee an FDA clinical trial of EDAP's high-intensity focused ultrasound (HIFU) system at various investigational sites in the U.S. (Source: Health Imaging News)
Source: Health Imaging News - November 16, 2009 Category: Radiology Tags: Latest News Source Type: news

EDAP Appoints Top U.S. Urologist to Lead FDA HIFU Clinical TrialEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
LYON, France, Nov. 16, 2009 (GLOBE NEWSWIRE) -- EDAP TMS SA (Nasdaq:EDAP), the global leader in therapeutic ultrasound, announced today that Dr. Inderbir S. Gill, professor and chairman of the Department of Urology at the Keck School of Medicine of the University of Southern California and founding director of the USC Institute of Urology will oversee the high-intensity focused ultrasound (HIFU) clinical trial being conducted at investigational sites in the United States. Dr. Gill, who began consulting with EDAP on March 15, 2009, will lead the current team of expert investigators and urologists participating in the trial....
Source: Medical News (via PRIMEZONE) - November 16, 2009 Category: Pharmaceuticals Source Type: news

High intensity focused ultrasound in the treatment of liver cancerEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A record from the CRD Health Techology Assessment Database. Published in July 2009. (Source: Gastroenterology and Liver Diseases Specialist Library - Liver)
Source: Gastroenterology and Liver Diseases Specialist Library - Liver - November 10, 2009 Category: Gastroenterology Source Type: organizations

Commentary on High-intensity focused ultrasound for prostate cancer: Comparative definitions of biochemical failure: Blana A, Brown SC, Chaussy C, Conti GN, Eastham JA, Ganzer R, Murat FJ, Pasticier G, Rebillard X, Rewcastle JC, Robertson CN, Thuroff S, Ward JF, Harlaching Hospital, Munich, GermanyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
To compare the specificity and sensitivity of different definitions of biochemical failure in patients treated with high-intensity focused ultrasound (HIFU) for prostate cancer, to identify the most accurate predictor of clinical failure after HIFU.Consecutively treated patients who underwent HIFU between October 1997 and July 2006 at two centers (Lyon, France, and Regensburg, Germany) were prospectively maintained within a central database and retrospectively reviewed for this study. Clinical failure was defined as a positive prostate biopsy after treatment, radiographic evidence of lymphatic or bony metastatic disease, o...
Source: Urologic Oncology: Seminars and Original Investigations - October 30, 2009 Category: Urology & Nephrology Authors: Joseph Smith Tags: Urologic Oncology Survey Source Type: journals

Biochemical Failure of High-Intensity Ultrasound for Prostate CA RedefinedEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
An increase in prostate-specific antigen (PSA) level of 1.2 ng/mL over the nadir should be considered a biochemical failure after high-intensity focused ultrasound for prostate cancer, according to authors of a paper in the October issue of BJU International. Reuters Health Information (Source: Medscape Urology Headlines)
Source: Medscape Urology Headlines - October 16, 2009 Category: Urology & Nephrology Tags: Urology Source Type: info

The dynamics of a non-equilibrium bubble near bio-materials.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In many medical treatments oscillating (non-equilibrium) bubbles appear. They can be the result of high-intensity-focused ultrasound, laser treatments or shock wave lithotripsy for example. The physics of such oscillating bubbles is often not very well understood. This is especially so if the bubbles are oscillating near (soft) bio-materials. It is well known that bubbles oscillating near (hard) materials have a tendency to form a high speed jet directed towards the material during the collapse phase of the bubble. It is equally well studied that bubbles near a free interface (air) tend to collapse with a jet directed ...
Source: Physics in Medicine and Biology - October 8, 2009 Category: Physics Authors: Ohl SW, Klaseboer E, Khoo BC Tags: Phys Med Biol Source Type: journals

Thermal ablation produced using a surgical toroidal high-intensity focused ultrasound device is independent from hepatic inflow occlusion.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In the liver, the efficacy of radiofrequency or high-intensity focused ultrasound (HIFU) ablation is impaired by blood perfusion. This can be overcome by hepatic inflow occlusion. Here we report the in vivo evaluation of ablations performed in the liver using a surgical toroidal HIFU device used during an open procedure with and without hepatic inflow occlusion. The HIFU device was composed of 256 toroidal-shaped emitters working at 3 MHz and an integrated ultrasound imaging probe working at 7.5 MHz. Using an intermittent Pringle maneuver (IPM), thermal ablations were created in three pigs with hepatic inflow occlusion...
Source: Physics in Medicine and Biology - October 8, 2009 Category: Physics Authors: Melodelima D, N'djin WA, Favre-Cabrera J, Parmentier H, Rivoire M, Chapelon JY Tags: Phys Med Biol Source Type: journals

EDAP to Participate in HIFU Liver Cancer TrialEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
LYON, France, Oct. 6, 2009 (GLOBE NEWSWIRE) -- EDAP TMS SA (Nasdaq:EDAP), the global leader in therapeutic ultrasound, announced today that the French regulatory organization AFSSAPS has authorized a Phase I clinical study to evaluate High Intensity Focused Ultrasound (HIFU) technology in patients with metastatic liver cancer. HIFU has the potential to assist with liver ablations and reduce bleeding during surgery. (Source: Medical News (via PRIMEZONE))
Source: Medical News (via PRIMEZONE) - October 6, 2009 Category: Pharmaceuticals Source Type: news

EDAP To Participate In HIFU Liver Cancer TrialEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
EDAP TMS SA, the global leader in therapeutic ultrasound, announced today that the French regulatory organization AFSSAPS has authorized a Phase I clinical study to evaluate High Intensity Focused Ultrasound (HIFU) technology in patients with metastatic liver cancer. HIFU has the potential to assist with liver ablations and reduce bleeding during surgery. (Source: Cancercompass News: Other Cancer)
Source: Cancercompass News: Other Cancer - October 6, 2009 Category: Cancer & Oncology Source Type: news

Localized Ablation of Thyroid Tissue by High-Intensity Focused Ultrasound: Improvement of Noninvasive Tissue Necrosis MethodsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Thyroid Oct 2009, Vol. 19, No. 10: 1085-1091. (Source: Thyroid)
Source: Thyroid - October 5, 2009 Category: Endocrinology Tags: article Source Type: journals

HIFU offers localized prostate cancer treatmentEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
High-intensity focused ultrasound of prostate cancer is less traumatic to healthy tissue than cryoablation, show results from an acute phase response study. (Source: MedWire News - Oncology)
Source: MedWire News - Oncology - September 28, 2009 Category: Cancer & Oncology Source Type: news

HIFU offers localized prostate cancer treatmentEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
High-intensity focused ultrasound of prostate cancer is less traumatic to healthy tissue than cryoablation, show results from an acute phase response study. (Source: MedWire News - Prostate Cancer)
Source: MedWire News - Prostate Cancer - September 28, 2009 Category: Cancer & Oncology Source Type: news

Philips, Celsion advance MR-guided HIFU collaborationEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Royal Philips Electronics and Celsion said that their joint research program to evaluate Celsion's heat-activated liposomal drug ThermoDox in combination with MR-guided high-intensity focused ultrasound (HIFU) as a combination therapy to non-invasively treat difficult cancers has successfully completed the feasibility stage. (Source: Health Imaging News)
Source: Health Imaging News - September 24, 2009 Category: Radiology Tags: Latest News Source Type: news

Pulmonary vein isolation with high-intensity focused ultrasound: results from the HIFU 12F studyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion The novel defocused 12F HIFU-BC used in conjunction with a steerable sheath allows for very rapid PVI in patients with PAF. The enthusiasm for rapid PVI is still dampened by the potential risk of collateral damage. (Source: Europace)
Source: Europace - September 23, 2009 Category: Cardiology Authors: Schmidt, B., Chun, K. R. J., Metzner, A., Fuernkranz, A., Ouyang, F., Kuck, K.-H. Tags: Ablation for Atrial Fibrillation Source Type: journals

EDAP Enhances Ablatherm-HIFU European Marketing StrategyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
LYON, France, Sept. 23, 2009 --(HSMN NewsFeed) -- EDAP TMS S.A. (Nasdaq:EDAP ), the global leader in therapeutic ultrasound, announced today the launch of an intensified communication and education strategy in France, aimed at increasing physician and pati... Devices, OncologyEDAP TMS, Ablatherm, high-intensity focused ultrasound, prostate cancer (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - September 23, 2009 Category: Pharmaceuticals Source Type: news

EDAP Enhances Ablatherm-HIFU European Marketing StrategyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
LYON, France, Sept. 23, 2009 (GLOBE NEWSWIRE) -- EDAP TMS S.A. (Nasdaq:EDAP), the global leader in therapeutic ultrasound, announced today the launch of an intensified communication and education strategy in France, aimed at increasing physician and patient awareness of Ablatherm-HIFU as a therapeutic option for localized prostate cancer. (Source: Medical News (via PRIMEZONE))
Source: Medical News (via PRIMEZONE) - September 23, 2009 Category: Pharmaceuticals Source Type: news

HIFU for prostate cancerEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Nature Reviews Clinical Oncology 6, 497 (2009). doi:10.1038/nrclinonc.2009.122 Author: Mandy Aujla (Source: Nature Clinical Practice Oncology)
Source: Nature Clinical Practice Oncology - September 22, 2009 Category: Cancer & Oncology Authors: Mandy Aujla Tags: Research Highlight Source Type: journals

Characterization of HIFU transducers designed for sonochemistry application: Cavitation distribution and quantification.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Acoustic field distribution was determined in HIFU sonoreactors as well as localization of cavitation activity by crossing different techniques: modeling, hydrophone measurements, laser tomography and SCL measurements. Particular care was taken with quantification of this last technique by pixels or photon counting. Cavitation bubbles generated by HIFU are mainly located on the outer layer of the propagation cone in the post-focal zone. Greatest acoustic activity is not located at the geometrical focal, but corresponds to a high concentration of bubbles zone. On the contrary, the main sonochemical activity shifts sligh...
Source: Ultrasonics - September 19, 2009 Category: Physics Authors: Hallez L, Touyeras F, Hihn JY, Klima J, Guey JL, Spajer M, Bailly Y Tags: Ultrasonics Source Type: journals

High-intensity focused ultrasound induced apoptosis with caspase 3, 8, and 9/6 activation in rat hepatomaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion HIFU-induced apoptosis in vivo and in vitro is one of the mechanisms for tumor control and is mediated by caspase 3, 8, and 9/6. The significantly greater activation of caspase 8 than of caspase 9/6 suggests that the apoptosis pathway induced by HIFU might be more mitochondria dependent than death receptor dependent. However, further examination will be needed. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s10396-009-0234-2Authors Naoki Hirokawa, Sapporo Medical University Department of Radiology, School of Medicine Minami-1, Nishi-16, Chuo-ku Sap...
Source: Journal of Medical Ultrasonics - September 15, 2009 Category: Radiology Tags: Journal of Medical Ultrasonics Source Type: journals

EDAP Successfully Expands HIFU Business and Approval in New TerritoriesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
LYON, France, Sept. 10, 2009 (GLOBE NEWSWIRE) -- EDAP TMS S.A. (Nasdaq:EDAP), the global leader in therapeutic ultrasound, announced today the expansion of Ablatherm-HIFU into new territories as part of the Company's global growth strategy: (Source: Medical News (via PRIMEZONE))
Source: Medical News (via PRIMEZONE) - September 10, 2009 Category: Pharmaceuticals Source Type: news

2009 Summer Forum for Present and Future of HIFU Treatment on Gynecological Diseases held in Chongqing, P.R. China (18-24 July 2009).Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19796979 [PubMed - as supplied by publisher] (Source: Ultrasonics Sonochemistry)
Source: Ultrasonics Sonochemistry - September 9, 2009 Category: Chemistry Authors: Wu J, Li F Tags: Ultrason Sonochem Source Type: journals

HIFU BasicsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
HIFU (High Intensity Focused Ultrasound) is a therapy option for BPH or prostate cancer (in some countries) that uses focused ultrasound waves to create intense heat at a specific site. Learn more about this prostate treatment option. (Source: About.com Prostate Cancer)
Source: About.com Prostate Cancer - September 1, 2009 Category: Cancer & Oncology Tags: health Source Type: consumer

High-intensity focused ultrasound with large scale spherical phased array for the ablation of deep tumors.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Under some circumstances surgical resection is feasible in a low percentage for the treatment of deep tumors. Nevertheless, high-intensity focused ultrasound (HIFU) is beginning to offer a potential noninvasive alternative to conventional therapies for the treatment of deep tumors. In our previous study, a large scale spherical HIFU-phased array was developed to ablate deep tumors. In the current study, taking into account the required focal depth and maximum acoustic power output, 90 identical circular PZT-8 elements (diameter=1.4 cm and frequency=1 MHz) were mounted on a spherical shell with a radius of curvature of ...
Source: J Zhejiang Univ Sci ... - August 31, 2009 Category: Science Authors: Ji X, Bai JF, Shen GF, Chen YZ Tags: J Zhejiang Univ Sci B Source Type: journals

High-intensity focused ultrasound shows acceptable recurrence-free rate in prostate cancerEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A single session of high-intensity focused ultrasound as primary therapy for localized prostate cancer results in an acceptable rate of biochemical-free recurrence. (Source: UrologyTimes - Prostate Cancer)
Source: UrologyTimes - Prostate Cancer - August 31, 2009 Category: Urology & Nephrology Source Type: journals

Studies: High-intensity focused ultrasound yields strong 5-year PSA-free survivalEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Two of several studies presented by the same international team suggest that high-intensity focused ultrasound provides good biochemical-free survival at 5 years in patients treated in the absence of hormone therapy. (Source: UrologyTimes - Prostate Cancer)
Source: UrologyTimes - Prostate Cancer - August 31, 2009 Category: Urology & Nephrology Source Type: journals

Dynamic Changes of Integrated Backscatter, Attenuation Coefficient and Bubble Activities During High-Intensity Focused Ultrasound (HIFU) TreatmentEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract: This paper simultaneously investigated the transient characteristics of integrated backscatter (IBS), attenuation coefficient and bubble activities as time traces before, during and after HIFU treatment, with different HIFU parameters (acoustic power and duty cycle) in both transparent tissue-mimicking phantoms and freshly excised bovine livers. These dynamic changes of acoustic parameters and bubble activities were correlated with the visualization of lesion development selected from photos, conventional B-mode ultrasound images and differential IBS images over the whole procedure of HIFU treatment. Two-dimensio...
Source: Ultrasound in Medicine and Biology - August 28, 2009 Category: Radiology Authors: Siyuan Zhang, Mingxi Wan, Hui Zhong, Cheng Xu, Zhenzhong Liao, Huanqing Liu, Supin Wang Tags: Original Contributions Source Type: journals

Minimally-invasive technologies in uro-oncology: The role of cryotherapy, HIFU and photodynamic therapy in whole gland and focal therapy of localised prostate cancerEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This article reviews the evidence for cryotherapy, high intensity focused ultrasound (HIFU) and photodynamic therapy in the treatment of localised prostate cancer. These ablative technologies can deliver a minimally invasive, day case treatment with effective early cancer control and low genitourinary morbidity. In addition, all have the ability to deliver focal therapy of only the malignant lesions within the prostate. (Source: Surgical Oncology)
Source: Surgical Oncology - August 27, 2009 Category: Surgery Authors: Hashim Uddin Ahmed, Caroline Moore, Mark Emberton Tags: Treatment Principles Source Type: journals

HIFU for prostate cancerEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Nature Reviews Clinical Oncology 6, 497 (2009). doi:10.1038/nrclinonc.2009.122 Author: Mandy Aujla (Source: Nature Clinical Practice Oncology)
Source: Nature Clinical Practice Oncology - August 26, 2009 Category: Cancer & Oncology Authors: Mandy Aujla Tags: Research Highlight Source Type: journals

Noninvasive Determination of in situ Heating Rate Using kHz Acoustic Emissions and Focused UltrasoundEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract: For high-intensity focused ultrasound (HIFU) to be widely applicable in the clinic, robust methods of treatment planning, guidance and delivery need to be developed. These technologies would greatly benefit if patient specific tissue parameters could be provided as inputs so that the treatment planning and monitoring schemes are customized and tailored on a case by case basis. A noninvasive method of estimating the local in situ acoustic heating rate using the heat transfer equation (HTE) and applying novel signal processing techniques is presented in this article. The heating rate is obtained by experimentally m...
Source: Ultrasound in Medicine and Biology - August 24, 2009 Category: Radiology Authors: Ajay Anand, Peter J. Kaczkowski Tags: Original Contributions Source Type: journals

EDAP Receives U.S. FDA 510(k) Approval for Sonolith I-SysEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Novel, Innovative and Robotized Next-Generation Lithotripsy Device to Enter U.S. Market LYON, France, Aug. 19, 2009 --(HSMN NewsFeed) -- EDAP TMS SA (Nasdaq:EDAP ), the global leader in therapeutic ultrasound, announced today that the U.S. Food and Drug... Devices, Urology, FDAEDAP TMS, Sonolith I-Sys, lithotripsy, high-intensity focused ultrasound (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - August 19, 2009 Category: Pharmaceuticals Source Type: news

US HIFU Announces Addition Of Tissue Change Monitoring (TCM) Software To Sonablate(R) 500 Medical DeviceEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
US HIFU, LLC, introduces a new software component, called Tissue Change Monitoring (TCM), to its Sonablate(R) 500 medical device that will enhance its existing minimally invasive treatment for prostate cancer using HIFU, high intensity focused ultrasound, by enabling physicians to monitor prostatic tissue changes in real-time. Stephen Puckett, Jr. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - August 19, 2009 Category: Consumer Health News Tags: Prostate / Prostate Cancer Source Type: news

Prostate cancer transrectal HIFU ablation: detection of local recurrences using T2-weighted and dynamic contrast-enhanced MRIEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The objective was to evaluate T2-weighted (T2w) and dynamic contrast-enhanced (DCE) MRI in detecting local cancer recurrences after prostate high-intensity focused ultrasound (HIFU) ablation. Fifty-nine patients with biochemical recurrence after prostate HIFU ablation underwent T2-weighted and DCE MRI before transrectal biopsy. For each patient, biopsies were performed by two operators: operator 1 (blinded to MR results) performed random and colour Doppler-guided biopsies (“routine biopsies”); operator 2 obtained up to three cores per suspicious lesion on MRI (“targeted biopsies”). Seventy-seven suspicious lesi...
Source: European Radiology - August 19, 2009 Category: Radiology Tags: European Radiology Source Type: journals

US HIFU Announces Addition of Tissue Change Monitoring (TCM) Software to Sonablate(R) 500 Medical DeviceEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CHARLOTTE, N.C., Aug. 18 (HSMN NewsFeed) -- US HIFU, LLC, introduces a new software component, called Tissue Change Monitoring (TCM), to its Sonablate® 500 medical device that will enhance its existing minimally invasive treatment for prostate cancer... Devices, OncologyUS HIFU, Tissue Change Monitoring, Sonablate 500, HIFU (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - August 19, 2009 Category: Pharmaceuticals Source Type: news

Safety and Efficacy of High Intensity Focused Ultrasound Ablation Therapy for AdenomyosisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: HIFU may be a safe and effective method to treat adenomyosis, and an acoustic intensity of 420 W may be able to produce larger volumes of necrosis and better pain relief. (Source: Academic Radiology)
Source: Academic Radiology - August 16, 2009 Category: Radiology Authors: Wei Wang, Yuexiang Wang, Jie Tang Tags: Original Investigations Source Type: journals

Prostate cancer treatment uses less-invasive ultrasoundEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Some men with prostate cancer are undergoing a new treatment to target cancer cells called high intensity focused ultrasound, which is less invasive than surgery or radiation. (Source: CBC | Health)
Source: CBC | Health - August 4, 2009 Category: Consumer Health News Source Type: news

Men with prostate cancer try less-invasive ultrasound procedureEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Some men with prostate cancer are undergoing a new treatment to target cancer cells called high intensity focused ultrasound, which is less invasive than surgery or radiation. (Source: CBC | Health)
Source: CBC | Health - August 4, 2009 Category: Consumer Health News Source Type: news

Making wavesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Nature Reviews Cancer 9, 530 (2009). doi:10.1038/nrc2711 Author: Sarah Seton-Rogers Sound waves could offer an alternative treatment for early-stage prostate cancer, with fewer side effects than the standard surgery or radiotherapy treatments.The trial, published in the British Journal of Cancer, treated 172 men in the United Kingdom with High Intensity Focused Ultrasound (HIFU), (Source: Nature Reviews Cancer)
Source: Nature Reviews Cancer - July 24, 2009 Category: Cancer & Oncology Authors: Sarah Seton-Rogers Tags: Research Highlight Source Type: journals

Low dimensional optimization for in vivo real-time porcine liver motion estimation using ultrasound imaging.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This study presents a contribution to the tracking of a moving target during high-intensity focused ultrasound (HIFU) treatment. Indeed, HIFU has proved to be highly efficient in inducing homogeneous and reproducible tumor destruction by thermal coagulation necrosis. However, accurate targeting of human abdominal tumors is difficult to maintain due to the motion induced by breathing. An algorithm is presented to track a region of interest of fixed size in a sequence of images. This algorithm was evaluated on synthetic data and on in vivo sequences of ultrasound liver images acquired using 12MHz ultrasound imaging probe at ...
Source: Ultrasonics - July 23, 2009 Category: Physics Authors: Fehrenbach J, Masmoudi M, Melodelima D Tags: Ultrasonics Source Type: journals

Simultaneous temperature and magnetization transfer (MT) monitoring during high-intensity focused ultrasound (HIFU) treatment: Preliminary investigation on ex vivo porcine muscleEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This study proposed an interleaved dual gradient-echo technique to monitor the heat and tissue damage brought to the heated tissue. The technique was applied to tissue samples to test its efficacy.Ex vivo experiments on the porcine muscle demonstrated that both temperature changes and MTR exhibited high consistency in localizing the heated regions. As the heat dissipated after the treatment, the temperature of the heated regions decreased rapidly but MTR continued to be elevated. Moreover, thermal dose (TD) maps derived from the temperature curves demonstrated a sharp margin in the heated regions, but MTR maps may show a s...
Source: Journal of Magnetic Resonance Imaging - July 22, 2009 Category: Radiology Authors: Hsu-Hsia Peng, Teng-Yi Huang, Wen-Yih Isaac Tseng, En-Li Lin, Hsiao-Wen Chung, Chih-Ching Wu, Yu-Shun Wang, Wen-Shiang Chen Source Type: journals

Investigations into Pulsed High-Intensity Focused Ultrasound–Enhanced Delivery: Preliminary Evidence for a Novel MechanismEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In this study, pulsed-HIFU exposures were given in the calf muscle of mice, followed by the administration of a variety of fluorophores, both soluble and particulate, by local or systemic injection. In vivo imaging (whole animal and microscopic) was used to quantify observations of increased extravasation and interstitial transport of the fluorophores as a result of the exposures. Histological analysis indicated that the exposures caused some structural alterations such as enlarged gaps between muscle fiber bundles. These effects were consistent with increasing the permeability of the tissues; however, they were found to ...
Source: Ultrasound in Medicine and Biology - July 20, 2009 Category: Radiology Authors: Hilary A. Hancock, Lauren H. Smith, Julian Cuesta, Amir K. Durrani, Mary Angstadt, Mark L. Palmeri, Eitan Kimmel, Victor Frenkel Tags: Original Contributions Source Type: journals

High-intensity ultrasound shows prostate cancer treatment promiseEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
High-intensity-focused ultrasound offers good short-term biochemical outcomes with few adverse effects in the treatment of localized prostate cancer, the results of a UK study indicate. (Source: MedWire News - Oncology)
Source: MedWire News - Oncology - July 7, 2009 Category: Cancer & Oncology Source Type: news

High-intensity ultrasound shows prostate cancer treatment promiseEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
High-intensity-focused ultrasound offers good short-term biochemical outcomes with few adverse effects in the treatment of localized prostate cancer, the results of a UK study indicate. (Source: MedWire News - Prostate Cancer)
Source: MedWire News - Prostate Cancer - July 6, 2009 Category: Cancer & Oncology Source Type: news

Ultrasound for prostate cancerEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
“A pioneering treatment for the UK's most common male cancer is more successful than surgery or radiotherapy,” The Daily Telegraph reported. The newspaper said that new research shows that intensive ultrasound therapy is as effective as traditional treatments (surgery or radiotherapy) but that side effects are dramatically reduced. This research found reasonably favourable results from high-intensity focused ultrasound (HIFU) treatment in 172 men with localised prostate cancer (cancer that had not spread). It also found that there were relatively low rates of urinary incontinence and erectile dysfunction following tre...
Source: NHS News Feed - July 2, 2009 Category: Consumer Health News Tags: Cancer Medical practice Source Type: news

Current salvage methods for recurrent prostate cancer after failure of primary radiotherapyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The objectives of this review were to analyse the eligibility criteria for careful selection of appropriate patients and to evaluate the oncological results and complications for each method. There are four whole-gland re-treatment options (salvage RP, salvage cryoablation, salvage brachytherapy, salvage HIFU) for RT failure, although others might be in development or investigations. Salvage RP has the longest follow-up with acceptable oncological results, but it is a challenging technique with a high complication rate. Salvage cryoablation is a feasible option, especially using third-generation technology, whereby the ave...
Source: BJU International - July 1, 2009 Category: Urology & Nephrology Authors: Masaki Kimura, Vladimir Mouraviev, Matvey Tsivian, Janice M. Mayes, Takefumi Satoh, Thomas J. Polascik Source Type: journals

Charity comments on new studyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The Prostate Cancer Charity comments on new study using HIFU to treat men with the disease (Source: The Prostate Cancer Charity)
Source: The Prostate Cancer Charity - June 30, 2009 Category: Cancer & Oncology Source Type: organizations