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This page shows you the latest news and research items in this category.

In vitro antibacterial activity and physicochemical properties of a crude methanol extract of the larvae of the blow fly Lucilia cuprina
Abstract The emergence of multidrug‐resistant bacterial strains has prompted the reintroduction of maggot therapy in the treatment of chronic, infected wounds. Many previous studies have demonstrated the potent antibacterial activity of larval excretions/secretions of the blowfly Lucilia sericata (Meigen) (Diptera:Calliphoridae) against bacteria. However, the antibacterial activity of its sibling species, Lucilia cuprina (Wiedemann) (Diptera:Calliphoridae) against a wide range of pathogenic bacteria has never been determined. The aim of this study was to develop a new procedure to produce whole body extract of larvae of ...
Source: Medical and Veterinary Entomology - May 8, 2013 Category: Veterinary Research Authors: C. H. TEH, W. A. NAZNI, H. L. LEE, A. FAIRUZ, S. B. TAN, M. SOFIAN‐AZIRUN Tags: Original Article Source Type: research

[Which alternatives are at our disposal in the anti-infectious therapeutics face to multi-drug resistant bacteria?].
Abstract The development of multi-drug resistance to antibiotics during the last years and the few number of new active molecules launched on the market have limited the treatment of some infectious diseases. Which alternatives are at our disposal in the anti-infectious therapeutics face to multi-drug resistant bacteria? Considering the bibliographic data, we can note different facts: (1) some alternatives already exist, but correspond more to targeted useful and usable therapeutics as phage therapy, honey therapy, or maggot therapy; (2) some "old" antibiotics can find new bacterial targets and reinforce the anti-i...
Source: Annales Pharmaceutiques Francaises - May 1, 2013 Category: Drugs & Pharmacology Authors: Bourlioux P Tags: Ann Pharm Fr Source Type: research

Patients' perceptions and experiences of venous leg ulceration and their attitudes to larval therapy: an in‐depth qualitative study
Discussion and conclusionsPatients may hold unrealistic expectations that larval therapy will effect a longed‐for cure for their leg ulcer(s) but an absence of healing may lead to feelings of disappointment or despair. (Source: Health Expectations)
Source: Health Expectations - February 15, 2013 Category: Health Management Authors: Dorothy McCaughan, Nicky Cullum, Joanne Dumville, Tags: Original Article Source Type: research

Maggot excretions affect the human complement system
This study indicates a CA‐reducing substrate that is already successfully used in clinical practice and may explain part of the improved wound healing caused by maggot therapy. Furthermore, the complement activation‐reducing substance present in maggot excretions could provide a novel treatment modality for several diseases, resulting from an (over)active complement system. (Source: Wound Repair and Regeneration)
Source: Wound Repair and Regeneration - October 30, 2012 Category: Surgery Authors: Gwendolyn Cazander, Marco W. J. Schreurs, Lennaert Renwarin, Corry Dorresteijn, Dörte Hamann, Gerrolt. N. Jukema Tags: Original Research‐Basic Science Source Type: research

The use of larval therapy to reduce the bacterial load in chronic wounds
Journal of Wound Care, Vol. 21, Iss. 5, 10 May 2012, pp 244 - 253 (Source: Contents for Journal of Wound Care, Volume 18 Issue 4 (26 March 2009))
Source: Contents for Journal of Wound Care, Volume 18 Issue 4 (26 March 2009) - May 9, 2012 Category: Nursing Authors: D. Blueman, C. Bousfield Source Type: research

Impact on wound healing and efficacy of various leg ulcer debridement techniques
Conclusions: Further studies are needed to strengthen the evidence for a significant impact of wound debridement on the healing of leg ulcers. (Source: JDDG)
Source: JDDG - May 1, 2012 Category: Dermatology Authors: Martin Doerler, Stefanie Reich‐Schupke, Peter Altmeyer, Markus Stücker Source Type: research

Maggot Therapy for Wound Debridement: A Randomized Multicenter Trial [Study]
Conclusions Although MDT shows no significant benefit at day 15 compared with conventional treatment, debridement by MDT is significantly faster and occurs during the first week of treatment. Because there is no benefit in continuing the treatment after 1 week, another type of dressing should be used after 2 or 3 applications of MDT. Trial Registration clinicaltrials.gov Identifier: NCT01211236 (Source: Archives of Dermatology)
Source: Archives of Dermatology - April 16, 2012 Category: Dermatology Authors: Opletalova, K., Blaizot, X., Mourgeon, B., Chene, Y., Creveuil, C., Combemale, P., Laplaud, A.-L., Sohyer-Lebreuilly, I., Dompmartin, A. Tags: Complementary and Alternative Medicine, Dermatology, Dermatologic Disorders, Randomized Controlled Trial, Comparative Effectiveness, Wound Healing, Dermatologic Procedures, Dermatologic Procedures, Other Study Source Type: research

Maggot therapy for repairing serious infective wound in a severely burned patient.
Abstract The larvae of musca domestica were put in use to discard the dead tissue of a case of severe burn. A total of 50 000 aseptic maggots were put onto the infective wound surface, and aseptic dressings overlaid the surface. Three days later, another 20 000 maggots were put onto the wound for the second therapy. After twice maggot debridement, most necrotic muscle tissues of the wound were cleaned up, and eventually fresh granulation tissue grew and later the wound was covered and healed by 3 times of skin grafting. The result demonstrates that maggot therapy is safe and effective with no adverse complications ...
Source: Chinese Journal of Traumatology - April 1, 2012 Category: Orthopaedics Authors: Wu JC, Lu RR, Huo R, Fu HB Tags: Chin J Traumatol Source Type: research

Maggot Therapy May Assist in Wound Healing
It sounds medieval, but it’s an accepted part of modern medicine: Maggots may assist in wound healing, French researchers report. (Source: WebMD Health)
Source: WebMD Health - December 19, 2011 Category: Consumer Health News Source Type: news

Maggot Therapy for Wound Debridement: A Randomized Multicenter Trial [Study]
Conclusions Although MDT shows no significant benefit at day 15 compared with conventional treatment, debridement by MDT is significantly faster and occurs during the first week of treatment. Because there is no benefit in continuing the treatment after 1 week, another type of dressing should be used after 2 or 3 applications of MDT. Trial Registration clinicaltrials.gov Identifier: NCT01211236 (Source: Archives of Dermatology)
Source: Archives of Dermatology - December 19, 2011 Category: Dermatology Authors: Opletalova, K., Blaizot, X., Mourgeon, B., Chene, Y., Creveuil, C., Combemale, P., Laplaud, A.-L., Sohyer-Lebreuilly, I., Dompmartin, A. Tags: Complementary and Alternative Medicine, Dermatology, Dermatologic Disorders, Randomized Controlled Trial, Comparative Effectiveness, Wound Healing, Dermatologic Procedures, Dermatologic Procedures, Other Study Source Type: research

What is a randomised controlled trial?
Introduction Randomised controlled trials (RCTs) answer questions about the effectiveness of different care options: ‘what effect does using treatment A or treatment B have on outcomes?’ RCTs are important to nursing as they are the best study design for answering the question ‘should I do this or that?’; nurses ask effectiveness questions frequently. Researchers refer to one treatment being tested as the ‘intervention’ (I) and another treatment (eg, one that would otherwise be used) as the ‘comparator’ (or control) (C). Examples of these effectiveness questions (as well as t...
Source: Evidence-Based Nursing - September 21, 2011 Category: Nursing Authors: Nelson, A. Tags: Immunology (including allergy), Child and adolescent psychiatry (paedatrics), Child health, Child and adolescent psychiatry, Drugs: musculoskeletal and joint diseases, Dermatology, Trauma, Diabetes, Metabolic disorders Research made simple Source Type: research

Glowing bandages 'could show infections'
Scientists are developing a “glowing bandage to treat infection”, The Guardian has today reported. The news is based on a new technique devised by researchers at the University of Sheffield, who are currently developing visual methods for quickly identifying the presence of bacteria that could infect a wound. Their technique involves using a long chain-shaped molecule (a polymer) bound to an antibiotic and to a fluorescent dye. In lab models of wounds the fluorescent dye would begin to glow under an ultraviolet (UV) lamp if the antibiotic bound to bacteria. This happens because, under these circumstances, the special p...
Source: NHS News Feed - September 16, 2011 Category: Consumer Health News Tags: Medication Medical practice Source Type: news

Hydrogel dressings for healing diabetic foot ulcers.
CONCLUSIONS: There is some evidence to suggest that hydrogel dressings are more effective in healing (lower grade) diabetic foot ulcers than basic wound contact dressings however this finding is uncertain due to risk of bias in the original studies. There is currently no research evidence to suggest that hydrogel is more effective than larval therapy or platelet-derived growth factors in healing diabetic foot ulcers, nor that one brand of hydrogel is more effective than another in ulcer healing. No RCTs comparing hydrogel dressings with other advanced dressing types were found. PMID: 21901730 [PubMed - in process] (Sou...
Source: Cochrane Database of Systematic Reviews - September 16, 2011 Category: Journals (General) Authors: Dumville JC, O'Meara S, Deshpande S, Speak K Tags: Cochrane Database Syst Rev Source Type: research

The use of larvae therapy to debride full thickness burns in the anaesthetically unfit patient: The Nottingham experience
Since antiquity the use of maggot or larval therapy has been well described in the management of chronic and necrotic wounds . Whilst the use of this modality dramatically declined after the 1940s with the revolutionary era of antibiotic therapy, there has been a rebirth in more recent years with the realisation that this modality can provide an effective solution to debride chronic wounds often contaminated with resistant organisms and especially in the anaesthetically compromised patient. (Source: Burns : Journal of the International Society for Burn Injuries)
Source: Burns : Journal of the International Society for Burn Injuries - June 2, 2011 Category: Cosmetic Surgery Authors: N. Akhtar, S. Abdel-Rehim, J. Rodrigues, P. Brooks Tags: Case Reports - E-only Source Type: research

Lucifensin, a Novel Insect Defensin of Medicinal Maggots: Synthesis and Structural Study.
Recently, we identified a new insect defensin, named lucifensin that is secreted/excreted by the blowfly Lucilia sericata larvae into a wound as a disinfectant during the medicinal process known as maggot therapy. Here, we report the total chemical synthesis of this peptide of 40 amino acid residues and three intramolecular disulfide bridges by using three different protocols. Oxidative folding of linear peptide yielded a peptide with a pattern of disulfide bridges identical to that of native lucifensin. The synthetic lucifensin was active against Gram-positive bacteria and was not hemolytic. We synthesized three lucif...
Source: Chembiochem - May 9, 2011 Category: Biochemistry Authors: Ceřovský V, Slaninová J, Fučík V, Monincová L, Bednárová L, Maloň P, Stokrová J Tags: Chembiochem Source Type: research

Maggot Therapy in Wound Management in Modern Era and a Review of Published Literature
Maggot therapy is an old remedy, which is being looked into with renewed interest. The use of medicinal maggots was approved by Food and Drug Administration (FDA) as a medical device in 2004. Maggot therapy appears to be efficacious, well tolerated, and cost-effective. Because American Medical Association (AMA) and Centers for Medicare and Medicaid (CMS) released reimbursement coding guidelines with regards to maggot therapy, there is a potential for a wider use of maggot therapy in United States in the near future. Several mechanisms of action suggested for maggots in debriding wounds are discussed. While maggot therapy d...
Source: Journal of Pharmacy Practice - March 8, 2011 Category: Drugs & Pharmacology Authors: Davydov, L. Tags: Review Articles Source Type: research

Maggots and their role in wound care.
Leg ulcers caused by chronic venous insufficiency affect a great many of the population, costing the NHS an estimated £200 million per year. The clinical use of sterile maggots under the brand name LarveE has increased steadily in the UK since they were introduced in the UK in late 1995. Maggot therapy breaks down necrotic tissue within a chronic wound, transforming it into an acute wound; subsequently beginning the healing process a lot quicker, thus reducing overall costs to the National Health Service. A literature review was conducted on studies that explored the use of maggot therapy in the management of chronic ...
Source: British Journal of Community Nursing - February 28, 2011 Category: Nursing Authors: Jones J, Green J, Lillie AK Tags: Br J Community Nurs Source Type: research

Maggot metabolites and their combinatory effects with antibiotic on Staphylococcus aureus
Conclusions: The combination effect of ES and ciprofloxacin at sub-MIC levels showed enhanced antibacterial activity compared to the effect of ES and ciprofloxacin as single agents. Based on the results of ES-ciprofloxacin combinations, a more effective means of treatment for S. aureus can be proposed. (Source: Annals of Clinical Microbiology and Antimicrobials)
Source: Annals of Clinical Microbiology and Antimicrobials - February 6, 2011 Category: Microbiology Authors: Shuchi AroraCarl BaptistaChu Sing Lim Source Type: research

Maggot microRNA: A new inhibitory pathway to bacterial infection
Summary: Refractory bacterial infectious diseases are clinically common and troublesome in the treatment. The traditional antibiotics could not be used to control bacterial infection with the indiscriminate use or abuse of drugs. Maggot therapy is a simple and highly successful method for healing of drug-resistant bacterial infected and necrotic wounds. It has been proved maggot can reduce the bacterial load within wounds effectively. However, the anti-bacterial mechanism of maggot is not clear. So far, most previous researches only focus on the anti-bacterial peptides from maggot, ignoring other possible anti-bacterial mo...
Source: Medical Hypotheses - October 31, 2010 Category: Biomedical Science Authors: Shouyu Wang, Zhen Zhang Tags: Articles Source Type: research

International Conference on Biotherapy to be held in the US
(Monarch Labs) The 8th International Conference on Biotherapy will be held in Los Angeles, Nov. 11-14, 2010, at the Universal - Los Angeles Hilton. Running concurrently, in the same conference center, will be the American Apitherapy Society's Annual Course and Conference. During the 4-day conference, an internationally distinguished faculty will educate clinicians and the public about maggot therapy, leech therapy, bee venom therapy, phage therapy, ichthyotherapy, helminthic therapy, pet and hippotherapy, cancer-detecting dogs and more. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - October 28, 2010 Category: Global & Universal Source Type: news

Efficient germ-line transformation of the economically important pest species Lucilia cuprina and Lucilia sericata (Diptera, Calliphoridae).
The green blowfly species L. cuprina and L. sericata are economically important pests for the sheep industries of Australia and New Zealand. L. cuprina has long been considered a good target for a genetic pest management program. In addition, L. sericata maggots are used in the cleaning of wounds and necrotic tissue of patients suffering from ulcers that are difficult to treat by other methods. Development of efficient transgenesis methods would greatly facilitate the development of strains ideal for genetic control programs or could potentially improve "maggot therapy". We have previously reported the germ-line transf...
Source: Insect Biochemistry and Molecular Biology - September 21, 2010 Category: Biochemistry Authors: Concha C, Belikoff EJ, Carey BL, Li F, Schiemann AH, Scott MJ Tags: Insect Biochem Mol Biol Source Type: research

Clean wounds by acting the maggot
Maggot therapy is used to treat a variety of conditions including pressure sores, surgical wounds and trauma injuries, writesJILL NESBITT (Source: The Irish Times - Health)
Source: The Irish Times - Health - August 23, 2010 Category: Consumer Health News Source Type: news

Clinical research on the bio‐debridement effect of maggot therapy for treatment of chronically infected lesions
Objective: (Source: Orthopaedic Surgery)
Source: Orthopaedic Surgery - July 31, 2010 Category: Orthopaedics Authors: Shou‐yu WangJiang‐ning WangDe‐cheng LvYun‐peng DiaoZhen Zhang Source Type: research

Clinical research on the bio-debridement effect of maggot therapy for treatment of chronically infected lesions
Conclusion: Maggot therapy is a safe and effective method for treating chronically infected lesions. (Source: Orthopaedic Surgery)
Source: Orthopaedic Surgery - July 20, 2010 Category: Orthopaedics Authors: Shou-yu Wang, Jiang-ning Wang, De-cheng Lv, Yun-peng Diao, Zhen Zhang Tags: ORIGINAL ARTICLES Source Type: research

Value of a modified clinical signs and symptoms of infection checklist for leg ulcer management.
CONCLUSION:: The modified Clinical Signs and Symptoms Checklist does not currently represent a valid tool to measure infection in leg ulcers. Some checklist items may predict bacterial load and may be better than subjective judgement alone. Copyright (c) 2010 British Journal of Surgery Society Ltd. Published by John Wiley & Sons, Ltd. PMID: 20309947 [PubMed - as supplied by publisher] (Source: The British Journal of Surgery)
Source: The British Journal of Surgery - March 21, 2010 Category: Surgery Authors: Dennis LA, Dumville JC, Cullum N, Bland JM Tags: Br J Surg Source Type: research

Value of a modified clinical signs and symptoms of infection checklist for leg ulcer management
The aim of this study was to analyse the validity of a modified Clinical Signs and Symptoms Checklist used to measure infection in a sample of patients with a leg ulcer.Data from patients recruited to a randomized controlled trial evaluating larval therapy (VenUS II) were analysed using factor analysis to identify the underlying checklist structure. Linear regression analysis identified whether checklist items, patient characteristics and subjective judgement of infection could predict bacterial load.There were several redundant checklist items when implemented in this sample and items forming the scale had low internal co...
Source: British Journal of Surgery - March 21, 2010 Category: Surgery Authors: L. A. Dennis, J. C. Dumville, N. Cullum, J. M. Bland Source Type: research

New interest in maggot therapy.
PMID: 20008505 [PubMed - as supplied by publisher] (Source: cmaj)
Source: cmaj - December 13, 2009 Category: Journals (General) Authors: Collier R Tags: CMAJ Source Type: research

Lucifensin, the long-sought antimicrobial factor of medicinal maggots of the blowfly Lucilia sericata.
A novel homologue of insect defensin designated lucifensin (Lucilia defensin) was purified from the extracts of various tissues (gut, salivary glands, fat body, haemolymph) of green bottle fly (Lucilia sericata) larvae and from their excretions/secretions. The primary sequence of this peptide of 40 residues and three intramolecular disulfide bridges was determined by ESI-QTOF mass spectrometry and Edman degradation and is very similar to that of sapecin and other dipteran defensins. We assume that lucifensin is the key antimicrobial component that protects the maggots when they are exposed to the highly infectious envi...
Source: Cellular and Molecular Life Sciences : CMLS - November 17, 2009 Category: Cytology Authors: Ceřovský V, Zďárek J, Fučík V, Monincová L, Voburka Z, Bém R Tags: Cell Mol Life Sci Source Type: research

Disruption of Staphylococcus epidermidis biofilms by medicinal maggot Lucilia sericata excretions/secretions.
Chronic infections are commonly associated with biofilms formed by bacteria such as Staphylococcus epidermidis. With the increase in antibiotic resistant bacteria, maggot debridement therapy has been reintroduced for the treatment of chronic wounds. Studies have shown that the excretion/ secretions (ES) of Lucilia sericata larvae (maggots) contain many bioactive compounds which may contribute to the efficacy of maggot therapy. The present study evaluates the effect of L. sericata ES on the formation and disruption of S. epidermidis 1457 and 5179-R1 biofilms. These strains employ either polysaccharide intercellular adhe...
Source: The International Journal of Artificial Organs - October 23, 2009 Category: Transplant Surgery Authors: Harris LG, Bexfield A, Nigam Y, Rohde H, Ratcliffe NA, Mack D Tags: Int J Artif Organs Source Type: research

Amino acid derivatives from Lucilia sericata excretions/secretions may contribute to the beneficial effects of maggot therapy via increased angiogenesis
Conclusions The demonstrated proliferative effect, selectively on endothelial cells, suggests that the amino acid-like compounds present in maggot ES may have a role in wound healing, by stimulating angiogenesis. (Source: British Journal of Dermatology)
Source: British Journal of Dermatology - October 2, 2009 Category: Dermatology Authors: A. Bexfield, A.E. Bond, C. Morgan, J. Wagstaff, R.P. Newton, N.A. Ratcliffe, E. Dudley, Y. Nigam Source Type: research

Maggot excretions/secretions induces human microvascular endothelial cell migration through AKT1.
Maggot therapy is a simple and highly successful method for healing of infected and necrotic wounds. The increasing evidences indicate that Maggot excretions/secretions (ES) plays important roles in the wounds healing process. But the precise molecular mechanisms remain undefined. Herein, we investigated if ES induced cell migration during wound healing process using microvascular endothelial cells (HMEC-1) as model, and this effect was associated with the activation of AKT1 and ERK1/2. Wound healing and transwell migration assays were performed to study the effects of ES on HMEC-1 cell migration. Our data showed that ...
Source: Molecular Biology Reports - September 15, 2009 Category: Molecular Biology Authors: Wang SY, Wang K, Xin Y, Lv DC Tags: Mol Biol Rep Source Type: research

Larval therapy as a palliative treatment for severe arteriosclerotic gangrene on the feet
We report a patient with ischaemia treated with LT. Inguinal revascularization was performed on a 69-year-old man with critical limb ischaemia, diabetes mellitus, heart failure and end-stage renal disease. Areas of dry black malodorous gangrene remained on the distal areas of the feet after surgery and the patient's poor health did not allow any additional surgery. The patient was referred to the dermatology department for LT. Although patients are usually given this treatment as inpatients, the patient requested treatment at home. After the first LT, there was a marked reduction in odour. The gangrene needed repeated appl...
Source: Clinical And Experimental Dermatology - July 2, 2009 Category: Dermatology Authors: A. Nordström, C. Hansson, L. Karlström Source Type: research

Larval therapy vs hydrogel for leg ulcers: similar benefits, costs
(Source: PharmacoEconomics and Outcomes News)
Source: PharmacoEconomics and Outcomes News - April 10, 2009 Category: Health Management Tags: Research article Source Type: research

Do maggots have an influence on bacterial growth? A study on the susceptibility of strains of six different bacterial species to maggots of Lucilia sericata and their excretions/secretions
Conclusion: There is no direct antibacterial effect of maggots and/or ES in vitro, however in clinical observations maggot therapy is successful. More research is needed to focus on possible indirect antibacterial activity, such as an immune-related effect. (Source: Journal of Tissue Viability)
Source: Journal of Tissue Viability - April 9, 2009 Category: Internal Medicine Authors: G. Cazander, K.E.B. van Veen, A.T. Bernards, G.N. Jukema Source Type: research

Larval therapy vs hydrogel for leg ulcers: similar benefits, costs.
Page: 7 (Source: PharmacoEconomics & Outcomes News)
Source: PharmacoEconomics & Outcomes News - April 7, 2009 Category: Drugs & Pharmacology Tags: HTML Source Type: research

Maggot Therapy Similar To Standard Care For Leg Ulcers
Larval (maggot) therapy has similar health benefits and costs compared with a standard treatment for leg ulcers, find two studies published on bmj.com today. Leg ulcers are chronic wounds most commonly caused by diseased veins in the legs. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - March 22, 2009 Category: Consumer Health News Tags: Dermatology Source Type: news

Maggot therapy similar to standard care for leg ulcers
Larval (maggot) therapy has similar health benefits and costs compared with a standard treatment for leg ulcers, find two studies (Source: Nursing in Practice)
Source: Nursing in Practice - March 21, 2009 Category: Nursing Source Type: news

Maggots No Better Than Gel For Wound Healing, Study
A UK study found that maggots (larval therapy) were no quicker at helping leg ulcers to heal or get rid of bacteria than the standard treatment based on hydrogel, and they were on the whole more painful, although they did speed up removal of dead tissue (debridement). (Source: Infectious Diseases / Bacteria / Viruses News From Medical News Today)
Source: Infectious Diseases / Bacteria / Viruses News From Medical News Today - March 20, 2009 Category: Infectious Diseases Tags: Infectious Diseases / Bacteria / Viruses Source Type: news

Maggot Therapy Comparable to Standard Care for Leg Ulcers
As a method of debridement for leg ulcers, treatment with maggots, also known as larval therapy, is generally comparable in effectiveness and costs to hydrogel dressings, according to the results of two studies conducted by the VenUS II research team. Reuters Health Information (Source: Medscape Pharmacist Headlines)
Source: Medscape Pharmacist Headlines - March 20, 2009 Category: Drugs & Pharmacology Tags: Dermatology Source Type: news

Maggot Therapy: No Advantage for Leg Ulcers
YORK, England (MedPage Today) -- For treating leg ulcers, maggot therapy was as effective as standard therapy with hydrogel, a randomized trial showed. (Source: MedPage Today Public Health)
Source: MedPage Today Public Health - March 20, 2009 Category: American Health Source Type: news

Health News of the Day
is a daily summary made from the selected links I post on Twitter. It is in a bullet points format with links to the original sources which include 350 RSS feeds that produce about 2,500 items per day.Meniscus tears increase knee osteoarthritis risk by 3-fold for minor tear and 8-fold for severe meniscal tear http://is.gd/o5fHLive maggot therapy is more painful and does not lead to faster healing of leg ulcers than standard treatment. http://is.gd/o6rsLarval therapy did not improve rate of healing of leg ulcers or reduce bacterial load compared with hydrogel, BMJ: http://is.gd/o6PwThe seemingly mild head injury that kille...
Source: Clinical Cases and Images - March 20, 2009 Category: Journals (General) Tags: Health News of the Day Source Type: news

Larval Debridement Therapy Effective for Leg Ulcers
In patients with sloughy or necrotic leg ulcers, debridement with larval therapy leads to similar outcomes at a similar cost as standard hydrogel therapy, but it may be associated with reduced time to debridement and more pain, according to two studies published March 19 in BMJ Online First. (Source: Modern Medicine)
Source: Modern Medicine - March 20, 2009 Category: Journals (General) Source Type: news

Maggots for Leg Ulcers? Maybe Not
Maggot therapy -- using live maggots to eat away dead tissue -- is more painful and does not lead to faster healing of leg ulcers than standard treatment, a study shows. (Source: WebMD Health)
Source: WebMD Health - March 19, 2009 Category: Consumer Health News Source Type: news

Maggot therapy hope 'premature'
Using maggots to treat leg ulcers is no better than standard treatment with a gel, a UK trial has found. (Source: BBC News | Health | UK Edition)
Source: BBC News | Health | UK Edition - March 19, 2009 Category: Consumer Health News Tags: Health Source Type: news

Monarch Labs announces first wound dressing in US specifically for maggot therapy
(Monarch Labs) Monarch Labs announced today the market launch of its new, proprietary wound dressing specifically designed to make maggot therapy more easy, quick and simple to administer. Monarch Labs has been allowed by the US Food and Drug Administration to produce and marketing this new wound care device under the trade name, LeFlap. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - March 10, 2009 Category: Infectious Diseases Source Type: news

An overview of maggot therapy used on chronic wounds in the community.
Maggot debridement therapy was re-introduced to clinical practice in the UK in the mid 1990s. While at first it was slow to be used by health care professionals, in recent times the therapy has enjoyed an upsurge in use, which has benefited both patients and the NHS. At the same time there has been some resistance to use from clinicians. This led to the introduction of a new presentation of maggots for use in wound care, which has proved popular with both patients and clinicians and has led to increasing use of maggot therapy for the treatment of chronic wounds. PMID: 19452661 [PubMed - in process] (Source: British...
Source: British Journal of Community Nursing - February 28, 2009 Category: Nursing Authors: Jones M Tags: Br J Community Nurs Source Type: research

Therapeutic applications of the larvae for wound debridement
Summary: It has been known for centuries that application of larvae is useful to heal certain wounds by facilitating debridement of necrotic tissue. Their therapeutic use was popularised in the beginning of the 19th century, but waned in the 1940s with the advent of antiseptic wound management and antibiotics. In more recent years, larvae are once again in vogue for management of difficult wounds.The mechanism of wound debridement by larvae includes the complete wound by continuous larval motion, secretion of proteolytic enzymes and antibacterial substances, effects on epidermal growth factor and interleukin-6 (IL-6) and i...
Source: Journal of Plastic, Reconstructive & Aesthetic Surgery - January 8, 2009 Category: Cosmetic Surgery Authors: Arif Turkmen, Ken Graham, D.A. McGrouther Tags: Invited Commentary Source Type: research

Maggot Therapy for Wound Management
No abstract available (Source: Advances in Skin & Wound Care)
Source: Advances in Skin & Wound Care - December 31, 2008 Category: Dermatology Tags: Departments: Research Forum Source Type: research

Maggot Therapy for Wound Management.
Page: 25DOI: 10.1097/01.ASW.0000343730.76308.6aAuthors: Hunter, Susan RN, MSN; Langemo, Diane PhD, RN, FAAN; Thompson, Patricia RN, MS; Hanson, Darlene RN, MS; Anderson, Julie PhD, RN, CCRC (Source: Advances in Skin & Wound Care)
Source: Advances in Skin & Wound Care - December 20, 2008 Category: Dermatology Tags: HTML PDF (165 K) Source Type: research