Integrating machine learning and nontargeted plasma lipidomics to explore lipid characteristics of premetabolic syndrome and metabolic syndrome
ConclusionIn the initial lipidomics analysis of pre-MetS and MetS, we identified relevant lipid features primarily linked to insulin resistance in key biochemical pathways. Biomarker panels composed of lipidomics components can reflect metabolic changes across different stages of MetS, offering valuable insights for the differential diagnosis of pre-MetS and MetS. (Source: Frontiers in Endocrinology)
Source: Frontiers in Endocrinology - March 15, 2024 Category: Endocrinology Source Type: research

Association of hyperuricemia with metabolic syndrome and its components in an adult population of Faisalabad, Pakistan
This study aims to determine the association of hyperuricemia with MetS and its individual components in a Pakistani cohort. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - March 15, 2024 Category: Nutrition Authors: Rameen Shahid, Misbah Hussain, Muhammad Umer Ghori, Ahmed Bilal, Fazli Rabbi Awan Tags: Research Paper Source Type: research

Genetic Links Between Metabolic Syndrome and Osteoarthritis: Insights from Cross-Trait Analysis
CONCLUSION: Our results illustrate a common genetic architecture, pleiotropic loci, as well as causality between MetS and OA, potentially enhancing our knowledge of high comorbidity and genetic processes that overlap between the two disorders.PMID:38482593 | DOI:10.1210/clinem/dgae169 (Source: The Journal of Clinical Endocrinology and Metabolism)
Source: The Journal of Clinical Endocrinology and Metabolism - March 14, 2024 Category: Endocrinology Authors: Ji-Xiang Huang Shu-Zhen Xu Tian Tian Jing Wang Ling-Qiong Jiang Tian He Shi-Yin Meng Jing Ni Hai-Feng Pan Source Type: research

Metabolic syndrome among apparently healthy adults residing in Delhi: Do vegetarian diets have a protective effect?
CONCLUSIONS: The study highlights a high prevalence of MetS among healthy urban adults residing in Delhi, India. The data, thus, show that a vegetarian diet did not have any protective impact against MetS, thus highlighting that it is important to consider the variations and quality of the vegetarian diets that negatively affect the body composition and contribute to the development of subsequent risk of developing MetS.PMID:38482298 | PMC:PMC10931883 | DOI:10.4103/jfmpc.jfmpc_340_23 (Source: Primary Care)
Source: Primary Care - March 14, 2024 Category: Primary Care Authors: Harmeet Kaur Bani Tamber Aeri Source Type: research

Genetic Links Between Metabolic Syndrome and Osteoarthritis: Insights from Cross-Trait Analysis
CONCLUSION: Our results illustrate a common genetic architecture, pleiotropic loci, as well as causality between MetS and OA, potentially enhancing our knowledge of high comorbidity and genetic processes that overlap between the two disorders.PMID:38482593 | DOI:10.1210/clinem/dgae169 (Source: The Journal of Clinical Endocrinology and Metabolism)
Source: The Journal of Clinical Endocrinology and Metabolism - March 14, 2024 Category: Endocrinology Authors: Ji-Xiang Huang Shu-Zhen Xu Tian Tian Jing Wang Ling-Qiong Jiang Tian He Shi-Yin Meng Jing Ni Hai-Feng Pan Source Type: research

Clinical and physiological advances in sedentary behavior research
Sedentary behavior, defined as sitting with low energy expenditure, has emerged as a modifiable risk factor that affects our physiology and health. Evidence for the detrimental effects of sedentary behavior/physical inactivity on health, however, stems largely from epidemiological studies, which cannot address causalities. Acute and short-term sedentary behavior reduction interventions have been performed; however, in these studies, sitting has often been replaced by formal physical activity options, such as exercise, and long-term studies in subjects with cardiometabolic risk factors are still relatively few. We have rece...
Source: Frontiers in Physiology - March 14, 2024 Category: Physiology Source Type: research

The regulatory role of m6A methylation modification in metabolic syndrome pathogenesis and progression
This study summarizes the m6A methylation regulators and their roles in metabolic syndrome development, highlighting the potential of m6A modification as a biomarker in metabolic disorders. (Source: Frontiers in Physiology)
Source: Frontiers in Physiology - March 14, 2024 Category: Physiology Source Type: research

Molecules, Vol. 29, Pages 1294: Unraveling Light-Activated Insulin Action in Regulating Blood Glucose: New Photoactivatable Insight as a Novel Modality in Diabetes Management
This study represents a pioneering introduction to this novel modality for diabetes management. (Source: Molecules)
Source: Molecules - March 14, 2024 Category: Chemistry Authors: Fahrul Nurkolis Rudy Kurniawan Elvan Wiyarta Rony Abdi Syahputra Reggie Surya Nurpudji Astuti Taslim Trina Ekawati Tallei Raymond Rubianto Tjandrawinata Eli Y. Adashi Bonglee Kim Tags: Perspective Source Type: research

Predictive effect of triglyceride-glucose index on No-Reflow Phenomenon in patients with type 2 diabetes mellitus and acute myocardial infarction undergoing primary percutaneous coronary intervention
Triglyceride glucose (TyG) index is considered as a new alternative marker of insulin resistance and a clinical predictor of type 2 diabetes mellitus (T2DM) combined with coronary artery disease. However, the ... (Source: Diabetology and Metabolic Syndrome)
Source: Diabetology and Metabolic Syndrome - March 14, 2024 Category: Endocrinology Authors: Juan Ma, Mohan Wang, Peng Wu, Xueping Ma, Dapeng Chen, Shaobin Jia and Ning Yan Tags: Research Source Type: research

Epicardial Adipose Tissue: A Precise Biomarker for Cardiovascular Risk, Metabolic Diseases, and Target for Therapeutic Interventions
Cardiol Rev. 2024 Mar 13. doi: 10.1097/CRD.0000000000000670. Online ahead of print.ABSTRACTEpicardial adipose tissue (EAT) is located between the heart muscle and visceral pericardium, where it has direct contact with coronary blood vessels. Elevated thickness of this tissue can induce local inflammation affecting the myocardium and the underlying coronary arteries, contributing to various cardiovascular diseases such as coronary artery disease, atrial fibrillation, or heart failure with preserved ejection fraction. Recent studies have identified EAT thickness as a simple and reliable biomarker for certain cardiovascular o...
Source: Atherosclerosis - March 13, 2024 Category: Cardiology Authors: Aleksander Bogda ński Piotr Nizio łek Stanis ław Kopeć Ma łgorzata Moszak Source Type: research

Biomolecular Actions by Intestinal Endotoxemia in Metabolic Syndrome
In this study, we seek to provide a description of the knowledge to date of the IM and its metabolome and the factors that influence it. Furthermore, we analyze the interactions between the functions of the IM and the pathophysiology of major metabolic diseases via local and systemic metabolome's relate endotoxemia.PMID:38474087 | DOI:10.3390/ijms25052841 (Source: Atherosclerosis)
Source: Atherosclerosis - March 13, 2024 Category: Cardiology Authors: Ioannis Alexandros Charitos Maria Aliani Pasquale Tondo Maria Venneri Giorgio Castellana Giulia Scioscia Francesca Castellaneta Donato Lacedonia Mauro Carone Source Type: research

Epicardial Adipose Tissue: A Precise Biomarker for Cardiovascular Risk, Metabolic Diseases, and Target for Therapeutic Interventions
Cardiol Rev. 2024 Mar 13. doi: 10.1097/CRD.0000000000000670. Online ahead of print.ABSTRACTEpicardial adipose tissue (EAT) is located between the heart muscle and visceral pericardium, where it has direct contact with coronary blood vessels. Elevated thickness of this tissue can induce local inflammation affecting the myocardium and the underlying coronary arteries, contributing to various cardiovascular diseases such as coronary artery disease, atrial fibrillation, or heart failure with preserved ejection fraction. Recent studies have identified EAT thickness as a simple and reliable biomarker for certain cardiovascular o...
Source: Atherosclerosis - March 13, 2024 Category: Cardiology Authors: Aleksander Bogda ński Piotr Nizio łek Stanis ław Kopeć Ma łgorzata Moszak Source Type: research

Biomolecular Actions by Intestinal Endotoxemia in Metabolic Syndrome
In this study, we seek to provide a description of the knowledge to date of the IM and its metabolome and the factors that influence it. Furthermore, we analyze the interactions between the functions of the IM and the pathophysiology of major metabolic diseases via local and systemic metabolome's relate endotoxemia.PMID:38474087 | PMC:PMC10931779 | DOI:10.3390/ijms25052841 (Source: Atherosclerosis)
Source: Atherosclerosis - March 13, 2024 Category: Cardiology Authors: Ioannis Alexandros Charitos Maria Aliani Pasquale Tondo Maria Venneri Giorgio Castellana Giulia Scioscia Francesca Castellaneta Donato Lacedonia Mauro Carone Source Type: research

Missed Diagnosis of Gestational Diabetes Mellitus Due to Selective Screening: Evidence from a Cross-Sectional Study in the West Nile Sub-Region, Uganda
(Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy)
Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy - March 13, 2024 Category: Endocrinology Tags: Diabetes, Metabolic Syndrome and Obesity Source Type: research

Assessment of Changes in Body Composition After 3 Months of Dulaglutide Treatment
(Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy)
Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy - March 13, 2024 Category: Endocrinology Tags: Diabetes, Metabolic Syndrome and Obesity Source Type: research