Biological Therapy for Psoriasis in Cancer Patients: An 8-Year Retrospective Real-Life Study
Conclusions: Our experience supports the effectiveness and safety of biological therapy for psoriasis in patients with a history of cancer or recent onset neoplasia.PMID:38610706 | DOI:10.3390/jcm13071940 (Source: Clinical Breast Cancer)
Source: Clinical Breast Cancer - April 13, 2024 Category: Cancer & Oncology Authors: Teresa Battista Lucia Gallo Fabrizio Martora Davide Fattore Luca Potestio Sara Cacciapuoti Massimiliano Scalvenzi Matteo Megna Source Type: research
Biological Therapy for Psoriasis in Cancer Patients: An 8-Year Retrospective Real-Life Study
Conclusions: Our experience supports the effectiveness and safety of biological therapy for psoriasis in patients with a history of cancer or recent onset neoplasia.PMID:38610706 | DOI:10.3390/jcm13071940 (Source: Clinical Genitourinary Cancer)
Source: Clinical Genitourinary Cancer - April 13, 2024 Category: Cancer & Oncology Authors: Teresa Battista Lucia Gallo Fabrizio Martora Davide Fattore Luca Potestio Sara Cacciapuoti Massimiliano Scalvenzi Matteo Megna Source Type: research
The Cancer-Protective Potential of Protocatechuic Acid: A Narrative Review
Molecules. 2024 Mar 23;29(7):1439. doi: 10.3390/molecules29071439.ABSTRACTCancer is one of the leading causes of death worldwide, making the search for alternatives for its control a critical issue. In this context, exploring alternatives from natural sources, such as certain vegetables containing a variety of secondary metabolites with beneficial effects on the body and that play a crucial role in the fight against cancer, is essential. Among the compounds with the greatest efficacy in controlling this disease, those with antioxidant activity, particularly phenolic com-pounds, stand out. A remarkable example of this group...
Source: Cancer Control - April 13, 2024 Category: Cancer & Oncology Authors: Jorge Cadena-I ñiguez Edelmiro Santiago-Osorio Nancy S ánchez-Flores Sandra Salazar-Aguilar Ram ón Marcos Soto-Hernández Mar ía de la Luz Riviello-Flores V íctor Manuel Macías-Zaragoza Itzen Agui ñiga-Sánchez Source Type: research
Biological markers of adipose tissue: Adipokines
Ann Endocrinol (Paris). 2024 Apr 16:S0003-4266(24)00050-7. doi: 10.1016/j.ando.2024.04.002. Online ahead of print.ABSTRACTWe currently have a large sum of clinical and experimental data documenting the involvement of numerous adipokines in the maintenance of energy homeostasis in healthy individuals and their dysregulation in diseases such as obesity, metabolic syndrome or type 2 diabetes. Despite the impressive discoveries made in this field over many years, much remains to be done before understanding all the physiological and pathological implications, and hoping for the development of other effective and safe therapeut...
Source: Annales d'Endocrinologie - April 13, 2024 Category: Endocrinology Authors: Jean-Philippe Bastard Imane Dridi-Brahimi Camille Vatier Soraya Fellahi Bruno F ève Source Type: research
Fractional Excretion of Urate is Positively Associated with Type 2 Diabetes in HUA Patients: A Cross-Sectional Study
(Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy)
Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy - April 13, 2024 Category: Endocrinology Tags: Diabetes, Metabolic Syndrome and Obesity Source Type: research
Metabolic effects of testosterone added to intensive lifestyle intervention in older men with obesity and hypogonadism
CONCLUSION: In older men with obesity and hypogonadism, adding TRT for six months to LT does not result in further improved cardiometabolic profiles, and could potentially blunt some of the metabolic benefits induced by LT.PMID:38606934 | DOI:10.1210/clinem/dgae249 (Source: The Journal of Clinical Endocrinology and Metabolism)
Source: The Journal of Clinical Endocrinology and Metabolism - April 12, 2024 Category: Endocrinology Authors: Adrian M Gonzalez-Gil Yoann Barnouin Alessandra Celli Viola Viola Marcos D Villarreal Maria Liza Duremdes Nava Adam Sciuk Clifford Qualls Reina Armamento-Villareal Dennis T Villareal Source Type: research
Depression, Anxiety, and Risk of Metabolic Syndrome in Women With Polycystic Ovary Syndrome: A Longitudinal Study
CONCLUSIONS: Patients with PCOS and depression and/or anxiety have a high risk of developing MetSyn, with a stronger association between depression and MetSyn. Our findings highlight the urgent need for guideline-directed screening for depression and anxiety at time of diagnosis of PCOS as well as screening at subsequent visits to facilitate risk stratification for metabolic monitoring and early intervention in this high-risk group.PMID:38609160 | DOI:10.1210/clinem/dgae256 (Source: The Journal of Clinical Endocrinology and Metabolism)
Source: The Journal of Clinical Endocrinology and Metabolism - April 12, 2024 Category: Endocrinology Authors: Iris T Lee John Rees Shakira King Anne Kim Tess Cherlin Stefanie Hinkle Sunni L Mumford Anuja Dokras Source Type: research
Molecular and pathophysiological relationship between obesity and chronic inflammation in the manifestation of metabolic dysfunctions and their inflammation ‑mediating treatment options (Review)
Mol Med Rep. 2024 Jun;29(6):95. doi: 10.3892/mmr.2024.13219. Epub 2024 Apr 12.ABSTRACTObesity reaches up to epidemic proportions globally and increases the risk for a wide spectrum of co‑morbidities, including type‑2 diabetes mellitus (T2DM), hypertension, dyslipidemia, cardiovascular diseases, non‑alcoholic fatty liver disease, kidney diseases, respiratory disorders, sleep apnea, musculoskeletal disorders and osteoarthritis, subfertility, psychosocial problems and certain types of cancers. The underlying inflammatory mechanisms interconnecting obesity with metabolic dysfunction are not completely understood. Increas...
Source: Molecular Medicine - April 12, 2024 Category: Molecular Biology Authors: Fani-Niki Varra Michail Varras Viktoria-Konstantina Varra Panagiotis Theodosis-Nobelos Source Type: research
Molecular and pathophysiological relationship between obesity and chronic inflammation in the manifestation of metabolic dysfunctions and their inflammation ‑mediating treatment options (Review)
Mol Med Rep. 2024 Jun;29(6):95. doi: 10.3892/mmr.2024.13219. Epub 2024 Apr 12.ABSTRACTObesity reaches up to epidemic proportions globally and increases the risk for a wide spectrum of co‑morbidities, including type‑2 diabetes mellitus (T2DM), hypertension, dyslipidemia, cardiovascular diseases, non‑alcoholic fatty liver disease, kidney diseases, respiratory disorders, sleep apnea, musculoskeletal disorders and osteoarthritis, subfertility, psychosocial problems and certain types of cancers. The underlying inflammatory mechanisms interconnecting obesity with metabolic dysfunction are not completely understood. Increas...
Source: Molecular Medicine Reports - April 12, 2024 Category: Molecular Biology Authors: Fani-Niki Varra Michail Varras Viktoria-Konstantina Varra Panagiotis Theodosis-Nobelos Source Type: research
Molecular and pathophysiological relationship between obesity and chronic inflammation in the manifestation of metabolic dysfunctions and their inflammation ‑mediating treatment options (Review)
Mol Med Rep. 2024 Jun;29(6):95. doi: 10.3892/mmr.2024.13219. Epub 2024 Apr 12.ABSTRACTObesity reaches up to epidemic proportions globally and increases the risk for a wide spectrum of co‑morbidities, including type‑2 diabetes mellitus (T2DM), hypertension, dyslipidemia, cardiovascular diseases, non‑alcoholic fatty liver disease, kidney diseases, respiratory disorders, sleep apnea, musculoskeletal disorders and osteoarthritis, subfertility, psychosocial problems and certain types of cancers. The underlying inflammatory mechanisms interconnecting obesity with metabolic dysfunction are not completely understood. Increas...
Source: Molecular Medicine Reports - April 12, 2024 Category: Molecular Biology Authors: Fani-Niki Varra Michail Varras Viktoria-Konstantina Varra Panagiotis Theodosis-Nobelos Source Type: research
Impact of diabetes mellitus on osteoarthritis: a scoping review on biomarkers
Expert Rev Mol Med. 2024 Apr 12;26:e8. doi: 10.1017/erm.2024.7.ABSTRACTOsteoarthritis (OA) commonly affects the knee and hip joints and accounts for 19.3% of disability-adjusted life years and years lived with disability worldwide (Refs , ). Early management is important in order to avoid disability uphold quality of life (Ref. ). However, a lack of awareness of subclinical and early symptomatic stages of OA often hampers early management (Ref. ). Moreover, late diagnosis of OA among those with severe disease, at a stage when OA management becomes more complicated is common (Refs , , , ). Established risk factors for the d...
Source: Molecular Medicine - April 12, 2024 Category: Molecular Biology Authors: Shi Rui Seow Sumaiyah Mat Amalina Ahmad Azam Nor Fadilah Rajab Intan Safinar Ismail Devinder Kaur Ajit Singh Suzana Shahar Maw Pin Tan Francis Berenbaum Source Type: research
Molecular and pathophysiological relationship between obesity and chronic inflammation in the manifestation of metabolic dysfunctions and their inflammation ‑mediating treatment options (Review)
Mol Med Rep. 2024 Jun;29(6):95. doi: 10.3892/mmr.2024.13219. Epub 2024 Apr 12.ABSTRACTObesity reaches up to epidemic proportions globally and increases the risk for a wide spectrum of co‑morbidities, including type‑2 diabetes mellitus (T2DM), hypertension, dyslipidemia, cardiovascular diseases, non‑alcoholic fatty liver disease, kidney diseases, respiratory disorders, sleep apnea, musculoskeletal disorders and osteoarthritis, subfertility, psychosocial problems and certain types of cancers. The underlying inflammatory mechanisms interconnecting obesity with metabolic dysfunction are not completely understood. Increas...
Source: Molecular Medicine - April 12, 2024 Category: Molecular Biology Authors: Fani-Niki Varra Michail Varras Viktoria-Konstantina Varra Panagiotis Theodosis-Nobelos Source Type: research
Impact of diabetes mellitus on osteoarthritis: a scoping review on biomarkers
Expert Rev Mol Med. 2024 Apr 12;26:e8. doi: 10.1017/erm.2024.7.ABSTRACTOsteoarthritis (OA) commonly affects the knee and hip joints and accounts for 19.3% of disability-adjusted life years and years lived with disability worldwide (Refs , ). Early management is important in order to avoid disability uphold quality of life (Ref. ). However, a lack of awareness of subclinical and early symptomatic stages of OA often hampers early management (Ref. ). Moreover, late diagnosis of OA among those with severe disease, at a stage when OA management becomes more complicated is common (Refs , , , ). Established risk factors for the d...
Source: Molecular Medicine - April 12, 2024 Category: Molecular Biology Authors: Shi Rui Seow Sumaiyah Mat Amalina Ahmad Azam Nor Fadilah Rajab Intan Safinar Ismail Devinder Kaur Ajit Singh Suzana Shahar Maw Pin Tan Francis Berenbaum Source Type: research
Regulation of host metabolic health by parasitic helminths
Trends Parasitol. 2024 Apr 11:S1471-4922(24)00073-4. doi: 10.1016/j.pt.2024.03.006. Online ahead of print.ABSTRACTObesity is a worldwide pandemic and major risk factor for the development of metabolic syndrome (MetS) and type 2 diabetes (T2D). T2D requires lifelong medical support to limit complications and is defined by impaired glucose tolerance, insulin resistance (IR), and chronic low-level systemic inflammation initiating from adipose tissue. The current preventative strategies include a healthy diet, controlled physical activity, and medication targeting hyperglycemia, with underexplored underlying inflammation. Stud...
Source: Trends in Parasitology - April 12, 2024 Category: Parasitology Authors: Suchandan Sikder Doris Pierce Eti R Sarkar Connor McHugh Kate G R Quinlan Paul Giacomin Alex Loukas Source Type: research
Correlation between acne and insulin resistance; experience from central India
CONCLUSION: Our study suggests the prevalence of insulin resistance in 42.67% of patients with acne, thereby providing the possibility of use of insulin modifiers as an adjunct acne treatment and stratifying the possible risk of metabolic syndrome in patients with acne. Also recommended is the control of dietary factors and lifestyle modification for the management of acne with insulin resistance.PMID:38605790 | PMC:PMC11006054 | DOI:10.4103/jfmpc.jfmpc_1232_23 (Source: Primary Care)
Source: Primary Care - April 12, 2024 Category: Primary Care Authors: Prachi R Srivastava Jaideep Khare Animesh Saxena Sushil Jindal Source Type: research
