Jiawei Shengjiangsan ’s Effect on Renal Injury in Diabetic Nephropathy Mice is Investigated via the PI3K/Akt/NF-κB Signaling Pathway
(Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy)
Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy - April 11, 2024 Category: Endocrinology Tags: Diabetes, Metabolic Syndrome and Obesity Source Type: research
Would Combination Be Better: Swimming Exercise and Intermittent Fasting Improve High-Fat Diet-Induced Nonalcoholic Fatty Liver Disease in Obese Rats via the miR-122-5p/SREBP-1c/CPT1A Pathway
(Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy)
Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy - April 11, 2024 Category: Endocrinology Tags: Diabetes, Metabolic Syndrome and Obesity Source Type: research
Tailor-made molecular imprints for biological event intervention
Trends Biotechnol. 2024 Apr 10:S0167-7799(24)00063-5. doi: 10.1016/j.tibtech.2024.02.015. Online ahead of print.ABSTRACTMolecular imprints, which are crosslinked architectures containing specific molecular recognition cavities for targeting compounds, have recently transitioned from in vitro diagnosis to in vivo treatment. In current application scenarios, it has become an important topic to create new biomolecular recognition pathways through molecular imprinting, thereby inhibiting the pathogenesis and regulating the development of diseases. This review starts with a pathological analysis, mainly focusing on the correspo...
Source: Trends in Biotechnology - April 11, 2024 Category: Biotechnology Authors: Fan Ding Yue Ma Wensi Fan Jingjing Xu Guoqing Pan Source Type: research
Nascent shifts in renal cellular metabolism, structure, and function due to chronic empagliflozin in prediabetic mice
Am J Physiol Cell Physiol. 2024 Apr 1;326(4):C1272-C1290. doi: 10.1152/ajpcell.00446.2023. Epub 2024 Mar 4.ABSTRACTSodium-glucose cotransporter, type 2 inhibitors (SGLT2i) are emerging as the gold standard for treatment of type 2 diabetes (T2D) with renal protective benefits independent of glucose lowering. We took a high-level approach to evaluate the effects of the SGLT2i, empagliflozin (EMPA) on renal metabolism and function in a prediabetic model of metabolic syndrome. Male and female 12-wk-old TallyHo (TH) mice, and their closest genetic lean strain (Swiss-Webster, SW) were treated with a high-milk-fat diet (HMFD) plu...
Source: American Journal of Physiology. Cell Physiology - April 11, 2024 Category: Cytology Authors: Blythe D Shepard Jennifer Chau Ryan Kurtz Avi Z Rosenberg Pinaki Sarder Samuel P Border Brandon Ginley Olga Rodriguez Chris Albanese Grace Knoer Aarenee Greene Aline M A De Souza Suman Ranjit Moshe Levi Carolyn M Ecelbarger Source Type: research
Tailor-made molecular imprints for biological event intervention
Trends Biotechnol. 2024 Apr 10:S0167-7799(24)00063-5. doi: 10.1016/j.tibtech.2024.02.015. Online ahead of print.ABSTRACTMolecular imprints, which are crosslinked architectures containing specific molecular recognition cavities for targeting compounds, have recently transitioned from in vitro diagnosis to in vivo treatment. In current application scenarios, it has become an important topic to create new biomolecular recognition pathways through molecular imprinting, thereby inhibiting the pathogenesis and regulating the development of diseases. This review starts with a pathological analysis, mainly focusing on the correspo...
Source: Trends in Biotechnology - April 11, 2024 Category: Biotechnology Authors: Fan Ding Yue Ma Wensi Fan Jingjing Xu Guoqing Pan Source Type: research
Nascent shifts in renal cellular metabolism, structure, and function due to chronic empagliflozin in prediabetic mice
Am J Physiol Cell Physiol. 2024 Apr 1;326(4):C1272-C1290. doi: 10.1152/ajpcell.00446.2023. Epub 2024 Mar 4.ABSTRACTSodium-glucose cotransporter, type 2 inhibitors (SGLT2i) are emerging as the gold standard for treatment of type 2 diabetes (T2D) with renal protective benefits independent of glucose lowering. We took a high-level approach to evaluate the effects of the SGLT2i, empagliflozin (EMPA) on renal metabolism and function in a prediabetic model of metabolic syndrome. Male and female 12-wk-old TallyHo (TH) mice, and their closest genetic lean strain (Swiss-Webster, SW) were treated with a high-milk-fat diet (HMFD) plu...
Source: Am J Physiol Cell Ph... - April 11, 2024 Category: Cytology Authors: Blythe D Shepard Jennifer Chau Ryan Kurtz Avi Z Rosenberg Pinaki Sarder Samuel P Border Brandon Ginley Olga Rodriguez Chris Albanese Grace Knoer Aarenee Greene Aline M A De Souza Suman Ranjit Moshe Levi Carolyn M Ecelbarger Source Type: research
Nascent shifts in renal cellular metabolism, structure, and function due to chronic empagliflozin in prediabetic mice
Am J Physiol Cell Physiol. 2024 Apr 1;326(4):C1272-C1290. doi: 10.1152/ajpcell.00446.2023. Epub 2024 Mar 4.ABSTRACTSodium-glucose cotransporter, type 2 inhibitors (SGLT2i) are emerging as the gold standard for treatment of type 2 diabetes (T2D) with renal protective benefits independent of glucose lowering. We took a high-level approach to evaluate the effects of the SGLT2i, empagliflozin (EMPA) on renal metabolism and function in a prediabetic model of metabolic syndrome. Male and female 12-wk-old TallyHo (TH) mice, and their closest genetic lean strain (Swiss-Webster, SW) were treated with a high-milk-fat diet (HMFD) plu...
Source: American Journal of Physiology. Cell Physiology - April 11, 2024 Category: Cytology Authors: Blythe D Shepard Jennifer Chau Ryan Kurtz Avi Z Rosenberg Pinaki Sarder Samuel P Border Brandon Ginley Olga Rodriguez Chris Albanese Grace Knoer Aarenee Greene Aline M A De Souza Suman Ranjit Moshe Levi Carolyn M Ecelbarger Source Type: research
Nascent shifts in renal cellular metabolism, structure, and function due to chronic empagliflozin in prediabetic mice
Am J Physiol Cell Physiol. 2024 Apr 1;326(4):C1272-C1290. doi: 10.1152/ajpcell.00446.2023. Epub 2024 Mar 4.ABSTRACTSodium-glucose cotransporter, type 2 inhibitors (SGLT2i) are emerging as the gold standard for treatment of type 2 diabetes (T2D) with renal protective benefits independent of glucose lowering. We took a high-level approach to evaluate the effects of the SGLT2i, empagliflozin (EMPA) on renal metabolism and function in a prediabetic model of metabolic syndrome. Male and female 12-wk-old TallyHo (TH) mice, and their closest genetic lean strain (Swiss-Webster, SW) were treated with a high-milk-fat diet (HMFD) plu...
Source: Am J Physiol Cell Ph... - April 11, 2024 Category: Cytology Authors: Blythe D Shepard Jennifer Chau Ryan Kurtz Avi Z Rosenberg Pinaki Sarder Samuel P Border Brandon Ginley Olga Rodriguez Chris Albanese Grace Knoer Aarenee Greene Aline M A De Souza Suman Ranjit Moshe Levi Carolyn M Ecelbarger Source Type: research
Tailor-made molecular imprints for biological event intervention
Trends Biotechnol. 2024 Apr 10:S0167-7799(24)00063-5. doi: 10.1016/j.tibtech.2024.02.015. Online ahead of print.ABSTRACTMolecular imprints, which are crosslinked architectures containing specific molecular recognition cavities for targeting compounds, have recently transitioned from in vitro diagnosis to in vivo treatment. In current application scenarios, it has become an important topic to create new biomolecular recognition pathways through molecular imprinting, thereby inhibiting the pathogenesis and regulating the development of diseases. This review starts with a pathological analysis, mainly focusing on the correspo...
Source: Cancer Control - April 11, 2024 Category: Cancer & Oncology Authors: Fan Ding Yue Ma Wensi Fan Jingjing Xu Guoqing Pan Source Type: research
Nascent shifts in renal cellular metabolism, structure, and function due to chronic empagliflozin in prediabetic mice
Am J Physiol Cell Physiol. 2024 Apr 1;326(4):C1272-C1290. doi: 10.1152/ajpcell.00446.2023. Epub 2024 Mar 4.ABSTRACTSodium-glucose cotransporter, type 2 inhibitors (SGLT2i) are emerging as the gold standard for treatment of type 2 diabetes (T2D) with renal protective benefits independent of glucose lowering. We took a high-level approach to evaluate the effects of the SGLT2i, empagliflozin (EMPA) on renal metabolism and function in a prediabetic model of metabolic syndrome. Male and female 12-wk-old TallyHo (TH) mice, and their closest genetic lean strain (Swiss-Webster, SW) were treated with a high-milk-fat diet (HMFD) plu...
Source: American Journal of Physiology. Cell Physiology - April 11, 2024 Category: Cytology Authors: Blythe D Shepard Jennifer Chau Ryan Kurtz Avi Z Rosenberg Pinaki Sarder Samuel P Border Brandon Ginley Olga Rodriguez Chris Albanese Grace Knoer Aarenee Greene Aline M A De Souza Suman Ranjit Moshe Levi Carolyn M Ecelbarger Source Type: research
Nascent shifts in renal cellular metabolism, structure, and function due to chronic empagliflozin in prediabetic mice
Am J Physiol Cell Physiol. 2024 Apr 1;326(4):C1272-C1290. doi: 10.1152/ajpcell.00446.2023. Epub 2024 Mar 4.ABSTRACTSodium-glucose cotransporter, type 2 inhibitors (SGLT2i) are emerging as the gold standard for treatment of type 2 diabetes (T2D) with renal protective benefits independent of glucose lowering. We took a high-level approach to evaluate the effects of the SGLT2i, empagliflozin (EMPA) on renal metabolism and function in a prediabetic model of metabolic syndrome. Male and female 12-wk-old TallyHo (TH) mice, and their closest genetic lean strain (Swiss-Webster, SW) were treated with a high-milk-fat diet (HMFD) plu...
Source: Am J Physiol Cell Ph... - April 11, 2024 Category: Cytology Authors: Blythe D Shepard Jennifer Chau Ryan Kurtz Avi Z Rosenberg Pinaki Sarder Samuel P Border Brandon Ginley Olga Rodriguez Chris Albanese Grace Knoer Aarenee Greene Aline M A De Souza Suman Ranjit Moshe Levi Carolyn M Ecelbarger Source Type: research
Nascent shifts in renal cellular metabolism, structure, and function due to chronic empagliflozin in prediabetic mice
Am J Physiol Cell Physiol. 2024 Apr 1;326(4):C1272-C1290. doi: 10.1152/ajpcell.00446.2023. Epub 2024 Mar 4.ABSTRACTSodium-glucose cotransporter, type 2 inhibitors (SGLT2i) are emerging as the gold standard for treatment of type 2 diabetes (T2D) with renal protective benefits independent of glucose lowering. We took a high-level approach to evaluate the effects of the SGLT2i, empagliflozin (EMPA) on renal metabolism and function in a prediabetic model of metabolic syndrome. Male and female 12-wk-old TallyHo (TH) mice, and their closest genetic lean strain (Swiss-Webster, SW) were treated with a high-milk-fat diet (HMFD) plu...
Source: American Journal of Physiology. Cell Physiology - April 11, 2024 Category: Cytology Authors: Blythe D Shepard Jennifer Chau Ryan Kurtz Avi Z Rosenberg Pinaki Sarder Samuel P Border Brandon Ginley Olga Rodriguez Chris Albanese Grace Knoer Aarenee Greene Aline M A De Souza Suman Ranjit Moshe Levi Carolyn M Ecelbarger Source Type: research
Metabolic Obesity Phenotypes and Incident Cardiovascular Outcomes in Middle-Aged and Older Korean Adults: A Longitudinal 10-Year Analysis of the Korean Genome and Epidemiology Study
Metabolic Syndrome and Related Disorders,Volume 22, Issue 3, Page 232-239, April 2024. (Source: Metabolic Syndrome and Related Disorders)
Source: Metabolic Syndrome and Related Disorders - April 11, 2024 Category: Endocrinology Authors: Jae-Min Park Hye Sun Lee Juyeon Yang Dong-Hyuk Jung Ji-Won Lee Source Type: research
Insulin Resistance-Related Cardiometabolic Risk Among Nondiabetic Childbearing Age Females
Metabolic Syndrome and Related Disorders, Ahead of Print. (Source: Metabolic Syndrome and Related Disorders)
Source: Metabolic Syndrome and Related Disorders - April 11, 2024 Category: Endocrinology Authors: Nawoda Hewage Udaya Wijesekara Rasika Perera Source Type: research
Cystatin C is a predictor for long-term All-Cause and Cardiovascular Mortality in US Adults with Metabolic Syndrome
CONCLUSION: MetS patients with elevated CysC levels have a higher risk of all-cause, CVD, and cancer death. CysC may predict MetS all-cause and CVD mortality.PMID:38597157 | DOI:10.1210/clinem/dgae225 (Source: The Journal of Clinical Endocrinology and Metabolism)
Source: The Journal of Clinical Endocrinology and Metabolism - April 10, 2024 Category: Endocrinology Authors: Xiaoying Song Lijiao Xiong Tianting Guo Xue Chen Pinjun Zhang Xiaoan Zhang Zhen Liang Source Type: research
