Obsessive Compulsive Disorder
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Secondary Tics or Tourettism Associated With a Brain Tumor
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Tourette syndrome is generally considered to be a genetic disorder, but symptoms mimicking Tourette syndrome can be secondary to an underlying lesion disrupting the basal ganglia circuitry. Described here is a case of secondary tics, or tourettism, in a child with a large oligodendroglioma of the right temporal lobe extending to the basal ganglia. He presented with attention-deficit hyperactivity disorder, obsessive-compulsive disorder, and stimulant-induced tic disorder at the age of 11 years, and later also had also seizures. The family history was unremarkable. Cranial magnetic resonance imaging disclosed a right tempor...
Source: Pediatric Neurology - November 20, 2009 Category: Neurology Authors: Aimee F. Luat, Michael E. Behen, Csaba Juhász, Sandeep Sood, Harry T. Chugani Tags: Case Reports Source Type: journals
Long-Term, Post-Deep Brain Stimulation Management of a Series of 36 Patients Affected With Refractory Gilles de la Tourette Syndrome
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Conclusions. Gilles de la Tourette syndrome is a complex neuropsychiatric disorder with a significant prevalence in the general population. More than 50% of the patients with TS present a behavioral comorbidity, and anxiety and depression are, to various degrees, associated to this "waxing and waning" clinical picture. DBS in our experience proved to be a valid treatment modality for those patients who fail to respond to conservative treatment modalities. A multidisciplinary team is nevertheless necessary to properly handle this complex therapeutic option. (Source: Neuromodulation)
Source: Neuromodulation - November 20, 2009 Category: Neurology Authors: Domenico Servello, Marco Sassi, Arianna Brambilla, Stefano Defendi, Mauro Porta Source Type: journals
Ocpd
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Obsessive-compulsive personality disorder (OCPD) is a chronic, maladaptive pattern of dealing with other people and life challenges characterized by excessive rigidity and a need for control. Learn more about the definition of obsessive compulsive personality disorder. (Source: About.com Obsessive Compulsive Disorder)
Source: About.com Obsessive Compulsive Disorder - November 19, 2009 Category: Psychiatry Tags: health Source Type: consumer
OCD and Depression
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If you have OCD, you probably know that you are at a greater risk for developing other forms of mental illness. One of the most common mental illnesses to occur with OCD is major depressive disorder. Lets have a closer look at the relationship between OCD and depression and the impact of symptoms of depression on the treatment of OCD symptoms. (Source: About.com Obsessive Compulsive Disorder)
Source: About.com Obsessive Compulsive Disorder - November 19, 2009 Category: Psychiatry Tags: health Source Type: consumer
OCD and Personality
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It has long been thought that OCD and personality might be related. For example, Freud thought that personality characteristics such as indecisiveness and orderliness played a large role in the development of OCD. Although there does not appear to be a single OCD personality type that is vulnerable to developing OCD, recent research suggests a relationship between OCD and personality. (Source: About.com Obsessive Compulsive Disorder)
Source: About.com Obsessive Compulsive Disorder - November 18, 2009 Category: Psychiatry Tags: health Source Type: consumer
A randomised controlled trial of cognitive behavioural treatment for obsessive compulsive disorder in children and adolescents
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In this study, we
report on a randomised controlled trial of CBT for young people carried out in typical outpatient clinic conditions which
focused on cognitions. A randomised controlled trial compares 10 sessions of manualised cognitive behavioural treatment with
a 12-week waiting list for adolescents and children with OCD. Assessors were blind to treatment allocation. 21 consecutive
patients with OCD aged between 9 and 18 years were recruited. The group who received treatment improved more than a comparison
group who waited for 3 months. The second group was treated subsequently using the same protocol and...
Source: European Child & Adolescent Psychiatry - November 17, 2009 Category: Psychiatry Tags: European Child & Adolescent Psychiatry Source Type: journals
The PANDAS subgroup of tic disorders and childhood-onset obsessive–compulsive disorder
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Abstract: Diagnosis and treatment of the PANDAS (pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections) variant of Gilles de la Tourette syndrome (GTS) and childhood-onset obsessive–compulsive disorder (OCD) are still controversial issues. Most cross-sectional studies confirm a significant association between GTS and the development of an immune response against group A β-hemolytic streptococcus (GABHS). Moreover, longitudinal retrospective studies suggest that a recent exposure to GABHS might be a risk factor for the onset of tics and obsessive–compulsive symptoms. However, further ...
Source: Journal of Psychosomatic Research - November 16, 2009 Category: Psychiatry & Psychology Authors: Davide Martino, Giovanni Defazio, Gavin Giovannoni Tags: Original Articles Source Type: journals
Clinical phenomenology and phenotype variability in Tourette syndrome
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Abstract: Tourette syndrome (TS) is a neurodevelopmental disorder with a rich phenomenology that includes simple and complex motor and vocal tics as well as multiple comorbidities. From a nosological perspective, it is evident that a continuum of tic severity exists, of which TS is the most severe and rare form, while transient tics and chronic tics represent milder forms. From a psychopathology perspective, TS is often concurrent with obsessive–compulsive disorder (OCD) and attention deficit hyperactivity disorder (ADHD); these disorders appear to define TS “types” TS only, TS+OCD, and TS+OCD+ADHD. Additional clinic...
Source: Journal of Psychosomatic Research - November 16, 2009 Category: Psychiatry & Psychology Authors: Marco A. Grados, Carol A. Mathews Tags: Original Articles Source Type: journals
Clinical course of Tourette syndrome
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Conclusion: Although tics are the sine qua non of TS, they are often not the most enduring or impairing symptoms in children with TS. Measures used to enhance self-esteem, such as encouraging strong friendships and the exploration of interests, are crucial to ensuring positive adulthood outcome in TS. (Source: Journal of Psychosomatic Research)
Source: Journal of Psychosomatic Research - November 16, 2009 Category: Psychiatry & Psychology Authors: Michael H. Bloch, James F. Leckman Tags: Original Articles Source Type: journals
Libel in Fact: Aspiring to Rational Judgments Using DSM-I
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A 1964 poll Fact magazine invited members of the American Psychiatric Association to comment on then-Senator Barry Goldwater's personality. Last week, I continued my examination of the results of the poll, particularly focusing on the difference between, intuitive, automatic-seeming perceptions of personality versus logical, analytical reactions (see here).An example of a likely intuitive reaction was a respondent's comment regarding the Senator: "He frightens the hell out of me."In contrast to such intuitive reactions, diagnostic evaluations of Senator Goldwater ought to be more logical and analytical. Psychiatrists are t...
Source: Psychology Today Personality Center - November 15, 2009 Category: Psychiatry & Psychology Authors: John D. Mayer, Ph.D. Tags: Personality American Psychiatric Association checklists delusions hallucinations diagnostic and statistical manual diagnostic evaluations disorganized speech dsm iii dsm iv tr fact magazine impressions manifestations mental disorde Source Type: consumer
Parent-Child Agreement in the Assessment of Obsessive-Compulsive Disorder
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(Source: Journal of Clinical Child & Adolescent Psychology)
Source: Journal of Clinical Child & Adolescent Psychology - November 13, 2009 Category: Psychiatry & Psychology Authors: Canavera, Kristin E.Wilkins, Kendall C.Pincus, Donna B.Ehrenreich-May, Jill T. Source Type: journals
Can mindaltering drugs have mental health benefits?
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Hallucinogenic drugs such as LSD are making their way back into mainstream psychotherapy. (Source: Telegraph Health)
Source: Telegraph Health - November 13, 2009 Category: Consumer Health News Tags: lsd mdma ecstacy psychotherapy psychedelic drugs OCD post traumatic stress Source Type: news
Hypomania with hypersexuality following bilateral anterior limb stimulation in obsessive-compulsive disorder.
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This 28-year-old Chinese man was referred for deep brain stimulation (DBS) evaluation for an 8-year history of refractory obsessive-compulsive disorder. After the patient had signed an informed consent, the authors implanted DBS leads. Hypomania with hypersexuality was noted on stimulation at Contact 2 and became aggravated with a higher voltage (>/=3 V) during chronic bilateral DBS. After the voltage was decreased to 1 V, the patient's hypomanic symptoms subsided and his libido returned to baseline.
PMID: 19911886 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - November 13, 2009 Category: Neurosurgery Authors: Chang CH, Chen SY, Hsiao YL, Tsai ST, Tsai HC Tags: J Neurosurg Source Type: journals
Rotigotine/selegiline: Impulse control and obsessive compulsive disorders: 3 case reports
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(Source: Reactions)
Source: Reactions - November 11, 2009 Category: Drugs & Pharmacology Tags: Short communication Source Type: journals
Disorganization of anatomical connectivity in Obsessive Compulsive Disorder: a multi-parameter Diffusion Tensor Imaging study in a subpopulation of patients.
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Obsessive-compulsive disorder (OCD) is thought to involve large scale brain systems but the anatomical connectivity via association fibers has not been specifically investigated yet. We evaluated organization and directionality of the major fiber bundles in a subpopulation of OCD, including washers and checkers who presented decision making deficits, by measuring MRI parameters related to water self-diffusion (Fractional Anisotropy - FA) and fiber directionality (Principal Diffusion Direction - PDD) in 15 OCD and 16 control subjects. OCD patients showed significantly lower FA and altered PDD along the corpus callosum, ...
Source: Neurobiology of Disease - November 11, 2009 Category: Neurology Authors: Garibotto V, Scifo P, Gorini A, Clarke RA, Brambati S, Bellodi L, Perani D Tags: Neurobiol Dis Source Type: journals
The Obsessive Compulsive Drinking Scale: Translation into Dutch and Possible Modifications
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Eur Addict Res 1997;3:116-122 (DOI:10.1159/000259164) (Source: European Addiction Research : Last 20 articles)
Source: European Addiction Research : Last 20 articles - November 10, 2009 Category: Addiction Source Type: journals
Jeremy Piven = Soy or Sushi - NOT
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Jeremy Piven seems to have a serious case of food OCD. The Entourage actor finds a food he likes and just goes for it - all or nothing. Recently, the 43-year-old actor claimed he developed Mercury poisoning from sushi and was forced to leave a Broadway play he was starring in. Before you swear off sushi, relax, Piven wasn’t just eating the occasional sushi dinner; he was eating A LOT of sushi sometimes twice a day, everyday, for the past 20 years. After giving up sushi he moved on to his latest food obsession - soy milk. And, since we know he isn’t into moderation he found himself drinking up to 12 cups or about 3/4 of...
Source: Health WorldNet - November 10, 2009 Category: Consumer Health News Source Type: news
What are Your Symptoms?
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There are at least 5 different types of OCD symptoms such as hoarding, obsessive thoughts with no compulsions and symmetry obsessions. What are you symptoms and how do you deal with them? Share Your ExperienceWhat are Your Symptoms? originally appeared on About.com Obsessive-Compulsive Disorder on Saturday, November 14th, 2009 at 08:25:47.Permalink | Comment | Email this (Source: About.com Obsessive Compulsive Disorder)
Source: About.com Obsessive Compulsive Disorder - November 9, 2009 Category: Psychiatry Source Type: consumer
Carbamazepine for serotonin reuptake inhibitor nonresponder case of obsessive compulsive disorder
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Aggarwal Ashish, Jain Manish, Garg Amit, Jiloha R CIndian Journal of Medical Sciences 2009 63(10):468-469 (Source: Indian Journal of Medical Sciences)
Source: Indian Journal of Medical Sciences - November 7, 2009 Category: Journals (General) Authors: Aggarwal Ashish, Jain Manish, Garg Amit, Jiloha R C Source Type: journals
Clinical Trial
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Clinical trials are experiments that test a large number of people under controlled conditions to evaluate the effectiveness of new treatments. Although clinical trials are often used to evaluate new drugs, they can also be used to test different forms of psychotherapy. (Source: About.com Obsessive Compulsive Disorder)
Source: About.com Obsessive Compulsive Disorder - November 6, 2009 Category: Psychiatry Tags: health Source Type: consumer
Ortho Clinical Diagnostics Launches First-of-its-kind Remote Monitoring Center(Nov 4, 2009)
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Paris, France (November 4th, 2009) Ortho Clinical Diagnostics (OCD) today announced the launch of a first-of-its-kind 24-7 central command center in Strasbourg, France, that continuously tracks the condition of clinical laboratory instrument performance. The Remote Monitoring Center in Strasbourg provides unique predictive monitoring services to laboratories throughout Europe and the Asia-Pacific region by continuously detecting and tracking potential instrument problems up to 30 days in advance, before they interrupt the ability of the lab to deliver quality test results..... (Source: Johnson and Johnson)
Source: Johnson and Johnson - November 4, 2009 Category: Pharmaceuticals Source Type: organizations
Video guide to cognitive behavioural therapy
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Authoritative information from the British Medical Journal on CBT, a psychotherapy used to treat depression, anxiety, panic attacks and obsessive-compulsive disorder (Source: Guardian Unlimited Science)
Source: Guardian Unlimited Science - November 4, 2009 Category: Science Tags: BMJ Group news Depression in adults Anxiety Panic attacks Obsessive-compulsive disorder Health & wellbeing Life and style Mental health Society Psychology Science guardian.co.uk Editorial Source Type: news
ORIGINAL ARTICLE: Altered Corticostriatal Functional Connectivity in Obsessive-compulsive Disorder
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Conclusions This study directly supports the hypothesis that OCD is associated with functional alterations of brain corticostriatal networks. Specifically, our findings emphasize abnormal and heightened functional connectivity of ventrolimbic corticostriatal regions in patients with OCD. (Source: Archives of General Psychiatry)
Source: Archives of General Psychiatry - November 2, 2009 Category: Psychiatry Authors: Harrison, B. J., Soriano-Mas, C., Pujol, J., Ortiz, H., Lopez-Sola, M., Hernandez-Ribas, R., Deus, J., Alonso, P., Yucel, M., Pantelis, C., Menchon, J. M., Cardoner, N. Tags: Neurology, Functional Imaging, Psychiatry, Obsessive-Compulsive Disorder, Radiologic Imaging, Magnetic Resonance Imaging Original Article Source Type: journals
ORIGINAL ARTICLE: Association of the Glutamate Transporter Gene SLC1A1 With Atypical Antipsychotics-Induced Obsessive-compulsive Symptoms
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Conclusions These results suggest that sequence variations in SLC1A1 are associated with susceptibility to AAP-induced OC symptoms. This is the first published pharmacogenetic study on this phenomenon and provides preliminary evidence of the involvement of glutamatergic neurotransmission in the pathogenesis of AAP-induced OC symptoms. (Source: Archives of General Psychiatry)
Source: Archives of General Psychiatry - November 2, 2009 Category: Psychiatry Authors: Kwon, J. S., Joo, Y. H., Nam, H. J., Lim, M., Cho, E.-Y., Jung, M. H., Choi, J.-S., Kim, B., Kang, D.-H., Oh, S., Park, T., Hong, K. S. Tags: Psychiatry, Obsessive-Compulsive Disorder, Psychopharmacology, Schizophrenia, Drug Therapy, Adverse Effects, Drug Therapy, Other, Genetics, Genetic Disorders Original Article Source Type: journals
Altered Corticostriatal Functional Connectivity in Obsessive-compulsive Disorder [Original Article]
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Conclusions This study directly supports the hypothesis that OCD is associated with functional alterations of brain corticostriatal networks. Specifically, our findings emphasize abnormal and heightened functional connectivity of ventrolimbic corticostriatal regions in patients with OCD. (Source: Archives of General Psychiatry)
Source: Archives of General Psychiatry - November 2, 2009 Category: Psychiatry Authors: Harrison, B. J., Soriano-Mas, C., Pujol, J., Ortiz, H., Lopez-Sola, M., Hernandez-Ribas, R., Deus, J., Alonso, P., Yucel, M., Pantelis, C., Menchon, J. M., Cardoner, N. Tags: Neurology, Functional Imaging, Psychiatry, Obsessive-Compulsive Disorder, Radiologic Imaging, Magnetic Resonance Imaging Original Article Source Type: journals
Association of the Glutamate Transporter Gene SLC1A1 With Atypical Antipsychotics-Induced Obsessive-compulsive Symptoms [Original Article]
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Conclusions These results suggest that sequence variations in SLC1A1 are associated with susceptibility to AAP-induced OC symptoms. This is the first published pharmacogenetic study on this phenomenon and provides preliminary evidence of the involvement of glutamatergic neurotransmission in the pathogenesis of AAP-induced OC symptoms. (Source: Archives of General Psychiatry)
Source: Archives of General Psychiatry - November 2, 2009 Category: Psychiatry Authors: Kwon, J. S., Joo, Y. H., Nam, H. J., Lim, M., Cho, E.-Y., Jung, M. H., Choi, J.-S., Kim, B., Kang, D.-H., Oh, S., Park, T., Hong, K. S. Tags: Psychiatry, Obsessive-Compulsive Disorder, Psychopharmacology, Schizophrenia, Drug Therapy, Adverse Effects, Drug Therapy, Other, Genetics, Genetic Disorders Original Article Source Type: journals
Arrhythmias and increased neuro-endocrine stress response during physicians' night shifts: a randomized cross-over trial
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Conclusion
Our results highlight the association of OCD with an increased risk profile for cardiovascular disease. In addition to the acute effects observed, frequent night-calls over a longer period possibly elicit sustained alterations in cardiovascular homeostasis. (Source: European Heart Journal)
Source: European Heart Journal - November 1, 2009 Category: Cardiology Authors: Rauchenzauner, M., Ernst, F., Hintringer, F., Ulmer, H., Ebenbichler, C. F., Kasseroler, M.-T., Joannidis, M. Tags: Arrhythmia/electrophysiology Source Type: journals
Voxel-wise meta-analysis of grey matter changes in obsessive-compulsive disorder [REVIEW ARTICLES]
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Conclusions
The results support a dorsal prefrontal–striatal model of the
disorder and raise the question of whether functional alterations in other
brain regions commonly associated with OCD, such as the orbitofrontal cortex,
may reflect secondary compensatory strategies. Whether the reported
differences between participants with OCD and controls precede the onset of
the symptoms and whether they are specific to OCD remains to be
established. (Source: The British Journal of Psychiatry)
Source: The British Journal of Psychiatry - November 1, 2009 Category: Psychiatry Authors: Radua, J., Mataix-Cols, D. Tags: REVIEW ARTICLES Source Type: journals
Clozapine: Obsessive-compulsive disorders: 7 case reports
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(Source: Reactions)
Source: Reactions - October 31, 2009 Category: Drugs & Pharmacology Tags: Short communication Source Type: journals
How to get your doctor to sing Happy Birthday while he washes his hands (satire)
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(NaturalNews) I recently saw a poster in a medical building that stopped me cold. It was about influenza, and it said the following: To avoid spreading germs, wash your hands for as long as it takes to sing Happy Birthday to yourself.I did a double take. Really? Wash your hands while you sing Happy Birthday as a timing mechanism?Apparently, this is an important bit of advice for teaching the masses how to successfully wash their own hands. I guess they couldn't use Row, Row, Row Your Boat because that song just goes on forever, and people would be stuck at the sink washing their hands like disturbed obsessive-compulsive ha...
Source: NaturalNews.com - October 31, 2009 Category: Consumer Health Advice Source Type: news
Psychotherapy for OCD
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Psychological therapies are effective treatments for reducing the frequency and intensity of symptoms of OCD. Effective psychological treatments for OCD emphasize changes in behavior and/or thoughts. When appropriate, psychotherapy can be done alone or combined with medication. The two main types of psychological therapies for OCD are cognitive-behavior therapy (CBT) and exposure and response prevention (ERP) therapy. (Source: About.com Obsessive Compulsive Disorder)
Source: About.com Obsessive Compulsive Disorder - October 31, 2009 Category: Psychiatry Tags: health Source Type: consumer
Executive Function Deficits, Attention-Deficit/Hyperactivity Disorder, Tics, and Obsessive-Compulsive Disorder in an Adolescent
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Journal of Child and Adolescent Psychopharmacology Oct 2009, Vol. 19, No. 5: 585-588. (Source: Journal of Child and Adolescent Psychopharmacology)
Source: Journal of Child and Adolescent Psychopharmacology - October 30, 2009 Category: Pediatrics Tags: article Source Type: journals
The Uncertainty Paradox
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I know a secret--a deeply profound, life-changing secret--one learned through the school of hard knocks in one of its most grueling courses. It is nothing short of the very key to living with uncertainty, this secret; and because you, dear bloggie (is that what one calls a reader of a blog?), have been so supportive of this outreach project, I will share it with you, free of charge and with no obligation. (You are very welcome.) To prepare yourself for the sage, paradoxical wisdom I am about to impart, I suggest you close your eyes and imagine a dramatic drum roll. Picture, if it helps, the clouds in the sky parting above ...
Source: Psychology Today Anxiety Center - October 30, 2009 Category: Psychiatry & Psychology Authors: Jeff Bell Tags: Anxiety best efforts blog chipmunks clouds in the sky compulsion contrary counterintuitive crickets deep breath doubt drum roll efficacy extremes footnotes living with uncertainty obligation obsession OCD outreach pro Source Type: consumer
Coping With Stigma
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If you have OCD, you know that the stigma attached to mental illness can make it difficult to cope. Even though it is clear that OCD has biological roots, there are people who continue to believe that people challenged with mental illness should be able to "snap out of it." Have you ever been discriminated against or stigmatized because of your OCD? What happened and how did you cope with it? Share your experience.Coping With Stigma originally appeared on About.com Obsessive-Compulsive Disorder on Monday, November 9th, 2009 at 09:18:50.Permalink | Comment | Email this (Source: About.com Obsessive Compulsive Disorder)
Source: About.com Obsessive Compulsive Disorder - October 30, 2009 Category: Psychiatry Source Type: consumer
Psychiatric and Psychotherapeutic Literacy: Attitudes To, and Knowledge of, Psychotherapy
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Conclusion: Lay people show a curious pattern on insight, ignorance and naivety with regard to the cause and cure of mental disorders. They appear to have a modestly realistic but somewhat naive view of the process and efficacy of psychotherapy. This may influence how they react to their own and others’ mental illness. It has clear implications for education in psychiatric literacy. (Source: International Journal of Social Psychiatry)
Source: International Journal of Social Psychiatry - October 27, 2009 Category: Psychiatry Authors: Furnham, A. Tags: Articles Source Type: journals
Arthroscopic technique for fragment fixation using absorbable pins for osteochondritis dissecans of the humeral capitellum: a report of 4 cases
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Abstract This is the first report to describe a method of arthroscopic osteochondral fixation using absorbable pins to treat osteochondritis
dissecans (OCD) of the capitellum. Four adolescent baseball players with OCD of the capitellum were treated, and good short-term
results were obtained. During this arthroscopic procedure, the elbow was maintained in the maximum flexed position, and posterolateral
portals were used to visualize the lesion, perform drilling, and insert the pins. This procedure is less invasive and easier
to perform than other fixation procedures that require harvesting or production of au...
Source: Knee Surgery, Sports Traumatology, Arthroscopy - October 27, 2009 Category: Orthopaedics Tags: Knee Surgery, Sports Traumatology, Arthroscopy Source Type: journals
Treatment of osteochondral lesions of the talus: a systematic review
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Abstract The aim of this study was to summarize all eligible studies to compare the effectiveness of treatment strategies for osteochondral
defects (OCD) of the talus. Electronic databases from January 1966 to December 2006 were systematically screened. The proportion
of the patient population treated successfully was noted, and percentages were calculated. For each treatment strategy, study
size weighted success rates were calculated. Fifty-two studies described the results of 65 treatment groups of treatment strategies
for OCD of the talus. One randomized clinical trial was identified. Seven studies descri...
Source: Knee Surgery, Sports Traumatology, Arthroscopy - October 27, 2009 Category: Orthopaedics Tags: Knee Surgery, Sports Traumatology, Arthroscopy Source Type: journals
Treatment-resistant Obsessive-compulsive Disorder in Young People: Assessment and Treatment Strategies
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This article outlines potential barriers in treatment and highlights strategies for optimising outcome, with particular focus on cognitive behavioural techniques. (Source: Child and Adolescent Mental Health)
Source: Child and Adolescent Mental Health - October 27, 2009 Category: Psychiatry Authors: Georgina Krebs, Isobel Heyman Source Type: journals
Thalamic deep brain stimulation for treatment-refractory Tourette syndrome: Two-year outcome
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Conclusions: At 24-month follow-up, tic severity was improved in patients with intractable Tourette syndrome (TS) who underwent bilateral thalamic deep brain stimulation. Available data from 15 of 18 patients also showed that neuropsychiatric symptoms were improved and cognitive performances were not disadvantaged. Controlled studies on larger cohorts with blinded protocols are needed to verify that this procedure is effective and safe for selected patients with TS.
Level of evidence: This study provides class IV evidence that bilateral thalamic deep brain stimulation reduces global tic severity measured 24 months after im...
Source: Neurology - October 26, 2009 Category: Neurology Authors: Porta, M., Brambilla, A., Cavanna, A. E., Servello, D., Sassi, M., Rickards, H., Robertson, M. M. Tags: Tourette syndrome, Tics, Neuropsychological assessment, All Psychiatric disorders, Class IV ARTICLES Source Type: journals
Antipsychotics: Metabolic disorders, tardive dyskinesia and obsessive-compulsive symptoms (first report with ziprasidone): case report
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(Source: Reactions)
Source: Reactions - October 26, 2009 Category: Drugs & Pharmacology Tags: Short communication Source Type: journals
[Tics and Tourette's syndrome throughout the life span.]
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Chronic motor and vocal tics lasting longer than a year are classified as Tourette's syndrome (TS). Tics mostly manifest before the age of 11 years. Boys are affected at a threefold higher rate than girls. Tics are often worst at the age of 14; in 50% of the cases the tic symptoms will remit nearly completely. Severely affected patients often suffer from comorbidities. In childhood and adolescence the most common comorbid condition is attention deficit hyperactivity disorder (ADHD). Obsessive-compulsive behaviour, anxiety and affective disorder might occur in the course of TS. A dysregulation in the dopaminergic neurot...
Source: Der Nervenarzt - October 25, 2009 Category: Neurology Authors: Neuner I, Ludolph A Tags: Nervenarzt Source Type: journals
MRI study of the cavum septum pellucidum in obsessive–compulsive disorder
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Abstract The cavum septum pellucidum (CSP), a putative marker of neurodevelopmental anomaly, has been associated with an increased
risk of several psychiatric disorders. The purpose of this study was to evaluate the CSP in patients with obsessive–compulsive
disorder (OCD) compared with healthy control subjects. Seventy-one patients with OCD and 71 healthy volunteers matched for
age and sex were evaluated with magnetic resonance imaging. We evaluated the CSP using criteria employed in previous studies:
presence of the CSP, length of the CSP, and overall size of the CSP, measured in five grades, ranging from...
Source: European Archives of Psychiatry and Clinical Neuroscience - October 24, 2009 Category: Neuroscience Tags: European Archives of Psychiatry and Clinical Neuroscience Source Type: journals
"I can't let anything go:" A case study with psychological testing of a patient with pathologic hoarding.
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This report describes a particular individual with characteristic features of hoarding, which is explored through formal psychological testing.
PMID: 19845090 [PubMed - in process] (Source: American Journal of Psychotherapy)
Source: American Journal of Psychotherapy - October 24, 2009 Category: Psychiatry & Psychology Authors: Koretz J, Gutheil TG Tags: Am J Psychother Source Type: journals
Is a psychodynamic perspective relevant to the clinical management of obsessive-compulsive disorder?
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Obsessive-compulsive disorder (OCD) can be a severe and disabling condition with considerable variability in clinical presentation, course, and treatment response. Based upon demonstrated efficacy in clinical trials, selective serotonin reuptake inhibitors (SSRIs) and cognitive behavioral therapy (CBT) have become the treatments of choice for patients with OCD. By contrast, psychodynamic formulations and treatments are often considered irrelevant or contraindicated. In the present paper, the authors present five clinical cases of OCD where psychodynamic understanding and/or treatment was essential for optimizing outcom...
Source: American Journal of Psychotherapy - October 24, 2009 Category: Psychiatry & Psychology Authors: Chlebowski S, Gregory RJ Tags: Am J Psychother Source Type: journals
Obsessive-compulsive behavior spectrum: Refining the research agenda for DSM-V
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Abstract: The American Psychiatric Association, in collaboration with the World Health Organization and the National Institutes of Health, has undertaken a 5-year international research planning effort in preparation for the formal revision of the Diagnostic and Statistical Manual of Mental Disorders. One element of the project was a conference titled “Obsessive-Compulsive Behavior Spectrum,” in which participants reviewed an array of disorders that cross current diagnostic categories. Questions raised challenge those responsible for the DSM-V revision to assess the pros and cons of changing definitions, boundaries, or...
Source: Psychiatry Research - October 23, 2009 Category: Psychiatry Authors: Darrel A. Regier Tags: Special Section: Obsessive-Compulsive Behavior Spectrum Source Type: journals
Cross-cutting issues and future directions for the OCD spectrum
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Abstract: The research planning agenda for DSM-V examined possible similarities in phenomenology, comorbidity, familial and genetic features, brain circuitry, and treatment response between obsessive-compulsive disorder (OCD) and several related disorders that are characterized by repetitive thoughts or behaviors. Such data support a re-examination of the DSM-IV-TR classification of OCD and the anxiety disorders, with possible inclusion of a group of obsessive-compulsive spectrum disorders (OCSDs) in DSM-V. Various disorders were systematically examined for inclusion in such a grouping, and later a smaller number were dete...
Source: Psychiatry Research - October 23, 2009 Category: Psychiatry Authors: Eric Hollander, Suah Kim, Ashley Braun, Daphne Simeon, Joseph Zohar Tags: Special Section: Obsessive-Compulsive Behavior Spectrum Source Type: journals
Overview of genetics and obsessive–compulsive disorder
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Abstract: This paper reviews the current state of research into the genetics of obsessive–compulsive disorder (OCD). Heredity has a major role in OCD etiology. This evidence comes from several methodological approaches such as family, twin, and segregation analysis studies. A major single gene effect as well as a polygenic hypothesis has been suggested based on segregation studies. In addition, candidate gene association and linkage analyses have shown not only one gene, but a few interesting genes and areas of the genome that may be relevant in OCD. In this search for genes, new definitions of the OCD phenotype have eme...
Source: Psychiatry Research - October 23, 2009 Category: Psychiatry Authors: Humberto Nicolini, Paul Arnold, Gerald Nestadt, Nuria Lanzagorta, James L. Kennedy Tags: Special Section: Obsessive-Compulsive Behavior Spectrum Source Type: journals
Cross-species models of OCD spectrum disorders
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Abstract: Several axis-I neuropsychiatric disorders are characterised by repetitive motor habits suggestive of underlying inhibitory dyscontrol, and may constitute members of a putative obsessive–compulsive (OC) spectrum. Notable examples include obsessive–compulsive disorder (OCD) and trichotillomania (repetitive hair-pulling). Multiple tiers of evidence link these conditions with underlying dysregulation of fronto-striatal circuitry and monoamine systems. These abnormalities represent key targets for existing and novel treatment interventions. Nonetheless, the brain bases of these conditions, and treatment mechanisms...
Source: Psychiatry Research - October 23, 2009 Category: Psychiatry Authors: Vasileios Boulougouris, Samuel R. Chamberlain, Trevor W. Robbins Tags: Special Section: Obsessive-Compulsive Behavior Spectrum Source Type: journals
The relationship between impulse-control disorders and obsessive–compulsive disorder: A current understanding and future research directions
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Abstract: Impulse-control disorders (ICDs) constitute a heterogeneous group of conditions linked diagnostically by difficulties in resisting “the impulse, drive, or temptation to perform an act that is harmful to the person or to others.” Specific ICDs share clinical, phenomenological and biological features with obsessive–compulsive disorder (OCD) that have suggested that these disorders might be categorized together. However, other data suggest significant differences between OCD and ICDs. In this article, clinical, phenomenological and biological features of the formal ICDs are reviewed and compared and contrasted...
Source: Psychiatry Research - October 23, 2009 Category: Psychiatry Authors: Marc Nicholas Potenza, Lorrin Michael Koran, Stefano Pallanti Tags: Special Section: Obsessive-Compulsive Behavior Spectrum Source Type: journals
Tourette's syndrome, trichotillomania, and obsessive–compulsive disorder: How closely are they related?
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Abstract: The question of whether Tourette's syndrome (TS) and trichotillomania (TTM) are best conceptualized as obsessive–compulsive spectrum disorders was raised by family studies demonstrating a close relationship between TS and obsessive–compulsive disorder (OCD), and by psychopharmacological research indicating that both TTM and OCD respond more robustly to clomipramine than to desipramine. A range of studies have subsequently allowed comparison of the phenomenology, psychobiology, and management of TS and TTM, with that of OCD. Here we briefly review this literature. The data indicate that there is significant ps...
Source: Psychiatry Research - October 23, 2009 Category: Psychiatry Authors: Ygor Arzeno Ferrão, Euripedes Miguel, Dan Joseph Stein Tags: Special Section: Obsessive-Compulsive Behavior Spectrum Source Type: journals
