Proton Therapy
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Dose-Rate Effects When Estimating Risks for Second Malignancies: In Regard to Fontenot et al (Int J Radiat Oncol Biol Phys 2009;74:616–622)
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To the Editor: In the work by Fontenot et al. , the risk for developing a second malignancy after prostate radiation therapy was estimated for proton therapy and intensity-modulated X-ray therapy (IMRT). The authors conclude that proton therapy can reduce the risk for a second cancer when compared with IMRT. (Source: International Journal of Radiation Oncology * Biology * Physics)
Source: International Journal of Radiation Oncology * Biology * Physics - November 19, 2009 Category: Radiology Authors: Harald Paganetti, Basit S. Athar, Bryan Bednarz Tags: Letters to the Editor Source Type: journals
A systematic review of proton therapy in the treatment of chondrosarcoma of the skull base
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Abstract Chondrosarcoma (CSA) of the skull base (SB) is an uncommon, slowly growing, neoplasm comprising approximately 0.1% of all
intracranial tumors and 6% of SB lesions. Even though its growth is slow, CSA is a potentially lethal tumor. The therapeutic
approach to CSA of the SB is still controversial and clinical experience is limited because of the relative rarity of this
tumor. The use of proton therapy (PT) after maximal surgery is widely accepted, but there are no controlled studies demonstrating
the need of PT and its superiority in comparison to radiotherapy with photons. We conducted a systematic r...
Source: Urosurgical Review - November 17, 2009 Category: Urology & Nephrology Tags: Neurosurgical Review Source Type: journals
Radiation protection constraints for use of proton and ion accelerators in medicine
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This paper gives some guidelines for radiation protection at proton therapy facilities. The energy and angular distribution of secondary radiation from thick iron and tissue targets bombarded by 250-MeV protons were calculated with Monte Carlo simulations in order to emphasise the influence of the various components of the radiation field on the shielding design. The main constraints for radiation protection (e.g. workload, use and occupancy factors, etc.), shielding design (including access mazes) and the estimate of material activation are also discussed with some practical examples. (Source: Radiation Protection Dosimetry)
Source: Radiation Protection Dosimetry - November 16, 2009 Category: Radiology Authors: Agosteo, S. Tags: Articles Source Type: journals
First Patients Complete Treatment at ProCure Proton Therapy Center in Oklahoma City
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OKLAHOMA CITY--(HSMN NewsFeed)--The first group of patients have completed treatment at the ProCure Proton Therapy Center in Oklahoma City, the sixth center in the country to provide proton therapy, an alternative to X-ray radiation that spares healthy tis... Devices, OncologyProCure Treatment Centers, Proton Therapy, proton beam, radiotherapy (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - November 12, 2009 Category: Pharmaceuticals Source Type: news
St. Jude And UF Proton Therapy Institute To Begin Proton Therapy Clinical Trial
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St. Jude Children's Research Hospital and the University of Florida Proton Therapy Institute have formed a collaboration to provide proton therapy for St. Jude patients. The announcement follows the approval of the first clinical study to evaluate the use of proton therapy for rare brain cancers in children younger than 3 years old. Under the clinical protocol, St. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 11, 2009 Category: Consumer Health News Tags: Cancer / Oncology Source Type: news
St. Jude And UF Proton Therapy Institute To Begin Proton Therapy Clinical Trial
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St. Jude Children's Research Hospital and the University of Florida Proton Therapy Institute have formed a collaboration to provide proton therapy for St. Jude patients. The announcement follows the approval of the first clinical study to evaluate the use of proton therapy for rare brain cancers in children younger than 3 years old. Under the clinical protocol, St. Jude will refer patients to receive proton therapy at the UF Proton Therapy Institute in Jacksonville, Fla. (Source: Cancer / Oncology News From Medical News Today)
Source: Cancer / Oncology News From Medical News Today - November 11, 2009 Category: Cancer & Oncology Tags: Cancer / Oncology Source Type: news
Proton Therapy Boost Reduces Prostate Cancer Recurrence
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A boost of proton therapy led to less biochemical recurrence of prostate cancer in a new study, although it was not a head-to-head comparison of proton therapy and conventional radiation technology. Medscape Medical News (Source: Medscape Radiology Headlines)
Source: Medscape Radiology Headlines - November 10, 2009 Category: Radiology Tags: Hematology-Oncology Source Type: info
St. Jude Children's Research Hospital And UF Proton Therapy Institute To Begin Proton Therapy Clinical Trial
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St. Jude Children's Research Hospital and the University of Florida Proton Therapy Institute have formed a collaboration to provide proton therapy for St. Jude patients. The announcement follows the approval of the first clinical study to evaluate the use of proton therapy for rare brain cancers in children younger than 3 years old. Under the clinical protocol, St. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 10, 2009 Category: Consumer Health News Tags: Cancer / Oncology Source Type: news
St. Jude Children's Research Hospital And UF Proton Therapy Institute To Begin Proton Therapy Clinical Trial
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St. Jude Children's Research Hospital and the University of Florida Proton Therapy Institute have formed a collaboration to provide proton therapy for St. Jude patients. The announcement follows the approval of the first clinical study to evaluate the use of proton therapy for rare brain cancers in children younger than 3 years old. Under the clinical protocol, St. Jude will refer patients to receive proton therapy at the UF Proton Therapy Institute in Jacksonville, Fla. (Source: Cancer / Oncology News From Medical News Today)
Source: Cancer / Oncology News From Medical News Today - November 10, 2009 Category: Cancer & Oncology Tags: Cancer / Oncology Source Type: news
Proton Therapy Is Promising, But Pricey; Some Are Concerned Patients Will Be Steered To Expensive Treatment That May Not Be More Effective
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As he fought the brain cancer that killed him Aug. 25, Sen. Edward Kennedy received proton radiation treatment at Massachusetts General Hospital. People asked me when Sen. Kennedy died, 'What did it (proton therapy) buy him? said Leonard Arzt, executive director of the National Association for Proton Therapy in Washington, D.C. (Source: Cancercompass News: Other Cancer)
Source: Cancercompass News: Other Cancer - November 10, 2009 Category: Cancer & Oncology Source Type: news
St. Jude and UF Proton Therapy Institute to begin proton therapy clinical trial
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(St. Jude Children's Research Hospital) St. Jude Children's Research Hospital and the University of Florida Proton Therapy Institute have formed a collaboration to provide proton therapy for St. Jude patients. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 9, 2009 Category: Global & Universal Source Type: news
St. Jude Children’s Research Hospital and UF Proton Therapy Institute to begin proton therapy clinical trial
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St. Jude Children’s Research Hospital and the University of Florida Proton Therapy Institute have formed a collaboration to provide proton therapy for St. Jude patients. The announcement follows the approval of the first clinical study to evaluate the use of proton therapy for rare brain cancers in children younger than 3 years old. (Source: St. Jude Children's Research Hospital)
Source: St. Jude Children's Research Hospital - November 9, 2009 Category: Pediatrics Source Type: organizations
Monte Carlo simulation of the neutron spectral fluence and dose equivalent for use in shielding a proton therapy vault.
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Neutron production is of principal concern when designing proton therapy vault shielding. Conventionally, neutron calculations are based on analytical methods, which do not accurately consider beam shaping components and nozzle shielding. The goal of this study was to calculate, using Monte Carlo modeling, the neutron spectral fluence and neutron dose equivalent generated by a realistic proton therapy nozzle and evaluate how these data could be used in shielding calculations. We modeled a contemporary passive scattering proton therapy nozzle in detail with the MCNPX simulation code. The neutron spectral fluence and dos...
Source: Physics in Medicine and Biology - November 7, 2009 Category: Physics Authors: Zheng Y, Newhauser W, Klein E, Low D Tags: Phys Med Biol Source Type: journals
IBA showcases low-cost proton therapy
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Belgium-based IBA (Ion Beam Applications) is hawking its two-room proton therapy solution this week at the American Society for Therapeutic Radiology and Oncology (ASTRO) meeting as a smaller, lower-cost alternative to traditional proton therapy centers. (Source: Diagnostic Imaging)
Source: Diagnostic Imaging - November 4, 2009 Category: Radiology Source Type: info
Prostate Cancer Recurrences Reduced By Adding Proton Therapy "Boost" To X-Ray Radiation Therapy
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Men who receive a "boost" of proton therapy after receiving a standard course of X-ray radiation therapy have fewer recurrences of their prostate cancer compared to men who did not receive the extra dose of proton radiation, according to a first-of-its-kind study presented November 2, 2009, at the American Society for Radiation Oncology's 51st Annual Meeting in Chicago. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 3, 2009 Category: Consumer Health News Tags: Prostate / Prostate Cancer Source Type: news
In Prostate Cancer Patients Proton Therapy Is Well-Tolerated
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Proton beam therapy can be safely delivered to men with prostate cancer and has minimal urinary and rectal side effects, according to a study presented November 2, 2009, at the American Society for Radiation Oncology's 51st Annual Meeting in Chicago. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 3, 2009 Category: Consumer Health News Tags: Prostate / Prostate Cancer Source Type: news
Reduction of low-, intermediate-risk prostate cancer recurrence observed
with proton therapy ‘boost’
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(Source: HemOncToday.com)
Source: HemOncToday.com - November 3, 2009 Category: Cancer & Oncology Source Type: info
Proton Therapy Is Well-tolerated In Prostate Cancer Patients
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Proton beam therapy can be safely delivered to men with prostate cancer and has minimal urinary and rectal side effects, according to a new study. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - November 3, 2009 Category: Science Source Type: news
Prostate cancer recurrence reduced by proton boost to radiation therapy
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Adding a round of proton therapy to photon radiotherapy reduces cancer recurrence rates in low-risk prostate cancer patients, according to the results of a randomized trial. (Source: MedWire News - Oncology)
Source: MedWire News - Oncology - November 3, 2009 Category: Cancer & Oncology Source Type: news
Prostate cancer recurrence reduced by proton boost to radiation therapy
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Adding a round of proton therapy to photon radiotherapy reduces cancer recurrence rates in low-risk prostate cancer patients, according to the results of a randomized trial. (Source: MedWire News - Prostate Cancer)
Source: MedWire News - Prostate Cancer - November 3, 2009 Category: Cancer & Oncology Source Type: news
UF study: Proton therapy safe
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Researchers at the University of Florida Proton Therapy Institute have early evidence that prostate cancer patients treated with proton therapy experience minimal urinary and rectal side effects. A recently completed study from the Institute, which houses the only proton therapy beam in the Southeast, compiled data from 212 men treated with three different clinical protocols from August 2006 to October 2007 for low, intermediate and high risk prostate cancer. The result was that 99 percent of patients receiving high dose proton therapy were free from severe treatment-related complications in the genitourinary and gastroint...
Source: bizjournals.com Health Care:Health Insurance headlines - November 2, 2009 Category: American Health Source Type: journals
UF study: Proton therapy safe
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Researchers at the University of Florida Proton Therapy Institute have early evidence that prostate cancer patients treated with proton therapy experience minimal urinary and rectal side effects. A recently completed study from the Institute, which houses the only proton therapy beam in the Southeast, compiled data from 212 men treated with three different clinical protocols from August 2006 to October 2007 for low, intermediate and high risk prostate cancer. The result was that 99 percent of patients receiving high dose proton therapy were free from severe treatment-related complications in the genitourinary and gastroint...
Source: bizjournals.com Health Care:Biotechnology headlines - November 2, 2009 Category: Biotechnology Source Type: journals
ASTRO: IBA launches a two-room proton therapy
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Ion Beam Applications (IBA) has introduced Proteus Nano, a two-room proton therapy solution at the annual meeting of the American Society for Radiology Oncology (ASTRO) in Chicago this week. (Source: Health Imaging News)
Source: Health Imaging News - November 2, 2009 Category: Radiology Tags: Latest News Source Type: news
IBA Launches MaxiPRO, An Innovative Rental Solution That Makes Proton Therapy More Accessible To Cancer Patients Everywhere
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IBA (Ion Beam Applications S.A.) announces today the launch of MaxiPRO Rental for Proton Therapy centers, which will enable significantly more hospitals and cancer centers to make Proton Therapy available for their cancer patients. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 2, 2009 Category: Consumer Health News Tags: Cancer / Oncology Source Type: news
Proton therapy is well-tolerated in prostate cancer patients
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(American Society for Radiation Oncology) Proton beam therapy can be safely delivered to men with prostate cancer and has minimal urinary and rectal side effects, according to a study presented Nov. 2, 2009, at the American Society for Radiation Oncology's 51st Annual Meeting in Chicago. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - November 2, 2009 Category: Cancer & Oncology Source Type: news
Adding proton therapy 'boost' to X-ray radiation therapy reduces prostate cancer recurrences
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(American Society for Radiation Oncology) Men who receive a "boost" of proton therapy after receiving a standard course of X-ray radiation therapy have fewer prostate cancer recurrences compared to men who did not receive the extra dose of proton radiation. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - November 2, 2009 Category: Cancer & Oncology Source Type: news
IBA releases new rental solution for proton therapy
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Ion Beam Applications (IBA) has launched a new rental solution-MaxiPRO for proton therapy centers that will enable more hospitals and cancer centers to make proton therapy available for their cancer patients. (Source: Health Imaging News)
Source: Health Imaging News - October 30, 2009 Category: Radiology Tags: Latest News Source Type: news
Fallacies in the arguments for new technology: the case of proton therapy
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In a seminal article in the Journal of Medical Ethics, Søren Holm and Tuja Takala analysed two protechnology arguments in bioethics: the hopeful principle and the automatic escalator. They showed how these arguments relate to problematic arguments such as the precautionary principle and the empirical slippery slope argument, and argued that they should be used with great caution. The present article investigates the recent debate on proton beam therapy, where the hopeful principle and the automatic escalator are identified. However, the debate reveals a series of other arguments that deserve similar caution. An anal...
Source: Journal of Medical Ethics - October 30, 2009 Category: Medical Ethics Authors: Hofmann, B Tags: Papers Source Type: journals
Proton therapy report advises caution
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The limited evidence on the comparative effectiveness of proton-beam therapy, especially in comparison to other radiation-based treatment modalities, undermines the value of this up-and-coming technology, according to a comparative effectiveness report by the Agency for Healthcare Research and Quality. (Source: Cancer Network)
Source: Cancer Network - October 30, 2009 Category: Cancer & Oncology Source Type: info
Long-term follow-up and a detailed prognostic analysis of patients with oropharyngeal cancer treated with radiotherapy
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Conclusions Primary radiotherapy was recommended for OPC patients with the lateral wall at the primary site because of good LRC. The treatment
method to the older population and T4 tumor is future tasks.
Content Type Journal ArticleCategory Original PaperDOI 10.1007/s00432-009-0700-7Authors
Natsuo Tomita, Aichi Cancer Center Hospital Department of Radiation Oncology 1-1 Kanokoden, Chikusaku Nagoya 464-8681 JapanTakeshi Kodaira, Aichi Cancer Center Hospital Department of Radiation Oncology 1-1 Kanokoden, Chikusaku Nagoya 464-8681 JapanKazuhisa Furutani, Aichi Cancer Center Hospital Department of Radiati...
Source: Journal of Cancer Research and Clinical Oncology - October 26, 2009 Category: Cancer & Oncology Tags: Journal of Cancer Research and Clinical Oncology Source Type: journals
Proton Beam Radiotherapy Versus Three-Dimensional Conformal Stereotactic Body Radiotherapy in Primary Peripheral, Early-Stage Non–Small-Cell Lung Carcinoma: A Comparative Dosimetric Analysis
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Conclusions: Single-, two-, or three-field passively or actively scanned proton therapy delivered comparable PTV dose with generally less dose to normal tissues in these hypothetic treatments. Actively scanned beam plans typically had more favorable dose characteristics to the target, lung, and other soft tissues compared with the passively scanned plans. The clinical significance of these findings remains to be determined. (Source: International Journal of Radiation Oncology * Biology * Physics)
Source: International Journal of Radiation Oncology * Biology * Physics - October 5, 2009 Category: Radiology Authors: O. Kenneth Macdonald, Jon J. Kruse, Janelle M. Miller, Yolanda I. Garces, Paul D. Brown, Robert C. Miller, Robert L. Foote Tags: Physics Contributions Source Type: journals
They came to bury proton therapy, not to praise it
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Using logic that could just as easily be applied when considering a toddler, the federal government damned proton therapy on Sept. 14 with a report that brands the cancer treatment as lacking evidence of effectiveness and safety. (Source: Diagnostic Imaging)
Source: Diagnostic Imaging - October 1, 2009 Category: Radiology Source Type: info
Todd Cancer Institute at Long Beach Memorial Medical Center and Miller Children's Hospital Granted Approval for Proton Therapy Project
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Proton Therapy Center Will Provide Southern California Cancer Patients Greater Access to Advanced Treatment Options
LONG BEACH, Calif.--(HSMN NewsFeed)--The Todd Cancer Institute (TCI) at Long Beach Memorial Medical Center (LBMMC) and Miller Childrens ... Devices, OncologyStill River Systems, proton therapy, proton beam, radiotherapy (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - September 29, 2009 Category: Pharmaceuticals Source Type: news
Advances In Radiation Therapy For Cancer: NCI Science Writers Seminar
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What Please join us for a science writers' seminar to discuss new treatments, technologies and research advances in radiation therapy for cancer. The opening of the new Roberts Proton Therapy Center at Penn Medicine, the world's largest proton therapy facility, highlights these growing trends in cancer care. A preview tour of the soon-to-open facility will wrap up the seminar. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - September 28, 2009 Category: Consumer Health News Tags: Radiology / Nuclear Medicine Source Type: news
McLaren Health, ProTom bringing proton therapy center to Michigan
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Michigan’s McLaren Health Care and ProTom International, a Texas-based health care technology company, are partnering to build a $50 million proton beam therapy center in Flint, Mich. (Source: Health Imaging News)
Source: Health Imaging News - September 24, 2009 Category: Radiology Tags: Latest News Source Type: news
Data Lacking On Proton Therapy Vs. Traditional Radiation For Cancer - AHRQ
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Particle beam radiation - also known as proton therapy - is a "promising" cancer treatment, but potential advantages over alternative radiation therapies remain unproven due to a lack of long-term comparative... (Source: OncologySTAT Latest News)
Source: OncologySTAT Latest News - September 23, 2009 Category: Cancer & Oncology Source Type: news
Still River names Jachinowski CEO
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Still River Systems, a developer of proton therapy systems for cancer treatment, has appointed Joseph K. Jachinowski as its CEO and to its board of directors. (Source: Health Imaging News)
Source: Health Imaging News - September 9, 2009 Category: Radiology Tags: Latest News Source Type: news
Prague proton therapy center deploys Elekta rad onc tools
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Elekta will provide treatment planning and oncology information management systems for the Proton Therapy Center Czech S.R.O. in Prague, Czech Republic. (Source: Health Imaging News)
Source: Health Imaging News - September 7, 2009 Category: Radiology Tags: Latest News Source Type: news
Physiologic Reactions After Proton Beam Therapy in Patients With Prostate Cancer: Significance of Urinary Autoactivation
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Conclusions: Urine is a major diffusion mediator of autoactivation after proton beam therapy. Our results indicate that physiologic factors can influence PET images of autoactivation in the context of proton beam therapy verification. (Source: International Journal of Radiation Oncology * Biology * Physics)
Source: International Journal of Radiation Oncology * Biology * Physics - September 7, 2009 Category: Radiology Authors: Masakazu Shimizu, Ryohei Sasaki, Daisuke Miyawaki, Hideki Nishimura, Yusuke Demizu, Takashi Akagi, Daisaku Suga, Hidenobu Sakamoto, Masao Murakami, Kazuro Sugimura, Yoshio Hishikawa Tags: 5th JUCTS and the 5th S. Takahashi Memorial International Joint Symposium Source Type: journals
Brain Injury After Proton Therapy or Carbon Ion Therapy for Head-and-Neck Cancer and Skull Base Tumors
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Conclusion: Particle therapies produced minimal symptomatic brain toxicities, but sequential evaluation with magnetic resonance imaging detected a greater incidence of RIBCs. Significant differences were observed in the irradiated brain volume between the brain lobes with and without RIBCs. (Source: International Journal of Radiation Oncology * Biology * Physics)
Source: International Journal of Radiation Oncology * Biology * Physics - September 7, 2009 Category: Radiology Authors: Daisuke Miyawaki, Masao Murakami, Yusuke Demizu, Ryohei Sasaki, Yasue Niwa, Kazuki Terashima, Hideki Nishimura, Yoshio Hishikawa, Kazuro Sugimura Tags: 5th JUCTS and the 5th S. Takahashi Memorial International Joint Symposium Source Type: journals
IBA Selects Elekta Software for Key Proton Therapy Site in Prague
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STOCKHOLM, Sweden--(HSMN NewsFeed)--Elekta (STO:EKTAB) will provide treatment planning and information management systems for a major Proton Therapy facility in Prague, Czech Republic. The software solutions will facilitate the highest quality of patient c... Devices, OncologyElekta, MOSAIQ, Proton Therapy, proton beam, radiotherapy (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - September 4, 2009 Category: Pharmaceuticals Source Type: news
Comparison of the effectiveness of radiotherapy with photons, protons and carbon-ions for non-small cell lung cancer: A meta-analysis.
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Conclusion: Survival rates for particle therapy were higher than those for CRT, but similar to SBRT in stage I inoperable NSCLC. Particle therapy may be more beneficial in stage III NSCLC, especially in reducing adverse events.
PMID: 19733410 [PubMed - as supplied by publisher] (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - September 2, 2009 Category: Radiology Authors: Grutters JP, Kessels AG, Pijls-Johannesma M, De Ruysscher D, Joore MA, Lambin P Tags: Radiother Oncol Source Type: journals
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Dr. Macchia raises several important issues in his commentary on our article, “Access to Information Sources and Treatment Considerations among Men with Local Stage Prostate Cancer.” First, he notes that much of what he has viewed from print, television, radio, and now the Internet is highly biased. His hunches are supported by Special Senate Committee on Aging, which convened a hearing on direct-to-consumer advertising of medical devices. At that hearing Senator Herb Kohl noted that, “As with direct-to-consumer drug ads, the FDA has raised concerns about advertising restricted [not over-the-counter] medical devices;...
Source: Urology - August 31, 2009 Category: Urology & Nephrology Authors: Scott D. Ramsey Tags: Ambulatory and Office Urology Source Type: journals
Building a compact proton accelerator
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CNET News: New research being developed at Lawrence Livermore National Laboratory, could reduce the size of proton accelerator machines from that of a football field to that of a traditional X-ray machine.
The smaller size and cost could increase the availability of proton therapy treatments.
Related Link
Electromagnetic and Thermal Simulations for the Switch Region of a Compact Proton Accelerator (Source: Physics Today News Picks)
Source: Physics Today News Picks - August 25, 2009 Category: Physics Authors: Physics Today Source Type: news
