DEXA ScanThis is an RSS file. You can use it to subscribe to this data in your favourite RSS reader, such as GoogleReader, or to display this data on your own website or blog. Subscribe to this data using MyMedWorm.Subscribe to this data using GoogleReader.Subscribe to this data using Bloglines.Subscribe to this data using MyYahoo.

This page shows you your search results in order of date.

Pages: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30

2052 records returned

Clinical audit of a dual-energy X-ray absorptiometry serviceEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Content Type Journal ArticleCategory Poster PresentationsDOI 10.1007/BF03170258Authors M. Au-Yeong, St Vincent’s University Hospital DXA Unit Dublin IrelandS. van der Kamp, St Vincent’s University Hospital DXA Unit Dublin IrelandM. J. McKenna, St Vincent’s University Hospital DXA Unit Dublin Ireland Journal Irish Journal of Medical ScienceOnline ISSN 1863-4362Print ISSN 0021-1265 Journal Volume Volume 171 Journal Issue Volume 171, Supplement 5 / October, 2002 (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - November 17, 2009 Category: Journals (General) Tags: Irish Journal of Medical Science Source Type: journals

Assessment of risk factors for osteoporosis and fractures in children with meningomyelocele.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Low-energetic fractures in MMC children may result from metabolic disturbances that are a consequence of excessive renal calcium loss or excessive fatty tissue content. PMID: 19919941 [PubMed - as supplied by publisher] (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - November 16, 2009 Category: Biomedical Science Authors: Okurowska-Zawada B, Konstantynowicz J, Kułak W, Kaczmarski M, Piotrowska-Jastrzębska J, Sienkiewicz D, Paszko-Patej G Tags: Adv Med Sci Source Type: journals

Muscle hypertrophy and increased expression of leptin receptors in the musculus triceps brachii of the dominant arm in professional tennis playersEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract In rodents, endurance training increases leptin sensitivity in skeletal muscle; however, little is known about the effects of exercise on the leptin signalling system in human skeletal muscle. Thus, to determine whether chronic muscle loading increases leptin receptor (OB-R170) protein expression, body composition dual-energy X-ray absorptiometry was assessed in nine professional male tennis players (24 ± 4 years old) and muscle biopsies were obtained from the dominant (DTB) and non-dominant (NDTB) arm triceps brachii (TB), and also from the right vastus lateralis (VL). In each biops...
Source: European Journal of Applied Physiology - November 14, 2009 Category: Physiology Tags: European Journal of Applied Physiology Source Type: journals

Frequency of zoledronic acid to prevent further bone loss in osteoporotic patients undergoing androgen deprivation therapy for prostate cancerEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
To evaluate the efficacy of zoledronic acid (ZA) in osteoporotic patients with prostate cancer receiving either luteinizing hormone-releasing hormone agonists (LHRHA, which accelerate bone loss) or bicalutamide (which preserves bone mineral density, BMD) as androgen-deprivation therapy is the mainstay of treatment for advanced prostate cancer, and many patients are osteoporotic at presentation, with others becoming so on treatment. Fifty-eight osteoporotic men with non-metastatic prostate cancer were followed for 3 years. Patients were randomly assigned to receive either LHRHA (29) or bicalutamide (29). All received 4 mg Z...
Source: BJU International - November 13, 2009 Category: Urology & Nephrology Authors: Vivek K. Wadhwa, Robin Weston, Nigel J. Parr Source Type: journals

Prevalence and Predictors of Osteoporosis Risk in Orthopaedic Patients.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: Low bone mineral density is common among orthopaedic outpatients. Age, female gender, smoking, wrist fractures, and spinal deformities are independent risk factors for osteoporosis. We present a probability model designed to assist orthopaedic surgeons in identifying high-risk patients and initiating adequate preventative measures. LEVEL OF EVIDENCE: Level I, diagnostic study. See Guidelines for Authors for a complete description of levels of evidence. PMID: 19911243 [PubMed - as supplied by publisher] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - November 13, 2009 Category: Orthopaedics Authors: Rozental TD, Shah J, Chacko AT, Zurakowski D Tags: Clin Orthop Relat Res Source Type: journals

Insulin Resistance in Adolescents with Type 1 Diabetes and Its Relationship to Cardiovascular Function.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: T1D youth demonstrated IR, impaired functional exercise capacity and cardiovascular dysfunction. The phenotype of IR in T1D youth was unique, suggesting a pathophysiology that is different from T2D, yet may adversely affect long-term cardiovascular outcomes. PMID: 19915016 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism)
Source: The Journal of Clinical Endocrinology and Metabolism - November 13, 2009 Category: Endocrinology Authors: Nadeau KJ, Regensteiner JG, Bauer TA, Brown MS, Dorosz JL, Hull A, Zeitler P, Draznin B, Reusch JE Tags: J Clin Endocrinol Metab Source Type: journals

Bone loss in patients with active early rheumatoid arthritis: infliximab and methotrexate compared with methotrexate treatment alone. Explorative analysis from a 12-month randomised, double-blind, placebo-controlled studyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: This study provides strong evidence of a causal link between inflammation and bone loss in RA. The anti-inflammatory effect of infliximab was potent enough to arrest inflammatory bone loss at the hip but not at the spine and hand. (Source: Annals of the Rheumatic Diseases)
Source: Annals of the Rheumatic Diseases - November 12, 2009 Category: Rheumatology Authors: Haugeberg, G, Conaghan, P G, Quinn, M, Emery, P Tags: Immunology (including allergy), Inflammation, Biological agents, Connective tissue disease, Degenerative joint disease, Drugs: musculoskeletal and joint diseases, Musculoskeletal syndromes, Rheumatoid arthritis Clinical and epidemiological research Source Type: journals

Psychological symptoms and insulin sensitivity in adolescentsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: As has been described for adults, depressive symptoms are associated with low insulin sensitivity among healthy adolescents. Further experimental and prospective studies are required to determine the directionality of this link. (Source: Pediatric Diabetes)
Source: Pediatric Diabetes - November 12, 2009 Category: Endocrinology Authors: Lauren B Shomaker, Marian Tanofsky-Kraff, Deborah Young-Hyman, Joan C Han, Lisa B Yanoff, Sheila M Brady, Susan Z Yanovski, Jack A Yanovski Source Type: journals

Time-course of exercise and its association with 12-month bone changesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Background: Exercise has been shown to have positive effects on bone density and strength. However, knowledge of the time-course of exercise and bone changes is scarce due to lack of methods to quantify and qualify daily physical activity in long-term. The aim was to evaluate the association between exercise intensity at 3, 6 and 12 month intervals and 12-month changes in upper femur areal bone mineral density (aBMD) and mid-femur geometry in healthy premenopausal women. Methods: Physical activity was continuously assessed with a waist-worn accelerometer in 35 healthy women (35-40 years) participating in progressive high-i...
Source: BMC Musculoskeletal Disorders - November 12, 2009 Category: Orthopaedics Authors: Riikka AholaRaija KorpelainenAki VainionpaaJuhani LeppaluotoTimo Jamsa Source Type: journals

T-Scores and Z-ScoresEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract Bone mineral density (BMD) can be measured by a variety of techniques at several skeletal sites. Once measured, the manufacturers’ software uses the BMD to calculate a T-score and/or Z-score. Both T-scores and Z-scores are derived by comparison to a reference population on a standard deviation scale. The recommended reference group for the T-score is a young gender-matched population at peak bone mass, while the Z-score should be derived from an age-matched reference population. T-scores and Z-scores are widely quoted in scientific publications on osteoporosis and BMD studies, and are the values use...
Source: Clinical Reviews in Bone and Mineral Metabolism - November 10, 2009 Category: Internal Medicine Tags: Clinical Reviews in Bone and Mineral Metabolism Source Type: journals

Bone mineral density, body composition, and food intake of adolescent runway models.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: Although no association was found between BMD, BMI, and intake of nutrients that are important for the bone mineralization process, inadequacies of food intake have an adverse influence on the acquisition of bone mass, which is more effective at this stage of life. PMID: 19904480 [PubMed - as supplied by publisher] (Source: Jornal de Pediatria)
Source: Jornal de Pediatria - November 10, 2009 Category: Pediatrics Authors: Rodrigues AM, Cintra IP, Santos LC, Martini LA, Mello MT, Fisberg M Tags: J Pediatr (Rio J) Source Type: journals

Full fat milk 'link to BMI'Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion The finding that full-fat milk is associated with lower children’s BMI is unexpected, and the researcher herself was surprised by the results. Two theories are put forward: either the children who drink full-fat milk have less snacks and sugary drinks, or their diets are generally healthier with fewer total calories. Both are plausible, but the study was in a relatively small group of children, and there are several possible confounding factors, including socio economic factors, which could have caused the results. Overall, this study raises more questions than it answers and in the tradition of a PhD thesis w...
Source: NHS News Feed - November 9, 2009 Category: Consumer Health News Tags: Pregnancy/child Source Type: news

Full-fat milk 'link to BMI'Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion The finding that full-fat milk is associated with lower children’s BMI is unexpected, and the researcher herself was surprised by the results. Two theories are put forward: either the children who drink full-fat milk have fewer snacks and sugary drinks, or their diets are generally healthier with fewer total calories. Both are plausible, but the study was in a relatively small group of children, and there are several possible confounding factors, including socio-economic factors, which could have caused the results. Overall, this study raises more questions than it answers and, in the tradition of a PhD thesis...
Source: NHS News Feed - November 9, 2009 Category: Consumer Health News Tags: Pregnancy/child Source Type: news

Adolescent exercise associated with long-term superior measures of bone geometry: a cross-sectional DXA and MRI studyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Adolescent weight-bearing exercise exerts preservational effects on femoral mid-diaphyseal size and shape, while DXA-measured BMC effectively identified the same tendency. Weight-bearing exercise in youth affects bone, and these effects may be preserved as BMC, geometric and structural advantages even after 40 years. (Source: British Journal of Sports Medicine)
Source: British Journal of Sports Medicine - November 9, 2009 Category: Sports Medicine Authors: Kato, T, Yamashita, T, Mizutani, S, Honda, A, Matumoto, M, Umemura, Y Tags: Original articles Source Type: journals

Musculoskeletal manifestations in patients with malignant diseaseEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract To detect and describe the incidence of musculoskeletal manifestations in different malignant diseases as well as their relation to the treatment received whether by chemotherapy or radiation therapy. Sixty patients with different malignant diseases were included in this study, 45 with solid tumors and 15 patients with hematological malignancy. The mean age was 46.55 ± 11.04 years and the mean disease duration was 2 ± 0.75 years. The patients were fully examined for any rheumatologic involvement, laboratory investigations were performed as well as dual energy X-ray absorptiometry...
Source: Clinical Rheumatology - November 7, 2009 Category: Rheumatology Tags: Clinical Rheumatology Source Type: journals

Bone Mineral Density and Serum Levels of Soluble Tumor Necrosis Factors, Estradiol, and Osteoprotegerin in Postmenopausal Women with Cirrhosis after Viral Hepatitis.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: This study shows that bone mass and bone resorption rates do not differ between postmenopausal women with viral cirrhosis and healthy postmenopausal controls and suggests that viral cirrhosis does not appear to increase the risk of osteoporosis in these women. High serum estradiol and OPG concentrations may contribute to preventing the bone loss associated with viral cirrhosis in postmenopausal women. PMID: 19897681 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism)
Source: The Journal of Clinical Endocrinology and Metabolism - November 6, 2009 Category: Endocrinology Authors: González-Calvin JL, Mundi JL, Casado-Caballero FJ, Abadia AC, Martin-Ibañez JJ Tags: J Clin Endocrinol Metab Source Type: journals

Vitamin D insufficiency in a large female SLE cohort.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In conclusion, sub-optimal vitamin D status is common in women with systemic lupus erythematosus and is related to season, cumulative glucocorticoid dose, and serum creatinine. PMID: 19897520 [PubMed - as supplied by publisher] (Source: Lupus)
Source: Lupus - November 6, 2009 Category: Rheumatology Authors: Toloza SM, Cole DE, Gladman DD, Ibañez D, Urowitz MB Tags: Lupus Source Type: journals

Sex Differences in Regional Body Fat Distribution From Pre- to Postpuberty.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The objective of this study was to determine the timing and magnitude of sex differences in regional adiposity from early childhood to young adulthood. Regional fat distribution was measured using dual-energy X-ray absorptiometry (trunk and extremity fat using automatic default regions and waist and hip fat using manual analysis) in 1,009 predominantly white participants aged 5-29 years. Subjects were divided into pre (Tanner stage 1), early (Tanner stages 2-3), late (Tanner stages 4-5), and post (males >/=20 years and females >/=18 years) pubertal groups. Sexual dimorphism in trunk fat (adjusted for extremity fat) w...
Source: Obesity - November 5, 2009 Category: Eating Disorders and Weight Management Authors: Taylor RW, Grant AM, Williams SM, Goulding A Tags: Obesity (Silver Spring) Source Type: journals

Dual energy X-ray absorptiometry analysis contributes to the prediction of hip osteoarthritis progressionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The objective was to determine if structural bone parameters obtained from dual energy X-ray absorptiometry (DXA) contribute to the prediction of progression of hip osteoarthritis (OA) and to test if the difference between the most affected (OA) hip and the contralateral hip adds to this prediction. Methods: The study group involves a prospective cohort of 189 patients that met the ACR classification criteria for hip osteoarthritis. Progression was defined as 20% joint space narrowing or total hip replacement within a two years follow up. Software was developed to calculate geometrical aspects and bone mineral density (BMD...
Source: BioMed Central - November 2, 2009 Category: Journals (General) Authors: Martha Castano BetancourtJacqueline Van der LindenFernando RivadeneiraRianne RozendaalSita Bierma-ZeinstraHarrie WeinansJan Waarsing Source Type: journals

Comparison of body fatness measurements by near-infrared reactance and dual-energy X-ray absorptiometry in normal-weight and obese black and white women.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In conclusion, although there was a significant relationship between NIR- and DXA-derived BF %, NIR under-predicted BF % in normal-weight and obese black South African women compared to DXA, but to a greater extent in subjects with very high levels of adiposity (>45 %). The results of single-site NIR as a measure of BF % should therefore be interpreted with caution, particularly in women of African descent and in those with very high levels of adiposity. PMID: 19878617 [PubMed - as supplied by publisher] (Source: The British Journal of Nutrition)
Source: The British Journal of Nutrition - November 2, 2009 Category: Nutrition Authors: Jennings CL, Micklesfield LK, Lambert MI, Lambert EV, Collins M, Goedecke JH Tags: Br J Nutr Source Type: journals

Measurement of Body Composition in Burned Children: Is There a Gold Standard?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: DEXA can provide a sufficiently accurate determination of LBM and changes in body composition, but a correction factor must be included for older children and adolescents with more LBM. DEXA scans are easier, cheaper, and less stressful for the patient, and this method should be used rather than the K count. (JPEN J Parenter Enteral Nutr. XXXX;xx:xx-xx). PMID: 19884353 [PubMed - as supplied by publisher] (Source: JPEN Journal Of Parenteral And Enteral Nutrition)
Source: JPEN Journal Of Parenteral And Enteral Nutrition - November 2, 2009 Category: Nutrition Authors: Branski LK, Norbury WB, Herndon DN, Chinkes DL, Cochran A, Suman O, Benjamin D, Jeschke MG Tags: JPEN J Parenter Enteral Nutr Source Type: journals

A case-control study on risk factors of osteoporosisin patients with Crohn's disease.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: The highest osteoporosis risk was seen in patients with a cumulative 10 - 35 g corticosteroid dose and could be due to both steroid inefficiency in reducing Crohn's disease inflammation as well as the cumulative drug dose and it's adverse effect on patients. PMID: 19877750 [PubMed - in process] (Source: Archives of Iranian Medicine)
Source: Archives of Iranian Medicine - November 1, 2009 Category: Middle East Health Authors: Vahedi H, Momtahen S, Olfati G, Abtahi A, Hosseini S, Kazzazi AS, Khademi H, Rashtak S, Khaleghnejad R, Tabrizian T, Hamidi Z, Nouraie M, Malekzadeh F, Merat S, Nasseri-Moghaddam S, Sotoudehmanesh R, Larijani B Tags: Arch Iran Med Source Type: journals

Bone Density of Ambulatory Adult Patients Receiving Long-term Anticonvulsant Drug Therapy.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: Our results suggest that maintenance therapy with antiepileptic drugs may decrease bone mass. These data also suggest a higher bone turnover rate in those receiving anticonvulsants. PMID: 19877746 [PubMed - in process] (Source: Archives of Iranian Medicine)
Source: Archives of Iranian Medicine - November 1, 2009 Category: Middle East Health Authors: Ashjazadeh N, Zamani A, Pourjafar M, Omrani GR Tags: Arch Iran Med Source Type: journals

Drug packaging and delivery using perfluorocarbon nanoparticles for targeted inhibition of vascular smooth muscle cells.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: The results collectively suggest that PFC nanoparticles will be beneficial for targeted drug delivery because of the sustained drug release and effective inhibition of SMC proliferation and migration. PMID: 19890365 [PubMed - in process] (Source: Acta Pharmacologica Sinica)
Source: Acta Pharmacologica Sinica - November 1, 2009 Category: Drugs & Pharmacology Authors: Zhou ZX, Zhang BG, Zhang H, Huang XZ, Hu YL, Sun L, Wang XM, Zhang JW Tags: Acta Pharmacol Sin Source Type: journals

DXA Self-Scheduling Results in More ScansEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
DENVER — Women who are encouraged to self-schedule dual-energy x-ray absorptiometry scans via mailed brochures and letters undergo more scans than do those in usual practice, but this is still not a silver bullet strategy for identifying women with osteoporosis. (Source: Rheumatology News)
Source: Rheumatology News - November 1, 2009 Category: Rheumatology Authors: KERRI WACHTER Tags: Across Specialties Source Type: journals

Immune changes in post-menopausal osteoporosis: the Immunos studyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions Our results suggest that, regardless of age and estrogen status, postmenopausal OP is associated with immune changes, highlighting a possible role of IFN-γ in the pathophysiology of OP and reporting, for the first time, changes in several B lymphocyte populations. These alterations may reflect the frailty observed after fracture, providing new insight into the mechanisms of morbidity and mortality associated with OP fractures. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-009-1018-7Authors V. Breuil, CHU de Nice, Hôpital l’Archet Service de Rhumatologie Route...
Source: Osteoporosis International - October 30, 2009 Category: Orthopaedics Tags: Osteoporosis International Source Type: journals

Long term effects of normal calcium–high fat diets on body composition and bone mass, in ratsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Obesity and osteoporosis share a common cell progenitor. High adipocyte count in bone marrow is directly related to bone loss, as fat cells replace osteoblasts. We investigated long-term intake effect of normal calcium (Ca) diets—with different fat content—on body composition and bone mineral content (BMC), in healthy rats. At weaning (21 days), female Wistar rats (n=30) were randomly assigned one of the following 3 groups (n=10 each). G1 was sacrificed in order to get basal values (P0); G2 and G3 were fed ad libitum one of the two isocaloric diets (A; fat=7% wt./wt. or B; fat=15% wt./wt.). Mothers (M1A and M1B) were ...
Source: Bone - October 29, 2009 Category: Orthopaedics Authors: E. Hernández, C. Suarez, A. Ferreira Monteiro, P. Rodriguez, M. Gonzáles-Chaves, G. Pellegrini, R. Orzuza, S. Zeni, S. Friedman Source Type: journals

Does a new source of monounsaturated fatty acids improve lipid profile and body mineral content in nutritional hypercholesterolemia?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In recent years, food industries has demonstrated increased interest in food rich in high-oleic-acid sunflower oil (HOSO, ω9) made from sunflower oil (SO, ω6) to substitute trans-fatty acids. Diets containing HOSO are often promoted to treat nutritional hypercholesterolemia (NHC); however, there are limited data about the effect of this new source of monounsaturated fatty acids (MUFA; HOSO, ω9) on lipid profile and body mineral content (BMC). We performed the study in an experimental model of NH. Weaning male Wistar rats (n=34) were randomly assigned to one of 5 groups (C, Control; E, Experimental). All groups underwent...
Source: Bone - October 29, 2009 Category: Orthopaedics Authors: E.V. Macri, N. Juiz, C. Ramos, M.M. Gonzales Chaves, C. Gamba, V. Zago, L. Scherier, P. Rodriguez, S. Zeni, S. Friedman Source Type: journals

Genotypes of the vitamin D and the estrogen receptors in three osteoporotic members of a familyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
There is a relationship between some polymorphic sites of the vitamin D receptor and the estrogen receptor genes, and bone mineral density (BMD). The goal of this report is to show this relationship in three members of one family. Patient PC is a 28-year-old male, BMI 19.2 kg/m2. He smokes 10 cigarettes/d. He sustained five peripheral fractures between the ages of 8 and 20 years. When he was 23, radiographs taken for a pre-occupational examination showed osteopenia. Bone densitometry (DXA) showed T-scores of −3.3 (spine) and −3.4 (femur). Causes of secondary osteoporosis were ruled out. Treatment with oral strontium r...
Source: Bone - October 29, 2009 Category: Orthopaedics Authors: M. Echecury, E. Nebel, A. Pérez, G. Picotto, N. Tolosa de Talamoni, A. Sánchez Source Type: journals

Low fat-free soft mass in legs of Duchenne's disease carriersEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Duchenne/Becker muscular dystrophy (DMD/BMD) is an X-linked disease caused by mutations in the dystrophin gene at Xp21 and therefore affects males. In these males, lower bone mineral content and lean mass, and higher fat mass, have been found by several methods, including dual x-ray absorptiometry (DXA). While women are carriers, subtle biochemical and structural alterations have been reported in them (e.g., elevation of serum creatine phosphokinase and muscle weakness). Aiming to assess whether DXA might be used for screening women with suspected DMD/BMD carrier status, whole body scans (GE Lunar Prodigy) were performed i...
Source: Bone - October 29, 2009 Category: Orthopaedics Authors: F.D. Saraví, A. Mampel, M.I. Echeverría, A.L. Vargas Source Type: journals

Calcium nutritional status and its relation to oral health, exercise, and lifestyle in a group of students ranging 18 to 34 years oldEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: Based on the results obtained, there is a high Ca deficiency in the studied group with dietary and lifestyle habits that would affect oral health and, in the future, skeleton status. A nutrition education would benefit the nutritional status and would improve life quality of subjects. (Source: Bone)
Source: Bone - October 29, 2009 Category: Orthopaedics Authors: O. Antonenko, G.G. Pellegrini, G. Brito, J. Somoza, S.N. Zeni Source Type: journals

Decrease in femoral neck (FN) bone mineral density (BMD) after menopause: Relative importance of changes in bone mineral content (BMC) and area (A)Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Bone mineral density (BMD) of the femoral neck (FN) suffers a rapid loss during the first 5–7 years after menopause. We investigated the changes of BMC and A (both determine BMD) along life in women after menopause. Materials and methods: In a cross-sectional study, BMD, BMC, and A of left FN were measured with DXA (Lunar Prodigy) in 191 women which required bone routine evaluation. Pearson regression test was used to evaluate the influence of age on the three variables on the whole population (WP) and group (G) 1 (Source: Bone)
Source: Bone - October 29, 2009 Category: Orthopaedics Authors: H. Claus Hermberg, M. Lozano, M. Rey, M. Pozzo Source Type: journals

Dual hip densitometry: Analysis of densitometric and geometrical differencesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Bone mineral density (BMD) of both femurs is often requested in spite of that World Health Organization does not recommend it for assessment of densitometric categories. We used data of patients who realized dual femur densitometry to analyze the variations in densitometric and geometrical properties between both hips. Materials and methods: BMD was measured with DXA (Lunar Prodigy). BMD (mg/cm2) disparities of femoral neck and total hip were analyzed by Z score. Differences in BMD, bone mineral content (BMC, g), area (A, cm2), cross-sectional moment of inertia (CSMI, mm4), hip axis length (HAL, mm), hip axis/diaphysis axi...
Source: Bone - October 29, 2009 Category: Orthopaedics Authors: H. Claus Hermberg, M. Lozano, M. Rey, M. Pozzo Source Type: journals

Prevalence of deficit of vitamin D in patients with overweight and obesityEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Vitamin D (VD) is essential for bone and muscle health. Obesity is a risk factor for hypovitaminosis D because obese patients often have less exposure to UV radiation either by making physical activity less or the possible kidnapping of VD by the adipocytes. This determined lower synthesis of 25(OH) VD due to a negative feedback with 1.25(OH)2D and PTH. A recent survey shows that 10.6% of people between 20 and 49 years were overweight and obese and have VD values ≥36 ng/ml. Objective: To establish the prevalence of VD deficiency in postmenopausal (PM), osteoporotic, overweight, and obese women. Materials and methods: 39...
Source: Bone - October 29, 2009 Category: Orthopaedics Authors: M. Larrroude, M. Moggia, R. Díaz, M. Pérez Sainz, G. Macías, Z. Man Source Type: journals

Experimental models of nutritional deficiencies and hormonal status that influence bone massEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Elderly people often had a low food intake and sun exposure which could contribute to the high prevalence of osteopenia and fracture risk observed in this population. To evaluate the influence of the low protein intake and/or vitamin D (vit. D) status in the pathogenesis of osteoporosis, we developed the present experimental models. Wistar rats (300±50 g) were OVX (n=20) or SHAM operated (n=20). During 15 days after surgery, all rats were fed a diet containing 15% protein and 200 IU% of vit. D. Then, rats were divided into 5 groups, fed a specified diet during an additional period of 45 days: G1: SHAM+15% casein and 2...
Source: Bone - October 29, 2009 Category: Orthopaedics Authors: C. Marotte, M.M.S. Gonzales Chaves, G.G. Pellegrini, P. Mandalunis, S.M. Friedman, S.N. Zeni Source Type: journals

Antitumor necrotic factor agent promotes BMP-2-induced ectopic bone formationEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract Etanercept (ETN), which is a recombinant human soluble tumor necrosis factor (TNF) receptor that inhibits TNF activity, is effective in the treatment of rheumatoid arthritis. We investigated the effect of ETN on recombinant human bone morphogenetic protein-2 (rhBMP-2)-induced ectopic bone formation in vivo. A block copolymer composed of poly-d,l-lactic acid with random insertion of p-dioxanone and polyethylene glycol (PLA–DX–PEG polymer) was used as the delivery system. Polymer discs (6 mm, 30 mg) containing 5 μg rhBMP-2 were implanted into the left dorsal muscle pouch of mice (n&...
Source: Journal of Bone and Mineral Metabolism - October 29, 2009 Category: Orthopaedics Tags: Journal of Bone and Mineral Metabolism Source Type: journals

Validity of Bioelectrical Impedance Analysis to Estimate Body Composition Changes After Bariatric Surgery in Premenopausal Morbidly WomenEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract In obese patients, subtle variations of the hydration of soft tissues can propagate errors in bioelectrical impedance analysis (BIA) measures of body composition. Bioelectrical impedance vector analysis (BIVA) is a useful method to evaluate tissue hydration. Laparoscopic adjustable gastric banding (LAGB) is a purely restrictive bariatric surgical procedure resulting in lower fat-free mass (FFM) loss than other malabsorptive or mixed intervention. The aim of this study was to evaluate the 6- and 12-month changes in body composition in a homogeneous group of premenopausal morbidly obese women treated ...
Source: Obesity Surgery - October 27, 2009 Category: Surgery Tags: Obesity Surgery Source Type: journals

Cadmium, follicle-stimulating hormone, and effects on bone in women age 42-60 years, NHANES III.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: Long-term cadmium exposure at environmental levels is associated with increased serum FSH, and both FSH and UCd are associated with bone loss, in US women aged 42-60 years. PMID: 19875111 [PubMed - as supplied by publisher] (Source: Environmental Research)
Source: Environmental Research - October 27, 2009 Category: Environmental Health Authors: Gallagher CM, Moonga BS, Kovach JS Tags: Environ Res Source Type: journals

Does standardized BMD still remove differences between Hologic and GE-Lunar state-of-the-art DXA systems?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions The sBMD values were shown to be equivalent within 1.0% for hip but were significantly different for spine on the two systems. Biases may persist in pooled sBMD data from different manufacturers, and further study is necessary to determine the cause. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-009-1062-3Authors B. Fan, University of California San Francisco Department of Radiology and Biomedical Imaging San Francisco CA USAY. Lu, University of California San Francisco Department of Radiology and Biomedical Imaging San Francisco CA USAH. Genant, University of Cali...
Source: Osteoporosis International - October 26, 2009 Category: Orthopaedics Tags: Osteoporosis International Source Type: journals

Automated 3D trabecular bone structure analysis of the proximal femur—prediction of biomechanical strength by CT and DXAEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion A combination of bone mass (DXA) and structure parameters of the trabecular bone (linear and nonlinear, global and local) most accurately predicted absolute and relative femoral bone strength. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-009-1090-zAuthors T. Baum, Technische Universität München Institut für Röntgendiagnostik, Klinikum Rechts der Isar Ismaninger Str. 22 81675 Munich GermanyJ. Carballido-Gamio, University of California, San Francisco Musculoskeletal and Quantitative Imaging Research, Department of Radiology 185 Berry Street, Suite 350 San Francis...
Source: Osteoporosis International - October 26, 2009 Category: Orthopaedics Tags: Osteoporosis International Source Type: journals

Aluminum Exposure From Parenteral Nutrition in Preterm Infants: Bone Health at 15-Year Follow-upEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: Neonates who are exposed to parenteral aluminum may have reduced lumbar spine and hip bone mass during adolescence, potential risk factors for later osteoporosis and hip fracture. These findings need confirmation in larger, more detailed studies. Nevertheless, given our previous finding of adverse developmental outcome in these individuals and the sizeable number of contemporary infants who undergo intensive neonatal care and are still exposed to aluminum via parenteral feeding solutions, the potential adverse long-term consequences of early aluminum exposure now deserve renewed attention. (Source: PEDIATRICS)
Source: PEDIATRICS - October 26, 2009 Category: Pediatrics Authors: Fewtrell, M. S., Bishop, N. J., Edmonds, C. J., Isaacs, E. B., Lucas, A. Tags: Therapeutics & Toxicology ARTICLES Source Type: journals

Osteoporosis, the risk of vertebral fracture, and periodontal disease in an elderly group in Mexico CityEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: Periodontitis extent was associated with osteoporosis, and tooth loss with fracture risk. (Source: Gerodontology)
Source: Gerodontology - October 26, 2009 Category: Dentistry Authors: Diana E. Moedano, Maria E. Irigoyen, Aida Borges-Yáñez, Ismael Flores-Sánchez, Ricardo C. Rotter Source Type: journals

Clinical research Evaluation of bone mineral density and bone turnover markers in Egyptian children with juvenile rheumatoid arthritisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: JRA patients had lower BMD, higher frequency of low BMD (more prominent in the femoral neck) and higher OPG and RANKL levels compared with healthy children; suggesting that they may be at risk of developing premature osteoporosis and fractures later in life. (Source: Articles of Archives of Medical Science - TERMEDIA publishing house)
Source: Articles of Archives of Medical Science - TERMEDIA publishing house - October 22, 2009 Category: Journals (General) Source Type: journals

Traditional Anthropometric Parameters Still Predict Metabolic Disorders in Women With Severe Obesity.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
It is well established that fat distribution rather than the total quantity of fat is the major determinant of cardiovascular risk in overweight subjects. However, it is not known whether the concept of fat distribution still makes sense in severely obese subjects. Particularly, the role of visceral fat accumulation and/or of adipocyte hypertrophy in insulin resistance (IR) has not been studied in this population. Therefore, the aim of this study was to clarify the determinants of metabolic disorders in severely obese women. We performed a cross-sectional study in 237 severely obese women (BMI >35 kg/m(2)). We asses...
Source: Obesity - October 22, 2009 Category: Eating Disorders and Weight Management Authors: Ledoux S, Coupaye M, Essig M, Msika S, Roy C, Queguiner I, Clerici C, Larger E Tags: Obesity (Silver Spring) Source Type: journals

Identifying Metabolically Healthy but Obese Individuals in Sedentary Postmenopausal Women.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In conclusion, the present study shows variations in body composition and metabolic profile based on the methods studied to define the MHO phenotype. Therefore, an expert consensus may be needed to standardize the identification of MHO individuals. PMID: 19851302 [PubMed - as supplied by publisher] (Source: Obesity)
Source: Obesity - October 22, 2009 Category: Eating Disorders and Weight Management Authors: Messier V, Karelis AD, Prud'homme D, Primeau V, Brochu M, Rabasa-Lhoret R Tags: Obesity (Silver Spring) Source Type: journals

Preadipocyte Factor-1 Is Associated with Marrow Adiposity and Bone Mineral Density in Women with Anorexia Nervosa.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Pref-1 is elevated in AN. Pref-1, IGF-I, IGF-BP2 and leptin are associated with marrow adiposity and BMD. PMID: 19850693 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism)
Source: The Journal of Clinical Endocrinology and Metabolism - October 22, 2009 Category: Endocrinology Authors: Fazeli PK, Bredella MA, Misra M, Meenaghan E, Rosen CJ, Clemmons DR, Breggia A, Miller KK, Klibanski A Tags: J Clin Endocrinol Metab Source Type: journals

A rosiglitazone-induced increase in adiponectin does not improve glucose metabolism in HIV-infected patients with overt lipoatrophyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
HIV-infected patients on antiretroviral therapy frequently develop changes in body fat distribution and disturbances in glucose metabolism, associated with reduced adiponectin levels. Because adiponectin, principally the high-molecular-weight (HMW) form, has insulin-sensitizing properties, we investigated the effects of an increase in adiponectin on glucose metabolism in HIV-lipodystrophy. In this randomized, double-blind, placebo-controlled trial, we included HIV-1-infected patients with severe lipoatrophy, with an undetectable viral load and who had received neither protease inhibitors nor stavudine for ≥6 mo. Patient...
Source: AJP: Endocrinology and Metabolism - October 21, 2009 Category: Endocrinology Authors: Blumer, R. M. E., van der Valk, M., Ackermans, M., Endert, E., Serlie, M. J., Reiss, P., Sauerwein, H. P. Tags: Articles Source Type: journals

The relationships among bone health, insulin-like growth factor-1 and sex hormones in adolescent female athletesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract The aim of this study was to determine the relationships of bone mineral density (BMD) and content (BMC) with insulin-like growth factor-1 (IGF-1), IGF-binding protein-3 (IGFBP-3) and estradiol in pubertal female athletes. The participants were 170 healthy adolescent girls (13–15 years) who participated in competitive extramural athletic programs, i.e., sports games (n = 49), track sprinting (n = 24), rhythmic gymnastics (n = 23), swimming (n = 24) and cross-country skiing (n = 17). The control group (n = 33) consisted of girls who to...
Source: Journal of Bone and Mineral Metabolism - October 21, 2009 Category: Orthopaedics Tags: Journal of Bone and Mineral Metabolism Source Type: journals

Neonatal Exendin-4 Treatment Reduces Oxidative Stress and Prevents Hepatic Insulin Resistance in Intrauterine Growth Retarded Rats.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Intrauterine growth retardation (IUGR) has been linked to the development of type 2 diabetes in adulthood. We have developed an IUGR model in the rat whereby the animals develop diabetes later in life. Previous studies demonstrate that administration of the long-acting glucagon-like-peptide-1 agonist, Exendin-4, during the neonatal period prevents the development of diabetes in IUGR rats. IUGR animals exhibit hepatic insulin resistance early in life (prior to the onset of hyperglycemia), characterized by blunted suppression of hepatic glucose production (HGP) in response to insulin. Basal HGP is also significantly high...
Source: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology - October 20, 2009 Category: Physiology Authors: Raab EL, Vuguin PM, Stoffers DA, Simmons RA Tags: Am J Physiol Regul Integr Comp Physiol Source Type: journals

Collaborative meta-analysis: associations of 150 candidate genes with osteoporosis and osteoporotic fracture.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: In this large-scale collaborative genome-wide meta-analysis, 9 of 150 candidate genes were associated with regulation of BMD, 4 of which also significantly affected risk for fracture. However, most candidate genes had no consistent association with BMD. PMID: 19841454 [PubMed - in process] (Source: Annals of Internal Medicine)
Source: Annals of Internal Medicine - October 19, 2009 Category: Internal Medicine Authors: Richards JB, Kavvoura FK, Rivadeneira F, Styrkársdóttir U, Estrada K, Halldórsson BV, Hsu YH, Zillikens MC, Wilson SG, Mullin BH, Amin N, Aulchenko YS, Cupples LA, Deloukas P, Demissie S, Hofman A, Kong A, Karasik D, van Meurs JB, Oostra BA Tags: Ann Intern Med Source Type: journals