Yellow Fever Vaccination
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WHO To Launch Yellow Fever Vaccination Campaign In West Africa
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The WHO on Tuesday announced it would lead a week-long, multi-country vaccination campaign in Africa next week to protect those "deemed at highest risk from yellow fever," Reuters reports. The vaccination drive will target nearly 12 million Africans living in Benin, Liberia and Sierra Leone - all countries at high risk of yellow fever outbreaks (Nebehay/MacInnis, 11/17). (Source: Tropical Diseases News From Medical News Today)
Source: Tropical Diseases News From Medical News Today - November 19, 2009 Category: Tropical Medicine Tags: Tropical Diseases Source Type: news
WHO To Launch Yellow Fever Vaccination Campaign In West Africa
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The WHO on Tuesday announced it would lead a week-long, multi-country vaccination campaign in Africa next week to protect those "deemed at highest risk from yellow fever," Reuters reports. The vaccination drive will target nearly 12 million Africans living in Benin, Liberia and Sierra Leone - all countries at high risk of yellow fever outbreaks (Nebehay/MacInnis, 11/17). (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 19, 2009 Category: Consumer Health News Tags: Tropical Diseases Source Type: news
Africa: The Nation, Others to Benefit From WHO Yellow Fever Vaccination
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The largest-ever mass vaccination campaign to protect people from yellow fever disease will begin next week across three West African countries, the World Health Organisation (WHO) has announced. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - November 19, 2009 Category: African Health Source Type: news
Viruses within the Flaviviridae Decrease CD4 Expression and Inhibit HIV Replication in Human CD4+ Cells.
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Viral infections alter host cell homeostasis and this may lead to immune evasion and/or interfere with the replication of other microbes in coinfected hosts. Two flaviviruses are associated with a reduction in HIV replication or improved survival in HIV-infected people (dengue virus (DV) and GB virus type C (GBV-C)). GBV-C infection and expression of the GBV-C nonstructural protein 5A (NS5A) and the DV NS5 protein in CD4(+) T cells inhibit HIV replication in vitro. To determine whether the inhibitory effect on HIV replication is conserved among other flaviviruses and to characterize mechanism(s) of HIV inhibition, the ...
Source: Journal of Immunology - November 18, 2009 Category: Allergy & Immunology Authors: Xiang J, McLinden JH, Rydze RA, Chang Q, Kaufman TM, Klinzman D, Stapleton JT Tags: J Immunol Source Type: journals
West Africa: Health Teams Launch Mass Yellow Fever Vaccinations
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The largest-ever mass vaccination campaign protecting populations from the dangerously infectious yellow fever disease will begin next week across three West African countries, the United Nations World Health Organization (WHO) announced today. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - November 17, 2009 Category: African Health Source Type: news
Yellow fever vaccination campaign to start
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17 November 2009 -- The largest-ever yellow fever mass vaccination campaign will kick off next week across three African countries. The week-long event will target 11.9 million people across Benin, Liberia and Sierra Leone, all three of which are at high risk of yellow fever outbreaks. (Source: WHO news)
Source: WHO news - November 17, 2009 Category: Global & Universal Source Type: organizations
Yellow fever vaccination drive to cover almost 12 million West Africans - UN
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The largest-ever mass vaccination campaign protecting populations from the dangerously infectious yellow fever disease will begin next week across three West African countries, the United Nations World Health Organization (WHO) announced today. (Source: UN News Centre - Health, Poverty, Food Security)
Source: UN News Centre - Health, Poverty, Food Security - November 17, 2009 Category: Global & Universal Source Type: organizations
Hepatitis A vaccine/yellow fever vaccine: Autoimmune hepatitis: case report
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(Source: Reactions)
Source: Reactions - November 16, 2009 Category: Drugs & Pharmacology Tags: Short communication Source Type: journals
Yellow fever vaccine: Acute disseminated encephalomyelitis: case report
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(Source: Reactions)
Source: Reactions - November 16, 2009 Category: Drugs & Pharmacology Tags: Short communication Source Type: journals
Clinical and immunological insights on severe adverse neurotropic/viscerotropic disease following 17D yellow fever vaccination.
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C, Teixeira-Carvalho A, Martins-Filho OA
Yellow fever vaccines (17D-204 and 17DD) are well tolerated, with a very low rate of severe adverse events (YEL-SAE), such as serious allergic reactions, neurotropic (YEL-AND) and viscerotropic (YEL-AVD) diseases. Viral and host factors have been postulated to explain the basis of YEL-SAE. However, the mechanisms underlying the occurrence of YEL-SAE still remain unknown. In the present investigation, a detailed immunological analysis of a 23-year-old female patient is presented. The patient developed a suspected case of severe YEL-AVD, with encephalitis as well as with pancreati...
Source: Clinical and Vaccine Immunology - November 11, 2009 Category: Allergy & Immunology Authors: Silva ML, Espírito-Santo LR, Martins MA, Silveira-Lemos D, Peruhype-Magalhães V, Caminha RC, de Andrade Maranhão-Filho P, Martins MA, de Menezes Martins R, Galler R, Freire MD, Marcovistz R, Homma A, Teuwen DE, Elói-Santos SM, Andrade Tags: Clin vaccine Immunol Source Type: journals
Direct random insertion of an influenza virus immunologic determinant into the NS1 glycoprotein of a vaccine flavivirus.
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A live chimeric vaccine virus against Japanese encephalitis (JE), ChimeriVax-JE, was used to define methods for optimal, random insertion of foreign immunologic determinants into flavivirus glycoproteins. The conserved M2e peptide of influenza A virus was randomly inserted into the yellow fever-specific NS1 glycoprotein of ChimeriVax-JE. A technique combining plaque purification with immunostaining yielded a recombinant virus that stably expressed M2e at NS1-236 site. The site was found permissive for other inserts. The insertion inhibited NS1 dimerization in vitro, which had no significant effect on virus replication ...
Source: Virology - November 11, 2009 Category: Virology Authors: Rumyantsev AA, Zhang ZX, Gao QS, Moretti N, Brown N, Kleanthous H, Delagrave S, Guirakhoo F, Collett MS, Pugachev KV Tags: Virology Source Type: journals
Membrane and envelope virus proteins co-expressed as lysosome associated membrane protein (LAMP) fused antigens: a potential tool to develop DNA vaccines against flaviviruses.
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Vaccination is the most practical and cost-effective strategy to prevent the majority of the flavivirus infection to which there is an available vaccine. However, vaccines based on attenuated virus can potentially promote collateral side effects and even rare fatal reactions. Given this scenario, the development of alternative vaccination strategies such as DNA-based vaccines encoding specific flavivirus sequences are being considered. Endogenous cytoplasmic antigens, characteristically plasmid DNA-vaccine encoded, are mainly presented to the immune system through Major Histocompatibility Complex class I - MHC I molecu...
Source: An Acad Bras Cienc - November 8, 2009 Category: Science Authors: Dhalia R, Maciel M, Cruz FS, Viana IF, Palma ML, August T, Marques ET Tags: An Acad Bras Cienc Source Type: journals
H1N1 vaccines too little, too late; most people already exposed and immune (opinion)
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(NaturalNews) The Big Pharma frenzy over H1N1 vaccines has turned into a circus of hilarious medical quackery thanks to the fact that by the time the vaccines are available, most people will have already been exposed to the virus. Hence, most people will have already built up their own H1N1 antibodies, rendering the vaccine not just useless, but downright laughable.Even with the outlandish rush to get these vaccines approved by the FDA -- a hurry that saw the complete abandonment of the principles of "scientific testing" -- Big Pharma just couldn't get these vaccines produced quickly enough to beat the virus itself. Taking...
Source: NaturalNews.com - November 6, 2009 Category: Consumer Health Advice Source Type: news
Administer Yellow Fever Vaccine With Caution
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ATLANTA — The yellow fever vaccine is contraindicated for individuals receiving immunosuppressive therapies and for those with immunosuppressant conditions, but it can be used with caution in pregnant and breastfeeding women and in HIV-infected individuals with mild immunosuppression and no symptoms. (Source: Ob.Gyn. News)
Source: Ob.Gyn. News - November 1, 2009 Category: OBGYN Authors: HEIDI SPLETE Tags: Obstetrics Source Type: journals
Exploring the molecular basis of insecticide resistance in the dengue vector Aedes aegypti: a case study in Martinique Island (French West Indies)
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Conclusion:
These results suggest that the high level of insecticide resistance found in Ae. aegypti mosquitoes from Martinique island is the consequence of both target-site and metabolic based resistance mechanisms. Insecticide resistance levels and associated mechanisms are discussed in relation with the environmental context of Martinique Island. These finding have important implications for dengue vector control in Martinique and emphasizes the need to develop new tools and strategies for maintaining an effective control of Aedes mosquito populations worldwide. (Source: BMC Genomics - Latest articles)
Source: BMC Genomics - Latest articles - October 26, 2009 Category: Genetics & Stem Cells Authors: Sebastien MarcombeRodolphe PoupardinFrederic DarrietStephane ReynaudJulien BonnetClare StrodeCecile BrenguesAndre YebakimaHilary RansonVincent CorbelJean-Philippe David Source Type: journals
[Vaccination and multiple sclerosis.]
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Vaccinations to prevent communicable diseases are, like in other chronic diseases, of special importance in patients with multiple sclerosis (MS). Various bacterial and viral infections have been shown to induce relapses of MS. Reports of possible adverse effects of vaccinations on the course of multiple sclerosis have led patients and treating physicians to exercise caution in the use of vaccines. A number of vaccines have been studied with respect to the risk in MS patients. Some vaccines, for example against yellow fever, are not indicated in MS due to the risk of MS exacerbation. In contrast, tetanus or hepatitis B...
Source: Der Nervenarzt - October 16, 2009 Category: Neurology Authors: Löbermann M, Winkelmann A, Reisinger EC, Zettl UK Tags: Nervenarzt Source Type: journals
Yellow fever vaccine and egg allergy: really a problem?
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(Source: Allergy)
Source: Allergy - October 11, 2009 Category: Allergy & Immunology Authors: R. Muñoz-Cano, J. Sanchez-Lopez, J. Bartra, A. Valero Source Type: journals
Preclinical and clinical development of YFV 17D-based chimeric vaccines against dengue, West Nile and Japanese encephalitis viruses.
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Dengue viruses (DENV), West Nile virus (WNV) and Japanese encephalitis virus (JEV) are major global health and growing medical problems. While a live-attenuated vaccine exists since decades against the prototype flavivirus, yellow fever virus (YFV), there is an urgent need for vaccines against dengue or West Nile diseases, and for improved vaccines against Japanese encephalitis. Live-attenuated chimeric viruses were constructed by replacing the genes coding for Premembrane (prM) and Envelope (E) proteins from YFV 17D vaccine strain with those of heterologous flaviviruses (ChimeriVax technology). This technology has bee...
Source: Vaccine - October 2, 2009 Category: Allergy & Immunology Authors: Guy B, Guirakhoo F, Barban V, Higgs S, Monath TP, Lang J Tags: vaccine Source Type: journals
Yellow fever in Cameroon
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On 8 September 2009, The Ministry of Health (MoH), Cameroon reported a laboratory-confirmed case of yellow fever, identified through routine yellow fever surveillance. The index case is from Kotto 1 - Bomboko village, Buea Health District, South-West Province. A reactive mass vaccination campaign is planned for October 2009 in two districts, Buea and Mbongue, with a target population of 165,138. (Source: WHO Disease Outbreaks)
Source: WHO Disease Outbreaks - October 1, 2009 Category: Infectious Diseases Source Type: organizations
Learning immunology from the yellow fever vaccine: innate immunity to systems vaccinology
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Nature Reviews Immunology 9, 741 (2009). doi:10.1038/nri2629
Author: Bali Pulendran
Despite their great success, we understand little about how effective vaccines stimulate protective immune responses. Two recent developments promise to yield such understanding: the appreciation of the crucial role of the innate immune system in sensing microorganisms and tuning immune responses, and advances in systems (Source: Nature Reviews Immunology)
Source: Nature Reviews Immunology - September 17, 2009 Category: Allergy & Immunology Authors: Bali Pulendran Tags: Perspectives Source Type: journals
Yellow Fever in a Brazilian Family Returning From Vacation in an Endemic Area: Relevant Clinical Features and Epidemiological Issues
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We report three cases of yellow fever (YF) in a family traveling from the city of Sao Paulo, Brazil (without previous vaccination) to an endemic area, acquiring the disease and presenting mild-to-moderate symptoms. Despite posing the intermittent risk of YF in endemic areas, it also alerts to the threat of introduction and spread of YF in the urban cycle, when infected travelers return to non-endemic areas where potential vectors are highly prevalent. (Source: Journal of Travel Medicine)
Source: Journal of Travel Medicine - September 9, 2009 Category: Infectious Diseases Authors: Tânia S. S. Chaves, Marileide J. Vasconcelos, Nosor Oliveira Filho, Jesse R Alves Source Type: journals
Yellow fever
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— Comprehensive overview covers symptoms, vaccine for this sometimes deadly mosquito-borne disease.
Sponsored by:Chemotherapy.com - http://www.chemotherapy.com (Source: MayoClinic.com Full Feed)
Source: MayoClinic.com Full Feed - August 27, 2009 Category: Consumer Health News Source Type: news
Monitoring adverse events following yellow fever vaccination using an integrated telephone and Internet-based system.
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TeleWatch is an automated telephone/Internet-based system that collects medical product adverse event reports in real-time through an algorithm driven by the patient. 1341 patients, who received yellow fever vaccine and were recruited through 15 travel clinics, contacted the system within 48h of vaccination and 765 (57%) made follow-up contacts. Participation rates were higher among females and persons older than 60 years of age. TeleWatch can be expanded for use in large campaigns involving influenza or other vaccines.
PMID: 19712766 [PubMed - as supplied by publisher] (Source: Vaccine)
Source: Vaccine - August 23, 2009 Category: Allergy & Immunology Authors: Durbin AP, Setse R, Omer SB, Palmer JG, Spaeder JA, Baker J, Lessans F, Halsey NA Tags: vaccine Source Type: journals
Vaccination as a Triggering Event for Autoimmune Hepatitis
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Semin Liver Dis 2009; 29: 331-334DOI: 10.1055/s-0029-1233537ABSTRACTThe pathogenesis of autoimmune hepatitis entails complex interactions between triggering factors, autoantigens, genetic predisposition, and immunoregulatory networks. Implicated triggering factors are numerous and include toxins, medications, and infectious agents. In this article, we present a unique case of a 31-year-old woman with severe autoimmune hepatitis apparently abruptly triggered by vaccination. All evidence suggests this was an idiosyncratic response to either hepatitis A or yellow fever vaccination.[...]© Thieme Medical PublishersGet connecte...
Source: Seminars in Liver Disease - August 13, 2009 Category: Gastroenterology Tags: DIAGNOSTIC PROBLEMS IN HEPATOLOGY Source Type: journals
Viscerotropic disease following yellow fever vaccination in Peru.
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Five suspected cases of yellow fever vaccine-associated viscerotropic disease (YEL-AVD) clustered in space and time following a vaccination campaign in Ica, Peru in 2007. All five people received the same lot of 17DD live attenuated yellow fever vaccine before their illness; four of the five died of confirmed YEL-AVD. The surviving case was classified as probable YEL-AVD. Intensive investigation yielded no abnormalities of the implicated vaccine lot and no common risk factors. This is the first described space-time cluster of yellow fever viscerotropic disease involving more than two cases. Mass yellow fever vaccinatio...
Source: Vaccine - August 9, 2009 Category: Allergy & Immunology Authors: Whittembury A, Ramirez G, Hernández H, Ropero AM, Waterman S, Ticona M, Brinton M, Uchuya J, Gershman M, Toledo W, Staples E, Campos C, Martínez M, Chang GJ, Cabezas C, Lanciotti R, Zaki S, Montgomery JM, Monath T, Hayes E Tags: vaccine Source Type: journals
TLR expression and NK cell activation after human yellow fever vaccination.
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The yellow fever vaccine is very effective with a single injection conferring protection for atleast 10 years. Recent evidence suggests that the innate immune cells activated through Toll-like receptors (TLRs), are critical determinants of the robustness of the adaptive response. Therefore, we investigated the NK cell status in eight healthy volunteers after vaccination with YF 17DD virus. Shortly after vaccination, we observed increased expression of TLR-3 and TLR-9 in NK cells and markers such as CD69, HLA-DP-DQ-DR, CD38 and CD16. The up-regulation of CD69 was positively correlated with the presence of TLRs throughou...
Source: Vaccine - July 28, 2009 Category: Allergy & Immunology Authors: Neves PC, Matos DC, Marcovistz R, Galler R Tags: vaccine Source Type: journals
Abu Dhabi group launches vaccine service
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The Abu Dhabi Health Services Company's Ambulatory Healthcare Services has announced the launch of its Travel Medicine service which offers some of the most commonly used vaccines such as Meningococcal, Yellow Fever, Typhoid, Malaria Prophylaxis, Rabies and Hepatitis A to travellers. The centres will be open Sunday through to Thursday. (Source: Healthcare)
Source: Healthcare - June 1, 2009 Category: Middle East Health Source Type: info
The Brazilian vaccine manufacturers' perspective and its current status.
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This article aims to give an overview of the current situation and perspectives for the Brazilian vaccine manufacturers, who play strong roles for developing countries in this field. The research, development and production of immunobiologicals in Brazil, especially vaccines for human use, is mainly supported by governmental institutions linked to the Ministry of Health as part of a strategy that prioritizes the public sector for access to vaccines and other biologicals that are regarded essential for the population. As a result, 83% of the vaccines required in 2007 were provided by national vaccine producers and only 17% ...
Source: Biologicals : Journal of the International Association of Biological Standardization - June 1, 2009 Category: Biotechnology Authors: Homma A Tags: Biologicals Source Type: journals
Yellow fever vaccine - how does it work and why do rare cases of serious adverse events take place?
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Yellow fever 17D vaccine is one of the most successful vaccines ever developed and over 540 million doses have been used. Nevertheless there has been very little known about the mechanism of protection induced by the vaccine. The last couple of years have seen important advances made in understanding how the vaccine works involving studies of the innate and adaptive immune responses plus a systems biology approach. Like all vaccines, the 17D vaccine causes rare serious adverse events (SAEs) following immunization. At present, the mechanism(s) of SAEs is(are) poorly understood but our advances in understanding the immun...
Source: Current Opinion in Immunology - May 31, 2009 Category: Allergy & Immunology Authors: Barrett AD, Teuwen DE Tags: Curr Opin Immunol Source Type: journals
International Health Organizations Urge More Funding For Yellow Fever Vaccine Stockpile
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The International Coordinating Group (ICG) on Yellow Fever Vaccine Provision is warning that the global emergency stockpile of yellow fever vaccine for the world's most vulnerable populations in Africa is under threat. The current stockpile is scheduled to run out in 2010 and there is no funding to cover campaigns once the stockpile is depleted. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - May 28, 2009 Category: Consumer Health News Tags: Immune System / vaccines Source Type: news
More funding urged for yellow fever vaccine stockpile
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26 May 2009 -- The International Coordinating Group (ICG) on Yellow Fever Vaccine Provision is warning that the global emergency stockpile of yellow fever vaccine for the world’s most vulnerable populations in Africa is under threat. (Source: WHO news)
Source: WHO news - May 26, 2009 Category: Global & Universal Source Type: organizations
Antirheumatics/immunosuppressants/yellow fever vaccine: Various toxicities: 16 case reports
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(Source: Reactions)
Source: Reactions - May 10, 2009 Category: Drugs & Pharmacology Tags: Short communication Source Type: journals
Antirheumatics/immunosuppressants/yellow fever vaccine: Various toxicities: 16 case reports.
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Page: 8 (Source: Reactions Weekly)
Source: Reactions Weekly - May 10, 2009 Category: Drugs & Pharmacology Tags: HTML Source Type: journals
Successful Immunization of an Allogeneic Bone Marrow Transplant Recipient with Live, Attenuated Yellow Fever Vaccine
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We report the successful and uneventful immunization of a 62-year-old man with a history of allogeneic bone marrow transplant and discuss evidence for this recommendation. (Source: Journal of Travel Medicine)
Source: Journal of Travel Medicine - May 4, 2009 Category: Infectious Diseases Authors: Justin A. Yax, Eileen C. Farnon, N. Cary Engleberg Source Type: journals
Highly specific detection of antibodies to tick-borne encephalitis (TBE) virus in humans using a domain III antigen and a sensitive immune complex (IC) ELISA
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Conclusion: Obviously, the IC ELISA is able to detect human antibodies to small antigens with only few serotype-specific epitopes with high specificity and sensitivity. (Source: Journal of Clinical Virology)
Source: Journal of Clinical Virology - May 1, 2009 Category: Virology Authors: Diana Ludolfs, Michael Reinholz, Herbert Schmitz Tags: Full length articles Source Type: journals
Existing antiviral vaccines
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This article will review vaccination for the following viral diseases: measles, mumps, rubella, polio, hepatitis A, hepatitis B, influenza, rotavirus, rabies, monkeypox, smallpox, Japanese encephalitis, and yellow fever. (Source: Dermatologic Therapy)
Source: Dermatologic Therapy - March 25, 2009 Category: Dermatology Authors: Parisa Ravanfar, Anita Satyaprakash, Rosella Creed, Natalia Mendoza Tags: vaccines in Dermatology Source Type: journals
Yellow Fever Vaccine Safe and Immunogenic for HIV-Infected Patients
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Live, attenuated yellow fever vaccine (17DV) appears to be safe and immunogenic in patients infected with HIV, Swiss and German researchers report. Reuters Health Information (Source: Medscape Allergy Headlines)
Source: Medscape Allergy Headlines - March 23, 2009 Category: Allergy & Immunology Tags: Infectious Diseases Source Type: info
Development of a human-murine chimeric immunoglobulin M for use in the serological detection of human flavivirus antibodies.
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Current diagnosis of human flaviviral infections relies heavily on serological techniques such as the immunoglobulin (Ig) M antibody capture enzyme-linked immunosorbent assay (MAC-ELISA). Broad application of this assay is hindered by the lack of standardized positive human control sera that react with the wide variety of flaviviruses that can cause human disease, e.g., dengue (DEN), West Nile (WN), yellow fever (YF), Japanese encephalitis (JE), and Saint Louis encephalitis virus (SLEV). We have created a human-murine chimeric antibody combining the variable regions of a broadly flavivirus cross-reactive murine monoclo...
Source: Clinical and Vaccine Immunology - March 18, 2009 Category: Allergy & Immunology Authors: Thibodeaux BA, Roehrig JT Tags: Clin vaccine Immunol Source Type: journals
A note of caution on yellow fever vaccination during maraviroc treatment: a hypothesis on a potential dangerous interaction.
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Page: 542DOI: 10.1097/QAD.0b013e328323aeb4Authors: Roukens, Anna H; Visser, Leo G; Kroon, Frank P (Source: AIDS)
Source: AIDS - February 26, 2009 Category: Infectious Diseases Tags: HTML PDF (826 K) Source Type: journals
Cluster-sample surveys and lot quality assurance sampling to evaluate yellow fever immunisation coverage following a national campaign, Bolivia, 2007
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Conclusions Estimated YF coverage was high. Discrepancies between administrative coverage and LQAS results may be due to incorrect population data. Even allowing for clustering in LQAS, the statistical errors would remain low. Catch-up campaigns are recommended in districts with unacceptable coverage. (Source: Tropical Medicine and International Health)
Source: Tropical Medicine and International Health - January 28, 2009 Category: Tropical Medicine Authors: Lorenzo Pezzoli, Silvia Pineda, Percy Halkyer, Gladys Crespo, Nick Andrews, Olivier Ronveaux Source Type: journals
Guinea: UN Health Agency Backs Mass Yellow Fever Vaccination Campaign
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A large-scale yellow fever vaccination campaign has been slated for later this month in Guinea after the United Nations World Health Organization (WHO) confirmed two men had contracted the deadly disease in the West African nation. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - January 14, 2009 Category: African Health Source Type: news
Vaccines: Predicting immunity
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Nature Reviews Immunology 9, 4 (2009). doi:10.1038/nri2478
Author: Olive Leavy
Two recent studies have used systems biology approaches to identify early gene 'signatures' induced in humans vaccinated with the attenuated yellow fever vaccine YF17D that correlate with, and in some cases predict, the subsequent adaptive immune response.YF17D, which is one of the most effective (Source: Nature Reviews Immunology)
Source: Nature Reviews Immunology - December 24, 2008 Category: Allergy & Immunology Authors: Olive Leavy Tags: Research Highlight Source Type: journals
International Travel Health Alert: Yellow Fever Vaccine Shortage 2009
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All travelers who have recommendations or requirements for yellow fever vaccines on their travel itineraries need to contact licensed yellow fever travel clinics as soon as possible if they are traveling prior to July 2009. (Source: dukehealth.org: Duke Health News)
Source: dukehealth.org: Duke Health News - December 22, 2008 Category: Consumer Health News Tags: Infectious Diseases Travel Clinic Source Type: news
Yellow fever vaccine induces integrated multilineage and polyfunctional immune responses
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In this study, we have used functional genomics and polychromatic flow cytometry to define the signature of the immune response to the yellow fever (YF) vaccine 17D (YF17D) in a cohort of 40 volunteers followed for up to 1 yr after vaccination. We show that immunization with YF17D leads to an integrated immune response that includes several effector arms of innate immunity, including complement, the inflammasome, and interferons, as well as adaptive immunity as shown by an early T cell response followed by a brisk and variable B cell response. Development of these responses is preceded, as demonstrated in three independent...
Source: The Journal of Experimental Medicine - December 22, 2008 Category: Internal Medicine Authors: Gaucher, D., Therrien, R., Kettaf, N., Angermann, B. R., Boucher, G., Filali-Mouhim, A., Moser, J. M., Mehta, R. S., Drake, D. R., Castro, E., Akondy, R., Rinfret, A., Yassine-Diab, B., Said, E. A., Chouikh, Y., Cameron, M. J., Clum, R., Kelvin, D., Somog Tags: Articles Source Type: journals
Systems biology approach predicts immunogenicity of the yellow fever vaccine in humans
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an Aderem, Rafi Ahmed
& Bali Pulendran (Source: Nature Immunology)
Source: Nature Immunology - November 23, 2008 Category: Allergy & Immunology Authors: Troy D QuerecRama S AkondyEva K LeeWeiping CaoHelder I NakayaDirk TeuwenAli PiraniKim GernertJiusheng DengBruz MarzolfKathleen KennedyHaiyan WuSoumaya BennounaHerold OluochJoseph MillerRicardo Z VencioMark MulliganAlan AderemRafi AhmedBali Pulendran Tags: Resources Source Type: journals
Does yellow fever 17D vaccine protect against melanoma?
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BCG vaccine, vaccinia vaccine and certain pathogens that were shown in previous studies to protect against melanoma have antigenic determinants homologous in their amino acids sequence with the melanoma antigen HERV-K-MEL, encoded by a human endogenous retrovirus K (HERV-K), which is expressed in about 95% of malignant melanocytes. Yellow fever vaccine (YFV) likewise contains an antigenic determinant with a close homology to HERV-K-MEL and might therefore also confer protection against melanoma. To investigate this possibility we carried out a cohort study (28,306 subjects) and a nested case-control study (37 melamona ...
Source: Vaccine - November 13, 2008 Category: Allergy & Immunology Authors: Mastrangelo G, Krone B, Fadda E, Buja A, Grange JM, Rausa G, Koelmel KF Tags: vaccine Source Type: journals
Detection of West Nile Virus-Neutralizing Antibodies in Avian and Equine Serum Using a Surrogate Chimeric Virus.
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A chimeric yellow fever/West Nile virus was compared to West Nile virus (WNV) alone as a biosafety-level-2 reagent in the plaque reduction neutralization test for determining WNV infection histories. Concordance was 96.3% among 188 avian and equine serum samples. Neutralizing antibody titers were frequently >2-fold lower using the chimera.
PMID: 19005021 [PubMed - as supplied by publisher] (Source: Clinical and Vaccine Immunology)
Source: Clinical and Vaccine Immunology - November 12, 2008 Category: Allergy & Immunology Authors: Komar N, Langevin S, Monath TP Tags: Clin vaccine Immunol Source Type: journals
Burkina Faso: Yellow Fever Cases Spark Fresh Vaccine Campaign
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Two boys in northern Burkina Faso have contracted yellow fever in a fresh outbreak of the disease that has already claimed the life of the eldest child, the United Nations World Health Organization (WHO) reported today. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - November 4, 2008 Category: African Health Source Type: news
Yellow fever vaccine: past, present and future
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Expert Opinion on Biological Therapy , November 2008, Vol. 8, No. 11, Pages 1787-1795.
Background: Yellow fever is a re-emerging infectious disease, as vector control and routine immunisation have dwindled in endemic areas in the last few decades. There is a constant threat of outbreaks in the large susceptible non-immune population of the ... (Source: Expert Opinion: Expert Opinion on Biological Therapy: Table of Contents)
Source: Expert Opinion: Expert Opinion on Biological Therapy: Table of Contents - October 10, 2008 Category: Drugs & Pharmacology Tags: article Source Type: journals
Analysis of Yellow Fever Vaccination Practice in England
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Conclusions. The NaTHNaC program of registration, training, standards, and audit should help to meet important needs in practice settings and contribute to an improvement in travel health. (Source: Journal of Travel Medicine)
Source: Journal of Travel Medicine - October 2, 2008 Category: Infectious Diseases Authors: Naomi Bryant, Rosemary Tucker, Hilary Simons, Stella Bailey, John Mathewson, Gil Lea, David R. Hill Tags: ORIGINAL ARTICLES Source Type: journals
