Cervical Cancer
This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader, such as GoogleReader, or to display this data on your own website or blog. 
Subscribe to this data using MyMedWorm.
Subscribe to this data using GoogleReader.
Subscribe to this data using Bloglines.
Subscribe to this data using MyYahoo.
Get the very latest Swine Flu news via the MedWorm Swine Flu RSS news feed - updated hourly from thousands of authoritative health and news sources.
This page shows you your search results in order of date.
7381 records returned
New cervical cancer screening guidelines released
Email this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
The new mammogram recommendations out earlier this week caused quite an uproar. Now comes another change in screening tests for women -- this one for cervical cancer. (Source: CNN.com - Health)
Source: CNN.com - Health - November 20, 2009 Category: Consumer Health News Source Type: news
First Mammograms, Now Changes For Pap SmearsEmail this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
Most women in their 20s can have a Pap smear every two years instead of annually, say new guidelines that conclude that's enough to catch slow-growing cervical cancer. (Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire)
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - November 20, 2009 Category: Consumer Health News Source Type: consumer
New guidelines push back age for Pap smearsEmail this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
CHICAGO (Reuters) - Women in the United States should start cervical cancer screening at age 21 and most do not need an annual Pap smear, according to new guidelines issued on Friday that aim to reduce the risk of unnecessary treatment. (Source: Reuters: Health)
Source: Reuters: Health - November 20, 2009 Category: Consumer Health News Tags: healthNews Source Type: news
U.S. guidelines call for fewer Pap tests for womenEmail this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
The American College of Obstetricians and Gynecologists are recommending fewer Pap smears for most women in their 20s. They say tests every two years is enough to catch slow-growing cervical cancer in women under 30. (Source: CTV Health)
Source: CTV Health - November 20, 2009 Category: Consumer Health News Source Type: news
Report: You Don't Need Pap Smears Every YearEmail this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
Most women in their 20s can have a Pap smear every two years instead of annually, say new guidelines that conclude that's enough to catch slow-growing cervical cancer. (Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire)
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - November 20, 2009 Category: Consumer Health News Source Type: consumer
Change Ahead for Cervical Cancer DetectionEmail this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
Women in their 20s Should Get Pap Smear Every Two Years, Not Annually, OB/GYN Organization Says (Source: Health News: CBSNews.com)
Source: Health News: CBSNews.com - November 20, 2009 Category: Consumer Health News Source Type: news
New Guidelines Suggest Less Frequent Pap SmearsEmail this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
Most women in their 20s can have a Pap smear every two years instead of annually, say new guidelines that conclude that's enough to catch slow-growing cervical cancer. (Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire)
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - November 20, 2009 Category: Consumer Health News Source Type: consumer
Group recommends less-frequent Pap testsEmail this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
The cervical cancer screening advice follows another panel's controversial mammogram report, but experts say it's a much different situation. Still, Paps are the only reason some women see a doctor.
Only days after a federal panel scaled back on breast cancer screening recommendations for many women, another organization -- the American College of Obstetricians and Gynecologists -- has done the same for a screening credited with drastically reducing the rates of cervical cancer in the U.S. (Source: Los Angeles Times - Science)
Source: Los Angeles Times - Science - November 20, 2009 Category: Science Source Type: news
Aspirin kills 400% more people than H1N1 swine fluEmail this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
(NaturalNews) The CDC now reports that nearly 4,000 Americans have been killed by H1N1 swine flu. This number is supposed to sound big and scary, motivating millions of people to go out and pay good money to be injected with untested, unproven H1N1 vaccines. But let's put the number in perspective: Did you know that more than four times as many people are killed each year by common NSAID painkillers like aspirin?The July 1998 issue of The American Journal of Medicine explains it as follows:"Conservative calculations estimate that approximately 107,000 patients are hospitalized annually for nonsteroidal anti-inflammatory dr...
Source: NaturalNews.com - November 20, 2009 Category: Consumer Health Advice Source Type: news
Guidelines Push Back Age for Cervical Cancer TestsEmail this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
New guidelines for cervical cancer screening say women should delay their first Pap test until age 21, and go for screening less often than had been previously recommended. (Source: NYT > Health)
Source: NYT > Health - November 20, 2009 Category: Consumer Health News Authors: By DENISE GRADY Tags: Tests and Testing Human Papilloma Virus (HPV) cervix cancer American College of Obstetricians and Gynecologists Source Type: news
News Analysis: Culture Clash in MedicineEmail this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
New recommendations on breast and cervical cancer screening have been met with anger and confusion, not to mention a measure of political posturing. (Source: NYT > Health)
Source: NYT > Health - November 20, 2009 Category: Consumer Health News Authors: By KEVIN SACK Tags: Mammography Tests and Testing Medicine and Health Health Insurance and Managed Care American College of Obstetricians and Gynecologists Source Type: news
New guidelines: Pap smears should start at age 21Email this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
CHICAGO (Reuters) - Women in the United States should start cervical cancer screening at age 21 and most do not need an annual Pap smear, according to new guidelines issued on Friday that aim to reduce the risk of unnecessary treatment. (Source: Reuters: Health)
Source: Reuters: Health - November 20, 2009 Category: Consumer Health News Tags: healthNews Source Type: news
New guidelines: Pap tests should start at age 21Email this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
Young women should have their first Pap test no sooner than age 21, regardless of when they become sexually active, say new guidelines from the American College of Obstetricians and Gynecologists. Earlier screening for cervical cancer may lead to unnecessary and possibly harmful treatments for an increasingly rare cancer, according to ACOG, the leading U.S. professional organization for obstetricians and gynecologists. (Source: CNN.com - Health)
Source: CNN.com - Health - November 20, 2009 Category: Consumer Health News Source Type: news
Women can wait until age 21 for cervical cancer test, group saysEmail this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
Women can delay having their first Pap test for cervical cancer until they turn 21 and many can wait longer to go back for follow-up screenings, according to new guidelines released Friday by a major medical group. (Source: Wash Post Health)
Source: Wash Post Health - November 20, 2009 Category: Consumer Health News Authors: Rob Stein Tags: Women can wait until age 21 for cervical cancer test, group says Source Type: news
cDNA Microarray Analysis of Serially Sampled Cervical Cancer Specimens From Patients Treated With ThermochemoradiotherapyEmail this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
Conclusions: Microarrays showed minor changes in gene expression after thermochemoradiotherapy in locally advanced cervical cancer. We detected 53 differentially expressed genes, mainly involved in fibrosis, tumorigenesis, and immune response. A limitation with the use of serial biopsy specimens was low quality of ribonucleic acid from tumors that respond to highly effective therapy. Another “key limitation” is timing of the post-treatment biopsy, because 24 h may be too late to adequately assess the impact of hyperthermia on gene expression. (Source: International Journal of Radiation Oncology * Biology * Physics)
Source: International Journal of Radiation Oncology * Biology * Physics - November 19, 2009 Category: Radiology Authors: Erling Dahl Borkamo, Baard-Christian Schem, Øystein Fluge, Ove Bruland, Olav Dahl, Olav Mella Tags: Biology Contributions Source Type: journals
CDC Lifts HPV Vaccination Requirement For Young Female ImmigrantsEmail this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
Starting Dec. 14, the U.S. will no longer require female immigrants seeking permanent resident status to be vaccinated against the human papillomavirus, the Centers for Disease Control and Prevention announced on Friday, the AP/San Francisco Chronicle reports. The new rule revises July 2008 guidelines that required female immigrants ages 11 through 26 seeking legal U.S. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 19, 2009 Category: Consumer Health News Tags: cervical cancer / HPV Vaccine Source Type: news
Nigeria: LASG Appeals to Women On Cervical CancerEmail this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
A spokesperson of Lagos state government (LASG) the Commissioner for Health, Dr Jide Idris has urged women to take advantage of the state government periodic free cervical cancer screening programme to examine themselves just has he noted that no fewer than 1006 women benefited from the latest exercise in the Ikorodu Division of the state. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - November 19, 2009 Category: African Health Source Type: news
Role of TGF-beta1 (-509C>T) promoter polymorphism in susceptibility to cervical cancer.Email this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
In conclusion, our data suggest that TGF-beta1 -509T allele confers marginal protection for early stage 1B but risk for stage II of cervical cancer.
PMID: 19911703 [PubMed - in process] (Source: Oncology Research)
Source: Oncology Research - November 18, 2009 Category: Cancer & Oncology Authors: Singh H, Jain M, Mittal B Tags: Oncol Res Source Type: journals
Odontoid metastasis: a potential lethal complicationEmail this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
We describe a 40-year-old woman with a history of breast cancer who presented
with neck and shoulder pain of 1 week duration with no neurological deficit. Following clinical examination, radiographs taken
of the cervical spine was normal. Radiographs repeated 3 weeks later revealed a large lytic lesion of the odontoid occupying
70–80% of the peg. Further investigation including magnetic resonance imaging and bone scan showed no further spinal lesions.
She underwent cyclical radiotherapy with complete resolution of the odontoid peg lesion and clinically was asymptomatic at
2 years. Metastatic lesions o...
Source: Journal of Orthopaedics and Traumatology - November 18, 2009 Category: Orthopaedics Tags: Journal of Orthopaedics and Traumatology Source Type: journals
Impact of lymph-node metastasis site in patients with thoracic esophageal cancerEmail this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
We retrospectively compared surgical outcomes between patients with intra-thoracic and extra-thoracic (cervical and abdominal) lymph-node metastasis.The study population comprised 96 patients with lymph-node metastasis who had undergone curative esophagectomy for thoracic esophageal cancer. The patients were grouped according to whether the site of lymph-node metastasis was intra-thoracic, extra-thoracic, or both intra-thoracic and extra-thoracic. The patient characteristics, survival time, and prognostic factors were compared.The most significant difference in disease-specific survival was detected at a threshold value of...
Source: Journal of Surgical Oncology - November 18, 2009 Category: Cancer & Oncology Authors: Chikara Kunisaki, Hirochika Makino, Jun Kimura, Takashi Oshima, Shoichi Fujii, Ryo Takagawa, Takashi Kosaka, Hidetaka A. Ono, Hirotoshi Akiyama Source Type: journals
Labeling of cervical lymph node levels during neck dissection: From ex vivo to in situ mappingEmail this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
To analyze the error rate of ex vivo mapping and to evaluate in situ mapping of lymph node (LN) levels during neck dissection (ND)We retrospectively reviewed the pathological data on metastatic LN levels in head and neck cancer patients that had ND and ex vivo mapping of LN levels. Among them, we included the data from 43 patients that had a high risk for metastatic nodes based on both the preoperative CT and PET/CT. We compared the metastatic node levels based on the radiological studies and surgical pathology. In addition, we prospectively evaluated the accuracy of in situ mapping (N = 20).With ex vivo mapping, the discr...
Source: Journal of Surgical Oncology - November 18, 2009 Category: Cancer & Oncology Authors: Seung Hoon Woo, Yoon Kyoung So, Jong-In Jeong, Hayoung Byun, Won-Yong Lee, Han-Sin Jeong Source Type: journals
Cancer biology: Gene highs and lowsEmail this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
Nature 462, 254 (2009). doi:10.1038/462254c
PLoS Genet.5, e1000719 (2009) 10.1371/journal.pgen.1000719A large-scale survey of gene loss or gain in cervical cancer has flagged more than 50 potential genetic drivers of the disease.Heidi Lyng and her colleagues at the Norwegian Radium Hospital in Oslo screened (Source: Nature)
Source: Nature - November 18, 2009 Category: Research Tags: Research Highlights Source Type: journals
Soluble B and T Lymphocyte Attenuator Possesses Antitumor Effects and Facilitates Heat Shock Protein 70 Vaccine-Triggered Antitumor Immunity against a Murine TC-1 Cervical Cancer Model In Vivo.Email this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
B and T lymphocyte attenuator (BTLA)-herpesvirus entry mediator (HVEM) signaling coinhibitory pathway is believed to impair antitumor immune competences. An intriguing unresolved question is whether blockade of BTLA-HVEM guides an effective therapeutic tool against established tumors. To address this issue, we constructed a eukaryotic expression plasmid (psBTLA) that expressed the extracellular domain of murine BTLA (soluble form of BTLA), which could bind HVEM, the ligand of BTLA, and block BTLA-HVEM interactions. The data in this study showed that treatment by injection of psBTLA resulted in down-regulation of IL-10 ...
Source: Journal of Immunology - November 18, 2009 Category: Allergy & Immunology Authors: Han L, Wang W, Fang Y, Feng Z, Liao S, Li W, Li Y, Li C, Maitituoheti M, Dong H, Lai Z, Gao Q, Xi L, Wu M, Wang D, Zhou J, Meng L, Wang S, Ma D Tags: J Immunol Source Type: journals
Prevention and treatment of cervical cancer in mice using estrogen receptor antagonists [Medical_Sciences]Email this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
The majority of human cervical cancers are associated with the high-risk human papillomavirus (HPV) types. In mouse models for HPV-associated... (Source: Proceedings of the National Academy of Sciences)
Source: Proceedings of the National Academy of Sciences - November 17, 2009 Category: Science Authors: Chung, S.-H., Lambert, P. F. Tags: Medical_Sciences Source Type: journals
Botswana: Pap Smear Key to Battle Against Cervical CancerEmail this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
A papanicolaou cervical smear test, or Pap smear as it is commonly known, is a test of a sample of cells taken from a woman's cervix. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - November 17, 2009 Category: African Health Source Type: news
Predicting Residual Neck Disease in Patients With Oropharyngeal Squamous Cell Carcinoma Treated With Radiation Therapy: Utility of p16 Status [Original Article]Email this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
Conclusions In conjunction with other clinical parameters, p16 status can help predict the need for post-RT ND in patients with OP-SCCA. Although close observation may be warranted in selected patients with p16+ tumors, patients with p16– tumors are at much higher risk for residual neck disease, even when initial nodal disease is less advanced. (Source: Archives of Otolaryngology)
Source: Archives of Otolaryngology - November 16, 2009 Category: ENT & OMF Authors: Shonka, D. C., Shoushtari, A. N., Thomas, C. Y., Moskaluk, C., Read, P. W., Reibel, J. F., Levine, P. A., Jameson, M. J. Tags: Oncology, Head & Neck cancer, Otolaryngology/ Head & Neck Surgery, Neoplasms of Head & Neck, Radiation Therapy, Papillomavirus, Human, Prognosis/ Outcomes Original Article Source Type: journals
Factors That Determine Satisfaction With Surgical Treatment of Low-Income Women With Breast Cancer [Original Article]Email this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
Conclusion Our findings highlight the importance of 2 relatively simple behaviors that surgeons can easily implement to increase patient satisfaction, which can be of potential benefit in the litigious world of today. (Source: Archives of Surgery)
Source: Archives of Surgery - November 16, 2009 Category: Surgery Authors: Thind, A., Diamant, A., Liu, Y., Maly, R. Tags: Medical Practice, Medical Practice, Other, Oncology, Breast cancer, Patient-Physician Relationship/ Care, Patient-Physician Communication, Patient Education/ Health Literacy, Patient-Physician Relationship, Other, Quality of Care, Quality of Care, Other, Source Type: journals
FDA approves cervical cancer vaccineEmail this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
Cervarix has won FDA approval for the prevention of cervical pre-cancers and cervical cancer associated with HPV-16 and HPV-18 for use in girls and young women (ages 10-25), according to GlaxoSmithKline. In clinical trials, the vaccine was shown to be 93% effective in the prevention of cervical pre-cancers associated with HPV -16 or 18, in women without evidence of current infection with, or prior exposure to, the same HPV type at the time of vaccination. (Source: Cancer Network)
Source: Cancer Network - November 16, 2009 Category: Cancer & Oncology Source Type: info
Cervical cancer effectively treated with ER-alpha blockersEmail this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
Cervical cancer could one day be effectively treated with fulvestrant and raloxifene, two drugs currently used to treat breast cancer and osteoporosis, show results of an animal study. (Source: MedWire News - Ob/Gyn)
Source: MedWire News - Ob/Gyn - November 16, 2009 Category: OBGYN Source Type: news
Genetic changes associated with disease progression in cervical cancerEmail this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
Study findings suggest that specific genetic changes are responsible for the progression of cervical cancer toward an aggressive and treatment-resistant state. (Source: MedWire News - Ob/Gyn)
Source: MedWire News - Ob/Gyn - November 16, 2009 Category: OBGYN Source Type: news
Genetic Changes Shown To Be Important Indicators For Disease Progression In Cervical Cancer PatientsEmail this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
Cervical cancer patients with specific changes in the cancer genome have a three- or fourfold increased risk of relapse after standard treatment compared to patients without these changes, according to a new study. The research suggests that specific genetic changes are crucial steps in the progression of the disease towards an aggressive and treatment-resistant state. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - November 15, 2009 Category: Science Source Type: news
Risk of gynecological cancers in users of estradiol/dydrogesterone or other HRT preparations.Email this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
CONCLUSION: This study provides evidence that the risk of developing gynecological cancers with E/D use of several months to a few years is similar to the risks of developing gynecological cancer without HRT or use of other HRT.
PMID: 19905903 [PubMed - in process] (Source: Climacteric)
Source: Climacteric - November 15, 2009 Category: Geriatrics Authors: Schneider C, Jick SS, Meier CR Tags: Climacteric Source Type: journals
Centers For Medicare & Medicaid Services Approves FDG PET For Cervical Cancer StagingEmail this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
SNM applauds the Centers for Medicare & Medicaid Services' (CMS) decision to expand coverage of FDG PET for the initial staging of cervical cancer without previously imposed restrictions. "CMS' decision to expand coverage of FDG PET for the initial treatment strategy evaluation of cervical cancer is important for patient care," said Michael M. Graham, Ph.D., M.D., president of SNM. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 14, 2009 Category: Consumer Health News Tags: cervical cancer / HPV Vaccine Source Type: news
Centers For Medicare & Medicaid Services Approves FDG PET For Cervical Cancer StagingEmail this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
SNM applauds the Centers for Medicare & Medicaid Services' (CMS) decision to expand coverage of FDG PET for the initial staging of cervical cancer without previously imposed restrictions. "CMS' decision to expand coverage of FDG PET for the initial treatment strategy evaluation of cervical cancer is important for patient care," said Michael M. Graham, Ph.D., M.D., president of SNM. (Source: MRI / PET / Ultrasound News From Medical News Today)
Source: MRI / PET / Ultrasound News From Medical News Today - November 14, 2009 Category: Radiology Tags: cervical cancer / HPV Vaccine Source Type: news
Guided Therapeutics Non-Invasive Cervical Cancer Detection Device Trial Confirms Current Tests Miss DiseaseEmail this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
Results of the FDA pivotal clinical trial for the LightTouch" Non-invasive Cervical Cancer Detection Device conducted by Guided Therapeutics, Inc. (GT), indicated that the current system for diagnosing cervical disease missed the same amount of disease as a landmark study carried out by the National Cancer Institute (NCI). (Source: Cancercompass News: Gynecological Cancer)
Source: Cancercompass News: Gynecological Cancer - November 14, 2009 Category: Cancer & Oncology Source Type: news
Macrophage migration inhibitory factor expression in cervical cancerEmail this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
Conclusions MIF has been shown to promote tumor immune escape mechanisms in other cancer entities, which makes it an interesting target
for cancer therapy, given the known significance of immune mechanisms for uterine cervical cancer. The overexpression of MIF
on the protein and mRNA level, as well as its secretion by cervical cancer cells points to a critical role of the protein
for the pathogenesis of uterine cervical cancer.
Content Type Journal ArticleCategory Original PaperDOI 10.1007/s00432-009-0702-5Authors
Mathias Krockenberger, University of Wuerzburg Department of Obstetrics and Gynecology ...
Source: Journal of Cancer Research and Clinical Oncology - November 13, 2009 Category: Cancer & Oncology Tags: Journal of cancer Research and Clinical Oncology Source Type: journals
Cervical cancer vaccine hope for African womenEmail this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
DAR ES SALAAM (Reuters) - So crammed is Tanzania's only cancer treatment center that Rukia Kondogoza, wrapped in bright kanga cloth, has to share her bed with another patient. (Source: Reuters: Health)
Source: Reuters: Health - November 13, 2009 Category: Consumer Health News Tags: healthNews Source Type: news
CMS Removes Data Collection Restrictions on PET to Stage Cervical CancerEmail this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
In a final coverage decision released Nov. 10, CMS says it has ended prospective data collection requirements for positron emission tomography used in the initial staging of cervical cancer. The agency... (Source: OncologySTAT Latest News)
Source: OncologySTAT Latest News - November 13, 2009 Category: Cancer & Oncology Source Type: news
Disease Progression And Survival Of Cervical Cancer Patients: Genetic Changes Are Important IndicatorsEmail this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
A study by Norwegian researchers published November 13 in the open-access journal PLoS Genetics reports that cervical cancer patients with specific changes in the cancer genome have a three- or fourfold increased risk of relapse after standard treatment compared to patients without these changes. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 13, 2009 Category: Consumer Health News Tags: cervical cancer / HPV Vaccine Source Type: news
Disease Progression And Survival Of Cervical Cancer Patients: Genetic Changes Are Important IndicatorsEmail this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
A study by Norwegian researchers published November 13 in the open-access journal PLoS Genetics reports that cervical cancer patients with specific changes in the cancer genome have a three- or fourfold increased risk of relapse after standard treatment compared to patients without these changes. Research suggests that specific genetic changes are critical steps in the progression of the disease towards an aggressive and treatment-resistant state. (Source: Cancer / Oncology News From Medical News Today)
Source: Cancer / Oncology News From Medical News Today - November 13, 2009 Category: Cancer & Oncology Tags: cervical cancer / HPV Vaccine Source Type: news
Gene Dosage, Expression, and Ontology Analysis Identifies Driver Genes in the Carcinogenesis and Chemoradioresistance of Cervical CancerEmail this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
Author Summary
Genetic gains and losses, i.e. changes in gene dosages, are common abnormalities of human cancers. Discovering these defects and understanding the biological meaning can lead to improved therapeutic opportunities. This paper reports a large scale screening of gene dosage alterations in cervical cancer and gives a broader exploration of the expression and function of genes with gains or losses. We have focused on the most frequent gene dosage alterations and the alterations associated with survival after chemoradiotherapy, since these defects are likely to be of major importance for developing disease. The m...
Source: PLoS Genetics - November 13, 2009 Category: Genetics & Stem Cells Authors: Malin Lando et al. Source Type: journals
Medicare approves FDG-PET for cervical cancer stagingEmail this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
Medical imagers can now expect Medicare to routinely cover FDG-PET for initial staging of cervical cancer, thanks to a national coverage ruling announced Nov. 10. (Source: Diagnostic Imaging)
Source: Diagnostic Imaging - November 12, 2009 Category: Radiology Source Type: info
Motor Protein-Dependent Membrane Trafficking of KCl Cotransporter-4 Is Important for Cancer Cell InvasionEmail this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
This study stresses the important role of KCC4 in tumor malignant behavior. Real-time reverse transcription-PCR on samples collected by laser microdissection and immunofluorescent stainings with different KCC isoform antibodies indicate that KCC4 is abundant in metastatic cervical and ovarian cancer tissues. Insulin-like growth factor I (IGF-I) and epidermal growth factor (EGF) stimulate KCC4 recruitment from a presumably inactive cytoplasmic pool of endoplasmic reticulum and Golgi to plasma membrane along actin cytoskeleton that is significantly inhibited by LY294002 and wortmannin. Throughout the trafficking process, KCC...
Source: Cancer Research - November 12, 2009 Category: Cancer & Oncology Authors: Chen, Y.-F., Chou, C.-Y., Wilkins, R. J., Ellory, J. C., Mount, D. B., Shen, M.-R. Tags: Cell, Tumor, and Stem Cell Biology Source Type: journals
Epigenetic Silencing of Interferon-{kappa} in Human Papillomavirus Type 16-Positive CellsEmail this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
We have investigated interferon- (IFN-) regulation in the context of human papillomavirus (HPV)–induced carcinogenesis using primary human foreskin keratinocytes (HFK), immortalized HFKs encoding individual oncoproteins of HPV16 (E6, E7, and E6/E7), and cervical carcinoma cells. Here, IFN- was suppressed in the presence of E6, whereas its expression was not affected in HFKs or E7-immortalized HFKs. Transcription could be reactivated after DNA demethylation but was decreased again upon drug removal. Partial reactivation could also be accomplished when E6 was knocked down, suggesting a contribution of E6 in IFN- de nov...
Source: Cancer Research - November 12, 2009 Category: Cancer & Oncology Authors: Rincon-Orozco, B., Halec, G., Rosenberger, S., Muschik, D., Nindl, I., Bachmann, A., Ritter, T. M., Dondog, B., Ly, R., Bosch, F. X., Zawatzky, R., Rosl, F. Tags: Molecular Biology, Pathobiology, and Genetics Source Type: journals
SNM applauds expanded medicare coverage for cervical cancerEmail this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
(Society of Nuclear Medicine) SNM applauds the Centers for Medicare & Medicaid Services' (CMS) decision to lift restrictions and expand coverage of PET scans for women with cervical cancer. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 12, 2009 Category: Global & Universal Source Type: news
Genetic changes shown to be important indicators for disease progression in cervical cancer patientsEmail this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
(Public Library of Science) Cervical cancer patients with specific changes in the cancer genome have a three- or fourfold increased risk of relapse after standard treatment compared to patients without these changes, according to a study by Norwegian researchers published November 13 in the open-access journal PLoS Genetics. The research suggests that specific genetic changes are crucial steps in the progression of the disease towards an aggressive and treatment-resistant state. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - November 12, 2009 Category: Global & Universal Source Type: news
Clinical-Dosimetric Analysis of Measures of Dysphagia including Gastrostomy-tube Dependence among Head and Neck Cancer Patients Treated Definitively by Intensity-Modulated Radiotherapy with Concurrent ChemotherapyEmail this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
Conclusion:
Our analysis suggests that adhering to the following parameters may decrease the risk of prolonged GT dependence and dysphagia: IPC V65 < 15%, IPC V60 < 40%, IPC Dmean < 55 Gy, and CPI Dmax < 60 Gy. (Source: Radiation Oncology)
Source: Radiation Oncology - November 12, 2009 Category: Cancer & Oncology Authors: Baoqing LiDan LiDerick LauD FarwellQuang LuuDavid RockeKathleen NewmanJean CourquinJames PurdyAllen Chen Source Type: journals
Cannabidiol Inhibits Cancer Cell Invasion Via Upregulation Of Tissue Inhibitor Of Matrix Metalloproteinases-1.Email this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
Although cannabinoids exhibit a broad variety of anticarcinogenic effects, their potential use in cancer therapy is limited by their psychoactive effects. Here we evaluated the impact of cannabidiol, a plant-derived non-psychoactive cannabinoid, on cancer cell invasion. Using Matrigel invasion assays we found a cannabidiol-driven impaired invasion of human cervical cancer (HeLa, C33A) and human lung cancer cells (A549) that was reversed by antagonists to both CB(1) and CB(2) receptors as well as to transient receptor potential vanilloid 1 (TRPV1). The decrease of invasion by cannabidiol appeared concomitantly with upre...
Source: Biochemical Pharmacology - November 12, 2009 Category: Drugs & Pharmacology Authors: Ramer R, Merkord J, Rohde H, Hinz B Tags: Biochem Pharmacol Source Type: journals
Erratum: Corrections to Multidentate Small-Molecule Inhibitors of Vaccinia H1-Related (VHR) Phosphatase Decrease Proliferation of Cervix Cancer CellsEmail this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry)
Source: Journal of Medicinal Chemistry - November 11, 2009 Category: Chemistry Tags: article Source Type: journals
Heat shock protein 110 improves the anti-tumor effects of the cytotoxic T lymphocyte epitope E7(49-57) in mice.Email this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
Several strategies have been used to enhance the vaccine-induced immunity of peptide vaccines and effective therapeutic benefits, including the utilization of heat shock proteins (HSP), especially the HSP70 family. HSP110 exhibits a higher binding affinity with protein and is capable of enhancing the immunogenicity of protein antigens; however, whether HSP110 can also increase the efficiency of peptide vaccine remains unclear. Here, we investigated mHSP110 as a chaperone immunoadjuvant to enhance the immune response to HPV16 oncoprotein E7-derived CTL epitope E7(49-57) in a mouse model. We developed the HSP110-E7(49-57...
Source: Cancer Biology and Therapy - November 11, 2009 Category: Cancer & Oncology Authors: Ren F, Xu Y, Mao L, Ou R, Ding Z, Zhang X, Tang J, Li B, Jia Z, Tian Z, Ni B, Wu Y Tags: cancer Biol Ther Source Type: journals
