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Is Type 2 Diabetes Mellitus A Risk Factor For Gallbladder, Biliary And Pancreatic Cancer?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
There are minimal data assessing the relationship between diabetes and gallbladder, biliary and pancreatic cancer. Recent small studies have suggested an elevated risk of pancreatic cancer only in patients with diabetes mellitus (DM). A research article published on November 14, 2009 in the World Journal of Gastroenterology addresses this question. The research team, lead by Dr. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 20, 2009 Category: Consumer Health News Tags: Diabetes Source Type: news

Obesity and CancerEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Exp Clin Endocrinol Diabetes 2009; 117: 563-566DOI: 10.1055/s-0029-1241870AbstractEpidemiological studies have suggested that obesity is associated with increased risk of several cancer types including colon, esophagus, breast (in postmenopausal women), endometrium, kidney, liver, gallbladder and pancreas. Suggested mechanisms include increased intake of potentially carcinogenic food ingredients along with excessive amount of calories, loss of cancer protective effects due to reduced physical activity, carcinogenic factors released from increased adipose tissue mass and “secondary” associations via “precu...
Source: Experimental and Clinical Endocrinology and Diabetes - November 19, 2009 Category: Endocrinology Tags: Mini-Review Source Type: journals

Is type 2 diabetes mellitus a risk factor for gallbladder, biliary and pancreatic cancer?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(World Journal of Gastroenterology) Presently, type 2 diabetes mellitus (DM) is associated with cardiovascular complications, and also with several cancers. A research group from USA has investigated the association of gallbladder, biliary and pancreatic cancer in hospitalized American veterans with and without type 2 DM. Among patients with type 2 DM, the risk of pancreatic cancer was threefold higher and that for gallbladder and extrahepatic biliary cancer was twofold higher compared to hospitalized patients without DM. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 18, 2009 Category: Global & Universal Source Type: news

Carcinoid tumors and small-cell carcinomas of the gallbladder and extrahepatic bile ducts: a comparative study based on 221 cases from the Surveillance, Epidemiology, and End Results ProgramEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract: Primary neuroendocrine tumors of the gallbladder (GB) and extrahepatic biliary ducts (EHBDs) include carcinoid tumors and small-cell carcinomas (SCCs). They are uncommon, and therefore, little is known about their demographics and clinical course. From National Cancer Institute's Surveillance, Epidemiology, and End Results program (1973-2005), we analyzed the demographics and 10-year relative survival rates of carcinoids and SCCs of the GB and EHBD according to histologic type and stage. There were 119 cases of carcinoid tumors and 54 cases of SCCs in the GB. There were 31 carcinoid tumors and 17 SCCs in the EHBD...
Source: Annals of Diagnostic Pathology - November 16, 2009 Category: Pathology Authors: Jorge Albores-Saavedra, Kristen Batich, Sarah Hossain, Donald E. Henson, Arnold M. Schwartz Tags: Original Contributions Source Type: journals

Diabetes mellitus as a risk factor for gastrointestinal cancer among American veterans.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: Our study demonstrated that patients with DM have a threefold increased risk for developing pancreatic cancer and a twofold risk for developing biliary cancer. PMID: 19908334 [PubMed - in process] (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - November 13, 2009 Category: Gastroenterology Authors: Jamal MM, Yoon EJ, Vega KJ, Hashemzadeh M, Chang KJ Tags: World J Gastroenterol Source Type: journals

Fatal gemcitabine-induced pulmonary toxicity in metastatic gallbladder adenocarcinomaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In this report, we describe a fatal gemcitabine-induced pulmonary toxicity in a patient with gallbladder metastatic adenocarcinoma. A 72-year-old patient was submitted to an elective laparoscopic cholecystectomy, and a tubular adenocarcinoma in the gallbladder was incidentally diagnosed. CT scan and ultrasound before the surgery did not show any tumor. After the surgery a Pet scan was positive for a hot-spot in the left colon. The colonic lesion was conveniently removed and the histology evaluation confirmed the diagnosis of adenocarcinoma tubular. The patient was then submitted to three sections of 1,600 mg/m2 of gem...
Source: Cancer Chemotherapy and Pharmacology - November 10, 2009 Category: Cancer & Oncology Tags: cancer Chemotherapy and Pharmacology Source Type: journals

Unsuspected Gallbladder Cancer Diagnosed After Laparoscopic Cholecystectomy: Focus on Acute CholecystitisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions The preoperative diagnosis included a high rate of acute and severe acute cholecystitis. Survival was not associated with the presence of AC and bile spillage. Therefore, we suggest that AC may not influence the prognosis of unsuspected gallbladder cancer after LC. Moreover, good tumor differentiation can guarantee favorable survival, even in UGC with AC. Content Type Journal ArticleDOI 10.1007/s00268-009-0279-9Authors Ji Hun Kim, Ajou University Department of Surgery, School of Medicine San-5, Wonchondong, Yeongtonggu Suwon 442-749 KoreaWook Hwan Kim, Ajou University Department of Surgery...
Source: World Journal of Surgery - November 7, 2009 Category: Surgery Tags: World Journal of Surgery Source Type: journals

Detection of Helicobacter hepaticus in Human Bile Samples of Patients with Biliary DiseaseEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: Helicobacter hepaticus may closely associate with diseases of the liver and biliary tract in humans. (Source: Helicobacter)
Source: Helicobacter - November 4, 2009 Category: Gastroenterology Authors: Toshihide Hamada, Kenji Yokota, Kiyoshi Ayada, Kazuyuki Hirai, Tomoari Kamada, Ken Haruma, Kazuaki Chayama, Keiji Oguma Tags: ORIGINAL ARTICLES Source Type: journals

A Case of Gallbladder Cancer Arising from the Rokitansky-Aschoff SinusEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Japanese Journal of Clinical Oncology)
Source: Japanese Journal of Clinical Oncology - November 2, 2009 Category: Cancer & Oncology Authors: Matsumoto, T., Shimada, K. Tags: Image of the Month Source Type: journals

Cholangiocarcinoma may be familial and associated with malignant melanomaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We describe a family with familial cancer of the gallbladder and melanoma. Further descriptions may lead to a better delineation of a hereditary component in adenocarcinoma of the gallbladder. (Source: European Journal of Surgical Oncology)
Source: European Journal of Surgical Oncology - October 16, 2009 Category: Cancer & Oncology Authors: Patrick Morrison, D. Donnelly Tags: Abstracts Source Type: journals

Radical resection for T1b gallbladder cancer: a decision analysisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Decision analysis demonstrates that radical resection is associated with increased survival for most patients with T1b gallbladder cancer. (Source: HPB: official journal of the International Hepato Pancreat Biliary Association)
Source: HPB: official journal of the International Hepato Pancreat Biliary Association - October 14, 2009 Category: Gastroenterology Authors: Michael A. Abramson, Pari Pandharipande, Daniel Ruan, Jason S. Gold, Edward E. Whang Source Type: journals

Incidental Gallbladder Cancer Diagnosed Following Laparoscopic CholecystectomyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions Male patients exhibited aggressive tumor characteristics. Laparoscopic cholecystectomy is an adequate treatment for pT1 tumors. For pT2 and pT3 patients, additional radical surgery might be needed to achieve a tumor-free surgical margin, along with lymph node dissection. Content Type Journal ArticleDOI 10.1007/s00268-009-0249-2Authors Sae Byeol Choi, Korea University Guro Hospital Department of Surgery, Korea University Medical Center, Korea University College of Medicine 80, Gurodong, Guro-gu Seoul KoreaHyung Joon Han, Korea University Guro Hospital Department of Surgery, Korea University...
Source: World Journal of Surgery - October 13, 2009 Category: Surgery Tags: World Journal of Surgery Source Type: journals

First experience of hepatic radioembolization using microspheres labelled with yttrium-90 (TheraSphere): practical aspects concerning its implementationEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion Although sometimes technically difficult, the use of TheraSphere microspheres is a worthwhile therapeutic approach because of the low level exposure of operators and the encouraging rate of response or stabilization. The use of SPECT/CT contributes greatly to helping therapeutic planning, especially in the learning curve or when the angiographic procedure is difficult. Content Type Journal ArticleCategory Short CommunicationDOI 10.1007/s00259-009-1279-6Authors Etienne Garin, Comprehensive Cancer Center Eugène Marquis Department of Nuclear Medicine Rennes FranceYan Rolland, Comprehensive Ca...
Source: European Journal of Nuclear Medicine and Molecular Imaging - October 10, 2009 Category: Radiology Tags: European Journal of Nuclear Medicine and Molecular Imaging Source Type: journals

The role of PET-CT in patients with incidental gallbladder cancerEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: For patients presenting with stage T1b or greater IGC, the use of 18FDG PET-CT will help reduce the number of patients undergoing non-therapeutic re-exploration and may help to determine the likely prognosis. 18FDG PET-CT might be a useful tool for the selection of patients for potentially curative treatment. (Source: HPB: official journal of the International Hepato Pancreat Biliary Association)
Source: HPB: official journal of the International Hepato Pancreat Biliary Association - October 9, 2009 Category: Gastroenterology Authors: Jean M. Butte, Francisca Redondo, Enrique Waugh, Manuel Meneses, Rossana Pruzzo, Hugo Parada, Horacio Amaral, Hernán A. De La Fuente Source Type: journals

Histone deacetylase inhibitor (SAHA) and repression of EZH2 synergistically inhibit proliferation of gallbladder carcinomaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In conclusion, this study suggests a possible mechanism by which carcinoma cells but not normal cells are sensitive to SAHA and indicates the efficacy of this new anticancer agent in combination with EZH2 repression in gallbladder carcinoma. (Cancer Sci 2009) (Source: Cancer Science)
Source: Cancer Science - October 6, 2009 Category: Cancer & Oncology Authors: Junpei Yamaguchi, Motoko Sasaki, Yasunori Sato, Keita Itatsu, Kenichi Harada, Yoh Zen, Hiroko Ikeda, Yuji Nimura, Masato Nagino, Yasuni Nakanuma Source Type: journals

New book reveals secret Brazilian Aloe recipe for curing cancer using just three ingredientsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(NaturalNews) Living in South America, I often find myself steeped in abundant natural cures for many diseases, including cancer. You can hardly walk out your front door without finding yourself surrounded with natural medicines made by Mother Nature, and it's true across the continent, from Ecuador (where I live) through Peru and Bolivia, and all the way to Brazil.In Brazil, a humble monk named Father Romano Zago has uncovered a powerful yet simple cure for cancer based on just three ingredients... one of them being whole Aloe Arborescens (not just the gel, but the whole leaf, including the skin and the sap). What follows...
Source: NaturalNews.com - October 2, 2009 Category: Consumer Health Advice Source Type: news

Can aloe vera prevent and cure cancer?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(NaturalNews) If you're looking to prevent cancer, you need to know about aloe vera. More resarch on aloe vera is taking place all around the world as word spreads about its natural healing potential. You'll learn a wealth of information about this in this article.Here, we present a collection of quotes and observations about aloe vera and cancer, documented in some of the best health books ever written. Read and remember these quotes, and feel free to share what you learn here with others who may also need this information.Some clinics have used aloe vera to increase the effectiveness of cancer treatment with the chemothe...
Source: NaturalNews.com - October 1, 2009 Category: Consumer Health Advice Source Type: news

A case of unresectable gallbladder cancer responding to gemcitabine after metallic biliary stent implantation.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A 69-year-old woman with a chief complaint of jaundice was referred to our hospital. She underwent exploratory laparotomy under a diagnosis of advanced biliary tract cancer. Histological examination of a biopsy specimen of the gallbladder revealed adenocarcinoma. The tumor was unresectable because of invasion into a wide area of the hepatoduodenal ligament and liver bed. Retrograde transhepatic bile drainage tubes were inserted through the common bile duct into the right and left branches of the intrahepatic bile ducts. After metallic biliary stent implantation, gemcitabine (1,000 mg) was administered intravenously onc...
Source: Journal of Nippon Medical School - October 1, 2009 Category: Universities & Medical Training Authors: Matsutani T, Uchida E, Yokoyama T, Matsushita A, Matsuda A, Sasajima K Tags: J Nippon Med Sch Source Type: journals

Macabre autopsy misdiagnosed mummy's cause of deathEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A macabre 19th century autopsy of the mummy of a 50-year-old woman named Irtyersenu misdiagnosed her cause of deathThe mysterious death of an Egyptian woman, whose mummy became a public spectacle in Georgian Britain, has been solved by a team of researchers in London.Forensic analysis of tissues taken from the 2,600-year-old corpse has revealed signs of tuberculosis, a disease that was widespread in Egypt.The mummy of Irtyersenu or "lady of the house" became the first to go under the surgeon's knife in an autopsy in 1825, when England was in the grip of mummy mania.The remains were unveiled to a large crowd in a macabre le...
Source: Guardian Unlimited Science - September 29, 2009 Category: Science Authors: Ian Sample Tags: Science Archaeology UK news World news Egypt Medical research The Guardian Source Type: news

Macabre autopsy led to misdiagnosisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A macabre 19th century autopsy of the mummy of a 50-year-old woman named Irtyersenu misdiagnosed her cause of deathThe mysterious death of an Egyptian woman, whose mummy became a public spectacle in Georgian Britain, has been solved by a team of researchers in London.Forensic analysis of tissues taken from the 2,600-year-old corpse has revealed signs of tuberculosis, a disease that was widespread in Egypt.The mummy of Irtyersenu or "lady of the house" became the first to go under the surgeon's knife in an autopsy in 1825, when England was in the grip of mummy mania.The remains were unveiled to a large crowd in a macabre le...
Source: Guardian Unlimited Science - September 29, 2009 Category: Science Authors: Ian Sample Tags: Science Archaeology UK news World news Egypt Medical research The Guardian Source Type: news

CholangiocarcinomaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
is a rare, primary cancer of the biliary tree that can be difficult to diagnose with all imaging modalities. The presenting clinical symptoms of nausea, vomiting, and jaundice can be consistent with classic cholecystitis symptoms, increasing the risk of a missed diagnosis. The most often seen risk factor for cholangiocarcinoma is primary sclerosing cholangitis (PSC). In most cases, the initial diagnostic finding is intrahepatic ductal dilatation. Once an actual mass is seen, liver transplantation is the necessary treatment plan because of likely hepatic metastasis. There is a slight recurrence rate of cholangiocarcinoma e...
Source: Journal of Diagnostic Medical Sonography - September 29, 2009 Category: Radiology Authors: Whitlock, P. J. Tags: Articles Source Type: journals

Lymph node evaluation is associated with improved survival after surgery for early stage gallbladder cancerEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: LN evaluation is a critical component of radical resection for GB cancer. In the absence of LN evaluation, radical resection provides no benefit over cholecystectomy alone. (Source: Surgery)
Source: Surgery - September 28, 2009 Category: Surgery Authors: Eric H. Jensen, Anasooya Abraham, Stephanie Jarosek, Elizabeth B. Habermann, Waddah B. Al-Refaie, Selwyn A. Vickers, Beth A. Virnig, Todd M. Tuttle Tags: Central Surgical Association Source Type: journals

EGFR and HER2 expression in advanced biliary tract cancer.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: Our data suggest that routine testing and therapeutic targeting of HER2 does not seem to be useful in patients with BTC, while targeting EGFR may be promising. PMID: 19777609 [PubMed - in process] (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - September 26, 2009 Category: Gastroenterology Authors: Harder J, Waiz O, Otto F, Geissler M, Olschewski M, Weinhold B, Blum HE, Schmitt-Graeff A, Opitz OG Tags: World J Gastroenterol Source Type: journals

Identification of transforming activity of free fatty acid receptor 2 by retroviral expression screeningEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Gallbladder cancer (GBC) is a highly fatal malignancy in humans. Genetic alterations in KRAS or TP53 as well as overexpression of ERBB2 have been shown to contribute to the development of certain types of GBC. However, many cases of GBC do not harbor such genetic changes, with other transforming events awaiting discovery. We here tried to identify novel cancer-promoting genes in GBC, with the use of a retroviral cDNA expression library. A retroviral cDNA expression library was constructed from a surgically resected clinical specimen of GBC, and was used to infect 3T3 fibroblasts in a focus formation assay. cDNA incorporate...
Source: Cancer Science - September 24, 2009 Category: Cancer & Oncology Authors: Hisashi Hatanaka, Mamiko Tsukui, Shuji Takada, Kentaro Kurashina, Young Lim Choi, Manabu Soda, Yoshihiro Yamashita, Hidenori Haruta, Toru Hamada, Toshihide Ueno, Kiichi Tamada, Yoshinori Hosoya, Naohiro Sata, Yoshikazu Yasuda, Hideo Nagai, Kentaro Sugano, Source Type: journals

Complement Receptor 1 (A3650G RsaI and Intron 27 HindIII) Polymorphisms and Risk of Gallbladder Cancer in North Indian PopulationEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Decreased expression due to genetic variations in complement receptor 1 (CR1) on erythrocytes might result in reduced clearance of immune complexes, conferring interindividual variation for gallbladder cancer (GBC) susceptibility. We studied role of CR1 (A3650G RsaI and Intron 27 HindIII) polymorphisms in gallstone disease and GBC in north Indian population. Study included 185 GBC patients, 185 gallstone patients and 200 controls. Genotyping was done by PCR-RFLP. Result showed GG genotype and G allele of CR1 A3650G RsaI were conferring significant risk for GBC [(P = 0.022; OR = 1.94; 95% CI = 1.1[ndash]3.4) and (P = 0.035;...
Source: Scandinavian Journal of Immunology - September 24, 2009 Category: Allergy & Immunology Authors: A. Srivastava, B. Mittal Tags: CLINICAL IMMUNOLOGY Source Type: journals

Should the extrahepatic bile duct be resected or preserved in R0 radical surgery for advanced gallbladder carcinoma? Results of a Japanese Society of Biliary Surgery Survey: A multicenter studyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions Our retrospective questionnaire survey showed that an extrahepatic bile duct resection had no preventive value in some patients with advanced gallbladder carcinoma in comparison to similar patients who had no such bile duct resection. An extrahepatic bile duct resection may therefore be unnecessary in advanced gallbladder carcinoma without a direct infiltration of the hepatoduodenal ligament and the cystic duct. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00595-009-3960-6Authors Tatsuo Araida, Tokyo Women’s Medical University Department of Surgery, Institute of Gas...
Source: Surgery Today - September 23, 2009 Category: Surgery Tags: Surgery Today Source Type: journals

Incidental Gallbladder Carcinoma Diagnosed During or After Laparoscopic CholecystectomyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions The survival with incidental GC is related to stage, and it validates that a carefully performed LC is adequate treatment for carcinoma in situ, and stage 1a and b cancer. A frozen section examination was helpful but did not provide a definitive diagnosis. Meticulous techniques during LC, including retrieval of the gallbladder in a retrieval bag, may prevent port-site recurrence and intraperitoneal dissemination. Content Type Journal ArticleDOI 10.1007/s00268-009-0218-9Authors Wei-Jie Zhang, 101th Hospital of Chinese People’s Liberation Army Department of General Surgery North Xingyuan ...
Source: World Journal of Surgery - September 17, 2009 Category: Surgery Tags: World Journal of Surgery Source Type: journals

Iliac–hepatic arterial bypass for compromised collateral flow during modified Appleby operation for advanced pancreatic cancerEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We described a modified Appleby operation for locally advanced distal pancreatic cancer with compromised hepatic collateral flow that needed hepatic arterial revascularization, successfully accomplished by left external iliac–hepatic arterial bypass with Dacron prosthesis. Patient recovery was uneventful and he was discharged on the 10th postoperative day. Postoperative angio-CT disclosed a patent arterial bypass. Patient is well and asymptomatic 13 months after operation. At the time of this writing, postoperative CT scan showed no evidence of disease and CA 19-9 level is normal. There is a well established rationale to...
Source: European Journal of Surgical Oncology - September 14, 2009 Category: Cancer & Oncology Authors: M.A. Machado, R.C. Surjan, K. Nishinari, F.F. Makdissi, M.C. Machado Tags: Technical Article Source Type: journals

The Gerson Therapy: Big Pharma and the AMA Suppress Another Holistic Cancer CureEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
ConclusionAs Albert Schweitzer wrote, "Many of his basic ideas have been adopted without having his name connected with them." That was written several years ago. Today, there are those who have used the Gerson protocol to cure their cancer and become alternative cancer treatment gurus, soliciting materials over the Internet.There are also those who have adopted some or most of his techniques in their holistic health practices. His discoveries have spread throughout the alternative healing community. But it's probably best to use a practitioner who has been certified by the Gerson Institute for cancer cases.Fortunately, pa...
Source: NaturalNews.com - September 10, 2009 Category: Consumer Health Advice Source Type: news

[Extrapancreatic tumors in intraductal papillary mucinous neoplasm of the pancreas.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: IPMN is associated with high incidence of extrapancreatic tumors, particularly gastric and colorectal neoplasms. Upper gastrointestinal endoscopy and colonoscopy should be done, and systemic surveillance for the possible occurrence of other tumors may allow early detection of extrapancreatic tumor in patients with IPMN. PMID: 19844152 [PubMed - in process] (Source: Korean J Gastroenter...)
Source: Korean J Gastroenter... - August 31, 2009 Category: Gastroenterology Authors: Oh SJ, Lee SJ, Lee HY, Paik YH, Lee DK, Lee KS, Chung JB, Yu JS, Yoon DS Tags: Korean J Gastroenterol Source Type: journals

Early gallbladder cancer: Is further treatment necessary?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The goal of this study was to evaluate a series of patients with early gallbladder cancer, focusing on the selection of treatment and the role of Rokitansky Aschoff sinus infiltration.We performed a retrospective analysis of a prospective series of 371 patients with gallbladder cancer. Specimens were reviewed by an independent pathologist to confirm the diagnosis and depth of infiltration and to evaluate the presence of Rokitansky Aschoff sinus involvement.Forty-nine and 45 patients with muscular (pT1b) and mucosal (pT1a) infiltration gallbladder cancer tumors were studied respectively. Simple cholecystectomy was the treat...
Source: Journal of Surgical Oncology - August 30, 2009 Category: Cancer & Oncology Authors: Xabier de Aretxabala, Ivan Roa, Juan Hepp, Fernando Maluenda, Gerardo Mordojovich, Jorge Leon, Juan Carlos Roa Source Type: journals

Multicenter, phase II study of gemcitabine and S-1 combination chemotherapy in patients with advanced biliary tract cancerEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions Gemcitabine and S-1 combination chemotherapy has promising efficacy and good tolerability in patients with advanced biliary tract cancer. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00280-009-1115-5Authors Takashi Sasaki, University of Tokyo Department of Gastroenterology, Faculty of Medicine 7-3-1 Hongo, Bunkyo-ku Tokyo 113-8655 JapanHiroyuki Isayama, University of Tokyo Department of Gastroenterology, Faculty of Medicine 7-3-1 Hongo, Bunkyo-ku Tokyo 113-8655 JapanYousuke Nakai, University of Tokyo Department of Gastroenterology, Faculty of Medicine 7-3-1 Hongo, Bunky...
Source: Cancer Chemotherapy and Pharmacology - August 25, 2009 Category: Cancer & Oncology Tags: cancer Chemotherapy and Pharmacology Source Type: journals

[Gallbladder cancer in a regional hospital.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: GBC has a low incidence but it will be found in 1% of cholecystectomies. There is no adjuvant treatment and T-based surgical treatment is the is the only opportunity to reach cure in those patients. A national GBC database would be helpful in the publication of national guidelines for this disease. PMID: 19695566 [PubMed - as supplied by publisher] (Source: Cirugia eEspanola)
Source: Cirugia eEspanola - August 17, 2009 Category: Surgery Authors: Morera Ocón FJ, Ballestín Vicente J, Ripoll Orts F, Landete Molina F, García-Granero Ximénez M, Millán Tarín J, Tursi Rispoldi LD, Bernal Sprekelsen JC Tags: Cir Esp Source Type: journals

The epothilone B analogue ixabepilone in patients with advanced hepatobiliary cancers: a trial of the University of Chicago Phase II ConsortiumEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion Single agent ixabepilone has limited activity in advanced hepatobiliary cancers. Content Type Journal ArticleCategory PHASE II STUDIESDOI 10.1007/s10637-009-9297-6Authors Halla S. Nimeiri, Northwestern University Feinberg School of Medicine, Robert H. Lurie Comprehensive Cancer Center 676 North St. Clair Street, suite 850 Chicago IL 60611 USADeepti A. Singh, University of Chicago Medical Center 5841 S. Maryland Ave., MC 2115 Chicago IL 60637 USAKristen Kasza, University of Chicago 5841 S. Maryland Ave. MC 2007 Chicago IL 60637 USADavid A. Taber, Northern Indiana Cancer Research Consortium 100Navarre Place S...
Source: Investigational New Drugs - August 11, 2009 Category: Drugs & Pharmacology Tags: Investigational New Drugs Source Type: journals

Value of Routine Histopathologic Examination of Three Common Surgical Specimens: Appendix, Gallbladder, and HemorrhoidEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions The routine histopathology examination of the appendix and gallbladder, particularly in cases of empyema and patient’s age over 60 years, is of value for identifying unsuspected conditions requiring further postoperative management. However, routine histopathologic evaluation of the hemorrhoid seems unnecessary. Content Type Journal ArticleDOI 10.1007/s00268-009-0164-6Authors Varut Lohsiriwat, Mahidol University Department of Surgery, Faculty of Medicine Siriraj Hospital Prannok Road Bangkok 10700 ThailandAkkarash Vongjirad, Mahidol University Department of Surgery, Faculty of Medic...
Source: World Journal of Surgery - August 9, 2009 Category: Surgery Tags: World Journal of Surgery Source Type: journals

Gemcitabine and oxaliplatin in patients with unresectable biliary cancer including gall bladder cancer: a Korean Cancer Study Group phase II trialEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions The GEMOX regimen demonstrated a modest antitumor activity and is well tolerated in patients with advanced BTCs. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00280-009-1069-7Authors Joung-Soon Jang, Chung-Ang University College of Medicine Division of Hematology/Oncology, Department of Internal Medicine 224 Heukseok-dong, Dongjak-gu Seoul 156-755 Republic of KoreaHo Yeong Lim, Sungkyunkwan University School of Medicine Divisions of Hematology-Oncology, Department of Medicine, Samsung Medical Center 50 Ilwon-dong, Kangnam-gu Seoul 135-710 Republic of KoreaIn Gyu Hwang, Yo...
Source: Cancer Chemotherapy and Pharmacology - August 3, 2009 Category: Cancer & Oncology Tags: cancer Chemotherapy and Pharmacology Source Type: journals

Gastric Emptying Function in Patients 5 Years After Pylorus-Preserving Distal Gastrectomy With or Without Preserving Pyloric and Hepatic Branches of the Vagal Nerve for Early Gastric CancerEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions There were no significant differences in the postoperative QOL and GET between PPG patients with preserving PHV and those without preserving PHV. Cholecystolithiasis was only found in patients without preserving PHV. Content Type Journal ArticleDOI 10.1007/s00268-009-0147-7Authors Ryouichi Tomita, Nippon Dental University School of Life Dentistry at Tokyo Department of Surgery 2-3-16 Fujimi, Chiyoda-ku Tokyo 102-8158 Japan Journal World Journal of SurgeryOnline ISSN 1432-2323Print ISSN 0364-2313 (Source: World Journal of Surgery)
Source: World Journal of Surgery - August 3, 2009 Category: Surgery Tags: World Journal of Surgery Source Type: journals

Uncommon mucosal metastases to the stomachEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: While the accurate recognition of these lesions at endoscopy is fraught with difficulty, pathological awareness of such uncommon metastases in the gastric mucosa is essential for accurate diagnosis and optimal patient management. (Source: World Journal of Surgical Oncology)
Source: World Journal of Surgical Oncology - August 2, 2009 Category: Cancer & Oncology Authors: R KanthanK SharanowskiJ SengerF JenniferR ChibbarSc Kanthan Source Type: journals

Use of Retrieval Bags in Incidental Gallbladder Cancer CasesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions According to the registry data, the intraoperative gallbladder perforation results in significant (P = 0.047) prognostic disadvantage and in these cases retrieval bags were used more often (P = 0.001). However, in IGBC cases if intraoperative gallbladder perforation has already happened, the use of retrieval bags had no protective effects. Content Type Journal ArticleDOI 10.1007/s00268-009-0163-7Authors Thorsten Oliver Goetze, Ketteler-Krankenhaus Department of Surgery 63071 Offenbach GermanyVittorio Paolucci, Ketteler-Krankenhaus Department of Surgery 63071 Offenbach Ge...
Source: World Journal of Surgery - July 28, 2009 Category: Surgery Tags: World Journal of Surgery Source Type: journals

Gallbladder cancerEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
— Comprehensive overview covers symptoms, treatment of cancer of the gallbladder. Sponsored by:Chemotherapy.com - http://www.chemotherapy.com (Source: MayoClinic.com Full Feed)
Source: MayoClinic.com Full Feed - July 25, 2009 Category: Consumer Health News Source Type: news

Apply Influence Diagrams for Utility Analysis of Paying the Weight-Reducing Expenses: A Case Study in TaiwanEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract To effectively control the growth of medical expenditure, Bureau of National Health Insurance (NHI) of Taiwan has taken many measures, including the Reasonable Number of Outpatient Services, Ceiling Price, Global Budgets, Strategic Analysis and the Excellence Plan; however, these measures can only scratch the surface. Due to the change of life style and the deteriorating condition of over-nutrition and obesity, people now have a higher risk of diabetes, hypertension, hyperlipidemia, cardiovascular disease, gallbladder disease, cancer, gout, arthritis, and so on, which leads to higher medical expendi...
Source: Journal of Medical Systems - July 25, 2009 Category: Information Technology Tags: Journal of Medical Systems Source Type: journals

Indirect method to estimate specific Hispanic group cancer ratesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion The approach yielded reasonable and useful information to explore etiologic differences among the populations, as well as to develop relevant cancer control interventions. However, direct identification of specific Hispanic ethnicity in medical records and annual Census estimates of these populations would be preferable if they ever became available. Content Type Journal ArticleCategory Original paperDOI 10.1007/s10552-009-9398-8Authors Holly L. Howe, North American Association of Central Cancer Registries, Inc. Springfield IL USAAndrew Lake, Information Management Services, Inc. Silver Spr...
Source: Cancer Causes and Control - July 21, 2009 Category: Cancer & Oncology Tags: cancer Causes and Control Source Type: journals

Metachronous bile duct cancer nine years after resection of gallbladder cancer.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report a rare case of a 74-year-old man with metachronous gallbladder cancer and bile duct cancer who underwent curative resection twice, with the operations nine years apart. At the age of 65 years, the patient underwent a cholecystectomy and resection of the liver bed for gallbladder cancer. This was a well-differentiated adenocarcinoma, with negative resection margins (T2N0M0, stage IB). Nine years later, during a follow-up examination, abdominal computed tomography and MRCP showed an enhanced 1.7 cm mass in the hilum that extended to the second branch of the right intrahepatic bile duct. We diagnosed this lesion as ...
Source: World Journal of Gastroenterology : WJG - July 20, 2009 Category: Gastroenterology Authors: Joo HJ, Kim GH, Jeon WJ, Chae HB, Park SM, Youn SJ, Choi JW, Sung R Tags: World J Gastroenterol Source Type: journals

Autoimmune pancreatitis: An underdiagnosed autoimmune disease with clinical, imaging and serological features.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Since Sarles et al reported a case of pancreatitis associated with hypergammaglobulinemia, many cases have been described, which led to the current concept of "autoimmune pancreatitis (AIP)". Lymphoplasmacytic infiltration and fibrosis on histology together with elevated IgG levels or the presence of autoantibodies on laboratory examinations supported the concept of AIP. In recent years, based on histological and immunohistochemical examination of various organs of patients with AIP, a novel clinicopathological entity, IgG4-related slerosing disease, has been proposed. AIP is a systemic disease that is characterized by...
Source: Autoimmunity Reviews - July 17, 2009 Category: Allergy & Immunology Authors: Sánchez-Castañón M, de Las Heras-Castaño G, López-Hoyos M Tags: Autoimmun Rev Source Type: journals

Update to Patient UK recordsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We have updated our collection of Patient UK links. Newly added resources are: Acute diarrhoea in children Alcohol and liver disease Aminosalicylates Antacids Antispasmodic drugs Cholecystitis Cirrhosis Constipation in children Dyspepsia in pregnancy Gastroenteritis in children Gilbert's syndrome Haemochromatosis Hepatitis A immunisation Obstetric cholestasis Primary biliary cirrhosis Primary liver cancer Proton pump inhibitors (PPIs) Pyloric stenosis Screening for colorectal (bowel) cancer Sickness and vomiting of pregnancy Stomach (gastric) ulcer Threadworms Toddler's diarrhoea Ulcerative colitis Wilson's disease (Sourc...
Source: Gastroenterology and Liver Diseases Specialist Library - Biliary tree and gallbladder - July 14, 2009 Category: Gastroenterology Source Type: organizations

Screening pharmaceuticals for possible carcinogenic effects: initial positive results for drugs not previously screenedEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions These preliminary findings suggest that further studies are indicated regarding sulindac, hyoscyamine, nortriptyline, oxazepam, fluoxetine, paroxetine, hydrochlorothiazide, and nifedipine. Content Type Journal ArticleCategory Original paperDOI 10.1007/s10552-009-9375-2Authors Gary D. Friedman, Kaiser Permanente Medical Care Program Division of Research 2000 Broadway Oakland CA 94612 USANatalia Udaltsova, Kaiser Permanente Medical Care Program Division of Research 2000 Broadway Oakland CA 94612 USAJames Chan, Kaiser Permanente Medical Care Program Pharmacy Outcomes Research Group 1800 Harris...
Source: Cancer Causes and Control - July 7, 2009 Category: Cancer & Oncology Tags: cancer Causes and Control Source Type: journals

Gallbladder cancerEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Last updated 5 February 2008.This section tells you about gallbladder cancer. It includes early symptoms, causes and diagnosis, tests and treatment, living with gallbladder cancer, and current research. (Source: Gastroenterology and Liver Diseases Specialist Library - Biliary tree and gallbladder)
Source: Gastroenterology and Liver Diseases Specialist Library - Biliary tree and gallbladder - July 7, 2009 Category: Gastroenterology Source Type: organizations