Exploration of the molecular mechanism guiding Xinfeng capsule regulatory mechanism for rheumatoid arthritis inflammation
CONCLUSIONS: XFC could effectively improve the clinical inflammatory indexes of RA. The active ingredients of XFC improved the inflammatory state of RA by regulating the TLR-signaling pathway.PMID:38586085 | PMC:PMC10994809 | DOI:10.62347/TPOQ4910 (Source: American Journal of Translational Research)
Source: American Journal of Translational Research - April 8, 2024 Category: Research Authors: Ziheng Zhu Lei Wan Source Type: research

The impact of the COVID-19 pandemic on the mental health of patients diagnosed with inflammatory bowel diseases
In conclusion, the emergence of a novel viral pathogen represents a significant distress factor for patients with autoimmune diseases. Recognizing and comprehending these consequences enhances our understanding of the intricate interplay between physical and mental health and equips authorities with valuable insights to better manage future epidemics or viral outbreaks. This study underscores the importance of tailored support systems and strategies for patients with autoimmune diseases during global health crises.PMID:38585531 | PMC:PMC10994603 | DOI:10.25122/jml-2023-0475 (Source: Journal of Medicine and Life)
Source: Journal of Medicine and Life - April 8, 2024 Category: General Medicine Authors: Oliviu-Florentiu Sarb Vitalie Vacaras Vladimir-Petru Filip Adriana-Daniela Sarb Roxana-Delia Zaharie Nicu Draghici Dafin-Fior Muresanu Alina-Ioana Tantau Source Type: research

Exploration of the molecular mechanism guiding Xinfeng capsule regulatory mechanism for rheumatoid arthritis inflammation
CONCLUSIONS: XFC could effectively improve the clinical inflammatory indexes of RA. The active ingredients of XFC improved the inflammatory state of RA by regulating the TLR-signaling pathway.PMID:38586085 | PMC:PMC10994809 | DOI:10.62347/TPOQ4910 (Source: American Journal of Translational Research)
Source: American Journal of Translational Research - April 8, 2024 Category: Research Authors: Ziheng Zhu Lei Wan Source Type: research

The impact of the COVID-19 pandemic on the mental health of patients diagnosed with inflammatory bowel diseases
In conclusion, the emergence of a novel viral pathogen represents a significant distress factor for patients with autoimmune diseases. Recognizing and comprehending these consequences enhances our understanding of the intricate interplay between physical and mental health and equips authorities with valuable insights to better manage future epidemics or viral outbreaks. This study underscores the importance of tailored support systems and strategies for patients with autoimmune diseases during global health crises.PMID:38585531 | PMC:PMC10994603 | DOI:10.25122/jml-2023-0475 (Source: Journal of Medicine and Life)
Source: Journal of Medicine and Life - April 8, 2024 Category: General Medicine Authors: Oliviu-Florentiu Sarb Vitalie Vacaras Vladimir-Petru Filip Adriana-Daniela Sarb Roxana-Delia Zaharie Nicu Draghici Dafin-Fior Muresanu Alina-Ioana Tantau Source Type: research

Exploration of the molecular mechanism guiding Xinfeng capsule regulatory mechanism for rheumatoid arthritis inflammation
CONCLUSIONS: XFC could effectively improve the clinical inflammatory indexes of RA. The active ingredients of XFC improved the inflammatory state of RA by regulating the TLR-signaling pathway.PMID:38586085 | PMC:PMC10994809 | DOI:10.62347/TPOQ4910 (Source: American Journal of Translational Research)
Source: American Journal of Translational Research - April 8, 2024 Category: Research Authors: Ziheng Zhu Lei Wan Source Type: research

MiR-574-5p activates human TLR8 to promote autoimmune signaling and lupus
Endosomal single-stranded RNA-sensing Toll-like receptor-7/8 (TLR7/8) plays a pivotal role in inflammation and immune responses and autoimmune diseases. However, the mechanisms underlying the initiation of the... (Source: Cell Communication and Signaling)
Source: Cell Communication and Signaling - April 8, 2024 Category: Molecular Biology Authors: Tao Wang, Dan Song, Xuejuan Li, Yu Luo, Dianqiang Yang, Xiaoyan Liu, Xiaodan Kong, Yida Xing, Shulin Bi, Yan Zhang, Tao Hu, Yunyun Zhang, Shuang Dai, Zhiqiang Shao, Dahan Chen, Jinpao Hou & hellip; Tags: Research Source Type: research

A case of autoimmune pulmonary alveolar proteinosis during the course of treatment of rapidly progressive interstitial pneumonia associated with anti-MDA5 antibody-positive dermatomyositis
Autoimmune pulmonary alveolar proteinosis (APAP) is a diffuse lung disease that causes abnormal accumulation of lipoproteins in the alveoli; however, its pathogenesis remains unclear. Recently, APAP cases have... (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - April 8, 2024 Category: Respiratory Medicine Authors: Masakiyo Yatomi, Keiichi Akasaka, Shintaro Sato, Mizuki Chida, Mio Kanbe, Hiru Sawada, Itaru Yokota, Ikuo Wakamatsu, Sohei Muto, Mari Sato, Kochi Yamaguchi, Yosuke Miura, Hiroaki Tsurumaki, Reiko Sakurai, Kenichiro Hara, Yasuhiko Koga & hellip; Tags: Case Report Source Type: research

Tertiary lymphoid structures in head and neck squamous cell carcinoma
This article will review the formation, prognosis, and predictive value of TLS as well as inducing TLS neogenesis in HNSCC.PMID:38583352 | DOI:10.1016/j.tranon.2024.101949 (Source: Translational Oncology)
Source: Translational Oncology - April 7, 2024 Category: Cancer & Oncology Authors: Jing Zhu Hui Lu Kongcheng Wang Baorui Liu Jing Yan Source Type: research

Noncriteria antiphospholipid antibodies in antiphospholipid syndrome
Int J Lab Hematol. 2024 Apr 7. doi: 10.1111/ijlh.14268. Online ahead of print.ABSTRACTAntiphospholipid syndrome (APS) is an autoimmune disease characterized by thrombotic manifestations and/or obstetric complications in patients with persistently positive antiphospholipid antibodies (aPL). aPL are a heterogeneous group of autoantibodies, but only lupus anticoagulant, anticardiolipin (aCL), and antibeta2-glycoprotein I antibodies (aβ2GPI) IgG or IgM are included as laboratory classification criteria. Seronegative APS patients are usually defined as patients with the clinical symptoms of APS but who test negative for aPL. T...
Source: International Journal of Laboratory Hematology - April 7, 2024 Category: Hematology Authors: Katrien M J Devreese Source Type: research

Immunoregulatory natural killer cells
Clin Chim Acta. 2024 Apr 5:117896. doi: 10.1016/j.cca.2024.117896. Online ahead of print.ABSTRACTThis review discusses a broader scope of functional roles for NK cells. Despite the well-known cytolytic and inflammatory roles of NK cells against tumors and pathogenic diseases, extensive evidence demonstrates certain subsets of NK cells have defacto immunoregulatory effects and have a role in inducing anergy or lysis of antigen-activated T cells and regulating several autoimmune diseases. Furthermore, recent evidence suggests certain subsets of immunoregulatory NK cells can cause anergy or lysis of antigen-activated T cells ...
Source: International Journal of Clinical Chemistry - April 7, 2024 Category: Chemistry Authors: Kevin Roe Source Type: research

Tertiary lymphoid structures in head and neck squamous cell carcinoma
This article will review the formation, prognosis, and predictive value of TLS as well as inducing TLS neogenesis in HNSCC.PMID:38583352 | DOI:10.1016/j.tranon.2024.101949 (Source: Translational Oncology)
Source: Translational Oncology - April 7, 2024 Category: Cancer & Oncology Authors: Jing Zhu Hui Lu Kongcheng Wang Baorui Liu Jing Yan Source Type: research

Noncriteria antiphospholipid antibodies in antiphospholipid syndrome
Int J Lab Hematol. 2024 Apr 7. doi: 10.1111/ijlh.14268. Online ahead of print.ABSTRACTAntiphospholipid syndrome (APS) is an autoimmune disease characterized by thrombotic manifestations and/or obstetric complications in patients with persistently positive antiphospholipid antibodies (aPL). aPL are a heterogeneous group of autoantibodies, but only lupus anticoagulant, anticardiolipin (aCL), and antibeta2-glycoprotein I antibodies (aβ2GPI) IgG or IgM are included as laboratory classification criteria. Seronegative APS patients are usually defined as patients with the clinical symptoms of APS but who test negative for aPL. T...
Source: International Journal of Laboratory Hematology - April 7, 2024 Category: Hematology Authors: Katrien M J Devreese Source Type: research

Immunoregulatory natural killer cells
Clin Chim Acta. 2024 Apr 5:117896. doi: 10.1016/j.cca.2024.117896. Online ahead of print.ABSTRACTThis review discusses a broader scope of functional roles for NK cells. Despite the well-known cytolytic and inflammatory roles of NK cells against tumors and pathogenic diseases, extensive evidence demonstrates certain subsets of NK cells have defacto immunoregulatory effects and have a role in inducing anergy or lysis of antigen-activated T cells and regulating several autoimmune diseases. Furthermore, recent evidence suggests certain subsets of immunoregulatory NK cells can cause anergy or lysis of antigen-activated T cells ...
Source: International Journal of Clinical Chemistry - April 7, 2024 Category: Chemistry Authors: Kevin Roe Source Type: research

Tertiary lymphoid structures in head and neck squamous cell carcinoma
This article will review the formation, prognosis, and predictive value of TLS as well as inducing TLS neogenesis in HNSCC.PMID:38583352 | DOI:10.1016/j.tranon.2024.101949 (Source: Translational Oncology)
Source: Translational Oncology - April 7, 2024 Category: Cancer & Oncology Authors: Jing Zhu Hui Lu Kongcheng Wang Baorui Liu Jing Yan Source Type: research

Noncriteria antiphospholipid antibodies in antiphospholipid syndrome
Int J Lab Hematol. 2024 Apr 7. doi: 10.1111/ijlh.14268. Online ahead of print.ABSTRACTAntiphospholipid syndrome (APS) is an autoimmune disease characterized by thrombotic manifestations and/or obstetric complications in patients with persistently positive antiphospholipid antibodies (aPL). aPL are a heterogeneous group of autoantibodies, but only lupus anticoagulant, anticardiolipin (aCL), and antibeta2-glycoprotein I antibodies (aβ2GPI) IgG or IgM are included as laboratory classification criteria. Seronegative APS patients are usually defined as patients with the clinical symptoms of APS but who test negative for aPL. T...
Source: International Journal of Laboratory Hematology - April 7, 2024 Category: Hematology Authors: Katrien M J Devreese Source Type: research