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The Early and Delayed Analgesic Effects of Ketamine After Total Hip Arthroplasty: A Prospective, Randomized, Controlled, Double-Blind Study.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: Ketamine had a morphine-sparing effect after THA, even when morphine was combined with multimodal systemic analgesia. It also facilitated rehabilitation at 1 mo and decreased postoperative chronic pain up to 6 mo after surgery. PMID: 19923527 [PubMed - as supplied by publisher] (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - November 20, 2009 Category: Anesthesiology Authors: Remérand F, Le Tendre C, Baud A, Couvret C, Pourrat X, Favard L, Laffon M, Fusciardi J Tags: Anesth Analg Source Type: journals

The Effect of Single-Dose Propofol Injection on Pain and Quality of Life in Chronic Daily Headache: A Randomized, Double-Blind, Controlled Trial.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: A single IV infusion of propofol 2.4 mg/kg produces a statistically significant, but not clinically meaningful, reduction in disability from CDH 30 days after infusion and does not reduce pain intensity or analgesic use. This study does not support this regimen of IV propofol for clinical management of CDH. PMID: 19923528 [PubMed - as supplied by publisher] (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - November 20, 2009 Category: Anesthesiology Authors: Simmonds MK, Rashiq S, Sobolev IA, Dick BD, Gray DP, Stewart BJ, Jamieson-Lega KI Tags: Anesth Analg Source Type: journals

Improvement in Psychosocial Outcomes in Chronic Pain Patients Receiving Intrathecal Morphine Infusions.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: IT infusion of morphine using an implantable pump was helpful in improving psychosocial function in patients with intractable pain that had failed to respond to standard multimodal analgesic therapy. PMID: 19923529 [PubMed - as supplied by publisher] (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - November 20, 2009 Category: Anesthesiology Authors: Duse G, Davià G, White PF Tags: Anesth Analg Source Type: journals

A Transdermal Nicotine Patch Is Not Effective for Postoperative Pain Management in Smokers: A Pilot Dose-Ranging Study.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: Transdermal nicotine, 5-15 mg, failed to relieve postoperative pain or reduce opioid use in smokers. PMID: 19923530 [PubMed - as supplied by publisher] (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - November 20, 2009 Category: Anesthesiology Authors: Olson LC, Hong D, Conell-Price JS, Cheng S, Flood P Tags: Anesth Analg Source Type: journals

Epidural Space Identification: A Meta-Analysis of Complications After Air Versus Liquid as the Medium for Loss of Resistance.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: Larger studies that overcome limitations of heterogeneity across studies and a relatively infrequent occurrence of complications are required to determine the optimal medium for loss of resistance during epidural block. PMID: 19923534 [PubMed - as supplied by publisher] (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - November 20, 2009 Category: Anesthesiology Authors: Schier R, Guerra D, Aguilar J, Pratt GF, Hernandez M, Boddu K, Riedel B Tags: Anesth Analg Source Type: journals

Nutra Pharma Introduces Chronic Pain Reliever, Nyloxin OTC, for International DistributionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Nutra Pharma has introduced Nyloxin OTC, an over-the-counter pain reliever, that will be marketed and sold through international distribution channels alongside the Company's prescription pain reliever, Nyloxin Rx. (PRWeb Nov 19, 2009) Read the full story at http://www.prweb.com/releases/Nutra_Pharma/Nyloxin_OTC/prweb3231994.htm (Source: PRWeb: Medical Pharmaceuticals)
Source: PRWeb: Medical Pharmaceuticals - November 20, 2009 Category: Pharmaceuticals Source Type: news

Stem Cells May Be Used as Skin GraftsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Title: Stem Cells May Be Used as Skin GraftsCategory: Health NewsCreated: 11/20/2009 11:01:00 AMLast Editorial Review: 11/20/2009 11:01:19 AM (Source: MedicineNet Chronic Pain General)
Source: MedicineNet Chronic Pain General - November 20, 2009 Category: Anesthesiology Source Type: consumer

Accuracy and Efficacy of Intrathecal Administration of Morphine Sulfate for Treatment of Intractable Pain Using the Prometra® Programmable PumpEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions. The Prometra pump provides an accurate, effective, and safe system for intrathecal administration of morphine sulfate for treatment of chronic intractable pain. (Source: Neuromodulation)
Source: Neuromodulation - November 20, 2009 Category: Neurology Authors: Richard Rauck, Timothy Deer, Steve Rosen, Gurpreet Padda, John Barsa, Elmer Dunbar, Gopala Dwarakanath Source Type: journals

Novel Approach for Peripheral Subcutaneous Field Stimulation for the Treatment of Severe, Chronic Knee Joint Pain After Total Knee ArthroplastyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions. Introduction of a peripheral subcutaneous field stimulation directly to the painful knee area is a novel and simple procedure that was extremely effective for the relief of pain and may provide a breakthrough in the treatment of chronic intractable knee pain following total knee arthroplasty. The periarticular approach has several advantages, including only small incisions over the lateral and medial knee, proximal thigh and abdomen resulting in minimal strain on the lead array with flexion and extension contributing to overall stability of this system. (Source: Neuromodulation)
Source: Neuromodulation - November 20, 2009 Category: Neurology Authors: William Porter McRoberts, Martin Roche Source Type: journals

Altered rectal sensory response induced by balloon distention in patients with functional abdominal pain syndromeEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: An inconsistency of visceral sensitivity between lower and higher pressure distention might be a key feature for understanding the pathogenesis of FAPS. (Source: BioPsychoSocial Medicine)
Source: BioPsychoSocial Medicine - November 20, 2009 Category: Psychiatry & Psychology Authors: Tsukasa NozuMiwako Kudaira Source Type: journals

62-Year-Old Man Becomes First Patient In China Implanted With Rechargeable Neurostimulator For Chronic PainEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
St. Jude Medical, Inc. (NYSE:STJ) announced that a 62-year-old man from Shenzhen, Guangdong province has become the first patient in China to be implanted with the Eon™ neurostimulator, a rechargeable device used to help manage chronic pain. Despite prior back surgeries, the patient suffered from chronic back pain for more than a decade. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 19, 2009 Category: Consumer Health News Tags: pain / Anesthetics Source Type: news

62-Year-Old Man Becomes First Patient In China Implanted With Rechargeable Neurostimulator For Chronic PainEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
St. Jude Medical, Inc. (NYSE:STJ) announced that a 62-year-old man from Shenzhen, Guangdong province has become the first patient in China to be implanted with the Eon™ neurostimulator, a rechargeable device used to help manage chronic pain. Despite prior back surgeries, the patient suffered from chronic back pain for more than a decade. (Source: Pain / Anesthetics News From Medical News Today)
Source: Pain / Anesthetics News From Medical News Today - November 19, 2009 Category: Anesthesiology Tags: pain / Anesthetics Source Type: news

Recent CDC report shows Chlamydia on the riseEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The Lowdown on STD’s: Chlamydia Chlamydia is the third most common sexually transmitted infection (STI) in the United States. It is the most common bacteria causing an STI. According to a 2007 Center for Disease Control report, South Carolina ranks 3rd out of the 50 states in chlamydial infections. Those at most risk of infection are single, minority women between ages 15-21 with new or multiple sexual partners. However, Chlamydia affects women and men of all backgrounds. Like all sexually transmitted infections, Chlamydia enters a woman’s body during intercourse. Chl...
Source: Women Speak - November 19, 2009 Category: OBGYN Authors: My name Tags: Infectious Disease Gynecological Health Sex & Relationships Source Type: consumer

Common pain relief medication may encourage cancer growthEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Although morphine has been the gold-standard treatment for postoperative and chronic cancer pain for two centuries, a growing body of evidence is showing that opiate-based painkillers can stimulate the growth and spread of cancer cells. Two new studies advance that argument and demonstrate how shielding lung cancer cells from opiates reduces cell proliferation, invasion and migration in both cell-culture and mouse models. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - November 19, 2009 Category: Science Source Type: news

Treatment of Chronic Mandibular Dislocations: A Comparison Between Eminectomy and MiniplatesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: Eminectomy had less chance of recurrence without creating articular damage, and with miniplates, the chance of recurrence increased because there is always the possibility of the miniplate fracturing. (Source: Journal of Oral and Maxillofacial Surgery)
Source: Journal of Oral and Maxillofacial Surgery - November 19, 2009 Category: ENT & OMF Authors: Belmiro Cavalcanti do Egito Vasconcelos, Gabriela Granja Porto Tags: Basic and Patient-Oriented Research Source Type: journals

Coronary Artery Aneurysm Formation Within New-Generation Bare-Metal Stents: Not Just Due to Drug Elution!Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A 57-year-old woman with chronic stable angina underwent uncomplicated stenting in the left anterior descending artery (LAD) and right coronary artery (RCA) (A) with excellent results in the target vessel. Coronary angiogram repeated for atypical chest pain 6 months later demonstrated coronary artery aneurysm (CAA) (arrowheads) within the segments stented with a bare-metal stent (BMS) in both arteries (B), confirmed on intravascular ultrasound examination (C). Arrows show the extent of the aneurysm as seen on the intravascular ultrasound images. The RCA segment stented with the everolimus-eluting stent Xience (Abbott Labor...
Source: Journal of the American College of Cardiology - November 19, 2009 Category: Cardiology Authors: Sudipta Chattopadhyay, Timothy Kinnaird, Richard A. Anderson Tags: IMAGES IN CARDIOLOGY Source Type: journals

Common Pain Relief Medication May Encourage Cancer GrowthEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Although morphine has been the gold-standard treatment for postoperative and chronic cancer pain for two centuries, a growing body of evidence is showing that opiate-based painkillers can stimulate the growth and spread of cancer cells. Two new studies advance that argument and demonstrate how shielding lung cancer cells from opiates reduces cell proliferation, invasion and migration in both cell-culture and mouse models. (Source: Pain / Anesthetics News From Medical News Today)
Source: Pain / Anesthetics News From Medical News Today - November 19, 2009 Category: Anesthesiology Tags: Cancer / Oncology Source Type: news

Common Pain Relief Medication May Encourage Cancer GrowthEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Although morphine has been the gold-standard treatment for postoperative and chronic cancer pain for two centuries, a growing body of evidence is showing that opiate-based painkillers can stimulate the growth and spread of cancer cells. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 19, 2009 Category: Consumer Health News Tags: Cancer / Oncology Source Type: news

Morphine may stimulate cancer growthEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Eventhough morphine has been the gold-standard therapy for postoperative and chronic cancer pain for two centuries, a growing body of evidence is showing that opiate-based painkillers can stimulate the growth and spread of cancer cells. Two new studies advance that argument and demonstrate how shielding lung cancer cells from opiates reduces cell proliferation, invasion and migration in both cell-culture and mouse models........ (Source: Medicineworld.org: New Article Alert)
Source: Medicineworld.org: New Article Alert - November 19, 2009 Category: Consumer Health News Source Type: info

[Reconstructive surgery for Charcot foot : Long-term 5-year outcome.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: By using a fixateur externe many amputations could be avoided and patient's activity could be improved. The interdisciplinary teamwork between an orthopedic surgeon, orthopedic shoemaker and orthopedic technician is essential for long term success. PMID: 19921507 [PubMed - as supplied by publisher] (Source: Der Orthopade)
Source: Der Orthopade - November 19, 2009 Category: Orthopaedics Authors: Illgner U, Podella M, Rümmler M, Wühr J, Büsch HG, Wetz HH Tags: Orthopade Source Type: journals

Conditional gene deletion reveals functional redundancy of GABAB receptors in peripheral nociceptors in vivoEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: This study addressed contribution of GABAB receptors expressed on primary afferent nociceptive fibers to the modulation of pain. We observed that neither the development of acute and chronic pain nor the analgesic effects of a systematically-delivered GABAB agonist was significantly changed upon a specific deletion of GABAB receptors from peripheral nociceptive neurons in vivo. This lets us conclude that GABAB receptors in the peripheral nervous system play a less important role than those in the central nervous system in the regulation of pain. (Source: Molecular Pain)
Source: Molecular Pain - November 19, 2009 Category: Molecular Biology Authors: Vijayan GangadharanNitin AgarwalStefan BruggerImgard TegederBernhard BettlerRohini KunerMartina Kurejova Source Type: journals

Swine flu vaccine uptakeEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Several newspapers have reported that pregnant women and other vulnerable people are refusing to have the swine flu vaccine. The Times reported that a poll of GPs found that only 46% of people who were offered the vaccine have accepted it, and one doctor estimated that only 5% of pregnant women have had it. The news reports are based on a “snapshot” survey of 107 GPs. The survey asked how likely they were to hit the government’s target of vaccinating at least half of their patients who are under 65 and in high-risk groups this winter. GPs were also asked to estimate how many of the people who were offered the vacci...
Source: NHS News Feed - November 18, 2009 Category: Consumer Health News Tags: Swine flu Source Type: news

Chronic Mesenteric Ischemia: Diagnosis and TreatmentEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Semin intervent Radiol 2009; 26: 345-351DOI: 10.1055/s-0029-1242198ABSTRACTChronic mesenteric ischemia is a rare condition, generally characterized by postprandial abdominal pain. Although chronic mesenteric ischemia accounts for only a small percentage of all mesenteric ischemic events, it can have significant clinical consequences. There are multiple etiologies; however, the most common cause is atherosclerosis. The diagnosis of chronic mesenteric ischemia requires a high clinical index of suspicion. An imaging study can confirm the presence of a stenosis or occlusion involving the mesenteric vessels in patients who are ...
Source: Seminars in Interventional Radiology - November 18, 2009 Category: Radiology Source Type: journals

Breast Cancer Treatment Leaves Patients With Chronic PainEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Long after patients complete their treatments for breast cancer, many still experience lingering pain and discomfort. Danish researchers found that nearly half of the breast cancer survivors they surveyed... (Source: OncologySTAT What Patients Are Reading)
Source: OncologySTAT What Patients Are Reading - November 18, 2009 Category: Cancer & Oncology Source Type: info

62-Year-Old Man Becomes First Patient in China Implanted with Rechargeable Neurostimulator for Chronic PainEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
St. Jude Medical receives Chinese State Food and Drug Administration approval for Eon and Genesis neurostimulators for chronic pain ST. PAUL, Minn., Nov 18--(HSMN NewsFeed)--St. Jude Medical, Inc. (NYSE:STJ ) announced today that a 62-year-old man from ... DevicesSt. Jude Medical, Eon neurostimulator, rechargeable neurostimulator (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - November 18, 2009 Category: Pharmaceuticals Source Type: news

Pregabalin, celecoxib, and their combination for treatment of chronic low-back painEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions Combination of celecoxib and pregabalin is more effective than monotherapy for chronic low-back pain, with similar adverse effects. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s10195-009-0077-zAuthors Carlo Luca Romanò, Istituto Ortopedico I.R.C.C.S. Galeazzi Via Riccardo Galeazzi, 4 20166 Milan ItalyDelia Romanò, Istituto Ortopedico I.R.C.C.S. Galeazzi Via Riccardo Galeazzi, 4 20166 Milan ItalyCristina Bonora, Istituto Ortopedico I.R.C.C.S. Galeazzi Via Riccardo Galeazzi, 4 20166 Milan ItalyGiuseppe Mineo, Università degli Studi di Milano Istituto Ortopedico I.R.C.C...
Source: Journal of Orthopaedics and Traumatology - November 18, 2009 Category: Orthopaedics Tags: Journal of Orthopaedics and Traumatology Source Type: journals

Qutenza Approved for Post-Shingles Nerve PainEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Title: Qutenza Approved for Post-Shingles Nerve PainCategory: Health NewsCreated: 11/17/2009 12:10:00 PMLast Editorial Review: 11/18/2009 (Source: MedicineNet Chronic Pain General)
Source: MedicineNet Chronic Pain General - November 18, 2009 Category: Anesthesiology Source Type: consumer

Role of GABA(A) receptors in cognition.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Complex brains have developed specialized mechanisms for the grouping of principal cells into temporal coalitions of local or distant networks: the inhibitory interneuron 'clocking' networks. They consist of GABAergic (where GABA is gamma-aminobutyric acid) interneurons of a rich diversity. In cortical circuits, these neurons control spike timing of the principal cells, sculpt neuronal rhythms, select cell assemblies and implement brain states. On the basis of these considerations, the deficits in cognition, emotion and perception in psychiatric disorders such as anxiety, depression or schizophrenia are considered to m...
Source: Biochemical Society Transactions - November 18, 2009 Category: Biochemistry Authors: Möhler H Tags: Biochem Soc Trans Source Type: journals

Common pain relief medication may encourage cancer growthEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(University of Chicago Medical Center) Although morphine has been the gold-standard treatment for postoperative and chronic cancer pain for two centuries, a growing body of evidence is showing that opiate-based painkillers can stimulate the growth and spread of cancer cells. Two new studies advance that argument and demonstrate how shielding lung cancer cells from opiates reduces cell proliferation, invasion and migration in both cell-culture and mouse models. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - November 18, 2009 Category: Cancer & Oncology Source Type: news

Incidence of oral mucositis, its treatment and pain management in patients receiving cancer treatment at Radiation Oncology Departments in Spanish hospitals (MUCODOL Study)Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions Pain due to OM, a common complication of chemotherapy and radiation, limits nutritional intake and oral function. Analgesia protocols need to be assessed to improve the quality of life of these patients. Content Type Journal ArticleCategory Research ArticlesDOI 10.1007/s12094-009-0422-yAuthors Ana Mañas, Hospital Universitario de La Paz Radiation Oncology Department Paseo de la Castellana. 261 ES-28046 Madrid SpainAmalia Palacios, Hospital Reina Sofía Radiation Oncology Department Córdoba SpainJorge Contreras, Hospital Carlos Haya Radiation Oncology Department Málaga SpainIsabel Sánche...
Source: Clinical and Translational Oncology - November 18, 2009 Category: Cancer & Oncology Tags: Clinical and Translational Oncology Source Type: journals

The gait and balance of patients with diabetes can be improved: a randomised controlled trialEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions/interpretation Specific training can improve gait speed, balance, muscle strength and joint mobility in diabetic patients. Further studies are needed to explore the influence of these improvements on the number of reported falls, patients’ physical activity levels and quality of life. Trial registration: ClinicalTrials.gov NCT00637546 Funding: This work was supported by the Swiss National Foundation (SNF): PBSKP-123446/1/ Content Type Journal ArticleCategory ArticleDOI 10.1007/s00125-009-1592-4Authors L. Allet, Maastricht University and Caphri Research...
Source: Diabetologia - November 18, 2009 Category: Endocrinology Tags: Diabetologia Source Type: journals

Oxaliplatin-induced loss of phosphorylated heavy neurofilament subunit neuronal immunoreactivity in rat DRG tissueEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Background: Oxaliplatin and related chemotherapeutic drugs cause painful chronic peripheral neuropathies in cancer patients. We investigated changes in neuronal size profiles and neurofilament immunoreactivity in L5 dorsal root ganglion (DRG) tissue of adult female Wistar rats after multiple-dose treatment with oxaliplatin, cisplatin, carboplatin or paclitaxel. Results: After treatment with oxaliplatin, phosphorylated neurofilament heavy subunit (pNF-H) immunoreactivity was reduced in neuronal cell bodies, but unchanged in nerve fibres, of the L5 DRG. Morphometric analysis confirmed significant changes in the number (-75%;...
Source: Molecular Pain - November 18, 2009 Category: Molecular Biology Authors: Stephen JamiesonJoshuan SubramaniamJohnson LiuNancy JongVirginia IpBronwen ConnorMark McKeage Source Type: journals

A descriptive report of management strategies used by chiropractors, as reviewed by a single independent chiropractic consultant in the Australian workers compensation system.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: It is essential chiropractic practitioners perform reasonably necessary treatment to reduce dependency on passive treatment, increase compliance to active care programs and reduce the progression to chronic pain states. It is recommended that common findings be integrated into further research to expedite and refine the management of patients with an occupational injury. (Source: Chiropractic & Osteopathy)
Source: Chiropractic & Osteopathy - November 18, 2009 Category: Complementary Medicine Authors: Henry PollardKatie de Luca Source Type: journals

Mutual influence of posttraumatic stress disorder symptoms and chronic pain among injured accident survivors: A longitudinal studyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The relationship between acute stress disorder (ASD), posttraumatic stress disorder symptoms (PTSD), and chronic pain was investigated in a longitudinal study of injured accident victims (N = 323, 64.7% men). Assessments took place 5 days (T1), 6 (T2) months, and 12 (T3) months postaccident. Relations between pain and posttraumatic stress symptoms were tested by structural equation modeling. Subjects diagnosed with full or subsyndromal PTSD at T2 and at T3 (14 and 19%) reported significantly higher pain intensity. Cross-lagged panel analysis yielded a mutual maintenance of pain intensity and ASD or PTSD symptoms across T2....
Source: Journal of Traumatic Stress - November 18, 2009 Category: Psychiatry & Psychology Authors: J. Jenewein, L. Wittmann, H. Moergeli, J. Creutzig, U. Schnyder Source Type: journals

Can chronic neuropathic pain following thoracic surgery be predicted during the postoperative period? [Institutional report - Thoracic oncologic]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Chronic pain following thoracic surgery is common and associated with neuropathic symptoms, however, the proportion of patients with neuropathic pain in the immediate postoperative period is unknown. We aimed to determine the proportion of patients who have neuropathic symptoms and signs immediately after, and at three months following thoracic surgery. The study was designed as a prospective observational cohort study. We identified patients with pain of predominantly neuropathic origin using the Leeds Assessment of Neuropathic Symptoms and Signs (LANSS) score in the immediate postoperative period and the self-report LANS...
Source: Interactive CardioVascular and Thoracic Surgery - November 17, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Searle, R. D., Simpson, M. P., Simpson, K. H., Milton, R., Bennett, M. I. Tags: Institutional report - Thoracic oncologic Source Type: journals

Malignant pleural effusion in the presence of trapped lung. Five-year experience of PleurX tunnelled catheters [Institutional report - Thoracic oncologic]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We describe our five-year experience with the use of indwelling PleurX catheters in patients with malignant pleural effusions in the presence of confirmed trapped lung on radiological or VATS investigation. Patient health related quality of life was investigated by telephone questionnaire. The parameters analysed were symptomatic relief, mobility and ease of management following insertion. One hundred and sixteen patients underwent PleurX catheter insertion by a single operator, 48 questionnaires were completed. Of the 48 cases analysed, improvement in all three quality of life indices was recorded following catheter inser...
Source: Interactive CardioVascular and Thoracic Surgery - November 17, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Efthymiou, C. A., Masudi, T., Charles Thorpe, J. A., Papagiannopoulos, K. Tags: Institutional report - Thoracic oncologic Source Type: journals

The role of the primary care physician during the active treatment phase.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Although more research needs to be done to determine the optimal role for PCPs during the active phase of cancer treatment, patients, PCPs, and oncologists all see a significant role for primary care in the care of patients with cancer. In the United States, family physicians are actively involved in the care of cancer patients, especially in provision of support, education, and care of intercurrent illness and chronic disease. Fatigue, depression, pain, and psychosocial distress are important symptoms that should be screened for and addressed. The PCP should be aware of adverse effects of chemotherapy and radiation an...
Source: Primary Care - November 17, 2009 Category: Primary Care Authors: Smith GF, Toonen TR Tags: Prim Care Source Type: journals

Reduction in pain sensitivity from pharmacological elevation of blood pressure in persons with chronically low blood pressure.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Recent studies have revealed evidence for increased pain sensitivity in individuals with chronically low blood pressure. The present trial explored whether pain sensitivity can be reduced by pharmacological elevation of blood pressure. Effects of the sympathomimetic midodrine on threshold and tolerance to heat pain were examined in 52 hypotensive persons (mean blood pressure 96/61 mmHg) based on a randomized, placebo-controlled, double-blind design. Heat stimuli were applied to the forearm via a contact thermode. Confounding of drug effects on pain perception with changes in skin temperature, temperature sensitivity, and m...
Source: Journal of Psychophysiology - November 17, 2009 Category: Psychiatry & Psychology Authors: Duschek, Stefan; Heiss, Heike; Buechner, Boriana; Schandry, Rainer Source Type: journals

Lord Sainsbury lecture series: Found in translation – a cure for painEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
For many people chronic pain can be incapacitating but thankfully new developments in neuroscience are providing scientists with a better understanding of the condition. A free lecture tonight [17 November] at the University of Bristol by Professor Clifford Woolf, a leading Harvard scientist, will explore pain and how neuroscience research is helping to alleviate it. (Source: University of Bristol news)
Source: University of Bristol news - November 17, 2009 Category: Universities & Medical Training Authors: news_text Tags: Press releases Source Type: organizations

CKS topic review: Low back painEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Source: CKS Area: Evidence > Guidelines This Topic Review from the Clinical Knowledge Service (CKS) covers the management of acute and chronic low back pain. It covers: . the management in primary care of non-specific low back pain without radiculopathy (sciatica) that has lasted less than about 6 weeks, and . the management in primary care of non-specific low back pain without radiculopathy (sciatica) that has lasted more than about 6 weeks. (Source: NeLM - Pain control)
Source: NeLM - Pain control - November 17, 2009 Category: Anesthesiology Source Type: organizations

Quantification of a Methadone Metabolite (EDDP) in Urine: Assessment of Compliance.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion For the first time, urine analyses may be used to monitor methadone over- or under-use in a clinical setting, regardless of the state of patient hydration or the manipulation of a sample by addition of another substance, such as bleach, soap, or even methadone, which could render an appropriate sample inappropriate or an inappropriate sample appropriate. A similar approach may prove useful for other drug treatments, allowing for more accurate monitoring of commonly abused prescription medications. PMID: 19920164 [PubMed - as supplied by publisher] (Source: Clin Med Res)
Source: Clin Med Res - November 17, 2009 Category: Research Authors: Larson ME, Richards TM Tags: Clin Med Res Source Type: journals

Letrozole combined with norethisterone acetate compared with norethisterone acetate alone in the treatment of pain symptoms caused by endometriosisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS The combination drug regimen was more effective in reducing pain and deep dyspareunia than norethisterone acetate; however, letrozole caused a higher incidence of adverse effects, cost more and did not improve patients' satisfaction or influence recurrence of pain. (Source: Human Reproduction)
Source: Human Reproduction - November 16, 2009 Category: Reproduction Medicine Authors: Ferrero, S., Camerini, G., Seracchioli, R., Ragni, N., Venturini, P.L., Remorgida, V. Tags: Gynaecology Source Type: journals

Nutra Pharma Announces Plans to Begin Drug Registration Process in South America for its Over-the-Counter Pain RelieverEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Nutra Pharma has announced its intention to begin the drug registration process in Brazil and Colombia for its over-the-counter pain reliever. The company is currently marketing a similar analgesic, Cobroxin, in the United States for the treatment of moderate to severe (Stage 2) chronic pain. (PRWeb Nov 16, 2009) Read the full story at http://www.prweb.com/releases/Nutra_Pharma/OTC_pain_reliever/prweb3210214.htm (Source: PRWeb: Medical Pharmaceuticals)
Source: PRWeb: Medical Pharmaceuticals - November 16, 2009 Category: Pharmaceuticals Source Type: news

Is chronic pain a disease in its own right?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Review poses the question as to whether chronic pain should be treated as a disease in its own right, rather than as a symptom (Source: Nursing in Practice)
Source: Nursing in Practice - November 16, 2009 Category: Nursing Source Type: news

Depression Patients More Apt To Receive Opioids For Chronic PainEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Chronic pain patients with a history of depression are three times more likely to receive long-term prescriptions for opioid medications like Vicodin compared to pain patients who do not suffer from depression, according to new research. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 16, 2009 Category: Consumer Health News Tags: Depression Source Type: news

Depression Patients More Apt To Receive Opioids For Chronic PainEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Chronic pain patients with a history of depression are three times more likely to receive long-term prescriptions for opioid medications like Vicodin compared to pain patients who do not suffer from depression, according to new research. The study, published in the November-December issue of the journal General Hospital Psychiatry, analyzed the medical records of tens of thousands of patients enrolled in the Kaiser Permanente and Group Health plans between 1997 and 2005. (Source: Pain / Anesthetics News From Medical News Today)
Source: Pain / Anesthetics News From Medical News Today - November 16, 2009 Category: Anesthesiology Tags: Depression Source Type: news

FDA OKs Menstrual Drug LystedaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Title: FDA OKs Menstrual Drug LystedaCategory: Health NewsCreated: 11/16/2009 11:45:00 AMLast Editorial Review: 11/16/2009 11:45:22 AM (Source: MedicineNet Chronic Pain General)
Source: MedicineNet Chronic Pain General - November 16, 2009 Category: Anesthesiology Source Type: consumer

Hip Fracture Odds Rise With Women's AgeEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Title: Hip Fracture Odds Rise With Women's AgeCategory: Health NewsCreated: 11/13/2009 4:10:00 PMLast Editorial Review: 11/16/2009 (Source: MedicineNet Chronic Pain General)
Source: MedicineNet Chronic Pain General - November 16, 2009 Category: Anesthesiology Source Type: consumer

High-Impact Activity May Be Good for Old BonesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Title: High-Impact Activity May Be Good for Old BonesCategory: Health NewsCreated: 11/14/2009 8:10:00 AMLast Editorial Review: 11/16/2009 (Source: MedicineNet Chronic Pain General)
Source: MedicineNet Chronic Pain General - November 16, 2009 Category: Anesthesiology Source Type: consumer

Placebo effect may actually reduce painEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Hamburg - Contrary to conventional thought, the 'placebo effect' may be effective in reducing chronic pain, German researchers (Source: Monsters and Critics Health News)
Source: Monsters and Critics Health News - November 16, 2009 Category: Consumer Health News Source Type: news