Congenital Diaphragmatic Hernia RepairThis is an RSS file. You can use it to subscribe to this data in your favourite RSS reader, such as GoogleReader, or to display this data on your own website or blog. Subscribe to this data using MyMedWorm.Subscribe to this data using GoogleReader.Subscribe to this data using Bloglines.Subscribe to this data using MyYahoo.

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Tracheomegaly: a complication of fetal endoscopic tracheal occlusion in the treatment of congenital diaphragmatic herniaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion There are no previous reports in the literature describing tracheomalacia, or more specifically, tracheomegaly, as a consequence of FETO. We propose that the particularly compliant fetal airway is at risk of mechanical damage from in utero balloon occlusion. This observation of a new problem in this cohort suggests a thorough evaluation of the trachea should be performed in children who have had FETO in utero. It may be that balloon occlusion of the trachea earlier in utero (before 26 weeks’ gestation) predisposes to this condition. Content Type Journal ArticleCategory Original Artic...
Source: Pediatric Radiology - November 5, 2009 Category: Radiology Tags: Pediatric Radiology Source Type: journals

PrefaceEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The integrity and function of the diaphragm is essential to life because of its role in respiration. It is similar to the heart in that the muscle of the diaphragm must contract continuously throughout life. Any breach or dysfunction of the diaphragm may be a threat to life; hence, a thorough knowledge of the anatomy, physiology, and conditions of the diaphragm are essential to the practice of thoracic surgery. Thoracic surgeons must be able to repair or reconstruct the diaphragm when its integrity is breached by congenital abnormalities, acquired hernias, trauma, tumors, or surgical incisions. In acquired conditions that ...
Source: Thoracic Surgery Clinics - November 1, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Gail Darling Source Type: journals

Surgical Conditions of the Diaphragm: Posterior Diaphragmatic Hernias in InfantsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This article reviews the diagnosis and management strategies of congenital diaphragmatic hernia and the outcomes of congenital diaphragmatic hernia patients. (Source: Thoracic Surgery Clinics)
Source: Thoracic Surgery Clinics - November 1, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Priscilla P.L. Chiu, Jacob C. Langer Source Type: journals

Congenital Diaphragmatic Hernia in the AdultEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Congenital diaphragmatic herniae (CDH) are uncommon in neonates and extremely rare in adults. The clinical presentation of CDH in adults tends to be very different from neonates. Many adults remain asymptomatic and CDH are diagnosed incidentally. All CDH should be repaired. Minimally invasive surgical approaches are now gaining popularity for the repair of CDH with excellent outcomes. (Source: Thoracic Surgery Clinics)
Source: Thoracic Surgery Clinics - November 1, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Lana Schumacher, Sebastien Gilbert Source Type: journals

Microscopic magnetic resonance in congenital diaphragmatic hernia and associated malformations in ratsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions Microscopic magnetic resonance involves refined and expensive equipment but it provides a powerful research tool for the study of CDH and other malformations in rat fetuses. Further work on this area is warranted. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00383-009-2518-4Authors Montserrat Bret, Hospital Universitario La Paz Department of Radiology Madrid SpainAna Lourdes Luis, Hospital Universitario La Paz Department of Pediatric Surgery Paseo de la Castellana 261 28046 Madrid SpainEmilio Cuesta, Hospital Universitario La Paz Department of Radiology Madrid SpainFede...
Source: Pediatric Surgery International - October 23, 2009 Category: Surgery Tags: Pediatric surgery International Source Type: journals

Disturbance of parathyroid hormone-related protein signaling in the nitrofen-induced hypoplastic lungEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion Downregulation of PTHrP and PTHrP-R gene expression during late lung morphogenesis may cause pulmonary hypoplasia in the nitrofen CDH model, disrupting alveolar maturation and surfactant production by interfering with mesenchymal–epithelial interactions. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00383-009-2506-8Authors Takashi Doi, Our Lady’s Children’s Hospital The Children’s Research Centre Dublin 12 IrelandAušra Lukošiūtė, Our Lady’s Children’s Hospital The Children’s Research Centre Dublin 12 IrelandElke Ruttenstock, Our Lady’s Children’s Hos...
Source: Pediatric Surgery International - October 23, 2009 Category: Surgery Tags: Pediatric surgery International Source Type: journals

The evidence base for neonatal surgeryEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract: The practise of evidence based medicine means integrating the clinical expertise with the best available external clinical evidence from systematic research. There is a lack of supporting scientific evidence from rigorous trials in neonatal surgery. The indications for surgery and the type of operation performed in neonates are rarely supported by randomised controlled trials. As a consequence, the majority of the operations performed in neonates are supported by retrospective studies and surgeon preference.This review article is focussed on operations in neonates which are performed by general paediatric surgeon...
Source: Early Human Development - October 23, 2009 Category: Perinatology & Neonatology Authors: Nigel J. Hall, Simon Eaton, Agostino Pierro Tags: Guest Editor N. Modi Source Type: journals

Upregulation of Endothelin Receptors A and B in the nitrofen induced hypoplastic lung occurs early in gestationEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion Altered expression of EDNRA and EDNRB is an early event in lung morphogenesis in the nitrofen model. We speculate that pulmonary arteries in CDH become excessively muscularised in early fetal life, becoming unable to adapt normally at birth. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00383-009-2514-8Authors Jens Dingemann, The Children’s Research Centre, Our Lady’s Children’s Hospital Dublin 12 IrelandTakashi Doi, The Children’s Research Centre, Our Lady’s Children’s Hospital Dublin 12 IrelandElke Ruttenstock, The Children’s Research Centre, Our Lady’s ...
Source: Pediatric Surgery International - October 22, 2009 Category: Surgery Tags: Pediatric surgery International Source Type: journals

Downregulation of insulin-like growth factor binding protein 3 and 5 in nitrofen-induced pulmonary hypoplasiaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion Downregulation of IGFBP-3 and IGFBP-5 gene expression may cause pulmonary hypoplasia in the nitrofen-induced CDH model by interfering with retinoid signaling pathway. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00383-009-2509-5Authors Elke Ruttenstock, University College Dublin The Children’s Research Centre, Our Lady’s Children’s Hospital Dublin 12 IrelandTakashi Doi, University College Dublin The Children’s Research Centre, Our Lady’s Children’s Hospital Dublin 12 IrelandJens Dingemann, University College Dublin The Children’s Research Centre, Our Lady�...
Source: Pediatric Surgery International - October 21, 2009 Category: Surgery Tags: Pediatric surgery International Source Type: journals

Does Overnight Birth Influence Treatment or Outcome in Congenital Diaphragmatic Hernia?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We examined the effect of overnight birth on treatment and outcome (including initial cardiorespiratory stabilization) in newborns with congenital diaphragmatic hernia (CDH). CDH births between May 2005 and May 2008 were abstracted from a national CDH database. Overnight birth was defined as occurring between 8 and 8 . Patient characteristics, treatment, and outcomes were compared between birth time groups, including the subset of infants in whom a prenatal diagnosis of CDH had been made. Of 132 cases evaluated, 106 (80%) survived. Forty-nine babies (37%) were born overnight. Eighty-five infants (64%) with a prenatal diagn...
Source: American Journal of Perinatology - October 13, 2009 Category: Perinatology & Neonatology Source Type: journals

Prenatal retinoic acid up-regulates pulmonary gene expression of COUP-TFII, FOG2, and GATA4 in pulmonary hypoplasiaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Up-regulation of pulmonary gene expression of COUP-TFII, FOG2, and GATA4 after prenatal treatment with retinoic acid in the nitrofen model of CDH suggests that RA may have a therapeutic potential in modulating lung growth. Furthermore, these results support the concept that these proteins work together to regulate downstream target genes that play an important role in the development of lung. (Source: Journal of Pediatric Surgery)
Source: Journal of Pediatric Surgery - September 30, 2009 Category: Surgery Authors: Takashi Doi, Kaoru Sugimoto, Prem Puri Tags: Original Articles Source Type: journals

Congenital diaphragmatic hernia: outcome review of 2,173 surgical repairs in US infantsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This study, which represents the largest characterization of US infants who have undergone CDH repair using data from a nationally representative non-voluntary database, demonstrates that surgical repair is associated with significant mortality and morbidity. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00383-009-2473-0Authors Fizan Abdullah, Johns Hopkins University School of Medicine Division of Pediatric Surgery, Center for Pediatric Surgical Clinical Trials and Outcomes Research 600 North Wolfe Street, Harvey 319 Baltimore MD 21287-0005 USAYiyi Zhang, Johns Hopkins University Bloomberg Schoo...
Source: Pediatric Surgery International - September 3, 2009 Category: Surgery Tags: Pediatric surgery International Source Type: journals

Congenital diaphragmatic hernia: neonatal outcomes following referral to a paediatric surgical centre.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Congenital diaphragmatic hernia (CDH) is a rare malformation observed in approximately 1 in 3000 live births. Estimates of postnatal survival range from 50 to 70% despite advances in neonatal care. Antenatal diagnosis is associated with termination of pregnancy in 25-50% pregnancy internationally which may not be reflective of the Irish population. We aimed to evaluate the mortality of infants with CDH who survived to admission in a tertiary referral paediatric hospital between 1996 and 2007. The Hospital In-Patient Enquiry system was used to determine the number of neonatal referrals for CDH to OLHSC between 1996 and ...
Source: Ir Med J - September 1, 2009 Category: Journals (General) Authors: Chukwu J, Iro C, Donoghue V, McCallion N, Murphy JF, Quinn F, Healy M, Molloy EJ Tags: Ir Med J Source Type: journals

A prospective comparative evaluation of persistent respiratory morbidity in esophageal atresia and congenital diaphragmatic hernia survivorsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Esophageal atresia and CDH are associated with equal risk of long-term respiratory morbidity, growth impairment, and disturbed maximal exercise performance. Prospective follow-up of EA patients aimed at identifying respiratory problems other than tracheomalacia should be an integral part of interdisciplinary follow-up programs. (Source: Journal of Pediatric Surgery)
Source: Journal of Pediatric Surgery - August 31, 2009 Category: Surgery Authors: Saskia J. Gischler, Monique H.M. van der Cammen-van Zijp, Petra Mazer, Gerard C. Madern, Nikolaas M.A. Bax, Johan C. de Jongste, Monique van Dijk, Dick Tibboel, Hanneke Ijsselstijn Tags: Original Articles Source Type: journals

Outcome analysis of neonates with congenital diaphragmatic hernia treated with venovenous vs venoarterial extracorporeal membrane oxygenationEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: The short-term outcomes of VV and VA are comparable. Patients with CDH who fail VV may be predisposed to a worse outcome. Nevertheless, VV offers equal benefit to patients with CDH requiring ECMO while preserving the native carotid. (Source: Journal of Pediatric Surgery)
Source: Journal of Pediatric Surgery - August 31, 2009 Category: Surgery Authors: Yigit S. Guner, Robinder G. Khemani, Faisal G. Qureshi, Choo Phei Wee, Mary T. Austin, Fred Dorey, Peter T. Rycus, Henri R. Ford, Philippe Friedlich, James E. Stein Tags: Original Articles Source Type: journals

Beyond feasibility: a comparison of newborns undergoing thoracoscopic and open repair of congenital diaphragmatic herniasEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Successful thoracoscopic CDH repair can be expected in newborns, which has limited respiratory compromise. Thoracoscopic CDH repair is associated with lower morbidity and quicker recovery than traditional open repair and without increased risk of recurrence or complications. (Source: Journal of Pediatric Surgery)
Source: Journal of Pediatric Surgery - August 31, 2009 Category: Surgery Authors: David M. Gourlay, Laura D. Cassidy, Thomas T. Sato, Dave R. Lal, Marjorie J. Arca Tags: Original Articles Source Type: journals

Thoracic kidney associated with congenital diaphragmatic herniaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report three cases of ectopic thoracic (or superior ectopic) kidney; one in a neonate and two in 6-month-old children, associated with congenital diaphragmatic hernia. In all cases the diagnosis was made during surgery and confirmed by intravenous pyelography, sonography and magnetic resonance imaging in the postoperative period. Because of the rarity of this condition we report these cases together with a wide review of the published reports. (Source: Congenital Anomalies)
Source: Congenital Anomalies - August 25, 2009 Category: Genetics & Stem Cells Authors: Kamal N. Rattan, Seema Rohilla, Rajat Narang, Simmi K. Rattan, Sarita Maggu, Dhara B. Dhaulakhandi Tags: Case Reports Source Type: journals

Pneumomediastinum and Tension Pneumopericardium After Congenital Diaphragmatic Hernia Repair: Presentation and Transcatheter DrainageEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Content Type Journal ArticleCategory Images in Pediatric CardiologyDOI 10.1007/s00246-009-9519-xAuthors James S. Killinger, Children’s Hospital at Montefiore, Montefiore Medical Center and Albert Einstein College of Medicine Department of Pediatrics 3415 Bainbridge Avenue, Rosenthal 1 Bronx NY 10467-2183 USASara L. P. Ross, Children’s Hospital at Montefiore, Montefiore Medical Center and Albert Einstein College of Medicine Department of Pediatrics 3415 Bainbridge Avenue, Rosenthal 1 Bronx NY 10467-2183 USARobert H. Pass, Children’s Hospital at Montefiore, Montefiore Medical Center and Albert Einstein College of M...
Source: Pediatric Cardiology - August 25, 2009 Category: Cardiology Tags: Pediatric Cardiology Source Type: journals

Sonic hedgehog gene expression in nitrofen induced hypoplastic lungs in miceEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion Although altered Shh expression in the hypoplastic lung has been reported in late gestation, the present study did not reveal any significant alterations in pulmonary Shh spatial transcript distribution or gene expression level during the early gestation in nitrofen CDH model. It would be of great interest in future studies to use OPT approach to investigate pulmonary expression of Shh and other regulatory genes both during early and late stages of lung development in order to provide new insights into the pathogenesis of pulmonary hypoplasia. Content Type Journal ArticleCategory Original A...
Source: Pediatric Surgery International - August 19, 2009 Category: Surgery Tags: Pediatric surgery International Source Type: journals

What Are the Complications of Cardiothoracic Surgery?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Discussion Congenital diaphragmatic hernia (CDH) occurs in 1 / 2000-3000 live births. Its overall mortality has been hard to determine as many infants die in-utero or just after birth before transfer for surgical care. One study found that ~61% of fetuses with CDH are live born. Many of these fetuses had other congenital anomalies. Mortality after live birth is ~ 40-62%. There are 3 major types of CDH: Bochdalek hernia which occurs posterolaterally Morgagni hernia which occurs anteriorly Hiatus hernia Left sided Bochdalek hernias are the most common (85%). Treatment currently includes fetal surgical repair, post-natal ...
Source: PediatricEducation.org - August 17, 2009 Category: Pediatrics Authors: Donna M. D'Alessandro, M.D. Tags: Uncategorized Source Type: info

Can we improve outcome of congenital diaphragmatic hernia?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract This review gives an overview of the disease spectrum of congenital diaphragmatic hernia (CDH). Etiological factors, prenatal predictors of survival, new treatment strategies and long-term morbidity are described. Early recognition of problems and improvement of treatment strategies in CDH patients may increase survival and prevent secondary morbidity. Multidisciplinary healthcare is necessary to improve healthcare for CDH patients. Absence of international therapy guidelines, lack of evidence of many therapeutic modalities and the relative low number of CDH patients calls for cooperation between ce...
Source: Pediatric Surgery International - August 9, 2009 Category: Surgery Tags: Pediatric surgery International Source Type: journals

Expression of chloride channels in trachea-occluded hyperplastic lungs and nitrofen-induced hypoplastic lungs in ratsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion We show that the developmental changes in ClC-2 and ClC-3 protein expression are negatively affected in hypoplastic CDH lungs. Lung hyperplasia created by TO up-regulates the expression of ClC-2. ClC-2 is therefore an interesting potential target in the development of novel, non-invasive, therapies for CDH treatment. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00383-009-2423-xAuthors Andreas Ringman Uggla, Karolinska Institutet Research Laboratory Q2:09, Department of Woman and Child Health, Nordic Centre of Excellence for Research in Water Imbalance Related Disorders ...
Source: Pediatric Surgery International - August 3, 2009 Category: Surgery Tags: Pediatric surgery International Source Type: journals

Delayed presentation of congenital diaphragmatic hernia with intrathoracic gastric volvulus.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: GV is a clinical emergency which can be life-threatening for children. Upper gastrointestinal study and CT scan with contrast meal are helpful in the diagnosis of the lesion. We emphasize prompt surgical therapy to avoid gastric necrosis. PMID: 19693469 [PubMed - as supplied by publisher] (Source: World Journal of Pediatrics : WJP)
Source: World Journal of Pediatrics : WJP - July 31, 2009 Category: Pediatrics Authors: Karabulut R, Türkyılmaz Z, Sönmez K, Karakus SC, Basaklar AC Tags: World J Pediatr Source Type: journals

Effect of prenatal tetrandrine administration on transforming growth factor-β1 level in the lung of nitrofen-induced congenital diaphragmatic hernia rat modelEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: Nitrofen can interfere with lung development early in the fetal rat development before and separate from diaphragm development, and increased expression of TGF-β1 in the lung of CDH rat model may suppress lung growth and development. Prenatal treatment with Tet can improve the growth of the lung of the nitrofen-induced CDH fetuses and its mechanism seems to be involved in downregulating the expression of TGF-β1. It is a likely new approach to treat CDH and its coexistent lung hypoplasia by maternal Tet administration. (Source: Journal of Pediatric Surgery)
Source: Journal of Pediatric Surgery - July 28, 2009 Category: Surgery Authors: Chang Xu, Wenying Liu, Zhongxian Chen, Yuanxiang Wang, Zhongxun Xiong, Yi Ji Tags: Original Articles Source Type: journals

Congenital diaphragmatic hernia with a pure duplication of chromosome 1q: report of the first surviving caseEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We present the first surviving case of CDH with a duplication of 1q12–q23, who had arthrogryposis multiplex congenita and hypertrophic cardiomyopathy. CDH patients with a proximal duplication of chromosome 1q may have a chance for survival, and CDH with a duplication of chromosome 1q is not necessarily a lethal association. Content Type Journal ArticleCategory Case ReportDOI 10.1007/s00383-009-2421-zAuthors Kohei Otake, Mie University Graduate School of Medicine Department of Gastrointestinal and Pediatric Surgery Edobashi 2-174 Tsu Mie 514-8507 JapanKeiichi Uchida, Mie University Graduate School of Medicine Depa...
Source: Pediatric Surgery International - July 25, 2009 Category: Surgery Tags: Pediatric surgery International Source Type: journals

Congenital diaphragmatic hernia: review of the literature in reflection of unresolved dilemmasEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: The high survival of 'selected cases' that are live births and benefit from optimal care will be difficult to improve by antenatal interventions. The multidisciplinary approach to basic research and randomized clinical trials will further define the best approach to the foetus and neonate with CDH. (Source: Acta Paediatrica)
Source: Acta Paediatrica - July 19, 2009 Category: Pediatrics Authors: S Grisaru-Granovsky, R Rabinowitz, A Ioscovich, D Elstein, MS Schimmel Source Type: journals

Thoracoscopic Repair of Congenital Diaphragmatic Hernia in Neonates: Lessons LearnedEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Journal of Laparoendoscopic & Advanced Surgical Techniques , Vol. 0, No. 0. (Source: Journal of Laparoendoscopic)
Source: Journal of Laparoendoscopic - July 12, 2009 Category: Surgery Tags: article Source Type: journals

Decreased surfactant phosphatidylcholine synthesis in neonates with congenital diaphragmatic hernia during extracorporeal membrane oxygenationEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion These results show that CDH patients who require ECMO have a decreased surfactant PC synthesis, which may be part of the pathogenesis of severe pulmonary insufficiency and has a negative impact on weaning from ECMO. Content Type Journal ArticleCategory Pediatric OriginalDOI 10.1007/s00134-009-1564-7Authors Daphne J. Janssen, Intensive Care Erasmus MC-Sophia Children’s Hospital Department of Pediatrics and Pediatric Surgery P.O. Box 2060 3000 CB Rotterdam The NetherlandsLuc J. Zimmermann, University Hospital Maastricht Division of Neonatology Maastricht The NetherlandsPaola Cogo, University...
Source: Intensive Care Medicine - July 7, 2009 Category: Intensive Care Tags: Intensive Care Medicine Source Type: journals

Anterior fundoplication at the time of congenital diaphragmatic hernia repairEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion Anatomic predictors of severe GER can be efficiently countered at the time of CDH repair. A modified fundoplication should be considered in the operative management of high-risk infants. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00383-009-2411-1Authors Yigit S. Guner, University of California Davis Medical Center Department of General Surgery Sacramento CA 95817 USASteven Elliott, University of California Davis Medical Center Department of General Surgery Sacramento CA 95817 USAClifford C. Marr, University of California Davis Medical Center Department of General Surge...
Source: Pediatric Surgery International - July 6, 2009 Category: Surgery Tags: Pediatric surgery International Source Type: journals

Prenatal findings of concomitant duodenal and esophageal atresia without tracheoesophageal fistula (Gross type A)Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We describe prenatal findings of one such case. Sonographic examination of a 26-week fetus showed a double cystic structure and an intrathoracic cyst. MRI and ultrasound at 26 weeks and 2 days' gestation showed shrinkage of the stomach and duodenum, massive ascites, and the presence of dilated pouch-like structure in the thoracic inlet level, consistent with an upper pouch sign. Polyhydramnios was detected at 30 weeks' gestation. Prenatal diagnosis was concomitant DA and an intrathoracic anomaly such as congenital hiatal hernia, diaphragmatic hernia, esophageal duplication or EA. A boy was delivered at 38 weeks' gestation....
Source: Journal of Clinical Ultrasound - July 4, 2009 Category: Radiology Authors: Yasuyuki Mitani, Toshimichi Hasegawa, Akio Kubota, Hisayoshi Kawahara, Akihiro Yoneda, Keisuke Nose, Motonari Nomura Source Type: journals

Impaired somatic growth and delayed lung development in infants with congenital diaphragmatic hernia—evidence from a 10-year, single center prospective follow-up studyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: Despite apparently well-inflated lungs after surgery, evidence of early and significantly reduced weight gain and impaired lung function in CHD patients should prompt careful dietary monitoring and regular lung function testing. (Source: Journal of Pediatric Surgery)
Source: Journal of Pediatric Surgery - June 30, 2009 Category: Surgery Authors: Charles Christoph Roehr, Hans Proquitté, Andreas Jung, Ulrike Ackert, Christian Bamberg, Petra Degenhardt, Hannes Hammer, Roland R. Wauer, Gerd Schmalisch Tags: Original Articles Source Type: journals

Factors associated with survival in infants with congenital diaphragmatic hernia requiring extracorporeal membrane oxygenation: a report from the Congenital Diaphragmatic Hernia Study GroupEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: Our model identifies a group of pre-surgical and postsurgical parameters that predict survival rate in patients with CDH on ECMO support. This model was derived from the retrospective data from a large database and will need to be prospectively tested. (Source: Journal of Pediatric Surgery)
Source: Journal of Pediatric Surgery - June 30, 2009 Category: Surgery Authors: Rupa Seetharamaiah, John G. Younger, Robert H. Bartlett, Ronald B. Hirschl, On behalf of the congenital diaphragmatic hernia Study Group Tags: Original Articles Source Type: journals

Interdisciplinary structural follow-up of surgical newborns: a prospective evaluationEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: The CA survivors show impaired growth and psychomotor developmental delay up to age 2 years. This warrants specific follow-up programs and infrastructure for these patients. (Source: Journal of Pediatric Surgery)
Source: Journal of Pediatric Surgery - June 30, 2009 Category: Surgery Authors: Saskia J. Gischler, Petra Mazer, Hugo J. Duivenvoorden, Monique van Dijk, Nikolaas M.A. Bax, Frans W.J. Hazebroek, Dick Tibboel Tags: Original Articles Source Type: journals

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Prostaglandin-E1 (PGE1) is used at most centers for treating pulmonary hypertension (PH) in congenital diaphragmatic hernia (CDH) because it has been regarded as effective. The aim of this study was to investigate the role of PGE1 for treating PH in CDH. Forty-nine CDH cases were reviewed with echocardiography-proven PH. PH was treated with PGE1 and nitric oxide (NO) and high-frequency oscillatory ventilation (HFOV) from 1997 to 2001 (PG + NO; n = 19) and with NO and HFOV from 2002 to 2007 (NO; n = 30). Subject demographics, severity of PH, and presence of other anomalies were not significantly different between the 2 grou...
Source: Journal of Pediatric Surgery - June 30, 2009 Category: Surgery Authors: Federico G Seifarth Tags: Special Department Source Type: journals

Wandering Spleen Causing Intestinal Obstruction after Repair of Congenital Diaphragmatic HerniaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Eur J Pediatr SurgDOI: 10.1055/s-0029-1220708© Georg Thieme Verlag KG Stuttgart · New YorkGet connected:Table of contents | Full text (Source: European Journal of Pediatric Surgery)
Source: European Journal of Pediatric Surgery - June 25, 2009 Category: Surgery Tags: Case Gallery Source Type: journals

The impact of iatrogenic gastroschisis on pulmonary maturation in the fetal rabbit models of congenital diaphragmatic herniaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions In the fetal rabbit models of CDH, pulmonary hypoplasia is the most significant pathological feature. Iatrogenic gastroschisis does not improve pulmonary maturation due to the active growth of the liver that herniates into the thoracic cavity. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00383-009-2384-0Authors Gong Chen, FUDAN University Shanghai ChinaShan Zheng, FUDAN University Shanghai ChinaXian Min Xiao, FUDAN University Shanghai ChinaYi Luo, FUDAN University Shanghai China Journal Pediatric Surgery InternationalOnline ISSN 1437-9813Print ISSN 0179-0358 (Sou...
Source: Pediatric Surgery International - June 13, 2009 Category: Surgery Tags: Pediatric surgery International Source Type: journals

The Myenteric Plexus of the Esophagus is Abnormal in an Experimental Congenital Diaphragmatic Hernia ModelEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Eur J Pediatr Surg 2009; 19: 163-167DOI: 10.1055/s-0029-1202854Abstract Infants surviving congenital diaphragmatic hernia (CDH) suffer from anatomical and functional esophageal abnormalities. Previous work in the nitrofen animal model of CDH demonstrated malformations in neural crest-derived structures, including the vagus and recurrent laryngeal nerves. The aim of the present study was to assess whether the esophageal myenteric plexus is abnormal in rats with CDH.[...]© Georg Thieme Verlag KG Stuttgart · New YorkGet connected:Table of contents | Abstract | Full text (Source: European Journal of Pediatric Surgery)
Source: European Journal of Pediatric Surgery - June 8, 2009 Category: Surgery Tags: Original Article Source Type: journals

Tracheal innervation is abnormal in rats with experimental congenital diaphragmatic herniaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Decreased density of neural structures and size of intramural ganglia, reduced expression of neural tissue and PGP 9.5 protein, and increased levels of PGP 9.5 mRNA reveal deficient tracheal innervation in rats with CDH. If similar anomalies exist in the human condition, they could contribute to explaining the pathogenesis of lung hypoplasia and bronchopulmonary sequelae. (Source: Journal of Pediatric Surgery)
Source: Journal of Pediatric Surgery - May 31, 2009 Category: Surgery Authors: Federica Pederiva, Rosa Aras Lopez, Leopoldo Martinez, Juan A. Tovar Tags: AAP Papers Source Type: journals

Congenital diaphragmatic hernia requiring extracorporeal membrane oxygenation: does timing of repair matter?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: These data suggest that CDH repair after ECMO therapy is associated with improved survival compared to repair on ECMO, despite controlling for factors associated with the severity of CDH. (Source: Journal of Pediatric Surgery)
Source: Journal of Pediatric Surgery - May 31, 2009 Category: Surgery Authors: Benjamin S. Bryner, Brady T. West, Ronald B. Hirschl, Robert A. Drongowski, Kevin P. Lally, Pamela Lally, George B. Mychaliska, The congenital diaphragmatic hernia Study Group Tags: AAP Papers Source Type: journals

Multivariate model for predicting recurrence in congenital diaphragmatic herniaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: Neonates at risk for CDH recurrence are better identified by postnatal treatment variables than by prenatal patient factors. Although age at repair and diaphragm patch use are greater in recurrence patients, the only factors to independently predict recurrence were postoperative LOS and abdominal wall patch use. These data can help optimize follow-up regimens. (Source: Journal of Pediatric Surgery)
Source: Journal of Pediatric Surgery - May 31, 2009 Category: Surgery Authors: Jason C. Fisher, Mary Jo Haley, Alejandro Ruiz-Elizalde, Charles J.H. Stolar, Marc S. Arkovitz Tags: AAP Papers Source Type: journals

Chylothorax after congenital diaphragmatic hernia repairEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: The incidence of chylothorax at our institution was relatively low. Patch repair was associated with the formation of chylothorax. Morbidity was substantial, but survival was not significantly affected. Total parenteral nutrition and thoracostomy were appropriate initial treatments. Octreotide was not an effective adjunct. Refractory cases were successfully treated with pleurectomy. (Source: Journal of Pediatric Surgery)
Source: Journal of Pediatric Surgery - May 31, 2009 Category: Surgery Authors: Raquel Gonzalez, Benjamin S. Bryner, Daniel H. Teitelbaum, Ronald B. Hirschl, Robert A. Drongowski, George B. Mychaliska Tags: AAP Papers Source Type: journals

Influence of extracorporeal membrane oxygenation on subsequent surgeries after congenital diaphragmatic hernia repairEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: In this series, ECMO survivors are at a high risk for requiring subsequent surgeries compared to the total CDH group. This information can be used as an education tool for referring physicians and parents as they care for this group of children. (Source: Journal of Pediatric Surgery)
Source: Journal of Pediatric Surgery - May 31, 2009 Category: Surgery Authors: Francine D. Breckler, Kimberly A. Molik, Karen W. West Tags: AAP Papers Source Type: journals

Persistent nonhealing skin fistulous tract after congenital diaphragmatic hernia repair.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19503656 [PubMed - indexed for MEDLINE] (Source: Canadian Journal of Surgery)
Source: Canadian Journal of Surgery - May 31, 2009 Category: Surgery Authors: Vasquez JC, Montesinos E, DeLaRosa J, Leon JJ Tags: Can J Surg Source Type: journals

Thoracoscopic Repair in the Neonatal Intensive Care Unit for Congenital Diaphragmatic Hernia During High-Frequency Oscillatory VentilationEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Journal of Laparoendoscopic & Advanced Surgical Techniques , Vol. 0, No. 0. (Source: Journal of Laparoendoscopic)
Source: Journal of Laparoendoscopic - May 11, 2009 Category: Surgery Tags: article Source Type: journals

Improvement in the outcome of patients with antenatally diagnosed congenital diaphragmatic hernia using gentle ventilation and circulatory stabilizationEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion Our strategy of using GV ± CS might thus be considered to be more effective than that using FS in the treatment of AD-CDH patients. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00383-009-2370-6Authors Kouji Masumoto, Graduate School of Medical Sciences, Kyushu University Department of Pediatric Surgery, Reproductive and Developmental Medicine 3-1-1, Maidashi, Higashi-ku Fukuoka 812-8582 JapanRisa Teshiba, Graduate School of Medical Sciences, Kyushu University Department of Pediatric Surgery, Reproductive and Developmental Medicine 3-1-1, Maidashi, Higashi-ku F...
Source: Pediatric Surgery International - May 7, 2009 Category: Surgery Tags: Pediatric surgery International Source Type: journals

Caecal perforation with faecal peritonitis - unusual presentation of Bochdalek hernia in an adult: a case report and review of literatureEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The improper fusion of the postero-lateral foramen of the diaphragm was first described by Bochdalek in 1848. The incidence of congenital diaphragmatic hernia varies from1:2000 to 1:5000 live births and Bochdalek hernias (BH) account for 75 to 85 % of these. Although it is a well-known entity in neonates, it is occasionally discovered incidentally in adult patients. Until now, a total of around 100 cases of occult asymptomatic Bochdalek hernia have been reported. The symptomatic cases are encountered more rarely. Colon necrosis among the symptomatic cases was reported in some reports. We discuss the present case since we b...
Source: World Journal of Emergency Surgery - May 6, 2009 Category: Emergency Medicine Authors: Ameet Kumar, Vikas Maheshwari, T. s. Ramakrishnan and Samaresh Sahu Source Type: journals

Effect of hospital case volume on outcome in congenital diaphragmatic hernia: the experience of the Canadian Pediatric Surgery NetworkEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: Hospital case volume may be partially responsible for mortality rate variation in CDH. This result requires careful analysis, as case volume may merely be a surrogate for other predictive variables. (Source: Journal of Pediatric Surgery)
Source: Journal of Pediatric Surgery - May 1, 2009 Category: Surgery Authors: Jeremy R. Grushka, Jean-Martin Laberge, Pramod Puligandla, Erik D. Skarsgard, the Canadian Pediatric surgery Network Tags: Caps Original Papers Source Type: journals

Absolute vs relative improvements in congenital diaphragmatic hernia survival: what happened to “hidden mortality”Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: A hidden mortality exists for institutionally reported CDH survival rates. Careful interpretation of research findings and more comprehensive population-based tools are needed for reliable counseling and evaluation of current and future treatments. (Source: Journal of Pediatric Surgery)
Source: Journal of Pediatric Surgery - May 1, 2009 Category: Surgery Authors: V. Kandice Mah, Mohammed Zamakhshary, Doug Y. Mah, Brian Cameron, Juan Bass, Desmond Bohn, Leslie Scott, Sharifa Himidan, Mark Walker, Peter C.W. Kim Tags: Caps Original Papers Source Type: journals

Right-sided congenital diaphragmatic hernia: high utilization of extracorporeal membrane oxygenation and high survivalEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Our data suggest that patients with R-CDH have high ECMO utilization and may experience greater relative benefit from ECMO as evidenced by their higher-than-expected overall survival. Extracorporeal membrane oxygenation may be found to have a distinctive role in managing R-CDH. More high-powered series are needed to elucidate differences between R-CDH and left-sided CDH that may dictate alternate forms of management. (Source: Journal of Pediatric Surgery)
Source: Journal of Pediatric Surgery - May 1, 2009 Category: Surgery Authors: Benjamin S. Bryner, Anne C. Kim, Joseph S. Khouri, Robert A. Drongowski, Steven W. Bruch, Ronald B. Hirschl, George B. Mychaliska Tags: Caps Original Papers Source Type: journals

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The aim of this study was to describe the long-term functional impact of congenital diaphragmatic hernia (CDH) repair on survivors of a cohort of newborns. The medical charts of 26 CDH survivors were analyzed. The median age at follow-up was 51 (14-141) months. One patient (4%) had died by the age of 3 months. Thirteen patients (50%) presented with at least one sequelae, 6 (23%) presented with 2 or more. Gastrointestinal problems were the most prevalent, with 6 children (23%) below the fifth percentile for weight and 3 (12%) with gastroesophageal reflux. Respiratory morbidity was present in 4 patients (15%). Four (15%) exh...
Source: Journal of Pediatric Surgery - May 1, 2009 Category: Surgery Authors: Thomas A. Angerpointner Tags: Special Department Source Type: journals