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This page shows you the latest news and research items in this category.

Long-term Outcomes after Frey's Procedure for Chronic Pancreatitis with an Inflammatory Mass of the Pancreatic Head, with Special Reference to Locoregional Complications.
Conclusion: Frey's procedure is safe and effective with regard to pain relief, preservation of pancreatic function, and improvement of QOL over the long term. Moreover, this procedure can also be used to treat preoperative biliary stricture and duodenal stenosis associated with an inflammatory mass of the pancreatic head. PMID: 23657068 [PubMed - in process] (Source: Journal of Nippon Medical School)
Source: Journal of Nippon Medical School - May 26, 2013 Category: Universities & Medical Training Authors: Aimoto T, Uchida E, Matsushita A, Kawano Y, Mizutani S, Kobayashi T Tags: J Nippon Med Sch Source Type: research

Adenocarcinoma of the minor duodenal papilla: report of a case.
We report a rare case of adenocarcinoma of the minor papilla of the duodenum treated with transduodenal minor papillectomy. A 64-year-old woman was treated for an asymptomatic duodenal tumor detected on gastroduodenoscopy. Endoscopy showed a 15-mm sessile mass in the descending duodenum proximal to the major papilla. The major papilla was a villous 24-mm-diameter polypoid tumor. Histopathologic examination of the biopsy specimen showed tubular adenoma with moderate epithelial atypia. Transduodenal major and minor papillectomies were performed. The orifice of the duct of Santorini and the pancreatic duct were re-approximate...
Source: Journal of Nippon Medical School - May 26, 2013 Category: Universities & Medical Training Authors: Hoshino A, Nakamura Y, Suzuki H, Mizutani S, Ishii H, Watanabe M, Bou H, Yoshino M, Komine O, Uchida E Tags: J Nippon Med Sch Source Type: research

Acute Onset Vomiting in a Toddler: An Uncommon Presentation of Duodenal Stenosis
(Source: Clinical Pediatrics)
Source: Clinical Pediatrics - May 8, 2013 Category: Pediatrics Authors: Solomon, A. B., Sockolow, R. E. Tags: Brief Reports Source Type: research

The characterisation and risk factors of ischaemic heart disease in patients with coeliac disease
ConclusionDespite evidence of an increased risk of IHD and higher cardiovascular mortality, patients with coeliac disease with IHD have a more favourable cardiac risk profile compared with IHD in reference individuals. (Source: Alimentary Pharmacology and Therapeutics)
Source: Alimentary Pharmacology and Therapeutics - March 4, 2013 Category: Drugs & Pharmacology Authors: L. Emilsson, R. Carlsson, M. Holmqvist, S. James, J. F. Ludvigsson Tags: Original Article Source Type: research

A Novel Mutation in FOXF1 Gene Associated with Alveolar Capillary Dysplasia with Misalignment of Pulmonary Veins, Intestinal Malrotation and Annular Pancreas.
Abstract Alveolar capillary dysplasia with misalignment of pulmonary veins (ACD/MPV) is a rare, fatal, neonatal developmental lung disorder, which usually presents as persistent pulmonary hypertension unresponsive to treatment. The authors report the case of a neonate with persistent pulmonary hypertension, associated with duodenal stenosis secondary to annular pancreas and intestinal malrotation. Support treatment, inhaled nitric oxide, oral sildenafil and nebulized iloprost were used with no clinical improvement. The neonate presented an overwhelming course, with hypoxemia refractory to treatment. At autopsy lung...
Source: Neonatology - February 12, 2013 Category: Perinatology & Neonatology Authors: Miranda J, Rocha G, Soares P, Morgado H, Baptista MJ, Azevedo I, Fernandes S, Brandão O, Sen P, Guimarães H Tags: Neonatology Source Type: research

Dietary Glycemic Index and the Risk of Birth Defects
Prepregnancy diabetes and obesity have been identified as independent risk factors for several birth defects, providing support for a mechanism that involves hyperglycemia and hyperinsulinemia in the development of malformations. Data from the National Birth Defects Prevention Study from 1997 to 2007 were used to investigate the association between the maternal dietary glycemic index (DGI) and the risk of birth defects among nondiabetic women. DGI was categorized by using spline regression models and quartile distributions. Adjusted odds ratios and 95% confidence intervals were calculated. The joint effect of DGI and obesi...
Source: American Journal of Epidemiology - December 13, 2012 Category: Epidemiology Authors: Parker, S. E., Werler, M. M., Shaw, G. M., Anderka, M., Yazdy, M. M., the National Birth Defects Prevention Study Tags: RESEARCH-ARTICLE Source Type: research

Multiple pancreaticoduodenal artery aneurysms with a primary duodenal fistula
A 48-year-old woman presented with hematemesis and melena. She was a nonsmoker, with a history of hypercholesterolemia. There was no history of alcohol abuse or pancreatitis. She was investigated with a gastroscopy, capsule endoscopy, and push enteroscopy, all of which failed to demonstrate a source of bleeding. She had an episode of syncope associated with a drop in hemoglobin to 47g/L. A computed tomography angiogram demonstrated two saccular aneurysms arising from the inferior pancreaticoduodenal artery measuring 2.5 × 1.9 cm and 2.0 × 2.6 cm, with the larger aneurysm closely abutting the third part of the duodenum. A...
Source: Journal of Vascular Surgery - November 26, 2012 Category: Surgery Authors: Domenic R. Robinson, Peter S. Subramaniam, Martin Bruening, Glen L. Benveniste Tags: Vascular images Source Type: research

A rare microduplication in a familial case of annular pancreas and duodenal stenosis
Conclusions: The 6q24.2 mircoduplication of the utrophin gene is a potential risk factor for the development of annular pancreas, but further studies will clarify the exact role and if this is a true risk factor or a rare normal variant. (Source: Journal of Pediatric Surgery)
Source: Journal of Pediatric Surgery - November 1, 2012 Category: Surgery Authors: Ellen Markljung, Tatjana Adamovic, Lisa Örtqvist, Tomas Wester, Agneta Nordenskjöld Tags: Original Articles Source Type: research

WallFlex™ Duodenal Stent Placement in a Gastric Cancer Patient with Malignant Stenosis of a Roux-en-Y Gastrojejunostomy following Distal Gastrectomy
Case Rep Oncol 2012;5:554–560 (DOI:10.1159/000341851) (Source: Karger Publishers)
Source: Karger Publishers - October 15, 2012 Category: Cancer & Oncology Source Type: research

Celiac disease presenting as recurrent pancreatitis and pseudocyst.
CONCLUSION: This report highlights that celiac disease should be considered in the etiological work up of patients with unexplained pancreatitis. PMID: 22964961 [PubMed - in process] (Source: JOP)
Source: JOP - September 19, 2012 Category: Gastroenterology Authors: Basha J, Appasani S, Vaiphei K, Singh K, Kochhar R Tags: JOP Source Type: research

Plexiform schwannoma of the duodenum accompanying pyloric stenosis: Report of a case.
We describe the first known case of plexiform schwannoma of the duodenum. A 60-year-old man presented with a short history of food intolerance, epigastric discomfort, fullness and bloatedness, sometimes vomiting, and weight loss, without any clinical picture of neurofibromatosis. Upper gastrointestinal endoscopy revealed pyloric stenosis with normal mucosal lining. The computed tomography demonstrated circumferentially and concentrically thickened pylorus up to 18 mm with narrowed lumen and limited contrast passage. Antrectomy and gastrojejunostomy were performed due to unknown etiology of the obstruction. The cut surface ...
Source: The Turkish Journal of Gastroenterology - August 1, 2012 Category: Gastroenterology Authors: Aktekın A, Ozkara S, Merıç K, Günay Gürleyık M, Aker F, Sağlam A Tags: Turk J Gastroenterol Source Type: research

HIV-related/AIDS cholangiopathy: pictorial review with emphasis on MRCP findings and differential diagnosis
Abstract: Magnetic resonance cholangiopancreatography provides accurate, noninvasive diagnosis of HIV/AIDS cholangiopathy through the identification of characteristic ductal abnormalities including multiple intrahepatic strictures, papillary stenosis, and long segmental extrahepatic strictures. Endoscopic retrograde cholangiopancreatography should be reserved for cytological or bioptic investigation in doubtful cases and for operative treatment when appropriate. Furthermore, cross-sectional imaging allows differentiation from other causes of biliary dilatation in HIV-positive patients, including infectious (bacterial) chol...
Source: Clinical Imaging - May 24, 2012 Category: Radiology Authors: Massimo Tonolini, Roberto Bianco Tags: Review Articles Source Type: research

[Post-traumatic small-bowel obstruction: Two case studies.]
Abstract Post-traumatic small-bowel obstructions are rare and late complications following blunt abdominal trauma. Timely diagnosis is frequently impeded because of nonspecific associated symptoms, and furthermore, the degree of urgency is frequently underestimated due to the accidental cause. During the last 6years (2005-2011), we have observed only 2cases (4 and 10years old) with post-traumatic small-bowel obstruction. On admission the patients had a contusion on the abdominal wall, duodenal hematoma and a Chance fracture of the lumbar spine on the computed tomography (CT) scan. Although early clinical improvemen...
Source: Archives de Pediatrie - March 28, 2012 Category: Pediatrics Authors: Faure A, Maurin C, Lauron J, Jouve JL, De Lagausie P, Merrot T Tags: Arch Pediatr Source Type: research

Endoscopic treatment of congenital duodenal membrane
Congenital duodenal membrane is an anomaly characterized by luminal GI obstruction and consists of a diaphragm with multiple central or peripheral openings. The clinical presentation depends on the size of the fenestrations of the diaphragm. In cases of severe stenosis, vomiting and abdominal distention are the presenting symptons. (Source: Gastrointestinal Endoscopy)
Source: Gastrointestinal Endoscopy - March 15, 2012 Category: Gastroenterology Authors: Paulo F.S. Bittencourt, Raquel S. Malheiros, Alexandre R. Ferreira, Simone D. Carvalho, Paulo P.F. Filho, Edson S. Tatsuo, Fernando F. Mattos, Suzan O. Melo, Walton Albuquerque, Vitor Arantes, Luiz R. Alberti Tags: Brief Reports Source Type: research

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The goal of this retrospective comparative study was to determine the effect of transanastomotic tube (TAT) feeding on outcome after repair of congenital duodenal obstruction (CDO). All infants with CDO older than 10 years were included. Data are presented as median (range). Mann-Whitney U test and Fisher's Exact test were used. Of 55 infants with CDO (48 atresia, 7 stenosis), 17 were managed with a TAT, 38 without. Enteral feeds were commenced earlier in infants with a TAT compared with those without (TAT 2 days postrepair [1-4] vs no-TAT 3 days postrepair [1-7]; P = .006). Infants with a TAT achieved full enteral feeds s...
Source: Journal of Pediatric Surgery - March 1, 2012 Category: Surgery Authors: Federico G. Seifarth Tags: International Abstracts of Pediatric Surgery Source Type: research

Spastic quadriplegia in Down syndrome with congenital duodenal stenosis/atresia
AbstractDown syndrome is an autosomal chromosome disorder, characterized by intellectual disability and muscle hypotonia. Muscle hypotonia is observed from neonates to adulthood in Down syndrome patients, but muscle hypertonicity is extremely unusual in this syndrome. During a study period of 9 years, we found three patients with severe spastic quadriplegia among twenty cases with Down syndrome and congenital duodenal stenosis/atresia (3/20). However, we could find no patient with spastic quadriplegia among 644 cases with Down syndrome without congenital duodenal stenosis/atresia during the same period (0/644, p<0.05). ...
Source: Congenital Anomalies - February 10, 2012 Category: Genetics & Stem Cells Authors: Kenji Kurosawa, Keisuke Enomoto, Makiko Tominaga, Noritaka Furuya, Kiyoko Sameshima, Mizue Iai, Hiroshi Take, Masato Shinkai, Hiroshi Ishikawa, Michiko Yamanaka, Kiyoshi Matsui, Mitsuo Masuno Source Type: research

Bile duct duplication as a cause of distal bowel gas in neonatal duodenal obstruction
Conclusions: Neonatal DA presenting with distal bowel gas via an anomalous bifurcated bile duct conduit is more common than initially thought and occurs more frequently than duodenal stenosis. These patients might be at risk for cholestasis, possibly owing to duodeno-biliary reflux through the ampulla. (Source: Journal of Pediatric Surgery)
Source: Journal of Pediatric Surgery - December 1, 2011 Category: Surgery Authors: Hiroaki Komuro, Kentaro Ono, Noriko Hoshino, Yasuhisa Urita, Chikashi Gotoh, Jun Fujishiro, Toko Shinkai, Ken-ichi Ikebukuro Tags: PAPS Papers Source Type: research

Pancreatic carcinoma masquerading as groove pancreatitis: case report and review of literature.
CONCLUSION: Several studies have been attempted to clarify the points of differentiation between carcinoma and pancreatitis in the groove area. This discrimination has been proved to be difficult; frequently the definitive diagnosis is only obtained after surgical intervention. This condition should be considered when making the differential diagnosis in pancreatic groove pathology and duodenal stenosis. PMID: 22072250 [PubMed - in process] (Source: JOP)
Source: JOP - November 20, 2011 Category: Gastroenterology Authors: Malde DJ, Oliveira-Cunha M, Smith AM Tags: JOP Source Type: research

Double bubble sign
A 4-day-old full-term male neonate presented with postprandial non-bilious vomiting. Delayed meconium passage had been recorded at 36 h of age. Progressive abdominal distention was noted. A supine radiograph of the abdomen showed marked distention of the stomach and proximal duodenum with double bubble sign (figure 1). Air density was not identified distal to the duodenum. Duodenal obstruction was strongly suspected. Exploratory laparotomy revealed duodenal atresia proximal to the ampulla of Vater and severe dilatation in the first part of the duodenum, which were repaired by duodenoduodenostomy. The double bubble sig...
Source: Emergency Medicine Journal - November 18, 2011 Category: Emergency Medicine Authors: Yang, H.-C., Chen, S.-J., Liu, K.-L. Tags: Pancreas and biliary tract, Small intestine, Radiology, Clinical diagnostic tests, Radiology (diagnostics), Ethics Images in emergency medicine Source Type: research

Temporary placement of stent grafts in postsurgical benign biliary strictures: a single center experience.
CONCLUSION: Treatment of benign biliary strictures with temporary placement of stent-grafts has a positive effect, but is less successful in patients with strictures developed following a liver transplant. PMID: 22043153 [PubMed - in process] (Source: Korean J Radiol)
Source: Korean J Radiol - November 1, 2011 Category: Radiology Authors: Vellody R, Willatt JM, Arabi M, Cwikiel WB Tags: Korean J Radiol Source Type: research

Superobese and super-superobese patients: 2-step laparoscopic duodenal switch
Conclusion: In the treatment of superobese and super-superobese patients with 2-step LBPD/DS, we experienced no deaths and achieved acceptable morbidity, considering the high operative risk in this group. This procedure is effective for both weight loss and resolution of co-morbidities. (Source: Surgery for Obesity and Related Diseases)
Source: Surgery for Obesity and Related Diseases - September 19, 2011 Category: Surgery Authors: Giovanni Dapri, Guy Bernard Cadière, Jacques Himpens Tags: Original Articles Source Type: research

Superobese and super-superobese patients: 2-step laparoscopic duodenal switch.
CONCLUSION: In the treatment of superobese and super-superobese patients with 2-step LBPD/DS, we experienced no deaths and achieved acceptable morbidity, considering the high operative risk in this group. This procedure is effective for both weight loss and resolution of co-morbidities. PMID: 22014481 [PubMed - as supplied by publisher] (Source: Surgery for Obesity and Related Diseases : official journal of the American Society for Bariatric Surgery)
Source: Surgery for Obesity and Related Diseases : official journal of the American Society for Bariatric Surgery - September 17, 2011 Category: Surgery Authors: Dapri G, Cadière GB, Himpens J Tags: Surg Obes Relat Dis Source Type: research

Gastrectomy with isoperistaltic jejunal parallel pouch in a 15-year-old adolescent boy with gastric adenocarcinoma and autosomal recessive agammaglobulinemia
Abstract: A 15-year-old adolescent boy with autosomal recessive agammaglobulinemia underwent endoscopy because of unexplained growth failure and malnutrition. Esophagogastroduodenoscopy revealed antropyloric stenosis, and a biopsy showed an invasive gastric adenocarcinoma. Chronic atrophic corpus gastritis type A and Helicobacter pylori were also identified. Abdominal magnetic resonance imaging confirmed the stenosis resulting from a semicircular intramural tumor without obvious local or distant metastatic spread. Gastrectomy with an extended lymphadenectomy was performed. Esophagoduodenal continuity was restored by an int...
Source: Journal of Pediatric Surgery - September 1, 2011 Category: Surgery Authors: Jan E. Slotta, Sabine Heine, Anne Kauffels, Thomas Krenn, Frank Grünhage, Mathias Wagner, Norbert Graf, Martin K. Schilling, Jochen Schuld Tags: Journal of Pediatric Surgery Electronic Pages (Available only online at www.jpedsurg.org) Source Type: research

Carcinoid of the minor duodenal papilla causing upper GI bleeding
An 80-year-old woman with a history of hypertension, aortic stenosis, and chronic renal failure was referred to our unit because of hematemesis. Gastroscopy showed a polypoid lesion in the second duodenal portion, and duodenoscopy demonstrated a firm mass resembling an enlarged major papilla. Forceps biopsy was reported as insufficient for diagnosis. EUS identified a 12-mm heterogeneous, hypoechoic mass that seemed to involve the submucosa (, white arrow). A second duodenoscopy clarified it as the minor papilla, which was clearly prominent and eroded (), and it was completely resected with snare. Histopathological analysis...
Source: Gastrointestinal Endoscopy - August 16, 2011 Category: Gastroenterology Authors: David Nicolás-Pérez, Antonio Z. Gimeno-García, Hugo Alvarez-Argüelles Cabrera, Antonio Martín-Herrera, Enrique Quintero-Carrión Tags: At the Focal Point Source Type: research

Endoscopic Submucosal Dissection of Gastric Neoplasia Involving the Pyloric Channel by Retroflexion in the Duodenum
Conclusions Tumors involving the pyloric channel could be successfully resected by ESD using retroflexion in the duodenum without severe complication. This technique appears to be a feasible and effective method for the treatment of tumors involving the pyloric channel. Content Type Journal ArticlePages 1-7DOI 10.1007/s10620-011-1863-zAuthors Chul-Hyun Lim, Division of Gastroenterology, Department of Internal Medicine, The Catholic University of Korea College of Medicine, #505, Banpo-dong, Seocho-gu, Seoul, 137-701 KoreaJae Myung Park, Division of Gastroenterology, Department of Internal Medicine, T...
Source: Digestive Diseases and Sciences - August 13, 2011 Category: Gastroenterology Tags: Digestive Diseases and Sciences Source Type: research

Duodenal variceal bleeding caused by chronic pancreatitis
A 73-year-old man with no history of hepatitis B virus, hepatitis C virus, alcoholism, or cirrhosis was admitted because of tarry stool passage for 1 day. He had been diagnosed 7 years earlier as having gallstones, which induced acute necrotizing pancreatitis complicated with pseudocyst formation. On this admission, his pulse rate was 100 beats per minute and blood pressure was 152/79 mm Hg. Physical examination revealed pale conjunctiva and tachycardia. Laboratory test results were as follows: hemoglobin 9.9 g/dL, platelet count 104,000/mm3, white blood cell count 3600/mm3, alanine aminotransferase 23 IU/L, total bilirubi...
Source: Gastrointestinal Endoscopy - August 1, 2011 Category: Gastroenterology Authors: Wei-Yu Kao, Wen-Chieh Wu, Ping-Hsien Chen, Yi-You Chiou Tags: Brief Reports Source Type: research

Shock Bowel Caused by Neurogenic Shock: Computed Tomography Findings
A 47-year-old previously healthy man presented to the Emergency Department with a chief complaint of neck pain and sensory changes below the nipple line. He had crashed into a guardrail while driving his car at high speed 5 hours earlier. The patient first presented to a local hospital near the accident. The patient was transferred to our hospital, and had a 3-h transport time. He was alert but complained of abdominal pain. Vital signs included a systolic blood pressure of 60 mm Hg, pulse of 81 beats/min, respiratory rate of 20 breaths/min, and body temperature of 36.2°C. The physical examination revealed a left knee woun...
Source: The Journal of Emergency Medicine - June 10, 2011 Category: Emergency Medicine Authors: Oh Young Kwon, Jong Seok Lee, Han Sung Choi, Hoon Pyo Hong, Young Gwan Ko Tags: Visual Diagnosis in Emergency Medicine Source Type: research

Duodenal metastasis from recurrent invasive lobular carcinoma of breast: a case report and literature review
We present a rare case of duodenal metastasis from invasive breast lobular carcinoma, which first presented clinically as elevated serum tumor marker levels, followed by jaundice but with no other clinical evidence of recurrence and metastasis. A 53-year-old woman underwent modified radical mastectomy of the left breast (pT2 N3 M0 stage III c) followed by postoperative chemo-radiotherapy and hormonal therapy. After about 3 years, the patient presented with elevated serum tumor marker levels and mild jaundice. She was subsequently admitted to the hospital for nausea and severe vomiting. A duodenoscopy revealed the ...
Source: International Journal of Clinical Oncology - June 3, 2011 Category: Cancer & Oncology Tags: International Journal of Clinical Oncology Source Type: research

Isolated congenital tracheal stenosis in a preterm newborn
Conclusion Successful treatment of severe congenital tracheal stenosis and tracheal atresia depends on either prenatal diagnosis or recognition of this condition immediately after birth to perform tracheotomy without delay. Nevertheless, despite any efforts, the therapeutical results of severe tracheal stenosis and tracheal atresia are still unsatisfactory. Content Type Journal ArticlePages 1-5DOI 10.1007/s00431-011-1490-xAuthors Ulrich Krause, Department of Pediatric Cardiology and Intensive Care Medicine, University Hospital, Georg-August-University, Robert-Koch-Str. 40, 37099 Göttingen, GermanyRalph M. W. Röd...
Source: European Journal of Pediatrics - May 18, 2011 Category: Pediatrics Tags: European Journal of Pediatrics Source Type: research

Empiric Transcatheter Arterial Embolization for Massive Bleeding From Duodenal Ulcers: Efficacy and Complications
Conclusions: A high rate of technical and clinical success was obtained with empiric TAE comparable to identifiable TAE in patients with massive bleeding from duodenal ulcers. There were no severe complications. Empiric TAE is an effective and safe method when a bleeding site cannot determined by angiography. (Source: Journal of Vascular and Interventional Radiology : JVIR)
Source: Journal of Vascular and Interventional Radiology : JVIR - May 15, 2011 Category: Radiology Authors: Ikushima Ichiro, Higashi Shushi, Ishii Akihiko, Iryo Yasuhiko, Yamashita Yasuyuki Source Type: research

Trans-anastomotic tubes reduce the need for central venous access and parenteral nutrition in infants with congenital duodenal obstruction
Conclusions A TAT significantly shortens time to full enteral feeds in infants with CDO significantly reducing the need for central venous access and PN. Content Type Journal ArticlePages 1-5DOI 10.1007/s00383-011-2896-2Authors N. J. Hall, Wessex Regional Centre for Paediatric Surgery, Southampton University Hospitals NHS Trust, Mailpoint 44, Tremona Road, Southampton, SO16 6YD UKM. Drewett, Wessex Regional Centre for Paediatric Surgery, Southampton University Hospitals NHS Trust, Mailpoint 44, Tremona Road, Southampton, SO16 6YD UKR. A. Wheeler, Wessex Regional Centre for Paediatric Surgery, Southam...
Source: Pediatric Surgery International - April 8, 2011 Category: Surgery Tags: Pediatric Surgery International Source Type: research

An Unusual Case of Duodenal Stenosis
Question: A 57-year-old woman was admitted to our unit complaining of abrupt onset of upper abdominal pain, nausea, and vomiting. Her symptoms occurred the previous evening and worsened throughout the day until sudden onset of severe upper abdominal fullness and vomiting. She had no history of abdominal trauma, pancreatitis, alcohol abuse, previous surgery, or other specific disease, except for mild hypertension. Upon admission, she had tenderness and muscle defense in the upper to umbilical portion of the abdomen. Laboratory findings revealed a C-reactive protein level of 29 mg/L, an elevation of the serum amylase level (...
Source: Gastroenterology - April 3, 2011 Category: Gastroenterology Authors: Teresa Staiano, Roberto Grassia, Giuseppe Voltini Tags: Clinical Challenges and Images in GI Source Type: research

Retinaldehyde dehydrogenase 2 is Down-Regulated During Duodenal Atresia Formation in Fgfr2IIIb-/- Mice
Conclusions: In Fgfr2IIIb-/- mouse embryos, a reduction of Raldh2 expression is observed within the region that is forming the atresia. This is the first demonstration of such an event in this model. As in humans, these results implicate disruptions between Fgfr2IIIb receptor function and RA signaling in the formation of this defect and indicate that Fgfr2IIIb-/- mouse embryos are a valid model for the study of the atretic spectrum of defects in human duodenal development. (Source: Journal of Surgical Research)
Source: Journal of Surgical Research - March 21, 2011 Category: Surgery Authors: Peter F. Nichol, John D. Tyrrell, Yukio Saijoh Tags: Pediatric/Congenital/Developmental Source Type: research

Laparoscopy-assisted subtotal gastrectomy with very small remnant stomach: a novel surgical procedure for selected early gastric cancer in the upper stomach
Abstract Total gastrectomy or proximal gastrectomy is usually performed either as an open procedure or laparoscopically for the treatment of early gastric cancer (EGC) in the upper stomach. However, quality of life after either total or proximal gastrectomy is not so satisfactory. The authors report a novel surgical procedure, laparoscopy-assisted subtotal gastrectomy (LAsTG), by which a very small remnant stomach is preserved, for the surgery of selected EGCs in the upper stomach. Twenty-three patients with EGC in the upper stomach underwent LAsTG. After lymph node dissection and mobilization of the stomach...
Source: Gastric Cancer - February 23, 2011 Category: Gastroenterology Tags: Gastric Cancer Source Type: research

A novel association of alveolar capillary dysplasia, atypical duodenal atresia, and subglottic stenosis
This report highlights the hazards of the onset and worsening of ACD, and the importance of thorough echocardiography before surgery when atypical duodenal atresia is suspected. Anesthesiologists should also be prepared for the difficulty of intubation. Content Type Journal ArticleDOI 10.1007/s00540-010-1080-5Authors Takeru Shimizu, Department of Anesthesiology and Critical Care Medicine, Graduate School of Comprehensive Human Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575, JapanTaeko Fukuda, Department of Anesthesiology and Critical Care Medicine, Graduate School of Comprehensive Human...
Source: Journal of Anesthesia - December 30, 2010 Category: Anesthesiology Tags: Journal of Anesthesia Source Type: research

A Newly Developed Variable Stiffness Duodenoscope for Diagnostic and Therapeutic Endoscopic Retrograde Cholangiopancreatography
In conclusion, while the VSD performed well, the present models do not appear to offer obvious advantages over the standard duodenoscopes for routine diagnostic and therapeutic ERCP. Prospective studies may be warranted to identify those patients who would benefit from this new technology. (Source: Diagnostic and Therapeutic Endoscopy)
Source: Diagnostic and Therapeutic Endoscopy - December 10, 2010 Category: Surgery Source Type: research

Ectopic opening of the common bile duct and duodenal stenosis: an overlooked association
Conclusions: The presence of EO-CBD-DB should be considered particularly in middle-aged male patients who have duodenal deformity/stenosis. Endoscopic treatment is feasible in these patients. The long-term outcomes of endoscopic therapy need to be compared with surgical treatment. (Source: BioMed Central)
Source: BioMed Central - December 3, 2010 Category: Journals (General) Authors: Erkan ParlakSelcuk DisibeyazCem CengizBahattin CicekYasemin OzinSabite KacarNurgul SasmazBurhan Sahin Source Type: research

[Metastatic prostate cancer complicated with chronic disseminated intravascular coagulopathy causing acute renal failure, mimicking thrombotic thrombocytopenic purpura and hemolytic uremic syndrome: pathomechanism, differential diagnosis and therapy related to a case].
Disseminated intravascular coagulopathy (DIC) is characterized as activation of the clotting system resulting in fibrin thrombi, gradually diminishing levels of clotting factors with increased risk of bleeding. Basically two types of DIC are distinguished: (1) chronic (compensated) - with alteration of laboratory values and (2) acute (non-compensated) - with severe clinical manifestations: bleeding, shock, acute renal failure (ARF), transient focal neurologic deficit, delirium or coma. Chronic DIC related to metastatic neoplasia is caused by pancreatic, gastric or prostatic carcinoma in most of the cases. Incidence rat...
Source: Magyar Onkologia - November 30, 2010 Category: Cancer & Oncology Authors: Deme D, Ragán M, Kalmár K, Kovács L, Varga E, Varga T, Rakonczai E Tags: Magy Onkol Source Type: research

[Metastatic prostate cancer complicated with chronic disseminated intravascular coagulopathy causing acute renal failure mimicking thrombotic thrombocytopenic purpura and hemolytic uremic syndrome: pathomechanism, differential diagnosis and therapy related to a case.]
Disseminated intravascular coagulopathy (DIC) is characterized as activation of the clotting system resulting in fibrin thrombi, gradually diminishing levels of clotting factors with increased risk of bleeding. Basically two types of DIC are distinguished: (1) chronic (compensated) - with alteration of laboratory values and (2) acute (non-compensated) - with severe clinical manifestations: bleeding, shock, acute renal failure (ARF), transient focal neurologic deficit, delirium or coma. Chronic DIC related to metastatic neoplasia is caused by pancreatic, gastric or prostatic carcinoma in most of the cases. Incidence rat...
Source: Magyar Onkologia - November 30, 2010 Category: Cancer & Oncology Authors: Deme D, Ragán M, Kalmár K, Kovács L, Varga E, Varga T, Rakonczai E Tags: Magy Onkol Source Type: research

Pancreatic resection for metastasis to the pancreas from colon and lung cancer, and osteosarcoma.
CONCLUSION: Pancreatic resection for metastatic disease may be suggested for selected patients, even those with limited extrapancreatic disease. In this setting, it may offer good palliation and may prolong survival. In cases of acute duodenal bleeding resistant to conservative measures, pancreaticoduodenectomy may represent the only alternative for survival; however, significant morbidity and mortality should be expected. PMID: 21068492 [PubMed - in process] (Source: JOP)
Source: JOP - November 12, 2010 Category: Gastroenterology Authors: Lasithiotakis K, Petrakis I, Georgiadis G, Paraskakis S, Chalkiadakis G, Chrysos E Tags: JOP Source Type: research

Duodenal switch with omentopexy and feeding jejunostomy—a safe and effective revisional operation for failed previous weight loss surgery
Conclusion: Revisional surgery to a duodenal switch is a complex operation and carries a high potential for major complications. Nonetheless, it can be accomplished safely with good long-term results. Omentopexy, drainage, and feeding jejunostomy should be considered at surgery to treat the high potential for delayed ischemic leaks. (Source: Surgery for Obesity and Related Diseases)
Source: Surgery for Obesity and Related Diseases - November 10, 2010 Category: Surgery Authors: David F. Greenbaum, Samuel H. Wasser, Tina Riley, Tinamarie Juengert, June Hubler, Karen Angel Tags: Original Articles Source Type: research

Endosonography-Guided Biliary Drainage with One-Step Placement of a Newly Developed Fully Covered Metal Stent Followed by Duodenal Stenting for Pancreatic Head Cancer
An 83-year-old man was admitted to our department, presenting with jaundice, fever, and nausea. CT revealed a pancreatic head tumor with duodenal invasion. Endoscopic transpapillary biliary drainage was unsuccessful due to stenosis at the second portion of the duodenum and tumor invasion to the papilla of Vater. Using a convex linear array echoendoscope, a fully-covered metal stent was placed across the puncture tract to bridge the duodenum and the bile duct. After improvement of jaundice, a duodenal metal stent was placed across the stricture of the duodenum. No procedure-related complications occurred. Neither migration ...
Source: Diagnostic and Therapeutic Endoscopy - October 19, 2010 Category: Surgery Source Type: research

Complications of Congenital and Developmental Abnormalities of the Gastrointestinal Tract in Adolescents and Adults: Evaluation with Multimodality Imaging [Gastrointestinal Imaging]
There is a wide variety of congenital anomalies that may affect the gastrointestinal tract. Most symptomatic congenital anomalies are found in newborns and infants. Such anomalies are relatively rare in adolescents and adults, and they may be difficult to identify because clinical symptoms often are nonspecific and insidious, causing them to be mistaken for other common abdominal conditions. Multimodality imaging is useful in evaluating congenital anomalies of the gastrointestinal tract in adults. The imaging features at radiography, fluoroscopy, ultrasonography, computed tomography, and magnetic resonance imaging may help...
Source: Radiographics recent issues - October 12, 2010 Category: Radiology Authors: Lee, N. K., Kim, S., Jeon, T. Y., Kim, H. S., Kim, D. H., Seo, H. I., Park, D. Y., Jang, H. J. Tags: Gastrointestinal Radiology Gastrointestinal Imaging Source Type: research

Sphincterotome stricturoplasty for long ampullary stenoses and benign biliary strictures (with video)
Conclusions Compared with balloon stricturoplasty ± biliary stenting, SS is a simple and cost-effective alternative option in managing long ampullary stenosis and/or distal fibrotic biliary stricture during the initial ERCP. Content Type Journal ArticleDOI 10.1007/s00464-010-1340-3Authors Shou-jiang Tang, Division of Gastroenterology, University of Mississippi Medical Center, 2500 North State Street, Jackson, MS 39216, USASundeep Singh, Division of Gastroenterology, University of Mississippi Medical Center, 2500 North State Street, Jackson, MS 39216, USAShailender Singh, Division of Gastro...
Source: Surgical Endoscopy - September 11, 2010 Category: Surgery Tags: Surgical Endoscopy Source Type: research

Laparoscopic repeat sleeve gastrectomy versus duodenal switch after isolated sleeve gastrectomy for obesity
Conclusion: The results of the present study have shown that laparoscopic re-SG is feasible but carries the risk of fistula development, which is difficult to treat. Laparoscopic DS was also shown to be feasible at a cost of not negligible complications, which are easier to manage than with re-SG. The efficacy seemed greater after DS than after re-SG. (Source: Surgery for Obesity and Related Diseases)
Source: Surgery for Obesity and Related Diseases - August 19, 2010 Category: Surgery Authors: Giovanni Dapri, Guy Bernard Cadière, Jacques Himpens Tags: Original Articles Source Type: research

De novo pericentric inversion of chromosome 9 in congenital anomaly.
Conclusion: Since our results indicate that the incidence of inv(9)(p11q13) in patients with congenital anomalies was not significantly different from the normal population, inv(9)(p11q13) does not appear to be pathogenic with regard to the congenital anomalies. Some other, to date unknown, causes of the anomalies remain to be identified. PMID: 20635455 [PubMed - in process] (Source: Yonsei Medical Journal)
Source: Yonsei Medical Journal - July 18, 2010 Category: Universities & Medical Training Authors: Jeong SY, Kim BY, Yu JE Tags: Yonsei Med J Source Type: research

Endoscopic ultrasound-guided transduodenal placement of a fully covered metal stent for palliative biliary drainage in patients with malignant biliary obstruction
Conclusions EUSBD with a fully covered SEMS in whom ERCP is unsuccessful is effective for palliation of biliary obstruction. The limitations of our study are that we had a small number of patients and a limited follow-up time. Content Type Journal ArticleDOI 10.1007/s00464-010-1216-6Authors Ali A. Siddiqui, Dallas Veterans Affairs Medical Center Department of Internal Medicine 4500 S. Lancaster Road (111B1) Dallas TX 75216 USAJayaprakash Sreenarasimhaiah, Dallas Veterans Affairs Medical Center Department of Internal Medicine 4500 S. Lancaster Road (111B1) Dallas TX 75216 USALuis F. Lara, Baylor Medic...
Source: Surgical Endoscopy - July 16, 2010 Category: Surgery Tags: Surgical Endoscopy Source Type: research

Umbilical crease incision for duodenal atresia achieves excellent cosmetic results
Conclusions The outcome of duodenal atresia is satisfactory with excellent cosmesis after a duodenoduodenostomy performed via the umbilical crease incision. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00383-010-2645-yAuthors Yukiko Takahashi, Kyushu University Department of Pediatric Surgery, Graduate School of Medical Sciences 3-1-1 Maidashi, Higashi-ku Fukuoka 812-8582 JapanTatsuro Tajiri, Kyushu University Department of Pediatric Surgery, Graduate School of Medical Sciences 3-1-1 Maidashi, Higashi-ku Fukuoka 812-8582 JapanKouji Masumoto, Kyushu University Department of Pediat...
Source: Pediatric Surgery International - July 11, 2010 Category: Surgery Tags: Pediatric Surgery International Source Type: research