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Genital Herpes May Never Go DormantEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Title: Genital Herpes May Never Go DormantCategory: Health NewsCreated: 11/18/2009 4:10:00 PMLast Editorial Review: 11/19/2009 (Source: MedicineNet Womens Health General)
Source: MedicineNet Womens Health General - November 19, 2009 Category: OBGYN Source Type: consumer

Circumcision and Risk of Sexually Transmissible Infections in a Community-Based Cohort of HIV-Negative Homosexual Men in Sydney, Australia.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions. These are the first prospective data obtained from homosexual men to assess circumcision status as a risk factor for STIs. Circumcised men were at reduced risk of incident syphilis but no other prevalent or incident STIs. Circumcision is unlikely to have a substantial public health impact in reducing acquisition of most STIs in homosexual men. PMID: 19911990 [PubMed - as supplied by publisher] (Source: Herpes)
Source: Herpes - November 19, 2009 Category: Infectious Diseases Authors: Templeton DJ, Jin F, Prestage GP, Donovan B, Imrie JC, Kippax SC, Cunningham PH, Kaldor JM, Mindel A, Cunningham AL, Grulich AE Tags: J Infect Dis Source Type: journals

Herpes Virus Shedding Studied With Mathematical ModelEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
People infected with herpes simplex virus 2 experience almost constant releases of small numbers of viruses from the neurons that host them into the genital tract, which may make prevention of person-to-person transmission difficult, according to a mathematical model of HSV-2 behavior described in a paper published online Nov. 18 in Science Translational Medicine. (Source: Modern Medicine)
Source: Modern Medicine - November 19, 2009 Category: Journals (General) Source Type: info

Genital Herpes May Never Go DormantEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Study finds low level shedding may be continuous, infection state unclear Source: HealthDay Related MedlinePlus Topic: Herpes Simplex (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - November 18, 2009 Category: Consumer Health News Source Type: consumer

AIDS, UTI, Herpes Vaccines May Exist In 5 YearsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Malaria. Tuberculosis. Alzheimer's disease. AIDS. Pandemic flu. Genital herpes. Urinary tract infections. Grass allergies. Traveler's diarrhea. You name it, the pharmaceutical industry is working on a vaccine to prevent it. Many could be on the market in five years or less. Contrast that with five years ago, when so many companies had abandoned the vaccine business that half the U.S. supply of flu shots was lost because of factory contamination at one of the two manufacturers left. (Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire)
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - November 18, 2009 Category: Consumer Health News Source Type: consumer

Vaccines on horizon for Alzheimer's, herpes, AIDSEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Malaria. Tuberculosis. Alzheimer's disease. AIDS. Pandemic flu. Genital herpes. Urinary tract infections. Grass allergies. Traveler's diarrhea. You name it, the pharmaceutical industry is working on a vaccine to prevent it. (Source: CTV Health)
Source: CTV Health - November 18, 2009 Category: Consumer Health News Source Type: news

Vaccines on Horizon for AIDS, Alzheimer's, HerpesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
From Associated Press (November 18, 2009) MARIETTA, Pa._Malaria. Tuberculosis. Alzheimer's disease. AIDS. Pandemic flu. Genital herpes. Urinary tract infections. Grass allergies. Traveler's diarrhea. You name it, the pharmaceutical industry is... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - November 18, 2009 Category: Pharmaceuticals Source Type: news

Vaccines for AIDS, Alzheimer's, herpes on the horizonEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Malaria. Tuberculosis. Alzheimer's disease. AIDS. Pandemic flu. Genital herpes. Urinary tract infections. Grass allergies. Traveler's diarrhea. You name it, the pharmaceutical industry is working on a vaccine to prevent it. Many could be on the market in... (Source: OrlandoSentinel: Medical Research)
Source: OrlandoSentinel: Medical Research - November 18, 2009 Category: American Health Source Type: news

Vaccines On Horizon For AIDS, Alzheimer's, HerpesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Malaria. Tuberculosis. Alzheimer's disease. AIDS. Pandemic flu. Genital herpes. Urinary tract infections. Grass allergies. Traveler's diarrhea. You name it, the pharmaceutical industry is working on a vaccine to prevent it. (Source: WDSU.com - Health)
Source: WDSU.com - Health - November 17, 2009 Category: Consumer Health News Authors: WDSU.com Source Type: news

'Golden era' could bring vaccines against AIDS, Alzheimer's and addictions within 5 yearsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
MARIETTA, Pa. (AP) — Malaria. Tuberculosis. Alzheimer's disease. AIDS. Pandemic flu. Genital herpes. Urinary tract infections. Grass allergies. Traveler's diarrhea. You name it, the pharmaceutical industry is working on a vaccine to prevent it.... (Source: OrlandoSentinel: Medical Research)
Source: OrlandoSentinel: Medical Research - November 17, 2009 Category: American Health Source Type: news

Circumcision and Risk of Sexually Transmissible Infections in a Community‐Based Cohort of HIV‐Negative Homosexual Men in Sydney, AustraliaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions. These are the first prospective data obtained from homosexual men to assess circumcision status as a risk factor for STIs. Circumcised men were at reduced risk of incident syphilis but no other prevalent or incident STIs. Circumcision is unlikely to have a substantial public health impact in reducing acquisition of most STIs in homosexual men. (Source: The Journal of Infectious Diseases Latest Issue)
Source: The Journal of Infectious Diseases Latest Issue - November 13, 2009 Category: Infectious Diseases Tags: article MAJOR ARTICLE Source Type: journals

Newer trends in the management of genital herpesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Nath Amiya Kumar, Thappa Devinder MohanIndian Journal of Dermatology, Venereology, and Leprology 2009 75(6):566-574Management of genital herpes is complex. Apart from using the standard antivirals, an ideal management protocol also needs to address various aspects of the disease, including the psychological morbidity. Oral acyclovir, valacyclovir or famciclovir are recommended for routine use. Long-term suppressive therapy is effective in reducing the number of recurrences and the risk of transmission to others. Severe or disseminated disease may require intravenous therapy. Resistant cases are managed with foscarnet or ci...
Source: Indian Journal of Dermatology, Venereology and Leprology - November 12, 2009 Category: Dermatology Authors: Nath Amiya Kumar, Thappa Devinder Mohan Source Type: journals

Does circumcision influence recurrences in herpes genitalis?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Six patients and six controls did not follow-up. Seven patients reported no recurrences during 3-18 years, seven patients had two to six recurrences during 11-27 years of postcircumcision follow-up, 0.0080 (average) recurrences per person per year as compared with 0.20 (average) recurrences per person per year recorded before the circumcision. Two patients had first recurrence 11 years after the circumcision. In comparison, 14 controls had 0.17 (average) recurrences per person per year, comparable with the number of recurrences in uncircumcised patients, and frequently at shorter interv...
Source: Indian Journal of Dermatology, Venereology and Leprology - November 12, 2009 Category: Dermatology Authors: Jerath V P, Mahajan Vikram K Source Type: journals

FSL-1, a bacterial-derived toll-like receptor 2/6 agonist, enhances resistance to experimental HSV-2 infectionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: The results showed, for the first time, that the bacterial-derived TLR2/6 agonist FSL-1 induced significant resistance to HSV-2 infection when applied in mice or human vaginal EC cultures. Cytokine evaluation illustrated that anti-herpetic activity correlated with induction of a specific profile. The identified anti-herpetic profile provides an invaluable resource for the future design of novel compounds to reduce genital HSV-2 transmission and improves understanding of the complex innate immune response to potential pathogens elicited by the vaginal mucosa. (Source: BioMed Central)
Source: BioMed Central - November 10, 2009 Category: Journals (General) Authors: William RoseChris McGowinRichard Pyles Source Type: journals

New concepts in understanding genital herpesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract Herpes simplex virus (HSV)-2 is a lifelong infection that causes recurrent genital ulcers and, rarely, disseminated and visceral disease. HSV-1 infection is an increasingly important cause of genital ulcers. HSV infections are the most common cause of genital ulcers in adults, but acquisition and chronic infection are more commonly asymptomatic than symptomatic. Both the symptomatic and asymptomatic forms of HSV are of clinical consequence for several reasons. HSV-2 infection enhances HIV-1 acquisition and transmission. In addition, sexual and perinatal transmission can occur during asymptomatic vir...
Source: Current Infectious Disease Reports - November 5, 2009 Category: Infectious Diseases Tags: Current Infectious Disease Reports Source Type: journals

Pattern of sexually transmitted infections in a tertiary care centre at PuducherryEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Herpes genitalis was the most common ulcerative STD, while genital wart was the most common nonulcerative STI in our study. The prevalence of HIV among STI clients in India has been on the rise, but has quite alarmingly become the most common STI in our study. (Source: Indian Journal of Dermatology)
Source: Indian Journal of Dermatology - November 5, 2009 Category: Dermatology Authors: Devi S Abarna, Vetrichevvel T P, Pise Gajanan A, Thappa Devinder Mohan Source Type: journals

Genital herpes: an Internet-based risk surveyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Genital herpes is one of the most common sexually transmitted infections worldwide. We established a web-based survey to determine risk for genital herpes and encourage people to attend for herpes simplex virus testing. A survey was established on the Australian Herpes Management Forum (AHMF) website, consisting of 16 demographic and sexual health-related questions. Each question carried a numerical risk-weighting based on epidemiological data; the higher the overall score, the greater the risk of herpes. To determine how representative our sample was in relation to age and sex, we compared our survey with Australian Censu...
Source: International Journal of STD and AIDS - October 30, 2009 Category: Global & Universal Authors: Mindel, A, McHugh, L, Christie, E, Chung, C, Berger, T Tags: Original research articles Source Type: journals

HLA-DRB1*01 allele and low plasma IgG1 concentration may predispose to herpes-associated recurrent lymphocytic meningitis.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Recurrent lymphocytic meningitis (RLM) is a rare illness caused mostly by herpes simplex virus type 2 (HSV-2). Predisposing factors are not known. Deficiencies in immunoglobulin G subclasses 1 (IgG1) and 3 (IgG3), and complement protein C4 are associated with susceptibility to, and persistence of bacterial and viral infections. Selected HLA and mannose-binding lectin (MBL) alleles have previously been associated with recurrent genital herpes or herpetic meningitis. We assessed the frequencies of low IgG1 and IgG3, their allotypes (Gm), HLA-A*, -B*, -DRB1* and MBL2 alleles, and deficiencies in C4A and C4B genes, as pote...
Source: Human Immunology - October 29, 2009 Category: Allergy & Immunology Authors: Kallio-Laine K, Seppänen M, Aittoniemi J, Kautiainen H, Seppälä I, Valtonen V, Färkkilä M, Kalso E, Lokki ML Tags: Hum Immunol Source Type: journals

Condoms Prevent Herpes Simplex Virus Type 2Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Can consistent condom use help lessen the chance of contracting genital herpes? This meta-analysis provides some answers. Journal Watch (Source: Medscape Med Students Headlines)
Source: Medscape Med Students Headlines - October 23, 2009 Category: Universities & Medical Training Tags: Internal Medicine Source Type: info

Immune reconstitution inflammatory syndrome involving the skinEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions. New skin lesions were very common in this cohort, with the majority being women and patients with very low baseline CD4 counts. (Source: Clinical And Experimental Dermatology)
Source: Clinical And Experimental Dermatology - October 22, 2009 Category: Dermatology Authors: B. Osei-Sekyere, A. S. Karstaedt Source Type: journals

Increasing role of herpes simplex virus type 1 in first-episode anogenital herpes in heterosexual women and younger men who have sex with men, 1992-2006 [Epidemiology]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: The proportion of first-episode anogenital herpes due to HSV-1 significantly increased among younger MSM and heterosexual women over the 15-year period. In some clinical populations, such as young MSM and women or patients with anal disease, HSV-1 may now account for the majority of first-episode anogenital herpes. (Source: Sexually Transmitted Infections)
Source: Sexually Transmitted Infections - October 13, 2009 Category: Sexual Medicine Authors: Ryder, N, Jin, F, McNulty, A M, Grulich, A E, Donovan, B Tags: Drugs: infectious diseases, HIV/AIDS, HIV / AIDS, HIV infections, herpes simplex virus, Health education Epidemiology Source Type: journals

Increasing role of herpes simplex virus type 1 in first-episode anogenital herpes in heterosexual women and younger men who have sex with men, 1992-2006Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: The proportion of first-episode anogenital herpes due to HSV-1 significantly increased among younger MSM and heterosexual women over the 15-year period. In some clinical populations, such as young MSM and women or patients with anal disease, HSV-1 may now account for the majority of first-episode anogenital herpes. (Source: Sexually Transmitted Infections)
Source: Sexually Transmitted Infections - October 13, 2009 Category: Sexual Medicine Authors: Ryder, N, Jin, F, McNulty, A M, Grulich, A E, Donovan, B Tags: Drugs: infectious diseases, HIV/AIDS, HIV / AIDS, HIV infections, herpes simplex virus, Health education Epidemiology Source Type: journals

Review: Maternal and neonatal herpes infectionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Source: NEJM Area: News A comprehensive overview of maternal and neonatal herpes simplex virus (HSV) infection has been published in the New England Journal of Medicine. The authors note that neonatal HSV infection is potentially devastating - the untreated survival rate of 40%, and survivors have a high risk of serious disability. They also note the high prevalence of genital herpes in pregnant women in the US - estimated to be between 25% and 65%. The review covers the pathophysiology of HSV infection, which may involve HSV-1 or HSV-2. Transmission to the baby is most likely when the infection is newly acquir...
Source: NeLM - News - September 30, 2009 Category: Drugs & Pharmacology Source Type: organizations

Current Concepts: Maternal and Neonatal Herpes Simplex Virus InfectionsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Whether it is caused by herpes simplex virus (HSV) type 1 or type 2, neonatal HSV infection is a devastating disease if untreated, and more than 30% of pregnant women in the United States have genital infection with HSV. This review summarizes the current facts on this disease and its early identification and treatment, as well as the prospects for more effective prevention. (Source: New England Journal of Medicine)
Source: New England Journal of Medicine - September 29, 2009 Category: Internal Medicine Authors: Corey, L., Wald, A. Tags: REVIEW ARTICLES Source Type: journals

3,4‐Methylenedioxymethamphetamine Increases Susceptiblity to Genital Herpes Simplex Virus Infection in MiceEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The Journal of Infectious Diseases, Volume 0, Issue 0, Page 000, Latest Articles. Abused by >1.2 million Americans, 3,4‐methylenedioxymethamphetamine (MDMA) (commonly referred to as ecstasy) is popular in the dance club, rave, and circuit party scenes. MDMA and other similar drugs are reportedly associated with increased incidence of sexually transmitted infectious diseases, such as AIDS and genital herpes, and may have immunological effects. In the present study, we demonstrate that MDMA causes increased susceptibility to herpes simplex virus type 2 infection in mice and earlier onset of genital herpes. We also de...
Source: The Journal of Infectious Diseases Latest Issue - September 16, 2009 Category: Infectious Diseases Tags: article BRIEF REPORT Source Type: journals

Foreskin inflammation is associated with HIV and herpes simplex virus type-2 infections in Rakai, UgandaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: Foreskin inflammation is increased with HIV and HSV-2 infections, higher HIV viral load and presence of smegma. Foreskin inflammation may have implications for HIV transmission and acquisition in uncircumcised men. (C) 2009 Lippincott Williams & Wilkins, Inc. (Source: AIDS)
Source: AIDS - September 9, 2009 Category: Infectious Diseases Tags: Basic Science Source Type: journals

Review paper Genital ulcer diseases as an entry for HIV infectionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Genital ulcer diseases (GUDs) are documented agents facilitating HIV-1 infection. The main pathogens causing GUDs are: Herpes simplex virus (HSV), Treponema pallidum and Haemophilus ducreyi. It is suggested that these diseases may increase the risk of HIV transmission even a hundredfold. A few mechanisms facilitating HIV penetration into the organism are considered. The first one is disruption of the epidermis or mucous membranes, creating a physical entry point for an infection. The next one is an increased number of inflammatory infiltration cells such as macrophages and T-lymphocytes. Increased expression (up-regulation...
Source: Articles of Advances in Dermatology and Allergology - TERMEDIA publishing house - August 30, 2009 Category: Dermatology Source Type: journals

Improvement in Healing and Reduction in HIV Shedding with Episodic Acyclovir Therapy as Part of Syndromic Management among Men: A Randomized, Controlled TrialEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions. Addition of acyclovir to syndromic management will improve healing of genital ulcers and may potentially reduce HIV transmission in combination with other interventions. Trial registration. ClinicalTrials.gov identifier: NCT00164424. (Source: The Journal of Infectious Diseases Latest Issue)
Source: The Journal of Infectious Diseases Latest Issue - August 28, 2009 Category: Infectious Diseases Tags: article MAJOR ARTICLE Source Type: journals

Aetiology of genital ulcer disease in female partners of male participants in a circumcision trial in UgandaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
HIV acquisition is associated with herpes simplex virus type 2 (HSV-2) infection and genital ulcer disease (GUD). Three randomized control trials demonstrated that male circumcision significantly decreases HIV, HSV-2, human papillomavirus and self-reported GUD among men. GUD is also decreased among female partners of circumcised men, but it is unknown whether male circumcision status affects GUD pathogens in female partners. For the evaluation of GUD aetiology, two separate multiplex assays were performed to detect Haemophilus ducreyi, Treponema pallidum, HSV-1 and HSV-2. Of all the female GUD swabs evaluated, 67.5% had an...
Source: International Journal of STD and AIDS - August 25, 2009 Category: Global & Universal Authors: Brankin, A E, Tobian, A A R, Laeyendecker, O, Suntoke, T R, Kizza, A, Mpoza, B, Kigozi, G, Nalugoda, F, Iga, B, Chen, M Z, Gray, R H, Wawer, M J, Quinn, T C, Reynolds, S J Tags: Audit reports Source Type: journals

Protection from Herpes Simplex Virus (HSV)–2 Infection with Replication‐Defective HSV‐2 or Glycoprotein D2 Vaccines in HSV‐1–Seropositive and HSV‐1–Seronegative Guinea PigsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions. dl5–29 Is an effective vaccine in both HSV‐1–seropositive and HSV‐1–seronegative guinea pigs and was superior to gD2 vaccines in reducing virus shedding after challenge in both groups of animals. dl5–29 Might reduce transmission of HSV‐2. (Source: The Journal of Infectious Diseases Latest Issue)
Source: The Journal of Infectious Diseases Latest Issue - August 24, 2009 Category: Infectious Diseases Tags: article MAJOR ARTICLE Source Type: journals

Genital HerpesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: eMedicineHealth.com)
Source: eMedicineHealth.com - August 19, 2009 Category: Journals (General) Source Type: info

Why Genital Herpes Boosts the Risk of HIV InfectionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - August 17, 2009 Category: Consumer Health News Source Type: news

Once daily valacyclovir for reducing viral shedding in subjects newly diagnosed with genital herpes.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: In this study, the frequency of total and subclinical HSV-2 shedding was greater than reported in earlier studies involving subjects with a history of symptomatic genital recurrences. Our study is the first to demonstrate a significant reduction in viral shedding with valacyclovir 1 g daily compared to placebo in a population of subjects newly diagnosed with HSV-2 infection. PMID: 19680456 [PubMed - in process] (Source: Herpes)
Source: Herpes - August 17, 2009 Category: Infectious Diseases Authors: Martens MG, Fife KH, Leone PA, Dix LP, Brennan CA Tags: Infect Dis Obstet Gynecol Source Type: journals

Once Daily Valacyclovir for Reducing Viral Shedding in Subjects Newly Diagnosed with Genital HerpesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion. In this study, the frequency of total and subclinical HSV-2 shedding was greater than reported in earlier studies involving subjects with a history of symptomatic genital recurrences. Our study is the first to demonstrate a significant reduction in viral shedding with valacyclovir 1 g daily compared to placebo in a population of subjects newly diagnosed with HSV-2 infection. (Source: Infectious Diseases in Obstetrics and Gynecology)
Source: Infectious Diseases in Obstetrics and Gynecology - August 11, 2009 Category: OBGYN Source Type: journals

Why Even Treated Genital Herpes Sores Boost The Risk Of HIV InfectionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
New research helps explain why infection with herpes simplex virus-2 (HSV-2), which causes genital herpes, increases the risk for HIV infection even after successful treatment heals the genital skin sores and breaks that often result from HSV-2. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - August 7, 2009 Category: Science Source Type: news

Scientists Learn Why Even Treated Genital Herpes Sores Boost The Risk Of HIV InfectionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
New research helps explain why infection with herpes simplex virus-2 (HSV-2), which causes genital herpes, increases the risk for HIV infection even after successful treatment heals the genital skin sores and breaks that often result from HSV-2. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - August 5, 2009 Category: Consumer Health News Tags: HIV / AIDS Source Type: news

Scientists Learn Why Even Treated Genital Herpes Sores Boost the Risk of HIV InfectionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Source: National Institute of Allergy and Infectious Diseases Related MedlinePlus Topics: AIDS, Herpes Simplex (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - August 3, 2009 Category: Consumer Health News Source Type: consumer

Scientists Learn Why Even Treated Genital Herpes Sores Boost the Risk of HIV InfectionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
New research helps explain why infection with herpes simplex virus-2 (HSV-2), which causes genital herpes, increases the risk for HIV infection even after successful treatment heals the genital skin sores and breaks that often result from HSV-2. (Source: National Institutes of Health (NIH) News Releases)
Source: National Institutes of Health (NIH) News Releases - August 3, 2009 Category: American Health Source Type: news

Nodular vulvar herpes in an HIV-positive womanEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Most HIV-positive patients are coinfected with herpes simplex virus type 2. Some of these patients may present uncommon clinical manifestations, such as hypertrophic genital lesions . Nodules are rare in immunocompromised patients and there have been few reports in either sex . (Source: International Journal of Gynaecology and Obstetrics)
Source: International Journal of Gynaecology and Obstetrics - August 3, 2009 Category: OBGYN Authors: Rose Luce Gomes do Amaral, Paulo César Giraldo, Kleber Cursino, Ana Katherine Gonçalves, José Eleutério, Helena Giraldo Tags: Brief communications Source Type: journals

Estradiol improves genital herpes vaccine efficacy in mice.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Herpes Simplex Virus type 2 causes genital herpes but is frequently transmitted asymptomatically; therefore, a prophylactic vaccine is desirable. A candidate vaccine in clinical trials has only shown efficacy in preventing disease in women. Using this subunit vaccine candidate, we were able to demonstrate infection prophylaxis, improved disease prevention and modulated antibody production by complimenting vaccination with estradiol in our murine model. Findings of estradiol-enhanced vaccine efficacy are the first of their kind using a vaccine of this type and have potential clinical relevance to the development of othe...
Source: Vaccine - August 2, 2009 Category: Allergy & Immunology Authors: Pennock JW, Stegall R, Bell B, Vargas G, Motamedi M, Milligan G, Bourne N Tags: Vaccine Source Type: journals

Scientists learn why even treated genital herpes sores boost the risk of HIV infectionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(NIH/National Institute of Allergy and Infectious Diseases) New research helps explain why infection with herpes simplex virus-2 (HSV-2), which causes genital herpes, increases the risk for HIV infection even after successful treatment heals the genital skin sores and breaks that often result from HSV-2. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - August 2, 2009 Category: Global & Universal Source Type: news

STI rates rose by 0.5% last year, HPA figures showEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The number of gonorrhoea and syphilis infections in the UK has fallen, but cases of genital warts and herpes infections are up., the latest figures from the Health Protection Agency show. (Source: Pulse Today Clinical Updates)
Source: Pulse Today Clinical Updates - July 24, 2009 Category: Primary Care Tags: News Source Type: info

Gonorrhoea down as herpes risesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The number of gonorrhoea and syphilis infections in the UK falls - but genital warts and herpes are up. (Source: BBC News | Health | UK Edition)
Source: BBC News | Health | UK Edition - July 24, 2009 Category: Consumer Health News Tags: Health Source Type: news

Two cases of herpes zoster, occurring 4 and 6 weeks after the initiation of citalopram treatmentEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Two cases of herpes zoster which occurred 4 and 6 weeks after the beginning of citalopram antidepressant therapy are presented. A Medline search did not reveal any previous reports on herpes zoster associated with citalopram, or selective serotonin reuptake inhibitors (SSRIs) in general. In 1991, reported three cases of reactivated herpes simplex associated with fluoxetine treatment in depressive patients. In these cases, genital herpes was reactivated 4 weeks after beginning fluoxetine and labial herpes simplex 2 weeks after the initiation of fluoxetine. For the third case regarding recurrent genital herpes, no time da...
Source: Psychiatry Research - July 22, 2009 Category: Psychiatry Authors: Areti C. Spyropoulou Tags: Letters to the Editor Source Type: journals

Serologic and genotypic analysis of a series of herpes simplex virus type 1 isolates from two patients with genital herpesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Herpes simplex virus type 1 (HSV-1) has been reported increasingly as a cause of genital herpes, although HSV-1 is usually associated with oro-labial herpes. In the present study, serum specimens and materials for viral isolation were obtained serially from two patients with recrudescent HSV-1 genital infections to study serology and molecular epidemiology. Recurrent episodes, during which HSV-1 was isolated, were followed by an increase in the level of anti-HSV-1 antibody, suggesting a booster effect from re-exposure to viral antigens and the possible usefulness of the variation in the level of anti-HSV-1 antibody to diag...
Source: Journal of Medical Virology - July 21, 2009 Category: Virology Authors: Kenichi Umene, Takashi Kawana, Yasuyuki Fukumaki Tags: Research Article Source Type: journals

[Clinical] Recurrent lumbosacral herpes simplex in two menEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Two cases of recurrent lumbosacral herpes simplex without concomitant genital lesions are reported. Both patients presented with vesicular lesions on the middle of the lower back and on the left thigh, respectively, and had positive serum antibody to herpes simplex virus type 2 and negative antibody to HIV. The lesions healed completely within 1 week by oral administration of acyclovir. (Source: Sexually Transmitted Infections)
Source: Sexually Transmitted Infections - July 21, 2009 Category: Sexual Medicine Authors: Fan, Y-M, Yang, Y-P, Li, W Tags: Drugs: infectious diseases, HIV/AIDS, HIV / AIDS, Dermatology, HIV infections Clinical Source Type: journals

[Basic science] Use of the designation "shedder" in mucosal detection of herpes simplex virus DNA involving repeated samplingEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Most HSV-2 seropositive people shed HSV from the genital mucosa. Dichotomisation of people into "shedders" and "non-shedders" or "high" and "low" shedders yields inferences that depend upon sampling interval length. Overall shedding rates provide consistent measures regardless of the number of swabs collected. (Source: Sexually Transmitted Infections)
Source: Sexually Transmitted Infections - July 21, 2009 Category: Sexual Medicine Authors: Magaret, A S, Johnston, C, Wald, A Tags: Epidemiologic studies, Drugs: infectious diseases, HIV/AIDS, HIV / AIDS, HIV infections Basic science Source Type: journals

[Behaviour] Intent to accept and acceptance of herpes testing in adolescents and young adultsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: This study suggests that intent does not always predict behaviour, even when the two are measured within close temporal proximity. There are factors that may predict intent only or behaviour only, or may predict behaviour, but solely through influencing intent. Understanding how these various relationships work may be important to efforts designed to maximise acceptance of HSV-2 testing. (Source: Sexually Transmitted Infections)
Source: Sexually Transmitted Infections - July 21, 2009 Category: Sexual Medicine Authors: Kelly, N C, Zimet, G D, Aalsma, M C, Bernstein, D I, Fortenberry, J D, Rosenthal, S L Tags: herpes simplex virus Behaviour Source Type: journals

Researchers Said Using Condoms Reduced Risk Of Genital HerpesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Researchers who analyzed pooled data from several studies concluded that using condoms was linked to a modest reduction in the risk of acquiring the herpes simplex virus 2 (HSV-2), although the effect was not as large as that observed with other sexually transmitted diseases. The research was the work of lead author Emily T. (Source: Sexual Health / STDs News From Medical News Today)
Source: Sexual Health / STDs News From Medical News Today - July 15, 2009 Category: Sexual Medicine Tags: Sexual Health / STDs Source Type: news

Condoms reduce genital herpes riskEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
SEATTLE, July 14 (UPI) -- Condom use is associated with a 30 percent reduced risk of contracting herpes simplex virus 2, also known as genital herpes, U.S. researchers said. (Source: Health News - UPI.com)
Source: Health News - UPI.com - July 14, 2009 Category: Consumer Health News Source Type: news