Malaria Vaccine
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AIDS, UTI, Herpes Vaccines May Exist In 5 Years
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Malaria. Tuberculosis. Alzheimer's disease. AIDS. Pandemic flu. Genital herpes. Urinary tract infections. Grass allergies. Traveler's diarrhea. You name it, the pharmaceutical industry is working on a vaccine to prevent it. Many could be on the market in five years or less. Contrast that with five years ago, when so many companies had abandoned the vaccine business that half the U.S. supply of flu shots was lost because of factory contamination at one of the two manufacturers left. (Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire)
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - November 18, 2009 Category: Consumer Health News Source Type: consumer
Vaccines on horizon for Alzheimer's, herpes, AIDSEmail this article to a colleague.
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Malaria. Tuberculosis. Alzheimer's disease. AIDS. Pandemic flu. Genital herpes. Urinary tract infections. Grass allergies. Traveler's diarrhea. You name it, the pharmaceutical industry is working on a vaccine to prevent it. (Source: CTV Health)
Source: CTV Health - November 18, 2009 Category: Consumer Health News Source Type: news
Vaccines for AIDS, Alzheimer's, herpes on the horizonEmail this article to a colleague.
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Malaria. Tuberculosis. Alzheimer's disease. AIDS. Pandemic flu. Genital herpes. Urinary tract infections. Grass allergies. Traveler's diarrhea. You name it, the pharmaceutical industry is working on a vaccine to prevent it.
Many could be on the market in... (Source: OrlandoSentinel: Medical Research)
Source: OrlandoSentinel: Medical Research - November 18, 2009 Category: American Health Source Type: news
Identification of cultivation condition to produce correctly folded form of a malaria vaccine based on Plasmodium falciparum merozoite surface protein-1 in Escherichia coli.Email this article to a colleague.
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The C-terminal, 19-kDa domain of Plasmodium falciparum merozoite surface protein-1 (PfMSP-1(19)) is among the leading vaccine candidate for malaria due to its essential role in erythrocyte invasion by the parasite. We designed a synthetic gene for optimal expression of recombinant PfMSP-1(19) in Escherichia coli and developed a scalable process to obtain high-quality PfMSP-1(19). The synthetic gene construct yielded a fourfold higher expression level of PfMSP-1(19) in comparison to the native gene construct. Optimization of cultivation conditions in the bioreactor indicated important role of yeast extract and substrate...
Source: Bioprocess and Biosystems Engineering - November 18, 2009 Category: Biomedical Engineering Authors: Mazumdar S, Sachdeva S, Chauhan VS, Yazdani SS Tags: Bioprocess Biosyst Eng Source Type: journals
Vaccines On Horizon For AIDS, Alzheimer's, HerpesEmail this article to a colleague.
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Malaria. Tuberculosis. Alzheimer's disease. AIDS. Pandemic flu. Genital herpes. Urinary tract infections. Grass allergies. Traveler's diarrhea. You name it, the pharmaceutical industry is working on a vaccine to prevent it. (Source: WDSU.com - Health)
Source: WDSU.com - Health - November 17, 2009 Category: Consumer Health News Authors: WDSU.com Source Type: news
'Golden era' could bring vaccines against AIDS, Alzheimer's and addictions within 5 yearsEmail this article to a colleague.
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MARIETTA, Pa. (AP) — Malaria. Tuberculosis. Alzheimer's disease. AIDS. Pandemic flu. Genital herpes. Urinary tract infections. Grass allergies. Traveler's diarrhea. You name it, the pharmaceutical industry is working on a vaccine to prevent it.... (Source: OrlandoSentinel: Medical Research)
Source: OrlandoSentinel: Medical Research - November 17, 2009 Category: American Health Source Type: news
Origins of MalariaEmail this article to a colleague.
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Malaria has plagued people for thousands of years. And we have no way of preventing it via vaccine. But that may soon change. Virus hunter Nathan Wolfe believes he's solved the mystery of where malaria originated -- a discovery that could lead to a cure.
Sound Medicine's Dr. David Crabb talks with Nathan Wolfe about his research.
Wolf is a microbiologist and visiting professor at Stanford U.... (Source: Sound Medicine)
Source: Sound Medicine - November 15, 2009 Category: Global & Universal Authors: Sound Medicine Source Type: info
Uniting To Fight The World's Neglected DiseasesEmail this article to a colleague.
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Drug companies and nonprofit organizations are joining forces to develop new drugs and vaccines to target so-called "neglected" diseases that claim millions of lives in the developing world each year. Those hard-to-treat diseases include malaria, tuberculosis, dengue fever, and other conditions. That's the topic of the cover story scheduled for the current issue of Chemical & Engineering News, ACS' weekly newsmagazine. (Source: Tropical Diseases News From Medical News Today)
Source: Tropical Diseases News From Medical News Today - November 12, 2009 Category: Tropical Medicine Tags: Tropical Diseases Source Type: news
Uniting To Fight The World's Neglected DiseasesEmail this article to a colleague.
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Drug companies and nonprofit organizations are joining forces to develop new drugs and vaccines to target so-called "neglected" diseases that claim millions of lives in the developing world each year. Those hard-to-treat diseases include malaria, tuberculosis, dengue fever, and other conditions. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 12, 2009 Category: Consumer Health News Tags: Tropical Diseases Source Type: news
Parasite threshold associated with clinical malaria in areas of different transmission intensities in north eastern TanzaniaEmail this article to a colleague.
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Conclusions:
Dose response model with threshold parameter can be used to estimate parasite threshold associated with malaria fever onset. Parasite threshold were lower in older individuals and in low malaria transmission area. (Source: BMC Medical Research Methodology - Latest articles)
Source: BMC Medical Research Methodology - Latest articles - November 12, 2009 Category: Research Authors: Bruno MmbandoJohn LusinguLasse VestergaardMartha LemngeThor TheanderThomas Scheike Source Type: journals
Mathematical Model for Optimal Use of Sulfadoxine-Pyrimethamine as a Temporary Malaria Vaccine.Email this article to a colleague.
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In this paper, we introduce a deterministic malaria model for determining the drug administration protocol that leads to the smallest first malaria episodes during the wet season. To explore the effects of administering the malaria drug on different days during the wet season while minimizing the potential harmful effects of drug overdose, we define 40 drug administration protocols. Our results fit well with the clinical studies of Coulibaly et al. at a site in Mali. In addition, we provide protocols that lead to smaller number of first malaria episodes during the wet season than the protocol of Coulibaly et al.
PM...
Source: Bulletin of Mathematical Biology - November 12, 2009 Category: Bioinformatics Authors: Dembele B, Friedman A, Yakubu AA Tags: Bull Math Biol Source Type: journals
Drug industry, nonprofits join forces to fight world's neglected diseasesEmail this article to a colleague.
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(American Chemical Society) Drug companies and nonprofit organizations are joining forces to develop new drugs and vaccines to target so-called "neglected" diseases that claim millions of lives in the developing world each year. Those hard-to-treat diseases include malaria, tuberculosis, dengue fever and other conditions. That's the topic of the cover story scheduled for the current issue of Chemical & Engineering News, ACS' weekly newsmagazine. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 11, 2009 Category: Global & Universal Source Type: news
The wheat germ cell-free protein synthesis system: a key tool for novel malaria vaccine candidate discovery.Email this article to a colleague.
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Malaria kills more than a million people a year, causes malady in about three hundred million people and poses risk to approximately 40% of the world's population living in malarious countries. This disease is re-emerging mainly due to the development of drug-resistant parasites and insecticide-resistant mosquitoes. Therefore, we are now forced to resort to remedy through vaccination. Until now, not even a single licensed malaria vaccine has been developed despite intensive efforts. Even the efficacy of RTS,S, the most advanced and promising vaccine candidate in the pipeline of malaria vaccine development, was only aro...
Source: Acta Tropica - November 11, 2009 Category: Infectious Diseases Authors: Tsuboi T, Takeo S, Arumugam TU, Otsuki H, Torii M Tags: Acta Trop Source Type: journals
Africa: Hopes Rise for First Global Malaria VaccineEmail this article to a colleague.
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It has been revealed that after 20 years of trials, scientists are on the threshold of discovering a malaria vaccine. (Source: AllAfrica News: Malaria)
Source: AllAfrica News: Malaria - November 9, 2009 Category: Infectious Diseases Source Type: news
East Africa: Region to Take Part in Historic Malaria Vaccine TrialsEmail this article to a colleague.
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East Africa is among regions that have been put on a malaria vaccine trial as world scientists frantically seek a lasting solution to the world's leading killer disease. (Source: AllAfrica News: Malaria)
Source: AllAfrica News: Malaria - November 9, 2009 Category: Infectious Diseases Source Type: news
A glimpse into the clinical proteome of human malaria parasites Plasmodium falciparum and Plasmodium vivaxEmail this article to a colleague.
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Malaria causes a worldwide annual mortality of about a million people. Rapidly evolving drug-resistant species of the parasite have created a pressing need for the identification of new drug targets and vaccine candidates. By developing fractionation protocols to enrich parasites from low-parasitemia patient samples, we have carried out the first ever proteomics analysis of clinical isolates of early stages of Plasmodium falciparum (Pf) and P. vivax. Patient-derived malarial parasites were directly processed and analyzed using shotgun proteomics approach using high-sensitivity MS for protein identification. Our study revea...
Source: Proteomics. Clinical Applications - November 9, 2009 Category: Biochemistry Authors: Pragyan Acharya, Rani Pallavi, Syama Chandran, Harshini Chakravarti, Sheetal Middha, Jyoti Acharya, Sanjay Kochar, Dhanpat Kochar, Amit Subudhi, Arun P. Boopathi, Shilpi Garg, Ashis Das, Utpal Tatu Tags: Research Articles Source Type: journals
High hopes for a malaria vaccineEmail this article to a colleague.
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The makers of Mosquirix announce a trial involving thousands of children in Africa. They aim to seek marketing approval as soon as 2012 and have a vaccine that reduces infections by 80% by 2025.
Each year, malaria kills more than 1 million people -- 90% of them in sub-Saharan Africa and 80% of them younger than 5 -- and makes 300 million people seriously ill. Major progress in controlling the disease has been made by the widespread adoption of bed nets to keep mosquitoes from attacking children at night and by the use of artemisinin-based therapy, which is the most effective t...
Source: Los Angeles Times - Science - November 7, 2009 Category: Science Source Type: news
Antigenics Provides Details On GlaxoSmithKline's Pivotal Malaria Vaccine Trial With QS-21 AdjuvantEmail this article to a colleague.
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Antigenics, Inc. (NASDAQ: AGEN) today indicated that GlaxoSmithKline's (GSK) Phase III malaria vaccine clinical trial, containing Antigenics' QS-21 Stimulon® adjuvant, has enrolled more than 5,000 children to date and is expected to involve up to 16,000 children. The pivotal efficacy study of RTS,S, the world's most clinically advanced malaria vaccine, is ongoing in seven African countries. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 6, 2009 Category: Consumer Health News Tags: Tropical Diseases Source Type: news
Antigenics Provides Details On GlaxoSmithKline's Pivotal Malaria Vaccine Trial With QS-21 AdjuvantEmail this article to a colleague.
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Antigenics, Inc. (NASDAQ: AGEN) today indicated that GlaxoSmithKline's (GSK) Phase III malaria vaccine clinical trial, containing Antigenics' QS-21 Stimulon® adjuvant, has enrolled more than 5,000 children to date and is expected to involve up to 16,000 children. The pivotal efficacy study of RTS,S, the world's most clinically advanced malaria vaccine, is ongoing in seven African countries. (Source: Immune System / Vaccines News From Medical News Today)
Source: Immune System / Vaccines News From Medical News Today - November 6, 2009 Category: Allergy & Immunology Tags: Tropical Diseases Source Type: news
Malaria vaccine strategy aims for eradicationEmail this article to a colleague.
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The PATH Malaria Vaccine Initiative has outlined its ambitions for the next generation of vaccines. (Source: SciDev.Net)
Source: SciDev.Net - November 6, 2009 Category: Global & Universal Source Type: info
Will Promising New Malaria Vaccine Deliver?Email this article to a colleague.
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Among challenges ahead- administering the vaccine in Africa's most remote areas. (Source: ABC News: Health)
Source: ABC News: Health - November 5, 2009 Category: Consumer Health News Source Type: news
AFRICA: Malaria Vaccine Draws CloserEmail this article to a colleague.
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NAIROBI, Nov 4 (IPS) - After 20 years of trials, scientists have announced
they are on the threshold of discovering a malaria vaccine.
Researchers warn that Africa may not be ready to make use of the
vaccine should it be approved as expected within five years. (Source: IPS Inter Press Service - Preventable Diseases Africa)
Source: IPS Inter Press Service - Preventable Diseases Africa - November 5, 2009 Category: African Health Source Type: info
GSK start new malaria vaccine trialEmail this article to a colleague.
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GlaxoSmithKline has launched the next phase of its malaria vaccine trial in seven African countries (Source: Pharmacy Europe)
Source: Pharmacy Europe - November 5, 2009 Category: Drugs & Pharmacology Source Type: news
AMFm Subsidized Malaria Drugs To Be Delivered SoonEmail this article to a colleague.
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Subsidized artemisinin-based combination therapies (ACTs) under the Affordable Medicines Facility - malaria (AMFm) program will be available in select countries "in two week's time," (Source: Immune System / Vaccines News From Medical News Today)
Source: Immune System / Vaccines News From Medical News Today - November 5, 2009 Category: Allergy & Immunology Tags: Tropical Diseases Source Type: news
Africa: Malaria Vaccine Draws CloserEmail this article to a colleague.
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After 20 years of trials, scientists have announced they are on the threshold of discovering a malaria vaccine. Researchers warn that Africa may not be ready to make use of the vaccine should it be approved as expected within five years. (Source: AllAfrica News: Malaria)
Source: AllAfrica News: Malaria - November 5, 2009 Category: Infectious Diseases Source Type: news
News Outlets Examine First World Pneumonia DayEmail this article to a colleague.
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To mark the first World Pneumonia Day, Inter Press Service examines how vaccines and other strategies can be used to combat the disease, which kills more children under age 5 each year "than measles, malaria, and AIDS combined, according to the Global Coalition against Child Pneumonia. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 4, 2009 Category: Consumer Health News Tags: Infectious Diseases / Bacteria / Viruses Source Type: news
Malaria Conference Addresses RTS,S Vaccine, Tools, TreatmentEmail this article to a colleague.
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On Tuesday at the 5th Multilateral Initiative on Malaria (MIM) Pan-African Conference in Nairobi, Kenya, scientists and global health experts focused on malaria eradication, Agence France-Presse reports. "Key among the strategies ... is the development of an effective anti-malaria vaccine, a project scientists have been researching since the late 80s. ... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 4, 2009 Category: Consumer Health News Tags: Tropical Diseases Source Type: news
Africa: Continent to Benefit From World's Largest Malaria Vaccine TrialEmail this article to a colleague.
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A pivotal efficacy trial of RTS,S, the world's most clinically advanced malaria vaccine candidate, is now underway in seven African countries: Burkina Faso, Gabon, Ghana, Kenya, Malawi, Mozambique and Tanzania, a statement made available to Leadership Correspondent in New York has said. (Source: AllAfrica News: Malaria)
Source: AllAfrica News: Malaria - November 4, 2009 Category: Infectious Diseases Source Type: news
World's Largest Malaria Vaccine Trial Now Underway In 7 African CountriesEmail this article to a colleague.
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A pivotal efficacy trial of RTS,S, the world's most clinically advanced malaria vaccine candidate, is now underway in seven African countries: Burkina Faso, Gabon, Ghana, Kenya, Malawi, Mozambique and Tanzania. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 4, 2009 Category: Consumer Health News Tags: Tropical Diseases Source Type: news
World largest malaria vaccine trial underway in AfricaEmail this article to a colleague.
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By Daniel Ooko
NAIROBI, Nov. 4 (Xinhua) -- A pivotal ... (Source: Xinhuanet Chinaview Health)
Source: Xinhuanet Chinaview Health - November 4, 2009 Category: Consumer Health News Tags: Health Source Type: news
World's Largest Malaria Vaccine Trial Now Underway In Seven African CountriesEmail this article to a colleague.
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A pivotal efficacy trial of RTS,S, the world's most clinically advanced malaria vaccine candidate, is now underway in seven African countries: Burkina Faso, Gabon, Ghana, Kenya, Malawi, Mozambique and Tanzania. The trial, which is expected to involve up to 16,000 children, is on schedule, with more than 5,000 children already enrolled, researchers announced. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - November 4, 2009 Category: Science Source Type: news
World's largest malaria vaccine trial now underway in seven African countriesEmail this article to a colleague.
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A pivotal efficacy trial of RTS,S, the world's most clinically advanced malaria vaccine candidate, is now underway in seven African countries: Burkina Faso, Gabon, Ghana, Kenya, Malawi, Mozambique and Tanzania. The trial, which is expected to involve up to 16,000 children, is on schedule, with more than 5,000 children already enrolled, researchers announced Tuesday at the 5th Multilateral Initiative on Malaria Pan-African Malaria Conference. (Source: World Pharma News)
Source: World Pharma News - November 4, 2009 Category: Pharmaceuticals Source Type: news
Vaccine Could Boost Africa's Malaria FightEmail this article to a colleague.
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With Production at Least 3 Years Away, Tests Show Treatment Could Save Thousands of Children (Source: Health News: CBSNews.com)
Source: Health News: CBSNews.com - November 3, 2009 Category: Consumer Health News Source Type: news
New vaccine offers hope in Africa's malaria battleEmail this article to a colleague.
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A mother watched with dread as a nurse inserted a tube in her baby's head. Blood streamed into the anemic 4-month-old who already has malaria, the mosquito-borne disease that kills a million African children every year. (Source: CTV Health)
Source: CTV Health - November 3, 2009 Category: Consumer Health News Source Type: news
PATH Malaria Vaccine Initiative Shares Strategy For Developing 'Next-Generation' Malaria VaccinesEmail this article to a colleague.
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Marking its tenth anniversary year, the PATH Malaria Vaccine Initiative (MVI) unveiled a new strategy that sets the stage for an aggressive push targeting the long-term goal of eliminating and eradicating malaria. Malaria is one of the world's deadliest infectious diseases, killing nearly 900,000 people a year, most of them children in sub-Saharan Africa. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 3, 2009 Category: Consumer Health News Tags: Tropical Diseases Source Type: news
Kenya: Africa Not Ready for Malaria Vaccine, Says ResearcherEmail this article to a colleague.
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African countries are not prepared to receive the malaria vaccine yet, a scientist said on Tuesday. (Source: AllAfrica News: Malaria)
Source: AllAfrica News: Malaria - November 3, 2009 Category: Infectious Diseases Source Type: news
New Malaria Vaccine Offers Hope for KidsEmail this article to a colleague.
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The vaccine could save half a million African children each year. (Source: ABC News: Health)
Source: ABC News: Health - November 3, 2009 Category: Consumer Health News Source Type: news
Malaria Conference Begins In Nairobi, Will Highlight Outlook For RTS,S Experimental Malaria VaccineEmail this article to a colleague.
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The 5th Multilateral Initiative on Malaria (MIM) Pan-African Conference "kicked off in Nairobi late Sunday with a call for substantial and sustained support for research to guide evidence-based policies and the development of new malaria tools, which together could save countless lives," Xinhua reports (11/2). (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 3, 2009 Category: Consumer Health News Tags: Tropical Diseases Source Type: news
World's largest Malaria Vaccine Trial Now Underway In Seven African CountriesEmail this article to a colleague.
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A pivotal efficacy trial of RTS,S, the world's most clinically advanced malaria vaccine candidate, is now underway in seven African countries: Burkina Faso, Gabon, Ghana, Kenya, Malawi, Mozambique and Tanzania. (Source: Pharmaceutical Online News)
Source: Pharmaceutical Online News - November 3, 2009 Category: Pharmaceuticals Source Type: news
World's largest malaria vaccine trial now underway in 7 African countriesEmail this article to a colleague.
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(PATH Malaria Vaccine Initiative) A pivotal efficacy trial of RTS,S, the world's most clinically advanced malaria vaccine candidate, is now underway in seven African countries: Burkina Faso, Gabon, Ghana, Kenya, Malawi, Mozambique and Tanzania. The trial, which is expected to involve up to 16,000 children, is on schedule, with more than 5,000 children already enrolled, researchers announced Tuesday at the 5th Multilateral Initiative on Malaria Pan-African Malaria Conference. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - November 3, 2009 Category: Global & Universal Source Type: news
Malaria vax Phase III underwayEmail this article to a colleague.
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Developers of the most advanced malaria vaccine candidate to date are shooting for approval in 2012 (Source: The Scientist)
Source: The Scientist - November 3, 2009 Category: Science Authors: Jef Akst Source Type: info
Pneumonia: Vaccination Essential To Prevent World's Leading Child KillerEmail this article to a colleague.
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Marking the first international World Pneumonia Day on 2 November, the GAVI Alliance plans to immunise 130 million children in poor countries against pneumonia, the world's leading child killer. Pneumonia, a severe inflammation of the lungs usually caused by infection, is responsible for one in four child deaths, more than HIV/AIDs, malaria and measles combined. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 2, 2009 Category: Consumer Health News Tags: Respiratory / Asthma Source Type: news
PATH Malaria Vaccine Initiative shares strategy for developing 'next-generation' malaria vaccinesEmail this article to a colleague.
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(PATH Malaria Vaccine Initiative) Marking its tenth anniversary year, the PATH Malaria Vaccine Initiative today unveiled a new strategy that sets the stage for an aggressive push targeting the long-term goal of eliminating and eradicating malaria. Malaria is one of the world's deadliest infectious diseases, killing nearly 900,000 people a year, most of them children in sub-Saharan Africa. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - November 2, 2009 Category: Biology Source Type: news
Malaria talks focus on vaccineEmail this article to a colleague.
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About 1,500 health experts have opened six days of talks in Nairobi to discuss research in the fight against malaria, including work on a new experimental vaccine. (Source: CBC | Health)
Source: CBC | Health - November 1, 2009 Category: Consumer Health News Source Type: news
Successful sporozoite challenge model in human volunteers with Plasmodium vivax strain derived from human donors.Email this article to a colleague.
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In conclusion, malaria-naive volunteers can be safely and reproducibly infected with bites of 2-10 An. albimanus mosquitoes carrying P. vivax sporozoites. This challenge method is suitable for vaccine and anti-malarial drug testing.
PMID: 19861603 [PubMed - in process] (Source: The American Journal of Tropical Medicine and Hygiene)
Source: The American Journal of Tropical Medicine and Hygiene - October 31, 2009 Category: Tropical Medicine Authors: Herrera S, Fernández O, Manzano MR, Murrain B, Vergara J, Blanco P, Palacios R, Vélez JD, Epstein JE, Chen-Mok M, Reed ZH, Arévalo-Herrera M Tags: Am J Trop Med Hyg Source Type: journals
The Potential Role of Vaccines in the Elimination of Falciparum Malaria and the Eventual Eradication of MalariaEmail this article to a colleague.
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The Journal of Infectious Diseases, Volume 0, Issue 0, Page 000, Latest Articles. (Source: The Journal of Infectious Diseases Latest Issue)
Source: The Journal of Infectious Diseases Latest Issue - October 30, 2009 Category: Infectious Diseases Tags: article PERSPECTIVE Source Type: journals
GSK Will Ensure Experimental Malaria Vaccine Is Affordable, CEO SaysEmail this article to a colleague.
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GlaxoSmithKline CEO Andrew Witty said Wednesday the company would ensure that if an experimental malaria vaccine works, it would be priced reasonably, Reuters reports. "The vaccine, called (Source: Immune System / Vaccines News From Medical News Today)
Source: Immune System / Vaccines News From Medical News Today - October 30, 2009 Category: Allergy & Immunology Tags: Tropical Diseases Source Type: news
