Rotavirus Vaccine
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Rotavirus W179-9 vaccine: Diarrhoea in an infant with severe combined immune deficiency: case report
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(Source: Reactions)
Source: Reactions - November 16, 2009 Category: Drugs & Pharmacology Tags: Short communication Source Type: journals
Global Health: Defeating Rotavirus? The Global Recommendation for Rotavirus Vaccination
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This past April, the World Health Organization (WHO) Strategic Advisory Group of Experts (SAGE) on Immunization announced a global recommendation that rotavirus vaccines be included in national immunization programs. The ... (Source: New England Journal of Medicine)
Source: New England Journal of Medicine - November 11, 2009 Category: Internal Medicine Authors: Danchin, M. H., Bines, J. E. Tags: PERSPECTIVE Source Type: journals
Infant Rotavirus Vaccine Reduced Diarrhea-Related Hospitalizations, ED Visits, and Outpatient Visits
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The pentavalent rotavirus vaccine is safe and effective and greatly reduces resource use and expenditures related to diarrheal illness in infants younger than 1 year of age. Medscape Medical News (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - November 7, 2009 Category: Consumer Health News Tags: Infectious Diseases Source Type: news
Infant Rotavirus Vaccine Reduces Diarrhea-Related Hospitalizations, ED Visits, and Outpatient Visits
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The pentavalent rotavirus vaccine is safe and effective and greatly reduces resource use and expenditures related to diarrheal illness in infants younger than 1 year of age. Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - November 7, 2009 Category: Consumer Health News Tags: Infectious Diseases Source Type: news
Compelling Rotavirus Burden Data And Critical Need For Access To Vaccines In High-Burden Regions Outlined In Journal Of Infectious Diseases
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The Journal of Infectious Diseases has released a special edition, Global Rotavirus Surveillance: Preparing for the Introduction of Rotavirus Vaccines. This special edition provides a significant contribution to the understanding of rotavirus disease burden and the impact of rotavirus vaccines, which have the potential to save an estimated 228,000 lives annually. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 7, 2009 Category: Consumer Health News Tags: Infectious Diseases / Bacteria / Viruses Source Type: news
Compelling Rotavirus Burden Data And Critical Need For Access To Vaccines In High-Burden Regions Outlined In Journal Of Infectious Diseases
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The Journal of Infectious Diseases has released a special edition, Global Rotavirus Surveillance: Preparing for the Introduction of Rotavirus Vaccines. This special edition provides a significant contribution to the understanding of rotavirus disease burden and the impact of rotavirus vaccines, which have the potential to save an estimated 228,000 lives annually. (Source: Immune System / Vaccines News From Medical News Today)
Source: Immune System / Vaccines News From Medical News Today - November 7, 2009 Category: Allergy & Immunology Tags: Infectious Diseases / Bacteria / Viruses Source Type: news
Rotavirus vaccine needed in more countries
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NEW YORK, Nov. 6 (UPI) -- Rotavirus vaccines could save an estimated 228,000 lives worldwide each year by reducing deadly diarrhea, the World Health Organization said. (Source: Health News - UPI.com)
Source: Health News - UPI.com - November 6, 2009 Category: Consumer Health News Source Type: news
Journal special edition outlines rotavirus burden and need for vaccines
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(PATH) The Journal of Infectious Diseases has released a special edition, Global Rotavirus Surveillance: Preparing for the Introduction of Rotavirus Vaccines. This special edition provides a significant contribution to the understanding of rotavirus disease burden and the impact of rotavirus vaccines, which have the potential to save an estimated 228,000 lives annually. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - November 5, 2009 Category: Biology Source Type: news
Viral gastroenteritis
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Abstract: The virology, immunology, diagnosis, clinical symptoms, treatment, epidemiology and prevention measures relating to the most common viral causes of acute gastroenteritis (rotaviruses, human caliciviruses, astroviruses and enteric adenoviruses) are briefly reviewed. Uncommon viral causes of acute gastroenteritis and viruses causing gastroenteritis in immunodeficient patients are mentioned. The main change over the past three years has been the development, licensing and wide application of new live attenuated rotavirus vaccines. (Source: Medicine)
Source: Medicine - November 1, 2009 Category: Internal Medicine Authors: Ulrich Desselberger, Jim Gray Tags: Gastrointestinal infections Source Type: journals
Profit Driven Swine Flu Propaganda - Pump Up the Volume - Part Five
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This article is part five in a six-part series. Be sure to read part four at http://www.naturalnews.com/027336_swine_flu_health_propaganda.htmlIn the video commentary titled, Mild Swine Flu and Over-Hyped Vaccine, on the website for the National Vaccine Information Center, the group's co-founder and president, Barbara Loe Fisher, reports: "We are witnessing a roll-out of the largest, most expensive mass vaccination campaign in the history of our nation. A rollout that is bigger than even the polio vaccine campaigns of the 1950's.""If you or your child are injured from getting a flu swine flu shot, you are on your own," Fis...
Source: NaturalNews.com - October 30, 2009 Category: Consumer Health Advice Source Type: news
Rotarix (Rotavirus Vaccine, Live, Oral Suspension) - updated on RxList
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Rotarix (Rotavirus Vaccine, Live, Oral Suspension) drug description - FDA approved labeling for prescription drugs and medications at RxList (Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - October 30, 2009 Category: Drugs & Pharmacology Source Type: consumer
Adoption of Rotavirus Vaccination by Pediatricians and Family Medicine Physicians in the United States
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CONCLUSIONS: Rates of offering the new rotavirus vaccine are high among pediatricians but <50% among family medicine physicians. Both specialties identified financial barriers to use of the vaccine, but family medicine physicians had significantly more concerns about safety and about adding another vaccine to the vaccination schedule. (Source: PEDIATRICS)
Source: PEDIATRICS - October 26, 2009 Category: Pediatrics Authors: Kempe, A., Patel, M. M., Daley, M. F., Crane, L. A., Beaty, B., Stokley, S., Barrow, J., Babbel, C., Dickinson, L. M., Tempte, J. L., Parashar, U. D. Tags: Infectious Disease & Immunity ARTICLES Source Type: journals
Rapid changes in rotaviral genotypes in Ecuador
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Previous studies suggest that the emerging G9P[8] genotype was the most prevalent rotavirus genotype in Ecuador during 2005. This present study provides a temporal analysis of the distribution of rotavirus genotypes in two locations within Ecuador by adding additional years (2006 - early 2008) to the originally reported 2005 data. Data were collected in a rural (northern coastal Ecuador) and urban (Quito) area. In the rural area, a community sample of cases (those presenting diarrhea) and controls (those not presenting diarrhea) were collected between August 2003 and March 2008 resulting in a total of 3,300 stool samples (...
Source: Journal of Medical Virology - October 25, 2009 Category: Virology Authors: Maria Eloisa Hasing, Gabriel Trueba, Maria Ines Baquero, Karina Ponce, William Cevallos, Owen D. Solberg, Joseph N.S. Eisenberg Tags: Research Article Source Type: journals
Reduction in Rotavirus Infection Since Vaccine Introduction
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(Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - October 23, 2009 Category: Primary Care Tags: Medical News Source Type: info
Rotavirus Vaccine Cutting Infection Rates Among Kids
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Title: Rotavirus Vaccine Cutting Infection Rates Among KidsCategory: Health NewsCreated: 10/22/2009 12:10:00 PMLast Editorial Review: 10/23/2009 (Source: MedicineNet Crohn's Disease General)
Source: MedicineNet Crohn's Disease General - October 23, 2009 Category: Gastroenterology Source Type: consumer
Rotavirus Vaccine Cutting Infection Rates Among Kids
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Title: Rotavirus Vaccine Cutting Infection Rates Among KidsCategory: Health NewsCreated: 10/22/2009 12:10:00 PMLast Editorial Review: 10/23/2009 (Source: MedicineNet Senior Health General)
Source: MedicineNet Senior Health General - October 23, 2009 Category: Geriatrics Source Type: consumer
eduction in Rotavirus After Vaccine Introduction --- United States, 2000--2009.
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Authors:
Worldwide, rotavirus is the leading cause of severe acute diarrhea in children aged <5 years. In the United States, before introduction of a live, oral pentavalent rotavirus vaccine (RV5) in 2006, rotavirus caused an estimated 20 to 60 deaths, 55,000 to 70,000 hospitalizations, 205,000 to 272,000 emergency department visits, and 410,000 outpatient visits annually. Before 2000, rotavirus had a predictable winter-spring seasonality and geographic pattern in the United States, with activity beginning in the West census region during December--January, extending across the country, and ending in the Northeast...
Source: MMWR Morb Mortal Wkl... - October 23, 2009 Category: Epidemiology Tags: MMWR Morb Mortal Wkly Rep Source Type: journals
Reduction in rotavirus after vaccine introduction--United States, 2000-2009.
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Authors:
Worldwide, rotavirus is the leading cause of severe acute diarrhea in children aged <5 years. In the United States, before introduction of a live, oral pentavalent rotavirus vaccine (RV5) in 2006, rotavirus caused an estimated 20 to 60 deaths, 55,000 to 70,000 hospitalizations, 205,000 to 272,000 emergency department visits, and 410,000 outpatient visits annually. Before 2000, rotavirus had a predictable winter-spring seasonality and geographic pattern in the United States, with activity beginning in the West census region during December-January, extending across the country, and ending in the Northeast ...
Source: MMWR Morb Mortal Wkl... - October 23, 2009 Category: Epidemiology Tags: MMWR Morb Mortal Wkly Rep Source Type: journals
CDC: Vaccine reduces rotavirus in children
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ATLANTA, Oct. 22 (UPI) -- Rotavirus -- severe acute diarrhea in young children -- fell substantially after introduction of a vaccine to combat it, U.S. health officials say. (Source: Health News - UPI.com)
Source: Health News - UPI.com - October 22, 2009 Category: Consumer Health News Source Type: news
Vaccine Reduces Rotavirus Season
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Since the 2006 introduction of a vaccine, the rotavirus season in the U.S. has started later and ended sooner, the CDC reported. (Source: MedPage Today Infectious Disease)
Source: MedPage Today Infectious Disease - October 22, 2009 Category: Infectious Diseases Source Type: news
Rotavirus Vaccine Cutting Infection Rates Among Kids
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CDC report shows drop in U.S. incidence since vaccine was introduced in 2006 Source: HealthDay
Related MedlinePlus Topics: Childhood Immunization, Rotavirus Infections (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - October 22, 2009 Category: Consumer Health News Source Type: consumer
Effect of prophylactic paracetamol administration at time of vaccination on febrile reactions and antibody responses in children
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Source: Lancet
Area: News
Two consecutive (primary and booster) open-label RCTs have assessed the effect of prophylactic administration of paracetamol at vaccination on infant febrile reaction rates and vaccine responses.
The study enrolled 459 healthy infants from ten centres in the Czech Republic who were randomised to receive three prophylactic paracetamol doses every 6 to 8 hours in the first 24 hours (n=226) or no prophylactic paracetamol (n=233) after each vaccination.
[Vaccines= ten-valent pneumococcal non-typeable Haemophilus influenzae protein D-conjugate vaccine (PHiD-CV) co-administered wi...
Source: NeLM - Immunology and vaccination - October 15, 2009 Category: Allergy & Immunology Source Type: organizations
Grant For Anti-Diarrhea Vaccine Study In Nicaragua Awarded To UNC Researcher
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A University of North Carolina at Chapel Hill researcher has been awarded a four-year, $507,000 grant from the National Institutes of Health's Fogarty International Center to study the effectiveness of rotavirus vaccines in the Central American nation of Nicaragua. The grant was awarded to Sylvia Becker-Dreps, M.D., M.P.H. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - October 15, 2009 Category: Consumer Health News Tags: GastroIntestinal / Gastroenterology Source Type: news
UNC researcher awarded grant for anti-diarrhea vaccine study in Nicaragua
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(University of North Carolina School of Medicine) A University of North Carolina at Chapel Hill researcher has been awarded a four-year, $507,000 grant from the National Institute of Health's Fogarty International Center to study the effectiveness of rotavirus vaccines in the Central American nation of Nicaragua. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - October 13, 2009 Category: Global & Universal Source Type: news
Burden of disease and circulating serotypes of rotavirus infection in sub-Saharan Africa: systematic review and meta-analysis.
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Title: Burden of disease and circulating serotypes of rotavirus infection in sub-Saharan Africa: systematic review and meta-analysis.Authors: Sanchez-Padilla, Elisabeth; Grais, Rebecca F; Guerin, Philippe J; Steele, Andrew D; Burny, Marie-Eve; Luquero, Francisco JAbstract: Two new rotavirus vaccines have recently been licensed in many countries. However, their efficacy has only been shown against certain serotypes commonly circulating in Europe, North America, and Latin America, but thought to be globally important. To assess the potential impact of these vaccines in sub-Saharan Africa, where rotavirus mortality is high, k...
Source: MSF Field Research - October 7, 2009 Category: Global & Universal Authors: search Source Type: journals
Mass rotavirus vaccination, a cost-effective strategy in India
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(Source: PharmacoEconomics and Outcomes News)
Source: PharmacoEconomics and Outcomes News - October 5, 2009 Category: Health Management Tags: Research article Source Type: journals
[Predominance of G9 rotavirus in Valencia and Castellón between 2005 and 2007.]
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CONCLUSIONS: Rotavirus G9P[8] have spread rapidly and widely during the 2005-2006 and 2006-2007 seasons, replacing other previously dominant genotypes (G1, G4) in our geographic area. Its incidence has declined sharply in 2007-2008, in which G1P[8] was again the predominating genotype.
PMID: 19811963 [PubMed - as supplied by publisher] (Source: Anales de Pediatria)
Source: Anales de Pediatria - October 4, 2009 Category: Pediatrics Authors: Téllez Castillo CJ, Montava Vilaplana R, Fernández Jiménez M, Ribes Fernández JM, Buesa Gómez J Tags: An Pediatr (Barc) Source Type: journals
Retrospective surveillance for intussusception in children aged less than five years in a South Indian tertiary-care hospital.
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This study provides baseline data on intussusception in South India. Cases identified in the study were similar in presentation and demographics as those observed in other Asian settings. Prospective surveillance systems, using standardized case definitions will further increase the understanding of the aetiology and epidemiology of intussusception, especially as new rotavirus vaccines are made available.
PMID: 19902802 [PubMed - in process] (Source: Journal of Health, Population, and Nutrition)
Source: Journal of Health, Population, and Nutrition - October 1, 2009 Category: Global & Universal Authors: Bhowmick K, Kang G, Bose A, Chacko J, Boudville I, Datta SK, Bock HL Tags: J Health Popul Nutr Source Type: journals
The burden of rotavirus hospitalizations among medicaid and non-medicaid children younger than 5 years old.
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CONCLUSIONS: Although RGE affects all socioeconomic groups, the Medicaid population accounted for a disproportionate number of the hospitalizations. With the inclusion of rotavirus vaccines in the pediatric immunization schedule, it is important that US children, especially those enrolled in Medicaid programs, are vaccinated to reduce the burden of RGE.
PMID: 19797754 [PubMed - in process] (Source: American Journal of Public Health)
Source: American Journal of Public Health - September 30, 2009 Category: Global & Universal Authors: Ma L, El Khoury AC, Itzler RF Tags: Am J Public Health Source Type: journals
International Medica Foundation Starts Phase II Clinical Trial For Rotavirus Vaccine
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More than half a million children - or 1,400 to 1,600 each day - die from rotavirus, the most common cause of severe childhood diarrhea. Almost all of these deaths occur in developing countries, where lifesaving medical care may not be affordable or available to the families with the most critical needs. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - September 30, 2009 Category: Consumer Health News Tags: Immune System / vaccines Source Type: news
Molecular characterization of a rare, human-porcine reassortant rotavirus strain, G11P[6], from Ecuador
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Abstract The Pan-American Health Organization established a rotavirus pre-vaccination disease burden and strain surveillance network
in Latin America and the Caribbean in 2004. During strain surveillance in Ecuador in 2005–2006, a rare rotavirus genotype,
G11P[6], was detected among common strains. Sequencing and phylogenetic analysis of this strain identified a novel lineage
of the G11 VP7 gene, most closely related to A253 (91.8% nt identity), a porcine rotavirus strain identified in Venezuela.
Most genes of this strain clustered with porcine, human-porcine or bovine-porcine reassortant strains; only VP6...
Source: Archives of Virology - September 18, 2009 Category: Virology Tags: Archives of Virology Source Type: journals
Finland introduces rotavirus vaccine into the national vaccination programme in September 2009.
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Supported by an economic evaluation, rotavirus vaccine is introduced into the national immunisation schedule in Finland. The vaccination programme has been estimated to be reasonably cost-effective. Given at the age of two, three and five months, the vaccine is expected to prevent annually in Finland among children under the age of five years approximately 2,000 rotavirus diarrhoea episodes needing hospitalisation, and over 10,000 outpatient visits. The impact of the programme will be evaluated in 2011 by repeating the economic analysis and carefully monitoring adverse events.
PMID: 19728979 [PubMed - in process] (...
Source: Euro Surveill - September 6, 2009 Category: Infectious Diseases Authors: Nohynek H, Salo H, Renko M, Leino T Tags: Euro Surveill Source Type: journals
Burden of rotavirus gastroenteritis and potential benefits of a pentavalent rotavirus vaccination in Belgium
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A structured abstract written by CRD reviewers. The abstract was published on 19 August 2009 from an original article published in 2008. (Source: Gastroenterology and Liver Diseases Specialist Library - Stomach)
Source: Gastroenterology and Liver Diseases Specialist Library - Stomach - September 4, 2009 Category: Gastroenterology Source Type: organizations
Burden of rotavirus gastroenteritis and potential benefits of a pentavalent rotavirus vaccination in Belgium
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A structured abstract written by CRD reviewers. The abstract was published on 19 August 2009 from an original article published in 2008. (Source: Gastroenterology and Liver Diseases Specialist Library - Small intestine)
Source: Gastroenterology and Liver Diseases Specialist Library - Small intestine - September 4, 2009 Category: Gastroenterology Source Type: organizations
Guidelines for the Prevention and Treatment of Opportunistic Infections among HIV-exposed and HIV-infected children: recommendations from CDC, the National Institutes of Health, the HIV Medicine Association of the Infectious Diseases Society of America, the Pediatric Infectious Diseases Society, and the American Academy of Pediatrics.
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This report updates and combines into one document earlier versions of guidelines for preventing and treating opportunistic infections (OIs) among HIV-exposed and HIV-infected children, last published in 2002 and 2004, respectively. These guidelines are intended for use by clinicians and other health-care workers providing medical care for HIV-exposed and HIV-infected children in the United States. The guidelines discuss opportunistic pathogens that occur in the United States and one that might be acquired during international travel (i.e., malaria). Topic areas covered for each OI include a brief description of the epidem...
Source: MMWR Recomm Rep - September 3, 2009 Category: Epidemiology Authors: Mofenson LM, Brady MT, Danner SP, Dominguez KL, Hazra R, Handelsman E, Havens P, Nesheim S, Read JS, Serchuck L, Van Dyke R, , , , , Tags: MMWR Recomm Rep Source Type: journals
Finland introduces rotavirus vaccine into the national vaccination programme in September 2009
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Supported by an economic evaluation, rotavirus vaccine is introduced into the national immunisation schedule in Finland. The vaccination programme has been estimated to be reasonably cost-effective. Given at the age of two, three and five months, the vaccine is expected to prevent annually in Finland among children under the age of five years approximately 2,000 rotavirus diarrhoea episodes needing hospitalisation, and over 10,000 outpatient visits. The impact of the programme will be evaluated in 2011 by repeating the economic analysis and carefully monitoring adverse events. (Source: Eurosurveillance latest news)
Source: Eurosurveillance latest news - September 3, 2009 Category: Infectious Diseases Source Type: journals
Severity of acute gastroenteritis in infants infected by G1 or G9 rotaviruses
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Conclusions: No difference in severity was found between G1 and G9 rotavirus infections. Rigorous surveillance to monitor changes in the ecology of rotavirus infections is necessary, as emerging strains are more likely to cause severe gastroenteritis and not respond to current rotavirus vaccines. (Source: Journal of Clinical Virology)
Source: Journal of Clinical Virology - September 1, 2009 Category: Virology Authors: Camille Aupiais, Alexis de Rougemont, Cédric Menager, Christelle Vallet, Jean-François Brasme, Jérôme Kaplon, Pierre Pothier, Dominique Gendrel Tags: Short communications Source Type: journals
Genetic characterization of rotavirus subtypes in Pakistan-first report of G12 genotype from Pakistan under WHO-Eastern Mediterranean region.
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Rotaviruses are among the major causes of gastroenteritis and diarrhea among children in developed as well as the developing countries. The rapidly evolving strain prevalence and circulation have resulted in the emergence of novel strains over the period worldwide. The introduction of G12 prototype in 1987 from Philippines and subsequently re-emergence among most of the Asian countries along with USA and Europe has provoked new research horizons to address the global distribution of rotavirus serotypes. These newly emerging subtypes and their sustenance among the population have posed tremendous challenge to the develo...
Source: Virus Research - August 31, 2009 Category: Virology Authors: Alam MM, Malik SA, Shaukat S, Naeem A, Sharif S, Angez M, Rana MS, Khurshid A, Zaidi SZ Tags: Virus Res Source Type: journals
Rotavirus-associated intussusception followed by spontaneous resolution.
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Rotavirus was related to causing intussusception when the first generation rotavirus vaccine was introduced. However, the association between natural rotavirus infection and intussusception remains an area of concern and controversy. A few studies have found that rotavirus infection can cause intussusception. On the other hand, several studies were unable to find an association of intussusception with natural rotavirus infection. Herein, we describe a patient who developed intussusception following rotavirus diarrhea during the course of hospitalization and recovered by spontaneous resolution the next day. This rotavir...
Source: The Turkish Journal of Gastroenterology - August 31, 2009 Category: Gastroenterology Authors: Dallar Y, Bostanci I, Bozdayi G, Doğan B, Başbay Y, Battaloğlu NO, Rota S, Nishizono A, Ahmed K Tags: Turk J Gastroenterol Source Type: journals
Kenya: Rotavirus Vaccine Can Save Millions
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Every year, millions of African children do not live to see their fifth birthday due to illnesses such as pneumonia and diarrhoea, which are among the top causes of childhood deaths. We cannot make any strides in child health without addressing these two illnesses. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - August 31, 2009 Category: African Health Source Type: news
Health Experts Appeal For Vaccines To Be Added To National Immunization Programs
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During a recent three-day Asian Vaccine Conference, health experts appealed to countries to add "under-utilised vaccines such as those of pneumococcal, haemophilus influenzae type-b (Hib), and rotavirus" into national immunization programs, the Nation reports. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - August 31, 2009 Category: Consumer Health News Tags: Immune System / vaccines Source Type: news
MMWR Publishes Early Release of the Updated Guidelines for the Prevention and Treatment of Opportunistic Infection in HIV-Exposed and HIV-Infected Children
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“New guidelines to assist health care workers in preventing and treating the secondary infections that can afflict U.S. children exposed to, or infected with, HIV, were published by the National Institutes of Health and the Centers for Disease Control and Prevention....
“Major changes in the pediatric guidelines include:
Emphasis on the importance of effective antiretroviral therapy to improve children’s immune function.…
Information on diagnosing and managing immune reconstitution inflammatory syndrome….
Information on the management of antiretroviral therapy in children with opportunistic infections, in...
Source: AIDSinfo At-a-Glance: Offering Information on HIV/AIDS Treatment, Prevention, and Research, A Service of the U.S. Department of Health and Human Services (DHHS) - August 27, 2009 Category: Infectious Diseases Source Type: info
Rotavirus vaccine 'safe for under twos'
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A vaccine against severe rotavirus gastroenteritis is safe and effective if used during the first two years of life, according to a study by researchers from Singapore and China. (Source: Pulse Today Clinical Updates)
Source: Pulse Today Clinical Updates - August 27, 2009 Category: Primary Care Tags: News Source Type: info
New vaccines for developing countries: will it be feast or famine?
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The Revolving Fund of the Pan American Health Organization (PAHO) has an almost 30 year track record of providing access to essential vaccines for the entire population of Latin America and the Caribbean region. The activities of the PAHO Revolving Fund, coupled with the provision of high-quality technical assistance, were crucial to the successful control, elimination, or eradication of most of the region's great childhood killers, including measles and polio. Today, however, the Revolving Fund faces new challenges in the form of procuring a new generation of vaccines for human papillomavirus infection, rotavirus, and...
Source: American Journal of Law and Medicine - August 26, 2009 Category: Medical Law Authors: Andrus JK, de Quadros C, Matus CR, Luciani S, Hotez P Tags: Am J Law Med Source Type: journals
The cost-effectiveness of rotavirus vaccination: Comparative analyses for five European countries and transferability in Europe.
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Cost-effectiveness analyses are usually not directly comparable between countries because of differences in analytical and modelling assumptions. We investigated the cost-effectiveness of rotavirus vaccination in five European Union countries (Belgium, England and Wales, Finland, France and the Netherlands) using a single model, burden of disease estimates supplied by national public health agencies and a subset of common assumptions. Under base case assumptions (vaccination with Rotarix((R)), 3% discount rate, health care provider perspective, no herd immunity and quality of life of one caregiver affected by a rotavir...
Source: Vaccine - August 24, 2009 Category: Allergy & Immunology Authors: Jit M, Bilcke J, Mangen MJ, Salo H, Melliez H, Edmunds WJ, Yazdan Y, Beutels P Tags: vaccine Source Type: journals
South Africa: New Effort to Curb Child Mortality
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Government has added a new vaccine to fight mortality among children under five. The Rotavirus Vaccine, aimed at preventing diarrheal diseases, is the latest addition to the country's Expanded Program of Immunisation (EPI). (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - August 24, 2009 Category: African Health Source Type: news
Rotavirus Strategies to evade host antiviral innate immunity.
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Virus infection initiates the host antiviral innate immune response. Paradoxically, viruses can adopt several strategies to evade or subvert host innate immunity to ensure their survival. This mechanism is a significant consideration in the development of an attenuated vaccine and in the basic research of host-virus interaction. Rotavirus is the main cause of gastroenteritis in infants, and leads to approximately 500,000 deaths annually, mainly in developing countries. The strategies that the rotavirus adopts to evade host antiviral innate immunity are summarized in this review.
PMID: 19712697 [PubMed - as supplied...
Source: Immunology Letters - August 23, 2009 Category: Allergy & Immunology Authors: Liu K, Yang X, Wu Y, Li J Tags: Immunol Lett Source Type: journals
Rotavirus Vaccine Induced Diarrhea In Child With Severe Combined Immune Deficiency
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An article appearing in The Journal of Allergy and Clinical Immunology (JACI) examines the first reported case of persistent shedding of the rotavirus vaccine in a patient with severe combined immune deficiency (SCID). The authors report a case of a 9-month-old infant girl who was examined in the hospital after a history of faltering growth and chronic diarrhea. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - August 23, 2009 Category: Consumer Health News Tags: Infectious Diseases / Bacteria / Viruses Source Type: news
Efficacy of Rotavirus Vaccine RV5 against Severe and Very Severe Diarrhea in Nicaraguan Children
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(Source: AccessMedicine Updates)
Source: AccessMedicine Updates - August 21, 2009 Category: Internal Medicine Source Type: info
Clinical laboratory practices for the detection of rotavirus in England and Wales: can surveillance based on routine laboratory testing data be used to evaluate the impact of vaccination?
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Two rotavirus vaccines have recently been licensed in Europe. Rotavirus surveillance data in many European countries are based on reports of laboratory-confirmed rotavirus infections. If surveillance data based on routine laboratory testing data are to be used to evaluate the impact of vaccination programmes, it is important to determine how the data are influenced by differences in testing practices, and how these practices are likely to affect the ability of the surveillance data to represent trends in rotavirus disease in the community. We conducted a survey of laboratory testing policies for rotavirus gastroenterit...
Source: Euro Surveill - August 20, 2009 Category: Infectious Diseases Authors: Atchison CJ, Lopman BA, Harris CJ, Tam CC, Iturriza Gómara M, Gray JJ Tags: Euro Surveill Source Type: journals
