Tetanus VaccineThis is an RSS file. You can use it to subscribe to this data in your favourite RSS reader, such as GoogleReader, or to display this data on your own website or blog. Subscribe to this data using MyMedWorm.Subscribe to this data using GoogleReader.Subscribe to this data using Bloglines.Subscribe to this data using MyYahoo.

This page shows you your search results in order of date.

674 records returned

GAVI Alliance Drives Down Pentavalent Vaccine Costs, Data ShowsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The "co-ordinated buying policy" of the GAVI Alliance has driven down "[t]he price of a vaccine that helps babies fight off killer diseases," according to data released by the group, Reuters reports. In 2010, the price of pentavalent vaccine, which protects against Hib (Haemophilus influenzae type b), diphtheria, whooping cough, tetanus and hepatitis B, will fall "below $3.0 - a drop of almost $0. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 19, 2009 Category: Consumer Health News Tags: Immune System / vaccines Source Type: news

GAVI Alliance Drives Down Pentavalent Vaccine Costs, Data ShowsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The "co-ordinated buying policy" of the GAVI Alliance has driven down "[t]he price of a vaccine that helps babies fight off killer diseases," according to data released by the group, Reuters reports. In 2010, the price of pentavalent vaccine, which protects against Hib (Haemophilus influenzae type b), diphtheria, whooping cough, tetanus and hepatitis B, will fall "below $3.0 - a drop of almost $0. (Source: Immune System / Vaccines News From Medical News Today)
Source: Immune System / Vaccines News From Medical News Today - November 19, 2009 Category: Allergy & Immunology Tags: Immune System / vaccines Source Type: news

[Newsdesk] Childhood vaccination and progress towards MDG4Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Agencies and individuals worldwide are continuing their efforts to vaccinate the world's children and their achievements are highlighted by State of the World's Vaccines and Immunization, a major report published recently by WHO, UNICEF, and The World Bank. “We have good news…”, announced Daisy Mafubelu, Assistant Director General of Family and Community Health at WHO (Geneva, Switzerland). “The number of children being vaccinated is now at an all time high—and we have the numbers to prove this.” In 2008, 106 million children received routine vaccinations for childhood killer infectious diseases including measl...
Source: The Lancet Infectious Diseases - November 16, 2009 Category: Infectious Diseases Authors: Kathryn Senior Tags: Newsdesk Source Type: journals

KINRIX (Diphtheria And Tetanus Toxoids And Acellular Pertussis Adsorbed And Inactivated Poliovirus Vaccine) Injection, Suspension [GlaxoSmithKline Biologicals SA]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Updated Date: Nov 13, 2009 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))
Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) - November 13, 2009 Category: Drugs & Pharmacology Source Type: organizations

BOOSTRIX (Tetanus Toxoid, Reduced Diphtheria Toxoid And Acellular Pertussis Vaccine, Adsorbed) Suspension [GlaxoSmithKline Biologicals SA]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Updated Date: Nov 13, 2009 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))
Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) - November 13, 2009 Category: Drugs & Pharmacology Source Type: organizations

PEDIARIX (Diphtheria And Tetanus Toxoids And Acellular Pertussis Adsorbed, Hepatitis B (Recombinant) And Inactivated Poliovirus Vaccine Combined) Injection, Suspension [GlaxoSmithKline Biologicals SA]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Updated Date: Nov 12, 2009 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))
Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) - November 12, 2009 Category: Drugs & Pharmacology Source Type: organizations

Effect of Granulocyte/Macrophage Colony-Stimulating Factor on Circulating CD8+ and CD4+ T-Cell Responses to a Multipeptide Melanoma Vaccine: Outcome of a Multicenter Randomized Trial.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: High immune response rates for this multipeptide vaccine were achieved, but CD8(+) and CD4(+) T-cell responses were lower when administered with GM-CSF. These data challenge the value of local GM-CSF as a vaccine adjuvant in humans. (Clin Cancer Res 2009;15(22):7036-44). PMID: 19903780 [PubMed - as supplied by publisher] (Source: Cell Research)
Source: Cell Research - November 10, 2009 Category: Cytology Authors: Slingluff CL, Petroni GR, Olson WC, Smolkin ME, Ross MI, Haas NB, Grosh WW, Boisvert ME, Kirkwood JM, Chianese-Bullock KA Tags: Clin Cancer Res Source Type: journals

Pattern of functional antibody activity against Haemophilus influenzae type b (Hib) in infants immunized with diphtheria-tetanus-pertussis/Hib Brazilian combination vaccine.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We evaluated the functional activity of Haemophilus influenzae B (Hib) antibodies elicited in a group of infants immunized with the diphtheria-tetanus-pertussis vaccine combined with an Hib vaccine produced totally in Brazil after technological transfer of Hib vaccine production from Glaxo SmithKline, Belgium. Blood samples from immunized infants (N = 985) were collected for the determination of Hib antibodies. Total Ig and IgM and IgG subclasses of antibodies against polyribosyl ribitol phosphate (PRP) were analyzed by ELISA. Almost all vaccinees (97.56%, 961/985) developed a strong anti-PRP IgG antibody response (>...
Source: Braz J Med Biol Res - November 6, 2009 Category: Research Authors: Matos DC, Silva AM, Neves PC, Martins RM, Homma A, Marcovistz R Tags: Braz J Med Biol Res Source Type: journals

INFANRIX (Diphtheria And Tetanus Toxoids And Acellular Pertussis Vaccine Adsorbed) Suspension [GlaxoSmithKline Biologicals SA]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Updated Date: Nov 3, 2009 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))
Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) - November 3, 2009 Category: Drugs & Pharmacology Source Type: organizations

Uptake of meningococcal conjugate vaccine among adolescents in large managed care organizations, United States, 2005: Demand, supply and seasonality.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Background: In February 2005, the US Advisory Committee on Immunization Practices recommended the new meningococcal conjugate vaccine (MCV4) for routine use among 11- to 12-year-olds (at the preadolescent health-care visit), 14- to 15-year-olds (before high-school entry), and groups at increased risk. Vaccine distribution started in March; however, in July, the manufacturer reported inability to meet demand and widespread MCV4 shortages were reported. Our objectives were to determine early uptake patterns among target (11-12 and 14-15 year olds) and non-target (13- plus 16-year-olds) age groups. A post hoc analysis was con...
Source: BMC Infectious Diseases - November 3, 2009 Category: Infectious Diseases Authors: Suchita LorickDaniel FishbeinEric WeintraubPascale WortleyGrace LeeFangjun ZhouRobert Davis Source Type: journals

Vaccines as a trigger for myopathies.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Vaccines are considered to be among the greatest medical discoveries, credited with the virtual eradication of some diseases and the consequent improved survival and quality of life of the at-risk population. With that, vaccines are among the environmental factors implicated as triggers for the development of inflammatory myopathies. The sporadic reports on vaccine-induced inflammatory myopathies include cases of hepatitis B virus, bacillus Calmette-Guérin, tetanus, influenza, smallpox, polio, diphtheria, diphtheria-pertussis-tetanus, combination of diphtheria with scarlet fever and diphtheria-pertussis-tetanus wi...
Source: Lupus - November 1, 2009 Category: Rheumatology Authors: Orbach H, Tanay A Tags: Lupus Source Type: journals

Transverse myelitis and vaccines: a multi-analysis.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Transverse myelitis is a rare clinical syndrome in which an immune-mediated process causes neural injury to the spinal cord. The pathogenesis of transverse myelitis is mostly of an autoimmune nature, triggered by various environmental factors, including vaccination. Our aim here was to search for and analyze reported cases of transverse myelitis following vaccination. A systematic review of PubMed, EMBASE and DynaMed for all English-language journals published between 1970 and 2009 was preformed, utilizing the key words transverse myelitis, myelitis, vaccines, post-vaccination, vaccination and autoimmunity. We have dis...
Source: Lupus - November 1, 2009 Category: Rheumatology Authors: Agmon-Levin N, Kivity S, Szyper-Kravitz M, Shoenfeld Y Tags: Lupus Source Type: journals

Daptacel (Diphtheria and Tetanus Toxoids and Acellular Pertussis Vaccine Adsorbed) - updated on RxListEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Daptacel (Diphtheria and Tetanus Toxoids and Acellular Pertussis Vaccine Adsorbed) drug description - FDA approved labeling for prescription drugs and medications at RxList (Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - October 30, 2009 Category: Drugs & Pharmacology Source Type: consumer

Pediarix (Diphtheria, Tetanus Toxoids and Acellular Pertussis Adsorbed, Hepatitis B and Inactivated Poliovirus Vaccine) - updated on RxListEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Pediarix (Diphtheria, Tetanus Toxoids and Acellular Pertussis Adsorbed, Hepatitis B and Inactivated Poliovirus Vaccine) drug description - FDA approved labeling for prescription drugs and medications at RxList (Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - October 29, 2009 Category: Drugs & Pharmacology Source Type: consumer

Philippines: Ongoing aid to the most vulnerable almost a month after violent tropical stormsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In Manila and surrounding areas, tens of thousands of people are still living in very critical conditions in crowded evacuation centres or partially flooded houses, following the devastation of the storms that hit four and three weeks ago. These living conditions expose the population to waterborne and contagious diseases and close medical follow-up is critical. In the slums near a canal east of Manila and in all affected areas of Laguna Bay, MSF has been running mobile primary healthcare clinics with referrals to local hospitals. “The most frequent diseases we see are respiratory and skin infections as well as dia...
Source: MSF News - October 23, 2009 Category: Global & Universal Tags: NEWS Source Type: organizations

Also notedEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This study examines whether the pain response to administration of the diphtheria, polio, and tetanus toxoids and acellular pertussis and Haemophilus influenzae type b vaccine and the pneumococcal conjugate vaccine is affected by the order in which they are given. With the validated Modified Behavioral Pain Scale, videotaped recordings of the procedure (to assess crying), and parental ratings of pain on a visual analog scale, they found that children had less pain (on all 3 measures) when the diphtheria, polio, and tetanus toxoids and acellular pertussis and diphtheria, polio, and tetanus toxoids and acellular pertussis an...
Source: The Journal of Pediatrics - October 20, 2009 Category: Pediatrics Tags: Current Best Evidence Source Type: journals

[Reflection and Reaction] Has routine immunisation in Africa become endangered?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The broad picture of immunisation in Africa is one of excellent progress and enthusiastic energy, with amazing advances having been made since the turn of the century. There has been a large drop in mortality due to measles, and about a third of countries now use a three dose regimen of diphtheria-tetanus-pertussis triple vaccine (DTP3), which provides coverage of at least 80% in all districts. However, a review of immunisation in Africa found that all is not well. (Source: The Lancet Infectious Diseases)
Source: The Lancet Infectious Diseases - October 18, 2009 Category: Infectious Diseases Authors: Yemane Berhane, C John Clements, Jean Michel Ndiaye, Patricia Taylor Tags: Reflection and Reaction Source Type: journals

[Vaccination and multiple sclerosis.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Vaccinations to prevent communicable diseases are, like in other chronic diseases, of special importance in patients with multiple sclerosis (MS). Various bacterial and viral infections have been shown to induce relapses of MS. Reports of possible adverse effects of vaccinations on the course of multiple sclerosis have led patients and treating physicians to exercise caution in the use of vaccines. A number of vaccines have been studied with respect to the risk in MS patients. Some vaccines, for example against yellow fever, are not indicated in MS due to the risk of MS exacerbation. In contrast, tetanus or hepatitis B...
Source: Der Nervenarzt - October 16, 2009 Category: Neurology Authors: Löbermann M, Winkelmann A, Reisinger EC, Zettl UK Tags: Nervenarzt Source Type: journals

Paracetamol affects childhood jabsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Giving paracetamol to babies following a vaccine jab may lower the effectiveness of the immunisation, according to research reported on by BBC news. The study behind this news coverage is an important and well-conducted trial in which 459 babies receiving their routine immunisations were either routinely given paracetamol in the 24 hours following their injection or were given none. Although the drug was clearly successful in reducing the risk of a fever developing, it was shown to reduce the immune response to the vaccine, suggesting that it would be less effective. Although the preventative use of paracetamol had an ef...
Source: NHS News Feed - October 16, 2009 Category: Consumer Health News Tags: Pregnancy/child Medication Source Type: news

Effect of prophylactic paracetamol administration at time of vaccination on febrile reactions and antibody responses in childrenEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Source: Lancet Area: News Two consecutive (primary and booster) open-label RCTs have assessed the effect of prophylactic administration of paracetamol at vaccination on infant febrile reaction rates and vaccine responses. The study enrolled 459 healthy infants from ten centres in the Czech Republic who were randomised to receive three prophylactic paracetamol doses every 6 to 8 hours in the first 24 hours (n=226) or no prophylactic paracetamol (n=233) after each vaccination. [Vaccines= ten-valent pneumococcal non-typeable Haemophilus influenzae protein D-conjugate vaccine (PHiD-CV) co-administered wi...
Source: NeLM - Immunology and vaccination - October 15, 2009 Category: Allergy & Immunology Source Type: organizations

Physical interventions and injection techniques for reducing injection pain during routine childhood immunizations: systematic review of randomized controlled trials and quasi-randomized controlled trials.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: Pain during immunization can be decreased by: (1) injecting the least painful formulation of a vaccine; (2) having the child sit up (or holding an infant); (3) stroking the skin or applying pressure close to the injection site before and during injection; (4) injecting the least painful vaccine first when 2 vaccines are being administered sequentially during a single office visit; and (5) performing a rapid intramuscular injection without aspiration. PMID: 19781436 [PubMed - in process] (Source: Clinical Therapeutics)
Source: Clinical Therapeutics - October 14, 2009 Category: Drugs & Pharmacology Authors: Taddio A, Ilersich AL, Ipp M, Kikuta A, Shah V, Tags: Clin Ther Source Type: journals

Woman Blames Tetanus, Flu Shots For IllnessEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A woman recovering from encephalitis claims her illness was caused by vaccines. (Source: WDSU.com - Health)
Source: WDSU.com - Health - October 14, 2009 Category: Consumer Health News Authors: WDSU.com Source Type: news

Historical Data Shows Vaccines are Not what Saved UsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(NaturalNews) With all of the hype surrounding the H1N1 swine flu virus lately, everyone is very concerned with the safety and effectiveness of vaccines, and rightly so. This is a very important question that we must all ask ourselves and find out what the truth is. As the debate rages on an even more important question has rarely been asked. Do vaccines even protect you from the viruses and illnesses that they claim to?If you only get your news and information from mainstream news and educational sources, then the question about whether vaccines are effective is never even raised. This lack of discussion give the percepti...
Source: NaturalNews.com - October 9, 2009 Category: Consumer Health Advice Source Type: news

Diphtheria tetanus and pertussis vaccine: Recurrent hypotonic-hyporesponsive episodes in an infant: case reportEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Reactions)
Source: Reactions - October 6, 2009 Category: Drugs & Pharmacology Tags: Short communication Source Type: journals

What is the Appropriate Treatment for a Pedal Puncture Wound?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Discussion Ciprofloxacin and other fluoroquinolones have demonstrated cartilage and joint toxicity when administered to immature laboratory animals. Therefore health care providers have been reluctant to use fluoroquinolones in young children and voluntarily have avoided them. However in 2002, more than 182,000 courses of fluoroquinolones were administered to children. Research data is limited but the pediatric safety profile appears to be similar to the adult safety profile. Current indications for fluoroquinolones include complicated urinary tract infections, treatment of opportunistic infections in immunocompromised pat...
Source: PediatricEducation.org - October 5, 2009 Category: Pediatrics Authors: Donna M. D'Alessandro, M.D. Tags: Uncategorized Source Type: info

Frequency of medically attended adverse events following tetanus and diphtheria toxoid vaccine in adolescents and young adults: a Vaccine Safety Datalink studyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Medically attended local reactions were uncommon following Td vaccination. The risk of those reactions varied by age and by prior receipt of TDCVs. These findings provide a point of reference for future evaluations of the safety profile of newer vaccines containing tetanus or diphtheria toxoid. (Source: BMC Infectious Diseases)
Source: BMC Infectious Diseases - October 4, 2009 Category: Infectious Diseases Authors: Lisa JacksonOnchee YuEdward BelongiaSimon HambidgeJennifer NelsonRoger BaxterAllison NalewayCharlene GayJames NordinJames BaggsJohn Iskander Source Type: journals

Comparison of five commercial anti-tetanus toxoid IgG ELISAs: Diagnostic and clinical interpretations.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Five commercially available enzyme-linked immunosorbant assays (ELISAs) for the measurement of anti-tetanus toxoid IgG antibodies were evaluated for performance. The data suggests that there are manufacturer dependent differences in sensitivity and accuracy for the determination of tetanus toxoid IgG antibodies that could result in different diagnostic interpretations. PMID: 19793897 [PubMed - as supplied by publisher] (Source: Clinical and Vaccine Immunology)
Source: Clinical and Vaccine Immunology - September 29, 2009 Category: Allergy & Immunology Authors: Perry AL, Hayes AJ, Cox HA, Alcock F, Parker AR Tags: Clin vaccine Immunol Source Type: journals

Long-term presence of memory B-cells specific for different vaccine components.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In this study we describe the identification of antigen-specific memory B-cells in peripheral blood of persons born between 1940 and 2004 in The Netherlands. Polyclonal stimulation of either PBMCs or purified B-cells induced proliferation and differentiation of B-cells of the memory phenotype (CD19(+)/CD27(+)) into antibody secreting cells (ASC). Memory B-cells against components of bacterial vaccines (Bordetella pertussis and tetanus) as well as viral vaccines (measles and influenza) were thus identified, even in persons with low serum antibody titers. Enrichment of B-cells increased the sensitivity of memory B-cell detec...
Source: Vaccine - September 28, 2009 Category: Allergy & Immunology Authors: Buisman AM, de Rond CG, Oztürk K, Ten Hulscher HI, van Binnendijk RS Tags: vaccine Source Type: journals

AAFP Expands Pertussis Vaccination Awareness CampaignEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Almost three-quarters of U.S. adults think they are up-to-date on their immunizations, says a recent AAFP survey. According to CDC statistics, however, only 2 percent of adults received the tetanus toxoid, reduced diphtheria toxoid and acellular pertussis vaccine, or Tdap, from 2005 through 2007. (Source: AAFP Health of the Public)
Source: AAFP Health of the Public - September 25, 2009 Category: Primary Care Source Type: news

Cervarix (human papillomavirus vaccine) - Revised SPCEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Source: eMC (electronic Medicines Compendium) Area: Other Library Updates > SPC Changes New information has been included in section 4.5 (interactions) which is as follows: Use with other vaccines Cervarix may be administered concomitantly with a combined booster vaccine containing diphtheria (d), tetanus (T) and pertussis [acellular] (pa) with or without inactivated poliomyelitis (IPV), (dTpa, dTpa-IPV vaccines), with no clinically relevant interference with antibody response to any of the components of either vaccine. The sequential administration of combined dTpa-IPV followed by Cervarix one month later tended to e...
Source: NeLM - Immunology and vaccination - September 19, 2009 Category: Allergy & Immunology Source Type: organizations

Licensure of a Haemophilus influenzae type b (Hib) vaccine (Hiberix) and updated recommendations for use of Hib vaccine.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This report summarizes the indications for Hiberix use and provides guidance on Hib booster dose administration based on increasing vaccine supplies. Vaccination recommendations in this report update the previous advisory on Hib booster administration (June 26, 2009), which advised that children with deferred booster doses receive it at the next regularly scheduled visit. Vaccination providers are now recommended to begin recall of children in need of the booster dose when feasible and monovalent Hib vaccine supply in the office is adequate. PMID: 19763078 [PubMed - indexed for MEDLINE] (Source: MMWR Morb Mortal Wkl...)
Source: MMWR Morb Mortal Wkl... - September 17, 2009 Category: Epidemiology Tags: MMWR Morb Mortal Wkly Rep Source Type: journals

National, state, and local area vaccination coverage among adolescents aged 13-17 years--United States, 2008.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This report summarizes results from the 2008 NIS-Teen and, for the first time, includes estimates for each of the 50 states and selected local areas. Nationally, vaccination coverage for the three most recently recommended adolescent vaccinations and one childhood vaccination increased from 2007 to 2008: MCV4 (from 32.4% to 41.8%), Tdap (from 30.4% to 40.8%), >/=1 dose of HPV4 (from 25.1% to 37.2%), and >/=2 doses of VAR among those without disease history (from 18.8% to 34.1%). However, substantial variability in vaccination coverage was observed in 2008 among state and local areas and by race/ethnicity and poverty ...
Source: MMWR Morb Mortal Wkl... - September 17, 2009 Category: Epidemiology Tags: MMWR Morb Mortal Wkly Rep Source Type: journals

Vaccine Adherence in AdolescentsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This article outlines barriers to vaccine compliance among adolescents and discusses strategies to increase vaccine uptake. (Source: Clinical Pediatrics)
Source: Clinical Pediatrics - September 16, 2009 Category: Pediatrics Authors: Lehmann, C., Benson, P. A. S. Tags: Articles Source Type: journals

Risk of immune hemolytic anemia in children following immunization.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We examined the risk of IHA in the 42 days following vaccination exposure using a self-controlled case series study design. In our population-based cohort of nearly 4.5 million children in the Vaccine Safety Datalink, we identified 55 confirmed cases of new-onset IHA from 1991 through 2000. We found no association between IHA and diphtheria-pertussis-tetanus vaccination (incidence rate ratio (IRR)=0.65, 95% CI: 0.19-2.24), hepatitis B vaccination (IRR=1.73, 95% CI: 0.59-5.01), or any vaccination (IRR=1.04, 95% CI: 0.46-2.32). PMID: 19766577 [PubMed - as supplied by publisher] (Source: Vaccine)
Source: Vaccine - September 16, 2009 Category: Allergy & Immunology Authors: Naleway AL, Belongia EA, Donahue JG, Kieke BA, Glanz JM, Tags: vaccine Source Type: journals

Modified intra-cerebral challenge assay for acellular pertussis vaccines: Comparisons among whole cell and acellular vaccines.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This study thus suggests that an aP vaccine standard would improve inter-laboratory agreement. These data do not show significant dissimilarity in dose-response lines between JNIH-3 and the various vaccine products included, irrespective of the differences in aP components. Available data indicate that JNIH-3 is sufficiently stable to serve as an International Standard. On the basis of these results and with the agreement of the participants, it was proposed that JNIH-3 should be established as an International Standard for acellular pertussis vaccine for use in the modified intra-cerebral challenge assay and other protect...
Source: Vaccine - September 14, 2009 Category: Allergy & Immunology Authors: Gaines-Das R, Horiuchi Y, Zhang SM, Newland P, Kim Y, Corbel M, Xing D Tags: vaccine Source Type: journals

KINRIX (Diphtheria And Tetanus Toxoids And Acellular Pertussis Adsorbed And Inactivated Poliovirus Vaccine) Injection, Suspension [GlaxoSmithKline Biologicals SA]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Updated Date: Sep 14, 2009 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))
Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) - September 14, 2009 Category: Drugs & Pharmacology Source Type: organizations

Medical and Nursing Students with Suboptimal Protective Immunity against Vaccine‐Preventable Diseases • Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions. We have determined that there is a certain proportion of healthcare students who are susceptible to certain vaccine‐preventable diseases. The development of an appropriate vaccination strategy is required to decrease the risk of transmission in a hospital setting. (Source: Infect Control Hosp Epidemiol Latest Issue)
Source: Infect Control Hosp Epidemiol Latest Issue - September 10, 2009 Category: Epidemiology Tags: article Original Article Source Type: journals

Antibody Response to Polysaccharide Conjugate Vaccines after Nonmyeloablative Allogeneic Stem Cell TransplantationEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In this study, the reconstitution of humoral immunity after allo-RIST is determined by measuring the vaccination-induced antibody response against Streptococcus pneumoniae, Haemophilus influenzae type b (Hib), and tetanus toxoid (TT) 1 year posttransplantation. Patients who underwent allo-RIST were vaccinated according to a schedule starting at 12 months following transplantation with conjugated vaccines against S. pneumoniae, Hib, and TT. Of twenty-six patients both pre- and postvaccination sera were available. Patients were required to be off immunosuppression at the time of vaccination, and, therefore, 9 of the 26 patie...
Source: Biology of Blood and Marrow Transplantation - September 10, 2009 Category: Hematology Authors: Aafke Meerveld-Eggink, Ankie M.T. van der Velden, Gert J. Ossenkoppele, Arjan A. van de Loosdrecht, Douwe H. Biesma, Ger T. Rijkers Tags: Clinical Research Source Type: journals

[Current vaccination coverage and immunization gaps of children and adolescents in Germany.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Available data show increasing vaccination coverage of children and adolescents in recent years in Germany. Vaccination coverage of children against diphtheria, tetanus, polio and haemophilus influenzae Type b is high. Vaccination gaps exist for pertussis, hepatitis B and for the second measles, mumps and rubella doses. Coverage is still insufficient to achieve effective herd immunity and measles elimination. Data from the representative German Health Interview and Examination Survey for Children and Adolescents reveal that vaccination of infants is markedly delayed compared to recommendations of the German Standing Co...
Source: Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz - September 9, 2009 Category: Global & Universal Authors: Reiter S, Poethko-Müller C Tags: Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz Source Type: journals

Pertussis Immunity and Response to Tetanus-Reduced Diphtheria-Reduced Pertussis Vaccine (Tdap) after Autologous Peripheral Blood Stem Cell TransplantationEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Pertussis is a highly contagious respiratory infection characterized by prolonged cough and inspiratory whoop. Despite widespread vaccination of children aged2-fold response to PT following vaccination with Tdap. These data suggest that autologous transplantation recipients are highly susceptible to pertussis and that immunization with 2.5μg of PT induces an inadequate response. Prospective trials evaluating BOOSTRIX, containing 8μg/dose of PT (approved for adults in December 2008) are warranted in this vulnerable population undergoing transplantation. (Source: Biology of Blood and Marrow Transplantation)
Source: Biology of Blood and Marrow Transplantation - September 7, 2009 Category: Hematology Authors: Trudy N. Small, Andrew D. Zelenetz, Ariela Noy, R. David Rice, Tanya M. Trippett, Lauren Abrey, Carol S. Portlock, Emily J. McCullagh, Jill M. Vanak, Ann Marie Mulligan, Craig H. Moskowitz Tags: Clinical Research Source Type: journals

Shantha Biotechnics Awarded Large Vaccine Contracts by United Nations AgencyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Sanofi Pasteur, the vaccines division of sanofi-aventis Group (EURONEXT : SAN and NYSE : SNY), announced that Shantha Biotechnics was awarded contracts by a United Nations agency for supplies of pentavalent vaccine SHAN5™ (combination vaccine of Diphtheria, Pertussis, Tetanus, Haemophilus influenza B, and Hepatitis B). The contracts, worth $340 million, cover the period 2010-2012. (Source: World Pharma News)
Source: World Pharma News - September 6, 2009 Category: Pharmaceuticals Source Type: news

Levels of childhood vaccination coverage and the impact of maternal HIV status on child vaccination status in rural KwaZulu-Natal, South Africa*Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion Positive maternal HIV status independently reduces children's probability to receive child vaccinations, which likely contributes to the morbidity and mortality differential between children of HIV-positive and HIV-negative mothers. As a means of increasing vaccination coverage, policy makers should consider increasing the number of mobile clinics in this and similar communities in rural Africa. (Source: Tropical Medicine and International Health)
Source: Tropical Medicine and International Health - September 6, 2009 Category: Tropical Medicine Authors: James Ndirangu, Till Bärnighausen, Frank Tanser, Khin Tint, Marie-Louise Newell Source Type: journals

Pneumococcal Polysaccharide Protein D-Conjugate Vaccine (Synflorix; PHiD-CV).Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
black triangle The pneumococcal polysaccharide protein D-conjugate vaccine (PHiD-CV; Synflorix) contains ten capsular polysaccharide serotypes from the bacterium Streptococcus pneumoniae, eight of which are conjugated to a nonlipidated cell-surface liporotein (protein D) of non-typeable Haemophilus influenzae (NTHi) and two of which are conjugated to either tetanus or diphtheria toxoid. black triangle In a three-dose primary vaccination schedule in infants aged <6 months, PHiD-CV elicited high immune responses against all pneumococcal serotypes contained in the vaccine and was noninferior to an approved 7-valent pne...
Source: Paediatric Drugs - September 4, 2009 Category: Pediatrics Authors: Croxtall JD, Keating GM Tags: Paediatr Drugs Source Type: journals

NHS immunisation statistics England 2008-09Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Source: NHS Information Centre Area: News The NHS Information Centre has published immunisation statistics for England 2008-09; the key findings are as follows: . Over 87% of 12-13 year old girls (school year 8) received the first dose and 70% completing the programme of all 3 doses of HPV immunisation. . 78% of children received first and second doses of MMR vaccine between the ages of 2 and 5, a 4% increase on the previous year's figure; although London remains below the national average. . Uptake of vaccines against diphtheria, tetanus, polio, pertussis, Haemophilus influ...
Source: NeLM - Immunology and vaccination - September 2, 2009 Category: Allergy & Immunology Source Type: organizations

TMC-MCC (N-trimethyl Chitosan- Mono-N-carboxymethyl Chitosan) Nanocomplexes for Mucosal Delivery of Vaccines.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In this study, for the first time, TMC/MCC complex nanoparticles as a delivery system and as an adjuvant were developed and evaluated to obtain systemic and mucosal immune responses against nasally administered tetanus toxoid (TT). Nanoparticles were developed by complexation between the oppositely charged chitosan derivatives, N-trimethyl chitosan (TMC, polycationic) and mono-N-carboxymethyl chitosan (MCC, polyampholytic) without using any crosslinker for mucosal vaccination. The cellular viability was found to be higher with TMC/MCC complex compared to that of MCC and TMC alone. Size, zeta-potential and morphology of the...
Source: European Journal of Pharmaceutical Sciences - September 2, 2009 Category: Drugs & Pharmacology Authors: Sayın B, Somavarapu S, Li XW, Sesardic D, Senel S, Alpar OH Tags: Eur J Pharm Sci Source Type: journals

No Evidence That Combined DTP-HBV-Hib Vaccine Works BetterEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
07/21/2009, Cochrane Library, There is no evidence that giving infants a combination vaccine for diphtheria (D), tetanus (T), pertussis (P), hepatitis B (HBV), and Haemophilus influenza type B (Hib) protects them as effectively as separate vaccines, according to the results of a new Cochrane review. (Source: Health Behavior News Service)
Source: Health Behavior News Service - August 28, 2009 Category: Consumer Health News Source Type: news

National, state, and local area vaccination coverage among children aged 19-35 months - United States, 2008.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This report describes the 2008 NIS coverage estimates for this series and individual vaccines, 7-valent pneumococcal conjugate vaccine (PCV7), >or=2 doses of hepatitis A vaccine (HepA), and hepatitis B vaccination received in the first 3 days of life (HepB birth dose) among children born during January 2005-June 2007. In 2008, 4:3:1:3:3:1 series coverage was 76.1%, compared with 77.4% in 2007; >or=90% coverage was maintained for all recommended series vaccines, except >or=4 doses of diphtheria, tetanus, and acellular pertussis (DTaP) vaccine. Coverage with >or=3 doses of Haemophilus influenzae type b vaccine (H...
Source: MMWR Morb Mortal Wkl... - August 27, 2009 Category: Epidemiology Tags: MMWR Morb Mortal Wkly Rep Source Type: journals

Medical and Nursing Students with Suboptimal Protective Immunity against Vaccine‐Preventable DiseasesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions. We have determined that there is a certain proportion of healthcare students who are susceptible to certain vaccine‐preventable diseases. The development of an appropriate vaccination strategy is required to decrease the risk of transmission in a hospital setting. (Source: Infect Control Hosp Epidemiol Latest Issue)
Source: Infect Control Hosp Epidemiol Latest Issue - August 26, 2009 Category: Epidemiology Tags: article Original Article Source Type: journals

Combined, Reduced-Antigen Content Tetanus, Diphtheria, and Acellular Pertussis Vaccine (Boostrix): A Review of its Use as a Single-Dose Booster Immunization in Individuals Aged 1064 Years in the USEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: BioDrugs)
Source: BioDrugs - August 26, 2009 Category: Drugs & Pharmacology Authors: Plosker, Greg L. Tags: Adis Drug Evaluation Source Type: journals

Studies of the anti-platelet factor 4/heparin immune response: adapting the enzyme-linked immunosorbent spot assay for detection of memory B cells against complex antigens.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: HIT lacks a strong memory B-cell response, perhaps explaining transience and lack of anamnesis of the anti-PF4/heparin immune response. The technical modifications we describe for the ELISPOT assay, which permit detection of B-cell reactions to complex antigens, could be useful for studying other immunohematologic disorders, for example, drug-dependent thrombocytopenia and acquired hemophilia. PMID: 19709391 [PubMed - as supplied by publisher] (Source: Transfusion)
Source: Transfusion - August 25, 2009 Category: Hematology Authors: Selleng K, Schütt A, Selleng S, Warkentin TE, Greinacher A Tags: Transfusion Source Type: journals