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Total 2036 results found since Jan 2013.

Quiz: Sepsis Science
Bacteria are the most common triggers of sepsis.Credit: Mark Ellisman and Thomas Deerinck, National Center for Microscopy and Imaging Research, University of California San Diego. At least 1.7 million adults in the United States develop a life-threatening condition called sepsis each year. Sepsis is an overwhelming or impaired whole-body immune response that’s most often caused by bacterial infections. However, it can also be caused by viral infections, such as COVID-19 or influenza; fungal infections; or other injuries, including physical trauma.​​ Anyone can get sepsis, but there’s a higher risk ...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - September 13, 2023 Category: Research Authors: Chrissa Chverchko Tags: Being a Scientist Injury and Illness Quiz Research Roundup Sepsis Source Type: blogs

Fight Aging! Newsletter, September 11th 2023
This article reviews the current regulatory role of miR-7 in inflammation and related diseases, including viral infection, autoimmune hepatitis, inflammatory bowel disease, and encephalitis. It expounds on the molecular mechanism by which miR-7 regulates the occurrence of inflammatory diseases. Finally, the existing problems and future development directions of miR-7-based intervention on inflammation and related diseases are discussed to provide new references and help strengthen the understanding of the pathogenesis of inflammation and related diseases, as well as the development of new strategies for clinical interventi...
Source: Fight Aging! - September 10, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Device for Rapid COVID-19 Breath Testing
Researchers at Washington University School of Medicine have developed a COVID-19 breathalyzer test. The technology requires someone to breathe into it just once or twice, and it can then provide an indication if the person is infected with SARS-CoV-...
Source: Medgadget - September 7, 2023 Category: Medical Devices Authors: Conn Hastings Tags: Diagnostics Medicine Public Health wustl WUSTLmed Source Type: blogs

A High Level Popular Science View of the Longevity Industry
The article I'll point out today is an entirely unremarkable, high level tour of the most discussed, most notable portions of the longevity industry and related research efforts. Twenty years ago, we'd all have been delighted to see the media both noticing translational aging research at all, and then actually taking seriously the prospect of treating aging as a medical condition. We've come a long way to now see summary discussions of work on the treatment of aging as business as usual, not really worth mentioning. Still, articles like this miss near all of the really interesting projects, and that is the way of high leve...
Source: Fight Aging! - September 5, 2023 Category: Research Authors: Reason Tags: Healthy Life Extension Community Source Type: blogs

Fight Aging! Newsletter, September 4th 2023
In conclusion, although the contribution of CRF to GrimAgeAccel and FitAgeAccel is relatively low compared to lifestyle-related factors such as smoking, the results suggest that the maintenance of CRF is associated with delayed biological ageing in older men. « Back to Top Release of Acetylcholine is Necessary for the Aging Brain to Compensate for a Lack of Neurogenesis https://www.fightaging.org/archives/2023/09/release-of-acetylcholine-is-necessary-for-the-aging-brain-to-compensate-for-a-lack-of-neurogenesis/ Neurogenesis is the process by which new neurons are created by neural stem ce...
Source: Fight Aging! - September 3, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

More Evidence for Vaccination to Reduce Alzheimer ' s Disease Risk
There is good evidence for the various forms of later life vaccination, such as for herpes zoster or influenza, to reduce the risk of later suffering Alzheimer's disease. One possibility is that people who take the time to obtain a vaccine tend to take better care of their health across the board. Another possibility is that vaccination produces a trained immunity effect that dampens age-related inflammation for a sustained period of time. It may also be the case that suffering from influenza, pneumonia, or similar infectious diseases causes sufficient additional inflammation to move the odds on suffering later neurodegene...
Source: Fight Aging! - August 28, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

A man in his 70s with weakness and syncope
DiscussionBrugada Type 1 ECG changes are associated with sudden cardiac death (SCD) and the occurrence of ventricular dysrhythmias. Patients that develop a Type 1 pattern without any precipitating or provoking factors have a risk of SCD of 0.5-0.8% per year. In patients that only have this pattern induced by a sodium channel blocking agent have a lower rate of SCD (0 - 0.35% per year)[1]. Drugs that have been associated with Brugada ECG patterns include tricyclic antidepressants, anesthetics, cocaine, methadone, antihistamines, electrolyte derangements, and even tramadol. [2]. Our patient had a Brugada Type ...
Source: Dr. Smith's ECG Blog - July 22, 2023 Category: Cardiology Authors: Pendell Source Type: blogs

Pulmonary Arterial Hypertension: Unraveling Its Impact On Heart And Lungs
Conclusion Navigating the complexities of Pulmonary Arterial Hypertension (PAH) might seem daunting. However, with the right knowledge and proactive approach, it’s possible to manage the condition and maintain a good quality of life. PAH, a unique type of high blood pressure affecting the arteries in the lungs, can put extra strain on the heart. Over time, this can lead to heart failure. The condition’s root cause may vary, from genetic factors to other health issues like heart defects, liver disease, or autoimmune diseases. Remember, sometimes the cause remains unknown, resulting in idiopathic pulmonary ...
Source: The EMT Spot - July 19, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: Blood Pressure Source Type: blogs

Fight Aging! Newsletter, July 17th 2023
In conclusion, the longevity-associated genotype of FLT1 may confer increased lifespan by protecting against mortality risk posed by hypertension. We suggest that FLT1 expression in individuals with longevity genotype boosts vascular endothelial resilience mechanisms to counteract hypertension-related stress in vital organs and tissues. Resistance Exercise Slows the Onset of Pathology in a Mouse Model of Alzheimer's Disease https://www.fightaging.org/archives/2023/07/resistance-exercise-slows-the-onset-of-pathology-in-a-mouse-model-of-alzheimers-disease/ With the caveat that mouse models of Alzheimer's...
Source: Fight Aging! - July 16, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

App Converts Smartphone to Clinical Thermometer
Researchers at the University of Washington have developed an app that converts common smartphones into clinical thermometers. Spotting the signs of fever early could make a difference in providing early treatment or beginning a period of isolation t...
Source: Medgadget - July 14, 2023 Category: Medical Devices Authors: Conn Hastings Tags: Diagnostics Emergency Medicine Public Health Telemedicine universityofwashington Source Type: blogs

Senolytic Treatment Fails to Improve Measures of the Immune Response to Influenza in Old Mice
At this point in the development of senolytic therapies to clear harmful, lingering senescent cells from aged tissues, it is more interesting to find an aspect of aging that isn't improved by removal of senescent cells than to continue adding to the long list of age-related conditions and dysfunctions that are meaningfully reversed by senescent cell clearance. Here, researchers show that measures of the immune response to influenza infection in mice are not improved followed treatment with the senolytic combination of dasatinib and quercetin. This is a perhaps surprising result, given the expectation based on evidence to d...
Source: Fight Aging! - July 12, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Bonus Features – July 2, 2023 – Nuance and Epic integrate, 5 in 6 physicians say telemedicine improves continuity of care, news from HFMA, and more
This article will be a weekly roundup of interesting stories, product announcements, new hires, partnerships, research studies, awards, sales, and more. Because there’s so much happening out there in healthcare IT we aren’t able to cover in our full articles, we still want to make sure you’re informed of all the latest news, announcements, and stories happening to help you better do your job. News and Research HHS and the Office of Inspector General released the final rule implementing information blocking penalties, with fines of up to $1 million per violation for vendors and HIE entities. Penalties for providers h...
Source: EMR and HIPAA - July 2, 2023 Category: Information Technology Authors: Brian Eastwood Tags: Health IT Company Healthcare IT Revenue Cycle Management Adam Boehler Asimily Avalon Healthcare Solutions Black Book Cotiviti DAX Express Dennis E. Dahlen DexCare Double Black Imaging Doximity eClinicalWorks eCW Epic Evelyn Source Type: blogs

Can You Follow A Keto Diet With Hypertension?
Conclusion Navigating the maze of diet and health can indeed be a challenge. Especially when it comes to the trendy keto diet and its potential effects on hypertension. So, where do we land on the question, “Can you follow a keto diet with hypertension?” From the studies we’ve reviewed and the real-life experiences we’ve heard, the answer is a cautious yes. It seems a well-managed keto diet could potentially benefit individuals with hypertension, mainly through weight loss, improved metabolic health, and lower blood sugar levels. However, it’s not a one-size-fits-all approach. The key...
Source: The EMT Spot - June 21, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: Blood Pressure Source Type: blogs

Better Health Care Tests, Faster
This article looks at some specific problems and solutions. Speeding up Test Development We’ve seen with COVID-19 how quickly a virus can evolve and how hard it is to design both tests and vaccinations that accommodate different variants. Virax Biolabs uses data from the World Health Organization and others to develop tests quickly. For instance, new viral variants tend to spread in the southern hemisphere before hitting the northern hemisphere in our Winter, so Virax can check existing data to prepare better tests for the North. The company is developing a T-cell diagnostics and profiling platform called Virax Immu...
Source: EMR and HIPAA - June 13, 2023 Category: Information Technology Authors: Andy Oram Tags: Health IT Company Healthcare IT Hospital - Health System Interoperability CLIA COVID-19 Hydreight Immunexpress ixlayer Laboratories Labs Rolland Carlson Sepsis Sepsis Lab Tests Septicyte Shane Madden testing Tomasz George Source Type: blogs

Fight Aging! Newsletter, June 5th 2023
In conclusion, higher BMR might reduce lifespan. The underlying pathways linking to major causes of death and relevant interventions warrant further investigation. Betting Against Progress Turns Out Poorly, But Can Work in the Short Term in a Slow Field https://www.fightaging.org/archives/2023/06/betting-against-progress-turns-out-poorly-but-can-work-in-the-short-term-in-a-slow-field/ Setting oneself up as a spokesperson for "we will not achieve this goal", as the fellow noted here is choosing to do, is a bet against technological progress. A glance at any few decade period in the past two hundred year...
Source: Fight Aging! - June 4, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs