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Developmental Stage Annotation of Drosophila Gene Expression Pattern Images via an Entire Solution Path for LDA.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Gene expression in a developing embryo occurs in particular cells (spatial patterns) in a time-specific manner (temporal patterns), which leads to the differentiation of cell fates. Images of a Drosophila melanogaster embryo at a given developmental stage, showing a particular gene expression pattern revealed by a gene-specific probe, can be compared for spatial overlaps. The comparison is fundamentally important to formulating and testing gene interaction hypotheses. Expression pattern comparison is most biologically meaningful when images from a similar time point (developmental stage) are compared. In this paper, we...
Source: ACM Transactions on Knowledge Discovery from Data - March 1, 2008 Category: Bioinformatics Authors: Ye J, Chen J, Janardan R, Kumar S Tags: ACM Trans Knowl Discov Data Source Type: journals