Efficacy and safety of switching to dolutegravir/lamivudine in virologically suppressed people with HIV-1 aged  ≥ 50 years: week 48 pooled results from the TANGO and SALSA studies
CONCLUSIONS: Among individuals with HIV-1, switching to DTG/3TC maintained high rates of virologic suppression and demonstrated a favorable safety profile, including in those aged ≥ 50 years despite higher prevalence of concomitant medication use and comorbidities.TRIAL REGISTRATION NUMBER: TANGO, NCT03446573 (February 27, 2018); SALSA, NCT04021290 (July 16, 2019).PMID:38515183 | PMC:PMC10958962 | DOI:10.1186/s12981-024-00604-9 (Source: AIDS Research and Therapy)
Source: AIDS Research and Therapy - March 22, 2024 Category: Infectious Diseases Authors: Sharon Walmsley Don E Smith Miguel G órgolas Pedro E Cahn Thomas Lutz Karine Lacombe Princy N Kumar Brian Wynne Richard Grove Gilda Bontempo Riya Moodley Chinyere Okoli Michelle Kisare Bryn Jones Andrew Clark Mounir Ait-Khaled Source Type: research

Efficacy and safety of switching to dolutegravir/lamivudine in virologically suppressed people with HIV-1 aged  ≥ 50 years: week 48 pooled results from the TANGO and SALSA studies
CONCLUSIONS: Among individuals with HIV-1, switching to DTG/3TC maintained high rates of virologic suppression and demonstrated a favorable safety profile, including in those aged ≥ 50 years despite higher prevalence of concomitant medication use and comorbidities.TRIAL REGISTRATION NUMBER: TANGO, NCT03446573 (February 27, 2018); SALSA, NCT04021290 (July 16, 2019).PMID:38515183 | PMC:PMC10958962 | DOI:10.1186/s12981-024-00604-9 (Source: AIDS Research and Therapy)
Source: AIDS Research and Therapy - March 22, 2024 Category: Infectious Diseases Authors: Sharon Walmsley Don E Smith Miguel G órgolas Pedro E Cahn Thomas Lutz Karine Lacombe Princy N Kumar Brian Wynne Richard Grove Gilda Bontempo Riya Moodley Chinyere Okoli Michelle Kisare Bryn Jones Andrew Clark Mounir Ait-Khaled Source Type: research

Efficacy and safety of switching to dolutegravir/lamivudine in virologically suppressed people with HIV-1 aged  ≥ 50 years: week 48 pooled results from the TANGO and SALSA studies
CONCLUSIONS: Among individuals with HIV-1, switching to DTG/3TC maintained high rates of virologic suppression and demonstrated a favorable safety profile, including in those aged ≥ 50 years despite higher prevalence of concomitant medication use and comorbidities.TRIAL REGISTRATION NUMBER: TANGO, NCT03446573 (February 27, 2018); SALSA, NCT04021290 (July 16, 2019).PMID:38515183 | DOI:10.1186/s12981-024-00604-9 (Source: AIDS Research and Therapy)
Source: AIDS Research and Therapy - March 22, 2024 Category: Infectious Diseases Authors: Sharon Walmsley Don E Smith Miguel G órgolas Pedro E Cahn Thomas Lutz Karine Lacombe Princy N Kumar Brian Wynne Richard Grove Gilda Bontempo Riya Moodley Chinyere Okoli Michelle Kisare Bryn Jones Andrew Clark Mounir Ait-Khaled Source Type: research

Efficacy and safety of switching to dolutegravir/lamivudine in virologically suppressed people with HIV-1 aged  ≥ 50 years: week 48 pooled results from the TANGO and SALSA studies
As the population of people with HIV ages, concerns over managing age-related comorbidities, polypharmacy, immune recovery, and drug-drug interactions while maintaining viral suppression have arisen. We presen... (Source: AIDS Research and Therapy)
Source: AIDS Research and Therapy - March 21, 2024 Category: Infectious Diseases Authors: Sharon Walmsley, Don E. Smith, Miguel G órgolas, Pedro E. Cahn, Thomas Lutz, Karine Lacombe, Princy N. Kumar, Brian Wynne, Richard Grove, Gilda Bontempo, Riya Moodley, Chinyere Okoli, Michelle Kisare, Bryn Jones, Andrew Clark and Mounir Ait-Khaled Tags: Research Source Type: research

Assessing high-risk sexual practices associated with human immunodeficiency virus infection among young female sex workers in Lubumbashi, Democratic Republic of the Congo: a cross-sectional study
CONCLUSION: The study reveals a concerning trend of higher hospital HIV prevalence among YFSWs compared to the general Congolese population. It also highlights a significant link between high-risk sexual practices and HIV infection, highlighting the need for urgent interventions.PMID:38504236 | PMC:PMC10949734 | DOI:10.1186/s12981-024-00602-x (Source: AIDS Research and Therapy)
Source: AIDS Research and Therapy - March 20, 2024 Category: Infectious Diseases Authors: Olivier Mukuku Yannick Nkiambi Kiakuvue Georges Yumba Numbi Bienvenu Mukuku Ruhindiza Christian Kakisingi Claude Mulumba Mwamba Joe Kabongo Katabwa Source Type: research

Assessing high-risk sexual practices associated with human immunodeficiency virus infection among young female sex workers in Lubumbashi, Democratic Republic of the Congo: a cross-sectional study
CONCLUSION: The study reveals a concerning trend of higher hospital HIV prevalence among YFSWs compared to the general Congolese population. It also highlights a significant link between high-risk sexual practices and HIV infection, highlighting the need for urgent interventions.PMID:38504236 | DOI:10.1186/s12981-024-00602-x (Source: AIDS Research and Therapy)
Source: AIDS Research and Therapy - March 20, 2024 Category: Infectious Diseases Authors: Olivier Mukuku Yannick Nkiambi Kiakuvue Georges Yumba Numbi Bienvenu Mukuku Ruhindiza Christian Kakisingi Claude Mulumba Mwamba Joe Kabongo Katabwa Source Type: research

Assessing high-risk sexual practices associated with human immunodeficiency virus infection among young female sex workers in Lubumbashi, Democratic Republic of the Congo: a cross-sectional study
CONCLUSION: The study reveals a concerning trend of higher hospital HIV prevalence among YFSWs compared to the general Congolese population. It also highlights a significant link between high-risk sexual practices and HIV infection, highlighting the need for urgent interventions.PMID:38504236 | DOI:10.1186/s12981-024-00602-x (Source: AIDS Research and Therapy)
Source: AIDS Research and Therapy - March 20, 2024 Category: Infectious Diseases Authors: Olivier Mukuku Yannick Nkiambi Kiakuvue Georges Yumba Numbi Bienvenu Mukuku Ruhindiza Christian Kakisingi Claude Mulumba Mwamba Joe Kabongo Katabwa Source Type: research

Assessing high-risk sexual practices associated with human immunodeficiency virus infection among young female sex workers in Lubumbashi, Democratic Republic of the Congo: a cross-sectional study
Young female sex workers (YFSWs) face a higher risk of HIV infection compared to older workers, but there is a lack of comprehensive data on their sexual practices and HIV infection risks, which may present un... (Source: AIDS Research and Therapy)
Source: AIDS Research and Therapy - March 19, 2024 Category: Infectious Diseases Authors: Olivier Mukuku, Yannick Nkiambi Kiakuvue, Georges Yumba Numbi, Bienvenu Mukuku Ruhindiza, Christian Kakisingi, Claude Mulumba Mwamba and Joe Kabongo Katabwa Tags: Research Source Type: research

Factors influencing rapid antiretroviral therapy initiation in Jiulongpo, Chongqing, China: a retrospective cohort from 2018 to 2022
CONCLUSIONS: A higher CD4 cell counts and receiving care in local public hospitals may deter rapid ART initiation. Providing CD4 counts results at diagnosis and offering testing and treatment in the same facility could enhance the rate of rapid ART initiation.PMID:38494484 | PMC:PMC10944594 | DOI:10.1186/s12981-024-00601-y (Source: AIDS Research and Therapy)
Source: AIDS Research and Therapy - March 18, 2024 Category: Infectious Diseases Authors: Cheng Chen Hao Chen Lingli Wu Qin Gong Jingchun He Source Type: research

Factors influencing rapid antiretroviral therapy initiation in Jiulongpo, Chongqing, China: a retrospective cohort from 2018 to 2022
CONCLUSIONS: A higher CD4 cell counts and receiving care in local public hospitals may deter rapid ART initiation. Providing CD4 counts results at diagnosis and offering testing and treatment in the same facility could enhance the rate of rapid ART initiation.PMID:38494484 | DOI:10.1186/s12981-024-00601-y (Source: AIDS Research and Therapy)
Source: AIDS Research and Therapy - March 18, 2024 Category: Infectious Diseases Authors: Cheng Chen Hao Chen Lingli Wu Qin Gong Jingchun He Source Type: research

Factors influencing rapid antiretroviral therapy initiation in Jiulongpo, Chongqing, China: a retrospective cohort from 2018 to 2022
Antiretroviral Therapy (ART) is pivotal in extending the lives of people living with HIV (PLWH) and minimizing transmission. Rapid ART initiation, defined as commencing ART within seven days of HIV diagnosis, ... (Source: AIDS Research and Therapy)
Source: AIDS Research and Therapy - March 17, 2024 Category: Infectious Diseases Authors: Cheng Chen, Hao Chen, Lingli Wu, Qin Gong and Jingchun He Tags: Research Source Type: research

Support, not blame: safe partner disclosure among women diagnosed with HIV late in pregnancy in South Africa and Uganda
CONCLUSION: HIV diagnosis late in pregnancy amplifies existing difficulties among pregnant women. Late ANC initiation is an indicator for the likelihood that a pregnant woman is highly vulnerable and needs safeguarding. Respective health programmes should be prepared to offer women initiating ANC late in pregnancy additional support and referral to complementary programmes to achieve safe partner disclosure and good health.PMID:38481233 | PMC:PMC10938717 | DOI:10.1186/s12981-024-00600-z (Source: AIDS Research and Therapy)
Source: AIDS Research and Therapy - March 14, 2024 Category: Infectious Diseases Authors: Adelline Twimukye Yussif Alhassan Beate Ringwald Thokozile Malaba Landon Myer Catriona Waitt Mohammed Lamorde Helen Reynolds Saye Khoo Miriam Taegtmeyer Source Type: research

Support, not blame: safe partner disclosure among women diagnosed with HIV late in pregnancy in South Africa and Uganda
CONCLUSION: HIV diagnosis late in pregnancy amplifies existing difficulties among pregnant women. Late ANC initiation is an indicator for the likelihood that a pregnant woman is highly vulnerable and needs safeguarding. Respective health programmes should be prepared to offer women initiating ANC late in pregnancy additional support and referral to complementary programmes to achieve safe partner disclosure and good health.PMID:38481233 | PMC:PMC10938717 | DOI:10.1186/s12981-024-00600-z (Source: AIDS Research and Therapy)
Source: AIDS Research and Therapy - March 14, 2024 Category: Infectious Diseases Authors: Adelline Twimukye Yussif Alhassan Beate Ringwald Thokozile Malaba Landon Myer Catriona Waitt Mohammed Lamorde Helen Reynolds Saye Khoo Miriam Taegtmeyer Source Type: research

Support, not blame: safe partner disclosure among women diagnosed with HIV late in pregnancy in South Africa and Uganda
CONCLUSION: HIV diagnosis late in pregnancy amplifies existing difficulties among pregnant women. Late ANC initiation is an indicator for the likelihood that a pregnant woman is highly vulnerable and needs safeguarding. Respective health programmes should be prepared to offer women initiating ANC late in pregnancy additional support and referral to complementary programmes to achieve safe partner disclosure and good health.PMID:38481233 | PMC:PMC10938717 | DOI:10.1186/s12981-024-00600-z (Source: AIDS Research and Therapy)
Source: AIDS Research and Therapy - March 14, 2024 Category: Infectious Diseases Authors: Adelline Twimukye Yussif Alhassan Beate Ringwald Thokozile Malaba Landon Myer Catriona Waitt Mohammed Lamorde Helen Reynolds Saye Khoo Miriam Taegtmeyer Source Type: research

Support, not blame: safe partner disclosure among women diagnosed with HIV late in pregnancy in South Africa and Uganda
CONCLUSION: HIV diagnosis late in pregnancy amplifies existing difficulties among pregnant women. Late ANC initiation is an indicator for the likelihood that a pregnant woman is highly vulnerable and needs safeguarding. Respective health programmes should be prepared to offer women initiating ANC late in pregnancy additional support and referral to complementary programmes to achieve safe partner disclosure and good health.PMID:38481233 | DOI:10.1186/s12981-024-00600-z (Source: AIDS Research and Therapy)
Source: AIDS Research and Therapy - March 14, 2024 Category: Infectious Diseases Authors: Adelline Twimukye Yussif Alhassan Beate Ringwald Thokozile Malaba Landon Myer Catriona Waitt Mohammed Lamorde Helen Reynolds Saye Khoo Miriam Taegtmeyer Source Type: research