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1299 records returned

HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Hydrocodone Bitartrate And Acetaminophen) [Qualitest Pharmaceuticals]email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Updated Date: Nov 19, 2009 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))
Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) - November 19, 2009 Category: Drugs & Pharmacology Source Type: organizations

Common herbal medicine may prevent acetaminophen-related liver damage, says researcheremail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
A well-known Eastern medicine supplement may help avoid the most common cause of liver transplantation, according to a new study. The finding came as a surprise to the scientists, who used a number of advanced genetic and genomic techniques in mice to identify a molecular pathway that counters acetaminophen toxicity, which leads to liver failure. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - November 19, 2009 Category: Science Source Type: news

An integrative genomic analysis identifies Bhmt2 as a diet-dependent genetic factor protecting against acetaminophen-induced liver toxicity [LETTERS]email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Acetaminophen-induced liver toxicity is the most frequent precipitating cause of acute liver failure and liver transplant, but contemporary medical practice has mainly focused on patient management after a liver injury has been induced. An integrative genetic, transcriptional, and two-dimensional NMR-based metabolomic analysis performed using multiple inbred mouse strains, along with knowledge-based filtering of these data, identified betaine-homocysteine methyltransferase 2 (Bhmt2) as a diet-dependent genetic factor that affected susceptibility to acetaminophen-induced liver toxicity in mice. Through an effect on methioni...
Source: Genome Research - November 19, 2009 Category: Genetics & Stem Cells Authors: Liu, H.-H., Lu, P., Guo, Y., Farrell, E., Zhang, X., Zheng, M., Bosano, B., Zhang, Z., Allard, J., Liao, G., Fu, S., Chen, J., Dolim, K., Kuroda, A., Usuka, J., Cheng, J., Tao, W., Welch, K., Liu, Y., Pease, J., de Keczer, S. A., Masjedizadeh, M., Hu, J.- Tags: LETTERS Source Type: journals

Acetaminophen-Related Liver Damage May Be Prevented By Common Herbal Medicineemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
A well-known Eastern medicine supplement may help avoid the most common cause of liver transplantation, according to a study by researchers at the Stanford University School of Medicine. The finding came as a surprise to the scientists, who used a number of advanced genetic and genomic techniques in mice to identify a molecular pathway that counters acetaminophen toxicity, which leads to liver failure. (Source: Genetics News From Medical News Today)
Source: Genetics News From Medical News Today - November 18, 2009 Category: Genetics & Stem Cells Tags: Liver Disease / Hepatitis Source Type: news

Acetaminophen-Related Liver Damage May Be Prevented By Common Herbal Medicineemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
A well-known Eastern medicine supplement may help avoid the most common cause of liver transplantation, according to a study by researchers at the Stanford University School of Medicine. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 18, 2009 Category: Consumer Health News Tags: Liver Disease / Hepatitis Source Type: news

BioElectronics Technology More Effective Than Extra Strength Tylenol(R) In Reducing Muscle Soreness In Clinical Studyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
BioElectronics Corp. (PINKSHEETS: BIEL) announced that its disposable drug-free anti-inflammatory devices proved to be significantly more effective than acetaminophen in a clinical study of Delayed Onset Muscle Soreness (DOMS). (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 17, 2009 Category: Consumer Health News Tags: Pain / Anesthetics Source Type: news

BioElectronics Technology More Effective Than Extra Strength Tylenol(R) In Reducing Muscle Soreness In Clinical Studyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
BioElectronics Corp. (PINKSHEETS: BIEL) announced that its disposable drug-free anti-inflammatory devices proved to be significantly more effective than acetaminophen in a clinical study of Delayed Onset Muscle Soreness (DOMS). The study tested the effectiveness of ActiPatch® Therapy versus acetaminophen in reducing the pain of Delayed Onset Muscle Soreness, a condition associated with increased physical exertion. (Source: Pain / Anesthetics News From Medical News Today)
Source: Pain / Anesthetics News From Medical News Today - November 17, 2009 Category: Anesthesiology Tags: Pain / Anesthetics Source Type: news

Acetaminophen: Good painkiller can be deadly if overusedemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
You may believe acetaminophen, the aspirin-free pain reliever found in Tylenol, is one of the safest painkillers on the market. And used properly, it is. But acetaminophen is also the leading cause of acute liver failure in the United States because taking just slightly more than the maximum reco... (Source: Wash Post Health)
Source: Wash Post Health - November 17, 2009 Category: Consumer Health News Authors: Post Tags: Acetaminophen: Good painkiller can be deadly if overused Source Type: news

Therapeutic dose of acetaminophen may induce fulminant hepatitis in the presence of risk factors: a report of two casesemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
(Source: British Journal of Anaesthesia)
Source: British Journal of Anaesthesia - November 16, 2009 Category: Anesthesiology Authors: Forget, P., Wittebole, X., Laterre, P.-F. Tags: Correspondence Source Type: journals

Certain lots of Tylenol [paracetamol, acetaminophen] Arthritis Pain Caplets are being voluntarily recalled in the US.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
(Source: Reactions)
Source: Reactions - November 16, 2009 Category: Drugs & Pharmacology Tags: Short communication Source Type: journals

Paracetamol (Acetaminophen) is Safe and Effective for Treatment of Postoperative Third Molar Extraction Painemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
This study's aim was to assess the benefits and harmful effects of Paracetamol (acetaminophen) for treatment of post-operative pain associated with extraction of lower third molars when compared to placebo.Source of Funding: Internal funding from the University of Manchester (UK) and the University of Amsterdam (Netherlands). No external sources of funding supplied.Type of Study/Design: Systematic review with meta-analysis.Level of Evidence: Level 1: Good-quality, patient-oriented evidence.Strength of Recommendation Grade: Grade B: Inconsistent or limited-quality patient-oriented evidence. (Source: The Journal of Evidence-...
Source: The Journal of Evidence-Based Dental Practice - November 14, 2009 Category: Dentistry Authors: Robert Weyant Tags: Reviews of Systematic Reviews Source Type: journals

Cadence Pharmaceuticals Announces FDA Extends New Drug Application Review For Intravenous Acetaminophen By Three Monthsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Cadence Pharmaceuticals, Inc. (Nasdaq: CADX) announced that the U.S. Food and Drug Administration (FDA) has extended the Prescription Drug User Fee Act (PDUFA) goal date for its Priority Review of the New Drug Application (NDA) for intravenous (IV) acetaminophen by three months. The extended PDUFA goal date is February 12, 2010. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 14, 2009 Category: Consumer Health News Tags: Pain / Anesthetics Source Type: news

Cadence Pharmaceuticals Announces FDA Extends New Drug Application Review For Intravenous Acetaminophen By Three Monthsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Cadence Pharmaceuticals, Inc. (Nasdaq: CADX) announced that the U.S. Food and Drug Administration (FDA) has extended the Prescription Drug User Fee Act (PDUFA) goal date for its Priority Review of the New Drug Application (NDA) for intravenous (IV) acetaminophen by three months. The extended PDUFA goal date is February 12, 2010. (Source: Pain / Anesthetics News From Medical News Today)
Source: Pain / Anesthetics News From Medical News Today - November 14, 2009 Category: Anesthesiology Tags: Pain / Anesthetics Source Type: news

High-Mobility Group Box-1 Protein and Keratin-18, Circulating Serum Proteins Informative of Acetaminophen-Induced Necrosis and Apoptosis In Vivoemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Drug-induced hepatotoxicity represents a major clinical problem and an impediment to new medicine development. Serum biomarkers hold the potential to provide information about pathways leading to cellular responses within inaccessible tissues, which can inform the medicinal chemist and the clinician with respect to safe drug design and use. Hepatocyte apoptosis, necrosis, and innate immune activation have been defined as features of the toxicological response associated with the hepatotoxin acetaminophen (APAP). Within this investigation, we have unambiguously identified and characterized by liquid chromatography-tandem ma...
Source: Toxicological Sciences - November 13, 2009 Category: Toxicology Authors: Antoine, D. J., Williams, D. P., Kipar, A., Jenkins, R. E., Regan, S. L., Sathish, J. G., Kitteringham, N. R., Park, B. K. Tags: SAFETY EVALUATION Source Type: journals

Cadence Pharmaceuticals Announces FDA Extends New Drug Application Review for Intravenous Acetaminophen by Three Monthsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
SAN DIEGO, Calif., Nov. 13 /PRNewswire-FirstCall/ -- Cadence Pharmaceuticals, Inc. announced today that the U.S. Food and Drug Administration (FDA) has extended the Prescription Drug User Fee Act (PDUFA) goal date for its Priority Review of the... (Source: Drugs.com - New Drug Applications)
Source: Drugs.com - New Drug Applications - November 13, 2009 Category: Drugs & Pharmacology Source Type: news

BUTALBITAL, ACETAMINOPHEN, CAFFEINE, AND CODEINE PHOSPHATE (Codeine Phosphate, Butalbital, Caffeine, And Acetaminophen Capsule) Capsule [Physicians Total Care, Inc.]email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Updated Date: Nov 13, 2009 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))
Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) - November 13, 2009 Category: Drugs & Pharmacology Source Type: organizations

Acetaminophen Use Linked to Asthma and Wheezingemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
In children and adults, acetaminophen use may be associated with an increased risk of asthma and wheezing, according to a study published in the November issue of Chest. (Source: Modern Medicine)
Source: Modern Medicine - November 13, 2009 Category: Journals (General) Source Type: info

Acetaminophen could up asthma, wheezing riskemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
NEW YORK (Reuters Health) - An analysis of 19 studies provides additional evidence of increased asthma risk in children and adults given acetaminophen. (Source: Reuters: Health)
Source: Reuters: Health - November 12, 2009 Category: Consumer Health News Tags: healthNews Source Type: news

Acetaminophen Could Up Asthma, Wheezing Riskemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
An analysis of 19 studies provides additional evidence of increased asthma risk in children and adults given acetaminophen. Source: Reuters Health Related MedlinePlus Topics: Asthma, Drug Safety, Pain Relievers (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - November 12, 2009 Category: Consumer Health News Source Type: consumer

The therapeutic effect of bone marrow-derived liver cells in the phenotypic correction of murine hemophilia Aemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
The transdifferentiation of bone marrow cells (BMCs) into hepatocytes has created enormous interest in applying this process to the development of cellular medicine for degenerative and genetic diseases. Because the liver is the primary site of factor VIII (FVIII) synthesis, we hypothesized that the partial replacement of mutated liver cells by healthy cells in hemophilia A mice could manage the severity of the bleeding disorder. We perturbed the host liver with acetaminophen to facilitate the engraftment and hepatic differentiation of lineage-depleted enhanced green fluorescent protein-expressing BMCs. Immunohistochemistr...
Source: Blood - November 12, 2009 Category: Hematology Authors: Yadav, N., Kanjirakkuzhiyil, S., Kumar, S., Jain, M., Halder, A., Saxena, R., Mukhopadhyay, A. Tags: Thrombosis and Hemostasis Source Type: journals

BioElectronics To Announce Results Of Acetaminophen Comparison Studyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
BioElectronics Corp. (PINKSHEETS: BIEL), the maker of inexpensive, disposable drug-free anti-inflammatory devices, announced that results from the recently completed acetaminophen comparison study will be released on Monday, November 16th after the close of the market. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 12, 2009 Category: Consumer Health News Tags: Pain / Anesthetics Source Type: news

BioElectronics To Announce Results Of Acetaminophen Comparison Studyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
BioElectronics Corp. (PINKSHEETS: BIEL), the maker of inexpensive, disposable drug-free anti-inflammatory devices, announced that results from the recently completed acetaminophen comparison study will be released on Monday, November 16th after the close of the market. The study compares the effects of ActiPatch® Therapy to acetaminophen in the form of Extra Strength Tylenol® for the treatment of Delayed Onset Muscle Soreness (DOMS). (Source: Pain / Anesthetics News From Medical News Today)
Source: Pain / Anesthetics News From Medical News Today - November 12, 2009 Category: Anesthesiology Tags: Pain / Anesthetics Source Type: news

ACETAMINOPHEN AND CODEINE PHOSPHATEtablet [Physicians Total Care, Inc.]email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Updated Date: Nov 12, 2009 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))
Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) - November 12, 2009 Category: Drugs & Pharmacology Source Type: organizations

Preoperative opioid consumption increases morphine requirement after leg amputation.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
CONCLUSION: Despite the use of regional anesthesia, chronic opioid consumption before leg amputation is associated with increased postoperative morphine consumption and phantom limb pain. PMID: 19908106 [PubMed - as supplied by publisher] (Source: Canadian Journal of Anaesthesia)
Source: Canadian Journal of Anaesthesia - November 12, 2009 Category: Anesthesiology Authors: Roullet S, Nouette-Gaulain K, Biais M, Bernard N, Bénard A, Revel P, Capdevila X, Sztark F Tags: Can J Anaesth Source Type: journals

Occurrence and fate of pharmaceuticals in wastewater treatment plants and rivers in Korea.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
We measured 25 pharmaceuticals in ten municipal wastewater treatment plants (WWTPs), one hospital WWTP and five rivers in Korea. In the municipal WWTP influents, acetaminophen, acetylsalicylic acid and caffeine showed relatively high concentrations. The occurrence of pharmaceuticals in the wastewater seems to be influenced by production and consumption of pharmaceuticals. The hospital WWTP influent showed higher total concentrations of pharmaceuticals than the municipal WWTPs, and caffeine, ciprofloxacin and acetaminophen were dominant. In the rivers, caffeine was dominant, and the distribution of pharmaceuticals was r...
Source: Environmental Pollution - November 12, 2009 Category: Environmental Health Authors: Sim WJ, Lee JW, Oh JE Tags: Environ Pollut Source Type: journals

BioElectronics Corporation: BioElectronics to Announce Results of Acetaminophen Comparison Studyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
FREDERICK, MD (MARKET WIRE) BioElectronics Corp. (PINKSHEETS: BIEL), the maker of inexpensive, disposable drug-free anti-inflammatory devices, today announced that results from the recently completed acetaminophen comparison study will be released on Monday, November 16th after the close of the market. The study compares the effects of ActiPatch(R) Therapy to acetaminophen in the form of Extra Strength Tylenol(R) for the treatment of Delayed Onset Muscle Soreness (DOMS). (Source: Market Wire - Pharmaceuticals and Biotech)
Source: Market Wire - Pharmaceuticals and Biotech - November 11, 2009 Category: Pharmaceuticals Tags: Pharmaceuticals and Biotech BIEL Source Type: news

Synthesis of Cholesterol-Conjugated Magnetic Nanoparticles for Purification of Human Paraoxonase 1.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
In this study, a novel purification strategy was employed to purify the PON1 by using cholesterol-conjugated magnetic nanoparticles. Magnetic nanoparticles were synthesized and conjugated with cholesterol through diazotized p-aminohippuric acid. In Fourier transform infrared spectrum of cholesterol-p-aminohippuric acid-Fe(3)O(4) nanoparticles, the appearance of peaks at 3,358.3, 1,645 cm(-1), and at 2,334.9 cm(-1) confirmed the conjugation. The molecular weight of purified PON1 was nearly 45 kDa on sodium dodecyl sulfate (SDS)-polyacrylamide gel electrophoresis (PAGE), and isoelectric point was 5.3. The specific activity w...
Source: Applied Biochemistry and Biotechnology - November 10, 2009 Category: Biochemistry Authors: Samra ZQ, Shabir S, Rehmat Z, Zaman M, Nazir A, Dar N, Athar MA Tags: Appl Biochem Biotechnol Source Type: journals

Acetaminophen link to asthma risk supportedemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Results from a systematic review and meta-analysis support an association between use of the analgesic acetaminophen and an increased risk for asthma in both children and adults. (Source: MedWire News - Respiratory)
Source: MedWire News - Respiratory - November 9, 2009 Category: Respiratory Medicine Source Type: news

Acetaminophen link to asthma risk supportedemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Results from a systematic review and meta-analysis support an association between use of the analgesic acetaminophen and an increased risk for asthma in both children and adults. (Source: MedWire News - Pediatrics)
Source: MedWire News - Pediatrics - November 9, 2009 Category: Pediatrics Source Type: news

Effect of a weight-based prescribing method within an electronic health record on prescribing errors.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
CONCLUSION: An automated weight-based dosing calculator integrated into an EHR system in the outpatient setting significantly reduced medication prescribing errors for antipyretics prescribed to pediatric patients. This effect appeared to be strongest for reducing overdose errors. PMID: 19890088 [PubMed - in process] (Source: American Journal of Health-System Pharmacy : AJHP)
Source: American Journal of Health-System Pharmacy : AJHP - November 7, 2009 Category: Drugs & Pharmacology Authors: Ginzburg R, Barr WB, Harris M, Munshi S Tags: Am J Health Syst Pharm Source Type: journals

Acetaminophen May Be Linked To Asthma In Children And Adultsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
New research shows that the widely used pain reliever acetaminophen may be associated with an increased risk of asthma and wheezing in both children and adults exposed to the drug. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 6, 2009 Category: Consumer Health News Tags: Pain / Anesthetics Source Type: news

Acetaminophen May Be Linked To Asthma In Children And Adultsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
New research shows that the widely used pain reliever acetaminophen may be associated with an increased risk of asthma and wheezing in both children and adults exposed to the drug. Researchers from the University of British Columbia, Vancouver, BC, Canada, conducted a systematic review and metaanalysis of 19 clinical studies (total subjects=425,140) that compared the risk of asthma or wheezing with acetaminophen exposure. (Source: Pain / Anesthetics News From Medical News Today)
Source: Pain / Anesthetics News From Medical News Today - November 6, 2009 Category: Anesthesiology Tags: Pain / Anesthetics Source Type: news

Acetaminophen May Be Linked to Asthma Riskemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
(Source: eMedicineHealth.com)
Source: eMedicineHealth.com - November 6, 2009 Category: Journals (General) Source Type: info

Acetaminophen May Be Linked to Asthma Riskemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Title: Acetaminophen May Be Linked to Asthma RiskCategory: Health NewsCreated: 11/6/2009 10:50:00 AMLast Editorial Review: 11/6/2009 10:50:12 AM (Source: MedicineNet Asthma General)
Source: MedicineNet Asthma General - November 6, 2009 Category: Respiratory Medicine Source Type: consumer

Acetaminophen may cause asthmaemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
New research shows that the widely used pain reliever acetaminophen appears to be linked to an increased risk of asthma and wheezing in both children and adults exposed to the drug. Scientists from the University of British Columbia, Vancouver, BC, Canada, conducted a systematic review and metaanalysis of 19 clinical studies (total subjects=425,140) that compared the risk of asthma or wheezing with acetaminophen exposure........ (Source: Medicineworld.org: New Article Alert)
Source: Medicineworld.org: New Article Alert - November 5, 2009 Category: Consumer Health News Source Type: info

Acetaminophen may be linked to asthma in children and adultsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
(American College of Chest Physicians) New research shows that the popular pain reliever, acetaminophen, may be tied to asthma in both children and adults. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 5, 2009 Category: Global & Universal Source Type: news

Acetaminophen May Be Linked To Asthma In Children And Adultsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
New research shows that the popular pain reliever, acetaminophen, may be tied to asthma in both children and adults. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - November 5, 2009 Category: Science Source Type: news

Acetaminophen May Be Linked to Asthma Riskemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
The popular pain and fever reliever acetaminophen may be linked with an increased risk of asthma in children and adults, according to a new research review of previously published studies. (Source: WebMD Health)
Source: WebMD Health - November 5, 2009 Category: Consumer Health News Source Type: news

VICODIN (Hydrocodone Bitartrate And Acetaminophen) Tablet [Abbott Laboratories]email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Updated Date: Nov 4, 2009 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))
Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) - November 4, 2009 Category: Drugs & Pharmacology Source Type: organizations

Acetaminophen combinations protect against iron-induced cardiac damage in gerbils.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
This study tested if acetaminophen, N-methyl-D-glucamine dithiocarbamate (NMGDTC), deferoxamine, and combinations of these agents reduce excess iron content, prevent iron-induced pathology, reduce cardiac arrhythmias, and reduce mortality in iron-overloaded gerbils. Eight groups of 16 gerbils received iron dextran injections (ferric hydroxide dextran complex, 120 mg/kg, ip) or saline solution (controls) twice/wk for 8 wk. The 8 groups were treated every Monday, Wednesday, and Friday with one of the following: saline control, acetaminophen, 150 mg/kg, ip), acetaminophen (150 mg/kg, po), deferoxamine, 83 mg/kg, ip), NMGDTC (...
Source: Annals of Clinical and Laboratory Science - November 3, 2009 Category: Laboratory Medicine Authors: Walker EM, Morrison RG, Dornon L, Laurino JP, Walker SM, Studeny M, Wehner PS, Rice KM, Wu M, Blough ER Tags: Ann Clin Lab Sci Source Type: journals

BUTALBITAL, ACETAMINOPHEN, CAFFEINE AND CODEINE PHOSPHATEcapsule [Breckenridge Pharmaceutical, Inc.]email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Updated Date: Nov 3, 2009 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))
Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) - November 3, 2009 Category: Drugs & Pharmacology Source Type: organizations

A retrospective evaluation of shortened-duration oral N-acetylcysteine for the treatment of acetaminophen poisoning.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion: Treatment with shortened-course oral NAC in patients meeting criteria for early discontinuation may be an effective treatment option in a sizeable proportion of individuals with potentially toxic acetaminophen ingestions. PMID: 19876849 [PubMed - in process] (Source: Journal of Medical Toxicology)
Source: Journal of Medical Toxicology - November 1, 2009 Category: Toxicology Authors: Betten D, Burner EE, Thomas SC, Tomaszewski C, Clark RF Tags: J Med Toxicol Source Type: journals

Dosing time based on molecular mechanism of biological clock of hepatic drug metabolic enzyme.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
The mammalian circadian pacemaker stays in the paired suprachiasmatic nuclei (SCN). Recent several studies reveal that the circadian rhythms of physiology and behavior are controlled by clock genes. In addition, the effectiveness and toxicity of many drugs vary depending on dosing time associated with 24-h rhythms of biochemical, physiological, and behavioral processes under the control of the circadian clock. Acetaminophen (APAP) is a widely used analgesic drug, and is mainly biotransformed and eliminated as nontoxic conjugates with glucuronic acid and sulfuric acid. Only a small portion of the dose is mainly bioactiv...
Source: Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan - November 1, 2009 Category: Drugs & Pharmacology Authors: Matsunaga N Tags: Yakugaku Zasshi Source Type: journals

Prenatal acetaminophen exposure linked to risk for wheeze in childrenemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Prenatal exposure to the analgesic acetaminophen is associated with an increased risk for wheeze among inner-city minority children, and this risk is influenced by a common functional polymorphism, results of a US study suggest. (Source: MedWire News - Respiratory)
Source: MedWire News - Respiratory - October 29, 2009 Category: Respiratory Medicine Source Type: news

Prenatal acetaminophen exposure linked to risk for wheeze in childrenemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Prenatal exposure to the analgesic acetaminophen is associated with an increased risk for wheeze among inner-city minority children, and this risk is influenced by a common functional polymorphism, results of a US study suggest. (Source: MedWire News - Pediatrics)
Source: MedWire News - Pediatrics - October 29, 2009 Category: Pediatrics Source Type: news

FDA Safety Changes: Ultram, Ultracet, Sustiva, Kayexalateemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
The FDA has approved safety labeling revisions for tramadol HCl tablets, tramadol plus acetaminophen tablets, efavirenz capsules and tablets, and sodium polystyrene sulfonate powder. Medscape Medical News (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - October 28, 2009 Category: Consumer Health News Tags: Pharmacist Source Type: news

Development of Hepatic Failure Despite Use of Intravenous Acetylcysteine After a Massive Ingestion of Acetaminophen and Diphenhydramineemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
3 out of 5 stars DEVELOPMENT OF HEPATIC FAILURE DESPITE USE OF INTRAVENOUS ACETYLCYSTEINE AFTER A MASSIVE INGESTION OF ACETAMINOPHEN AND DIPHENHYDRAMINE. Schwartz EA et al. Ann Emerg Med Sept. 2009;54:421-423. Abstract This uncommonly interesting case report describes a 48-year-old woman who ingested 150 tablets of Tylenol PM, each containing 500 mg acetaminophen and 25 mg diphenhydramine.  On arrival at hospital, she had clear signs of anticholinergic overdose (tachycardia, dry skin, encephalopathy) but normal liver enzymes and INR.  The initial 4 hour acetaminophen (APAP) level — 104 mcg/ml — was below the ...
Source: The Poison Review - October 28, 2009 Category: Toxicology Authors: Leon Tags: Medical Acetaminophen anticholinergic antidote diphenhydramine massive ingestion NAC Source Type: info

Outcome of acute liver failure in the elderlyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
In conclusion, in contrast to previous studies, we have demonstrated a relatively good spontaneous survival rate for older patients with ALF when it is corrected for etiology. However, overall survival was better for younger non-acetaminophen patients. Fewer older patients were listed for transplantation. Liver Transpl 15:1481-1487, 2009. © 2009 AASLD. (Source: Liver Transplantation)
Source: Liver Transplantation - October 28, 2009 Category: Transplant Surgery Authors: Frank V. Schiødt, Raymond T. Chung, Michael L. Schilsky, J. Eileen Hay, Erik Christensen, William M. Lee, Acute Liver Failure Study Group Tags: Original Articles Source Type: journals

ACETAMINOPHEN AND CODEINE PHOSPHATEsolution [Hi-Tech Pharmacal Co., Inc.]email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Updated Date: Oct 27, 2009 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))
Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) - October 27, 2009 Category: Drugs & Pharmacology Source Type: organizations

BUTALBITAL, ACETAMINOPHEN, CAFFEINE AND CODEINE PHOSPHATEcapsule [Breckenridge Pharmaceutical, Inc.]email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Updated Date: Oct 27, 2009 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))
Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) - October 27, 2009 Category: Drugs & Pharmacology Source Type: organizations