Filaggrin Mutation Status and Prevention of Atopic Dermatitis with Maternal Probiotic Supplementation
Acta Derm Venereol. 2024 Apr 24;104:adv24360. doi: 10.2340/actadv.v104.24360.ABSTRACTThe World Allergy Organization recommends probiotics in the prevention of atopic dermatitis in high-risk populations. Mutations in the filaggrin gene (FLG) result in an increased risk of atopic dermatitis through disruption of the skin keratin layer. This exploratory study investigated whether the preventive effect of maternal probiotics was evident in children with and without FLG mutations. DNA was collected from children (n = 228) from the Probiotic in the Prevention of Allergy among Children in Trondheim (ProPACT) study. Samples were a...
Source: Acta Dermato-Venereologica - April 24, 2024 Category: Dermatology Authors: Dinastry Pramadita Zakiudin Jacob P Thyssen Claus Zachariae Vibeke Videm Torbj ørn Øien Melanie Rae Simpson Source Type: research

Prognostic Value of the Neutrophil-to-lymphocyte Ratio, Platelet-to- lymphocyte Ratio and Monocyte-to-lymphocyte Ratio in Melanoma Patients: A Cohort Study
In conclusion, baseline neutrophil-lymphocyte ratio, platelet-lymphocyte ratio and monocyte-lymphocyte ratio were identified as independent predictors for the prognosis of melanoma.PMID:38655656 | DOI:10.2340/actadv.v104.27571 (Source: Acta Dermato-Venereologica)
Source: Acta Dermato-Venereologica - April 24, 2024 Category: Dermatology Authors: S ümeyre Seda Ertekin Cristina Mangas Constanza Riquelme-Mc Loughlin Cristina Carrera Josep Malvehy Susana Puig Sebastian Podlipnik Source Type: research

Two New Strains of Drug-resistant Neisseria gonorrhoeae in a Bisexual Man having Sex with Men in Wroclaw, Poland
Acta Derm Venereol. 2024 Apr 24;104:adv35658. doi: 10.2340/actadv.v104.35658.NO ABSTRACTPMID:38655657 | DOI:10.2340/actadv.v104.35658 (Source: Acta Dermato-Venereologica)
Source: Acta Dermato-Venereologica - April 24, 2024 Category: Dermatology Authors: Martyna Bia ła Bartosz Pencakowski Beata M ączyńska Konrad Starzy ński Bartosz Szetela Source Type: research

Fixed Drug Eruption due to Dupilumab
Acta Derm Venereol. 2024 Apr 20;104:adv37804. doi: 10.2340/actadv.v104.37804.NO ABSTRACTPMID:38643361 | DOI:10.2340/actadv.v104.37804 (Source: Acta Dermato-Venereologica)
Source: Acta Dermato-Venereologica - April 21, 2024 Category: Dermatology Authors: Ayaka Kaneoka Natsuko Saito-Sasaki Yumiko Sakuragi Yu Sawada Source Type: research

Does Molluscum Contagiosum Need to be Managed Differently in Atopic Children?
Acta Derm Venereol. 2024 Apr 20;104:adv39983. doi: 10.2340/actadv.v104.39983.ABSTRACTThe association between molluscum contagiosum and concomitant atopic dermatitis and its impact on clinical features and treatment outcomes remains unclear. This retrospective study, conducted in the paediatric dermatology clinic of a tertiary medical centre, aimed to compare molluscum patients with and without atopic dermatitis. A total of 615 children with molluscum were included, 13.17% of whom had atopic dermatitis. While the latter group exhibited higher lesion count and itchiness (p=0.026 and p=0.044, respectively), no significant dif...
Source: Acta Dermato-Venereologica - April 21, 2024 Category: Dermatology Authors: Nicolas Andre Adva Alyagon Eman Jurban Khen Moscovici Amir Horev Source Type: research

Fixed Drug Eruption due to Dupilumab
Acta Derm Venereol. 2024 Apr 20;104:adv37804. doi: 10.2340/actadv.v104.37804.NO ABSTRACTPMID:38643361 | DOI:10.2340/actadv.v104.37804 (Source: Acta Dermato-Venereologica)
Source: Acta Dermato-Venereologica - April 21, 2024 Category: Dermatology Authors: Ayaka Kaneoka Natsuko Saito-Sasaki Yumiko Sakuragi Yu Sawada Source Type: research

Does Molluscum Contagiosum Need to be Managed Differently in Atopic Children?
Acta Derm Venereol. 2024 Apr 20;104:adv39983. doi: 10.2340/actadv.v104.39983.ABSTRACTThe association between molluscum contagiosum and concomitant atopic dermatitis and its impact on clinical features and treatment outcomes remains unclear. This retrospective study, conducted in the paediatric dermatology clinic of a tertiary medical centre, aimed to compare molluscum patients with and without atopic dermatitis. A total of 615 children with molluscum were included, 13.17% of whom had atopic dermatitis. While the latter group exhibited higher lesion count and itchiness (p=0.026 and p=0.044, respectively), no significant dif...
Source: Acta Dermato-Venereologica - April 21, 2024 Category: Dermatology Authors: Nicolas Andre Adva Alyagon Eman Jurban Khen Moscovici Amir Horev Source Type: research

Effects of a Brief Mindfulness-based Intervention in Patients with Psoriasis: A Randomized Controlled Trial
Acta Derm Venereol. 2024 Apr 19;104:adv18277. doi: 10.2340/actadv.v104.18277.ABSTRACTMindfulness is a special type of attention, namely focusing on the current moment in a non-judgmental manner. Extensive mindfulness-based interventions have been shown to have positive effects in patients with psoriasis. However, it is unclear whether brief (2-week) interventions are also beneficial. Therefore, the aim of this study was to investigate the effects of a 2-week mindfulness-based intervention in patients with psoriasis. Patients were randomly assigned to an experimental (treatment-as-usual + mindfulness-based intervention) or ...
Source: Acta Dermato-Venereologica - April 19, 2024 Category: Dermatology Authors: Markus Eckardt Laura Stadtmueller Christoph Zick J örg Kupfer Christina Schut Source Type: research

Effects of a Brief Mindfulness-based Intervention in Patients with Psoriasis: A Randomized Controlled Trial
Acta Derm Venereol. 2024 Apr 19;104:adv18277. doi: 10.2340/actadv.v104.18277.ABSTRACTMindfulness is a special type of attention, namely focusing on the current moment in a non-judgmental manner. Extensive mindfulness-based interventions have been shown to have positive effects in patients with psoriasis. However, it is unclear whether brief (2-week) interventions are also beneficial. Therefore, the aim of this study was to investigate the effects of a 2-week mindfulness-based intervention in patients with psoriasis. Patients were randomly assigned to an experimental (treatment-as-usual + mindfulness-based intervention) or ...
Source: Acta Dermato-Venereologica - April 19, 2024 Category: Dermatology Authors: Markus Eckardt Laura Stadtmueller Christoph Zick J örg Kupfer Christina Schut Source Type: research

Skin Cancer Risk of Narrow-Band UV-B (TL-01) Phototherapy: A Multi-Center Registry Study with 4,815 Patients
In conclusion, an increased incidence of skin cancers was observed among TL-01 treated patients. It should be confirmed in the future whether the skin cancer risk of TL-01 phototherapy will remain high in a longer follow-up.PMID:38629891 | DOI:10.2340/actadv.v104.39927 (Source: Acta Dermato-Venereologica)
Source: Acta Dermato-Venereologica - April 17, 2024 Category: Dermatology Authors: Petra Åkerla Eero Pukkala Mika Helminen Niina Korhonen Toni Karppinen Source Type: research

Patient Journey of Generalized Pustular Psoriasis: A Real-world Study Using Data-mining Methods and Japanese Claims Data
Acta Derm Venereol. 2024 Apr 17;104:adv11946. doi: 10.2340/actadv.v104.11946.NO ABSTRACTPMID:38629892 | DOI:10.2340/actadv.v104.11946 (Source: Acta Dermato-Venereologica)
Source: Acta Dermato-Venereologica - April 17, 2024 Category: Dermatology Authors: Koremasa Hayama Yahui Tian Ryoko Iwasaki Hideki Fujita Source Type: research

Nevus-associated Lentigo Maligna and Lentigo Maligna Melanoma, Clinicopathological Features
This study aimed to evaluate the frequency of NALMM and its clinicopathological features. A total of 201 histopathology reports were reviewed and among them 20% of the samples corresponded to NALMM, with females overrepresented in this group (p = 0.02). A significant association was also observed between NALMM with the presence of multiple nevi (p = 0.01), and dysplastic nevi (p = 0.04). Moreover, the risk of developing a second melanoma of nevus-associated type was 4.3 times higher in patients with NALMM. These results indicate that NALMM is more frequent than previously reported, suggesting that the associated nevus coul...
Source: Acta Dermato-Venereologica - April 17, 2024 Category: Dermatology Authors: Iara R T Drakensj ö Mari-Anne Hedblad Eugenia Col ón Cervantes Ada Girnita Source Type: research

Skin Cancer Risk of Narrow-Band UV-B (TL-01) Phototherapy: A Multi-Center Registry Study with 4,815 Patients
In conclusion, an increased incidence of skin cancers was observed among TL-01 treated patients. It should be confirmed in the future whether the skin cancer risk of TL-01 phototherapy will remain high in a longer follow-up.PMID:38629891 | DOI:10.2340/actadv.v104.39927 (Source: Acta Dermato-Venereologica)
Source: Acta Dermato-Venereologica - April 17, 2024 Category: Dermatology Authors: Petra Åkerla Eero Pukkala Mika Helminen Niina Korhonen Toni Karppinen Source Type: research

Patient Journey of Generalized Pustular Psoriasis: A Real-world Study Using Data-mining Methods and Japanese Claims Data
Acta Derm Venereol. 2024 Apr 17;104:adv11946. doi: 10.2340/actadv.v104.11946.NO ABSTRACTPMID:38629892 | DOI:10.2340/actadv.v104.11946 (Source: Acta Dermato-Venereologica)
Source: Acta Dermato-Venereologica - April 17, 2024 Category: Dermatology Authors: Koremasa Hayama Yahui Tian Ryoko Iwasaki Hideki Fujita Source Type: research

Nevus-associated Lentigo Maligna and Lentigo Maligna Melanoma, Clinicopathological Features
This study aimed to evaluate the frequency of NALMM and its clinicopathological features. A total of 201 histopathology reports were reviewed and among them 20% of the samples corresponded to NALMM, with females overrepresented in this group (p = 0.02). A significant association was also observed between NALMM with the presence of multiple nevi (p = 0.01), and dysplastic nevi (p = 0.04). Moreover, the risk of developing a second melanoma of nevus-associated type was 4.3 times higher in patients with NALMM. These results indicate that NALMM is more frequent than previously reported, suggesting that the associated nevus coul...
Source: Acta Dermato-Venereologica - April 17, 2024 Category: Dermatology Authors: Iara R T Drakensj ö Mari-Anne Hedblad Eugenia Col ón Cervantes Ada Girnita Source Type: research