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Targeted therapies in the treatment of GIST: Adverse events and maximising the benefits of sunitinib through proactive therapy management.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions. Imatinib and sunitinib are generally well tolerated with known and manageable AE profiles. Proactive therapy management strategies can enable treatment optimisation and allow patients to continue treatment with minimal interruption. PMID: 19900123 [PubMed - as supplied by publisher] (Source: Acta Oncologica)
Source: Acta Oncologica - November 10, 2009 Category: Cancer & Oncology Authors: Wolter P, Schöffski P Tags: Acta Oncol Source Type: journals

Stevens-Johnson syndrome following concurrent phenytoin and holocranial radiotherapy.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract. PMID: 19888894 [PubMed - as supplied by publisher] (Source: Acta Oncologica)
Source: Acta Oncologica - November 5, 2009 Category: Cancer & Oncology Authors: Goyal S, Biswas A, Puri T, Mohanti BK Tags: Acta Oncol Source Type: journals

Optimal beam arrangement for stereotactic body radiation therapy delivery in lung tumors.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion. Based on the dosimetric criteria outlined in RTOG 0236, the treatment technique using non-coplanar static beams showed the most preferable results for SBRT of lung lesions. PMID: 19888895 [PubMed - as supplied by publisher] (Source: Acta Oncologica)
Source: Acta Oncologica - November 5, 2009 Category: Cancer & Oncology Authors: Lim DH, Yi BY, Mirmiran A, Dhople A, Suntharalingam M, D'Souza WD Tags: Acta Oncol Source Type: journals

Separation and identification of differentially expressed nuclear matrix proteins in breast carcinoma forming.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Discussion.The proteins identified in this study may potentially prove to be useful markers for breast carcinoma diagnosis. PMID: 19878069 [PubMed - as supplied by publisher] (Source: Acta Oncologica)
Source: Acta Oncologica - November 2, 2009 Category: Cancer & Oncology Authors: He Q, Zhang SQ, Chu YL, Jia XL, Zhao LH, Wang XL Tags: Acta Oncol Source Type: journals

Additive endocrine therapy for advanced breast cancer - back to the future.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
While novel endocrine treatment options have been implemented in the advanced - as well as adjuvant setting, recent results suggest a place for "old-fashioned" additive treatment with estrogens in advanced breast cancer. This paper reviews the biological rationale for endocrine therapy in general and additive treatment with estrogens in particular. The finding that patients becoming resistant to treatment with aromatase inhibitors may subsequently respond to estrogen therapy adds important information to our understanding of therapy resistance in general. Moreover, the return of a therapeutic option abandoned more than...
Source: Acta Oncologica - October 31, 2009 Category: Cancer & Oncology Authors: Lønning PE Tags: Acta Oncol Source Type: journals

Physical activity for the affected limb and arm lymphedema after breast cancer surgery. A prospective, randomized controlled trial with two years follow-up.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION. Patients that undergo breast cancer surgery with axillary lymph node dissection should be encouraged to maintain physical activity in their daily lives without restrictions and without fear of developing ALE. PMID: 19863217 [PubMed - in process] (Source: Acta Oncologica)
Source: Acta Oncologica - October 31, 2009 Category: Cancer & Oncology Authors: Sagen A, Kåresen R, Risberg MA Tags: Acta Oncol Source Type: journals

Changes in arm morbidities and health-related quality of life after breast cancer surgery - a five-year follow-up study.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS. The overall HRQoL improved significantly from baseline to five years, despite the chronic arm pain and increase in ALE. Three independent predictive factors of HRQoL were identified. PMID: 19863218 [PubMed - in process] (Source: Acta Oncologica)
Source: Acta Oncologica - October 31, 2009 Category: Cancer & Oncology Authors: Sagen A, Kåresen R, Sandvik L, Risberg MA Tags: Acta Oncol Source Type: journals

An exploratory study of associations between illness perceptions and adjustment and changes after psychosocial rehabilitation in survivors of breast cancer.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This study indicates that illness perceptions are associated with adjustment; however, illness perceptions did not change after participation in a one-week multi-component rehabilitation course. PMID: 19863219 [PubMed - in process] (Source: Acta Oncologica)
Source: Acta Oncologica - October 31, 2009 Category: Cancer & Oncology Authors: Jørgensen IL, Frederiksen K, Boesen E, Elsass P, Johansen C Tags: Acta Oncol Source Type: journals

Prevalence of depression and its related factors among Chinese women with breast cancer.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION. Depression is common among Asian women with breast cancer. Routine screening and prevention of depression are warranted among women with breast cancer. PMID: 19863220 [PubMed - in process] (Source: Acta Oncologica)
Source: Acta Oncologica - October 31, 2009 Category: Cancer & Oncology Authors: Chen X, Zheng Y, Zheng W, Gu K, Chen Z, Lu W, Shu XO Tags: Acta Oncol Source Type: journals

The expression of p53, bcl-2, bax, fas and fasL in the primary tumour and lymph node metastases of breast cancer.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS. The expression of p53, bax, bcl - 2, fas and fasL is not maintained in the matching lymph node metastases of breast cancer. Large studies comparing the expression of relevant tumour biology factors in primary tumours and parallel lymph node metastases and their impact on therapy outcome, especially in the adjuvant setting, are warranted. PMID: 19863221 [PubMed - in process] (Source: Acta Oncologica)
Source: Acta Oncologica - October 31, 2009 Category: Cancer & Oncology Authors: Sjöström-Mattson J, Von Boguslawski K, Bengtsson NO, Mjaaland I, Salmenkivi K, Blomqvist C Tags: Acta Oncol Source Type: journals

Preoperative radiotherapy and extracellular matrix remodeling in rectal mucosa and tumour matrix metalloproteinases and plasminogen components.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS. This study indicates a radiation-induced effect on selected ECM remodeling proteases. This reaction may be responsible for early and late morbidity. Interference of this response might reduce these consequences. PMID: 19863222 [PubMed - in process] (Source: Acta Oncologica)
Source: Acta Oncologica - October 31, 2009 Category: Cancer & Oncology Authors: Angenete E, Oresland T, Falk P, Breimer M, Hultborn R, Ivarsson ML Tags: Acta Oncol Source Type: journals

The number of identified lymph node metastases increases continuously with increased total lymph node recovery in pT3 colon cancer.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This study aims to investigate the association between the total lymph node harvest and the number of lymph node metastases in colon cancer specimen. MATERIAL AND METHODS. We studied the original pathology reports of 649 patients diagnosed with T3 adenocarcinoma of the colon at the Department of Clinical Pathology and Genetics at Linköping University Hospital, Linköping, Sweden between the years 2000 and 2008. Patient demographics, specimen staging data, and lymph node recovery data were collected for each case. RESULTS. We found a positive association between the total lymph node harvest and the number of lymph ...
Source: Acta Oncologica - October 31, 2009 Category: Cancer & Oncology Authors: Törnroos A, Garvin S, Olsson H Tags: Acta Oncol Source Type: journals

Changes in cytokine and biomarker blood levels in patients with colorectal cancer during dendritic cell-based vaccination.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION. The increased levels of key pro-inflammatory cytokines in serum of patients who achieved stable disease following vaccination suggest the occurrence of vaccine-induced Th1 responses. Since Th1 responses seem to be essential in cancer immunotherapy this may indicate a therapeutic potential of the vaccine. PMID: 19863224 [PubMed - in process] (Source: Acta Oncologica)
Source: Acta Oncologica - October 31, 2009 Category: Cancer & Oncology Authors: Burgdorf SK, Claesson MH, Nielsen HJ, Rosenberg J Tags: Acta Oncol Source Type: journals

Synchronous and metachronous skeletal osteosarcomas: the Norwegian Radium Hospital experience.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions. The prognosis for patients with synchronous and metachronous skeletal osteosarcoma is poor. However, because long-term survival is seen, aggressive treatment to selected cases, e.g., patients with an osteosarcoma predisposing syndrome and/or late occurring metachronous tumours, is justified. Revealing a possible clonal relationship between these tumors, e.g., by karyotyping, may be of interest for estimating prognosis and guide therapy intensiveness. PMID: 19863225 [PubMed - in process] (Source: Acta Oncologica)
Source: Acta Oncologica - October 31, 2009 Category: Cancer & Oncology Authors: Brandal P, Bjerkehagen B, Bruland OS, Skjeldal S, Bogsrud TV, Hall KS Tags: Acta Oncol Source Type: journals

The role of cbl family of ubiquitin ligases in gastric cancer exosome-induced apoptosis of Jurkat T cells.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS. The Cbl family of ubiquitin ligases might be involved in regulation of exosome-induced apoptosis of Jurkat T cells by increasing PI3K proteasome degradation, inactivation of PI3K/Akt signaling, thus mediating some effects of caspase activation. PMID: 19863226 [PubMed - in process] (Source: Acta Oncologica)
Source: Acta Oncologica - October 31, 2009 Category: Cancer & Oncology Authors: Qu JL, Qu XJ, Qu JL, Qu XJ, Zhao MF, Teng YE, Zhang Y, Hou KZ, Jiang YH, Yang XH, Liu YP Tags: Acta Oncol Source Type: journals

Dose prescription and optimisation based on tumour hypoxia.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
DISCUSSION. The results have shown that highly heterogeneous dose distributions may lead to significant improvements of the outcome only for static oxygenations. In contrast, the proposed method that involves the segmentation of the dose distributions and the optimisation of the dose prescribed to each segment to account for local heterogeneity may lead to significantly improved local control for clinically-relevant patterns of oxygenation. The clinical applicability of the method is warranted by its relatively easy adaptation to functional imaging of tumour hypoxia obtained with markers with known uptake properties. P...
Source: Acta Oncologica - October 31, 2009 Category: Cancer & Oncology Authors: Toma-Daşu I, Daşu A, Brahme A Tags: Acta Oncol Source Type: journals

Quality assurance of volumetric modulated arc therapy using Elekta Synergy.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS. Quality assurance for prostate VMAT delivery has been performed with a satisfied result. PMID: 19863228 [PubMed - in process] (Source: Acta Oncologica)
Source: Acta Oncologica - October 31, 2009 Category: Cancer & Oncology Authors: Haga A, Nakagawa K, Shiraishi K, Itoh S, Terahara A, Yamashita H, Ohtomo K, Saegusa S, Imae T, Yoda K, Pellegrini R Tags: Acta Oncol Source Type: journals

Investigation of motion sickness and inertial stability on a moving couch for intra-fraction motion compensation.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
DISCUSSION. Among the 4800 responses, 95% were 1 (no discomfort) of 9, and there were no scores of 6 or higher. Mild discomfort (scores of 4-5) was similar during couch motion and before couch motion (p = 0.39). Mild discomfort was less common after couch motion (p = 0.039) than before or during couch movement. There was a near 1:1 correspondence between marker-pair regression coefficients and phase offset values during couch-stationary and couch-moving conditions. Our results show that patients do not suffer motion sickness or external surface instability on a moving couch. PMID: 19863229 [PubMed - in process] (Source: Acta Oncologica)
Source: Acta Oncologica - October 31, 2009 Category: Cancer & Oncology Authors: D'Souza WD, Malinowski KT, Van Liew S, D'Souza G, Asbury K, McAvoy TJ, Suntharalingam M, Regine WF Tags: Acta Oncol Source Type: journals

Neutropenia during adjuvant chemotherapy of breast cancer is not a predictor of outcome.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19863230 [PubMed - in process] (Source: Acta Oncologica)
Source: Acta Oncologica - October 31, 2009 Category: Cancer & Oncology Authors: Kumpulainen EJ, Hirvikoski PP, Johansson RT Tags: Acta Oncol Source Type: journals

First report on prostate displacements immediately before and after treatment relative to the position during VMAT delivery.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19863231 [PubMed - in process] (Source: Acta Oncologica)
Source: Acta Oncologica - October 31, 2009 Category: Cancer & Oncology Authors: Nakagawa K, Shiraishi K, Nakagawa K, Shiraishi K, Kida S, Haga A, Yamamoto K, Saegusa S, Terahara A, Itoh S, Ohtomo K, Yoda K Tags: Acta Oncol Source Type: journals

Badminton, rectal cancer and 25 kg weight gain during chemotherapy.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19863232 [PubMed - in process] (Source: Acta Oncologica)
Source: Acta Oncologica - October 31, 2009 Category: Cancer & Oncology Authors: Riklin C, Guntern D, Leyvraz S, Montemurro M Tags: Acta Oncol Source Type: journals

Second opinions: agendas and ego.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19863233 [PubMed - in process] (Source: Acta Oncologica)
Source: Acta Oncologica - October 31, 2009 Category: Cancer & Oncology Authors: Links M, Aghmesheh M Tags: Acta Oncol Source Type: journals

Hoarseness during treatment with bevacizumab and other vascular endothelial growth factor signalling inhibitors.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19863234 [PubMed - in process] (Source: Acta Oncologica)
Source: Acta Oncologica - October 31, 2009 Category: Cancer & Oncology Authors: Wong H, Yau T, Man CW, Epstein RJ Tags: Acta Oncol Source Type: journals

Uncommon long-term survival in a patient with chronic myeloid leukemia.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19863235 [PubMed - in process] (Source: Acta Oncologica)
Source: Acta Oncologica - October 31, 2009 Category: Cancer & Oncology Authors: Stagno F, Vigneri P, Stagno F, Vigneri P, Del Fabro V, Stella S, Berretta S, Massimino M, Tirrò E, Messina A, Di Raimondo F Tags: Acta Oncol Source Type: journals

Genetic variants in association studies--review of strengths and weaknesses in study design and current knowledge of impact on cancer risk.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Sequencing of the human genome has recently been completed and mapping of the complete genomic variation is ongoing. During the last decade there has been a huge expansion of studies of genetic variants, both with respect to association studies of disease risk and for studies of genetic factors of prognosis and treatments response, i.e., pharmacogenomics. The use of genetics to predict a patient's risk of disease or treatment response is one step toward an improved personalised prevention and screening modality for the prevention of cancer and treatment selection. The technology and statistical methods for completing w...
Source: Acta Oncologica - October 31, 2009 Category: Cancer & Oncology Authors: Andersson U, McKean-Cowdin R, Hjalmars U, Malmer B Tags: Acta Oncol Source Type: journals

Arm/shoulder problems in breast cancer survivors are associated with reduced health and poorer physical quality of life.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We examined demography, lifestyle, quality of life (QoL) and somatic morbidity in BCSs with and without ASPs. We also compared the associations of restricted shoulder abduction and lymphedema with QoL. Methods. We used a cross-sectional case-control design. A sample of 256 BCSs all with lymph node metastases were examined at a mean of 4.1 (SD 0.9) years post-surgery. Based on objective examinations and self-rating the sample were separated into 81 BCSs (32%) with definite ASP (ASP+ group) and 175 (68%) with minimal or no ASP (ASP- group). The self-rating contained among other schedules the Short Form-36 (SF-36) and the Kwa...
Source: Acta Oncologica - October 19, 2009 Category: Cancer & Oncology Authors: Nesvold IL, Fosså SD, Holm I, Naume B, Dahl AA Tags: Acta Oncol Source Type: journals

Second hematologic malignancies after ABVD: Two case reports and a retrospective study of 183 Hodgkin lymphoma patients.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19839917 [PubMed - as supplied by publisher] (Source: Acta Oncologica)
Source: Acta Oncologica - October 19, 2009 Category: Cancer & Oncology Authors: Leong C, Ngeow J, Tan I, Quek R, Tao M, Loh Y, Tan HC, Lim ST Tags: Acta Oncol Source Type: journals

A dose escalation study of docetaxel plus capecitabine in combination with oxaliplatin in patients with advanced solid tumors.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions. These results demonstrate that CAP, DOC and OX can be safely combined at clinically relevant doses and this regimen merits further evaluation. PMID: 19839918 [PubMed - as supplied by publisher] (Source: Acta Oncologica)
Source: Acta Oncologica - October 19, 2009 Category: Cancer & Oncology Authors: Amarantidis K, Xenidis N, Chelis L, Chiotis A, Tentes A, Chatzaki E, Kortsaris A, Polychronidis A, Karakitsos P, Kakolyris S Tags: Acta Oncol Source Type: journals

Gemcitabine and capecitabine in combination for advanced anthracycline and taxane pre-treated breast cancer patients: A phase II study.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Discussions. We investigated the value of the GC combination as a treatment for late stage breast cancer patients. Tumour progression was delayed and the treatment was well tolerated. We believe that the GC therapy can achieve meaningful palliation. PMID: 19839920 [PubMed - as supplied by publisher] (Source: Acta Oncologica)
Source: Acta Oncologica - October 19, 2009 Category: Cancer & Oncology Authors: Malmström A, Hansen J, Malmberg L, Carlsson L, Svensson JH, Ahlgren J, Ahlin C, Jansson T, Westberg R Tags: Acta Oncol Source Type: journals

An armed oncolytic adenovirus ZD55-IL-24 combined with ADM or DDP demonstrated enhanced antitumor effect in lung cancer.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion. ZD55-IL-24 combined with ADM demonstrates improved killing effects against lung tumor xenograft. PMID: 19734998 [PubMed - as supplied by publisher] (Source: Acta Oncologica)
Source: Acta Oncologica - September 3, 2009 Category: Cancer & Oncology Authors: Zhong S, Yu D, Wang Y, Qiu S, Wu S, Liu X Tags: Acta Oncol Source Type: journals

Cardiotoxicity induced by tyrosine kinase inhibitors.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions. Careful cardiac monitoring and assessment by a cardiologist throughout the course of treatment with those TKIs that exert cardiac toxic effect is of primary importance. PMID: 19734999 [PubMed - as supplied by publisher] (Source: Acta Oncologica)
Source: Acta Oncologica - September 3, 2009 Category: Cancer & Oncology Authors: Orphanos GS, Ioannidis GN, Ardavanis AG Tags: Acta Oncol Source Type: journals

Oncolytic adenovirus treatment of a patient with refractory neuroblastoma.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19735000 [PubMed - as supplied by publisher] (Source: Acta Oncologica)
Source: Acta Oncologica - September 3, 2009 Category: Cancer & Oncology Authors: Pesonen S, Helin H, Nokisalmi P, Escutenaire S, Ribacka C, Sarkioja M, Cerullo V, Guse K, Bauerschmitz G, Laasonen L, Kantola T, Ristimaki A, Rajecki M, Oksanen M, Haavisto E, Kanerva A, Joensuu T, Hemminki A Tags: Acta Oncol Source Type: journals

Hoarseness during treatment with bevacizumab and other vascular endothelial growth factor signalling inhibitors.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19722111 [PubMed - as supplied by publisher] (Source: Acta Oncologica)
Source: Acta Oncologica - August 30, 2009 Category: Cancer & Oncology Authors: Wong H, Yau T, Man CW, Epstein RJ Tags: Acta Oncol Source Type: journals

Are survival rates for Tyrol published in the Eurocare studies biased?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions. Evaluation of data quality in the Cancer Registry of Tyrol demonstrated that the survival rates published for Tyrol are only minimally biased by registration or analysis procedures. However, access to data on emigration, which until now is not possible because of data protection restrictions, would reduce the bias in patient survival status, bearing in mind that the extent of emigration of cancer patients is expected to increase in Austria over the coming years. PMID: 19714522 [PubMed - as supplied by publisher] (Source: Acta Oncologica)
Source: Acta Oncologica - August 26, 2009 Category: Cancer & Oncology Authors: Oberaigner W, Siebert U Tags: Acta Oncol Source Type: journals

A systematic review and meta-analysis of immunochemotherapy with rituximab for B-cell non-Hodgkin's lymphoma.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion. R-chemo is superior to chemotherapy alone in patients with B-cell non-Hodgkin's lymphoma, especially for diffuse large B-cell lymphoma and follicular lymphoma. PMID: 19714523 [PubMed - as supplied by publisher] (Source: Acta Oncologica)
Source: Acta Oncologica - August 26, 2009 Category: Cancer & Oncology Authors: Gao G, Liang X, Jiang J, Zhou X, Huang R, Chu Z, Zhan Q Tags: Acta Oncol Source Type: journals

Prevalence of depression and its related factors among Chinese women with breast cancer.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion. Depression is common among Asian women with breast cancer. Routine screening and prevention of depression are warranted among women with breast cancer. PMID: 19714524 [PubMed - as supplied by publisher] (Source: Acta Oncologica)
Source: Acta Oncologica - August 26, 2009 Category: Cancer & Oncology Authors: Chen X, Zheng Y, Zheng W, Gu K, Chen Z, Lu W, Shu XO Tags: Acta Oncol Source Type: journals

Dose prescription and optimisation based on tumour hypoxia.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Introduction. Tumour hypoxia is an important factor that confers radioresistance to the affected cells and could thus decrease the tumour response to radiotherapy. The development of advanced imaging methods that quantify both the extent and the spatial distribution of the hypoxic regions has created the premises to devise therapies that target the hypoxic regions in the tumour. Materials and methods. The present study proposes an original method to prescribe objectively dose distributions that focus the radiation dose to the radioresistant tumour regions and could therefore spare adjacent normal tissues. The effective...
Source: Acta Oncologica - August 26, 2009 Category: Cancer & Oncology Authors: Toma-Dasu I, Dasu A, Brahme A Tags: Acta Oncol Source Type: journals

Changes in arm morbidities and health-related quality of life after breast cancer surgery - a five-year follow-up study.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions. The overall HRQoL improved significantly from baseline to five years, despite the chronic arm pain and increase in ALE. Three independent predictive factors of HRQoL were identified. PMID: 19714526 [PubMed - as supplied by publisher] (Source: Acta Oncologica)
Source: Acta Oncologica - August 26, 2009 Category: Cancer & Oncology Authors: Sagen A, Kåresen R, Sandvik L, Risberg MA Tags: Acta Oncol Source Type: journals

Investigation of motion sickness and inertial stability on a moving couch for intra-fraction motion compensation.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Background. Respiration-induced tumor motion compensation using a treatment couch requires moving the patient at non-trivial speeds. The purpose of this work was to investigate motion sickness and stability of the patient's external surface due to a moving couch with respiration-comparable velocities and accelerations. Material and methods. A couch was designed to move with a peak-peak displacement of 5 cm and 1 cm in the S-I and A-P directions, respectively, and a period of 3.6 s. Fifty patients completed a 16-question motion sickness assessment questionnaire (MSAQ) prior to, during, and after the study. Seven optical...
Source: Acta Oncologica - August 26, 2009 Category: Cancer & Oncology Authors: D'Souza WD, Malinowski KT, Van Liew S, D'Souza G, Asbury K, McAvoy TJ, Suntharalingam M, Regine WF Tags: Acta Oncol Source Type: journals

Preoperative radiotherapy and extracellular matrix remodeling in rectal mucosa and tumour matrix metalloproteinases and plasminogen components.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions. This study indicates a radiation-induced effect on selected ECM remodeling proteases. This reaction may be responsible for early and late morbidity. Interference of this response might reduce these consequences. PMID: 19714528 [PubMed - as supplied by publisher] (Source: Acta Oncologica)
Source: Acta Oncologica - August 26, 2009 Category: Cancer & Oncology Authors: Angenete E, Oresland T, Falk P, Breimer M, Hultborn R, Ivarsson ML Tags: Acta Oncol Source Type: journals

Uncommon long-term survival in a patient with chronic myeloid leukemia.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19714529 [PubMed - as supplied by publisher] (Source: Acta Oncologica)
Source: Acta Oncologica - August 26, 2009 Category: Cancer & Oncology Authors: Stagno F, Vigneri P, Del Fabro V, Stella S, Berretta S, Massimino M, Tirro E, Messina A, Di Raimondo F Tags: Acta Oncol Source Type: journals

Sorafenib induces partial response in metastatic medullary thyroid carcinoma.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19711206 [PubMed - as supplied by publisher] (Source: Acta Oncologica)
Source: Acta Oncologica - August 25, 2009 Category: Cancer & Oncology Authors: Spector E, Franklin MJ, Truskinovsky AM, Dudek AZ Tags: Acta Oncol Source Type: journals

Interleukin-18 promoter polymorphism is associated with lung cancer: A case-control study.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Discussion. This is the first report to investigate the association between IL-18 polymorphism and lung cancer. Our results suggest that IL-18 polymorphism contributes to the lung cancer risk, particularly among SC patients. Further studies with larger numbers of patients are required to determine the possible association between IL-18 polymorphisms and different histological types of lung cancer. PMID: 19642044 [PubMed - as supplied by publisher] (Source: Acta Oncologica)
Source: Acta Oncologica - July 28, 2009 Category: Cancer & Oncology Authors: Farjadfar A, Mojtahedi Z, Ghayumi MA, Erfani N, Haghshenas MR, Ghaderi A Tags: Acta Oncol Source Type: journals

Quality assurance of volumetric modulated arc therapy using Elekta Synergy.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions. Quality assurance for prostate VMAT delivery has been performed with a satisfied result. PMID: 19639466 [PubMed - as supplied by publisher] (Source: Acta Oncologica)
Source: Acta Oncologica - July 28, 2009 Category: Cancer & Oncology Authors: Haga A, Nakagawa K, Shiraishi K, Itoh S, Terahara A, Yamashita H, Ohtomo K, Saegusa S, Imae T, Yoda K, Pellegrini R Tags: Acta Oncol Source Type: journals

A multimodality approach to reversible paraneoplastic encephalitis associated with ovarian teratomas.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19639467 [PubMed - as supplied by publisher] (Source: Acta Oncologica)
Source: Acta Oncologica - July 27, 2009 Category: Cancer & Oncology Authors: Tang T, Tay KY, Chai J, Agarwal A, Low J, Lee EL, Chuah KL, Sittampalan KS, Wong CF, Dalmau J, Ngeow J, Soh LT, Tan MH Tags: Acta Oncol Source Type: journals

Tumor-associated epilepsy and glioma: Are there common genetic pathways?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion. Genes involved in the immune response, in synaptic transmission and in cell cycle control are discussed that may play a role in the pathogenesis of tumor growth as well as epileptic symptoms in patients with gliomas. PMID: 19639468 [PubMed - as supplied by publisher] (Source: Acta Oncologica)
Source: Acta Oncologica - July 27, 2009 Category: Cancer & Oncology Authors: Berntsson SG, Malmer B, Bondy ML, Qu M, Smits A Tags: Acta Oncol Source Type: journals

Changes in cytokine and biomarker blood levels in patients with colorectal cancer during dendritic cell-based vaccination.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion. The increased levels of key pro-inflammatory cytokines in serum of patients who achieved stable disease following vaccination suggest the occurrence of vaccine-induced Th1 responses. Since Th1 responses seem to be essential in cancer immunotherapy this may indicate a therapeutic potential of the vaccine. PMID: 19636982 [PubMed - as supplied by publisher] (Source: Acta Oncologica)
Source: Acta Oncologica - July 26, 2009 Category: Cancer & Oncology Authors: Burgdorf SK, Claesson MH, Nielsen HJ, Rosenberg J Tags: Acta Oncol Source Type: journals

Does enhanced information at cancer genetic counseling improve counselees' knowledge, risk perception, satisfaction and negotiation of information to at-risk relatives? - a randomized study.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion. Apparently, the current genetic counseling is managed properly and extended information does not seem necessary in all cases. However, some counselees need additional sessions. PMID: 19636983 [PubMed - as supplied by publisher] (Source: Acta Oncologica)
Source: Acta Oncologica - July 26, 2009 Category: Cancer & Oncology Authors: Roshanai AH, Rosenquist R, Lampic C, Nordin K Tags: Acta Oncol Source Type: journals

Somatic mutation of PIK3R1 gene is rare in common human cancers.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19634059 [PubMed - as supplied by publisher] (Source: Acta Oncologica)
Source: Acta Oncologica - July 25, 2009 Category: Cancer & Oncology Authors: Park SW, Kang MR, Eom HS, Han JY, Ahn CH, Kim SS, Lee SH, Yoo NJ Tags: Acta Oncol Source Type: journals

Change in diffusion weighted MRI during liver cancer radiotherapy: Preliminary observations.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions. Changes in tumour ADC were seen during RT. Larger increases were correlated with higher doses and increased likelihood of response. PMID: 19634060 [PubMed - as supplied by publisher] (Source: Acta Oncologica)
Source: Acta Oncologica - July 25, 2009 Category: Cancer & Oncology Authors: Eccles CL, Haider EA, Haider MA, Fung S, Lockwood G, Dawson LA Tags: Acta Oncol Source Type: journals