Acta Oto-LaryngologicaThis is an RSS file. You can use it to subscribe to this data in your favourite RSS reader, such as GoogleReader, or to display this data on your own website or blog. Subscribe to this data using MyMedWorm.Subscribe to this data using GoogleReader.Subscribe to this data using Bloglines.Subscribe to this data using MyYahoo.

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Prevalence of allergic rhinitis among the adult population in Turkey.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: The prevalence of self-reported and physician-diagnosed allergic rhinitis (AR) exhibits significant variability across the seven geographical regions in Turkey. Our findings may contribute to the formulation of public health policy and development of preventive and therapeutic strategies for AR in Turkey. Objective: The purpose of this study was to assess the prevalence of AR in the Turkish adult population, with emphasis on descriptive parameters in seven distinct geographical regions in Turkey. Methods: The volunteers were evaluated with a custom-designed questionnaire for AR. Sample size for the study was ca...
Source: Acta Oto-Laryngologica - November 17, 2009 Category: ENT & OMF Authors: Cingi C, Topuz B, Songu M, Kara CO, Ural A, Yaz A, Yildirim M, Miman MC, Bal C Tags: Acta Otolaryngol Source Type: journals

Prognosis of sudden low-tone loss other than acute low-tone sensorineural hearing loss.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: In clinical practice, sudden low-tone loss other than acute low-tone sensorineural hearing loss (ALHL) shows a potential for recurrence. Objective: ALHL is often associated with recurrence and/or progression to Ménière's disease. We examined the prognosis of patients with sudden low-tone loss who were not classified in the audiometric definition of ALHL. Methods: Sixty-three patients diagnosed at the university hospital with idiopathic sudden low-tone loss of sensorineural hearing loss and without subjective vertigo were followed up in the long term with a mean of over 4 years. The rates of recurrence...
Source: Acta Oto-Laryngologica - November 17, 2009 Category: ENT & OMF Authors: Fushiki H, Junicho M, Kanazawa Y, Aso S, Watanabe Y Tags: Acta Otolaryngol Source Type: journals

A new coordinates system for cranial organs using magnetic resonance imaging.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion. We developed a new coordinates system for magnetic resonance imaging (MRI) that utilizes the labyrinth and eyeballs as references to measure the spatial arrangement of cranial organs, and we verified its usefulness by observing small structures in the labyrinth in 39 ears from 33 patients. Our new coordinates system could be used for stereotactic analysis of cranial organs in MRI. Objectives. To research semicircular canal anatomy in healthy organisms, we propose a method that employs references visible on MRI for stereotactic measurement of cranial structures, and we evaluated the usefulness of our method. Met...
Source: Acta Oto-Laryngologica - November 17, 2009 Category: ENT & OMF Authors: Suzuki K, Masukawa A, Aoki S, Arai Y, Ueno E Tags: Acta Otolaryngol Source Type: journals

3D-FLAIR MRI in facial nerve paralysis with and without audio-vestibular disorder.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: Among patients with facial nerve paralysis, significant difference was observed on three-dimensional fluid-attenuated inversion recovery magnetic resonance imaging (3D-FLAIR MRI) between those with and without audio-vestibular disturbance. This MRI technique may contribute to elucidation of the pathology of Ramsay Hunt syndrome and Bell's palsy. Objective: To evaluate the 3D-FLAIR MRI findings in patients who have facial nerve paralysis with and without audio-vestibular disturbance. Methods: 3D-FLAIR MRI was performed with and without gadolinium enhancement in 15 patients (5 men and 10 women) with unilateral fa...
Source: Acta Oto-Laryngologica - November 17, 2009 Category: ENT & OMF Authors: Nakata S, Mizuno T, Naganawa S, Sugiura M, Yoshida T, Teranishi M, Sone M, Nakashima T Tags: Acta Otolaryngol Source Type: journals

Acute dysphagia associated with aortic dissection: a case report and review of the literature.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report on a 58-year-old otherwise healthy male patient who presented with acute-onset intermittent dysphagia, mild dyspnea, and chest symptoms. He was referred to an emergency ENT unit for a suspected peritonsillar abscess but died of a massive aortic dissection and cardiac tamponation a few hours later. This rare condition is discussed in the differential diagnosis of adult acute-onset dysphagia. PMID: 19916899 [PubMed - as supplied by publisher] (Source: Acta Oto-Laryngologica)
Source: Acta Oto-Laryngologica - November 17, 2009 Category: ENT & OMF Authors: Perheentupa U, Kinnunen I, Kujari H, Grénman R, Mäkitie AA Tags: Acta Otolaryngol Source Type: journals

The intravestibular source of the vestibular aqueduct. II: Its structure and function clarified by a developmental study of the intra-skeletal channels of the otic capsule.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: A developmental histologic study of the otic capsule indicates that it grows a system of lamellar bone with abundant interconnecting intraosseous channels. These include the 'cartilage canals' in the cartilage model, the chondro-osseous and Haversian-like (Volkmann's) canals in the ossified otic capsule, the fissula ante fenestram, which seems to function as a lifelong manufacturer of the latter two channels, and the inner layer (vestibular arch) of the vestibular aqueduct, which is a complex series of Volkmann's canals and microcanals. Chemical changes, possibly produced by breakdown of cells within the channe...
Source: Acta Oto-Laryngologica - November 7, 2009 Category: ENT & OMF Authors: Michaels L, Soucek S, Linthicum F Tags: Acta Otolaryngol Source Type: journals

Association between polymorphisms in SOD1 and noise-induced hearing loss in Chinese workers.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: SOD1 is an important gene related to noise-induced hearing loss (NIHL), and its effect is dependent on noise exposure levels. Objectives: To test whether the polymorphisms in the CuZn-superoxide dismutase gene (SOD1) are associated with susceptibility to NIHL in the Chinese population. Methods: Audiometric data from 2400 Chinese Han people exposed to occupational noise were analyzed. DNA samples were collected from the 10% most susceptible and the 10% most resistant individuals. Four SNPs in the introns of SOD1 were genotyped and their effects and interactions with noise exposure were analyzed. Results: Genotyp...
Source: Acta Oto-Laryngologica - November 7, 2009 Category: ENT & OMF Authors: Liu YM, Li XD, Guo X, Liu B, Lin AH, Rao SQ Tags: Acta Otolaryngol Source Type: journals

Three-dimensional reconstruction of the otosclerotic focus.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: The location and three-dimensional (3D) shapes of the otosclerotic foci suggest a general centripetal distribution of otosclerotic bone remodeling around the inner ear space, whereas the normal bone remodeling is distributed centrifugally. The existence of an inverse spatial relation between normal and otosclerotic bone remodeling suggests that inner ear mechanisms in control of bone remodeling may have a pathogenetic role in otosclerosis. Objectives: To explore the 3D shape of otosclerotic lesions around the inner ear space by introducing the use of 3D reconstructions and to discuss the results in a new conte...
Source: Acta Oto-Laryngologica - November 7, 2009 Category: ENT & OMF Authors: Bloch SL, Sørensen MS Tags: Acta Otolaryngol Source Type: journals

The association between gene polymorphisms in uncoupling proteins and hearing impairment in Japanese elderly.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: This study illustrates that UCP2 Ala55Val polymorphisms exhibit a significant association with age-related hearing loss in the Japanese population. Objectives: Mitochondrial uncoupling proteins (UCPs) have been suggested to play a protective role against neuron oxidative damage and a thermal signaling role in neuron modulation in the inner ear. In the current study, we examined the relationship between gene polymorphisms in UCP1 and UCP2 and hearing impairment (HI) in Japanese elderly. Methods: A total of 1547 subjects aged 40-79 years and living in Aichi prefecture, Japan, were entered into this study. Subject...
Source: Acta Oto-Laryngologica - November 7, 2009 Category: ENT & OMF Authors: Sugiura S, Uchida Y, Nakashima T, Ando F, Shimokata H Tags: Acta Otolaryngol Source Type: journals

Cochlear pathology in human temporal bones with otitis media.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: Middle and inner ear interactions in otitis media can lead to cochlear pathology. More severe pathological changes observed in the basal turn of the cochlea are consistent with prevalence of sensorineural hearing loss at higher frequencies in patients with otitis media. Methods: Of 614 temporal bones with otitis media, 47 with chronic and 35 with purulent otitis media were selected following strict exclusion of subjects with a history of acoustic trauma, head trauma, ototoxic drugs, and other diseases affecting the cochlear labyrinth. Temporal bones with labyrinthine inflammatory changes were further evaluated ...
Source: Acta Oto-Laryngologica - November 7, 2009 Category: ENT & OMF Authors: Joglekar S, Morita N, Cureoglu S, Schachern PA, Deroee AF, Tsuprun V, Paparella MM, Juhn SK Tags: Acta Otolaryngol Source Type: journals

Clinical phase I/feasibility study of the next generation indwelling Provox voice prosthesis (Provox Vega).Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Provox Vega prostheses demonstrate good short-term feasibility, and their optimized airflow-resistance design offers laryngectomy patients indwelling voice prostheses with more choices in outer diameters without sacrificing (too) much in voice quality. Objectives: Technological progress enables improvement of in vitro airflow characteristics of voice prostheses and design of voice prostheses with smaller outer diameters. This could potentially improve voice quality in users of Provox2, and avoid diminished voice quality in users of prostheses with smaller outer diameters. Methods: This was a prospective clinic...
Source: Acta Oto-Laryngologica - November 7, 2009 Category: ENT & OMF Authors: Hilgers FJ, Ackerstaff AH, van Rossum M, Jacobi I, Balm AJ, Bing Tan I, van den Brekel MW Tags: Acta Otolaryngol Source Type: journals

A new cochlear implant electrode design for preservation of residual hearing: a temporal bone study.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Success in conservation of residual hearing after cochlear implantation has benefited patients with high levels of residual low frequency hearing who were not previously considered for conventional cochlear implantation. Technological developments play a key role in minimizing trauma to the cochlea during placement of electrodes. Objectives: The Nucleus(R) Straight Research Array (SRA) has been designed and developed as a collaboration project between our centre and Cochlear Ltd with the objective of minimizing trauma to the cochlea with insertion of the electrode via the round window. Methods: We studied 22 f...
Source: Acta Oto-Laryngologica - November 2, 2009 Category: ENT & OMF Authors: Skarzynski H, -Fayette RP Tags: Acta Otolaryngol Source Type: journals

Vestibular neuritis: recurrence and incidence of secondary benign paroxysmal positional vertigo.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Recurrence of vestibular neuritis (VN) is a rare event in long-term follow-up. The incidence of benign paroxysmal positional vertigo (BPPV) in VN patients represents a quite common outcome. To our knowledge, this study represents the only long-term longitudinal study on recurrence of VN and incidence of secondary BPPV in VN. Objectives: To study a large number of VN patients longitudinally to identify the recurrence rate of VN and incidence of BPPV, other peripheral vestibular disorders, sudden hearing loss or Bell's palsy. Methods: This prospective cohort study assessed a VN patient-based clinic population. A...
Source: Acta Oto-Laryngologica - November 2, 2009 Category: ENT & OMF Authors: Mandalà M, Santoro GP, Awrey J, Nuti D Tags: Acta Otolaryngol Source Type: journals

Improved prognosis for localized malignant lymphomas of the head and neck.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: In this study we found localized malignant lymphomas of the head and neck to be highly treatable and to have a significantly improved prognosis with recent treatment methods. The head and neck surgeon should keep in mind that the prognosis, especially for diffuse large B-cell lymphoma, has improved if the patient receives the optimal treatment. Objectives: The purpose of this study was to ascertain the current prognosis of localized malignant lymphoma of the head and neck given recent advancements in treatment and diagnostic features, as well as adding histological subtypes to the literature according to the 20...
Source: Acta Oto-Laryngologica - November 2, 2009 Category: ENT & OMF Authors: Aanaes K, Kristensen E, Ralfkiær EM, von Buchwald C, Specht L Tags: Acta Otolaryngol Source Type: journals

Digital volume tomography (DVT) measurements of the olfactory cleft and olfactory fossa.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: Preoperative imaging is important, because of the small size of the cribriform plate, different anatomical variants of the olfactory fossa in varied patients and unequal width of the cribriform plate in the anterior and posterior third. Objective: Digital volume tomography (DVT) is a rather new imaging technique for the diagnosis of diseases of paranasal sinuses. This technology is dedicated to the evaluation of the distinctive structures of the anterior skull base due to the high resolution of the DVT. Based on the Keros classification this anatomic area was analyzed radiologically and also in relation to the ...
Source: Acta Oto-Laryngologica - November 2, 2009 Category: ENT & OMF Authors: Savvateeva DM, Güldner C, Murthum T, Bien S, Teymoortash A, Werner JA, Bremke M Tags: Acta Otolaryngol Source Type: journals

Postural stability during visual stimulation and the contribution from the vestibular apparatus.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: When combined with vestibular dysfunction, visual flow can exacerbate reductions in postural stability. This effect may be one of the mechanisms underlying visual vertigo, which can be evaluated using frequency analysis of body sway elicited by optokinetic stimulation (OKS). Objective: To clarify the interaction between the postural responses to visual flow and to input from the vestibular apparatus as a mediator of visual vertigo. Methods: Horizontal and vertical OKS with a stable fixation target were presented to 14 healthy subjects and 38 peripheral vestibular patients standing in a Romberg's posture, and th...
Source: Acta Oto-Laryngologica - November 2, 2009 Category: ENT & OMF Authors: Tsutsumi T, Murakami M, Kawaishi J, Chida W, Fukuoka Y, Watanabe K Tags: Acta Otolaryngol Source Type: journals

Localization of the sentinel lymph node in tongue VX2 carcinoma via indirect CT lymphography combined with methylene blue dye injection.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Indirect computed tomography lymphography (CT-LG) combined with blue dye injection can locate the sentinel lymph node (SLN) in tongue carcinoma. Objective: To localize the SLN in tongue VX2 carcinoma using indirect CT-LG combined with methylene blue injection. Methods: Eighteen rabbits were placed into three groups: metastasis, hyperplasia, and control. Indirect CT-LG was performed with an iohexol injection into the tongue submucosa. CT images were acquired at 1, 5, and 15 min after injection. Methylene blue was injected into the same area 24 h after indirect CT-LG, followed by SLN identification and histopath...
Source: Acta Oto-Laryngologica - November 2, 2009 Category: ENT & OMF Authors: Wu H, Ying H, Xi X, Shen N, Shu Y, Hoffman MR, Rieves A, Sha Y, Zhou L Tags: Acta Otolaryngol Source Type: journals

Vestibular schwannoma with absent vestibular evoked myogenic potentials to clicks but normal ABR, caloric responses and vestibular evoked myogenic potentials to 500 Hz tone bursts.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report a case of vestibular schwannoma with absent vestibular evoked myogenic potentials (VEMPs) to clicks but normal auditory brainstem responses, caloric responses, and vestibular evoked myogenic potentials to 500 Hz tone bursts. This patient visited our clinic with complaint of sudden right hearing loss. This was the third episode of hearing loss in his right ear. Due to atypical medical history, he underwent further neuro-otological and neuroradiological examinations. Among the neurophysiological tests, only VEMPs to clicks showed abnormal findings (absent responses on the right). MRI revealed a small vestibular sch...
Source: Acta Oto-Laryngologica - November 2, 2009 Category: ENT & OMF Authors: Murofushi T, Takehisa M Tags: Acta Otolaryngol Source Type: journals

A modified septoplasty with three high tension lines resection.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: The modified septoplasty with three tension lines resection is an effective and well-tolerated procedure, which can improve the objective and subjective outcomes, and provide a good approach that is applicable for various septal deviations, especially caudal deviation. Objectives: According to the biomechanics of the septal deviation, a modified septoplasty with three high tension lines resection was redefined. The purpose of this study was to review the surgical technique and objective and subjective outcomes. Methods: A retrospective review was conducted to identify patients undergoing septoplasty between 200...
Source: Acta Oto-Laryngologica - November 2, 2009 Category: ENT & OMF Authors: Wang T, Han D, Zhang L, Zang H, Li Y, Liu C Tags: Acta Otolaryngol Source Type: journals

Imaging of cochlear implant electrode array with flat-detector CT and conventional multislice CT: comparison of image quality and radiation dose.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: Cochlear implantation assessment is possible using commercially available standard flat-detector computed tomography (FD-CT) protocols. Image quality is superior to multislice CT (MSCT). The radiation dose of FD-CT is lower in comparison with MSCT standard protocols and may therefore overcome the limitations of MSCT in the evaluation of cochlear implants. PMID: 19883180 [PubMed - as supplied by publisher] (Source: Acta Oto-Laryngologica)
Source: Acta Oto-Laryngologica - November 2, 2009 Category: ENT & OMF Authors: Struffert T, Hertel V, Kyriakou Y, Krause J, Engelhorn T, Schick B, Iro H, Hornung J, Doerfler A Tags: Acta Otolaryngol Source Type: journals

Endogenous protection against oxidative stress caused by cisplatin: role of superoxide dismutase.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: The administration of cisplatin induces the activation of superoxide dismutase (SOD) as a response to oxidative stress in the cochleae of Sprague-Dawley rats and this activation is proportional to the activation of the intrinsic pathway of apoptosis. Objectives: To determine the role of the antioxidant endogenous mechanism in the preservation of cochlear integrity and function in an experimental model of cisplatin ototoxicity. Methods: Sixteen Sprague-Dawley rats were studied at 7 days after intraperitoneal injection of CDDP (n = 8) or 10 ml/kg NaCl 0.9% w/v in the control group (n = 8) by means of auditory ste...
Source: Acta Oto-Laryngologica - November 2, 2009 Category: ENT & OMF Authors: González-García JA, Nevado J, García-Berrocal JR, Sánchez-Rodríguez C, Trinidad A, Sanz R, Ramírez-Camacho R Tags: Acta Otolaryngol Source Type: journals

Moderately differentiated neuroendocrine carcinoma of the larynx.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Laryngeal moderately differentiated neuroendocrine carcinoma (LMDNEC) is an aggressive and uncommon malignancy. Thorough histological evaluation is the key to correct diagnosis and differentiation. Complete surgical resection of laryngeal primary lesions and suitable neck dissection of cervical nodes provide reasonable therapy, and postoperative radiotherapy should also be considered. Objective: To explore the diagnosis and treatment of LMDNEC. Methods: Clinical information regarding patient, presentation, immunohistochemical results, treatment, and outcome was obtained through review of patients' charts. Foll...
Source: Acta Oto-Laryngologica - November 2, 2009 Category: ENT & OMF Authors: Zhang M, Zhou L, Li C, Huang WT, Li XM Tags: Acta Otolaryngol Source Type: journals

Hearing and vestibular functions after plugging surgery for the posterior semicircular canal.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: Results of audiometry, caloric testing and vestibular evoked myogenic potential (VEMP) testing were hardly influenced by plugging surgery. OBJECTIVE: To evaluate the influence of surgical plugging of the posterior semicircular canal on inner ear function in patients with benign paroxysmal positional vertigo (BPPV). SUBJECTS AND METHODS: The subjects were five consecutive patients with intractable BPPV who underwent plugging surgery. The following functions of the inner ear were examined before and 6 months after surgery. Cochlea function was evaluated by the average hearing level of three frequencies (500, 100...
Source: Acta Oto-Laryngologica - October 31, 2009 Category: ENT & OMF Authors: Seo T, Hashimoto M, Saka N, Sakagami M Tags: Acta Otolaryngol Source Type: journals

An animal model of cochlear implantation with an intracochlear fluid delivery system.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: An animal model of cochlear implantation with a local intracochlear fluid through a microcatheter included in the array has been developed. It is suitable for evaluation of putative therapeutic agents to decrease cochlear trauma after cochlear implantation. OBJECTIVES: The purpose of this study was to design an animal model of cochlear implantation with an intracochlear fluid delivery system to demonstrate the stability of the device and study the patterns of hearing loss. MATERIALS AND METHODS: Eleven guinea pigs were implanted with a prototype array that comprised one electrode and a microcatheter connected t...
Source: Acta Oto-Laryngologica - October 31, 2009 Category: ENT & OMF Authors: Nguyen Y, Couloigner V, Rudic M, Nguyen Y, Couloigner V, Rudic M, Grayeli AB, Ferrary E, Sterkers O Tags: Acta Otolaryngol Source Type: journals

Utility of immunologic parameters in the evaluation of Meniere's disease.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: Because of the lack of association between a positive test and response to corticosteroid treatment, at present, detection of anti-HSP 70 antibody, tumor necrosis factor (TNF)-alpha, erythrocyte sedimentation rate (ESR), or antinuclear antibody (ANA), does not offer clinically useful information in the treatment of Meniere's disease (MD). OBJECTIVES: The study was designed to investigate the performance of various laboratory tests, including anti-HSP 70, TNF-alpha, ESR, ANA, and anti-phospholipid antibodies, in the diagnosis and treatment response of patients with MD. PATIENTS AND METHODS: Thirty patients who p...
Source: Acta Oto-Laryngologica - October 31, 2009 Category: ENT & OMF Authors: Süslü N, Yilmaz T, Gürsel B Tags: Acta Otolaryngol Source Type: journals

Assessment of the reuniting duct by three-dimensional CT rendering.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: The rendering strategy sometimes induces misunderstanding of the image. We demonstrated a more accurate image of the bony groove of the reuniting duct using three-dimensional (3D) cone beam CT image, which was less affected by artifacts created by the rendering effect. OBJECTIVE: To obtain a suitable image of the groove of the reuniting duct for future morphological study. MATERIALS AND METHODS: The grooves of reuniting ducts in 10 healthy human subjects were analyzed by cone beam CT in comparison with a cadaver study. RESULTS: We could obtain more accurate 3D CT images of the bony groove in human subjects by c...
Source: Acta Oto-Laryngologica - October 31, 2009 Category: ENT & OMF Authors: Yamane H, Takayama M, Sunami K, Sakamoto H, Inoue Y, Anniko M Tags: Acta Otolaryngol Source Type: journals

Endolymphatic space imaging in patients with delayed endolymphatic hydrops.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: Magnetic resonance imaging (MRI) after intratympanic gadolinium injection can reveal endolymphatic hydrops (ELH) in patients with delayed ELH (DELH). Patients with contralateral DELH may have bilateral ELH. OBJECTIVE: DELH has previously been diagnosed based on clinical history, hearing and vestibular examinations. DELH is classified into three types: ipsilateral, contralateral and bilateral indicate the side with the longstanding hearing loss. Ipsilateral DELH occurs in the ear with a profound hearing loss, contralateral DELH in the better hearing ear and bilateral DELH in both ears. Imaging diagnosis of the e...
Source: Acta Oto-Laryngologica - October 31, 2009 Category: ENT & OMF Authors: Kasai S, Teranishi M, Katayama N, Sugiura M, Nakata S, Sone M, Naganawa S, Nakashima T Tags: Acta Otolaryngol Source Type: journals

Estrogen receptors in the inner ear during different stages of pregnancy and development in the rat.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: ERalpha and ERbeta are present in the inner ear and are up- and down-regulated depending on the stage of maturation, development and pregnancy, suggesting that estrogen may have an effect on the cochlea during various stages of life. No estrogen receptors (ERs) were found in the cochlea of the developing fetus, which suggests that estrogen does not have an effect on the cochlea during gestation. OBJECTIVE: To investigate the distribution of ERs in the cochlea during pregnancy, maturation and development in a female rat model. MATERIALS AND METHODS: The cochleas of 24 rats in 4 groups in different time periods o...
Source: Acta Oto-Laryngologica - October 31, 2009 Category: ENT & OMF Authors: Simonoska R, Stenberg A, Masironi B, Sahlin L, Hultcrantz M Tags: Acta Otolaryngol Source Type: journals

Pressure changes in the human middle ear without opening the eustachian tube.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: By means of a direct, though non-invasive experiment on healthy humans we could demonstrate that middle ear (ME) pressure decreases when the eustachian tube (ET) does not open. Thus with a very simple method the basic theory of continuous gas loss from the ME into the circulation and the replenishment of the loss through the ET could be validated. OBJECTIVES: To record changes in ME pressure over a period of time in normal human ears, while the ET is kept closed. SUBJECTS AND METHODS: On-line tympanometry was carried out in three subjects, who refrained from swallowing for 20-120 min. RESULTS: During the time w...
Source: Acta Oto-Laryngologica - October 31, 2009 Category: ENT & OMF Authors: Pau HW, Sievert U, Just T, Sadé J Tags: Acta Otolaryngol Source Type: journals

The imbalance of enzymatic antioxidants in cholesteatoma.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: Depletion of enzymatic antioxidants was observed in cholesteatoma. However, a relationship between activity of enzymatic antioxidants and the extent of bone erosion was not found. OBJECTIVES: To measure the level of major enzymatic antioxidants in cholesteatoma, and to investigate the relationship between the level of enzymatic antioxidants and the extent of bone erosion. PATIENTS AND METHODS: The cholesteatoma and skin samples were obtained during otologic surgeries. All cases were grouped according to the number of bone erosion sites. Samples were examined biochemically and the levels of enzymatic antioxidant...
Source: Acta Oto-Laryngologica - October 31, 2009 Category: ENT & OMF Authors: Eskiizmir G, Yuceturk AV, Onur E, Var A, Temiz P Tags: Acta Otolaryngol Source Type: journals

Acute tympanic membrane perforations and the early immunological response in rats.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: This study showed that macrophages, B cells, and T cells occurred at different frequencies, localizations, and times after acute laser tympanic membrane perforation. Immunological cells were most prevalent in the proliferative mass adjacent to the annulus region. The cellular immunological response in freshly perforated eardrums was unexpectedly aggressive. OBJECTIVES: To study the occurrence of immunocompetent cells during the healing process of fresh perforated tympanic membranes. The information could be used to develop alternative outpatient procedures in the cure of chronic perforations, replacing convent...
Source: Acta Oto-Laryngologica - October 31, 2009 Category: ENT & OMF Authors: Aissa JT, Hultcrantz M Tags: Acta Otolaryngol Source Type: journals

Vestibular evoked myogenic potentials of children with inner ear malformations before and after cochlear implantation.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: Our results show that among the patients with inner ear malformations, there were two patients with sensory cells of sacculus and inferior vestibular neurons and at least five patients with inferior vestibular neurons only, but no patients without sensory cells and vestibular neurons, as determined on the basis of vestibular evoked myogenic potentials (VEMPs). OBJECTIVE: The aim of this study was to investigate whether sensory cells of sacculus or inferior vestibular neurons or both are present in cochlear implant patients with inner ear malformations, particularly common cavity (CC) deformity, using VEMPs. PA...
Source: Acta Oto-Laryngologica - October 31, 2009 Category: ENT & OMF Authors: Jin Y, Shinjo Y, Akamatsu Y, Yamasoba T, Kaga K Tags: Acta Otolaryngol Source Type: journals

Vestibular evoked myogenic potentials in chronic otitis media before and after surgery.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: The pathology of chronic otitis media (COM) could delay and reduce the energy transfer of sound to the inner ear. The significant improvement of postoperative vestibular evoked myogenic potential (VEMP) response rate and p13 latencies in the group of patients with no or negative postoperative ABG gain provided evidence that the sound energy inducing a VEMP might be different from the energy producing the auditory perception. OBJECTIVE: To evaluate the VEMP in patients with COM before and after surgery. SUBJECTS AND METHODS: Twenty-four subjects with unilateral COM were enrolled. A pure tone audiogram and VEMP u...
Source: Acta Oto-Laryngologica - October 31, 2009 Category: ENT & OMF Authors: Wang MC, Liu CY, Yu EC, Wu HJ, Lee GS Tags: Acta Otolaryngol Source Type: journals

Effect of topical use of mitomycin C and 5-fluorouracil on the closure time of myringotomies created by radiofrequency unit.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: Both mitomycin C (MC) and 5-fluorouracil (5-FU) had a significant effect in prolonging the patency rate of radiofrequency myringotomy. OBJECTIVE: To compare the effect of topical use of MC and 5-FU on the closure time of myringotomies created by a radiofrequency unit. MATERIALS AND METHODS: Myringotomies were performed using a radiofrequency unit on 80 tympanic membranes of 40 rats. Rats were divided into two study groups and one control group. MC (0.4 mg/ml) and 5-FU (50 mg/ml) pledgets were applied topically in the right ears (study groups, 20 ears each) for 10 min and saline pledgets in the left ears (contro...
Source: Acta Oto-Laryngologica - October 31, 2009 Category: ENT & OMF Authors: Baylancicek S, Sari M, Tutkun A Tags: Acta Otolaryngol Source Type: journals

Bedside therapeutic experiences with horizontal canal benign paroxysmal positional vertigo (cupulolithiasis).Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: After forced prolonged position type one (FPP-one) and the appropriate repositioning maneuvers, or FPP-two, 95.45% of patients with cupulolithiasis of the horizontal semicircular canal benign paroxysmal positional vertigo (HSC-BPPV).were symptom-free. OBJECTIVES: To treat patients with cupulolithiasis of the HSC-BPPV. SUBJECTS AND METHODS: This was a prospective study including 22 subjects with HSC-BPPV (cupulolithiasis) based on apogeotropic direction-changing positional nystagmus (apo-DCPN). Patients adopted FPP-one, which means lying down on the side of the weaker nystagmus during nightly rest for 2 weeks. ...
Source: Acta Oto-Laryngologica - October 31, 2009 Category: ENT & OMF Authors: Boleas-Aguirre MS, Pérez N, Batuecas-Caletrío A Tags: Acta Otolaryngol Source Type: journals

Poly(ADP-ribose) polymerase-1 (PARP-1) longer alleles spanning the promoter region may confer protection to bilateral Meniere's disease.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: The longer alleles (CA)17-20 of the promoter region of PARP-1 gene may confer some protection against bilateral Meniere's disease (BMD). OBJECTIVE: To analyze microsatellite (CA)(n) polymorphisms in the promoter region of PARP-1 gene and seek out risk and protective variants for BMD. SUBJECTS AND METHODS: Eighty patients from two ethnically defined groups with definite BMD, according to the diagnostic scale of the American Academy of Otolaryngology Head and Neck Surgery, were compared with a group of 371 normal controls from the same origin in a prospective multicenter study. We developed a specific amplificati...
Source: Acta Oto-Laryngologica - October 31, 2009 Category: ENT & OMF Authors: Lopez-Escamez JA, Moreno A, Bernal M, Perez-Garrigues H, Santos-Perez S, Soto-Varela A, Aran I, Fernandez-Sanfrancisco O, Lopez-Nevot A, Lopez-Nevot MA Tags: Acta Otolaryngol Source Type: journals

A head-tilt caloric test for evaluating the vertical semicircular canal function.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: The caloric test with head-tilt can be used as a tool for assessing vertical canal function as an office procedure. OBJECTIVE: Evaluation of vertical canal function. PATIENTS AND METHODS: We provoked caloric response by cold water in the vertiginous patients in supine position. During the culmination of the response we rotated the head 45 degrees from the sagittal plane to place the posterior canal to earth-vertical. Thereafter we rotated the head 45 degrees to the opposite direction to place the anterior canal to earth-vertical. The eye movements were recorded by two-dimensional electronystagmography. The dat...
Source: Acta Oto-Laryngologica - October 31, 2009 Category: ENT & OMF Authors: Aoki S, Arai Y, Yoda K, Nishida S Tags: Acta Otolaryngol Source Type: journals

Wine produced by ecological methods produces relatively little nasal blockage in wine-sensitive subjects.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: Subjects with self-reported nasal symptoms following consumption of red wine may respond with less nasal blockage to a wine produced with ecological methods than to wine not labelled as ecologically produced. OBJECTIVE: To compare nasal symptoms following intake of three different wines--one that was ecologically produced and two that were traditionally produced. SUBJECTS AND METHODS: Individuals with self-reported nasal symptoms following consumption of red wine were subjected to controlled intake of three different wines in a double-blinded, randomized, and crossover design. Nasal symptoms and peak nasal insp...
Source: Acta Oto-Laryngologica - October 31, 2009 Category: ENT & OMF Authors: Andersson M, Cervin-Hoberg C, Greiff L Tags: Acta Otolaryngol Source Type: journals

Value of nasal mucosa congestion index in choosing treatment strategies for chronic rhinosinusitis.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: The mucosa compliance in lesions is determined by the congestion index, enabling us to determine whether the patient is sensitive to pharmacotherapy and to choose surgical management rationally. OBJECTIVE: To explore the correlation between the nasal mucosa congestion index and tissue remodeling in chronic rhinosinusitis (CRS) and to provide objective evidence for clinical choice of therapeutic methods. PATIENTS AND METHODS: Forty-four patients with CRS who underwent nasal endoscopic surgery were enrolled in the study. The congestion indexes of the nasal mucosa were measured using an acoustic rhinometer and spe...
Source: Acta Oto-Laryngologica - October 31, 2009 Category: ENT & OMF Authors: Zang HR, Wang T, Li YC, Zhang SZ, Fan EZ, Han DM Tags: Acta Otolaryngol Source Type: journals

Expression of p53, p16INK4A, pRb, p21WAF1/CIP1, p27KIP1, cyclin D1, Ki-67 and HPV DNA in sinonasal endophytic Schneiderian (inverted) papilloma.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: Human papilloma virus (HPV) was associated with sinonasal inverted papilloma (SIP) in 14/20 (70%) patients with a prevalence of HPV 6/11; alterations of the cell cycle proteins were statistically significant. OBJECTIVES: We investigated SIPs relationships between HPV infection and aberrant expression of cell cycle proteins. MATERIALS AND METHODS: Twenty SIPs were evaluated for p53, p16(INK4a), pRb, p21(WAF1), p27(Kip1), cyclin D1 and Ki-67 expression by immunohistochemistry. HPV was investigated by polymerase chain reaction (PCR). RESULTS: HPV DNA was detected in 14/20 patients with inverted papillomas (IPs) (...
Source: Acta Oto-Laryngologica - October 31, 2009 Category: ENT & OMF Authors: Altavilla G, Staffieri A, Busatto G, Canesso A, Giacomelli L, Marioni G Tags: Acta Otolaryngol Source Type: journals

Effects of short inter-stimulus intervals on olfactory and trigeminal event-related potentials.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: Chemosensory event-related potentials (CSERPs) were identified in all measurements using the 20 s and the 10 s inter-stimulus interval (ISI) protocol, reducing the recording time to 75% or 57% compared with the standard protocol. A possible explanation for the rising CSERP amplitudes by shortening the ISI in CO(2) stimulation is due to a phenomenon known as trigeminal sensitization during repeated stimulation. OBJECTIVES: CSERPs are influenced by the ISI. The aim of this study was to evaluate the changes in CSERPs by decreasing the ISI from 30 s to 20 s or 10 s, respectively. SUBJECTS AND METHODS: Ten normosmic...
Source: Acta Oto-Laryngologica - October 31, 2009 Category: ENT & OMF Authors: Kassab A, Schaub F, Vent J, Hüttenbrink KB, Damm M Tags: Acta Otolaryngol Source Type: journals

Effects of topical drops and sprays on mucociliary transport time and nasal air flow.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: This study revealed that the nasal topical drops, which could be purchased without a proper prescription, should not be used randomly and non-selectively. OBJECTIVE: To investigate the effect of nasal drops and sprays on the nasal air flow and mucociliary transport time (MTT) in healthy volunteers with no septal deviation and no history of frequent upper respiratory infection. SUBJECTS AND METHods: Saline, fluticasone propionate drops and sprays, mometasone furoate, budesonide, xylometasoline chloride, fusafungine spray, Ringer's lactate and sea water were selected as the agents to be investigated. Volunteers w...
Source: Acta Oto-Laryngologica - October 31, 2009 Category: ENT & OMF Authors: Bercin S, Ural A, Kutluhan A Tags: Acta Otolaryngol Source Type: journals

Cytology of the nasal mucosa after total laryngectomy.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: This study demonstrates morphological changes in the nasal mucosa as a consequence of functional changes of the nasal cavity after total laryngectomy (TLE). OBJECTIVE: Observation of the changes of the nasal mucosa in patients after TLE. PATIENTS AND METHODS: A cohort observational study contained 30 patients after TLE. These patients underwent nasal endoscopy and cytological and microbiological examination of the nasal mucosa. The control group comprised 30 patients. RESULTS: In patients who underwent TLE, morphological changes occurred in the nasal mucosa. The hyperplasia of the cells in the basal zone was th...
Source: Acta Oto-Laryngologica - October 31, 2009 Category: ENT & OMF Authors: Skoloudik L, Vokurka J, Zborayova K, Celakovsky P, Kucera M, Ryska A Tags: Acta Otolaryngol Source Type: journals

Surgical intervention represents a feasible option for patients with mild obstructive sleep apnoea.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: Patients with mild obstructive sleep apnoea (OSA) depict the disease as being detrimental to their health, causing significant symptoms. These patients were found to achieve significant improvements in OSA-related symptoms after surgical intervention. OBJECTIVES: Although the effects of surgical treatment on OSA have been encouraging in many previous studies, little is known about its effects in patients with mild OSA. The aim of our study was to assess the evolution of symptoms experienced by mild OSA patients after surgical intervention. SUBJECTS AND METHODS: This was an observational follow-up study in a un...
Source: Acta Oto-Laryngologica - October 31, 2009 Category: ENT & OMF Authors: Sahlman J, Seppä J, Peltonen M, Pukkila M, Partinen M, Tuomilehto H Tags: Acta Otolaryngol Source Type: journals

Surgical management of retropharyngeal abscesses.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: Retropharyngeal abscess (RPA) is a rare, potentially life-threatening disease, requiring appropriate otorhinolaryngologic as well as radiologic diagnostics, and medical and surgical intervention by a transoral, transcervical or transnasal approach in a multidisciplinary setting. OBJECTIVES: The risks and benefits of surgical intervention in patients with RPA were assessed. The main outcome measure was the clinical resolution of the abscess. PATIENTS AND METHODS: A retrospective chart review was performed at a tertiary care university hospital over a period of 28 months. Eleven patients aged 1 to 68 years with t...
Source: Acta Oto-Laryngologica - October 31, 2009 Category: ENT & OMF Authors: Schuler PJ, Cohnen M, Greve J, Plettenberg C, Chereath J, Bas M, Koll C, Scheckenbach K, Wagenmann M, Schipper J, Hoffmann TK Tags: Acta Otolaryngol Source Type: journals

Uvulopalatopharyngoplasty in 158 OSAS patients failing non-surgical treatment.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: Uvulopalatopharyngoplasty (UPPP) in patients with obstructive sleep apnoea syndrome (OSAS) who had failed treatment with continuous positive airway pressure (CPAP) and mandibular retaining device (MRD) was effective and safe. The satisfaction rate was high. We recommend UPPP in selected OSAS patients, especially younger patients. OBJECTIVES: To evaluate the efficacy and complication rate of UPPP. PATIENTS AND METHODS: This was a non-randomized prospective study of 139 men and 19 women, median age 45 years (range 20-75), median body mass index (BMI) 29 (range 20-48), who underwent UPPP. One year follow-up compr...
Source: Acta Oto-Laryngologica - October 31, 2009 Category: ENT & OMF Authors: Lundkvist K, Januszkiewicz A, Friberg D Tags: Acta Otolaryngol Source Type: journals

Outcomes of type II thyroplasty for adductor spasmodic dysphonia: analysis of revision and unsatisfactory cases.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: The factors responsible for the observed failures can be broken into two major groups: (1) a wrong indication and (2) an inadequate technique to achieve relief from an excessively tight glottal closure. The use of a titanium bridge in place of a silicone shim was found to be essential. Type II thyroplasty can relieve the symptoms of adductor spasmodic dysphonia (AdSD) when implemented with a modern technique using titanium bridges. OBJECTIVES: To identify the factor or factors that necessitated revision surgery in type II thyroplasty for AdSD, detailed analytical examinations were made of individual cases with ...
Source: Acta Oto-Laryngologica - October 31, 2009 Category: ENT & OMF Authors: Sanuki T, Isshiki N Tags: Acta Otolaryngol Source Type: journals

Weekly paclitaxel for platin-resistant stage IV head and neck cancer patients.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: Weekly paclitaxel may be an active and well tolerated chemotherapy regimen for patients with platin-resistant advanced head and neck cancer. OBJECTIVES: Weekly paclitaxel should be an active and well tolerated regimen for palliative treatment of platin-resistant patients with recurrent or metastatic carcinoma of the head and neck. We analyzed the antitumor activity and toxicity profile. PATIENTS AND METHODS: Sixty consecutive patients with advanced head and neck cancer were treated with 1 h infusion of paclitaxel, 80 mg/m(2) weekly, for 6 consecutive weeks. Patients who showed disease response or disease stabi...
Source: Acta Oto-Laryngologica - October 31, 2009 Category: ENT & OMF Authors: Grau JJ, Caballero M, Verger E, Monzó M, Blanch JL Tags: Acta Otolaryngol Source Type: journals

Sleep apnoea in patients after treatment of head neck cancer.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: The prevalence of sleep apnoea among patients following treatment of head and neck carcinomas seems to be slightly higher than in the normal population. The possible importance of tumour treatment features, especially transient tracheostoma, needs further assessment. OBJECTIVES: The epidemiology of sleep apnoea in patients following the treatment of head and neck cancer remains unclear. This study was undertaken to assess the prevalence of sleep apnoea in head and neck cancer patients by characterizing their clinical, anatomical and tumour treatment features. PATIENTS AND METHODS: Our study examined 31 patient...
Source: Acta Oto-Laryngologica - October 31, 2009 Category: ENT & OMF Authors: Steffen A, Graefe H, Gehrking E, König IR, Wollenberg B Tags: Acta Otolaryngol Source Type: journals

Identification of epidermal growth factor receptor (EGFR) exon 20 single nucleotide polymorphism in Chinese squamous cell carcinoma of head and neck (SCCHN).Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: The 78th single nucleotide polymorphism (SNP) in exon 20 of epidermal growth factor receptor (EGFR) might be a predictor of the clinical course of squamous cell carcinoma of the head and neck (SCCHN), and genetic predisposition could influence the progression of SCCHN in Chinese subjects. OBJECTIVE: To analyze the clinical significance of EGFR SNP in Chinese SCCHN patients. MATERIALS AND METHODS: Direct sequencing of exons 18-21 was used to analyze somatic mutations of EGFR. Reverse transcriptase polymerase chain reaction (RT-PCR) was used to evaluate the expression level of EGFR. The chi-square test and Kaplan...
Source: Acta Oto-Laryngologica - October 31, 2009 Category: ENT & OMF Authors: Jin T, Yu CX, Jin T, Yu CX, Lei DP, Liu DY, Xu FL, Lu YT, Pan XL Tags: Acta Otolaryngol Source Type: journals