Interactive effects of age and hydration state on human thermoregulatory function during exercise in hot ‐dry conditions
ConclusionHypohydration attenuates heat loss via sweating in young but not middle ‐aged men, indicating that aging impairs one's ability to mitigate further sweat‐induced fluid loss during hypohydration.This article is protected by copyright. All rights reserved. (Source: Acta Physiologica)
Source: Acta Physiologica - November 27, 2018 Category: Physiology Authors: Robert D. Meade,
Sean R. Notley,
Andrew W. D'Souza,
Sheila Dervis,
Pierre Boulay,
Ronald J. Sigal,
Glen P. Kenny Tags: Regular Paper Source Type: research
Regulatory mechanisms of T cell activation – from basic research discoveries to a new principle of cancer therapy and the Nobel Prize
This article is protected by copyright. All rights reserved. (Source: Acta Physiologica)
Source: Acta Physiologica - November 24, 2018 Category: Physiology Authors: Juha P. V äyrynen,
Anne Tuomisto,
Markus J. Mäkinen Tags: Editorial Source Type: research
Circadian rhythms – daylight saving time, health, and body clocks
This article is protected by copyright. All rights reserved. (Source: Acta Physiologica)
Source: Acta Physiologica - November 23, 2018 Category: Physiology Authors: Karl ‐Heinz Herzig Tags: Editorial Source Type: research
Na+/Ca2+ Exchanger 1 is a Key Mechanosensitive Molecule of the Esophageal Myenteric Neurons
ConclusionsWe demonstrate a novel NCX1/Ca2+ pathway in the mechanosensitive neurons of rat and human esophagus, which may provide a potential therapeutic target for the treatment of esophageal motility disorders.This article is protected by copyright. All rights reserved. (Source: Acta Physiologica)
Source: Acta Physiologica - November 22, 2018 Category: Physiology Authors: Hui Dong,
Bo Tang,
Yanfen Jiang,
Ravinder K. Mittal Tags: Regular Paper Source Type: research
Role of melanocortin 4 receptor in hypertension induced by chronic intermittent hypoxia
ConclusionThese results show that obesity and the CNS melanocortin system interact in complex ways to elevate BP during CIH and that MC4R may be important in the ventilatory responses to hypercapnia.This article is protected by copyright. All rights reserved. (Source: Acta Physiologica)
Source: Acta Physiologica - November 22, 2018 Category: Physiology Authors: Jussara M. do Carmo,
Alexandre A. da Silva,
Sydney P. Moak,
Fernanda S. da Silva,
Frank T. Spradley,
John E. Hall Tags: Regular Paper Source Type: research
Circadian Rhythms
This article is protected by copyright. All rights reserved. (Source: Acta Physiologica)
Source: Acta Physiologica - November 20, 2018 Category: Physiology Authors: Pontus B. Persson,
Anja Bondke Persson Tags: Editorial Source Type: research
Mitochondrial complex IV mutation increases reactive oxygen species production and reduces lifespan in aged mice
ConclusionOur findings demonstrate that a complex IV mutation leads to mitochondrial dysfunction that translates into survival. (Source: Acta Physiologica)
Source: Acta Physiologica - November 20, 2018 Category: Physiology Authors: Gesine Reichart,
Johannes Mayer,
Cindy Zehm,
Timo Kirschstein,
Tursonjan Tokay,
Falko Lange,
Simone Baltrusch,
Markus Tiedge,
Georg Fuellen,
Saleh Ibrahim,
R üdiger Köhling Tags: ORIGINAL ARTICLE Source Type: research
Cachexia does not induce loss of myonuclei or muscle fibres during xenografted prostate cancer in mice
ConclusionThe data suggest that the cachexia induced by xenografted prostate tumours induces a pronounced atrophy not accompanied by a loss of myonuclei or a loss of muscle fibres. Thus, stem cell related treatment might be redundant, and the quest for treatment options should rather focus on intervening with intracellular pathways regulating muscle fibre size. (Source: Acta Physiologica)
Source: Acta Physiologica - November 16, 2018 Category: Physiology Authors: Ivan Myhre Winje,
Xia Sheng,
Kenth ‐Arne Hansson,
Andreas Solbrå,
Simen Tennøe,
Fahri Saatcioglu,
Jo Christiansen Bruusgaard,
Kristian Gundersen Tags: REGULAR PAPER Source Type: research
Issue Information
Acta Physiologica, Volume 224, Issue 4, December 2018. (Source: Acta Physiologica)
Source: Acta Physiologica - November 15, 2018 Category: Physiology Tags: ISSUE INFORMATION Source Type: research
Mitophagy as a new therapeutic target for sarcopenia
This article is protected by copyright. All rights reserved. (Source: Acta Physiologica)
Source: Acta Physiologica - November 15, 2018 Category: Physiology Authors: Andrea del Campo Tags: Editorial Source Type: research
Another record in submissions to Acta Physiologica
This article is protected by copyright. All rights reserved. (Source: Acta Physiologica)
Source: Acta Physiologica - November 12, 2018 Category: Physiology Authors: P. B. Persson Tags: Editorial Source Type: research
Energy efficient physiologic coupling of gait and respiration is altered in chronic obstructive pulmonary disease
ConclusionThe novel finding was that increased energy expenditure was associated with stronger and less complex coupling. Increased effort is needed when utilizing a frequency ratio of 1:1 or 3:2. The more stable the coupling, the more effort it takes to walk. In contrast to the complex energy efficient coupling of controls, those with airflow obstruction manifested simpler and stronger coupling associated with reduced energy efficiency.This article is protected by copyright. All rights reserved. (Source: Acta Physiologica)
Source: Acta Physiologica - November 10, 2018 Category: Physiology Authors: Jennifer M. Yentes,
William Denton,
Kaeli Samson,
Kendra K. Schmid,
Casey Wiens,
Stephen I. Rennard Tags: Regular Paper Source Type: research
Exercise Training Remodels Human Skeletal Muscle Mitochondrial Fission and Fusion Machinery Towards a Pro ‐Elongation Phenotype
ConclusionsExercise training alters the expression of mitochondrial fusion and fission proteins, promoting a more fused, tubular network. These changes may contribute to the improvements in insulin sensitivity and substrate utilization that are observed after exercise training.This article is protected by copyright. All rights reserved. (Source: Acta Physiologica)
Source: Acta Physiologica - November 8, 2018 Category: Physiology Authors: Christopher L. Axelrod,
Ciar án E. Fealy,
Anny Mulya,
John P. Kirwan Tags: Regular Paper Source Type: research
Critical illness myopathy: Glucocorticoids revisited?
Acta Physiologica, EarlyView. (Source: Acta Physiologica)
Source: Acta Physiologica - November 3, 2018 Category: Physiology Authors: Werner J. Z ’Graggen,
Joerg C. Schefold Source Type: research
Epac1 −/− mice have elevated baseline permeability and do not respond to histamine as measured with dynamic contrast‐enhanced magnetic resonance imaging with contrast agents of different molecular weights
Acta Physiologica, EarlyView. (Source: Acta Physiologica)
Source: Acta Physiologica - November 3, 2018 Category: Physiology Authors: Fitz ‐Roy E. Curry,
Torfinn Taxt,
Cecilie Brekke Rygh,
Tina Pavlin,
Ronja Bjønrstad,
Stein Ove Døskeland,
Rolf K. Reed Source Type: research
