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[Human metapneumovirus (HMPV) infections in young children]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Human metapneumovirus (hMPV) is a recently discovered respiratory virus. hMPV, the second after respiratory syncytial virus (RSV), is leading cause of upper and lower respiratory tract infections mainly in infants and children. hMPV infections have been reported in many countries in all the world, in patients in every age and gender, but children under 5 years are most likely to be susceptible to infections caused by hMPV. The frequency of hMPV infections require hospitalization in this group is 5-10%. Late winter and early spring is the epidemic peak of hMPV infections in a lot of countries. The similar time of hMPV i...
Source: Adv Data - November 12, 2009 Category: Epidemiology Authors: Panasik A, Pancer K Tags: Przegl Epidemiol Source Type: journals

Experiment results of time-reversal communication in the deep ocean at the range of 300 km.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The research is being conducted to realize communication with a long cruising AUV in the deep ocean using time reversal. We have proposed the method of combining time reversal and adaptive equalization. In our previous at-sea experiments, the performance of time-reversal communication was confirmed at the range of 10-100 km with a virtual array. In our latest sea-trial, experiments of passive time-reversal communication were executed at the range of 300 km with a real receiver array. As a probe signal, chirp pulses and M-sequence pulses were used. The data transmission speed was 50 and 100 bps. The source was suspended...
Source: Adv Data - September 30, 2009 Category: Epidemiology Authors: Shimura T, Ochi H, Watanabe Y, Hattori T Tags: J Acoust Soc Am Source Type: journals

Excretion of the novel polyomaviruses KI and WU in the stool of patients with hematological disorders.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In this study, stool specimens from 31 patients with hematological disorders (25 transplanted and 6 non-transplanted) were examined prospectively to determine whether the novel polyomaviruses KIV and WUV reactivated and were excreted in the gastrointestinal tract. Reactivation was correlated with the appearance of gastrointestinal and respiratory symptoms. Of the 31 patients examined, KIV and WUV were detected in 13 transplanted patients as single infection or in combination with BKV, cytomegalovirus (CMV), and adenovirus (Adv). Because of frequent co-infections, a clear correlation between novel polyomaviruses and clinica...
Source: Adv Data - August 31, 2009 Category: Epidemiology Authors: Babakir-Mina M, Ciccozzi M, Alteri C, Polchi P, Picardi A, Greco F, Lucarelli G, Arcese W, Perno CF, Ciotti M Tags: J Med Virol Source Type: journals

Simultaneous detection of human bocavirus and adenovirus by multiplex real-time PCR in a Belgian paediatric population.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Since the discovery of human bocavirus (hBoV), the virus has been detected worldwide in respiratory tract samples from young children by various polymerase chain reaction (PCR) assays and real-time PCRs (Q-PCR). Until now, no data have been reported on the presence of hBoV in Belgium and the detection of hBoV in a multiplex Q-PCR setting has not been described. The aim of this study was to develop a fast and reliable multiplex Q-PCR for the simultaneous detection of hBoV DNA and adenovirus (AdV) DNA. During the winter of 2004-2005, 445 nasopharyngeal aspirates (NPAs) were analysed from 404 Belgian children up to 5 year...
Source: Adv Data - August 24, 2009 Category: Epidemiology Authors: De Vos N, Vankeerberghen A, Vaeyens F, Van Vaerenbergh K, Boel A, De Beenhouwer H Tags: Eur J Clin Microbiol Infect Dis Source Type: journals

Detection of human papillomavirus and adenovirus in benign and malignant lesions of the larynx.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: The absence of viral genomes in laryngeal carcinomas as in the other cases studied suggests the existence of other factors that play a more important role than viral infection in the carcinogenesis of these lesions. PMID: 19643265 [PubMed - as supplied by publisher] (Source: Adv Data)
Source: Adv Data - July 31, 2009 Category: Epidemiology Authors: Gallo A, Degener AM, Pagliuca G, Pierangeli A, Bizzoni F, Greco A, de Vincentiis M Tags: Otolaryngol Head Neck Surg Source Type: journals

Adefovir dipivoxil and pegylated interferon alpha for the treatment of chronic hepatitis B: an updated systematic review and economic evaluation.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: Both ADV and PEG-alpha are beneficial for patients with CHB in terms of suppressing viral load, reducing liver damage-associated biochemical activity, inducing HBeAg seroconversion, and reducing liver fibrosis and necroinflammation. The effects of long-term treatment with ADV are generally durable, with relatively low rates of resistance. In most cases, cost-effectiveness estimates were within acceptable ranges. Further research should assess the clinical effectiveness and cost-effectiveness of newer antiviral agents in relation to existing drugs, including the role of initiating treatment with combination the...
Source: Adv Data - June 30, 2009 Category: Epidemiology Authors: Jones J, Shepherd J, Baxter L, Gospodarevskaya E, Hartwell D, Harris P, Price A Tags: Health Technol Assess Source Type: journals

Transduction of adenovirus vectors modified with cell-penetrating peptides.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Adenovirus vectors (Advs) are widely used for basic and clinical research because of their high transduction efficiency. However, they are poorly transduced into cells lacking the primary adenovirus receptor, the coxsackievirus and adenovirus receptor (CAR). Here, we generated Adv conjugated with cell-penetrating peptides (CPPs), such as Tat, octaarginine (R8) or proline-rich (Pro) peptides, and compared the transduction properties of these constructs. We constructed the Advs conjugated to the CPPs (CPP-Adv) by chemical conjugation. The CPP-conjugated Advs created with optimal modification ratios led to gene expression...
Source: Adv Data - May 22, 2009 Category: Epidemiology Authors: Eto Y, Yoshioka Y, Asavatanabodee R, Kida S, Maeda M, Mukai Y, Mizuguchi H, Kawasaki K, Okada N, Nakagawa S Tags: Peptides Source Type: journals

Renal dysfunction in chronic hepatitis B patients treated with adefovir dipivoxil.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: ADV is an independent predictor for significant deterioration of renal function. Patients on ADV should be monitored, especially patients who are older, have baseline renal insufficiency, or have hypertension and/or diabetes mellitus. (HEPATOLOGY 2009.). PMID: 19517525 [PubMed - as supplied by publisher] (Source: Adv Data)
Source: Adv Data - April 23, 2009 Category: Epidemiology Authors: Ha NB, Ha NB, Garcia RT, Trinh HN, Vu AA, Nguyen HA, Nguyen KK, Levitt BS, Nguyen MH Tags: Hepatology Source Type: journals

An experimental and theoretical investigation of flow in a gross pollutant trap.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Flow through a gross pollutant trap (GPT) with fully blocked screens is investigated experimentally and theoretically using computational fluid dynamics (CFD). Due to the wide range of possible flow regimes, an experimental approach is developed which uses a downstream weir arrangement to control the nature of the flow and the variation in free surface height. To determine the overall flow structure, measurements are taken at a fixed depth throughout the trap with an Acoustic Doppler Velocimeter (ADV), including velocity profile data across three cross sections of the GPT suitable for more detailed comparison with simu...
Source: Adv Data - April 11, 2009 Category: Epidemiology Authors: Madhani JT, Kelson NA, Brown RJ Tags: Water Sci Technol Source Type: journals

Involvement of asymmetric dimethylarginine (ADMA) in glomerular capillary loss and sclerosis in a rat model of chronic kidney disease (CKD).Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In this study, we investigated whether lowering of ADMA by overexpression of dimethylarginine dimethylaminohydrolase (DDAH), a main enzyme that degrades ADMA, could ameliorate glomerular capillary loss and sclerosis in a rat model of CKD. Four weeks after 5/6 subtotal nephrectomy (Nx), animals were given tail vein injections with recombinant adenovirus vector encoding DDAH-I (Adv-DDAH) or control vector expressing bacterial b-galactosidase (Adv-LZ), or orally administered with 20mg/kg/day of hydralazine (Hyz) which served as a blood pressure control model. KEY FINDINGS: Plasma levels of ADMA were associated with decreased ...
Source: Adv Data - April 4, 2009 Category: Epidemiology Authors: Ueda S, Yamagishi SI, Matsumoto Y, Kaida Y, Fujimi-Hayashida A, Koike K, Tanaka H, Fukami K, Okuda S Tags: Life Sci Source Type: journals

Long-Term Cardiac-Targeted RNA Interference for the Treatment of Heart Failure Restores Cardiac Function and Reduces Pathological Hypertrophy.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions-Our data show for the first time the high efficacy of an RNAi therapeutic strategy in a cardiac disease. PMID: 19237664 [PubMed - as supplied by publisher] (Source: Adv Data)
Source: Adv Data - February 23, 2009 Category: Epidemiology Authors: Suckau L, Fechner H, Chemaly E, Krohn S, Hadri L, Kockskämper J, Westermann D, Bisping E, Ly H, Wang X, Kawase Y, Chen J, Liang L, Sipo I, Vetter R, Weger S, Kurreck J, Erdmann V, Tschope C, Pieske B, Lebeche D, Schultheiss HP, Hajjar RJ, Poller WC Tags: Circulation Source Type: journals

A short course of add-on adefovir dipivoxil treatment in lamivudine-resistant chronic hepatitis B patients.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Summary. The aims of the study were to investigate the efficacy of rescue therapy with lamivudine (LAM) and adefovir (ADV) combination for 6 months followed by ADV monotherapy in lamivudine-resistant chronic hepatitis B (LAM-R CHB) patients, and to analyze the frequency of ADV resistance mutant development in such patients. A total of 170 consecutive LAM-R CHB patients (male/female: 130/40, mean age: 42.9 +/- 13.4 years) with viral breakthrough under LAM therapy were analyzed. A total of 68 had HBeAg-positive. Patients received rescue therapy with LAM [100 mg (qd)]+ADV [10 mg (qd)] for 6 months after which LAM was disc...
Source: Adv Data - February 12, 2009 Category: Epidemiology Authors: Idilman R, Kaymakoglu S, Oguz Onder F, Ahishali E, Bektas M, Cinar K, Pınarbasi B, Karayalcin S, Badur S, Cakaloglu Y, Mithat Bozdayi A, Bozkaya H, Okten A, Yurdaydin C Tags: J Viral Hepat Source Type: journals

293 cell cycle synchronisation adenovirus vector production.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
As the market requirements for adenovirus vectors (AdV) increase, the maximisation of the virus titer per culture volume per unit time is a key requirement. However, despite the fact that 293 cells can grow up to 8 x 10(6) cell/mL in simple batch mode operations, for optimal AdV infection a maximum cell density of 1 x 10(6) cell/mL at infection time has usually been utilized due to the so called "cell density effect". In addition, AdV titer appears to be dependent upon cell cycle phase at the time of infection. To evaluate the dependence of AdV production upon cell cycle phase, 293 cells were chemically synchronised at...
Source: Adv Data - January 9, 2009 Category: Epidemiology Authors: Ferreira TB, Perdigão R, Silva AC, Zhang C, Aunins JG, Carrondo MJ, Alves PM Tags: Biotechnol Prog Source Type: journals

'Visible-ness': the nature of communication for children admitted to a specialist children's hospital in the Republic of Ireland.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion. This study provides empirical insight into children's experiences of communication in an inpatient hospital setting. A key recommendation calls for the development of communication assessment strategies to determine the 'ideal' position children would like to occupy, at any given point in time, along the 'visible-ness' continuum. Relevance to practice. This study emphasises the need for all health professionals to embrace the individualism of each child patient with regard to their specific communication needs. PMID: 19012779 [PubMed - as supplied by publisher] (Source: Adv Data)
Source: Adv Data - November 19, 2008 Category: Epidemiology Authors: Lambert V, Glacken M, McCarron M Tags: J Clin Nurs Source Type: journals

Dealing with chaos and complexity: the reality of interviewing children and families in their own homes.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions. Dealing with perceived chaos is hard in reality, but capturing it is part of the complexity of qualitative enquiry. The context is interdependent with children's perceived reality, because they communicate with others through their environment. Relevance to practice. This paper gives researchers an insight into the tensions of operating out in the field and helps raise the importance of the environmental 'chaos' in revealing significant issues relevant to peoples daily lives. Knowing that unexpected chaos is part and parcel of qualitative research, will equip researchers with skills fundamental for balancing t...
Source: Adv Data - November 19, 2008 Category: Epidemiology Authors: Macdonald K, Greggans A Tags: J Clin Nurs Source Type: journals

Correlation between changes in CSF dopamine turnover and development of dyskinesia in Parkinson's disease.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
To assess possible differences in dopamine metabolism that could parallel disease progression in Parkinson's disease (PD), we measured dopamine (DA) and its metabolites in the cerebrospinal fluid (CSF) in PD patients at different stages of disease: de novo (DEN), advanced not showing dyskinesias (ADV), and advanced with dyskinesias (DYS). DA, homovanillic acid (HVA) and dihydroxyphenylacetic acid (DOPAC) were significantly higher in DEN patients compared with other groups. A negative exponential correlation related DA level and disease duration. The HVA/DA ratio was significantly higher in the ADV and DYS group than th...
Source: Adv Data - November 14, 2008 Category: Epidemiology Authors: Lunardi G, Galati S, Tropepi D, Moschella V, Brusa L, Pierantozzi M, Stefani A, Rossi S, Fornai F, Fedele E, Stanzione P, Hainsworth AH, Pisani A Tags: Parkinsonism Relat Disord Source Type: journals

Tat conjugation of adenovirus vector broadens tropism and enhances transduction efficiency.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In this study, we attempted to generate novel Tat-Advs (Advs conjugated with the HIV Tat-derived peptide, a protein-transduction domain (PTD)) to broaden Adv tropism and enhance transduction efficiency. MAIN METHODS: We constructed Tat-Advs by chemically conjugating Tat peptide to the surface-exposed lysine residues on Advs. We compared the gene transfer activity of Tat-Advs with that of unmodified Advs by measuring the luciferase expression in several types of cell lines. KEY FINDINGS: Tat-Advs showed gene expression 1 to 3 log orders higher than unmodified Advs in CAR-negative adherent cells and blood cells, which are re...
Source: Adv Data - October 5, 2008 Category: Epidemiology Authors: Yoshioka Y, Asavatanabodee R, Eto Y, Watanabe H, Morishige T, Yao X, Kida S, Maeda M, Mukai Y, Mizuguchi H, Kawasaki K, Okada N, Nakagawa S Tags: Life Sci Source Type: journals

Hepatitis B and liver transplantation: 2008 update.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The ultimate goal of treatment is suppression of viral replication to undetectable HBV-DNA levels prior to and after liver transplantation (LT) to prevent infection of the newly transplanted liver. Most published data are available from therapy with lamivudine (LAM) in pre- and post-transplant HBV patients. Add-on therapy with adefovir dipivoxil (ADV) in pre-transplant LAM-resistant patients has been shown to represent an effective antiviral strategy leading to hepatic recompensation in many cases and, eventually, removal from the waiting list. Newer nucleos(t)ide analogues such as entecavir, tenofovir and telbivudine ...
Source: Adv Data - September 24, 2008 Category: Epidemiology Authors: Beckebaum S, Sotiropoulos GC, Gerken G, Cicinnati VR Tags: Rev Med Virol Source Type: journals

Adefovir dipivoxil is effective for the treatment of cirrhotic patients with lamivudine failure.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: Adefovir dipivoxil provides effective and safe treatment in cirrhotic and elderly patients who failed LAM therapy. PMID: 18795900 [PubMed - as supplied by publisher] (Source: Adv Data)
Source: Adv Data - September 15, 2008 Category: Epidemiology Authors: Zoulim F, Parvaz P, Marcellin P, Zarski JP, Beaugrand M, Benhamou Y, Bailly F, Maynard M, Trepo C, Trylesinski A, Monchecourt F, Tags: Liver Int Source Type: journals

Three-dimensional reconstruction of human CFTR chloride channel revealed an ellipsoidal structure with orifices beneath the putative transmembrane domain.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The cystic fibrosis transmembrane regulator (CFTR) chloride channel is a membrane integral protein that belongs to an ATP-binding cassette superfamily. Mutations in the CFTR gene cause cystic fibrosis (CF) in which salt, water and protein transports are defective in various tissues. Here we have expressed wild-type human CFTR as a FLAG-fused protein in HEK293 cells heterologously, and purified it in three steps: anti-FLAG and wheat germ agglutinin affinity chromatographies and size exclusion chromatography. The stoichiometry of the protein was analyzed using various biochemical approaches, including chemical cross-link...
Source: Adv Data - August 22, 2008 Category: Epidemiology Authors: Mio K, Ogura T, Mio M, Shimizu H, Hwang TC, Sato C, Sohma Y Tags: J Biol Chem Source Type: journals

Cryoelectron microscopy map of Atadenovirus reveals cross-genus structural differences from human adenovirus.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A three-dimensional (3D) cryoelectron microscopy reconstruction of the prototype Atadenovirus (OAdV [an ovine adenovirus isolate]) showing information at a 10.6-A resolution (0.5 Fourier shell correlation) was derived by single-particle analysis. This is the first 3D structure solved for any adenovirus that is not a Mastadenovirus, allowing cross-genus comparisons between structures and the assignment of genus-specific capsid proteins. Viable OAdV mutants that lacked the genus-specific LH3 and p32k proteins in purified virions were also generated. Negatively stained 3D reconstructions of these mutants were used to iden...
Source: Adv Data - August 1, 2008 Category: Epidemiology Authors: Pantelic RS, Lockett LJ, Rothnagel R, Hankamer B, Both GW Tags: J Virol Source Type: journals

Novel polymer carriers and gene constructs for treatment of myocardial ischemia and infarction.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The number one cause of mortality in the US is cardiovascular related disease. Future predictions do not see a reduction in this rate especially with the continued rise in obesity [P. Poirier, et al., Obesity and cardiovascular disease: pathophysiology, evaluation, and effect of weight loss, Arterioscler Thromb Vasc Biol. 26(5), (2006) 968-976.; K. Obunai, S. Jani, G.D. Dangas, Cardiovascular morbidity and mortality of the metabolic syndrome, Med.Clin. North Am., 91(6), (2007) 1169-1184.]. Even so, potential molecular therapeutic targets for cardiac gene delivery are in no short supply thanks to continuing advances in ...
Source: Adv Data - July 6, 2008 Category: Epidemiology Authors: Yockman JW, Kastenmeier A, Erickson HM, Brumbach JG, Whitten MG, Albanil A, Li DY, Kim SW, Bull DA Tags: J Control Release Source Type: journals

[Comparison of antiviral responses to adefovir dipivoxil therapy of genotype B and genotype C HBV infected patients.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: Our results suggest that genotype B HBV has a better virological response to ADV therapy in HBeAg-positive chronic hepatitis B patients than that of genotype C. Longer terms of ADV treatment are needed to confirm this conclusion. [Chinese FullText URL http://zhgz.chinajournal.net.cn]. PMID: 18578989 [PubMed - in process] (Source: Adv Data)
Source: Adv Data - June 1, 2008 Category: Epidemiology Authors: Zeng AZ, Deng H, Peng FY, Xin XJ, Yang C, Li QL, Guo JJ, Zhang ZZ, Hao MJ, Yuan Z, Huang WX, Huang AL Tags: Zhonghua Gan Zang Bing Za Zhi Source Type: journals

Regulation of antigen presentation machinery in human dendritic cells by recombinant adenovirus.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Recombinant adenoviral vectors (AdV) are potent vehicles for antigen engineering of dendritic cells (DC). DC engineered with AdV to express full length tumor antigens are capable stimulators of antigen-specific polyclonal CD8+ and CD4+ T cells. To determine the impact of AdV on the HLA class I antigen presentation pathway, we investigated the effects of AdV transduction on antigen processing machinery (APM) components in human DC. Interactions among AdV transduction, maturation, APM regulation and T cell activation were investigated. The phenotype and cytokine profile of DC transduced with AdV was intermediate, between...
Source: Adv Data - May 17, 2008 Category: Epidemiology Authors: Vujanovic L, Whiteside TL, Potter DM, Chu J, Ferrone S, Butterfield LH Tags: Cancer Immunol Immunother Source Type: journals

Stochastic models for phylogenetic trees on higher-order taxa.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We present a general framework for such models, and describe three alternate classification schemes. Combining with the species-level model of Aldous and Popovic (Adv Appl Probab 37:1094-1115, 2005), one gets models for higher-order trees, and we initiate analytic study of such models. In particular we derive formulas for the lifetime of genera, for the distribution of number of species per genus, and for the offspring structure of the tree on genera. PMID: 17909814 [PubMed - indexed for MEDLINE] (Source: Adv Data)
Source: Adv Data - April 1, 2008 Category: Epidemiology Authors: Aldous D, Krikun M, Popovic L Tags: J Math Biol Source Type: journals

Comparison between Sendai virus and adenovirus vectors to transduce HIV-1 genes into human dendritic cells.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In this study, we compared the efficiency of inducing green fluorescent protein (GFP) and HIV-1 gene expression in human monocyte-derived DCs between SeV and adenovirus (AdV). Human monocyte-derived DCs infected with SeV showed the maximum gene expression 24 hr after infection at a multiplicity of infection (MOI) of 2. Although SeV vector showed higher cytopathic effect on DCs than AdV, SeV vector induced maximum gene expression earlier and at much lower MOI. In terms of cell surface phenotype, both SeV and AdV vectors induced DC maturation. DCs infected with SeV as well as AdV elicited HIV-1 specific T-cell responses dete...
Source: Adv Data - March 1, 2008 Category: Epidemiology Authors: Hosoya N, Miura T, Kawana-Tachikawa A, Koibuchi T, Shioda T, Odawara T, Nakamura T, Kitamura Y, Kano M, Kato A, Hasegawa M, Nagai Y, Iwamoto A Tags: J Med Virol Source Type: journals

[Surgery training of gynecologic residents: master and student in the operating room]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: Decision to let the resident operate remains too dependent on senior personal appreciation and does not seem to join a strategy of training. Opinions of surgical training in the operating room is different between residents and seniors. Operating time increases when residents operate but there is no effect on quality of care. These results show again the necessity of a formal teaching and assessment, in a resident program with objectives, collecting every resident's surgery volume. These educational improvements will contribute certainly to the professionalization of residents. PMID: 18243030 [PubMed - inde...
Source: Adv Data - February 1, 2008 Category: Epidemiology Authors: Rathat G, Hoa D, Gagnayre R, Hoffet M, Mares P Tags: Gynecol Obstet Fertil Source Type: journals

Health characteristics of the Asian adult population: United States, 2004-2006.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This report compares national estimates for selected health status indicators, health behaviors, health care utilization, health conditions, immunizations, and human immunodeficiency virus (HIV) testing status among selected non-Hispanic Asian adult subgroups. Comparison estimates for the non-Hispanic white, non-Hispanic black, non-Hispanic American Indian or Alaska Native (AIAN), and Hispanic adult populations are also presented. METHODS: The estimates in this report were derived from the Family Core and the Sample Adult Core components of the 2004-2006 National Health Interview Surveys (NHIS), conducted by the Centers fo...
Source: Adv Data - January 22, 2008 Category: Epidemiology Authors: Barnes PM, Adams PF, Powell-Griner E Tags: Adv Data Source Type: journals

Electronic medical record use by office-based physicians and their practices: United States, 2006.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This report presents the latest information on the use of electronic medical records in physician offices. Percentages of medical practices and physicians within the practices using electronic medical records (EMR) are presented for 2006 by selected physician and practice characteristics. METHODS: Data from the physician induction interviews of the 2006 National Ambulatory Medical Care Survey (NAMCS) are presented. NAMCS includes a national probability sample of nonfederal office-based physicians who saw patients in an office setting. Sample data were weighted to produce national estimates of physicians. Estimates of medic...
Source: Adv Data - October 26, 2007 Category: Epidemiology Authors: Hing ES, Burt CW, Woodwell DA Tags: Adv Data Source Type: journals

Fall injury episodes among noninstitutionalized older adults: United States, 2001-2003.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: Fall injuries remain very prevalent among older adults and result in high health care utilization and activity limitations. Rates of fall injuries vary by demographic and health characteristics of older noninstitutionalized adults. PMID: 17953135 [PubMed - in process] (Source: Adv Data)
Source: Adv Data - September 21, 2007 Category: Epidemiology Authors: Schiller JS, Kramarow EA, Dey AN Tags: Adv Data Source Type: journals

Emergency response planning in hospitals, United States: 2003-2004.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This study presents baseline data to determine which hospital characteristics are associated with preparedness for terrorism and natural disaster in the areas of emergency response planning and availability of equipment and specialized care units. METHODS: Information from the Bioterrorism and Mass Casualty Preparedness Supplements to the 2003 and 2004 National Hospital Ambulatory Medical Care Surveys was used to provide national estimates of variations in hospital emergency response plans and resources by residency and medical school affiliation, hospital size, ownership, metropolitan statistical area status, and Joint Co...
Source: Adv Data - August 20, 2007 Category: Epidemiology Authors: Niska RW, Burt CW Tags: Adv Data Source Type: journals

National Ambulatory Medical Care Survey: terrorism preparedness among office-based physicians, United States, 2003-2004.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
OBJECTIVES: This investigation describes terrorism preparedness among U.S. office-based physicians and their staffs in identification and diagnosis of terrorism-related conditions, training methods and sources, and assistance with diagnosis and reporting. METHODS: The National Ambulatory Medical Care Survey (NAMCS) is an annual national probability survey of approximately 3,000 U.S. nonfederal, office-based physicians. Terrorism preparedness items were added in 2003 and 2004. RESULTS: About 40 percent of physicians or their staffs received training for anthrax or smallpox, but less than one-third received training for ...
Source: Adv Data - July 24, 2007 Category: Epidemiology Authors: Niska RW, Burt CW Tags: Adv Data Source Type: journals

2005 National Hospital Discharge Survey.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This report presents national estimates of the use of nonfederal short-stay hospitals in the United States during 2005 and selected trend data. Numbers and rates of discharges, diagnoses, and procedures are shown by age and sex. Average lengths of stay are presented for all discharges and for selected diagnostic categories by age and by sex. METHODS: The estimates are based on data collected through the 2005 National Hospital Discharge Survey (NHDS). The survey has been conducted annually by NCHS since 1965. Diagnoses and procedures presented are coded using the International Classification of Diseases, Ninth Revision, Cli...
Source: Adv Data - July 12, 2007 Category: Epidemiology Authors: DeFrances CJ, Hall MJ Tags: Adv Data Source Type: journals

Drug use and sexual behaviors reported by adults: United States, 1999-2002.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This report presents prevalence estimates for self-reported adult drug use and sexual behaviors in the United States. Data are from the National Health and Nutrition Examination Survey (NHANES) collected from 1999 to 2002. NHANES surveys a stratified multistage probability sample of the civilian noninstitutionalized population of the United States. Tables included in this report present estimates for use of cocaine, including crack or freebase, or other street drugs, and sexual behavior by selected sociodemographic characteristics among adults 20-59 years of age. PMID: 17668724 [PubMed - in process] (Source: Adv Data)
Source: Adv Data - June 28, 2007 Category: Epidemiology Authors: Fryar CD, Hirsch R, Porter KS, Kottiri B, Brody DJ, Louis T Tags: Adv Data Source Type: journals

Characteristics of adults with serious psychological distress as measured by the K6 scale: United States, 2001-04.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS:The associations between SPD and sociodemographic characteristics, health status, and health care utilization are similar to the relationships found between serious mental illnesses (for example, major depression or schizophrenia) and these same variables. Persons with SPD demonstrate disadvantage in both socioeconomic status and health outcomes. PMID: 17432488 [PubMed - in process] (Source: Adv Data)
Source: Adv Data - March 30, 2007 Category: Epidemiology Authors: Pratt LA, Dey AN, Cohen AJ Tags: Adv Data Source Type: journals

Office-based medical practices: methods and estimates from the national ambulatory medical care survey.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
OBJECTIVES: The report uses a multiplicity estimator from a sample of office-based physicians to estimate the number and characteristics of medical practices in the United States. Practice estimates are presented by characteristics of the practice (solo or group, single, or multi-specialty group, size of practice, ownership, location, number of managed care contracts, use of electronic medical records, and use of computerized physician order entry systems). METHODS: Data presented in this report were collected during physician induction interviews for the 2003-04 National Ambulatory Medical Care Survey (NAMCS). The NAM...
Source: Adv Data - March 12, 2007 Category: Epidemiology Authors: Hing E, Burt CW Tags: Adv Data Source Type: journals

The state of childhood asthma, United States, 1980-2005.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Authors: Akinbami L, PMID: 17180851 [PubMed - in process] (Source: Adv Data)
Source: Adv Data - December 22, 2006 Category: Epidemiology Source Type: journals

Total, free, and percent free prostate-specific antigen levels among U.S. men, 2001-04.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: The effect of lowering the total PSA thresholds increases the number of U.S. men who would be referred for screening for prostate cancer. Total and free PSA increased with age in Mexican American, non-Hispanic white, and non-Hispanic black men. Information about the distribution of total, free, and percent free PSA will help guide public health policy in screening for prostate cancer. PMID: 17348177 [PubMed - in process] (Source: Adv Data)
Source: Adv Data - December 4, 2006 Category: Epidemiology Authors: Lacher DA, Thompson TD, Hughes JP, Saraiya M Tags: Adv Data Source Type: journals

Measuring HIV risk in the U.S. population aged 15-44: results from Cycle 6 of the National Survey of Family Growth.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This report presents national estimates of the percentage and number of persons in the U.S. population aged 15-44 who report behaviors that place them at increased risk for acquiring or transmitting human immunodeficiency virus, or HIV. The report also contains data on condom use and HIV testing by persons who report risk behaviors. In addition, estimates of self-reported risk for HIV from the Cycle 6 National Survey of Family Growth (NSFG) are compared with data from other recent national surveys. METHODS: Data from the NSFG Cycle 6, conducted by the Centers for Disease Control and Prevention's (CDC) National Center for H...
Source: Adv Data - November 12, 2006 Category: Epidemiology Source Type: journals

Staffing, capacity, and ambulance diversion in emergency departments: United States, 2003-04.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This report presents estimates of structure and process characteristics of hospital EDs related to their capacity to treat medical and surgical emergencies. Estimates of EDs experiencing crowded conditions are also presented. METHODS: Several facility supplements were added to the 2003-04 National Hospital Ambulatory Medical Care Survey (NHAMCS), which were completed by hospital staff. NHAMCS samples nonfederal, short-stay, and general hospitals in the United States. Of all sample hospitals that operated 24-hour EDs, 83 percent completed the supplemental questionnaires. Data from 467 hospitals were weighted to produce nati...
Source: Adv Data - October 15, 2006 Category: Epidemiology Source Type: journals

Prevalence of functional limitations among adults 60 years of age and over: United States, 1999-2002.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This report contains prevalence estimates and standard errors for adults, 60 years of age and over, who reported difficulty performing these activities without the aid of special equipment or who were not able to perform these activities. Results are reported by sex, age group, race and ethnicity, and body mass index (BMI). Assessment of functional status plays an important role in monitoring the health problems and needs of older Americans. PMID: 16964780 [PubMed - in process] (Source: Adv Data)
Source: Adv Data - August 23, 2006 Category: Epidemiology Authors: Ervin RB Source Type: journals

National Ambulatory Medical Care Survey: 2004 summary.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This report describes ambulatory care visits made to physician offices in the United States. Statistics are presented on selected characteristics of the physician's practice, the patient, and the visit. Selected trends in office visits are also presented. METHODS: The data presented in this report were collected in the 2004 National Ambulatory Medical Care Survey (NAMCS), a national probability sample survey of visits to office-based physicians in the United States. Sample data are weighted to produce annual national estimates using an estimator that uses a revised nonresponse adjustment. RESULTS: During 2004, an estimated...
Source: Adv Data - June 23, 2006 Category: Epidemiology Authors: Hing E, Cherry DK, Woodwell DA Source Type: journals

National Hospital Ambulatory Medical Care Survey: 2004 outpatient department summary.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This report describes ambulatory care visits to hospital OPDs in the United States. Statistics are presented on selected hospital, patient, and visit characteristics. Selected trends in OPD utilization from 1994 through 2004 are also presented. METHODS: The data presented in this report were collected in the 2004 NHAMCS, a national probability sample survey of visits to emergency and outpatient departments of nonfederal, short-stay, and general hospitals in the United States. Selected comparisons are also made with data from the 2004 National Ambulatory Medical Care Survey (NAMCS), a national probability sample survey of v...
Source: Adv Data - June 23, 2006 Category: Epidemiology Authors: Middleton KR, Hing E Source Type: journals

National Hospital Ambulatory Medical Care Survey: 2004 emergency department summary.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This report describes ambulatory care visits to hospital emergency departments (EDs) in the United States in 2004. Statistics are presented on selected hospital, patient, and visit characteristics. Selected trends in ED utilization from 1994 through 2004 are also presented. METHODS: The data presented in this report were collected in the 2004 National Hospital Ambulatory Medical Care Survey (NHAMCS), a national probability sample survey of visits to emergency and outpatient departments of non-Federal, short-stay, and general hospitals in the United States. Sample data are weighted to produce annual national estimates. RESU...
Source: Adv Data - June 23, 2006 Category: Epidemiology Authors: McCaig LF, Nawar EW Source Type: journals