Obesity - Standards, trends and advances
Adv Med Sci. 2024 Apr 9;69(1):208-215. doi: 10.1016/j.advms.2024.04.001. Online ahead of print.ABSTRACTObesity continues to be a significant global health concern, giving rise to various complications. This review article explores the current standards and emerging innovations in diagnosing and treating obesity, including recent disease name change, staging system or therapeutic goals. This narrative review has been based on recent scientific articles from PubMed database, limiting the scope of topics to current standards and upcoming developments and breakthroughs in the diagnosis and treatment of obesity. The educational...
Source: Advances in Medical Sciences - April 11, 2024 Category: Biomedical Science Authors: Jakub Go łacki Beata Matyjaszek-Matuszek Source Type: research

Obesity - Standards, trends and advances
Adv Med Sci. 2024 Apr 9:S1896-1126(24)00022-1. doi: 10.1016/j.advms.2024.04.001. Online ahead of print.ABSTRACTObesity continues to be a significant global health concern, giving rise to various complications. This review article explores the current standards and emerging innovations in diagnosing and treating obesity, including recent disease name change, staging system or therapeutic goals. This narrative review has been based on recent scientific articles from PubMed database, limiting the scope of topics to current standards and upcoming developments and breakthroughs in the diagnosis and treatment of obesity. The edu...
Source: Advances in Medical Sciences - April 11, 2024 Category: Biomedical Science Authors: Jakub Go łacki Beata Matyjaszek-Matuszek Source Type: research

Impact of NMDA receptors block versus GABA-A receptors modulation on synaptic plasticity and brain electrical activity in metabolic syndrome
CONCLUSIONS: Both Allo and Memantine boosted the outcome parameters in the animal model of MetS. Allo markedly improved the anxiety-like behavior in the form of significantly decreased grooming frequency compared to the Memantine-treated groups. Both drugs were associated with increased hippocampal GFAP and BDNF expression, indicating an improvement in synaptic plasticity and so, cognition-related behaviors.PMID:38561071 | DOI:10.1016/j.advms.2024.03.008 (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - April 1, 2024 Category: Biomedical Science Authors: Shaimaa Nasr Amin Sherif Ahmed Shaltout Walaa Bayoumie El Gazzar Noha Samir Abdel Latif Ghadah Nazar Al-Jussani Yasmeen Jamal Alabdallat Khaled Anwer Albakri Dalia Azmy Elberry Source Type: research

Impact of NMDA receptors block versus GABA-A receptors modulation on synaptic plasticity and brain electrical activity in metabolic syndrome
CONCLUSIONS: Both Allo and Memantine boosted the outcome parameters in the animal model of MetS. Allo markedly improved the anxiety-like behavior in the form of significantly decreased grooming frequency compared to the Memantine-treated groups. Both drugs were associated with increased hippocampal GFAP and BDNF expression, indicating an improvement in synaptic plasticity and so, cognition-related behaviors.PMID:38561071 | DOI:10.1016/j.advms.2024.03.008 (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - April 1, 2024 Category: Biomedical Science Authors: Shaimaa Nasr Amin Sherif Ahmed Shaltout Walaa Bayoumie El Gazzar Noha Samir Abdel Latif Ghadah Nazar Al-Jussani Yasmeen Jamal Alabdallat Khaled Anwer Albakri Dalia Azmy Elberry Source Type: research

Impact of NMDA receptors block versus GABA-A receptors modulation on synaptic plasticity and brain electrical activity in metabolic syndrome
CONCLUSIONS: Both Allo and Memantine boosted the outcome parameters in the animal model of MetS. Allo markedly improved the anxiety-like behavior in the form of significantly decreased grooming frequency compared to the Memantine-treated groups. Both drugs were associated with increased hippocampal GFAP and BDNF expression, indicating an improvement in synaptic plasticity and so, cognition-related behaviors.PMID:38561071 | DOI:10.1016/j.advms.2024.03.008 (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - April 1, 2024 Category: Biomedical Science Authors: Shaimaa Nasr Amin Sherif Ahmed Shaltout Walaa Bayoumie El Gazzar Noha Samir Abdel Latif Ghadah Nazar Al-Jussani Yasmeen Jamal Alabdallat Khaled Anwer Albakri Dalia Azmy Elberry Source Type: research

Impact of NMDA receptors block versus GABA-A receptors modulation on synaptic plasticity and brain electrical activity in metabolic syndrome
CONCLUSIONS: Both Allo and Memantine boosted the outcome parameters in the animal model of MetS. Allo markedly improved the anxiety-like behavior in the form of significantly decreased grooming frequency compared to the Memantine-treated groups. Both drugs were associated with increased hippocampal GFAP and BDNF expression, indicating an improvement in synaptic plasticity and so, cognition-related behaviors.PMID:38561071 | DOI:10.1016/j.advms.2024.03.008 (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - April 1, 2024 Category: Biomedical Science Authors: Shaimaa Nasr Amin Sherif Ahmed Shaltout Walaa Bayoumie El Gazzar Noha Samir Abdel Latif Ghadah Nazar Al-Jussani Yasmeen Jamal Alabdallat Khaled Anwer Albakri Dalia Azmy Elberry Source Type: research

Impact of NMDA receptors block versus GABA-A receptors modulation on synaptic plasticity and brain electrical activity in metabolic syndrome
CONCLUSIONS: Both Allo and Memantine boosted the outcome parameters in the animal model of MetS. Allo markedly improved the anxiety-like behavior in the form of significantly decreased grooming frequency compared to the Memantine-treated groups. Both drugs were associated with increased hippocampal GFAP and BDNF expression, indicating an improvement in synaptic plasticity and so, cognition-related behaviors.PMID:38561071 | DOI:10.1016/j.advms.2024.03.008 (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - April 1, 2024 Category: Biomedical Science Authors: Shaimaa Nasr Amin Sherif Ahmed Shaltout Walaa Bayoumie El Gazzar Noha Samir Abdel Latif Ghada Al-Jussani Yasmeen Jamal Alabdallat Khaled Anwer Albakri Dalia Azmy Elberry Source Type: research

Impact of NMDA receptors block versus GABA-A receptors modulation on synaptic plasticity and brain electrical activity in metabolic syndrome
CONCLUSIONS: Both Allo and Memantine boosted the outcome parameters in the animal model of MetS. Allo markedly improved the anxiety-like behavior in the form of significantly decreased grooming frequency compared to the Memantine-treated groups. Both drugs were associated with increased hippocampal GFAP and BDNF expression, indicating an improvement in synaptic plasticity and so, cognition-related behaviors.PMID:38561071 | DOI:10.1016/j.advms.2024.03.008 (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - April 1, 2024 Category: Biomedical Science Authors: Shaimaa Nasr Amin Sherif Ahmed Shaltout Walaa Bayoumie El Gazzar Noha Samir Abdel Latif Ghada Al-Jussani Yasmeen Jamal Alabdallat Khaled Anwer Albakri Dalia Azmy Elberry Source Type: research

Impact of NMDA receptors block versus GABA-A receptors modulation on synaptic plasticity and brain electrical activity in metabolic syndrome
CONCLUSIONS: Both Allo and Memantine boosted the outcome parameters in the animal model of MetS. Allo markedly improved the anxiety-like behavior in the form of significantly decreased grooming frequency compared to the Memantine-treated groups. Both drugs were associated with increased hippocampal GFAP and BDNF expression, indicating an improvement in synaptic plasticity and so, cognition-related behaviors.PMID:38561071 | DOI:10.1016/j.advms.2024.03.008 (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - April 1, 2024 Category: Biomedical Science Authors: Shaimaa Nasr Amin Sherif Ahmed Shaltout Walaa Bayoumie El Gazzar Noha Samir Abdel Latif Ghada Al-Jussani Yasmeen Jamal Alabdallat Khaled Anwer Albakri Dalia Azmy Elberry Source Type: research

Impact of NMDA receptors block versus GABA-A receptors modulation on synaptic plasticity and brain electrical activity in metabolic syndrome
CONCLUSIONS: Both Allo and Memantine boosted the outcome parameters in the animal model of MetS. Allo markedly improved the anxiety-like behavior in the form of significantly decreased grooming frequency compared to the Memantine-treated groups. Both drugs were associated with increased hippocampal GFAP and BDNF expression, indicating an improvement in synaptic plasticity and so, cognition-related behaviors.PMID:38561071 | DOI:10.1016/j.advms.2024.03.008 (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - April 1, 2024 Category: Biomedical Science Authors: Shaimaa Nasr Amin Sherif Ahmed Shaltout Walaa Bayoumie El Gazzar Noha Samir Abdel Latif Ghada Al-Jussani Yasmeen Jamal Alabdallat Khaled Anwer Albakri Dalia Azmy Elberry Source Type: research

Host genetic variants associated with COVID-19 reconsidered in a Slovak cohort
We present the results of an association study involving hospitalized coronavirus disease 2019 (COVID-19) patients with a clinical background during the 3rd pandemic wave of COVID-19 in Slovakia. Seventeen single nucleotide variants (SNVs) in the eleven most relevant genes, according to the COVID-19 Host Genetics Initiative, were investigated. Our study confirms the validity of the influence of LZTFL1 and 2'-5'-oligoadenylate synthetase (OAS)1/OAS3 genetic variants on the severity of COVID-19. For two LZTFL1 SNVs in complete linkage disequilibrium, rs17713054 and rs73064425, the odds ratios of baseline allelic associations...
Source: Advances in Medical Sciences - March 30, 2024 Category: Biomedical Science Authors: Maria Skerenova Michal Cibulka Zuzana Dankova Veronika Holubekova Zuzana Kolkova Vincent Lucansky Dana Dvorska Andrea Kapinova Michaela Krivosova Martin Petras Eva Baranovicova Ivana Baranova Elena Novakova Peter Liptak Peter Banovcin Anna Bobcakova Rober Source Type: research

Host genetic variants associated with COVID-19 reconsidered in a Slovak cohort
We present the results of an association study involving hospitalized coronavirus disease 2019 (COVID-19) patients with a clinical background during the 3rd pandemic wave of COVID-19 in Slovakia. Seventeen single nucleotide variants (SNVs) in the eleven most relevant genes, according to the COVID-19 Host Genetics Initiative, were investigated. Our study confirms the validity of the influence of LZTFL1 and 2'-5'-oligoadenylate synthetase (OAS)1/OAS3 genetic variants on the severity of COVID-19. For two LZTFL1 SNVs in complete linkage disequilibrium, rs17713054 and rs73064425, the odds ratios of baseline allelic associations...
Source: Advances in Medical Sciences - March 30, 2024 Category: Biomedical Science Authors: Maria Skerenova Michal Cibulka Zuzana Dankova Veronika Holubekova Zuzana Kolkova Vincent Lucansky Dana Dvorska Andrea Kapinova Michaela Krivosova Martin Petras Eva Baranovicova Ivana Baranova Elena Novakova Peter Liptak Peter Banovcin Anna Bobcakova Rober Source Type: research

Host genetic variants associated with COVID-19 reconsidered in a Slovak cohort
We present the results of an association study involving hospitalized coronavirus disease 2019 (COVID-19) patients with a clinical background during the 3rd pandemic wave of COVID-19 in Slovakia. Seventeen single nucleotide variants (SNVs) in the eleven most relevant genes, according to the COVID-19 Host Genetics Initiative, were investigated. Our study confirms the validity of the influence of LZTFL1 and 2'-5'-oligoadenylate synthetase (OAS)1/OAS3 genetic variants on the severity of COVID-19. For two LZTFL1 SNVs in complete linkage disequilibrium, rs17713054 and rs73064425, the odds ratios of baseline allelic associations...
Source: Advances in Medical Sciences - March 30, 2024 Category: Biomedical Science Authors: Maria Skerenova Michal Cibulka Zuzana Dankova Veronika Holubekova Zuzana Kolkova Vincent Lucansky Dana Dvorska Andrea Kapinova Michaela Krivosova Martin Petras Eva Baranovicova Ivana Baranova Elena Novakova Peter Liptak Peter Banovcin Anna Bobcakova Rober Source Type: research

Dendrobium officinale Polysaccharide (DOP) inhibits cell hyperproliferation, inflammation and oxidative stress to improve keratinocyte psoriasis-like state
CONCLUSION: DOP inhibits keratinocyte hyperproliferation, inflammation and oxidative stress to improve the keratinocyte psoriasis-like state.PMID:38521458 | DOI:10.1016/j.advms.2024.03.005 (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - March 23, 2024 Category: Biomedical Science Authors: Bijun Zeng Yining Yan Yujin Zhang Chang Wang Wenting Huang Xinyi Zhong Zi Chen Mengzhou Xie Zhibo Yang Source Type: research

Lymphopenia associated with survivin and its downstream pathway in COVID-19 serving as a potential route in COVID-19 pathogenesis
CONCLUSION: The role of survivin and its related pathway was first discovered in the development of COVID-19 and may serve as a potential prognostic and therapeutic target.PMID:38521459 | DOI:10.1016/j.advms.2024.03.006 (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - March 23, 2024 Category: Biomedical Science Authors: Mohammad Saeed Kahrizi Kamyar Nasiri Farnoosh Ebrahimzadeh Amirhossein Fakhre Yaseri Soroush Ghodratizadeh Mostafa Gholamrezaei Alireza Rahat Dahmardeh Ali Adili Rosita Amjidifar Maryam Hemmatzadeh Mohsen Arabi Mohammad Reza Maghsoudi Hamed Mohammadi Source Type: research