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Successful use of bimatoprost in the treatment of alopecia of the eyelashesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Clinical And Experimental Dermatology)
Source: Clinical And Experimental Dermatology - November 20, 2009 Category: Dermatology Authors: S. Zaheri, B. Hughes Source Type: journals

Presence of a Deletion Mutation (c.716delA) in the Ligand Binding Domain of the Vitamin D Receptor in an Indian Patient with Vitamin D-Dependent Rickets Type IIEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract Vitamin D-dependent rickets type II (VDDR-type II) is a rare disorder caused by mutations in the vitamin D receptor (VDR) gene. Here, we describe a patient with VDDR-type II with severe alopecia and rickets. She had hypocalcemia, hypophosphatemia, secondary hyperparathyroidism, and elevated serum alkaline phosphatase and 1,25-dihydroxyvitamin D3. Sequence analysis of the lymphocyte VDR cDNA revealed deletion mutation c.716delA. Sequence analysis of her genomic DNA fragment amplified from exon 6 of the VDR gene incorporating this mutation confirmed the presence of the mutation in homozygous form. Thi...
Source: Calcified Tissue International - November 17, 2009 Category: Orthopaedics Tags: Calcified Tissue International Source Type: journals

Alefacept for Severe Alopecia Areata: A Randomized, Double-blind, Placebo-Controlled Study [Study]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion Alefacept is ineffective for the treatment of severe AA. (Source: Archives of Dermatology)
Source: Archives of Dermatology - November 16, 2009 Category: Dermatology Authors: Strober, B. E., Menon, K., McMichael, A., Hordinsky, M., Krueger, G., Panko, J., Siu, K., Lustgarten, J. L., Ross, E. K., Shapiro, J. Tags: Dermatology, Dermatologic Disorders, Alopecia, Hair Disorders, Randomized Controlled Trial, Drug Therapy, Drug Therapy, Other Study Source Type: journals

Falluja's babies: The difficulties of pinning the blameEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
War's effects on health can be much harder to identify than death and horrendous physical injuries. The US department of veterans affairs recently accepted that Vietnam war veterans may have developed B cell leukaemias, Parkinson's disease and ischemic heart disease as a result of exposure to a blend of herbicides known as Agent Orange, a defoliating agent sprayed by US warplanes to deprive their enemies of cover.Similarly, ionising radiation from the atomic bombs dropped on Hiroshima and Nagasaki in 1945 led to medical complications such as cancers, nausea, hair loss, bleeding into the skin, inflammation of the mouth and ...
Source: Guardian Unlimited Science - November 13, 2009 Category: Science Authors: Denis Campbell Tags: Iraq Medical research Science The Guardian News World news Source Type: news

Hair LossEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Title: Hair LossCategory: Diseases and ConditionsCreated: 9/24/1999 7:06:00 AMLast Editorial Review: 11/13/2009 (Source: MedicineNet Cancer General)
Source: MedicineNet Cancer General - November 13, 2009 Category: Cancer & Oncology Source Type: consumer

Hair LossEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Title: Hair LossCategory: Diseases and ConditionsCreated: 9/24/1999 7:06:00 AMLast Editorial Review: 11/13/2009 (Source: MedicineNet Mens Health General)
Source: MedicineNet Mens Health General - November 13, 2009 Category: Primary Care Source Type: consumer

Hair LossEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Title: Hair LossCategory: Diseases and ConditionsCreated: 9/24/1999 7:06:00 AMLast Editorial Review: 11/13/2009 (Source: MedicineNet Arthritis General)
Source: MedicineNet Arthritis General - November 13, 2009 Category: Rheumatology Source Type: consumer

Attitudes of dermatologists in the southeastern United States regarding treatment of alopecia areata: a cross-sectional survey study.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Dermatologists' treatment of AA is inconsistent. A stronger evidence base will provide more consistent treatment options. (Source: BMC Dermatology)
Source: BMC Dermatology - November 12, 2009 Category: Dermatology Authors: Niyati MukherjeeDean MorrellMadeleine DuvicPaul StewartLowell Goldsmith Source Type: journals

Herbal medicines/mesoglycan: Alopecia (first report) following mesotherapy?: 2 case reportsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Reactions)
Source: Reactions - November 11, 2009 Category: Drugs & Pharmacology Tags: Short communication Source Type: journals

Tight Turbans Can Cause Premature BaldnessEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Increasing numbers of Sikh men are turning to surgery to reverse hair loss caused by tightly wound turbans. The UK's leading hair transplant specialists - The Farjo Medical Centre - reports that a growing proportion of its patients now come from the male Sikh community. Men as young as 20-years-old are turning to surgery after suffering traction alopecia, caused by turbans pulling on the hair. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 11, 2009 Category: Consumer Health News Tags: Public Health Source Type: news

Tight Turbans Can Cause Premature BaldnessEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Increasing numbers of Sikh men are turning to surgery to reverse hair loss caused by tightly wound turbans. The UK's leading hair transplant specialists - The Farjo Medical Centre - reports that a growing proportion of its patients now come from the male Sikh community. Men as young as 20-years-old are turning to surgery after suffering traction alopecia, caused by turbans pulling on the hair. (Source: Public Health News From Medical News Today)
Source: Public Health News From Medical News Today - November 11, 2009 Category: Primary Care Tags: Public Health Source Type: news

HRQoL changes, mood disorders and satisfaction after treatment in an unselected population of patients with lung cancerEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: The development of many HRQoL parameters after the first treatment modality in an unselected population of patients with primary lung cancer seemed, at large, well correlated to general disease progression and to well-known treatment side effects. However, reduced role function after lung surgery, and reduced anxiety and depression in patients with mood disorders at baseline might be surprising. Patient satisfaction with treatment was surprisingly good. Several findings in this study may help clinicians to improve their handling of patients with lung cancer. Please cite this paper as: Rolke HB, Bakke PS and Gal...
Source: The Clinical Respiratory Journal - November 11, 2009 Category: Respiratory Medicine Authors: Heidi Berg Rolke, Per Sigvald Bakke, Frode Gallefoss Source Type: journals

CHILD syndrome: the NSDHL gene and its role in CHILD syndrome, a rare hereditary disorderEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions This is the first report of CHILD syndrome ever reported in Greece. We suggest that the diagnosis of the syndrome is important for patient information and genetic counselling. (Source: Journal of the European Academy of Dermatology and Venereology)
Source: Journal of the European Academy of Dermatology and Venereology - November 10, 2009 Category: Dermatology Authors: GP Avgerinou, AP Asvesti, AD Katsambas, VA Nikolaou, EC Christofidou, KH Grzeschik, R Happle Source Type: journals

Hypertension and aldosterone levels in women with early-onset androgenetic alopecia.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion A higher prevalence of hypertension in women with androgenetic alopecia has been found. The elevated aldosterone values in these patients may contribute, alongside other mechanisms, to the development of AGA and may also explain the higher prevalence of hypertension. Blood pressure screening of women with AGA will permit earlier diagnosis of an unsuspected hypertension and initiation of appropriate treatment. PMID: 19906217 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - November 10, 2009 Category: Dermatology Authors: Arias-Santiago S, Guiérrez-Salmerón MT, Buendía-Eisman A, Girón-Prieto MS, Naranjo-Sintes R Tags: Br J Dermatol Source Type: journals

Porokeratosis palmaris et plantaris disseminata or a disseminated late-onset variant of porokeratotic eccrine ostial and dermal ductal nevus (PEODDN) with follicular involvement.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A 48-year-old woman presented with a four-year history of pruritic, hyperkeratotic, spiny papules that began on her chest and spread to her extremities, groin, palms, face, and scalp where it caused non-scarring alopecia. Histopathologic features included cornoid lamella, which is the hallmark of porokeratosis. However, the patient's constellation of findings does not meet diagnostic criteria for any of the five clinical variants of porokeratosis. Her presentation is most compatible with either porokeratosis palmaris et plantaris disseminata (PPPD), which is a rare variant of punctate porokeratosis that can involve any...
Source: Dermatol Online J - November 7, 2009 Category: Dermatology Authors: Hartman R, Rizzo C, Patel R, Kamino H, Shupack JL Tags: Dermatol Online J Source Type: journals

Forum Post of the Week: Dealing With Hair LossEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
When nutrition suffers, your hair can suffer, too. A college junior posted in the forum about her hair loss and received some surprisingly practical responses from other readers. Maybe you have experience with losing hair from an eating disorder, or regaining it as your health improved. Join the discussion! Eating disorders' effect on pregnancy Osteoporosis can creep up slowly Bulimia flogs your teeth! Add to Technorati | Free Newsletter | Eating Disorders ForumForum Post of the Week: Dealing With Hair Loss originally appeared on About.com Eating Disorders on Sunday, November 8th, 2009 at 09:17:59.Permalink |...
Source: About.com Eating Disorders - November 7, 2009 Category: Eating Disorders and Weight Management Source Type: consumer

Topical diphencyprone immunotherapy for cutaneous metastatic melanomaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Topical immunotherapy with contact sensitizers for metastatic melanoma was first reported more than 30 years ago. Diphencyprone (DPCP) immunotherapy is frequently used to treat cutaneous warts and alopecia areata, and we have previously reported the use of DPCP as a single agent to successfully treat extensive, radiotherapy-resistant melanoma metastases on the scalp. We now report DPCP treatment of a further six patients with cutaneous metastatic melanoma. Of seven patients treated with DPCP thus far, four have demonstrated complete responses of their cutaneous lesions and three have had partial responses. The treatment wa...
Source: Australasian Journal of Dermatology - November 4, 2009 Category: Dermatology Authors: Diona L Damian, Kerwin F Shannon, Robyn P Saw, John F Thompson Tags: CASE REPORTS AND SMALL CASE SERIES Source Type: journals

Neoadjuvant chemotherapy with a combination of docetaxel, cisplatin, fluorouracil, and leucovorin in nonresectable advanced gastric cancer: a short communicationEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract The aim of this study was to evaluate the efficacy and toxicity of docetaxel (TAX), cisplatin (CDDP), and fluorouracil (5-FU) plus leucovorin (CF) as the neoadjuvant chemotherapy (NACT) regimens in the treatment of nonresectable advanced gastric cancer. Twelve patients with nonresectable advanced gastric cancer were treated with NACT regimens consisted of docetaxel, cisplatin, fluorouracil, plus leucovorin before operation. Nine of the 12 patients were downstaged and 8 were radically operated after the end of the NACT. The overall response rate was 75% with 8.3% complete response and 66.7% partial r...
Source: Medical Oncology - November 3, 2009 Category: Cancer & Oncology Tags: Medical Oncology Source Type: journals

Mitoxantrone: benefits and risks in multiple sclerosis patientsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract Mitoxantrone (MTX) is a synthetic antineoplastic cytotoxic drug, active both on proliferative and non-proliferative cells. The efficacy of MTX has been suggested by many open-label or observational studies and demonstrated in four randomized controlled clinical trials (RCTs). It is indicated for reducing neurological disability and the frequency of clinical relapses in patients with progressive relapsing and worsening relapsing–remitting MS patients. The short-term most frequent adverse events observed in RCTs have been nausea/vomiting, alopecia, an increased risk of urinary and respiratory tract ...
Source: Neurological Sciences - November 3, 2009 Category: Neurology Tags: Neurological Sciences Source Type: journals

Cyclophosphamide as second-line therapy in multiple sclerosis: benefits and risksEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract Cyclophosphamide (Cy) is an alkylating agent used over the past 40 years to halt rapidly progressive forms of multiple sclerosis (MS). High doses of Cy produce marked immunosuppression and an anti-inflammatory immune deviation. Cy is most effective in young patients, with very active MS (frequent relapses, rapid accumulation of disability, and gad+ lesions on brain MRI). Monthly intravenous pulses of Cy for 1 year, followed by bimonthly pulses for the second year are a well-tolerated protocol in MS. Most side effects (mild alopecia, nausea and vomiting, and cystitis) are transient, dose de...
Source: Neurological Sciences - November 3, 2009 Category: Neurology Tags: Neurological Sciences Source Type: journals

Photodynamic therapy with methyl 5-aminolevulinate acid combined with microneedle treatment in patients with extensive alopecia areataEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Clinical And Experimental Dermatology)
Source: Clinical And Experimental Dermatology - November 3, 2009 Category: Dermatology Authors: J. W. Lee, K. H. Yoo, B. J. Kim, M. N. Kim Source Type: journals

Does collapse of immune privilege in the hair-follicle bulge play a role in the pathogenesis of primary cicatricial alopecia?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions. This small series represents our first preliminary attempts to ascertain whether bulge IP collapse may play a role in PCA pathogenesis. We present standard parameters relating to hair-follicle IP in the bulge region of three patients with distinct PCA variants, and show the presence of features consistent with bulge IP collapse in each case. (Source: Clinical And Experimental Dermatology)
Source: Clinical And Experimental Dermatology - November 3, 2009 Category: Dermatology Authors: M. J. Harries, K. C. Meyer, I. H. Chaudhry, C. E. M. Griffiths, R. Paus Source Type: journals

A clinical and epidemiological study of lupus erythmatosus: at a tertiary referral dermatology clinic in korea.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Dermatological examination is critical for the evaluation of lupus erythematosus. However, little is known about the epidemiology and clinical characteristics of the lupus erythematosus patients that visit dermatology clinics with the chief complaint of skin lesions, especially among Asian populations. We performed this study to determine the epidemiology of cutaneous lupus erythematosus for three subtypes: acute cutaneous lupus erythematosus, subacute cutaneous lupus erythematosus, and chronic cutaneous lupus erythematosus, and for lupus erythematosus non-specific skin disease. Also, we sought to determine the relatio...
Source: Lupus - November 2, 2009 Category: Rheumatology Authors: Bae YI, Yun SJ, Lee JB, Kim SJ, Won YH, Lee SC Tags: Lupus Source Type: journals

Four Genes Linked to Alopecia Areata DiscoveredEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
New genetic research is yielding some important clues into the puzzling condition of alopecia areata, Dr. Maria Hordinsky reported at the women's and pediatric dermatology seminar sponsored by Skin Disease Education Foundation (SDEF). (Source: Skin and Allergy News)
Source: Skin and Allergy News - November 1, 2009 Category: Dermatology Authors: ROBERT FINN Tags: Hair & Nails Source Type: journals

Capecitabine in the routine treatment of advanced breast cancer: results from a non-interventional observational study in 870 patients.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: Capecitabine, alone or in combination, is a feasible, effective treatment for breast cancer. Our findings in real-life clinical practice compare favorably with results from interventional studies, perhaps reflecting the longer treatment duration possible at more tolerable doses. PMID: 19887866 [PubMed - in process] (Source: Onkologie)
Source: Onkologie - November 1, 2009 Category: Cancer & Oncology Authors: Siedentopf F, Gohler T, Hesse T, Nusch A, Sulberg H Tags: Onkologie Source Type: journals

Topical diphencyprone immunotherapy for cutaneous metastatic melanoma.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Topical immunotherapy with contact sensitizers for metastatic melanoma was first reported more than 30 years ago. Diphencyprone (DPCP) immunotherapy is frequently used to treat cutaneous warts and alopecia areata, and we have previously reported the use of DPCP as a single agent to successfully treat extensive, radiotherapy-resistant melanoma metastases on the scalp. We now report DPCP treatment of a further six patients with cutaneous metastatic melanoma. Of seven patients treated with DPCP thus far, four have demonstrated complete responses of their cutaneous lesions and three have had partial responses. The treatmen...
Source: The Australasian Journal of Dermatology - November 1, 2009 Category: Dermatology Authors: Damian DL, Shannon KF, Saw RP, Thompson JF Tags: Australas J Dermatol Source Type: journals

Weekly paclitaxel for platin-resistant stage IV head and neck cancer patients.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: Weekly paclitaxel may be an active and well tolerated chemotherapy regimen for patients with platin-resistant advanced head and neck cancer. OBJECTIVES: Weekly paclitaxel should be an active and well tolerated regimen for palliative treatment of platin-resistant patients with recurrent or metastatic carcinoma of the head and neck. We analyzed the antitumor activity and toxicity profile. PATIENTS AND METHODS: Sixty consecutive patients with advanced head and neck cancer were treated with 1 h infusion of paclitaxel, 80 mg/m(2) weekly, for 6 consecutive weeks. Patients who showed disease response or disease stabi...
Source: Acta Oto-Laryngologica - October 31, 2009 Category: ENT & OMF Authors: Grau JJ, Caballero M, Verger E, Monzó M, Blanch JL Tags: Acta Otolaryngol Source Type: journals

Encephalocraniocutaneous lipomatosisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Revised diagnostic criteria are proposed. ECCL is considered to differ from Proteus syndrome in particular, but oculoectodermal syndrome is possibly a mild variant. Pathogenetically, mosaicism for a mutated autosomal gene involved in multiple mesenchymal tumours and vasculogenesis, with or without a second hit event, is discussed. (Source: Journal of Medical Genetics)
Source: Journal of Medical Genetics - October 30, 2009 Category: Genetics & Stem Cells Authors: Moog, U Tags: Molecular genetics, Congenital heart disease, Epilepsy and seizures, Reproductive medicine, Dermatology, Calcium and bone Review Source Type: journals

Mucocutaneous manifestations in 150 HIV-infected Indian patients and their relationship with CD4 lymphocyte countsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Mucocutaneous findings in 150 HIV+ve cases (F, 79; M, 71) were evaluated over a one-year period. Mucocutaneous manifestations were seen in 96% with 2.9 mean number of dermatoses and mean cluster of differentiation (CD4) count of 196.33 cells/mm3. The highest number of mean dermatoses, 3.29, was seen in individuals with severe immunosuppression. The most common mucocutaneous manifestation seen was candidiasis (35.33%), followed by seborrhoeic dermatitis (31.33%), oral pigmentation (29.33%), xerosis/ichthyosis (22.67%), pyodermas (22%), periodontitis (17.33%) and nail pigmentation (16.67%). Patient stratification according t...
Source: International Journal of STD and AIDS - October 30, 2009 Category: Global & Universal Authors: Sud, N, Shanker, V, Sharma, A, Sharma, N L, Gupta, M Tags: Original research articles Source Type: journals

Atypical Progeroid Syndrome due to Heterozygous Missense LMNA Mutations.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: APS patients have a few overlapping but some distinct clinical features as compared with HGPS and mandibuloacral dysplasia. The pathogenesis of clinical manifestations in APS patients seems not to be related to accumulation of mutant farnesylated prelamin A. PMID: 19875478 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism)
Source: The Journal of Clinical Endocrinology and Metabolism - October 29, 2009 Category: Endocrinology Authors: Garg A, Subramanyam L, Agarwal AK, Simha V, Levine B, D'Apice MR, Novelli G, Crow Y Tags: J Clin Endocrinol Metab Source Type: journals

A phase 2 clinical trial of nab-paclitaxel in previously treated and chemotherapy-naive patients with metastatic melanomaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
nab-Paclitaxel (ABI-007, Abraxane), a 130-nM, albumin-bound (nab) particle form of Cremophor-free paclitaxel, is approved for metastatic breast cancer. In the current study, the efficacy and safety of nab-paclitaxel were evaluated in previously treated and chemotherapy-naive patients with metastatic melanoma (MM).Patients with histologically or cytologically confirmed, measurable MM were enrolled. nab-Paclitaxel was administered intravenously weekly for 3 of 4 weeks at a dose of 100 mg/m2 (in previously treated patients) or 150 mg/m2 (in chemotherapy-naive patients).Thirty-seven patients were treated in each cohort. The re...
Source: Cancer - October 28, 2009 Category: Cancer & Oncology Authors: Evan M. Hersh, Steven J. O'Day, Antoni Ribas, Wolfram E. Samlowski, Michael S. Gordon, Deganit E. Shechter, Alicia A. Clawson, Rene Gonzalez Source Type: journals

Serum T helper 1 cytokine levels are greater in patients with alopecia areata regardless of severity or atopyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions. Increased Th1 serum cytokines (IL-2, IL-12 and interferon-[gamma]) and IL-1ra levels are associated with AA regardless of disease severity or the presence of atopy. (Source: Clinical And Experimental Dermatology)
Source: Clinical And Experimental Dermatology - October 22, 2009 Category: Dermatology Authors: N. Barahmani, A. Lopez, D. Babu, M. Hernandez, S. E. Donely, M. Duvic Source Type: journals

Coudability hairs: a revisited sign of alopecia areata assessed by trichoscopyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions. Coudability hairs, more closely perceived by trichoscopy, are useful-markers for disease activity in AA and provide a surrogate-marker for the hair-pull test. (Source: Clinical And Experimental Dermatology)
Source: Clinical And Experimental Dermatology - October 22, 2009 Category: Dermatology Authors: S. Inui, T. Nakajima, S. Itami Source Type: journals

The effect and side effects of Gemcitabine plus Vinorelbine in patients with triple-negative metastatic breast cancerEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion The combination of GEM and NVB is an effective and well tolerated regimen for the patients with TNABC. Content Type Journal ArticleDOI 10.1007/s10330-009-0147-yAuthors Chen Yang, Shanghai Jiaotong University Department of Medical oncology, Sixth People’s Hospital Shanghai 200233 ChinaZhiyu Wang, Shanghai Jiaotong University Department of Medical oncology, Sixth People’s Hospital Shanghai 200233 ChinaYang Yao, Shanghai Jiaotong University Department of Medical oncology, Sixth People’s Hospital Shanghai 200233 ChinaXiaojie Bian, Shanghai Jiaotong University Department of Medical oncology,...
Source: The Chinese-German Journal of Clinical Oncology - October 21, 2009 Category: Cancer & Oncology Tags: The Chinese-German Journal of Clinical Oncology Source Type: journals

Demodex gatoi -associated contagious pruritic dermatosis in cats - a report from six households in FinlandEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: D. gatoi-associated dermatitis is an emerging contagious skin disease in cats in Finland. Although pruritus is common, some cats may harbour the mites without clinical signs. In addition, due to translucency of the mites and fastidious feline grooming habits, the diagnosis may be challenging. An effective and convenient way to treat D. gatoi infestations has yet to emerge. (Source: Acta Veterinaria Scandinavica)
Source: Acta Veterinaria Scandinavica - October 19, 2009 Category: Veterinary Research Authors: Seppo SaariKirsi JuutiJoanna PalojarviKirsi VaisanenRiitta-Liisa RajaniemiLeena Saijonmaa-Koulumies Source Type: journals

STUDY: Practical Guidelines for Evaluation of Loose Anagen Hair SyndromeEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions Loose anagen hair syndrome is a common nonscarring alopecia in young girls with a history of sparse or fine hair. Before ordering extensive blood testing in young girls with diffusely thin hair, it is important to perform a hair-pull test, as a trichogram can be instrumental in the confirmation of a diagnosis of LAHS. (Source: Archives of Dermatology)
Source: Archives of Dermatology - October 19, 2009 Category: Dermatology Authors: Cantatore-Francis, J. L., Orlow, S. J. Tags: Dermatology, Dermatologic Disorders, Alopecia, Pediatrics, Pediatrics, Other, Hair Disorders, Dermatologic Disorders, Other Study Source Type: journals

Practical Guidelines for Evaluation of Loose Anagen Hair Syndrome [Study]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions Loose anagen hair syndrome is a common nonscarring alopecia in young girls with a history of sparse or fine hair. Before ordering extensive blood testing in young girls with diffusely thin hair, it is important to perform a hair-pull test, as a trichogram can be instrumental in the confirmation of a diagnosis of LAHS. (Source: Archives of Dermatology)
Source: Archives of Dermatology - October 19, 2009 Category: Dermatology Authors: Cantatore-Francis, J. L., Orlow, S. J. Tags: Dermatology, Dermatologic Disorders, Alopecia, Pediatrics, Pediatrics, Other, Hair Disorders, Dermatologic Disorders, Other Study Source Type: journals

Review paper The most common diseases of scalp in childhoodEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The total and partial lack of hair growth occurs in the form of several clinical forms, either as an isolated defect or in connection with many kinds of abnormalities. Logical classification should be based on careful histopathological and genetic studies, but such studies are, unfortunately, rarely carried out. Hair microscopic examination is necessary in cases of abnormal hair, regardless of the quantitative which was on the scalp and it should be carefully sought for other ektodermal defects and examination of the patients relatives. Congenital alopecia may be partial or total. I the moment of the damage the condition o...
Source: Articles of Advances in Dermatology and Allergology - TERMEDIA publishing house - October 19, 2009 Category: Dermatology Source Type: journals

Weekly Paclitaxel and Cisplatin in the Treatment of Elderly Advanced Non-small Cell Lung CancerEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion The patients of advanced NSCLC more than 70 years old can tolerate weekly paclitaxel and cisplatin and can get benefit from this regiment. (Source: Chinese Journal of Lung Cancer)
Source: Chinese Journal of Lung Cancer - October 19, 2009 Category: Cancer & Oncology Source Type: journals

Satoyoshi syndrome with unusual skeletal abnormalities and parental consanguinityEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We describe a 26-year-old Mexican woman, a product of consanguineous parents with clinical characteristics of SS. Our patient, also showed skeletal anomalies not previously reported that seems to be a coincidental finding. © 2009 Wiley-Liss, Inc. (Source: American Journal of Medical Genetics Part A)
Source: American Journal of Medical Genetics Part A - October 15, 2009 Category: Genetics & Stem Cells Authors: C.A. Venegas-Vega, M.R. Rivera-Vega, S. Cuevas-Covarrubias, J. Orozco, S. Kofman-Alfaro Source Type: journals

4 patients say Cedars-Sinai did not tell them they had received a radiation overdoseEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The hospital says it contacted all 206 patients affected by the CT scan error. But some tell The Times they were only asked about hair loss and not told of the mistake or its potential cancer risk. Cedars-Sinai Medical Center did not tell all 206 patients who received radiation overdoses during CT scans of the hospital's error, according to the accounts of four people who said they only came to understand what happened to them through news reports. (Source: Los Angeles Times - Science)
Source: Los Angeles Times - Science - October 15, 2009 Category: Science Source Type: news

A randomized, phase III multicenter trial of gemcitabine in combination with carboplatin or paclitaxel versus paclitaxel plus carboplatin in patients with advanced or metastatic non-small-cell lung cancer.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: Non-platinum and non-paclitaxel gemcitabine-containing doublets demonstrate similar overall survival and RR compared with the standard PC regimen. However, the treatment arms had distinct toxicity profiles. PMID: 19833819 [PubMed - as supplied by publisher] (Source: Ann Oncol)
Source: Ann Oncol - October 14, 2009 Category: Cancer & Oncology Authors: Treat JA, Gonin R, Socinski MA, Edelman MJ, Catalano RB, Marinucci DM, Ansari R, Gillenwater HH, Rowland KM, Comis RL, Obasaju CK, Belani CP, Tags: Ann Oncol Source Type: journals

The performance of doxorubicin encapsulated in chitosan-dextran sulphate microparticles in an osteosarcoma model.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Osteosarcoma (OS) is the most common primary bone cancer affecting children and adolescents. It is potentially debilitating and fatal due to pulmonary metastasis. A common management strategy, chemotherapy, has a 10-year disease-free survival of approximately 60%. However, a targeted approach to OS tumor inhibition is still lacking, calling for improved management strategies. A frontline drug for OS, doxorubicin (DOX), causes multiple side-effects (example myelosuppression, heart failure, hepatic toxicity, alopecia) in patients, especially in high doses required to control tumor growth. A drug delivery system (DDS) was...
Source: Biomaterials - October 14, 2009 Category: Materials Science Authors: Tan ML, Friedhuber AM, Dunstan DE, Choong PF, Dass CR Tags: Biomaterials Source Type: journals

MicroRNAs take part in pathophysiology and pathogenesis of Male Pattern Baldness.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Male Pattern Baldness (MPB) or androgenetic alopecia is a common form of hair loss with androgens and genetics having etiological significance. Androgens are thought to pathophysiologically power on cascades of chronically dramatic alterations in genetically susceptible scalp dermal papillas, specialized cells in hair follicles in which androgens react, and finally resulting in a patterned alopecia. However, the exact mechanisms through which androgens, positive regulators of growth and anabolism in most body sites, paradoxically exert their effects on balding hair follicles, are not yet known. The role of microRNAs, a...
Source: Molecular Biology Reports - October 9, 2009 Category: Molecular Biology Authors: Goodarzi HR, Abbasi A, Saffari M, Tabei MB, Noori Daloii MR Tags: Mol Biol Rep Source Type: journals

Genetic Baldness Test Complies With The European Directive On In Vitro Diagnostic Medical DevicesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The HairDX Genetic Test for Hair Loss, the world's first genetic baldness (Androgenetic Alopecia) test, is now available as a CE Marked product under the European In Vitro Diagnostic Directive. The announcement was made at the 18th European Academy of Dermatology and Venereology (EADV) Congress in Berlin today by pharmacogenomics research and development innovator PharmaGenoma, Inc. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - October 9, 2009 Category: Consumer Health News Tags: Dermatology Source Type: news

Tailor-made wig styling will give boost to thousands of cancer patients in the UKEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Hundreds of hairdressers are giving new hope to women suffering hair loss after cancer treatment. (Source: the Mail online | Health)
Source: the Mail online | Health - October 9, 2009 Category: Consumer Health News Source Type: news

Weekly administration of docetaxel and epirubicin as first-line treatment for hormone-refractory prostate carcinoma.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Androgen-independent prostate carcinoma (AICP) is one of the tumors that continue to respond poorly to chemotherapy. Recently, protocols based on the use of docetaxel have significantly improved survival for patients in this disease. In other types of neoplastic disease, combined therapy with taxanes and anthracycline derivatives has been shown to produce additive effects in terms of growth inhibition, and superior tolerability when associated with weekly administration schedules. These findings prompted us to examine the tolerability and efficacy of weekly treatment of AICP with docetaxel (DOX) plus epirubicin (EPI). ...
Source: Oncology Research - October 9, 2009 Category: Cancer & Oncology Authors: Neri B, Molinara E, Pantaleo P, Rangan S, Crisci A, Della Melina A, Raugei A, Villari D, Nicitat G Tags: Oncol Res Source Type: journals

Hair loss advice project extendedEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Hairdressers are to receive more training to help cancer patients deal with hair loss and to learn how to style wigs to look natural. (Source: BBC News | Health | UK Edition)
Source: BBC News | Health | UK Edition - October 9, 2009 Category: Consumer Health News Tags: Health Source Type: news

Do neurooncological patients and their significant others agree on quality of life ratings?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: The assessment of quality of life in brain cancer patients through ratings from their significant others seems to be a feasible strategy to gain information about certain aspects of patient's quality of life and symptom burden, if the patient is not able to provide information himself. (Source: BioMed Central)
Source: BioMed Central - October 8, 2009 Category: Journals (General) Authors: Johannes GiesingerMiriam GolserAstrid ErharterGeorg KemmlerGabriele Schauer-MaurerGuenter StockhammerArmin MuiggMarkus HuttererGerhard RumpoldBernhard Holzner Source Type: journals

Modulation of Vitamin D Receptor Activity by the Corepressor Hairless: Differential Effects of Hairless Isoforms.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In conclusion, we have demonstrated that both HR isoforms are expressed in keratinocytes and that the HRDelta1072-1126 isoform lacks corepressor activity and is unable to bind HDACs. HRDelta1072-1126 may function as a coactivator in some settings by inhibiting HDAC recruitment to the VDR transcriptional complex. PMID: 19819974 [PubMed - as supplied by publisher] (Source: Endocrinology)
Source: Endocrinology - October 8, 2009 Category: Endocrinology Authors: Malloy PJ, Wang J, Jensen K, Feldman D Tags: Endocrinology Source Type: journals