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Pulling the plug on grandma.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19803546 [PubMed - in process] (Source: Alternative Medicine Review)
Source: Alternative Medicine Review - August 31, 2009 Category: Complementary Medicine Authors: Czap A Tags: Altern Med Rev Source Type: journals

Maternal levels of xenobiotics that affect fetal development and childhood health.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This article discusses the effect of xenobiotics on fetal and child health, essential information for any health care provider working with women of childbearing age. Recommendations for maternal testing and dietary changes to avoid the greatest sources of exposure are also included. PMID: 19803547 [PubMed - in process] (Source: Alternative Medicine Review)
Source: Alternative Medicine Review - August 31, 2009 Category: Complementary Medicine Authors: Crinnion WJ Tags: Altern Med Rev Source Type: journals

Bioavailability and activity of phytosome complexes from botanical polyphenols: the silymarin, curcumin, green tea, and grape seed extracts.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Plant-derived polyphenols are increasingly receiving attention as dietary supplements for the homeostatic management of inflammation, to support detoxication, and for anticancer, weight loss, and other benefits. Their pro-homeostatic effects on genes, transcription factors, enzymes, and cell signaling pathways are being intensively explored, but the poor bioavailability of some polyphenols likely contributes to poor clinical trial outcomes. This review covers four polyphenol preparations with poor bioavailability and their complexation into phytosomes to bypass this problem. Silybin and the other silymarin flavonoligna...
Source: Alternative Medicine Review - August 31, 2009 Category: Complementary Medicine Authors: Kidd PM Tags: Altern Med Rev Source Type: journals

Digestive and nutritional considerations in celiac disease: could supplementation help?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Due to the increased immune activation in the intestinal tract of people with celiac disease, the digestive and absorptive processes of those affected may be compromised. Individuals with celiac disease are more susceptible to pancreatic insufficiencies, dysbiosis, lactase insufficiencies, and folic acid, vitamin B12, iron, and vitamin D deficiencies, as well as accelerated bone loss due to an increase in inflammatory signaling molecules. Beyond strict maintenance of a gluten-free diet, research has shown benefit with additional nutritional supplementation to assist in regulation of several of these complications. ...
Source: Alternative Medicine Review - August 31, 2009 Category: Complementary Medicine Authors: Malterre T Tags: Altern Med Rev Source Type: journals

Nutritional approaches to prevention and treatment of gallstones.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Cholesterol gallstones are among the most common gastrointestinal disorders in Western societies. Individuals with gallstones may experience various gastrointestinal symptoms and are also at risk of developing acute or chronic cholecystitis. Cholecystectomy is the most frequently recommended conventional treatment for symptomatic gallstones. Bile acids (ursodeoxycholic acid or chenodeoxycholic acid) are also used in some cases to dissolve radiolucent stones, but these drugs can cause gastrointestinal side effects and there is a high rate of stone recurrence after treatment is discontinued. Lithotripsy is used in some c...
Source: Alternative Medicine Review - August 31, 2009 Category: Complementary Medicine Authors: Gaby AR Tags: Altern Med Rev Source Type: journals

Potential physiological importance of pyrroloquinoline quinone.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Pyrroloquinoline quinone (PQQ) is a novel biofactor for which a proposition can be made for physiological importance. PQQ was first recognized as an enzyme cofactor in bacteria. It has recently been tentatively identified as a component of interstellar dust. Thus, PQQ may have been present throughout early biological conception and evolution. PQQ is also a potent plant growth factor. Consequently, for animals and humans, there has been constant exposure to PQQ. In animals, PQQ is reported to participate in a range of biological functions with apparent survival benefits (e.g., improved neonatal growth and reproductive p...
Source: Alternative Medicine Review - August 31, 2009 Category: Complementary Medicine Authors: Rucker R, Chowanadisai W, Nakano M Tags: Altern Med Rev Source Type: journals

Aesculus hippocastanum (Horse chestnut) - Monograph.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Authors: Aesculus hippocastanum (horse chestnut) is a large deciduous, rapidly-growing tree that can reach a height of 36 meters. Historically, the seed extract was used as a treatment for many ailments, including rheumatism, rectal complaints, bladder and gastrointestinal disorders, fever (first written account in 1720), hemorrhoids (as early as 1886), and leg cramps. Currently, horse chestnut seed extract (HCSE) is widely used in Europe for chronic venous insufficiency, hemorrhoids, post-operative edema, and topically for clearing skin conditions. In the United States, HCSE is gaining wider acceptance as an effectiv...
Source: Alternative Medicine Review - August 31, 2009 Category: Complementary Medicine Tags: Altern Med Rev Source Type: journals

Vitamin k2 - monograph.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Authors: Vitamin K is a fat-soluble vitamin essential for the functioning of several proteins involved in blood clotting. Discovered in 1929 by Danish scientist Henrik Dam, the vitamin received the letter K because the initial discoveries were reported in a German journal in which the substance was designated as Koagulationsvitamin. Research during the last 30 years has resulted in greater appreciation for vitamin K. For instance, although vitamin K is usually identified as a critical factor in blood coagulation, recent research reveals it is a cofactor in bone metabolism. Inhibition of cancerous cell growth in vivo a...
Source: Alternative Medicine Review - August 31, 2009 Category: Complementary Medicine Tags: Altern Med Rev Source Type: journals

The Problem with the Double-edged Solution.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19594219 [PubMed - in process] (Source: Alternative Medicine Review)
Source: Alternative Medicine Review - May 31, 2009 Category: Complementary Medicine Authors: Czap A Tags: Altern Med Rev Source Type: journals

Study suggests antioxidants inhibit exercise-induced insulin sensitivity.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19594220 [PubMed - in process] (Source: Alternative Medicine Review)
Source: Alternative Medicine Review - May 31, 2009 Category: Complementary Medicine Authors: Head KA Tags: Altern Med Rev Source Type: journals

The benefit of pre- and post-challenge urine heavy metal testing: Part 2.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Measuring heavy metal levels in the urine is an accepted method for assessing the presence of a heavy metal burden in an individual. Random samples (without a flushing agent) are excellent for showing current exposures, as they reflect the level of heavy metals in the bloodstream during the hours immediately before bladder voiding. Samples taken after using a heavy metal mobilizing agent are a reflection of total body burden. Part 1 reviewed the benefits of doing pre-flush (baseline) testing utilizing the published Centers for Disease Control (CDC) heavy metal normal ranges for interpretation that allow the clinician t...
Source: Alternative Medicine Review - May 31, 2009 Category: Complementary Medicine Authors: Crinnion WJ Tags: Altern Med Rev Source Type: journals

Nutrients and botanicals for treatment of stress: adrenal fatigue, neurotransmitter imbalance, anxiety, and restless sleep.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This article focuses on the use of nutrients and botanicals to support the adrenals, balance neurotransmitters, treat acute anxiety, and support restful sleep. PMID: 19594222 [PubMed - in process] (Source: Alternative Medicine Review)
Source: Alternative Medicine Review - May 31, 2009 Category: Complementary Medicine Authors: Head KA, Kelly GS Tags: Altern Med Rev Source Type: journals

Greenselect Phytosome as an adjunct to a low-calorie diet for treatment of obesity: a clinical trial.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A recently developed oral formulation in the form of coated tablets (Monoselect Camellia) (MonCam) containing highly bioavailable green tea extract (GreenSelect Phytosome) was tested in obese subjects (n=100) of both genders on a hypocaloric diet. Fifty subjects were assigned to the green tea extract plus hypocaloric diet, while the other 50 subjects followed the hypocaloric diet only. After 90 days of treatment, significant weight loss and decreased body mass index (BMI) were observed in the group taking the herbal extract (14-kg loss in the green tea group compared to a 5-kg loss in the diet-only group); waistline wa...
Source: Alternative Medicine Review - May 31, 2009 Category: Complementary Medicine Authors: Di Pierro F, Menghi AB, Barreca A, Lucarelli M, Calandrelli A Tags: Altern Med Rev Source Type: journals

Evaluation of cardioprotective activity of Ginkgo biloba and Ocimum sanctum in rodents.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This study investigates the cardioprotective activity of a combined treatment of Ginkgo biloba phytosomes (GBP) and Ocimum sanctum extract (Os) in isoproterenol (ISO)-induced myocardial necrosis in rats. Significant myocardial necrosis, depletion of the endogenous antioxidants superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx), glutathione reductase (GR), and glutathione (GSH), and increases in the serum marker enzymes aspartate aminotransferase (AST), lactate dehydrogenase (LDH), and creatine phosphokinase (CPK) were observed in ISO-treated rats compared with normal rats. Co-administration of GBP (10...
Source: Alternative Medicine Review - May 31, 2009 Category: Complementary Medicine Authors: Panda VS, N SR Tags: Altern Med Rev Source Type: journals

Panax ginseng - Monograph.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Authors: Panax ginseng, used medicinally for thousands of years in China, Korea, and Japan, is well known as an adaptogen and a restorative tonic that is widely used in traditional Chinese medicine (TCM) and Western herbal preparations. Eclectic uses for Panax ginseng include fatigue, infertility, liver disease, amnesia, colds, menopause, and erectile dysfunction. There are many species of Panax, which leads to some confusion in the literature. However, the two species that have been the most extensively researched and used are Panax ginseng and Panax quinquefolius. Another botanical species, although commonly called ...
Source: Alternative Medicine Review - May 31, 2009 Category: Complementary Medicine Tags: Altern Med Rev Source Type: journals

Vanadium (vanadyl sulfate) - monograph.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Authors: The chemical element vanadium was first discovered by Spanish-born Mexican mineralogist, Andrés Manuel del Río, in 1801. He originally named the element panchromium because of the spectrum of colors associated with various oxides of the metal, but changed the name to erythronium, because most of the mineral salts turned red upon heating. Later, del Rio was convinced by fellow scientists that he had really found impure chromium and not a new element. To his regret, that same element was rediscovered 30 years later by Swedish chemist, Nils Gabriel Sefstrom, who named it vanadium, after the Nordic godd...
Source: Alternative Medicine Review - May 31, 2009 Category: Complementary Medicine Tags: Altern Med Rev Source Type: journals

The benefits of pre- and post-challenge urine heavy metal testing: Part 1.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Measuring urine heavy metals is an accepted method for assessing the presence of these toxins in an individual. A random sample (without a flushing agent) is excellent for showing current exposures because it reflects the level of heavy metals in the bloodstream during the hours immediately before bladder voiding. A sample taken after using a heavy-metal-mobilizing agent provides a reflection of total body burden. By utilizing both pre- and post-flush testing, the clinician gains information that cannot be acquired by other means, including identification of current exposures to lead and mercury - critical for proper t...
Source: Alternative Medicine Review - March 1, 2009 Category: Complementary Medicine Authors: Crinnion WJ Tags: Altern Med Rev Source Type: journals

Integrated brain restoration after ischemic stroke--medical management, risk factors, nutrients, and other interventions for managing inflammation and enhancing brain plasticity.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Brain injury from ischemic stroke can be devastating, but full brain restoration is feasible. Time until treatment is critical; rapid rate of injury progression, logistical and personnel constraints on neurological and cardiovascular assessment, limitations of recombinant tissue plasminogen activator (rtPA) for thrombolysis, anticoagulation and antiplatelet interventions, and neuroprotection all affect outcome. Promising acute neuroprotectant measures include albumin, magnesium, and hypothermia. Long-term hyperbaric oxygen therapy (HBOT) is safe and holds great promise. Eicosanoid and cytokine down-regulation by omega-...
Source: Alternative Medicine Review - March 1, 2009 Category: Complementary Medicine Authors: Kidd PM Tags: Altern Med Rev Source Type: journals

Inulin-type prebiotics: a review. (Part 2).Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This article discusses the clinical research on inulin-type prebiotics, including effects on infant nutrition, gastrointestinal health, colon cancer prevention, blood sugar and lipid metabolism, bone mineralization, fatty liver disease, obesity, and immunity. Gastrointestinal side effects and dosage recommendations are also considered. PMID: 19364192 [PubMed - indexed for MEDLINE] (Source: Alternative Medicine Review)
Source: Alternative Medicine Review - March 1, 2009 Category: Complementary Medicine Authors: Kelly G Tags: Altern Med Rev Source Type: journals

EDTA chelation therapy, without added vitamin C, decreases oxidative DNA damage and lipid peroxidation.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Chelation therapy is thought to not only remove contaminating metals but also to decrease free radical production. However, in standard ethylene diamine tetracetic acid (EDTA) chelation therapy, high doses of vitamin C with potential pro-oxidant effects are often added to the chelation solution. The authors demonstrated previously that the intravenous administration of the standard chelation cocktail, containing high amounts of vitamin C, resulted in an acute transitory pro-oxidant burst that should be avoided in the treatment of pathologies at risk of increased oxidative stress such as diabetes and cardiovascular dise...
Source: Alternative Medicine Review - March 1, 2009 Category: Complementary Medicine Authors: Roussel AM, Hininger-Favier I, Waters RS, Osman M, Fernholz K, Anderson RA Tags: Altern Med Rev Source Type: journals

Olive leaf. Monograph.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Authors: PMID: 19364194 [PubMed - indexed for MEDLINE] (Source: Alternative Medicine Review)
Source: Alternative Medicine Review - March 1, 2009 Category: Complementary Medicine Tags: Altern Med Rev Source Type: journals

Vitex agnus-castus. Monograph.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Authors: PMID: 19364195 [PubMed - indexed for MEDLINE] (Source: Alternative Medicine Review)
Source: Alternative Medicine Review - March 1, 2009 Category: Complementary Medicine Tags: Altern Med Rev Source Type: journals

Is modified citrus pectin an effective mobilizer of heavy metals in humans?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19238763 [PubMed - in process] (Source: Alternative Medicine Review)
Source: Alternative Medicine Review - December 1, 2008 Category: Complementary Medicine Authors: Crinnion W Tags: Altern Med Rev Source Type: journals

Successful treatment of schizophrenia requires optimal daily doses of vitamin B3.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19238764 [PubMed - in process] (Source: Alternative Medicine Review)
Source: Alternative Medicine Review - December 1, 2008 Category: Complementary Medicine Authors: Hoffer A, Prousky J Tags: Altern Med Rev Source Type: journals

Inulin-type prebiotics--a review: part 1.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This article is part 1 of a two-part review of inulin-type prebiotics. Prebiotics are a category of nutritional compounds grouped together by the ability to promote the growth of specific beneficial (probiotic) gut bacteria. Inulin-type prebiotics contain fructans of the inulin-type. Fructans are a category of nutritional compounds that encompasses naturally occurring plant oligo- and polysaccharides in which one or more fructosyl-fructose linkages comprise the majority of glycosidic bonds. To be inulin-type a fructan must have beta (2(1) fructosyl-fructose glycosidic bonds, which gives inulin its unique structural and phy...
Source: Alternative Medicine Review - December 1, 2008 Category: Complementary Medicine Authors: Kelly G Tags: Altern Med Rev Source Type: journals

Additive activity of royal jelly and honey against Pseudomonas aeruginosa.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
As natural products garner attention in the medical field, the emergence of antibiotic-resistant strains of bacteria has confounded the current use of antibiotic therapy, leading to the re-examination of earlier remedies such as honey and royal jelly (RJ). Four varieties of honey and one variety of freshly reaped RJ were used to evaluate the additive antimicrobial action against Pseudomonas aeruginosa (ATCC 27853). Initially, honey and RJ were used separately to determine their minimum inhibitory concentration (MIC) against the tested strain. Next, sub-MIC concentrations of honey and RJ were incorporated into media to ...
Source: Alternative Medicine Review - December 1, 2008 Category: Complementary Medicine Authors: Boukraa L Tags: Altern Med Rev Source Type: journals

Riboflavin. Monograph.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Authors: PMID: 19152481 [PubMed - in process] (Source: Alternative Medicine Review)
Source: Alternative Medicine Review - December 1, 2008 Category: Complementary Medicine Tags: Altern Med Rev Source Type: journals

Whey protein. Monograph.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Authors: PMID: 19152482 [PubMed - in process] (Source: Alternative Medicine Review)
Source: Alternative Medicine Review - December 1, 2008 Category: Complementary Medicine Tags: Altern Med Rev Source Type: journals

Clinical applications of urinary organic acids. Part 2. Dysbiosis markers.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Part 1 of this series focused on urinary organic acids as markers of detoxification; part 2 focuses on dysbiosis markers. Intestinal microbial growth is accompanied by the release of products of their metabolism that may be absorbed and excreted in urine. Several organic acids are known to be specific products of bacterial metabolic action on dietary polyphenols or unassimilated amino acids or carbohydrates. Associated gastrointestinal or neurological symptoms may result from irritation of the intestinal mucosa or systemic distribution of absorbed neurotoxic products. Detection of abnormally elevated levels of these pr...
Source: Alternative Medicine Review - December 1, 2008 Category: Complementary Medicine Authors: Lord RS, Bralley JA Tags: Altern Med Rev Source Type: journals

The role of enzyme supplementation in digestive disorders.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This article reviews various forms of enzyme supplementation used clinically in digestive and absorption disorders. Enzyme supplementation plays an integral role in the management of various digestive disorders, particularly with regard to exocrine pancreatic insufficiency. However, application of enzymes may also be beneficial for other conditions associated with poor digestion including lactose intolerance. Historically, porcine and bovine pancreatic enzymes have been the preferred form of supplementation for exocrine pancreatic insufficiency. Use of microbe-derived lipase has shown promise with studies indicating benefi...
Source: Alternative Medicine Review - December 1, 2008 Category: Complementary Medicine Authors: Roxas M Tags: Altern Med Rev Source Type: journals

Inulin-type prebiotics - a review: part 1.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This article is part 1 of a two-part review of inulin-type prebiotics. Prebiotics are a category of nutritional compounds grouped together by the ability to promote the growth of specific beneficial (probiotic) gut bacteria. Inulin-type prebiotics contain fructans of the inulin-type. Fructans are a category of nutritional compounds that encompasses naturally occurring plant oligo- and polysaccharides in which one or more fructosyl-fructose linkages comprise the majority of glycosidic bonds. To be inulin-type a fructan must have beta (2(1) fructosyl-fructose glycosidic bonds, which gives inulin its unique structural and phy...
Source: Alternative Medicine Review - December 1, 2008 Category: Complementary Medicine Authors: Kelly G Tags: Altern Med Rev Source Type: journals

Additive activity of royal jelly and honey against Psuedomonas aeruginosa.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
As natural products garner attention in the medical field, the emergence of antibiotic-resistant strains of bacteria has confounded the current use of antibiotic therapy, leading to the re-examination of earlier remedies such as honey and royal jelly (RJ). Four varieties of honey and one variety of freshly reaped RJ were used to evaluate the additive antimicrobial action against Pseudomonas aeruginosa (ATCC 27853). Initially, honey and RJ were used separately to determine their minimum inhibitory concentration (MIC) against the tested strain. Next, sub-MIC concentrations of honey and RJ were incorporated into media to ...
Source: Alternative Medicine Review - December 1, 2008 Category: Complementary Medicine Authors: Boukraa L Tags: Altern Med Rev Source Type: journals

Riboflavin - monograph.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Authors: Riboflavin was originally recognized as a growth factor in 1879 and named vitamin B2 according to the British nomenclature system. It was first isolated from egg whites in 1934 and synthesized in 1935. Riboflavin fluoresces yellow-orange and gives the yellow-white hue to egg whites and milk. Riboflavin has two active coenzyme forms, riboflavin 5'-phosphate (R5P; flavin mononucleotide [FMN]) and flavin adenine dinucleotide (FAD). Dietary sources include milk, eggs, meats, yogurt, broccoli, almonds, cheese, soy, fortified grains, and dark green vegetables, in descending order of concentration. Normal colonic ba...
Source: Alternative Medicine Review - December 1, 2008 Category: Complementary Medicine Tags: Altern Med Rev Source Type: journals

Whey protein - monograph.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Authors: In recent years, milk constituents have become recognized as functional foods, suggesting their use has a direct and measurable effect on health outcomes. Whey, a by-product of cheese and curd manufacturing, was once considered a waste product. The recognition of whey as a functional food with nutritional applications has elevated whey to a co-product in the manufacturing of cheese. The two primary sources of protein in milk are the caseins and whey. After processing occurs, the caseins are the proteins responsible for making curds, while whey remains in an aqueous environment. The components of whey include ...
Source: Alternative Medicine Review - December 1, 2008 Category: Complementary Medicine Tags: Altern Med Rev Source Type: journals

Natural approaches to prevention and treatment of infections of the lower urinary tract.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Infections of the lower urinary tract are common occurrences in young women, during pregnancy, and in peri- and postmenopausal women. Because of the chronic nature of urinary tract infections (UTIs) and the potential for antibiotic resistance, a natural approach to prevention and treatment is desirable. Clinical research suggests the best natural options for long-term prevention include cranberry, mannose, and probiotics. Botanicals that can be effective at the first sign of an infection and for short-term prophylaxis include berberine and uva ursi. Estriol cream and vitamins A and C have also been shown to prevent UTI...
Source: Alternative Medicine Review - September 1, 2008 Category: Complementary Medicine Authors: Head KA Tags: Altern Med Rev Source Type: journals

Phosphatidylserine. Monograph.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Authors: PMID: 18950250 [PubMed - in process] (Source: Alternative Medicine Review)
Source: Alternative Medicine Review - September 1, 2008 Category: Complementary Medicine Tags: Altern Med Rev Source Type: journals

Harpagophytum procumbens (devil's claw). Monograph.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Authors: PMID: 18950251 [PubMed - in process] (Source: Alternative Medicine Review)
Source: Alternative Medicine Review - September 1, 2008 Category: Complementary Medicine Tags: Altern Med Rev Source Type: journals

Nutritional therapies for ocular disorders: Part Three.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Parts one and two of this series discussed nutritional and botanical treatments for cataracts, glaucoma, and retinal diseases (macular degeneration, diabetic retinopathy, retinopathy of the newborn, and retinitis pigmentosa). This review discusses nutritional treatments for asthenopia, blepharitis, chalazion, conjunctivitis (including giant papillary conjunctivitis), gyrate atrophy of the choroid and retina, keratoconus, myopia, sicca syndrome (dry eyes), and uveitis. The evidence presented in this three-part series indicates natural medicine has an important role to play in the practice of ophthalmology. PMID: 189...
Source: Alternative Medicine Review - September 1, 2008 Category: Complementary Medicine Authors: Gaby AR Tags: Altern Med Rev Source Type: journals

Clinical applications of urinary organic acids. Part I: Detoxification markers.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Modern instrumentation allows the measurement of organic acids in urine in their physiological concentration ranges. Eight of the compounds that are reported can serve as markers for specific toxicant exposure or detoxification challenges. Xylene exposure causes elevation of 2-methylhippurate, and orotic acid elevation reveals ammonia challenge that exceeds the capacity of the urea cycle. General hepatic detoxification stimulation by natural compounds, drugs, or xenobiotic compounds causes elevated levels of glucaric acid. Abnormalities of alpha-hydroxybutyrate, pyroglutamate, and sulfate can indicate up-regulated glut...
Source: Alternative Medicine Review - September 1, 2008 Category: Complementary Medicine Authors: Lord RS, Bralley JA Tags: Altern Med Rev Source Type: journals

The methylation, neurotransmitter, and antioxidant connections between folate and depression.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Depression is common - one-fourth of the U.S. population will have a depressive episode sometime in life. Folate deficiency is also relatively common in depressed people, with approximately one-third of depressed individuals having an outright deficiency. Folate is a water-soluble B-vitamin necessary for the proper biosynthesis of the monoamine neurotransmitters serotonin, epinephrine, and dopamine. The active metabolite of folate, 5-methyltetrahydrofolate (5-MTHF, L-methylfolate), participates in re-methylation of the amino acid metabolite homocysteine, creating methionine. S-adenosylmethionine (SAMe), the downstream ...
Source: Alternative Medicine Review - September 1, 2008 Category: Complementary Medicine Authors: Miller AL Tags: Altern Med Rev Source Type: journals

Natural approaches to revention and treatment of infections of the lower urinary tract.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Infections of the lower urinary tract are common occurrences in young women, during pregnancy, and in peri- and postmenopausal women. Because of the chronic nature of urinary tract infections (UTIs) and the potential for antibiotic resistance, a natural approach to prevention and treatment is desirable. Clinical research suggests the best natural options for long-term prevention include cranberry, mannose, and probiotics. Botanicals that can be effective at the first sign of an infection and for short-term prophylaxis include berberine and uva ursi. Estriol cream and vitamins A and C have also been shown to prevent UTI...
Source: Alternative Medicine Review - September 1, 2008 Category: Complementary Medicine Authors: Head KA Tags: Altern Med Rev Source Type: journals

Phosphatidylserine - monograph.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Authors: Phosphatidylserine (PS), a ubiquitous, endogenously occurring phospholipid, is the major acidic phospholipid in the brain. PS and other phospholipids make up the basic structural components of the cell membrane. These membrane phospholipids play an important role in cell-to-cell communication and transfer of biochemical messages into the cell, which trigger cellular responses. The proper functioning of these processes is of ultimate importance, especially in the central nervous system. It is theorized that PS enhances cellular metabolism and communication by influencing the fluidity of cell membranes. Oral su...
Source: Alternative Medicine Review - September 1, 2008 Category: Complementary Medicine Tags: Altern Med Rev Source Type: journals

Harpagophytum procumbens (Devil's Claw) -Monograph.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Authors: Historically, Harpagophytum procumbens (devil's claw) has been used as an analgesic, a remedy for fevers and allergies, and as a bitter by San bushmen in Africa to stimulate gastric enzymes and digestion. The British Herbal Pharmacopoeia recommends devil's claw as a diuretic and sedative, and the German Commission E, the German counterpart to the U.S. Food and Drug Administration, approves devil's claw for dyspepsia, appetite stimulation, and degenerative disorders of the musculoskeletal system. Devil's claw has also been used for liver and kidney disorders, as a purgative, an oxytocic, and as a topical agent...
Source: Alternative Medicine Review - September 1, 2008 Category: Complementary Medicine Tags: Altern Med Rev Source Type: journals

Alzheimer's disease, amnestic mild cognitive impairment, and age-associated memory impairment: current understanding and progress toward integrative prevention.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Alzheimer's disease, AD, is the most common form of dementia. AD initially targets memory and progressively destroys the mind. The brain atrophies as the neocortex suffers neuronal, synaptic, and dendritic losses, and the hallmark amyloid plaques and neurofibrillary tangles proliferate. Pharmacological management, at best, is palliative and transiently effective, with marked adverse effects. Certain nutrients intrinsic to human biochemistry (orthomolecules) match or exceed pharmacological drug benefits in double-blind, randomized, controlled trials, with superior safety. Early intervention is feasible because its herit...
Source: Alternative Medicine Review - June 1, 2008 Category: Complementary Medicine Authors: Kidd PM Tags: Altern Med Rev Source Type: journals

Vitamin D. Monograph.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Authors: PMID: 18590351 [PubMed - in process] (Source: Alternative Medicine Review)
Source: Alternative Medicine Review - June 1, 2008 Category: Complementary Medicine Tags: Altern Med Rev Source Type: journals

Boswellia serrata. Monograph.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Authors: PMID: 18590352 [PubMed - in process] (Source: Alternative Medicine Review)
Source: Alternative Medicine Review - June 1, 2008 Category: Complementary Medicine Tags: Altern Med Rev Source Type: journals

Alzheimers disease, amnestic mild cognitive impairment, and age-associated memory impairment: current understanding and progress toward integrative prevention.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Alzheimer's disease, AD, is the most common form of dementia. AD initially targets memory and progressively destroys the mind. The brain atrophies as the neocortex suffers neuronal, synaptic, and dendritic losses, and the hallmark amyloid plaques and neurofibrillary tangles proliferate. Pharmacological management, at best, is palliative and transiently effective, with marked adverse effects. Certain nutrients intrinsic to human biochemistry (orthomolecules) match or exceed pharmacological drug benefits in double-blind, randomized, controlled trials, with superior safety. Early intervention is feasible because its herit...
Source: Alternative Medicine Review - June 1, 2008 Category: Complementary Medicine Authors: Kidd PM Tags: Altern Med Rev Source Type: journals

Iodine: deficiency and therapeutic considerations.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Iodine deficiency is generally recognized as the most commonly preventable cause of mental retardation and the most common cause of endocrinopathy (goiter and primary hypothyroidism). Iodine deficiency becomes particularly critical in pregnancy due to the consequences for neurological damage during fetal development as well as during lactation. The safety of therapeutic doses of iodine above the established safe upper limit of 1 mg is evident in the lack of toxicity in the Japanese population that consumes 25 times the median intake of iodine consumption in the United States. Japan's population suffers no demonstrable ...
Source: Alternative Medicine Review - June 1, 2008 Category: Complementary Medicine Authors: Patrick L Tags: Altern Med Rev Source Type: journals

Therapeutic applications of pomegranate (Punica granatum L.): A Review.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The pomegranate, Punica granatum L., is an ancient, mystical, unique fruit borne on a small, long-living tree cultivated throughout the Mediterranean region, as far north as the Himalayas, in Southeast Asia, and in California and Arizona in the United States. In addition to its ancient historical uses, pomegranate is used in several systems of medicine for a variety of ailments. The synergistic action of the pomegranate constituents appears to be superior to that of single constituents. In the past decade, numerous studies on the antioxidant, anticarcinogenic, and anti-inflammatory properties of pomegranate constituent...
Source: Alternative Medicine Review - June 1, 2008 Category: Complementary Medicine Authors: Jurenka JS Tags: Altern Med Rev Source Type: journals

A double-blind, placebo-controlled, randomized trial of XP-828l (800 mg) on the quality of life and clinical symptoms of patients with mild-to-moderate psoriasis.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In a placebo-controlled clinical trial, the dietary supplement XP-828L (commercialized as Dermylex) demonstrated potential to reduce symptoms associated with mild-to-moderate psoriasis at a dose regimen of 5 g daily for 56 days. However, recent in vivo data in humans and animals suggest a daily dose of 800 mg could be more efficient than a 5-g dose. However, no well-structured clinical study has confirmed this hypothesis. The goal of the present study is to examine the effect of XP-828L at a daily dose of 800 mg on the quality of life and disease severity in patients with mild-to-moderate psoriasis. XP-828L at 800 mg p...
Source: Alternative Medicine Review - June 1, 2008 Category: Complementary Medicine Authors: Drouin R, Moroni O, Cantin K, Juneau C Tags: Altern Med Rev Source Type: journals