Alzheimer's / Dementia News From Medical News Today
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Alzheimer's Society Comment On Andrew Lansley's Speech About Charging For Care
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People over 65 could benefit from a 'home protection scheme' preventing them from being forced to sell their house to pay for residential care in old age according to the Shadow Health Secretary. Andrew Lansley highlighted the Conservative's plans to reform the care system in a speech at the National Children and Adults Services Conference yesterday (Thursday, 22 October 2009).
Source: Alzheimer's / Dementia News From Medical News Today - October 23, 2009 Category: Geriatrics Tags: Alzheimer's / Dementia Source Type: news
Protein Engineering Advancing Alzheimer's ResearchEmail this article to a colleague.
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No one has yet found a cure or a way to prevent people from developing Alzheimer's disease. Researchers from the Swedish University of Agricultural Sciences, among others, are breaking new ground in biotechnology to find new tools that can help provide new solutions. A protein constructed by these researchers has yielded experimental results that are promising when it comes to stopping the disease.
Source: Alzheimer's / Dementia News From Medical News Today - October 21, 2009 Category: Geriatrics Tags: Alzheimer's / Dementia Source Type: news
News From The American Journal Of Pathology, November 2009Email this article to a colleague.
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A group led by Dr. Dieter Brömme at the University of British Columbia has demonstrated that glycosaminoglycans (GAGs) contribute to skeletal abnormalities in patients with lysosomal storage diseases. Their report can be found in the November 2009 issue of The American Journal of Pathology. Mucopolysaccharidoses (MPS) are a group of diseases in which the dysfunction of a lysosomal enzyme results in decreased breakdown of GAGs, a type of carbohydrate, in various tissues.
Source: Alzheimer's / Dementia News From Medical News Today - October 21, 2009 Category: Geriatrics Tags: Bones / Orthopaedics Source Type: news
Health Policy Research RoundupEmail this article to a colleague.
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Urban Institute: Variation in Insurance Coverage Across Congressional Districts New Estimates from 2008 -- Drawing from data from the American Community Survey, the authors of this brief explore the variation in rates of uninsurance, public and private coverage across congressional districts.
Source: Alzheimer's / Dementia News From Medical News Today - October 12, 2009 Category: Geriatrics Tags: Health Insurance / Medical Insurance Source Type: news
Alzheimer's Society Comment On The Trial Of Personal Health Budgets, UKEmail this article to a colleague.
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Twenty sites across England have been selected to participate in a study to identify the benefits of Personal Budgets for health and patient groups who will gain most from them. The budgets are intended to give patients the freedom to choose the services they want for themselves or a family member. 'Any move to give people with dementia more control over their healthcare is a positive step.
Source: Alzheimer's / Dementia News From Medical News Today - October 9, 2009 Category: Geriatrics Tags: Alzheimer's / Dementia Source Type: news
Alzheimer's Society Comment On Research Linking High Blood Pressure To Memory ProblemsEmail this article to a colleague.
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Data in a recent study published in Neurology, the medical journal of the American Academy of Neurology links elevated diastolic blood pressure to the cognitive impairment of people over 45 The study of nearly 20,000 people aged 45 (average age 65) found that people with high diastolic blood pressure, the bottom number of a blood pressure reading, were more likely to have cognitive impairment or problems with their memory than people with normal readings.
Source: Alzheimer's / Dementia News From Medical News Today - August 27, 2009 Category: Geriatrics Tags: Hypertension Source Type: news
High Blood Pressure Linked to Cognitive ImpairmentEmail this article to a colleague.
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US researchers examining nearly 20,000 people aged 45 and over found that those with high diastolic blood pressure were more likely to have cognitive impairment, where thinking and memory ability is reduced, than people with normal diastolic pressure. The study was the work of first author Dr Georgios Tsivgoulis, of the University of Alabama at Birmingham, and colleagues, and is published in the 25 August print issue of Neurology.
Source: Alzheimer's / Dementia News From Medical News Today - August 26, 2009 Category: Geriatrics Tags: Hypertension Source Type: news
Neural Networks Mapped In Dementia PatientsEmail this article to a colleague.
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Different types of dementia show dissimilar changes in brain activity. A network mapping technique described in the open access journal BMC Neuroscience has been applied to EEG data obtained from patients with Alzheimer's disease (AD) and frontotemporal lobar degeneration (FTLD, a less common type of dementia with more prominent behavioral symptoms).
Source: Alzheimer's / Dementia News From Medical News Today - August 22, 2009 Category: Geriatrics Tags: Alzheimer's / Dementia Source Type: news
Viability Of Bone Marrow Stem Cells With Unique MRI Tracking Methods Shown By TAU ResearcherEmail this article to a colleague.
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There is no known cure for neurodegenerative diseases such as Huntington's, Alzheimer's and Parkinson's. But new hope, in the form of stem cells created from the patient's own bone marrow, can be found - and literally seen - in laboratories at Tel Aviv University. Dr. Yoram Cohen of TAU's School of Chemistry has recently proven the viability of these innovative stem cells, called mesenchymal stem cells, using in-vivo MRI. Dr.
Source: Alzheimer's / Dementia News From Medical News Today - August 21, 2009 Category: Geriatrics Tags: Stem Cell Research Source Type: news
How To Boost Value Of Alzheimer's-Fighting CompoundsEmail this article to a colleague.
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The polyphenols found in red wine are thought to help prevent Alzheimer's disease, and new research from Purdue University and Mount Sinai School of Medicine has shown that some of those compounds in fact reach the brain.
Source: Alzheimer's / Dementia News From Medical News Today - August 19, 2009 Category: Geriatrics Tags: Alzheimer's / Dementia Source Type: news
Neurimmune Therapeutics Announces Advancement Of Alzheimer's Program Into Preclinical DevelopmentEmail this article to a colleague.
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Neurimmune Therapeutics AG announced that, following the successful completion of key research milestones, its lead human therapeutic antibody for Alzheimer's disease has advanced into preclinical development, triggering milestone payments of an undisclosed amount from Biogen Idec (NASDAQ: BIIB). Neurimmune partnered with Biogen Idec for the worldwide development and commercialization of novel, fully human antibodies for the treatment of Alzheimer's disease in November 2007.
Source: Alzheimer's / Dementia News From Medical News Today - August 19, 2009 Category: Geriatrics Tags: Alzheimer's / Dementia Source Type: news
Admiral Nurses - Still Waiting For The Promised DH Urgent Review Of Anti-Psychotics 'The Drug Of Last Resort' For People With Dementia, UKEmail this article to a colleague.
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The charity for dementia and Admiral Nurses strongly supported the call for a change in practice when, in June 2008, the Department of Health (DH) announced it was to undertake an urgent review of the prescribing of anti-psychotic drugs for people with dementia. The DH stated that the review would assess the scale of inappropriate prescribing, and the reasons behind misuse of this type of medication.
Source: Alzheimer's / Dementia News From Medical News Today - August 16, 2009 Category: Geriatrics Tags: Alzheimer's / Dementia Source Type: news
UH Awarded Lead Role By EPA To Study Toxin Effects On Embryonic DevelopmentEmail this article to a colleague.
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Most people would agree that arsenic, lead, mercury, benzene and carbon monoxide pose dangers to humans. Not many, though, realize that the average person is exposed to about 10,000 different chemicals per day. Thanks to a $3.2 million grant from the Environmental Protection Agency (EPA) and its Science to Achieve Results (STAR) program, a group of University of Houston researchers is taking the lead with about $1.
Source: Alzheimer's / Dementia News From Medical News Today - August 14, 2009 Category: Geriatrics Tags: Pregnancy / Obstetrics Source Type: news
Recruitment Of New Neurons Slows When Old Brain Cells Kept From DyingEmail this article to a colleague.
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Like clockwork, brain regions in many songbird species expand and shrink seasonally in response to hormones. Now, for the first time, University of Washington neurobiologists have interrupted this natural "annual remodeling" of the brain and have shown that there is a direct link between the death of old neurons and their replacement by newly born ones in a living vertebrate.
Source: Alzheimer's / Dementia News From Medical News Today - August 12, 2009 Category: Geriatrics Tags: Neurology / Neuroscience Source Type: news
New Class Of Compounds Discovered For Potential Alzheimer's Disease DrugEmail this article to a colleague.
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A new class of molecules capable of blocking the formation of specific protein clumps that are believed to contribute to Alzheimer's disease pathology has been discovered by researchers at the University of Pennsylvania School of Medicine. By assaying close to 300,000 compounds, they have identified drug-like inhibitors of AD tau protein clumping, as reported in the journal Biochemistry. Co-authors Alex Crowe, Research Specialist; Kurt R.
Source: Alzheimer's / Dementia News From Medical News Today - August 11, 2009 Category: Geriatrics Tags: Alzheimer's / Dementia Source Type: news
Neural Stem Cells Offer Potential Treatment For Alzheimer's DiseaseEmail this article to a colleague.
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UC Irvine scientists have shown for the first time that neural stem cells can rescue memory in mice with advanced Alzheimer's disease, raising hopes of a potential treatment for the leading cause of elderly dementia that afflicts 5.3 million people in the U.S. Mice genetically engineered to have Alzheimer's performed markedly better on memory tests a month after mouse neural stem cells were injected into their brains.
Source: Alzheimer's / Dementia News From Medical News Today - July 22, 2009 Category: Geriatrics Tags: Alzheimer's / Dementia Source Type: news
Promising New Treatment For Alzheimer's Suggested Based On Hebrew University ResearchEmail this article to a colleague.
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Research carried out at the Hebrew University of Jerusalem has resulted in a promising approach to help treat Alzheimer's disease in a significant proportion of the population that suffers from a particularly rapid development of this disease.
Source: Alzheimer's / Dementia News From Medical News Today - July 22, 2009 Category: Geriatrics Tags: Alzheimer's / Dementia Source Type: news
Mayo Clinic Study Continues To Refine Most Effective Methods To Predict Alzheimer's DiseaseEmail this article to a colleague.
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This study will be presented at the Alzheimer's Association International Conference on Alzheimer's Disease on July 14 in Vienna.
Source: Alzheimer's / Dementia News From Medical News Today - July 16, 2009 Category: Geriatrics Tags: Alzheimer's / Dementia Source Type: news
Memory Test And PET Scans Detect Early Signs Of Alzheimer'sEmail this article to a colleague.
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A large study of patients with mild cognitive impairment revealed that results from cognitive tests and brain scans can work as an early warning system for the subsequent development of Alzheimer's disease.
Source: Alzheimer's / Dementia News From Medical News Today - July 16, 2009 Category: Geriatrics Tags: Alzheimer's / Dementia Source Type: news
Link Between Pesticide Levels In Blood And Parkinson's DiseaseEmail this article to a colleague.
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People with Parkinson's disease have significantly higher blood levels of a particular pesticide than healthy people or those with Alzheimer's disease, researchers at UT Southwestern Medical Center have found. In a study appearing in the July issue of Archives of Neurology, researchers found the pesticide beta-HCH (hexachlorocyclohexane) in 76 percent of people with Parkinson's, compared with 40 percent of healthy controls and 30 percent of those with Alzheimer's.
Source: Alzheimer's / Dementia News From Medical News Today - July 15, 2009 Category: Geriatrics Tags: Parkinson's Disease Source Type: news
Alzheimer's Prediction And Diagnosis May Be Improved By Brain Imaging And Proteins In Spinal FluidEmail this article to a colleague.
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Changes in the brain measured with MRI and PET scans, combined with memory tests and detection of risk proteins in body fluids, may lead to earlier and more accurate diagnosis of Alzheimer's, according to new research reported at the Alzheimer's Association 2009 International Conference on Alzheimer's Disease (ICAD 2009) in Vienna.
Source: Alzheimer's / Dementia News From Medical News Today - July 15, 2009 Category: Geriatrics Tags: Alzheimer's / Dementia Source Type: news
New Internet Survey Reveals That Almost 8 Out Of 10 UK Doctors Feel Alzheimer's Disease Is UndertreatedEmail this article to a colleague.
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The IMPACT (Important Perspectives on Alzheimer's Care & Treatment) study explored the views of 1800 people - physicians (GPs and specialists),1 Alzheimer's carers,1 payors1 and the general public1 in France, Germany, Italy, Spain and the UK According to a new study presented at the 2009 Alzheimer's Association International Conference on Alzheimer's Disease (ICAD 2009), almost 8 out of 10 UK physicians (77 percent)1 consider Alzheimer's disease to be undertreated in the UK.
Source: Alzheimer's / Dementia News From Medical News Today - July 14, 2009 Category: Geriatrics Tags: Alzheimer's / Dementia Source Type: news
Mixed Results From Trials Of DHA In Alzheimer's Disease And Age-Related Cognitive Decline Emphasize The Need For Earlier Detection And InterventionEmail this article to a colleague.
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Results from two large studies using DHA, an omega 3 fatty acid, were reported at the Alzheimer's Association 2009 International Conference on Alzheimer's Disease (ICAD 2009) in Vienna. One of the trials was conducted by the Alzheimer's Disease Cooperative Study (ADCS) supported by the National Institute on Aging (NIA), and the second by Martek Biosciences Corporation (Martek), the primary company that makes algal DHA for supplementation.
Source: Alzheimer's / Dementia News From Medical News Today - July 13, 2009 Category: Geriatrics Tags: Alzheimer's / Dementia Source Type: news
Using Structural MRI May Help Accurately Diagnose Dementia Patients: Mayo Clinic StudyEmail this article to a colleague.
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A new Mayo Clinic study may help physicians differentially diagnose three common neurodegenerative disorders in the future. The study was presented at the Alzheimer's Association International Conference on Alzheimer's Disease on July 11 in Vienna.
Source: Alzheimer's / Dementia News From Medical News Today - July 13, 2009 Category: Geriatrics Tags: Alzheimer's / Dementia Source Type: news
Research Carried Out In Mice Will Contribute To The Study Of Hereditary Diseases That Lead To BlindnessEmail this article to a colleague.
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Researchers of the University of Granada (Spain) have used a technique consisting of the induction of neuronal degeneration neuronal for intense light exposure in the mouse's retina that will be helpful for the study of retinitis pigmentosa (RP), a group of hereditary diseases which lead to blindness and affect more than one million persons a year all over the world.
Source: Alzheimer's / Dementia News From Medical News Today - July 10, 2009 Category: Geriatrics Tags: Eye Health / Blindness Source Type: news
Antibodies That May Prevent DiseaseEmail this article to a colleague.
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Antibodies to a wide range of substances that can aggregate to form plaques, such as those found in Alzheimer's patients, have been identified in the blood and cerebrospinal fluid of healthy people. Levels of these antibodies decline with age and, in Alzheimer's patients, with increasing progression of the disease.
Source: Alzheimer's / Dementia News From Medical News Today - July 8, 2009 Category: Geriatrics Tags: Alzheimer's / Dementia Source Type: news
Discovery Of Neural Stem Cell Differentiation FactorEmail this article to a colleague.
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Neural stem cells represent the cellular backup of our brain. These cells are capable of self-renewal to form new stem cells or differentiate into neurons, astrocytes or oligodendrocytes. Astrocytes have supportive functions in the environment of neurons, while oligodendrocytes form the myelin layer around axons in order to accelerate neuronal signal transmission.
Source: Alzheimer's / Dementia News From Medical News Today - July 1, 2009 Category: Geriatrics Tags: Stem Cell Research Source Type: news
Alzheimer's Society Puts Best Foot Forward With DunwoodyEmail this article to a colleague.
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This Friday 26 June, Alzheimer's Society representatives and sports personality Micky Quinn will join Richard Dunwoody, in his quest to walk 1,000 miles in 1,000 hours. Turning his half-mile stretch into a 'Memory Walk Catwalk' they will be strutting their wellie-boot chic in Newmarket to raise awareness of Alzheimer's Society's annual fundraiser 'Memory Walk' and boost awareness of the Society's work in the local area.
Source: Alzheimer's / Dementia News From Medical News Today - June 29, 2009 Category: Geriatrics Tags: Alzheimer's / Dementia Source Type: news
Remembering What To Remember And What To ForgetEmail this article to a colleague.
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People in very early stages of Alzheimer's disease already have trouble focusing on what is important to remember, a UCLA psychologist and colleagues report. "One of the first telltale signs of Alzheimer's disease may be not memory problems, but failure to control attention," said Alan Castel, UCLA assistant professor of psychology and lead author of the study.
Source: Alzheimer's / Dementia News From Medical News Today - June 27, 2009 Category: Geriatrics Tags: Alzheimer's / Dementia Source Type: news
Cerebrospinal Fluid Shows Alzheimer's Disease Deterioration Much EarlierEmail this article to a colleague.
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It is possible to determine which patients run a high risk of developing Alzheimer's disease and the dementia associated with it, even in patients with minimal memory impairment. This has been shown by recent research at the Sahlgrenska Academy, University of Gothenburg, Sweden. The results have been published in the most recent issue of the prestigious medical journal Lancet Neurology. "The earlier we can catch Alzheimer's disease, the more we can do for the patient.
Source: Alzheimer's / Dementia News From Medical News Today - June 24, 2009 Category: Geriatrics Tags: Alzheimer's / Dementia Source Type: news
Alzheimer, Headache & Co.: Detecting Neurological Illnesses Better And EarlierEmail this article to a colleague.
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The rapid development of modern neuroimaging has made a decisive improvement in the diagnosis of neurological illnesses. As Professor Filippi notes: "Neuroimaging makes new diagnostic tools available with the potential to quantify the extent of CNS injury, to define the nature of the different pathological substrates of the various CNS affections and to assess the functional changes following tissue damage with the ability to limit the clinical consequences of injury.
Source: Alzheimer's / Dementia News From Medical News Today - June 23, 2009 Category: Geriatrics Tags: Neurology / Neuroscience Source Type: news
Memory Impairment Predicts Alzheimer's DiseaseEmail this article to a colleague.
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Self perceived memory impairment is an indicator of pending Alzheimer dementia but not of vascular dementia, according to results of the LADIS (Leukoaraiosis and Disability) study which explores the impact of brain white matter changes on the functioning of independent elderly individuals over a 3 year period.
Source: Alzheimer's / Dementia News From Medical News Today - June 22, 2009 Category: Geriatrics Tags: Alzheimer's / Dementia Source Type: news
Welsh Assembly Government Opens Up Debate On Dementia, WalesEmail this article to a colleague.
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New plans to improve the support and care for individuals and their families living with dementia were announced by Health Minister Edwina Hart. Statistics from Alzheimer's Society show that there are currently more than 37,000 people with dementia in Wales, and this is set to rise to almost 50,000 within 20 years. One in three people over 65 are expected to die with a form of dementia, according to the charity.
Source: Alzheimer's / Dementia News From Medical News Today - June 21, 2009 Category: Geriatrics Tags: Alzheimer's / Dementia Source Type: news
NIH Resources Grant Extended For The National Resource For AplysiaEmail this article to a colleague.
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The National Resource for Aplysia at the University of Miami's Rosenstiel School of Marine & Atmospheric Science has had its resources grant with the National Institute for Health (NIH) extended for an additional five years. The National Resource for Aplysia is the only facility in the world that cultures and raises Aplysia californica, commonly known as sea hares or sea slugs. Over the course of the next five years, the facility will receive $2.
Source: Alzheimer's / Dementia News From Medical News Today - June 19, 2009 Category: Geriatrics Tags: Neurology / Neuroscience Source Type: news
New Data Demonstrate Potential For Early Detection Of Alzheimer's Disease Using New Diagnostic Technology, Which Could Lead To Improved TreatmentEmail this article to a colleague.
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Data published in the June issue of the Journal of Alzheimer's Disease demonstrated that minimally-invasive biospectroscopy was able to identify changes in oxidative stress (OS) levels in blood plasma, which may prove to be a useful biomarker in the early detection of Alzheimer's disease. There is currently no accepted laboratory test for diagnosing Alzheimer's disease.
Source: Alzheimer's / Dementia News From Medical News Today - June 18, 2009 Category: Geriatrics Tags: Alzheimer's / Dementia Source Type: news
Another McGill/JGH Breakthrough Opens Door To Early Alzheimer's DiagnosisEmail this article to a colleague.
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A new diagnostic technique which may greatly simplify the detection of Alzheimer's disease has been discovered by researchers at McGill University and the affiliated Lady Davis Institute for Medical Research at Montreal's Jewish General Hospital (JGH). Their results were published June 8 in the Journal of Alzheimer's Disease.
Source: Alzheimer's / Dementia News From Medical News Today - June 18, 2009 Category: Geriatrics Tags: Alzheimer's / Dementia Source Type: news
Outstanding Canadians Tireless In Their Efforts To Help Those Living With DementiaEmail this article to a colleague.
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This June, the Alzheimer Society is recognizing the extraordinary efforts of four Canadians who are rising to the challenge in the fight against Alzheimer's disease and related dementias. With a growing number of Canadians looking to the Alzheimer Society for help, the Society is paying tribute to those who go above and beyond in their work to deliver excellence in the care and support of the hundreds of thousands of people touched by this illness.
Source: Alzheimer's / Dementia News From Medical News Today - June 17, 2009 Category: Geriatrics Tags: Alzheimer's / Dementia Source Type: news
Social Care Workforce Not Ready To Deliver Dementia Care - MPsEmail this article to a colleague.
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A report published revealed the social care workforce is unfit to deliver quality care for people with dementia. 'Prepared to Care' a report by the All-Party Parliamentary Group (APPG) on Dementia found large variation in the dementia skills of the social care workforce. Barriers to delivering good care included low levels of training, ineffective regulation, lack of accreditation for trainers and a limited understanding of dementia by commissioners.
Source: Alzheimer's / Dementia News From Medical News Today - June 17, 2009 Category: Geriatrics Tags: Alzheimer's / Dementia Source Type: news
Measuring Brain's Memory Centers May Help Predict Alzheimer'sEmail this article to a colleague.
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Scientists at the University of California, San Diego School of Medicine have shown that a fully automated procedure called Volumetric MRI which measures the "memory centers" of the brain and compares them to expected size is effective in predicting the progression from mild cognitive impairment (MCI) to Alzheimer's disease. The procedure can be readily used in clinics to measure brain atrophy, and may help physicians to predict decline in MCI patients.
Source: Alzheimer's / Dementia News From Medical News Today - June 17, 2009 Category: Geriatrics Tags: Alzheimer's / Dementia Source Type: news
ExonHit Announces Last Patient Out For EHT 0202 Phase IIa Study In Alzheimer'sEmail this article to a colleague.
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ExonHit Therapeutics (Paris:ALEHT) announced that clinical testing of EHT 0202, its lead therapeutic compound in Alzheimer's disease, is progressing well. Final patient dosing for the Phase IIa proof-of-concept clinical trial assessing EHT 0202 in patients with Alzheimer's disease is completed.
Source: Alzheimer's / Dementia News From Medical News Today - June 17, 2009 Category: Geriatrics Tags: Alzheimer's / Dementia Source Type: news
Elan And Transition Therapeutics Receive Key Patent For Alzheimer's Disease Treatment With ELND005Email this article to a colleague.
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Elan Corporation, plc (NYSE: ELN) and Transition Therapeutics Inc. (TSX: TTH, NASDAQ:TTHI) today announced the United States Patent and Trademark Office issued US patent number 7,521,481 on April 21, 2009. The patent is entitled "Methods of Preventing, Treating and Diagnosing Disorders of Protein Aggregation," and generally claims methods for treating Alzheimer's disease comprising administering scyllo-inositol (ELND005).
Source: Alzheimer's / Dementia News From Medical News Today - April 24, 2009 Category: Geriatrics Tags: Alzheimer's / Dementia Source Type: news
The Pathways Of Alzheimer's That Strikes At The Young: Use Of Computational ModelEmail this article to a colleague.
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Alzheimer's disease (AD) is a tragic disease that robs an individual of their memory and mental capacity. One in eight people over the age of 65 now suffer from the disease and one in two people over 85 are diagnosed with the disease. Contrary to popular belief, Alzheimer's does not only affect the elderly. Familial Alzheimer's disease (FAD), an offshoot of the disease, affects those as young as 30.
Source: Alzheimer's / Dementia News From Medical News Today - April 17, 2009 Category: Geriatrics Tags: Alzheimer's / Dementia Source Type: news
Alzheimer's: New Findings Resolve Long Dispute About How The Disease Might Kill Brain CellsEmail this article to a colleague.
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For a decade, Alzheimer's disease researchers have been entrenched in debate about one of the mechanisms believed to be responsible for brain cell death and memory loss in the illness. Now researchers at the University of Michigan and the University of California, San Diego have settled the dispute. Resolving this controversy improves understanding of the disease and could one day lead to better treatments.
Source: Alzheimer's / Dementia News From Medical News Today - April 16, 2009 Category: Geriatrics Tags: Alzheimer's / Dementia Source Type: news
Pfizer And Medivation Initiate Phase 3 Trial Of Dimebon Added To Donepezil In Patients With Alzheimer's DiseaseEmail this article to a colleague.
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Pfizer (NYSE: PFE) and Medivation, Inc. (Nasdaq: MDVN) announced the initiation of a 12-month, Phase 3 clinical trial of the investigational drug Dimebon. The study, known as CONCERT, is designed to evaluate the safety and efficacy of Dimebon when added to ongoing treatment with donepezil HCI tablets, the leading Alzheimer's disease (AD) medication worldwide, in patients with mild-to-moderate AD.
Source: Alzheimer's / Dementia News From Medical News Today - April 16, 2009 Category: Geriatrics Tags: Alzheimer's / Dementia Source Type: news
Alzheimer Cell Death In Zebrafish: Demise Of Neurons Observed Live For The First TimeEmail this article to a colleague.
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Extensive death of nerve cells leads to severe dementia in patients with Alzheimer's disease. Until now, it has only been possible to investigate the neuronal devastation in post mortem animal models, and by using complicated methods. Researchers at the German Center for Neurodegenerative Disease at LMU Munich, headed by Professor Christian Haass, have now successfully observed this demise of nerve cells by life imaging.
Source: Alzheimer's / Dementia News From Medical News Today - April 15, 2009 Category: Geriatrics Tags: Alzheimer's / Dementia Source Type: news
Best Practices Identified For Early Alzheimer's DetectionEmail this article to a colleague.
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Diagnosing mild-to-moderate dementia cases can be difficult. Indeed, more than half of such cases are not recognized by physicians, according to a recent review of the literature at the Medical College of Wisconsin in Milwaukee. In fact, family members and caregivers, in addition to many physicians, often overlook a decline in cognitive function as well. To improve prompt diagnosis, Diana Kerwin, M.D.
Source: Alzheimer's / Dementia News From Medical News Today - April 3, 2009 Category: Geriatrics Tags: Alzheimer's / Dementia Source Type: news
Effects Of Disease Severity On Autobiographical Memory In Semantic Dementia Revealed In New StudyEmail this article to a colleague.
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In a study conducted by the Laboratory of Neuropsychology of the Université de Caen Basse-Normandie and published by Elsevier in the April 2009 issue of Cortex (http://www.elsevier.com/locate/cortex), researchers studied for the first time autobiographical memory in a group of semantic dementia (SD) patients according to disease progression.
Source: Alzheimer's / Dementia News From Medical News Today - April 3, 2009 Category: Geriatrics Tags: Alzheimer's / Dementia Source Type: news
Elan And Wyeth Plan To Amend Bapineuzumab Phase 3 ProtocolsEmail this article to a colleague.
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Elan Corporation, plc (NYSE: ELN) and Wyeth (NYSE: WYE) announced that the companies will discontinue the highest of three dosing regimens, 2.0 mg/kg, in the two ongoing Phase 3 studies of bapineuzumab in patients with mild to moderate Alzheimer's disease (AD) who do not carry the Apolipoprotein E4 (ApoE4) allele (non-carriers). ApoE4 is a known genetic risk factor for development of AD. The 0.5 mg/kg and 1.0 mg/kg doses in these two trials will continue as planned.
Source: Alzheimer's / Dementia News From Medical News Today - April 3, 2009 Category: Geriatrics Tags: Alzheimer's / Dementia Source Type: news
Alzheimer's Disease Linked To Mitochondrial DamageEmail this article to a colleague.
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Investigators at the Burnham Institute for Medical Research (Burnham) have demonstrated that attacks on the mitochondrial protein Drp1 by the free radical nitric oxide which causes a chemical reaction called S-nitrosylation mediates neurodegeneration associated with Alzheimer's disease. Prior to this study, the mechanism by which beta-amyloid protein caused synaptic damage to neurons in Alzheimer's disease was unknown.
Source: Alzheimer's / Dementia News From Medical News Today - April 3, 2009 Category: Geriatrics Tags: Alzheimer's / Dementia Source Type: news
Alzheimer's Society Comment On Deprivation Of Liberty Safeguards, UKEmail this article to a colleague.
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Deprivation of liberty safeguards have been introduced into the Mental Capacity Act in order to prevent arbitrary decisions that deprive people of their liberty. The safeguards cover people in hospital and care homes registered under the Care Standards Act 2000. They have been designed to deter deprivation of liberty and, where it is unavoidable, ensure cases are reviewed, monitored and can be appealed. The safeguards are now a statutory obligation (from April 2009 onwards).
Source: Alzheimer's / Dementia News From Medical News Today - April 2, 2009 Category: Geriatrics Tags: Alzheimer's / Dementia Source Type: news
