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Gut Microbiome Changes in Patients With Idiopathic Normal Pressure Hydrocephalus
CONCLUSIONS: Here we report the first identified microbiome differences in iNPH patients compared with healthy controls.PMID:38602449 | DOI:10.1097/WAD.0000000000000613 (Source: Alzheimer Disease and Associated Disorders)
Source: Alzheimer Disease and Associated Disorders - April 11, 2024 Category: Psychiatry Authors: Emilia Brandt Anne Koivisto Pedro Pereira Ella Mustanoja Petri Auvinen Toni Saari Juha-Matti Lehtola Sanna Hannonen Minna Rusanen Ville Leinonen Filip Scheperjans Virve K ärkkäinen Source Type: research

Feasibility and Acceptability of a Multifaceted Observational Protocol to Investigate Lucidity in Advanced Dementia
DISCUSSION: Longitudinal video observation among individuals with advanced dementia in hospice care for the detection of lucidity was feasible and highly acceptable. Multidimensional, temporal coding of features of ELs is feasible but time-intensive.PMID:38587070 | DOI:10.1097/WAD.0000000000000615 (Source: Alzheimer Disease and Associated Disorders)
Source: Alzheimer Disease and Associated Disorders - April 8, 2024 Category: Psychiatry Authors: Alison Coulson Clark Benson Jess Fehland Kayla Dillon Kimberly Mueller Andrea Gilmore-Bykovskyi Source Type: research

Comparison of Enlarged Perivascular Spaces in Early-Onset and Late-Onset Alzheimer Disease-related Cognitive Impairment: A Single Clinic-based Study in South Korea
We examined whether there were differences in the presence of centrum semiovale-enlarged perivascular spaces (CSO-ePVS) and basal ganglia-ePVS (BG-ePVS) among patients with Alzheimer disease-related cognitive impairment (ADCI) based on their age of onset. Out of a total of 239 patients with cognitive impairment, 155 with positive amyloid-PET results were included. Among these, 43 had early-onset ADCI (EOADCI) and 112 had late-onset ADCI (LOADCI). Patients with LOADCI exhibited a higher prevalence of hypertension, lacunes, white matter hyperintensities, and BG-ePVS than those with EOADCI. BG-ePVS showed a significant correl...
Source: Alzheimer Disease and Associated Disorders - April 2, 2024 Category: Psychiatry Authors: Na-Yeon Jung Yuri Je Hong-Gi Ham Yu Hyun Park Tae-Yun Kim Min-Su Go Hye-In Lee Da Eun Kim Myung Jun Lee Sang Won Seo Eun-Joo Kim Source Type: research

The Association Between Physical Activity and Cognition in a Racially/Ethnically Diverse Cohort of Older Adults: Results From the Kaiser Healthy Aging and Diverse Life Experiences Study
CONCLUSION: PA is associated with cognition in this racially/ethnically diverse sample and may have larger benefits for individuals with low cognitive scores, who are most vulnerable to dementia.PMID:38533734 | DOI:10.1097/WAD.0000000000000612 (Source: Alzheimer Disease and Associated Disorders)
Source: Alzheimer Disease and Associated Disorders - March 27, 2024 Category: Psychiatry Authors: Mariana L Almeida Anna M Pederson Scott C Zimmerman Ruijia Chen Sarah Ackley Alicia Riley Chloe W Eng Rachel A Whitmer Kristen M George Rachel L Peterson Elizabeth Rose Mayeda Paola Gilsanz Dan M Mungas Sarah Tomaszewski Farias M Maria Glymour Source Type: research