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AMBIEN CR (Zolpidem Tartrate) Tablet, Coated [Sanofi-Aventis U.S. LLC]email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Updated Date: Nov 20, 2009 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))
Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) - November 20, 2009 Category: Drugs & Pharmacology Source Type: organizations

Determination of 19 drugs of abuse and metabolites in whole blood by high-performance liquid chromatography-tandem mass spectrometry.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
A high-performance liquid chromatography (LC)-tandem mass spectrometry (MS/MS) method has been developed and validated for the determination of 19 drugs of abuse and metabolites and used in whole blood. The following compounds were included: amphetamine, methylenedioxyamphetamine, methylenedioxyethylamphetamine, methylenedioxymethamphetamine, methamphetamine, cocaine, benzoylecgonine, morphine, 6-acetylmorphine, codeine, methadone, buprenorphine, norbuprenorphine, ketobemidone, tramadol, O-desmethyltramadol, zaleplone, zolpidem, and zopiclone. The sample pretreatment consisted of solid-phase extraction using mixed-mode...
Source: Analytical and Bioanalytical Chemistry - November 18, 2009 Category: Chemistry Authors: Bjørk MK, Nielsen MK, Markussen LO, Klinke HB, Linnet K Tags: Anal Bioanal Chem Source Type: journals

ZOLPIDEM TARTRATE (Zolpidem) Tablet, Coated [Physicians Total Care, Inc.]email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Updated Date: Nov 13, 2009 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))
Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) - November 13, 2009 Category: Drugs & Pharmacology Source Type: organizations

Zolpidem: Sleepwalking in an elderly patient: case reportemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
(Source: Reactions)
Source: Reactions - November 11, 2009 Category: Drugs & Pharmacology Tags: Short communication Source Type: journals

Hopes for new brain-damage drugemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
SPECT trial reportedly shows that zolpidem drug counteracts loss of cognitive and motor functions associated with brain damage (Source: Pharmacy Europe)
Source: Pharmacy Europe - November 10, 2009 Category: Drugs & Pharmacology Source Type: news

ZOLPIDEM TARTRATEtablet, Film Coated [Roxane Laboratories, Inc]email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Updated Date: Nov 9, 2009 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))
Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) - November 9, 2009 Category: Drugs & Pharmacology Source Type: organizations

ZOLPIDEM TARTRATEtablet [American Health Packaging]email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Updated Date: Nov 4, 2009 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))
Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) - November 4, 2009 Category: Drugs & Pharmacology Source Type: organizations

Transcept Pharmaceuticals Receives Complete Response Letter from FDA on Intermezzo New Drug Applicationemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
RICHMOND, Calif., Oct. 29 /PRNewswire-FirstCall/ -- Transcept Pharmaceuticals announced today that the U.S. Food and Drug Administration (FDA) issued a Complete Response Letter regarding the New Drug Application (NDA) for Intermezzo (zolpidem... (Source: Drugs.com - New Drug Applications)
Source: Drugs.com - New Drug Applications - October 30, 2009 Category: Drugs & Pharmacology Source Type: news

Transcept Pharmaceuticals Receives Complete Response Letter From FDA On Intermezzo(R) New Drug Applicationemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Transcept Pharmaceuticals (Nasdaq: TSPT) announced that the U.S. Food and Drug Administration (FDA) issued a Complete Response Letter regarding the New Drug Application (NDA) for Intermezzo® (zolpidem tartrate sublingual tablet). The NDA, submitted by Transcept in September 2008, seeks approval to market Intermezzo® for use as-needed for the treatment of insomnia when a middle of the night awakening is followed by difficulty returning to sleep. (Source: Pharma Industry News From Medical News Today)
Source: Pharma Industry News From Medical News Today - October 30, 2009 Category: Pharmaceuticals Tags: Sleep / Sleep Disorders / Insomnia Source Type: news

Transcept Pharmaceuticals Receives Complete Response Letter from FDA on Intermezzo(R) New Drug Applicationemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conference Call Scheduled for 8:30 a.m. EDT on October 29, 2009 RICHMOND, Calif., Oct. 29 (HSMN NewsFeed) -- Transcept Pharmaceuticals (Nasdaq: TSPT ) announced today that the U.S. Food and Drug Administration (FDA) issued a Complete Response Letter r... Biopharmaceuticals, FDATranscept Pharmaceuticals, Intermezzo, zolpidem, insomnia (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - October 29, 2009 Category: Pharmaceuticals Source Type: news

Transcept Pharmaceuticals Receives Complete Response Letter From FDA On Intermezzo® New Drug Applicationemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Transcept Pharmaceuticals (Nasdaq: TSPT) announced today that the U.S. Food and Drug Administration (FDA) issued a Complete Response Letter regarding the New Drug Application (NDA) for Intermezzo® (zolpidem tartrate sublingual tablet). (Source: Pharmaceutical Online News)
Source: Pharmaceutical Online News - October 29, 2009 Category: Pharmaceuticals Source Type: news

Caring for the Elderly in an Inpatient Setting: Managing Insomnia and Polypharmacyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
This article addresses these concerns by highlighting key points from the available literature. Insomnia may be a problem in the elderly because of their increased sensitivity to changes in environment among other factors. First, obtain a sleep history and a comprehensive medical and medication history to identify the cause. Next, treat the underlying cause with nonpharmacological interventions to restore restful and qualitative sleep. When nonpharmacological interventions are not successful, pharmacological means are indicated. Remember to start low, go slow, and treat for a short duration of time (less than 4 weeks) to a...
Source: Journal of Pharmacy Practice - October 21, 2009 Category: Drugs & Pharmacology Authors: Kim, J., Tofade, T. S., Peckman, H. Tags: Continuing Education Article Source Type: journals

Discriminative stimulus effects of L-838,417 (7-tert-Butyl-3-(2,5-difluoro-phenyl)-6-(2-methyl-2H-[1,2,4]triazol-3-ylmethoxy)-[1,2,4]triazolo[4,3-b]pyridazine): Role of GABA(A) receptor subtypes.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Previous reports suggest that gamma-aminobutyric acid type A (GABA(A)) receptors containing alpha1 subunits may play a pivotal role in mediating the discriminative stimulus effects of benzodiazepines (BZs). L-838,417 (7-tert-Butyl-3-(2,5-difluoro-phenyl)-6-(2-methyl-2H-[1,2,4]triazol-3-ylmethoxy)-[1,2,4]triazolo[4,3-b]pyridazine) is a GABA(A) receptor modulator with intrinsic efficacy in vitro at alpha2, alpha3, and alpha5 subunit-containing GABA(A) receptors, and little demonstrable intrinsic efficacy in vitro at alpha1 subunit-containing GABA(A) receptors. The present study evaluated the discriminative stimulus effec...
Source: Neuropharmacology - October 21, 2009 Category: Drugs & Pharmacology Authors: Licata SC, Platt DM, Rüedi-Bettschen D, Atack JR, Dawson GR, Van Linn ML, Cook JM, Rowlett JK Tags: Neuropharmacology Source Type: journals

ZOLPIDEM TARTRATE (Zolpidem) Tablet, Coated [Physicians Total Care, Inc.]email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Updated Date: Oct 20, 2009 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))
Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) - October 20, 2009 Category: Drugs & Pharmacology Source Type: organizations

Zolpidem-Induced Sleepwalking, Sleep Related Eating Disorder, and Sleep-Driving: Fluorine-18-Flourodeoxyglucose Positron Emission Tomography Analysis, and a Literature Review of Other Unexpected Clinical Effects of Zolpidememail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
We report the results and a review of the literature regarding other unintended effects seen with zolpidem use. Keywords: Zolpidem, fluorine-18-flourodeoxyglucose positron emission tomography, sleep related eating disorder, sleepwalking, sleep-driving (Source: Journal of Clinical Sleep Medicine : JCSM)
Source: Journal of Clinical Sleep Medicine : JCSM - October 15, 2009 Category: Sleep Medicine Source Type: journals

AMBIEN CR (Zolpidem Tartrate) Tablet, Coated [Sanofi-Aventis U.S. LLC]email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Updated Date: Oct 14, 2009 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))
Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) - October 14, 2009 Category: Drugs & Pharmacology Source Type: organizations

AMBIEN (Zolpidem Tartrate) Tablet, Film Coated [Sanofi-Aventis U.S. LLC]email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Updated Date: Oct 14, 2009 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))
Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) - October 14, 2009 Category: Drugs & Pharmacology Source Type: organizations

Residual effects of hypnotic drugs in aging drivers submitted to simulated accident scenarios: an exploratory studyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions  This study did not reveal any major residual effects of the hypnotics studied on driving performance in aging drivers. However, the urban driving situations used here for the first time in the evaluation of drugs revealed some modifications in driving habits which could lead to risky behavior. It thus appears that urban driving simulations are useful for gaining knowledge about the effects of drugs on driving behavior. Content Type Journal ArticleCategory Original InvestigationDOI 10.1007/s00213-009-1677-2Authors Mohamed Meskali, INRETS (French National Institute for Transport and Safety ...
Source: Psychopharmacology - October 1, 2009 Category: Psychiatry Tags: Psychopharmacology Source Type: journals

Sleep Aid Suppresses Reflux-Related Awakeningemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Zolpidem, a frequently prescribed sleep aid, suppresses nocturnal awakenings that are an important CNS response to acid reflux events. By enabling users to sleep through reflux events, the drug has the unintended effect of increasing esophageal exposure to stomach acid. This in turn opens the door to gastroesophageal reflux disease (GERD) complications such as erosive esophagitis, stricture formation, Barrett's esophagus, and esophageal adenocarcinoma, said Dr. Gregg Gagliardi of Thomas Jefferson University, Philadelphia, and his associates. (Source: Clinical Psychiatry News)
Source: Clinical Psychiatry News - September 30, 2009 Category: Psychiatry Authors: MARY ANN MOON Tags: Psychosomatic Medicine Source Type: journals

Lipitor, Seroquel and Ambien CR Web Sites Rank Highest for Ease of Use, Content Qualityemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Report Assesses Degree to Which Pharma Sites Connect With Consumers Online (PRWeb Sep 23, 2009) Read the full story at http://www.prweb.com/releases/2009/09/prweb2919554.htm (Source: PRWeb: Medical Pharmaceuticals)
Source: PRWeb: Medical Pharmaceuticals - September 23, 2009 Category: Pharmaceuticals Source Type: news

Sleep Aid May Lead to More Acid Reflux Exposureemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
The sleep-inducing drug zolpidem may help patients with gastroesophageal reflux sleep through reflux events, increasing their acid exposure, according to research published in the September issue of Clinical Gastroenterology and Hepatology. (Source: Modern Medicine)
Source: Modern Medicine - September 17, 2009 Category: Journals (General) Source Type: info

Zolpidem increases bladder capacity and decreases urine excretion in ratsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
To clarify the effects of zolpidem, a [gamma]-aminobutyric acid (GABA)A receptor agonist, on bladder function, and urine production, we investigated the effects of zolpidem administration on bladder overactivity induced by cerebral infarction (CI) and on urine excretion increased by water overloading in Wistar rats.CI was induced by left middle cerebral artery occlusion. The effects on bladder function of zolpidem alone or in combination with the GABAA receptor antagonist bicuculline, were then examined in the CI rats using cystometry. The antidiuretic effect of zolpidem was investigated in water-loaded and Brattleboro rat...
Source: Neurourology and Urodynamics - September 15, 2009 Category: Urology & Nephrology Authors: Osamu Yokoyama, Yosuke Matsuta, Hiroko Yanai-Inamura, Mai Watanabe, Akiyoshi Ohtake, Masanori Suzuki, Masao Sasamata Source Type: journals

Synthetic and Natural Compounds that Interact with Human Cytochrome P450 1A2 and Implications in Drug Development.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Human cytochrome P450 1A2 (CYP1A2) is one of the major CYPs in the liver ( approximately 13%) and metabolizes about 20% of clinically used drugs. CYP1A2 is a 515-residue protein with a molecular mass of 58,294 Dal. The recently published crystal structure of CYP1A2 in complex with alpha-naphthoflavone has showed a rather compact active site with a relatively small volume of the cavity of 375 A(3), which is 44.2% and 49.3% larger than that of CYP2A6 (260 A(3)) and CYP2E1 (190 A(3)), respectively. A series of residues in the substrate recognition regions of CYP1A2 (e.g. Arg108, Thr124, Thr223, Glu225, Phe226, Lys250, Arg...
Source: Current Medicinal Chemistry - September 15, 2009 Category: Chemistry Authors: Wang B, Zhou SF Tags: Curr Med Chem Source Type: journals

Excellent response to oral zolpidem in a sporadic case of the myoclonus dystonia syndromeemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
No abstract. (Source: Movement Disorders)
Source: Movement Disorders - September 3, 2009 Category: Neurology Authors: In-Seok Park, Joong-Seok Kim, Jae-Young An, Yeong-In Kim, Kwang-Soo Lee Source Type: journals

Moss Rehabilitation Research Institute Launches Largest Study To Date To Explore "Awakening" Effects Of Common Sleep Drug On Vegetative Patientsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Moss Rehabilitation Research Institute (MRRI), the research arm of MossRehab, one of the world's leading clinical rehabilitation centers, has launched an ambitious research study to investigate how the sleep drug zolpidem might restore consciousness for patients in the vegetative state. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - September 2, 2009 Category: Consumer Health News Tags: Sleep / Sleep Disorders / Insomnia Source Type: news

Zolpidem: Amnesia: case reportemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
(Source: Reactions)
Source: Reactions - August 31, 2009 Category: Drugs & Pharmacology Tags: Short communication Source Type: journals

ZOLPIDEM TARTRATEtablet, Film Coated [Qualitest Pharmaceuticals]email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Updated Date: Aug 26, 2009 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))
Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) - August 26, 2009 Category: Drugs & Pharmacology Source Type: organizations

EDLUAR (Zolpidem Tartrate) Tablet [Meda Pharmaceuticals]email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Updated Date: Aug 17, 2009 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))
Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) - August 17, 2009 Category: Drugs & Pharmacology Source Type: organizations

Meta-Analyses of Hypnotics and Infections: Eszopiclone, Ramelteon, Zaleplon, and Zolpidememail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions: Research is needed to objectively determine whether the use of hypnotics increases the risk of infections. Immune compromise or esophageal reflux and aspiration should be studied as possible mechanisms. Keywords: Eszopiclone, ramelteon, zaleplon, zolpidem, infection, inflammation, meta-analysis (Source: Journal of Clinical Sleep Medicine : JCSM)
Source: Journal of Clinical Sleep Medicine : JCSM - August 15, 2009 Category: Sleep Medicine Source Type: journals

Retrograde effects of triazolam and zolpidem on sleep-dependent motor learning in humansemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Drugs that act as allosteric activators at the benzodiazepine site of the gamma-aminobutyric acid (GABAA) receptor complex are used commonly to treat insomnia but relatively little is known of how such use affects learning and memory. Although anterograde effects on memory acquisition have been shown, possible retrograde effects on consolidation are more relevant when such agents are administered at bedtime. We tested the effects of two GABAA allosteric activators on sleep-dependent motor skill memory consolidation in 12 healthy male subjects. Subjects slept in a sleep laboratory for four consecutive nights (one accommodat...
Source: Journal of Sleep Research - August 13, 2009 Category: Neurology Authors: PETER T. MORGAN, JOHN H. KEHNE, KEN J. SPRENGER, ROBERT T. MALISON Source Type: journals

EDLUAR (Zolpidem Tartrate) Tablet [Meda Pharmaceuticals Inc.]email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Updated Date: Aug 13, 2009 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))
Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) - August 13, 2009 Category: Drugs & Pharmacology Source Type: organizations

Retrograde effects of triazolam and zolpidem on sleep-dependent motor learning in humans.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Drugs that act as allosteric activators at the benzodiazepine site of the gamma-aminobutyric acid (GABA(A)) receptor complex are used commonly to treat insomnia but relatively little is known of how such use affects learning and memory. Although anterograde effects on memory acquisition have been shown, possible retrograde effects on consolidation are more relevant when such agents are administered at bedtime. We tested the effects of two GABA(A) allosteric activators on sleep-dependent motor skill memory consolidation in 12 healthy male subjects. Subjects slept in a sleep laboratory for four consecutive nights (one ac...
Source: Journal of Sleep Research - August 12, 2009 Category: Sleep Medicine Authors: Morgan PT, Kehne JH, Sprenger KJ, Malison RT Tags: J Sleep Res Source Type: journals

Treatment of sleep dysfunction and psychiatric disordersemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Opinion statement  Patients with neurologic disorders commonly experience sleep dysfunction and psychiatric disorders. The most common sleep dysfunction is insomnia, which is a primary symptom in 30% to 90% of psychiatric disorders. Insomnia and fatigue are prominent symptoms of anxiety disorders and major depression that may occur in patients who are treated but have residual sleep dysfunction. Anxiety and depressive disorders account for 40% to 50% of all cases of chronic insomnia. It is also recognized that primary insomnia and other primary sleep disorders produce symptoms that are similar to those report...
Source: Current Treatment Options in Neurology - August 11, 2009 Category: Neurology Tags: Current Treatment Options in Neurology Source Type: journals

Treatment of nocturnal eating disordersemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Opinion statement  Identifying abnormal nocturnal eating is critically important for patient care and public health. Obesity is a global pandemic and a leading cause of preventable mortality in the United States, with more than 100,000 deaths annually. Normally, nighttime energy homeostasis is maintained, despite an absence of food intake, through appetite suppression and alterations in glucose metabolism that result in stable energy stores. Two conditions break this nighttime fast and are associated with weight gain as well as medical and neuropsychiatric comorbidities. Sleep-related eating disorder (SRED) i...
Source: Current Treatment Options in Neurology - August 11, 2009 Category: Neurology Tags: Current Treatment Options in Neurology Source Type: journals

My story...email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Author: mwflorida Posted: Mon Aug 10, 2009 4:37 am hello! Thanks for sharing your story... I too am in the health care field, just slightly different, I am in the mental health field, a family therapist. I was on suboxone for 18 days and then stopped at 1 mg. truthfully, it was a relatively mild transition. about 5-7 days of feeling off, achy, not comfortable in my own skin, but not terrible at all. Ambien helped at night, amino acids helped alot during the day... maybe this is the clinical side of me coming out to you, but whatever you do, make sure you are honest...
Source: Suboxone Forum - August 10, 2009 Category: Addiction Source Type: forums

Sleep aids may pose a risk to the elderlyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
My 88-year-old husband was prescribed Ambien for insomnia. After the first dose, he fell while getting up to go to the bathroom, gashed his head and had to go to the emergency room for stitches. A year later, I gave him a half-dose (again prescribed), and within minutes, his legs collapsed on him. I had the hardest time getting him into bed. Ambien? Never again! (Source: L.A. Times - Health)
Source: L.A. Times - Health - August 8, 2009 Category: Consumer Health News Source Type: news

Zolpidem (Ambien®) in pregnancy: placental passage and outcomeemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract  To examine the extent and clinical sequelae of fetal exposure to zolpidem, a commonly prescribed hypnotic agent. Pregnant women with psychiatric illness participating in a study of psychotropic pharmacokinetics were included. Zolpidem concentrations were analyzed in maternal and umbilical cord plasma collected at delivery. Outcomes were compared between the zolpidem-exposed group and a 1:1 matched comparator group. Forty-five women taking zolpidem during pregnancy were studied. Rates of preterm delivery and low birth weight were 26.7% and 15.6% respectively in the zolpidem-exposed group versus 13.3%...
Source: Archives of Women's Mental Health - August 5, 2009 Category: Psychiatry & Psychology Tags: Archives of Women's Mental Health Source Type: journals

Purdue Pharmaceutical Products L.P. And Transcept Pharmaceuticals, Inc. Sign Exclusive Agreement To Commercialize Intermezzo® In The United Statesemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Purdue Pharmaceutical Products L.P. and Transcept Pharmaceuticals, Inc. (Nasdaq: TSPT) today announced entry into an exclusive license and collaboration agreement to commercialize Intermezzo® (zolpidem tartrate sublingual tablet) in the United States. (Source: Pharmaceutical Online News)
Source: Pharmaceutical Online News - August 4, 2009 Category: Pharmaceuticals Source Type: news

Zolpidem: Erythroderma (first report) in an elderly patient: case reportemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
(Source: Reactions)
Source: Reactions - August 3, 2009 Category: Drugs & Pharmacology Tags: Short communication Source Type: journals

Med Sci Monit 2009; 15(8):CS129-131 "Catatonia recognition and treatment"email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions: This case seems to confirm that catatonia can represents a nonspecific response to stress factors. The withdrawal of multiple medications was already described as a basis for catatonia. Alcohol withdrawal could constitute an additional risk factor for catatonia. The zolpidem test is a useful diagnostic and therapeutic test. (Source: Medical Science Monitor)
Source: Medical Science Monitor - July 31, 2009 Category: Research Source Type: journals

Warning To Consumers About Recreational Use Of Medicines, Australiaemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
The National Prescribing Service (NPS) warns people are playing Russian roulette with their health when they take medicines inappropriately. Media reports this week about people mixing sleeping tablet, zolpidem (Stilnox), with energy drink Red Bull™ have failed to highlight the risks people are taking when they intentionally misuse pharmaceuticals. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - July 30, 2009 Category: Consumer Health News Tags: Pharmacy / Pharmacist Source Type: news

Sleep toooooo much! Helpemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Author: Calliope Posted: Tue Jul 28, 2009 2:26 am jsp4th wrote: yah sometimes I only take 1/4 of the zanaflex...they knock out the headache but they knock me out too. I keep hearing about clonidine...it's a blood pressure med right? i'm only 26 and i'm not sure if I want to go that route. I hear of a naltrexone implant that you can get after subs...thinking about that for after I get off subs. Trying to cut down to 16mg third day down 1 pill...feel ok not great but better than I thought. Sleep has been great w/out ambien. Don't know if i'm gonna take that ever...
Source: Suboxone Forum - July 28, 2009 Category: Addiction Source Type: forums

A 2-week efficacy and safety study of gaboxadol and zolpidem using electronic diaries in primary insomnia outpatientsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract: Objectives: To evaluate the efficacy and safety profile of gaboxadol, a selective extrasynaptic GABAA agonist (SEGA) previously in development for the treatment of insomnia.Methods: This was a randomised, double-blind, placebo-controlled, parallel-group, 2-week, Phase III study of gaboxadol 5, 10 and 15mg in outpatients meeting the DSM-IV criteria of primary insomnia (N=742). Zolpidem 10mg was used as active reference.Results: At weeks 1 and 2, significant improvement in total sleep time (sTST) compared to placebo was seen for all doses of gaboxadol (all p (Source: Sleep Medicine)
Source: Sleep Medicine - July 24, 2009 Category: Sleep Medicine Authors: Göran Hajak, Jan Hedner, Mirjam Eglin, Henrik Loft, Signe í Stórustovu, Simone Lütolf, Jonas Lundahl, On behalf of the Gaboxadol Study 99775 Group Tags: Original Articles Source Type: journals

The Mothers Act Disease Mongering Campaign - Part Iemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
(NaturalNews) The Mothers Act represents the ultimate example of disease mongering at its worst because the eight-year attempt to pass this federal legislation has evolved into profiteering never before exhibited so conspicuously.Disease mongering "is the selling of sickness that widens the boundaries of illness and grows the markets for those who sell and deliver treatments," according to Ray Moyniahan and David Henry in the April 11, 2006 paper in PLoS Med, titled, "The Fight against Disease Mongering." "It is exemplified most explicitly by many pharmaceutical industry -- funded disease-awareness campaigns -- more often ...
Source: NaturalNews.com - July 16, 2009 Category: Consumer Health Advice Source Type: news

Occupational airborne contact dermatitis to simvastatin, carvedilol, and zolpidememail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
(Source: Contact Dermatitis)
Source: Contact Dermatitis - July 15, 2009 Category: Dermatology Authors: Michal Neumark, Shlomo Moshe, Arieh Ingber, Dan Slodownik Tags: Contact Points Source Type: journals

Brotizolam/triazolam/zolpidem: Anxiety, psychomotor agitation and confusion: 2 case reportsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
(Source: Reactions)
Source: Reactions - July 13, 2009 Category: Drugs & Pharmacology Tags: Short communication Source Type: journals

Brotizolam/triazolam/zolpidem: Anxiety, psychomotor agitation and confusion: 2 case reports.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Page: 9 (Source: Reactions Weekly)
Source: Reactions Weekly - July 11, 2009 Category: Drugs & Pharmacology Tags: HTML Source Type: journals

ZOLPIDEM TARTRATEtablet [Mylan Pharmaceuticals Inc.]email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Updated Date: Jul 9, 2009 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))
Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) - July 9, 2009 Category: Drugs & Pharmacology Source Type: organizations

My journey to sobrietyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Author: Unsponsored Posted: Thu Jul 09, 2009 12:38 am Hello, I'm 23 years old and discovered oc , and binged for 8 months : 160mg- 320 mg OC a day. I believed that I could quit cold turkey in January but it was too hard with work and school.. So I decided to go on suboxone, which I have been taking for about 6 months. I am tapering off pretty quickly actually and it has been working out nicely. week 1 - 1.5 mg -> 1mg, gradual reduction (each pill slightly smaller than the other) week 2 - 1 mg - stabilize week 3 - 0.75 - >0.5 mg gradual reduction(each pill sl...
Source: Suboxone Forum - July 8, 2009 Category: Addiction Source Type: forums

Highway driving performance and cognitive functioning the morning after bedtime and middle-of-the-night use of gaboxadol, zopiclone and zolpidem. - Leufkens TR, Lund JS, Vermeeren A.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Gaboxadol is a selective extrasynaptic GABA(A) receptor agonist previously in development for the treatment of insomnia. Due to its short half-life (1.5-2 h) it is expected to be free from residual effects the next morning. The present study assessed the r... (Source: SafetyLit: All (Unduplicated))
Source: SafetyLit: All (Unduplicated) - July 5, 2009 Category: Global & Universal Tags: Alcohol and Other Drugs Source Type: info