Effect of residual platelets in frozen-thawed plasma on results of dilute Russell's viper venom time assay for lupus anticoagulant testing
CONCLUSIONS: Residual platelets in plasma samples result in shortening of DRVVT assay after 1 freeze-thaw cycle. This may result in a false-negative LAC test result.PMID:37878771 | DOI:10.1093/ajcp/aqad138 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - October 25, 2023 Category: Pathology Authors: Brenda J Nelson Strande Meera Sridharan Rachel R Leger Melissa S Stuart Julie I Tange Serena D Navitska Nahla Heikal Aneel A Ashrani Dong Chen Jansen N Seheult Rajiv K Pruthi Source Type: research

Acute leukemia with cytogenetically cryptic FGFR1 rearrangement and lineage switch during therapy: A case report and literature review
CONCLUSIONS: Ours is the only reported case of FGFR1-rearranged neoplasms with a disease sequence of acute myeloid leukemia transforming to B-cell acute lymphoblastic leukemia and 1 of only 3 reported cases with cytogenetically cryptic FGFR1 rearrangement. Fluorescence in situ hybridization testing for FGFR1 rearrangement should be a standard investigation in leukemia of mixed or switching lineage.PMID:37855739 | DOI:10.1093/ajcp/aqad135 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - October 19, 2023 Category: Pathology Authors: Sean J McKeague Kacey O'Rourke Stephen Fanning Christopher Joy Duncan Throp Rebecca Adams Yasmin Harvey Tee Beng Keng Source Type: research

Acute leukemia with cytogenetically cryptic FGFR1 rearrangement and lineage switch during therapy: A case report and literature review
CONCLUSIONS: Ours is the only reported case of FGFR1-rearranged neoplasms with a disease sequence of acute myeloid leukemia transforming to B-cell acute lymphoblastic leukemia and 1 of only 3 reported cases with cytogenetically cryptic FGFR1 rearrangement. Fluorescence in situ hybridization testing for FGFR1 rearrangement should be a standard investigation in leukemia of mixed or switching lineage.PMID:37855739 | DOI:10.1093/ajcp/aqad135 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - October 19, 2023 Category: Pathology Authors: Sean J McKeague Kacey O'Rourke Stephen Fanning Christopher Joy Duncan Throp Rebecca Adams Yasmin Harvey Tee Beng Keng Source Type: research

Acute leukemia with cytogenetically cryptic FGFR1 rearrangement and lineage switch during therapy: A case report and literature review
CONCLUSIONS: Ours is the only reported case of FGFR1-rearranged neoplasms with a disease sequence of acute myeloid leukemia transforming to B-cell acute lymphoblastic leukemia and 1 of only 3 reported cases with cytogenetically cryptic FGFR1 rearrangement. Fluorescence in situ hybridization testing for FGFR1 rearrangement should be a standard investigation in leukemia of mixed or switching lineage.PMID:37855739 | DOI:10.1093/ajcp/aqad135 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - October 19, 2023 Category: Pathology Authors: Sean J McKeague Kacey O'Rourke Stephen Fanning Christopher Joy Duncan Throp Rebecca Adams Yasmin Harvey Tee Beng Keng Source Type: research

Acute leukemia with cytogenetically cryptic FGFR1 rearrangement and lineage switch during therapy: A case report and literature review
CONCLUSIONS: Ours is the only reported case of FGFR1-rearranged neoplasms with a disease sequence of acute myeloid leukemia transforming to B-cell acute lymphoblastic leukemia and 1 of only 3 reported cases with cytogenetically cryptic FGFR1 rearrangement. Fluorescence in situ hybridization testing for FGFR1 rearrangement should be a standard investigation in leukemia of mixed or switching lineage.PMID:37855739 | DOI:10.1093/ajcp/aqad135 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - October 19, 2023 Category: Pathology Authors: Sean J McKeague Kacey O'Rourke Stephen Fanning Christopher Joy Duncan Throp Rebecca Adams Yasmin Harvey Tee Beng Keng Source Type: research

Acute leukemia with cytogenetically cryptic FGFR1 rearrangement and lineage switch during therapy: A case report and literature review
CONCLUSIONS: Ours is the only reported case of FGFR1-rearranged neoplasms with a disease sequence of acute myeloid leukemia transforming to B-cell acute lymphoblastic leukemia and 1 of only 3 reported cases with cytogenetically cryptic FGFR1 rearrangement. Fluorescence in situ hybridization testing for FGFR1 rearrangement should be a standard investigation in leukemia of mixed or switching lineage.PMID:37855739 | DOI:10.1093/ajcp/aqad135 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - October 19, 2023 Category: Pathology Authors: Sean J McKeague Kacey O'Rourke Stephen Fanning Christopher Joy Duncan Throp Rebecca Adams Yasmin Harvey Tee Beng Keng Source Type: research

A Korean family with RHD*DNT only detectable after anti-D alloimmunization
CONCLUSIONS: We recommend DNT individuals as candidates for Rh immune globulin prophylaxis during the perinatal period and transfusions with D- blood components. An anticipatory RHD genotyping is suggested for partial D family members to prevent potential partial D individuals from becoming alloimmunized.PMID:37852281 | DOI:10.1093/ajcp/aqad132 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - October 18, 2023 Category: Pathology Authors: Dong Woo Shin Gun-Hyuk Lee Hanah Kim Kyeong A So Yun Ji Hong Mina Hur Kyoung Un Park Source Type: research

A Korean family with RHD*DNT only detectable after anti-D alloimmunization
CONCLUSIONS: We recommend DNT individuals as candidates for Rh immune globulin prophylaxis during the perinatal period and transfusions with D- blood components. An anticipatory RHD genotyping is suggested for partial D family members to prevent potential partial D individuals from becoming alloimmunized.PMID:37852281 | DOI:10.1093/ajcp/aqad132 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - October 18, 2023 Category: Pathology Authors: Dong Woo Shin Gun-Hyuk Lee Hanah Kim Kyeong A So Yun Ji Hong Mina Hur Kyoung Un Park Source Type: research

Reply to "C-reactive protein and erythrocyte sedimentation rate in inflammatory lesions: erythrocyte sedimentation rate test is essential in a subset of patients"
Am J Clin Pathol. 2023 Oct 16:aqad126. doi: 10.1093/ajcp/aqad126. Online ahead of print.NO ABSTRACTPMID:37842811 | DOI:10.1093/ajcp/aqad126 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - October 16, 2023 Category: Pathology Authors: Dawi Shin Hyung J Cho Source Type: research

C-reactive protein and erythrocyte sedimentation rate in inflammatory lesions: Erythrocyte sedimentation rate test is essential in a subset of patients
Am J Clin Pathol. 2023 Oct 16:aqad125. doi: 10.1093/ajcp/aqad125. Online ahead of print.NO ABSTRACTPMID:37842812 | DOI:10.1093/ajcp/aqad125 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - October 16, 2023 Category: Pathology Authors: Gurmukh Singh Source Type: research

Large language model's utility in helping pathology professionals
Am J Clin Pathol. 2023 Oct 16:aqad130. doi: 10.1093/ajcp/aqad130. Online ahead of print.NO ABSTRACTPMID:37843400 | DOI:10.1093/ajcp/aqad130 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - October 16, 2023 Category: Pathology Authors: Hinpetch Daungsupawong Viroj Wiwanitkit Source Type: research

Reply to "C-reactive protein and erythrocyte sedimentation rate in inflammatory lesions: erythrocyte sedimentation rate test is essential in a subset of patients"
Am J Clin Pathol. 2023 Oct 16:aqad126. doi: 10.1093/ajcp/aqad126. Online ahead of print.NO ABSTRACTPMID:37842811 | DOI:10.1093/ajcp/aqad126 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - October 16, 2023 Category: Pathology Authors: Dawi Shin Hyung J Cho Source Type: research

C-reactive protein and erythrocyte sedimentation rate in inflammatory lesions: Erythrocyte sedimentation rate test is essential in a subset of patients
Am J Clin Pathol. 2023 Oct 16:aqad125. doi: 10.1093/ajcp/aqad125. Online ahead of print.NO ABSTRACTPMID:37842812 | DOI:10.1093/ajcp/aqad125 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - October 16, 2023 Category: Pathology Authors: Gurmukh Singh Source Type: research

Large language model's utility in helping pathology professionals
Am J Clin Pathol. 2023 Oct 16:aqad130. doi: 10.1093/ajcp/aqad130. Online ahead of print.NO ABSTRACTPMID:37843400 | DOI:10.1093/ajcp/aqad130 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - October 16, 2023 Category: Pathology Authors: Hinpetch Daungsupawong Viroj Wiwanitkit Source Type: research

Clinicopathologic characterization of cutaneous adult T-cell leukemia/lymphoma: A single tertiary care center experience in the United States
CONCLUSIONS: Pleomorphic large, atypical cells with CD4+/CD25+/CD7- immunophenotype from a non-"bathing trunk" location, especially in a patient from endemic regions, raise suspicion for ATLL. T-cell receptor gene rearrangement is almost always positive, and the neoplasm usually demonstrates multiple mutations by next-generation sequencing study.PMID:37830309 | DOI:10.1093/ajcp/aqad120 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - October 13, 2023 Category: Pathology Authors: Mitul B Modi Alexandra Kiszluk Jiani N Chai Ukuemi Edema Maxwell Y Ma R Alejandro Sica Yanhua Wang Yang Shi Source Type: research