American Journal of Clinical Pathology This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Morules and β-catenin predict POLE mutation status in endometrial cancer: A pathway to more cost-effective diagnostic procedures
CONCLUSIONS: Our findings suggest that the presence of either morules or nuclear β-catenin expression in EEC could practically rule out the presence of POLE mutations. These morphologic and immunohistochemical features can be used as preliminary screening tools for POLE mutations, offering significant savings in time and resources and potentially enhancing clinical decision-making and patient management strategies. However, further validation in larger, multi-institutional studies is required to fully understand the implications of these findings on clinical practice.PMID:38513273 | DOI:10.1093/ajcp/aqae023 (Source: Ameri...
Source: American Journal of Clinical Pathology - March 21, 2024 Category: Pathology Authors: Rujia Fan Wanrun Lin Ruijiao Zhao Li Li Rui Xin Yunfeng Zhang Yuxin Liu Ying Ma Yiying Wang Yue Wang Wenxin Zheng Source Type: research

Laboratory characterization of the pediatric B/T subtype of mixed-phenotype acute leukemia: Report of a case series
CONCLUSIONS: The accurate diagnosis of B/T MPAL requires a multidisciplinary approach combining high-tech laboratory methods and close cooperation between treating physicians and pathologists.PMID:38513276 | DOI:10.1093/ajcp/aqae020 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - March 21, 2024 Category: Pathology Authors: Irina Demina Ekaterina Mikhailova Elena Zerkalenkova Alexandra Semchenkova Julia Roumiantseva Alexandra Borkovskaya Evgeny Matveev Dmitry Abramov Dmitry Konovalov Natalia Miakova Natalia Ponomareva Julia Belkina Konstantin Kondratchik Yulia Olshanskaya Ga Source Type: research

Clinicopathologic correlation of dermatologic diseases in patients with darker pigmentation
CONCLUSIONS: As many clinicians are taught that there are no effective treatment options or that these diseases are considered "cosmetic" in nature, patients often do not get a thorough medical workup or skin biopsy. This article aims to decrease the knowledge gap and serve as a resource for anyone involved in the care of patients with these cutaneous conditions.PMID:38513285 | DOI:10.1093/ajcp/aqae013 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - March 21, 2024 Category: Pathology Authors: Sanjna Tripathy Elizabeth Warbasse Shira Ronen Rami Al-Rohil George F Cohen Wei-Shen Chen Anisha B Patel Source Type: research

How I diagnose and manage VEXAS syndrome
CONCLUSIONS: Either clinicians or pathologists may suspect a diagnosis of VEXAS syndrome depending on the clinical presentation and bone marrow findings. More studies are needed to determine the best therapeutic options, which are currently limited.PMID:38511841 | DOI:10.1093/ajcp/aqae017 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - March 21, 2024 Category: Pathology Authors: Ashley Hagiya Imran N Siddiqi Endi Wang Chuanyi M Lu Source Type: research

How Do I: The Academy of Clinical Laboratory Physicians and Scientists (ACLPS) publication series
Am J Clin Pathol. 2024 Mar 21:aqae006. doi: 10.1093/ajcp/aqae006. Online ahead of print.NO ABSTRACTPMID:38511852 | DOI:10.1093/ajcp/aqae006 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - March 21, 2024 Category: Pathology Authors: Amit A Gokhale Source Type: research