Correction to: Measuring the performance of an artificial intelligence-based robot that classifies blood tubes and performs quality control in terms of preanalytical errors: A preliminary study
Am J Clin Pathol. 2024 Feb 12:aqae025. doi: 10.1093/ajcp/aqae025. Online ahead of print.NO ABSTRACTPMID:38345151 | DOI:10.1093/ajcp/aqae025 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - February 12, 2024 Category: Pathology Source Type: research

5-Hydroxymethylcytosine (5-hmC) loss is a marker of malignancy in biliary neoplasms
CONCLUSIONS: Loss of 5-hmC is not unique to intrahepatic cholangiocarcinoma among biliary carcinomas, but is a useful diagnostic marker differentiating malignancies of the biliary tree from benign mimics.PMID:38345293 | DOI:10.1093/ajcp/aqae001 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - February 12, 2024 Category: Pathology Authors: Miguel S Gonzalez-Mancera Andrew Siref Kambiz Kosari Nicholas Nissen Srinivas Gaddam Andrew Hendifar Arsen Osipov Kevin Waters Danielle Hutchings Maha Guindi Brent K Larson Source Type: research

Characterizing the role of informal payments in the delivery of pathology and clinical laboratory services
CONCLUSIONS: This represents a first step in characterizing IPs within PALM and how this practice may affect access to these services in LMICs. Specifically, the fact that faster turnaround time was the most frequently perceived reason for offering IPs uncovers a potential barrier to improving PALM capacity in these regions.PMID:38345305 | DOI:10.1093/ajcp/aqad188 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - February 12, 2024 Category: Pathology Authors: Emily H Glynn Timothy Amukele Olusegun Soge Geoffrey Baird Taryn Vian Source Type: research

Characterization of T-/natural killer cell lymphoproliferative neoplasms associated with systemic, chronic, active Epstein-Barr virus in adults: A report of 5 cases in a Western population
CONCLUSIONS: This diagnosis is most prevalent in Asia, with few cases reported in Western countries. Adult age is an independent risk factor for poor outcomes, and most cases are diagnosed in pediatric populations.PMID:38345307 | DOI:10.1093/ajcp/aqad184 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - February 12, 2024 Category: Pathology Authors: Carlos Murga-Zamalloa Michael Brandon Stone Marc G Gutierrez Neha Rajendra Hippalgaonkar Hamza Tariq Morteza Sadeh Ankit Mehta Irum Khan Serhan Alkan Kedar V Inamdar Ryan Wilcox Amir Behdad Source Type: research

Good correlation between tacrolimus concentrations using improved CMIA on the Alinity i analyzer and LC-MS/MS method from a reference laboratory but unexpected negative bias with another LC-MS/MS method from a different reference laboratory
CONCLUSIONS: Because of good correlation of tacrolimus concentrations using the CMIA and LC-MS/MS from reference laboratory A, our long-term reference laboratory for drug analysis, we concluded that the CMIA on the Alinity i can be used for therapeutic drug monitoring of tacrolimus.PMID:38346092 | DOI:10.1093/ajcp/aqae005 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - February 12, 2024 Category: Pathology Authors: Kelsey Woodard Tracey Kisler Amitava Dasgupta Source Type: research

Occult cancer in patients with unprovoked venous thromboembolism: A nested case-control study
CONCLUSIONS: The combination of sP-selectin and D-dimer can be a valuable biomarker in detecting occult cancer in patients with unprovoked VTE. Further research is necessary to ascertain whether easily measurable biomarkers such as sP-selectin and D-dimer can effectively distinguish between patients who have VTE with and without hidden malignancies.PMID:38340336 | DOI:10.1093/ajcp/aqad178 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - February 10, 2024 Category: Pathology Authors: Ver ónica Sánchez-López Samira Mar ín-Romero Marta Ferrer-Galv án Teresa El ías-Hernández Jos é Luis Lobo Beristain Aitor Ballaz Quincoces Luis Jara-Palomares Francisco Javier Rodr íguez Martorell Mar ía José Castro Carmen Mar ín Hinojosa Jos Source Type: research

Banff scoring of kidney allograft biopsies: "Manual" application vs software-assisted sign-out
CONCLUSIONS: Compared with the legacy approach, software-assisted sign-out improves Banff accuracy and fidelity, more closely correlates with kidney function, is practical for routine clinical work and translational research studies, facilitates downstream integration with nonpathology data, and readies biopsy scoring for artificial intelligence algorithms.PMID:38340346 | DOI:10.1093/ajcp/aqad180 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - February 10, 2024 Category: Pathology Authors: Anthony J Demetris Andrew J Lesniak Benjamin A Popp Ronald J Frencho Marta I Minervini Michael A Nalesnik Mohamed I El Hag Sundaram Hariharan Parmjeet S Randhawa Source Type: research

The role of multidisciplinary team meeting histopathology review and its impact on revised reports: Analysis of a national quality improvement program
CONCLUSIONS: The multidisciplinary team meeting review process plays a valuable role in pathology error detection. A pathologist's participation in the review process comes with a clinically significant workload that needs to be recognized for future workforce planning. This study highlighted the positive role pathologists play in enhancing patient safety.PMID:38330196 | DOI:10.1093/ajcp/aqad183 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - February 8, 2024 Category: Pathology Authors: Eoghan O'Connor Ann Treacy Aine Mitchell Niall Swan Source Type: research

Measuring the performance of an artificial intelligence-based robot that classifies blood tubes and performs quality control in terms of preanalytical errors: A preliminary study
CONCLUSIONS: KANKA categorizes and records problem-free tubes according to laboratory subunits while identifying and classifying tubes with preanalytical inappropriateness into the correct error sections. As a blood acceptance and tube sorting system, KANKA has the potential to save labor and enhance the quality of the preanalytical process.PMID:38284629 | DOI:10.1093/ajcp/aqad179 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - January 29, 2024 Category: Pathology Authors: Ali R ıza Şişman Banu İşbilen Başok İnanç Kara Ayfer Çolak U ğur Bilge Ferhat Demirci Nuri Ba şoglu Source Type: research

Current gross examination and reporting patterns of post-neoadjuvant chemotherapy cystectomy specimens: Is it time for a standardized approach?
CONCLUSIONS: With the increased use of NACT, lack of any gross lesion leads to inconsistent gross examination techniques. This study provides insight into the current approach to examination of post-NACT cystectomies and suggests that a desire exists among pathologists and pathologists' assistants for more standardized practice.PMID:38240078 | DOI:10.1093/ajcp/aqad176 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - January 19, 2024 Category: Pathology Authors: Katherine E Saunders Nicola Gerken Francesca Khani Sean R Williamson Sara E Wobker Source Type: research

Clinical and pathologic features of Sturge-Weber syndrome in patients with refractory epilepsy
CONCLUSIONS: Calcification of leptomeningeal arteries, focal cortical dysplasia, and GNAQ alteration are common features in SWS pathology. Patients with refractory epilepsy caused by SWS can achieve satisfactory seizure control after surgery, but seizure control was compromised in patients with comorbid HS.PMID:38217527 | DOI:10.1093/ajcp/aqad174 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - January 13, 2024 Category: Pathology Authors: Zejun Duan Ke Xu Mingguo Xie Xiaolin Tian Xiongfei Wang Jing Feng Yuguang Guan Jian Zhou Guoming Luan Xueling Qi Dehong Lu Source Type: research

Nonneoplastic pathology of the appendix: A review article, based on the recent literature
CONCLUSIONS: Most importantly, all pathologists should appreciate that the appendix is not as "routine" a specimen as one would want to believe.PMID:38217538 | DOI:10.1093/ajcp/aqad175 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - January 13, 2024 Category: Pathology Authors: Sanjay A Pai Rifat Mannan Source Type: research

Utilizing PTEN immunohistochemistry as a screening test for Cowden syndrome
CONCLUSIONS: PTEN immunohistochemistry on CS-associated tumors, especially trichilemmomas, can serve as a readily accessible and cost-effective screening test for CS.PMID:38206110 | DOI:10.1093/ajcp/aqad177 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - January 11, 2024 Category: Pathology Authors: Emily Hartsough Mia S DeSimone Mayra E Lorenzo Dora Dias-Santagata Vania Nose Mai P Hoang Source Type: research

Development of an open access, virtual bioinformatics lab for students in medical laboratory sciences
CONCLUSIONS: Our learning unit is a promising tool for introducing MLS students to the field of bioinformatics. As an open educational resource, it has the potential to be integrated into molecular biology education for MLS programs anywhere.PMID:38141225 | DOI:10.1093/ajcp/aqad166 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - December 23, 2023 Category: Pathology Authors: Hana S Fukuto Gloria I Viboud Source Type: research

Development of an open access, virtual bioinformatics lab for students in medical laboratory sciences
CONCLUSIONS: Our learning unit is a promising tool for introducing MLS students to the field of bioinformatics. As an open educational resource, it has the potential to be integrated into molecular biology education for MLS programs anywhere.PMID:38141225 | DOI:10.1093/ajcp/aqad166 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - December 23, 2023 Category: Pathology Authors: Hana S Fukuto Gloria I Viboud Source Type: research