American Journal of Clinical Pathology 
This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.
This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.Clinicopathologic features and survival outcomes of CD30 expression in extranodal natural killer/T-cell lymphoma
CONCLUSIONS: Positive CD30 expression was a favorable prognostic factor for ENKTL, and CD30 expression could restratify the survival of patients in clinical subgroups.PMID:38387041 | DOI:10.1093/ajcp/aqae012 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - February 22, 2024 Category: Pathology Authors: Ziyuan Shen Yubo Wang Ruiyang Xie Qing Zhang Xing Xing Shuo Zhang Hui Liu Wei Sang Source Type: research
MED15::TFE3 fusion renal cell carcinoma with extensive cystic change: A clinicopathologic and molecular genetic study of 2 cases, with an emphasis on differential diagnosis
CONCLUSIONS: The main differential diagnosis of MED15::TFE3 fusion RCC includes multilocular cystic renal neoplasm of low malignant potential and atypical renal cysts. Molecular confirmation of TFE3 fusion is essential for establishing the correct diagnosis.PMID:38387043 | DOI:10.1093/ajcp/aqae011 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - February 22, 2024 Category: Pathology Authors: Xiaona Yin Xingen Hu Jiayun Xu Danting Xiong Ming Zhao Source Type: research
Artificial intelligence-based algorithms for the diagnosis of prostate cancer: A systematic review
CONCLUSIONS: The published evidence suggests that AI can be reliably used for prostate cancer detection and grading, assisting pathologists in the time-consuming screening of slides. Further technologic improvement would help widening AI's adoption in prostate pathology, as well as expanding its prognostic predictive potential.PMID:38381582 | DOI:10.1093/ajcp/aqad182 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - February 21, 2024 Category: Pathology Authors: Stefano Marletta Albino Eccher Filippo Maria Martelli Nicola Santonicco Ilaria Girolami Aldo Scarpa Fabio Pagni Vincenzo L'Imperio Liron Pantanowitz Stefano Gobbo Davide Seminati Angelo Paolo Dei Tos Anil Parwani Source Type: research
Immune checkpoint inhibitor-related colitis in patients on immunotherapy for cancer
CONCLUSIONS: Future successful management of this form of colitis relies on our comprehension of the intricate interplay between tumoral and systemic immune responses to immune checkpoint inhibitors and innovative approaches to modify these responses, along with specific immune cell populations, to preclude immune-related adverse events while achieving antitumor therapeutic outcomes.PMID:38377034 | DOI:10.1093/ajcp/aqae002 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - February 20, 2024 Category: Pathology Authors: Belinda L Sun Alexis S Elliott David Nolte Xiaoguang Sun Source Type: research
Immune checkpoint inhibitor-related colitis in patients on immunotherapy for cancer
CONCLUSIONS: Future successful management of this form of colitis relies on our comprehension of the intricate interplay between tumoral and systemic immune responses to immune checkpoint inhibitors and innovative approaches to modify these responses, along with specific immune cell populations, to preclude immune-related adverse events while achieving antitumor therapeutic outcomes.PMID:38377034 | DOI:10.1093/ajcp/aqae002 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - February 20, 2024 Category: Pathology Authors: Belinda L Sun Alexis S Elliott David Nolte Xiaoguang Sun Source Type: research
Multicolor flow cytometric immunophenotyping is highly sensitive and specific in identifying aberrant mast cells in the diagnostic workup of systemic mastocytosis
CONCLUSIONS: Flow cytometric immunophenotyping is a quick, sensitive, high-yield tool for evaluating the immunophenotype of mast cells. An abnormal FCI finding should prompt careful histologic evaluation and sensitive KIT D816V mutation testing to address the possibility of SM. CD2, CD25, and CD30 are important markers for the detection of immunophenotypic aberrancy of mast cells, and their frequencies of aberrancy differ across SM subtypes.PMID:38372648 | DOI:10.1093/ajcp/aqad187 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - February 19, 2024 Category: Pathology Authors: Okechukwu Valentine Nwogbo Hong Fang Wei Wang Jie Xu Roberto N Miranda Prithviraj Bose Chi Young Ok Jeffrey L Jorgensen L Jeffrey Medeiros Sa A Wang Source Type: research
To normalize or not?: Dilute Russell viper venom time testing
CONCLUSIONS: The lupus anticoagulant status by the dRVVT assay was not changed based on normalization. Normalization was of no clinical benefit in our patient population; therefore, there was no need for the extra calculation step. Normalization may be useful for intermethod and interlaboratory studies and not for within-method LA detection.PMID:38372653 | DOI:10.1093/ajcp/aqae004 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - February 19, 2024 Category: Pathology Authors: Yong Zhang Michael Creer Olajumoke O Oladipo Source Type: research
Multicolor flow cytometric immunophenotyping is highly sensitive and specific in identifying aberrant mast cells in the diagnostic workup of systemic mastocytosis
CONCLUSIONS: Flow cytometric immunophenotyping is a quick, sensitive, high-yield tool for evaluating the immunophenotype of mast cells. An abnormal FCI finding should prompt careful histologic evaluation and sensitive KIT D816V mutation testing to address the possibility of SM. CD2, CD25, and CD30 are important markers for the detection of immunophenotypic aberrancy of mast cells, and their frequencies of aberrancy differ across SM subtypes.PMID:38372648 | DOI:10.1093/ajcp/aqad187 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - February 19, 2024 Category: Pathology Authors: Okechukwu Valentine Nwogbo Hong Fang Wei Wang Jie Xu Roberto N Miranda Prithviraj Bose Chi Young Ok Jeffrey L Jorgensen L Jeffrey Medeiros Sa A Wang Source Type: research
To normalize or not?: Dilute Russell viper venom time testing
CONCLUSIONS: The lupus anticoagulant status by the dRVVT assay was not changed based on normalization. Normalization was of no clinical benefit in our patient population; therefore, there was no need for the extra calculation step. Normalization may be useful for intermethod and interlaboratory studies and not for within-method LA detection.PMID:38372653 | DOI:10.1093/ajcp/aqae004 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - February 19, 2024 Category: Pathology Authors: Yong Zhang Michael Creer Olajumoke O Oladipo Source Type: research
AmpFire HPV and ScreenFire RS HPV validation trial
CONCLUSIONS: The excellent intra- and interlaboratory reproducibility and the established clinical performance, together with the platforms' simplicity, make these assays particularly applicable to low-resource settings.PMID:38365314 | DOI:10.1093/ajcp/aqad181 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - February 16, 2024 Category: Pathology Authors: Jun Hou Jerome L Belinson Hui Du Changzhong Li Wei Zhang Lijie Zhang Yi Zhang Xinfeng Qu Ruifang Wu Source Type: research
AmpFire HPV and ScreenFire RS HPV validation trial
CONCLUSIONS: The excellent intra- and interlaboratory reproducibility and the established clinical performance, together with the platforms' simplicity, make these assays particularly applicable to low-resource settings.PMID:38365314 | DOI:10.1093/ajcp/aqad181 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - February 16, 2024 Category: Pathology Authors: Jun Hou Jerome L Belinson Hui Du Changzhong Li Wei Zhang Lijie Zhang Yi Zhang Xinfeng Qu Ruifang Wu Source Type: research
Assessing the feasibility of a multimodal liquid biopsy for the diagnosis of HPV-associated oropharyngeal squamous cell carcinoma
CONCLUSIONS: Compared to HPV RNA ISH, HPV serology and ctHPVDNA are sensitive and highly specific biomarkers for HPV-associated OPSCC at the time of presentation.PMID:38349613 | DOI:10.1093/ajcp/aqad185 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - February 13, 2024 Category: Pathology Authors: James S Lewis Saskia Naegele Vasileios Efthymiou Mitra Mehrad Kim A Ely Tim Waterboer Krystle A Lang Kuhs Seth J Davis Kelsey Richard Dipon Das Daniel L Faden Source Type: research
Assessing the feasibility of a multimodal liquid biopsy for the diagnosis of HPV-associated oropharyngeal squamous cell carcinoma
CONCLUSIONS: Compared to HPV RNA ISH, HPV serology and ctHPVDNA are sensitive and highly specific biomarkers for HPV-associated OPSCC at the time of presentation.PMID:38349613 | DOI:10.1093/ajcp/aqad185 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - February 13, 2024 Category: Pathology Authors: James S Lewis Saskia Naegele Vasileios Efthymiou Mitra Mehrad Kim A Ely Tim Waterboer Krystle A Lang Kuhs Seth J Davis Kelsey Richard Dipon Das Daniel L Faden Source Type: research
Assessing the feasibility of a multimodal liquid biopsy for the diagnosis of HPV-associated oropharyngeal squamous cell carcinoma
CONCLUSIONS: Compared to HPV RNA ISH, HPV serology and ctHPVDNA are sensitive and highly specific biomarkers for HPV-associated OPSCC at the time of presentation.PMID:38349613 | DOI:10.1093/ajcp/aqad185 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - February 13, 2024 Category: Pathology Authors: James S Lewis Saskia Naegele Vasileios Efthymiou Mitra Mehrad Kim A Ely Tim Waterboer Krystle A Lang Kuhs Seth J Davis Kelsey Richard Dipon Das Daniel L Faden Source Type: research
Correction to: Measuring the performance of an artificial intelligence-based robot that classifies blood tubes and performs quality control in terms of preanalytical errors: A preliminary study
Am J Clin Pathol. 2024 Feb 12:aqae025. doi: 10.1093/ajcp/aqae025. Online ahead of print.NO ABSTRACTPMID:38345151 | DOI:10.1093/ajcp/aqae025 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - February 12, 2024 Category: Pathology Source Type: research
