Proton Pump Inhibitors and Kidney Disease: Fact or Fiction?
Am J Nephrol. 2024 Apr 6. doi: 10.1159/000538755. Online ahead of print.ABSTRACTBACKGROUND: Proton pump inhibitors (PPI) are commonly prescribed medications for dyspepsia and gastroesophageal reflux. There are concerns about their use in the development of chronic kidney disease (CKD).SUMMARY: The available published literature fails to support an association with PPI and the development of CKD. Placebo-controlled trials demonstrate no difference on the incidence of CKD between placebo and PPI. If one examines the data according to the Bradford Hill perspective incorporating temporal relationship, strength of association, ...
Source: American Journal of Nephrology - April 7, 2024 Category: Urology & Nephrology Authors: Matthew Ryan Weir Source Type: research
Proton Pump Inhibitors and Kidney Disease: Fact or Fiction?
Am J Nephrol. 2024 Apr 6. doi: 10.1159/000538755. Online ahead of print.ABSTRACTBACKGROUND: Proton pump inhibitors (PPI) are commonly prescribed medications for dyspepsia and gastroesophageal reflux. There are concerns about their use in the development of chronic kidney disease (CKD).SUMMARY: The available published literature fails to support an association with PPI and the development of CKD. Placebo-controlled trials demonstrate no difference on the incidence of CKD between placebo and PPI. If one examines the data according to the Bradford Hill perspective incorporating temporal relationship, strength of association, ...
Source: American Journal of Nephrology - April 7, 2024 Category: Urology & Nephrology Authors: Matthew Ryan Weir Source Type: research
Proton Pump Inhibitors and Kidney Disease: Fact or Fiction?
Am J Nephrol. 2024 Apr 6. doi: 10.1159/000538755. Online ahead of print.ABSTRACTBACKGROUND: Proton pump inhibitors (PPI) are commonly prescribed medications for dyspepsia and gastroesophageal reflux. There are concerns about their use in the development of chronic kidney disease (CKD).SUMMARY: The available published literature fails to support an association with PPI and the development of CKD. Placebo-controlled trials demonstrate no difference on the incidence of CKD between placebo and PPI. If one examines the data according to the Bradford Hill perspective incorporating temporal relationship, strength of association, ...
Source: American Journal of Nephrology - April 7, 2024 Category: Urology & Nephrology Authors: Matthew Ryan Weir Source Type: research
Proton Pump Inhibitors and Kidney Disease: Fact or Fiction?
Am J Nephrol. 2024 Apr 6. doi: 10.1159/000538755. Online ahead of print.ABSTRACTBACKGROUND: Proton pump inhibitors (PPI) are commonly prescribed medications for dyspepsia and gastroesophageal reflux. There are concerns about their use in the development of chronic kidney disease (CKD).SUMMARY: The available published literature fails to support an association with PPI and the development of CKD. Placebo-controlled trials demonstrate no difference on the incidence of CKD between placebo and PPI. If one examines the data according to the Bradford Hill perspective incorporating temporal relationship, strength of association, ...
Source: American Journal of Nephrology - April 7, 2024 Category: Urology & Nephrology Authors: Matthew Ryan Weir Source Type: research
Proton Pump Inhibitors and Kidney Disease: Fact or Fiction?
Am J Nephrol. 2024 Apr 6. doi: 10.1159/000538755. Online ahead of print.ABSTRACTBACKGROUND: Proton pump inhibitors (PPI) are commonly prescribed medications for dyspepsia and gastroesophageal reflux. There are concerns about their use in the development of chronic kidney disease (CKD).SUMMARY: The available published literature fails to support an association with PPI and the development of CKD. Placebo-controlled trials demonstrate no difference on the incidence of CKD between placebo and PPI. If one examines the data according to the Bradford Hill perspective incorporating temporal relationship, strength of association, ...
Source: American Journal of Nephrology - April 7, 2024 Category: Urology & Nephrology Authors: Matthew Ryan Weir Source Type: research
Association of Sevelamer Initiation with Gastrointestinal Bleeding Hospitalization in Individuals Requiring Hemodialysis
Conclusion Among patients requiring hemodialysis, sevelamer (vs non-sevelamer) containing phosphate binders was not associated with increased risk of GIB hospitalization.PMID:38555633 | DOI:10.1159/000538253 (Source: American Journal of Nephrology)
Source: American Journal of Nephrology - March 31, 2024 Category: Urology & Nephrology Authors: Dustin Le Deidra C Crews Morgan E Grams Josef Coresh Jung-Im Shin Source Type: research
Association of Sevelamer Initiation with Gastrointestinal Bleeding Hospitalization in Individuals Requiring Hemodialysis
Conclusion Among patients requiring hemodialysis, sevelamer (vs non-sevelamer) containing phosphate binders was not associated with increased risk of GIB hospitalization.PMID:38555633 | DOI:10.1159/000538253 (Source: American Journal of Nephrology)
Source: American Journal of Nephrology - March 31, 2024 Category: Urology & Nephrology Authors: Dustin Le Deidra C Crews Morgan E Grams Josef Coresh Jung-Im Shin Source Type: research
Association of Sevelamer Initiation with Gastrointestinal Bleeding Hospitalization in Individuals Requiring Hemodialysis
Conclusion Among patients requiring hemodialysis, sevelamer (vs non-sevelamer) containing phosphate binders was not associated with increased risk of GIB hospitalization.PMID:38555633 | DOI:10.1159/000538253 (Source: American Journal of Nephrology)
Source: American Journal of Nephrology - March 31, 2024 Category: Urology & Nephrology Authors: Dustin Le Deidra C Crews Morgan E Grams Josef Coresh Jung-Im Shin Source Type: research
Association of Sevelamer Initiation with Gastrointestinal Bleeding Hospitalization in Individuals Requiring Hemodialysis
Conclusion Among patients requiring hemodialysis, sevelamer (vs non-sevelamer) containing phosphate binders was not associated with increased risk of GIB hospitalization.PMID:38555633 | DOI:10.1159/000538253 (Source: American Journal of Nephrology)
Source: American Journal of Nephrology - March 31, 2024 Category: Urology & Nephrology Authors: Dustin Le Deidra C Crews Morgan E Grams Josef Coresh Jung-Im Shin Source Type: research
Association of Sevelamer Initiation with Gastrointestinal Bleeding Hospitalization in Individuals Requiring Hemodialysis
Conclusion Among patients requiring hemodialysis, sevelamer (vs non-sevelamer) containing phosphate binders was not associated with increased risk of GIB hospitalization.PMID:38555633 | DOI:10.1159/000538253 (Source: American Journal of Nephrology)
Source: American Journal of Nephrology - March 31, 2024 Category: Urology & Nephrology Authors: Dustin Le Deidra C Crews Morgan E Grams Josef Coresh Jung-Im Shin Source Type: research
Association of Sevelamer Initiation with Gastrointestinal Bleeding Hospitalization in Individuals Requiring Hemodialysis
Conclusion Among patients requiring hemodialysis, sevelamer (vs non-sevelamer) containing phosphate binders was not associated with increased risk of GIB hospitalization.PMID:38555633 | DOI:10.1159/000538253 (Source: American Journal of Nephrology)
Source: American Journal of Nephrology - March 31, 2024 Category: Urology & Nephrology Authors: Dustin Le Deidra C Crews Morgan E Grams Josef Coresh Jung-Im Shin Source Type: research
The risk factors and clinical outcomes in hepatitis B seropositive and seronegative renal transplant patients
Conclusion: Individuals, independent of HBsAg status, had similar prognosis in terms of patient and graft survival, acute rejection rate, and cancer development. The absence of either pre-transplant anti-HBV medication or lifelong antiviral therapy was significantly associated with an increased risk of HBV reactivation.PMID:38498992 | DOI:10.1159/000538231 (Source: American Journal of Nephrology)
Source: American Journal of Nephrology - March 18, 2024 Category: Urology & Nephrology Authors: Yu-Lien Tsai Meng-Hsuan Chung Niang-Cheng Lin Cheng-Yen Chen Yao-Ping Lin Ming-Tsun Tsai Hsin-Lin Tsai Yee-An Chen Shuo-Ming Ou Chi-Jen Chu Tsai-Hung Wu Chang-Youh Tsai Source Type: research
Acute and chronic kidney dysfunction and prognosis following thrombectomy for ischemic stroke
CONCLUSION: AKI is independently associated with poorer functional outcome and increased mortality at 3 months. CKD was not an independent risk factor for 3-month mortality or poor functional prognosis.PMID:38499002 | DOI:10.1159/000536493 (Source: American Journal of Nephrology)
Source: American Journal of Nephrology - March 18, 2024 Category: Urology & Nephrology Authors: Micka ël Bobot Jean-Fran çois Hak Barbara Casolla Jean-Daniel Dehondt St éphane Burtey Emilie Doche Laurent Suissa Source Type: research
The risk factors and clinical outcomes in hepatitis B seropositive and seronegative renal transplant patients
Conclusion: Individuals, independent of HBsAg status, had similar prognosis in terms of patient and graft survival, acute rejection rate, and cancer development. The absence of either pre-transplant anti-HBV medication or lifelong antiviral therapy was significantly associated with an increased risk of HBV reactivation.PMID:38498992 | DOI:10.1159/000538231 (Source: American Journal of Nephrology)
Source: American Journal of Nephrology - March 18, 2024 Category: Urology & Nephrology Authors: Yu-Lien Tsai Meng-Hsuan Chung Niang-Cheng Lin Cheng-Yen Chen Yao-Ping Lin Ming-Tsun Tsai Hsin-Lin Tsai Yee-An Chen Shuo-Ming Ou Chi-Jen Chu Tsai-Hung Wu Chang-Youh Tsai Source Type: research
Acute and chronic kidney dysfunction and prognosis following thrombectomy for ischemic stroke
CONCLUSION: AKI is independently associated with poorer functional outcome and increased mortality at 3 months. CKD was not an independent risk factor for 3-month mortality or poor functional prognosis.PMID:38499002 | DOI:10.1159/000536493 (Source: American Journal of Nephrology)
Source: American Journal of Nephrology - March 18, 2024 Category: Urology & Nephrology Authors: Micka ël Bobot Jean-Fran çois Hak Barbara Casolla Jean-Daniel Dehondt St éphane Burtey Emilie Doche Laurent Suissa Source Type: research
