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402 records returned

Pregnancy Does not Deter the Development of a Potent Maternal Protective CD8+ T-Cell Acquired Immune Response Against Listeria Monocytogenes Despite Preferential Placental Colonizationemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion Maternal hosts generate a normal Listeria-specific adaptive immunity in particular CD8+ T-cell memory response suggesting that systemic listeriosis during pregnancy may be an immunopathology associated with placental infection. (Source: American Journal of Reproductive Immunology)
Source: American Journal of Reproductive Immunology - November 13, 2009 Category: Allergy & Immunology Authors: Lakshmi Krishnan, Branka Pejcic-Karapetrovic, Komal Gurnani, Ahmed Zafer, Subash Sad Source Type: journals

Predictors of Inflammatory Breast Diseases During Lactation – Results of a Cohort Studyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion Higher maternal age, postpartum increase in stress perception and low number of leucocytes are associated with a higher incidence of inflammatory breast diseases. Further studies must examine the causality of this effect. (Source: American Journal of Reproductive Immunology)
Source: American Journal of Reproductive Immunology - November 12, 2009 Category: Allergy & Immunology Authors: Achim Wöckel, Anna Beggel, Miriam Rücke, Michael Abou-Dakn, Petra Arck Source Type: journals

Imbalance of T-cell Transcription Factors Contributes to the Th1 Type Immunity Predominant in Pre-eclampsiaemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion Decreased expression of FOXP3 mRNA and increased expression of T-bet mRNA may contribute to Th1 type immunity predominant in pre-eclampsia. (Source: American Journal of Reproductive Immunology)
Source: American Journal of Reproductive Immunology - November 12, 2009 Category: Allergy & Immunology Authors: Zhou Jianjun, Hu Yali, Wang Zhiqun, Zheng Mingming, Zhao Xia Source Type: journals

Comparative Analysis of Peripheral Natural Killer Cells in the Two Phases of the Ovarian Cycleemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion The study did not reveal menstrual cycle-depended changes in PB NK cells. Thus, a suggestion to measure these cells in a specific phase of the cycle in order to predict the outcome of a subsequent pregnancy in women with fertility problems is objected. (Source: American Journal of Reproductive Immunology)
Source: American Journal of Reproductive Immunology - November 12, 2009 Category: Allergy & Immunology Authors: Ageliki Pantazi, Panagiotis Tzonis, Gerasimos Perros, Olga Graphou, Theodora Keramitsoglou, Stavros Koussoulakos, Loukas Margaritis, Marighoula Varla-Leftherioti Source Type: journals

A Prospective Case–Control Study Analyzes 12 Thrombophilic Gene Mutations in Turkish Couples with Recurrent Pregnancy Lossemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion In contrast to the other mutations and polymorphisms, FV Leiden, FXIII V34L, GPIIIa L33P, Apo E, prothrombin G20210A, PAI-1 and MTHFR C677T gene mutations may help to identify the couples at risk for recurrent pregnancy loss. (Source: American Journal of Reproductive Immunology)
Source: American Journal of Reproductive Immunology - November 11, 2009 Category: Allergy & Immunology Authors: Gonca Imir Yenicesu, Meral Cetin, Ozturk Ozdemir, Ali Cetin, Filiz Ozen, Cem Yenicesu, Caglar Yildiz, Nadir Kocak Source Type: journals

Phenotypic Characterization of Macrophages in the Endometrium of the Pregnant Cowemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion CD68+CD14+ macrophages present in the stroma of the interplacentomal endometrium and caruncular septa of the placentome are regionally differentiated with regard to expression of CD11b and MHC class II. (Source: American Journal of Reproductive Immunology)
Source: American Journal of Reproductive Immunology - November 6, 2009 Category: Allergy & Immunology Authors: Lilian J. Oliveira, Peter J. Hansen Tags: Original Articles Source Type: journals

Urgent Termination of Pregnancy in Pre-eclampsia and Panel of Antiphospholipid Antibodiesemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion Supposed increase in various antiphospholipid antibodies (aPLs) levels due to the stress during the short time of admission and a need for a quick medical decision to terminate the pregnancy was not unambiguously proven, but our results are evidently influenced by the current urgent life-saving treatment. (Source: American Journal of Reproductive Immunology)
Source: American Journal of Reproductive Immunology - November 6, 2009 Category: Allergy & Immunology Authors: Libor Hradecky, Ivan Subrt, Zdenka Ulcova-Gallova Tags: Original Articles Source Type: journals

Effect of Maternal Immunopotentiation on Apoptosis-Associated Molecules Expression in Teratogen-Treated Embryosemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion Our data implicate maternal immunopotentiation to protect the embryo against teratogenic insults, possibly through its effect on the expression of p65, bcl-2 or p53. (Source: American Journal of Reproductive Immunology)
Source: American Journal of Reproductive Immunology - November 6, 2009 Category: Allergy & Immunology Authors: Shoshana Savion, Ilan Aroch, Keren Mammon, Hasida Orenstein, Amos Fein, Arkady Torchinsky, Vladimir Toder Tags: Original Articles Source Type: journals

Thrombin Activatable Fibrinolysis Inhibitor and Clot Lysis Time in Pregnant Patients with Antiphospholipid Syndrome: Relationship with Pregnancy Outcome and Thrombosisemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion Patients with APS have impairment in fibrinolysis evidenced by prolonged CLT at baseline. TAFI and CLT do not seem to be useful as markers of obstetric outcome or risk of thrombosis in patients with APS. (Source: American Journal of Reproductive Immunology)
Source: American Journal of Reproductive Immunology - November 6, 2009 Category: Allergy & Immunology Authors: Maria Angeles Martinez-Zamora, Dolors Tassies, Francisco Carmona, Gerard Espinosa, Ricard Cervera, Juan Carlos Reverter, Juan Balasch Tags: Original Articles Source Type: journals

What the Sperm Says and the Egg Hears – A Tale of Two Proteins and Moreemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
While considerable information exists regarding the early interactions of spermatozoon and egg that lead to successful fertilization, the molecular biology of events that result in the incorporation of the spermatozoon within the cortical ooplasm is largely undefined. There is circumstantial evidence suggesting that this process involves the interactions of specific oolemmal receptors and their ligands on sperm that bear similarities to mechanisms used in phagocytosis by macrophages. We have postulated that the egg may act as a 'non-professional phagocyte' during its association with the spermatozoon. This review surveys t...
Source: American Journal of Reproductive Immunology - November 6, 2009 Category: Allergy & Immunology Authors: Richard Bronson Tags: Review Article Source Type: journals

Increased Expression of Glutathione by Estradiol, Tumor Necrosis Factor-Alpha, and Interleukin 1-Beta in Endometrial Stromal Cellsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions These findings might suggest that increased production of estradiol and proinflammatory cytokines in the peritoneal cavity possibly leads to the establishment of endometriosis through increased level of GSH. (Source: American Journal of Reproductive Immunology)
Source: American Journal of Reproductive Immunology - November 6, 2009 Category: Allergy & Immunology Authors: Sa Ra Lee, Sung Hoon Kim, Hoi Woul Lee, Young-Hoon Kim, Hee Dong Chae, Chung-Hoon Kim, Byung Moon Kang Tags: Short Communications Source Type: journals

Response to Gerard Chaouat: Primum Non Nocera*email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
(Source: American Journal of Reproductive Immunology)
Source: American Journal of Reproductive Immunology - October 14, 2009 Category: Allergy & Immunology Authors: Edward E. Winger, Jane L. Reed Source Type: journals

IL-10 Modulates Placental Responses to TLR Ligandsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions Our results demonstrate that placental exposure to LTA and LPS appear to trigger distinct cytokine responses that can be modulated by IL-10. (Source: American Journal of Reproductive Immunology)
Source: American Journal of Reproductive Immunology - October 11, 2009 Category: Allergy & Immunology Authors: Mehmet Bayraktar, Morgan Peltier, Anna Vetrano, Yuko Arita, Ellen Gurzenda, Ansamma Joseph, Jeffrey Kazzaz, Surendra Sharma, Nazeeh Hanna Source Type: journals

Are Polymorphisms in the ACE and PAI-1 Genes Associated with Recurrent Spontaneous Miscarriages?email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion Homozygosity for the D allele of the ACE gene and the combination of the D/D genotype with two 4G alleles of the PAI-1 promoter gene are not associated with a significant increase in the risk of recurrent miscarriage. (Source: American Journal of Reproductive Immunology)
Source: American Journal of Reproductive Immunology - October 10, 2009 Category: Allergy & Immunology Authors: Chelsi Goodman, Jee Hur, Cyle S. Goodman, Rajasingham S. Jeyendran, Carolyn Coulam Source Type: journals

Correlation Between Natural Cytotoxicity Receptors and Intracellular Cytokine Expression of Peripheral Blood NK Cells in Women with Recurrent Pregnancy Losses and Implantation Failuresemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion Recurrent pregnancy losses and implantation failures have lack of, or negative correlation between NCRs and intracellular cytokines expression. This observation suggests that excessive pro-inflammatory cytokine expression in NK cells in RPL and implantation failures may be exerted through the NCRs or interruption of signal transduction processes. (Source: American Journal of Reproductive Immunology)
Source: American Journal of Reproductive Immunology - October 10, 2009 Category: Allergy & Immunology Authors: Atsushi Fukui, Evangelos Ntrivalas, Rie Fukuhara, Shunsaku Fujii, Hideki Mizunuma, Alice Gilman-Sachs, Kenneth Beaman, Joanne Kwak-Kim Source Type: journals

History of Incidence of Autoimmune and Oncological Diseases in Identical Female Twinsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion Association between autoimmune disease and gynecological cancer (or praecancerosis) is major risk than without immunology deviation. Twin A is periodically gynecologically observed. (Source: American Journal of Reproductive Immunology)
Source: American Journal of Reproductive Immunology - October 10, 2009 Category: Allergy & Immunology Authors: Z. Ulcova-Gallova, H. Brabcova, V. Kokes, L. Hradecky, Z. Novotny, Z. Rokyta Source Type: journals

Women with Pre-Eclampsia have an Altered NKG2A and NKG2C Receptor Expression on Peripheral Blood Natural Killer Cellsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
(Source: American Journal of Reproductive Immunology)
Source: American Journal of Reproductive Immunology - October 6, 2009 Category: Allergy & Immunology Authors: Nora Bachmayer, Ebba Sohlberg, Yvonne Sundström, Rangeen Rafik Hamad, Louise Berg, Katarina Bremme, Eva Sverremark-Ekström Tags: Erratum Source Type: journals

Multiple Cytokine Profile in Plasma and Amniotic Fluid in a Mouse Model of Pre-Term Laboremail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion These results suggest that stimulation of several pro-inflammatory cytokines occurs very early in the cascade of events and remains increased, whereas anti-inflammatory cytokines are either unchanged or decreased until the onset of delivery in an inflammation-induced mouse model of pre-term labor. (Source: American Journal of Reproductive Immunology)
Source: American Journal of Reproductive Immunology - October 6, 2009 Category: Allergy & Immunology Authors: Qing Yang, Yasser El-Sayed, Yael Rosenberg-Hasson, David L. Hirschberg, Nihar R. Nayak, James Schilling, Ashima Madan Tags: Original Articles Source Type: journals

Soluble Human Leukocyte Antigen-G Isoforms in Maternal Plasma in Early and Late Pregnancyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Problem Human Leukocyte Antigen (HLA)-G is a class Ib gene located in the human major histocompatibility complex (MHC). Several lines of investigation indicate that the HLA-G molecule is involved in the maternal acceptance of the semi-allogenic fetus during pregnancy and in the development of tolerance. Expression of soluble HLA-G (sHLA-G) is positively correlated with successful in vitro fertilization (IVF) treatments, and aberrant expression of HLA-G in certain complications of pregnancy, such as pre-eclampsia and spontaneous abortion, has been reported. The main purpose of this study was to investigate the levels of dif...
Source: American Journal of Reproductive Immunology - October 6, 2009 Category: Allergy & Immunology Authors: Roberta Rizzo, Anita Sylvest Andersen, Michael Rud Lassen, Helle Christina Sørensen, Thomas Bergholt, Margit Hørup Larsen, Loredana Melchiorri, Marina Stignani, Olavio R. Baricordi, Thomas Vauvert F. Hviid Tags: Original Articles Source Type: journals

Live Birth Rate According to Maternal Age and Previous Number of Recurrent Miscarriagesemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion The information concerning the live birth rate can be given to each patient before subsequent pregnancy. (Source: American Journal of Reproductive Immunology)
Source: American Journal of Reproductive Immunology - October 6, 2009 Category: Allergy & Immunology Authors: Mayumi Sugiura-Ogasawara, Yasuhiko Ozaki, Tamao Kitaori, Nobuhiro Suzumori, Shintaro Obayashi, Sadao Suzuki Tags: Original Articles Source Type: journals

An Interleukin-23 Binding Protein in Mid-Trimester Amniotic Fluidemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion Interleukin-23 and IL-12 share a common p40 subunit and no inhibition of IL-12 was apparent. It appeared that a component of mid-trimester amniotic fluid specifically interacts with the p19 subunit unique to IL-23. Mid-trimester amniotic fluid reactivity with IL-23 may be a mechanism to limit intra-amniotic neutrophil-derived inflammation. (Source: American Journal of Reproductive Immunology)
Source: American Journal of Reproductive Immunology - October 6, 2009 Category: Allergy & Immunology Authors: Catherine Herway, Ann Marie Bongiovanni, Daniel Skupski, Steven S. Witkin Tags: Original Articles Source Type: journals

A High Dose of Intravenous Immunoglobulin Increases CD94 Expression on Natural Killer Cells in Women with Recurrent Spontaneous Abortionemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion Mechanisms of possible efficacy of HIVIg therapy for RSA may include enhancement of CD94 expression and subsequent suppression of NK cell cytotoxicity. (Source: American Journal of Reproductive Immunology)
Source: American Journal of Reproductive Immunology - October 6, 2009 Category: Allergy & Immunology Authors: Shigeki Shimada, Masamitsu Takeda, Jun Nishihira, Masanori Kaneuchi, Noriaki Sakuragi, Hisanori Minakami, Hideto Yamada Tags: Original Articles Source Type: journals

Pre-Eclampsia, Placental Abruption and Increased Risk of Atopic Sensitization in Male Adolescent Offspringemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion Maternal PE and PA were associated with an increased risk of severe atopy, especially in male adolescent offspring. (Source: American Journal of Reproductive Immunology)
Source: American Journal of Reproductive Immunology - October 6, 2009 Category: Allergy & Immunology Authors: Leea Keski-Nisula, Seppo Heinonen, Sami Remes, Juha Pekkanen Tags: Original Articles Source Type: journals

PD-1 but not CTLA-4 Blockage Abrogates the Protective Effect of Regulatory T Cells in a Pregnancy Murine Modelemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion Our data suggest PD-1 as an important mediator in Treg-induced fetal protection in the CBA/J × DBA/2J murine model. (Source: American Journal of Reproductive Immunology)
Source: American Journal of Reproductive Immunology - October 6, 2009 Category: Allergy & Immunology Authors: Paul Ojiambo Wafula, Ana Teles, Anne Schumacher, Kerstin Pohl, Hideo Yagita, Hans-Dieter Volk, Ana Claudia Zenclussen Tags: Original Articles Source Type: journals

The Role of Cytokine Expression in Different Subgroups of Subfertile Menemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion Our study confirms that cytokines rarely act in isolation, but rather in a network of other cytokines and may affect sperm function directly or indirectly. The presence of increased levels of cytokines in the obstructed azoospermic group suggests that the cytokines may not originate from the testis. (Source: American Journal of Reproductive Immunology)
Source: American Journal of Reproductive Immunology - October 6, 2009 Category: Allergy & Immunology Authors: Srividya Seshadri, Michelle Bates, Gill Vince, D. I. Lewis Jones Tags: Original Articles Source Type: journals

Maternal Circulating TNF-α Levels are Highly Correlated with IL-10 Levels, but not IL-6 and IL-8 Levels, in Women with Pre-Eclampsiaemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion The correlation patterns of TNF-[alpha] with IL-10 and TNF-[alpha] with IL-6 and IL-8 suggest disparity in functional regulations between these cytokines in maternal circulation in PE. (Source: American Journal of Reproductive Immunology)
Source: American Journal of Reproductive Immunology - August 24, 2009 Category: Allergy & Immunology Authors: David F. Lewis, Bernard J. Canzoneri, Yuping Wang Source Type: journals

Serum IL-6 Level May Have Role in the Pathophysiology of Unexplained Infertilityemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion Significant difference in serum IL-6 levels between unexplained infertile and fertile women suggests that this cytokine may be involved in pathophysiology of unexplained infertility. (Source: American Journal of Reproductive Immunology)
Source: American Journal of Reproductive Immunology - August 23, 2009 Category: Allergy & Immunology Authors: Bulent Demir, Suleyman Guven, Emine Seda Guvendag Guven, Yildiz Atamer, Talip Gul Source Type: journals

Urocortin Increases IL-4 and IL-10 Secretion and Reverses LPS-induced TNF-α Release from Human Trophoblast Primary Cellsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion Urocortin stimulates IL-4 and IL-10 secretion and reverses LPS-induced TNF-[alpha] release from trophoblast cells through action on CRH-R2 receptors, suggesting that this peptide may play a possible role as an anti-inflammatory agent. (Source: American Journal of Reproductive Immunology)
Source: American Journal of Reproductive Immunology - August 23, 2009 Category: Allergy & Immunology Authors: Michela Torricelli, Chiara Voltolini, Enrrico Bloise, Giulia Biliotti, Alessia Giovannelli, Maria De Bonis, Alberto Imperatore, Felice Petraglia Source Type: journals

Endogenous Adenosine Down-Modulates Mid-Trimester IntraAmniotic Tumor Necrosis Factor-α Productionemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Problem To determine whether adenosine in amniotic fluid down-regulates pro-inflammatory cytokine production.Method of study Mid-trimester amniotic fluid from 21 women was incubated ex vivo in the presence or absence of human adenosine deaminase, the enzyme that irreversibly degrades adenosine. After 24 hr, supernatants were assayed by ELISA for tumor necrosis factor-[alpha] (TNF-[alpha]), interleukin (IL)-6, and IL-10. Clinical parameters were obtained after completion of laboratory testing.Results Inclusion of adenosine deaminase resulted in a median increase in TNF-[alpha] production from 0.9 to 7.3 pg/mL (P = 0.0014). ...
Source: American Journal of Reproductive Immunology - August 23, 2009 Category: Allergy & Immunology Authors: Uma Perni, Devrim Sezen, Ann Marie Bongiovanni, Iara M. Linhares, Daniel Skupski, Steven S. Witkin Source Type: journals

Human Serum Complement C3 and Factor H in the Syndrome of Hemolysis, Elevated Liver Enzymes, and Low Platelet Countemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion These findings did not support a major role of complement activation in the HELLP syndrome. In patients with HELLP, lower levels of FH are correlated with a reduced platelet count. (Source: American Journal of Reproductive Immunology)
Source: American Journal of Reproductive Immunology - August 23, 2009 Category: Allergy & Immunology Authors: Elif Ari, Yusuf Yilmaz, Ahmet Gul, Yesim Ozen Alahdab, Alla Eldeen Kedrah, Beyza Macunluoglu, Atakan Aydin, Hakki Arikan, Cetin Ozener Source Type: journals

Identification of Toll-Like Receptors in the Rat (Rattus norvegicus): Messenger RNA Expression in the Male Reproductive Tract Under Conditions of Androgen Variationemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion Tlr5, Tlr10, and Tlr11 are ubiquitously expressed in the rat. Tlrs seem to be expressed during male reproductive tract development and under conditions of androgen ablation, suggesting the preparedness of the male reproductive tract to detect an infection under all conditions of androgen status. (Source: American Journal of Reproductive Immunology)
Source: American Journal of Reproductive Immunology - August 23, 2009 Category: Allergy & Immunology Authors: Barnali Biswas, Ganapathy Narmadha, Mithilesh Choudhary, Frank S. French, Susan H. Hall, Suresh Yenugu Source Type: journals

A Retrospective Analysis of Fondaparinux Versus Enoxaparin Treatment in Women with Infertility or Pregnancy Lossemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion In patients with a history of miscarriage, infertility, and coagulant defects receiving immunotherapy, fondaparinux resulted in successful pregnancy outcomes comparable with enoxaparin therapy. Although no difference in outcome was observed in our analysis, a much larger study is required to achieve statistical power. (Source: American Journal of Reproductive Immunology)
Source: American Journal of Reproductive Immunology - August 23, 2009 Category: Allergy & Immunology Authors: Edward E. Winger, Jane L. Reed Source Type: journals

Gender Ratio Distortion in Abortuses and Live Births From Patients with Recurrent Spontaneous Abortionemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion These observations suggested that the aborted fetuses from RSA of unknown etiology, i.e. no chromosomal abnormality and no autoantibody, were preferentially female. (Source: American Journal of Reproductive Immunology)
Source: American Journal of Reproductive Immunology - August 11, 2009 Category: Allergy & Immunology Authors: Takashi Kano, Takahide Mori, Akinori Kimura Tags: Short Communication Source Type: journals

Plasma C3a-des-Arg Levels in Women with and without Endometriosisemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion We found no difference in C3a levels between women with and without endometriosis and did not confirm our hypothesis that plasma C3a levels can be used as diagnostic test for endometriosis. (Source: American Journal of Reproductive Immunology)
Source: American Journal of Reproductive Immunology - August 10, 2009 Category: Allergy & Immunology Authors: Amelie Fassbender, Thomas D'Hooghe, Attila Mihalyi, Cleophas Kyama, Peter Simsa, Bruce A. Lessey Tags: Original Articles Source Type: journals

Tumor Necrosis Factor-α-Associated Mechanisms Affecting the Embryonic Response to Cyclophosphamideemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion Our data implicate TNF-[alpha] to be involved in the protection of the embryo against CP teratogenicity, possibly via alteration in Bax, bcl-2 or p53 expression. (Source: American Journal of Reproductive Immunology)
Source: American Journal of Reproductive Immunology - August 10, 2009 Category: Allergy & Immunology Authors: Keren Mammon, Shoshana Savion, Hasida Orenstein, Amos Fein, Arkady Torchinsky, Vladimir Toder Tags: Original Articles Source Type: journals

Impact of Female Sex Hormones on the Maturation and Function of Human Dendritic Cellsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion Our findings suggest that the female sex hormones hCG and E2 inhibit the T-cell stimulatory capacity of DCs, which may help in preventing an allogenic T-cell response against the embryo. (Source: American Journal of Reproductive Immunology)
Source: American Journal of Reproductive Immunology - August 10, 2009 Category: Allergy & Immunology Authors: Sabine E. Segerer, Nora Müller, Jens van den Brandt, Michaela Kapp, Johannes Dietl, Holger M. Reichardt, Lorenz Rieger, Ulrike Kämmerer Tags: Original Articles Source Type: journals

Cytokine Array Comparisons of Plasma from Cycling Fertile Women on Cycle Day 5 and Ovulationemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion Circulating immuno-regulatory molecules fluctuate over the menstrual cycle in healthy women. The combination of differentially expressed molecules suggests roles in cyclical regulation of angiogenesis and immune cell trafficking. (Source: American Journal of Reproductive Immunology)
Source: American Journal of Reproductive Immunology - August 10, 2009 Category: Allergy & Immunology Authors: Kota Hatta, Michael J. Bilinski, J. Kimberly Haladyn, Jessica J. Roy, Julie Horrocks, Marianne J. van den Heuvel, Victor K. Han, B. Anne Croy Tags: Original Articles Source Type: journals

Women with Pre-Eclampsia Have an Altered NKG2A and NKG2C Receptor Expression on Peripheral Blood Natural Killer Cellsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions Our results suggest that the peripheral NK-cell pool is skewed in preeclampsia and possibly under the influence of monokines like interleukin (IL)-15 and IL-12. (Source: American Journal of Reproductive Immunology)
Source: American Journal of Reproductive Immunology - August 10, 2009 Category: Allergy & Immunology Authors: Nora Bachmayer, Ebba Sohlberg, Yvonne Sundström, Rangeen Rafik Hamad, Louise Berg, Katarina Bremme, Eva Sverremark-Ekström Tags: Original Articles Source Type: journals

H3N2 Influenza A Virus Replicates in Immortalized Human First Trimester Trophoblast Cell Lines and Induces Their Rapid Apoptosisemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion We revealed replication of low pathogenic influenza virus in the first trimester trophoblast cell lines. Placental damages are likely to be induced by direct cytopathic effects of influenza virus and subsequent apoptosis rather than down regulation of HLA-G expression and subsequent rejection by maternal immune system. (Source: American Journal of Reproductive Immunology)
Source: American Journal of Reproductive Immunology - August 10, 2009 Category: Allergy & Immunology Authors: Quang Duy Trinh, Yasuyuki Izumi, Shihoko Komine-Aizawa, Toshikatsu Shibata, Yoshitaka Shimotai, Kazumichi Kuroda, Masashi Mizuguchi, Hiroshi Ushijima, Gil Mor, Satoshi Hayakawa Tags: Original Articles Source Type: journals

Effects of Peritoneal Fluid from Endometriosis Patients on Interferon-γ-Induced Protein-10 (CXCL10) and Interleukin-8 (CXCL8) Released by Neutrophils and CD4+ T Cellsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion These findings suggest that neutrophils and T cells release differential levels of IP-10 and IL-8 in response to stimulation with ePF, and that these cells are a major source of IP-10 in the PF of endometriosis patients. (Source: American Journal of Reproductive Immunology)
Source: American Journal of Reproductive Immunology - August 10, 2009 Category: Allergy & Immunology Authors: Ji-Yeon Kim, Dong-Hyung Lee, Jong-Kil Joo, Jun-O Jin, Ji-Won Wang, Young-Seoub Hong, Jong-Young Kwak, Kyu-Sup Lee Tags: Original Articles Source Type: journals

Comparison of Serum Markers for Thrombophilia and Autoimmune Disease in Reproductive Age Women with and without False Positive Rapid Plasma Reagin Testsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion These results suggest that the RPR test might be used to identify a subset of women who warrant further testing for autoimmune and/or thromboembolic disease. (Source: American Journal of Reproductive Immunology)
Source: American Journal of Reproductive Immunology - July 9, 2009 Category: Allergy & Immunology Authors: Yael Swica, Carolyn Westhoff Tags: Short Communication Source Type: journals

Timed Sexual Intercourse Facilitates the Recruitment of Uterine CD56bright Natural Killer Cells in Women with Infertilityemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion It is suggested that seminal plasma participates in the recruitment of CD56bright NK cells into endometrium. (Source: American Journal of Reproductive Immunology)
Source: American Journal of Reproductive Immunology - July 8, 2009 Category: Allergy & Immunology Authors: Hidetaka Kimura, Atsushi Fukui, Shunsaku Fujii, Eiji Yamaguchi, Goichiro Kasai, Hideki Mizunuma Tags: Original Articles Source Type: journals

Uterine Leiomyoma is Associated with a Polymorphism in the Interleukin 1-β Geneemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Problem To investigate whether polymorphisms in the interleukin-1[beta] (IL-1[beta]) gene are associated with uterine leiomyoma.Method of study Case[ndash]control study in a collective of 131 patients and 280 controls. Genotyping of the IL-1[beta]-511 and IL-1[beta]-3954 polymorphism was performed by PCR amplification and subsequent RFLP analysis.Results A significant difference in the allele frequencies of the IL-1[beta]-511 C (Source: American Journal of Reproductive Immunology)
Source: American Journal of Reproductive Immunology - July 8, 2009 Category: Allergy & Immunology Authors: Detlef Pietrowski, Roberta Thewes, Michael Sator, Dominik Denschlag, Christoph Keck, Clemens Tempfer Tags: Original Articles Source Type: journals

Antiphospholipid Antibodies Induce a Pro-Inflammatory Response in First Trimester Trophoblast Via the TLR4/MyD88 Pathwayemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion These findings demonstrate that aPL triggers a placental inflammatory response via the TLR-4/MyD88 pathway, which in turn compromises trophoblast survival. Thus, the TLR-4/MyD88 pathway may provide a new therapeutic target to improve pregnancy outcome in antiphospholipid syndrome patients. (Source: American Journal of Reproductive Immunology)
Source: American Journal of Reproductive Immunology - July 8, 2009 Category: Allergy & Immunology Authors: Melissa J. Mulla, Jan J. Brosens, Larry W. Chamley, Ian Giles, Charis Pericleous, Anisur Rahman, Shawna K. Joyce, Britta Panda, Michael J. Paidas, Vikki M. Abrahams Tags: Original Articles Source Type: journals

Expression of Autotaxin, an Ectoenzyme that Produces Lysophosphatidic Acid, in Human Placentaemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion These findings suggest that trophoblasts might produce ATX and its bioactive resultant substance, LPA, paralleled with gestational weeks. (Source: American Journal of Reproductive Immunology)
Source: American Journal of Reproductive Immunology - July 8, 2009 Category: Allergy & Immunology Authors: Yuki Iwasawa, Tomoyuki Fujii, Takeshi Nagamatsu, Kei Kawana, Shinichi Okudaira, Shiho Miura, Junko Matsumoto, Ayako Tomio, Hironobu Hyodo, Takahiro Yamashita, Katsutoshi Oda, Shiro Kozuma, Junken Aoki, Yutaka Yatomi, Yuji Taketani Tags: Original Articles Source Type: journals

Epigenetics in the Placentaemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Epigenetics is focused on understanding the control of gene expression beyond what is encoded in the sequence of DNA. Central to growing interest in the field is the hope that more can be learned about the epigenetic regulatory mechanisms underlying processes of human development and disease. Researchers have begun to examine epigenetic alterations [ndash] such as changes in promoter DNA methylation, genomic imprinting, and expression of miRNA [ndash] to learn more about epigenetic regulation in the placenta, an organ whose proper development and function are crucial to the health, growth, and survival of the developing fe...
Source: American Journal of Reproductive Immunology - July 8, 2009 Category: Allergy & Immunology Authors: Matthew A. Maccani, Carmen J. Marsit Tags: Review Article Source Type: journals

Toll-Like Receptors, Inflammation and Tumor in the Human Female Reproductive Tractemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract Toll-like receptors are an important family of pattern recognition receptors. They recognize microbial conserved components and trigger protective responses to the invading pathogens, which constitute a major part of the innate immune system. Toll-like receptors are mainly expressed in immune cells. The current evidences demonstrate that Toll-like receptors are present in some epithelial cells and epithelium derived tumor cells. The expression of Toll-like receptors in these cells is related to infection and inflammation, and tumor progression as well. Genital mucosal epithelium is the first line in defense of mic...
Source: American Journal of Reproductive Immunology - June 11, 2009 Category: Allergy & Immunology Authors: Li Yu, Liantang Wang, Shangwu Chen Tags: Review Articles Source Type: journals

CCL20/MIP3α is a Novel Anti-HIV-1 Molecule of the Human Female Reproductive Tractemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion This study demonstrates that CCL20/MIP3[alpha] is an important endogenous anti-HIV-1 microbicide of the female reproductive tract. (Source: American Journal of Reproductive Immunology)
Source: American Journal of Reproductive Immunology - June 9, 2009 Category: Allergy & Immunology Authors: Mimi Ghosh, Zheng Shen, Todd M. Schaefer, John V. Fahey, Phalguni Gupta, Charles R. Wira Tags: Original Articles Source Type: journals

The Role of IL-6, IL-10, TNF-α and its Receptors TNFR1 and TNFR2 in the Local Regulatory System of Normal and Impaired Human Spermatogenesisemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion The results obtained indicate that changes in activities of intra-testicular cytokines may promote different distinct pathologies such as testicular cancer or infertility. (Source: American Journal of Reproductive Immunology)
Source: American Journal of Reproductive Immunology - June 9, 2009 Category: Allergy & Immunology Authors: Małgorzata Białas, Dorota Fiszer, Natalia Rozwadowska, Włodzimierz Kosicki, Piotr Jedrzejczak, Maciej Kurpisz Tags: Original Articles Source Type: journals

Calcineurin/NFAT Pathway: A Novel Regulator of Parturitionemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion Our findings suggested that the calcineurin/NFAT pathway might play a substantial role in initiation of labor. (Source: American Journal of Reproductive Immunology)
Source: American Journal of Reproductive Immunology - June 9, 2009 Category: Allergy & Immunology Authors: Chisa Tabata, Kazuhide Ogita, Keisuke Sato, Hitomi Nakamura, Zhang Qing, Hidenori Negoro, Keiichi Kumasawa, Kumiko Temma-Asano, Tateki Tsutsui, Katsuhiko Nishimori, Tadashi Kimura Tags: Original Articles Source Type: journals