Fibrinogen concentrate vs. fresh frozen plasma for the management of coagulopathy during thoraco ‐abdominal aortic aneurysm surgery: a pilot randomised controlled trial
SummaryMajor vascular surgery is frequently associated with significant blood loss and coagulopathy. Existing evidence suggests hypofibrinogenaemia develops earlier than other haemostatic deficiencies during major blood loss. The purpose of this study was to assess whether the use of an infusion of fibrinogen concentrate to prevent and treat hypofibrinogenaemia during surgery resulted in satisfactory haemostasis, removing or reducing the need for blood component transfusion. Twenty patients undergoing elective extent ‐4 thoraco‐abdominal aortic aneurysm repair were randomly allocated to receive either fresh frozen plas...
Source: Anaesthesia - November 23, 2018 Category: Anesthesiology Authors: G. A. Morrison, J. Koch, M. Royds, D. McGee, R. T. A. Chalmers, J. Anderson, A. F. Nimmo Tags: Original Article Source Type: research

Fibreoptic ‐guided tracheal intubation through i‐gel® and LMA® ProtectorTM supraglottic airway devices ‐ a randomised comparison
This study demonstrates that the LMA Protector supraglottic airway device is comparable to the i‐gel supraglottic airway device as a conduit for fibreoptic‐guided tracheal intubation. (Source: Anaesthesia)
Source: Anaesthesia - November 22, 2018 Category: Anesthesiology Authors: C. Mendonca, C. C. Tourville, H. Jefferson, A. Nowicka, M. Patteril, V. Athanassoglou Tags: Original Article Source Type: research

The association between attention deficit hyperactivity disorder and general anaesthesia ‐ a narrative review
SummaryAttention deficit hyperactivity disorder is a chronic neurodevelopmental disorder, manifesting primarily as attention deficit, hyperactivity and impulsive behaviour. General anaesthetics can be neurotoxic, affecting neuronal differentiation and synaptogenesis, which can lead to abnormalities of cognition, learning and behaviour. We hypothesise that exposure of the immature brain to general anaesthetics predisposes to the development of attention deficit hyperactivity disorder. In this review, we summarise clinical and animal studies that relate attention deficit hyperactivity disorder to general anaesthesia, by acti...
Source: Anaesthesia - November 22, 2018 Category: Anesthesiology Authors: L. Xu, Y. Hu, L. Huang, Y. Liu, B. Wang, L. Xie, Z. Hu Tags: Review Article Source Type: research

Airway management research: a systematic review
SummaryRecent controversy regarding the ethics of conducting airway research in patients led to disagreements concerning the value and frequency of manikin ‐based investigation. However, no formal examination of the methodology of airway research has been undertaken. We, therefore, performed a systematic bibliometric review of airway management research to describe the conduct, quantify the subjects (patient vs. manikin vs. other), assess the reporte d outcomes and map global trends. We retrieved 1505 relevant studies published between 2006 and 2017, together recruiting 359,648 subjects, of which 341,233 were patients, t...
Source: Anaesthesia - November 20, 2018 Category: Anesthesiology Authors: I. Ahmad, D. N. Onwochei, S. Muldoon, O. Keane, K. El ‐Boghdadly Tags: Review Article Source Type: research

Identifying the optimal regional predictor of right ventricular global function: a high ‐resolution three‐dimensional cardiac magnetic resonance study
SummaryRight ventricular (RV) function has prognostic value in acute, chronic and peri ‐operative disease, although the complex RV contractile pattern makes rapid assessment difficult. Several two‐dimensional (2D) regional measures estimate RV function, however the optimal measure is not known. High‐resolution three‐dimensional (3D) cardiac magnetic resonance cine imaging was acquired in 300 healthy volunteers and a computational model of RV motion created. Points where regional function was significantly associated with global function were identified and a 2D, optimised single‐point marker (SPM‐O) of global f...
Source: Anaesthesia - November 14, 2018 Category: Anesthesiology Authors: T. J. W. Dawes, A. de Marvao, W. Shi, D. Rueckert, S. A. Cook, D. P. O'Regan Tags: Original Article Source Type: research

Assessment of haemoglobin measurement by several methods – blood gas analyser, capillary and venous HemoCue®, non‐invasive spectrophotometry and laboratory assay – in term and preterm infants
This study compared alternative blood ‐sparing and non‐invasive methods of haemoglobin concentration measurement with the gold standard. Haemoglobin concentrations were measured using a laboratory haematology analyser (reference method), blood gas analyser, HemoCue® using venous and capillary blood samples and a newly developed non ‐invasive sensor for neonates< 3 kg. A total of 63 measurements were performed. Body weight (2190 (1820 –2520 [967–4450]) g) and haemoglobin concentration (12.3 (10.6–15.2 [8.2–20.5]) g.dl−1) varied widely. Bias/limits of agreement between the alternative methods and referenc...
Source: Anaesthesia - November 14, 2018 Category: Anesthesiology Authors: E. Wittenmeier, L. Lesmeister, N. Pirlich, F. Dette, I. Schmidtmann, E. Mildenberger Tags: Original Article Source Type: research

Correction
Anaesthesia, Volume 73, Issue 12, Page 1567-1567, December 2018. (Source: Anaesthesia)
Source: Anaesthesia - November 9, 2018 Category: Anesthesiology Tags: Correction Source Type: research

Issue Information – Editorial Board
Anaesthesia, Volume 73, Issue 12, Page 1451-1451, December 2018. (Source: Anaesthesia)
Source: Anaesthesia - November 9, 2018 Category: Anesthesiology Tags: Issue Information Source Type: research

Additional surgical site marks: a reply
Anaesthesia, Volume 73, Issue 12, Page 1579-1579, December 2018. (Source: Anaesthesia)
Source: Anaesthesia - November 9, 2018 Category: Anesthesiology Authors: J. J. Pandit, T. Meek Tags: Correspondence Source Type: research

Association of Anaesthetists guidelines on cell salvage: a reply
Anaesthesia, Volume 73, Issue 12, Page 1577-1577, December 2018. (Source: Anaesthesia)
Source: Anaesthesia - November 9, 2018 Category: Anesthesiology Authors: A. A. Klein, E. Evans Tags: Correspondence Source Type: research

Postoperative laryngeal morbidity using the McGRATH ™ MAC videolaryngoscope: a reply
Anaesthesia, Volume 73, Issue 12, Page 1569-1569, December 2018. (Source: Anaesthesia)
Source: Anaesthesia - November 9, 2018 Category: Anesthesiology Authors: T. Nakanishi, M. Yoshimura, S. Sakamoto, T. Toriumi Tags: Correspondence Source Type: research

Experience in awake fibreoptic intubation: a reply
Anaesthesia, Volume 73, Issue 12, Page 1571-1571, December 2018. (Source: Anaesthesia)
Source: Anaesthesia - November 9, 2018 Category: Anesthesiology Authors: K. El ‐Boghdadly, D. Onwochei, J. Cuddihy, I. Ahmad Tags: Correspondence Source Type: research

Experience in awake fibreoptic intubation
Anaesthesia, Volume 73, Issue 12, Page 1570-1570, December 2018. (Source: Anaesthesia)
Source: Anaesthesia - November 9, 2018 Category: Anesthesiology Authors: M. S. F. Chong, C. Oti Tags: Correspondence Source Type: research

Association of Anaesthetists recommendations for cell salvage in obstetric anaesthesia
Anaesthesia, Volume 73, Issue 12, Page 1575-1576, December 2018. (Source: Anaesthesia)
Source: Anaesthesia - November 9, 2018 Category: Anesthesiology Authors: A. Chakladar, V. Fludder, A. Sugavanam Tags: Correspondence Source Type: research

Additional surgical site marks
Anaesthesia, Volume 73, Issue 12, Page 1578-1578, December 2018. (Source: Anaesthesia)
Source: Anaesthesia - November 9, 2018 Category: Anesthesiology Authors: D. Buckley Tags: Correspondence Source Type: research