Differential Susceptibility to Propofol and Ketamine in Primary Cultures of Young and Senesced Astrocytes
In this study, we examined the survival and viability of both young and senescent astrocytes in culture after adding propofol and ketamine to the media at varying strengths. Oxidative stimulus was applied to commercially available fetal cell lines of human astrocytes in vitro to induce morphological changes in cellular senescence. Our results indicate that propofol reduces the survival of young astrocytes as compared to controls, as well as to ketamine. These effects were seen in comparisons of total cell count and at both high and low dose concentrations. High doses of propofol also significantly reduced cell viability co...
Source: Anesthesiology Research and Practice - April 18, 2024 Category: Anesthesiology Authors: Liang Huang Ferit Tuzer Abigail Murtha Michael Green Claudio Torres Henry Liu Shadi Malaeb Source Type: research

Effects of Preoperative Oral Carbohydrate on Perioperative Maternal Outcomes Undergoing Cesarean Section: A Systematic Review and Meta-Analysis
CONCLUSION: Preoperative oral CHO during cesarean section alleviates thirst and hunger, shortens the time of postoperative flatus, and reduces HOMA-IR. However, the available evidence is insufficient to reach a clear consensus on the benefits or harms of preoperative oral CHO during cesarean section. Therefore, it is premature to make a definitive recommendation for or against its routine use.PMID:38586152 | PMC:PMC10999288 | DOI:10.1155/2024/4660422 (Source: Anesthesiology Research and Practice)
Source: Anesthesiology Research and Practice - April 8, 2024 Category: Anesthesiology Authors: Haibin Shi Caihong Zheng Bin Zhu Source Type: research

Erector Spinae Plane Block versus Quadratus Lumborum Block for Postoperative Analgesia after Laparoscopic Resection of Colorectal Cancer: A Prospective Randomized Study
CONCLUSION: The analgesic efficacy of ESPB was better when compared to TQLB in terms of time to rescue analgesia and overall opioid consumption during the first 24 hours. This study was registered at ClinicalTrials.gov on 10/10/2022 (registration number: NCT05574283).PMID:38529324 | PMC:PMC10963107 | DOI:10.1155/2024/6200915 (Source: Anesthesiology Research and Practice)
Source: Anesthesiology Research and Practice - March 26, 2024 Category: Anesthesiology Authors: Dina Mahmoud Fakhry Hatem ElMoutaz Mahmoud Dina Yehia Kassim Hebatallah NegmEldeen AbdElAzeem Source Type: research