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65 records returned

Changes in bite force, masticatory muscle thickness, and facial morphology between primary and mixed dentition in preschool children with normal occlusion.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
The study of stomatognathic system development can provide useful data for recognition of deviations from normality. Thus, a longitudinal examination of 14 children with normal occlusion from primary (stage I, mean age 59.21+/-8.40 months) to early mixed dentition (stage II, 77.57+/-5.92) was performed. Bite force was measured with a pressurized tube and correlated with ultrasonographic masseter and anterior portion of temporalis muscle thicknesses (at rest and maximal intercuspation), facial dimensions, age, and body mass index (BMI). Facial dimensions were assessed by standardized frontal photographs as follows: ante...
Source: Annals of Anatomy - November 4, 2009 Category: Anatomy Authors: Castelo PM, Pereira LJ, Bonjardim LR, Gavião MB Tags: Ann Anat Source Type: journals

The precision of four commonly used surgical landmarks for locating the facial nerve in anterograde parotidectomy in humans.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
In addition to using intra-operative facial nerve monitoring in helping to locate the position of the facial nerve in anterograde parotidectomy, numerous soft tissue and bony landmarks have been proposed to assist the surgeon in the early identification of this nerve. There is still dispute within the literature as to the most effective method, if any, of locating the nerve. The purpose of this study was to measure the distance (in twenty-six embalmed cadavers) from four of the most commonly used surgical landmarks to the main trunk of the facial nerve-the posterior belly of digastric muscle (PBDM), the tragal pointer ...
Source: Annals of Anatomy - October 31, 2009 Category: Anatomy Authors: Rea PM, McGarry G, Shaw-Dunn J Tags: Ann Anat Source Type: journals

Enhanced constriction of supplying arteries - A mechanism of femoral head Necrosis in Wistar rats?email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
This study showed that vasoconstriction of the femoral artery in WKY rats was stronger than that of SHR rats. This may be a pathomechanical factor in femoral head necrosis of WKY rats. PMID: 19880298 [PubMed - as supplied by publisher] (Source: Annals of Anatomy)
Source: Annals of Anatomy - October 30, 2009 Category: Anatomy Authors: Drescher W, Lohse J, Varoga D, Buschmann C, Liebs T, Herdegen T, Hassenpflug J, Pufe T Tags: Ann Anat Source Type: journals

Differential cellular expression of FXYD1 (phospholemman) and FXYD2 (gamma subunit of Na, K-ATPase) in normal human tissues: A study using high density human tissue microarrays.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
This study reveals, in human tissues, the specific expression of FXYD proteins, which may associate with Na, K-ATPase in selected cell types and modulate its catalytic properties. PMID: 19879113 [PubMed - as supplied by publisher] (Source: Annals of Anatomy)
Source: Annals of Anatomy - October 7, 2009 Category: Anatomy Authors: Floyd RV, Wray S, Martín-Vasallo P, Mobasheri A Tags: Ann Anat Source Type: journals

'Last-minute' donations influence actuarial prediction in an anatomical body donation program.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
CONCLUSIONS: The present study provides the first method to reliably model the number of incoming deceased donors of a body donation program for 5 years based on actuarial predictions, and to orchestrate these numbers by partial donor registration stops. PMID: 19880299 [PubMed - as supplied by publisher] (Source: Annals of Anatomy)
Source: Annals of Anatomy - October 7, 2009 Category: Anatomy Authors: Wijbenga BS, Koning RH, Kooistra-Akse BJ, Bolt S, Kuks JB, van Zanten-Timmer G, Veening JG, Gerrits PO Tags: Ann Anat Source Type: journals

Some variations in lymphatic drainage of selected bronchopulmonary segments in human lungs.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Interest in the role of the pulmonary lymphatic system in the pathophysiology of pulmonary and systemic diseases induced us to carry out anatomical research on the lung lymphatic system in the Polish population. The aim of the study was to evaluate whether lymphatic vessels respect bronchopulmonary segment borders and to determine how often lymphatic vessels run to nodes of another lymphatic region. A block of organs comprising the lungs with the trachea, larynx and tongue, the heart and esophagus was removed from the cadavers at autopsy. The research involved 96 lungs (48 left and 48 right), which were taken from 31 m...
Source: Annals of Anatomy - September 10, 2009 Category: Anatomy Authors: Topol M, Masłoń A Tags: Ann Anat Source Type: journals

Structure and function of dendritic spines within the hippocampus.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Most excitatory input in the hippocampus impinges on dendritic spines. Therefore, the dendritic spines are likely to be of major importance for neural processing. The morphology of dendritic spines is very diverse and changes in spine size as well as in their density are thought to reflect changes in the strength of synaptic transmission. Thus, alterations in dendritic spine densities or shape are suspected to be morphological manifestations of psychopathological, pathophysiological, physiological and/or behavioural changes. However, in spite of a long history of research, the specific function of dendritic spines with...
Source: Annals of Anatomy - September 5, 2009 Category: Anatomy Authors: von Bohlen Und Halbach O Tags: Ann Anat Source Type: journals

Cataracta ossea - Ultrastructural and specimen analysis.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
CONCLUSIONS: Due to the small number of cases, the mechanisms and preconditions of osseous metaplasia of the lens are not understood in detail, but injury to the lens capsule and availability of blood supply are being discussed. Both were present in this case, in which the luxated lens ended up in the ciliary body region. The mechanism resembled enchondral ossification rather than intramembranous ossification, which is seen in osseous metaplasia of other intraocular structures. PMID: 19773150 [PubMed - as supplied by publisher] (Source: Annals of Anatomy)
Source: Annals of Anatomy - September 3, 2009 Category: Anatomy Authors: Koinzer S, Scharpenack P, Katzke H, Leuschner I, Roider J Tags: Ann Anat Source Type: journals

Observations on the synaptic ribbon morphology in retinas of two human subjects at autopsy.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Retinal photoreceptor and bipolar cell axon terminals possess synaptic ribbons (SR) that aid in the trafficking of synaptic vesicles at active zones. In rodents, besides SR, a number of other synaptic elements [e.g., synaptic spheres (SS)] are known to appear when exposed to altered ambient illumination. Here, we report changes of ribbon shape in photoreceptor and bipolar cell axon terminals in retinas of two persons at autopsy who suffered from brain hemorrhage. In both subjects, retinal hemorrhage was present in the outer and inner nuclear layers. SR were bent or swollen and transformed into SS. A count revealed that...
Source: Annals of Anatomy - September 3, 2009 Category: Anatomy Authors: Nag TC, Wadhwa S Tags: Ann Anat Source Type: journals

Insights into the nature of human testicular peritubular cells.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Human testicular peritubular cells are myofibroblast-like cells that surround the seminiferous tubules and are responsible for tubular contractility and sperm transport. In the last few years, several reports have augmented this simplified view, showing that peritubular cells are not only structural cells but also actively secrete paracrine mediators, thereby influencing the homeostasis of the testicular environment. This review is focussed on general aspects and functions of testicular peritubular cells, their potential role in male infertility and also on the recently described in vitro culture systems of human testi...
Source: Annals of Anatomy - August 27, 2009 Category: Anatomy Authors: Albrecht M Tags: Ann Anat Source Type: journals

Fascicles of the adult human Achilles tendon - An anatomical study.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
The Achilles or calcaneal tendon is the structural base for the biomechanical work of the ankle joint. The purpose of this study is to describe the internal structure of the human Achilles tendon. The anatomy of the Achilles tendon has been described in lower mammals in which it has three parts which can be dissected from its beginning to the insertion onto the calcaneus. The partial ruptures of each part suggest that the human Achilles tendon may also be composed of parts. The Achilles tendon is one of the most commonly torn tendons in the human body. Each segment of the Achilles tendon described by us can be ruptured...
Source: Annals of Anatomy - August 19, 2009 Category: Anatomy Authors: Szaro P, Witkowski G, Smigielski R, Krajewski P, Ciszek B Tags: Ann Anat Source Type: journals

Hertwig's epithelial root sheath cells do not transform into cementoblasts in rat molar cementogenesis.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
This study concludes that the epithelial-mesenchymal transformation does not occur in Hertwig's epithelial root sheath in rat acellular or cellular cementogenesis and that the dental follicle is the origin of cementoblasts, as has been proposed in the original hypothesis. PMID: 19716687 [PubMed - as supplied by publisher] (Source: Annals of Anatomy)
Source: Annals of Anatomy - August 12, 2009 Category: Anatomy Authors: Yamamoto T, Takahashi S Tags: Ann Anat Source Type: journals

Femoral head histology subsequent to ischemia, reperfusion, and steroid treatment.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
An episode of ischemia followed by reperfusion of the femoral head (FH) is thought to be a common pathway in the pathogenesis of femoral head necrosis (FHN). Femoral head histology was investigated after short-term high-dose steroid treatment and femoral head ischemia and reperfusion in a large animal model. Twenty-two pigs were randomized to receive methylprednisolone 20mg/day/kg bodyweight intamuscularly for 3 days followed by methylprednisolone 10mg/day/kg bodyweight for 11 days (n=11), whereas the control group (n=11) received no treatment. After 6h of unilateral hip-joint pressure increase to 250mmHg, the pressure...
Source: Annals of Anatomy - July 24, 2009 Category: Anatomy Authors: Schneider T, Cremer D, Becker C, Hansen ES, Bünger C, Drescher W Tags: Ann Anat Source Type: journals

Functional morphology of unguiculiform papillae of the reticular groove in the ruminant stomach.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
This study was aimed to elucidate the relation between the papillar morphology and its putative functions. The GG was obtained from adult bovine stomachs (n=10) and subdivided into (1) proximal, (2) middle, (3) distal portion of the reticular groove (RG) and (4) the area of the reticulo-omasal sphincter (ROS). The specimens were processed for scanning electron microscopy and stereomicroscopy to analyze the density, shape and location of the papillae. Whereas the proximal portion of the RG was characterized by small (1.5mm), conically shaped, smooth papillae, the middle portion exhibited larger papillae (4mm) with sharp bor...
Source: Annals of Anatomy - July 3, 2009 Category: Anatomy Authors: Teixeira AF, Kühnel W, Vives P, Wedel T Tags: Ann Anat Source Type: journals

Expression of glucose transporter isoforms and the insulin receptor during hamster preimplantation embryo development.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
During preimplantation development, embryos of many species are known to express up to five isoforms of the facilitative glucose transporter proteins (GLUT). Development of hamster blastocysts is inhibited by glucose. We therefore investigated GLUT isoform and insulin receptor (IR) expression in hamster preimplantation embryos cultured in glucose-free medium from the 8-cell stage onwards. We show that GLUT1, 3 and 8 mRNA are constitutively expressed from the 8-cell to the blastocyst stage. The IR is expressed from the morula stage onwards. Messenger RNA of the insulin-responsive GLUT4 was not detected at any stage. GLU...
Source: Annals of Anatomy - June 25, 2009 Category: Anatomy Authors: Tonack S, Ramin N, Garimella S, Rao R, Seshagiri PB, Fischer B, Navarrete Santos A Tags: Ann Anat Source Type: journals

Microanatomical and immunohistochemical study of the human radial nerve at the antecubital fossa.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
CONCLUSION: There is an increase in total nerve cross-sectional area of the radial nerve in elderly cases. There is no relationship of sympathetic content to age. Our study makes an attempt to build a normal data base for radial nerve which might be helpful during the application of diagnostic procedures. PMID: 19560325 [PubMed - as supplied by publisher] (Source: Annals of Anatomy)
Source: Annals of Anatomy - June 12, 2009 Category: Anatomy Authors: Chakravarthy Marx S, Kumar P, Dhalapathy S, Prasad K, Anitha Marx C Tags: Ann Anat Source Type: journals

Cryo-electron tomography in biology and medicine.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
During the last six decades electron microscopy (EM) has been essential to ultra-structural studies of the cell to understand the fundamentals of cellular morphology and processes underlying diseases. More recently, electron tomography (ET) has emerged as a novel approach able to provide three-dimensional (3D) information on cells and tissues at molecular level. Electron tomography is comparable to medical tomographic techniques like CAT, PET and MRI in the sense that it provides a 3D view of an object, yet it does so at a cellular scale and with nanometer resolution. Electron tomography has the unique ability to visua...
Source: Annals of Anatomy - June 8, 2009 Category: Anatomy Authors: Koning RI, Koster AJ Tags: Ann Anat Source Type: journals

Anatomical evaluation of oral microcirculation: Capillary characteristics associated with sex or age group.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
CONCLUSION: This study demonstrates the necessity of approaching the investigation of patient microcirculation in different ways depending on sex or age. PMID: 19541466 [PubMed - as supplied by publisher] (Source: Annals of Anatomy)
Source: Annals of Anatomy - June 8, 2009 Category: Anatomy Authors: Giuseppe Alessandro S, Antonino C, Messina P Tags: Ann Anat Source Type: journals

Anatomic variation of the celiac trunk with special reference to hepatic artery patterns.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Based on a large homogeneous sample from a Japanese population, anatomic variations in the celiac trunk (CT) and the hepatic artery were studied. Previously we analyzed the branching mode of the CT in 450 Japanese cadavers. In order to maximize the database on the CT and hepatic artery, we examined the anatomy of these arteries in 524 cadavers, a total of 974 cases. A total of 89.8% of cases showed the classical trifurcation of the CT. The typical normal pattern of the CT and the hepatic artery was confirmed in 66.6% and 72.4% of the cadavers, respectively. Variant left and right hepatic arteries were observed in 11.0%...
Source: Annals of Anatomy - June 5, 2009 Category: Anatomy Authors: Chen H, Yano R, Emura S, Shoumura S Tags: Ann Anat Source Type: journals

Activation and dedifferentiation of chondrocytes: Implications in cartilage injury and repair.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Cartilage injury remains a major challenge in orthopedic surgery due to the fact that articular cartilage has only a limited capacity for intrinsic healing. Cartilage impaction is followed by a post-traumatic inflammatory response. Chondrocytes and synoviocytes are activated to produce inflammatory mediators and degradative enzymes which can induce a progradient cartilage self-destruction finally leading to secondary osteoarthritis (OA). However, an anti-inflammatory compensatory response is also detectable in cartilage by up-regulation of anti-inflammatory cytokines, probably a temporary attempt by chondrocytes to res...
Source: Annals of Anatomy - June 5, 2009 Category: Anatomy Authors: Schulze-Tanzil G Tags: Ann Anat Source Type: journals

Acute traumatic death of a 17th century general based on examination of mummified remains found in Korea.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Recently, we examined one of the most perfectly preserved mummies of the Joseon Dynasty (1392-1910) ever found in Korea. The individual was an elderly man and a high-ranking general who had lived sometime during the 16th or 17th century in Korea. When computerized tomography (CT) radiographs were taken, a fracture line was observed on the left side of the mandible. A post-factum dissection also provided crucial clues to the cause of death. First of all, blood clots were still evident at the fracture site, indicating that the mandibular fracture had occurred just before death. Second, we also found feces exclusively in ...
Source: Annals of Anatomy - May 31, 2009 Category: Anatomy Authors: Lee IS, Lee EJ, Park JB, Baek SH, Oh CS, Lee SD, Kim YS, Bok GD, Hong JW, Lim DS, Shin MH, Seo M, Shin DH Tags: Ann Anat Source Type: journals

Experimental models of peripheral neuropathic pain based on traumatic nerve injuries - an anatomical perspective.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Peripheral neuropathic pain (PNP) frequently occurs as a consequence of nerve injury and may differ depending upon the type of insult and the individual patient. Progress in our knowledge of PNP induction mechanisms depends upon the utilization of appropriate experimental models in rodents based on various types of peripheral nerve lesions. In this review, we draw attention to current knowledge on basic cellular and molecular events in various experimental models used to induce the PNP symptoms. Spontaneous ectopic activity of axotomized and non-axotomized primary sensory neurons, the bodies of which are located in the...
Source: Annals of Anatomy - May 31, 2009 Category: Anatomy Authors: Klusáková I, Dubový P Tags: Ann Anat Source Type: journals

Age changes in the human oculomotor nerve - a stereological study.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
The oculomotor nerve (ON) provides motor innervation to the eyeball and exhibits alterations in various physiological and pathological conditions, which may result in abnormal ocular movement. Although the nerve has been studied in detail, very few data are available regarding its morphology and changes with aging. Hence, in the present investigation, the neural and connective tissue organizations of the pre-cavernous part of the ON were studied in order to provide sequential data regarding age-related morphological changes. Thirty-eight ON from cadavers aged from 40 post-natal days to 78 years were studied. Cross-sect...
Source: Annals of Anatomy - May 31, 2009 Category: Anatomy Authors: Sharma S, Ray B, Bhardwaj D, Dwivedi AK, Roy TS Tags: Ann Anat Source Type: journals

Ultrastructural analysis of the lamina cribrosa after radial optic neurotomy.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Radial optic neurotomy (RON) has been proposed for alleviation of the "scleral outlet compartment syndrome" at the level of the lamina cribrosa, which is thought to play a pathoetiologic role in central retinal vein occlusion (CRVO). The aim of this study has been to analyze the ultrastructural alterations of the lamina cribrosa after RON to gain new insights in the underlying pathomechanical factors. Fifteen donor eyes underwent a standardized open-sky-vitrectomy and RON after removal of the anterior eye segment for keratoplasty. Using a microvitreoretinal blade, a radial incision was performed on the nasal hemisphere...
Source: Annals of Anatomy - May 31, 2009 Category: Anatomy Authors: Hasselbach H, Thale A, Bunse A, Paulsen F, Roider J Tags: Ann Anat Source Type: journals

Electrical stimulation of paralyzed vibrissal muscles reduces endplate reinnervation and does not promote motor recovery after facial nerve repair in rats.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
The outcome of peripheral nerve injuries requiring surgical repair is poor. Recent work has suggested that electrical stimulation (ES) of denervated muscles could be beneficial. Here we tested whether ES has a positive influence on functional recovery after injury and surgical repair of the facial nerve. Outcomes at 2 months were compared to animals receiving sham stimulation (SS). Starting on the first day after end-to-end suture (facial-facial anastomosis), electrical stimulation (square 0.1ms pulses at 5Hz at an ex tempore established threshold amplitude of between 3.0 and 5.0V) was delivered to the vibrissal muscle...
Source: Annals of Anatomy - May 12, 2009 Category: Anatomy Authors: Sinis N, Horn F, Genchev B, Skouras E, Merkel D, Angelova SK, Kaidoglou K, Michael J, Pavlov S, Igelmund P, Schaller HE, Irintchev A, Dunlop SA, Angelov DN Tags: Ann Anat Source Type: journals

The sacrotuberous and the sacrospinous ligament - A virtual reconstruction.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Little is known about the morphometric properties of the sacrotuberous ligament (ST) and the sacrospinous ligament (SS). The influence of ligaments on pelvic stability and the extent of reconstruction in case of instability are controversially discussed. The ST and the SS of 55 human subjects fixed in alcohol solution and of four fresh cadavers were measured. Both ligaments were defined as geometric figures. The ST was a contorted bifrustum, while the SS was a contorted frustum, both with elliptic planes. In all cases investigated, the ST and the SS fibres were twisted. For men, the ST and the SS had a mean length of 6...
Source: Annals of Anatomy - May 2, 2009 Category: Anatomy Authors: Hammer N, Steinke H, Slowik V, Josten C, Stadler J, Böhme J, Spanel-Borowski K Tags: Ann Anat Source Type: journals

Quantitative research using computed tomographic scanning of beagle jaws for determination of safe zones for micro-screw implantation.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions. The present study provides a map of safe areas for the application of micro-screws in beagles. PMID: 19457649 [PubMed - as supplied by publisher] (Source: Annals of Anatomy)
Source: Annals of Anatomy - May 2, 2009 Category: Anatomy Authors: Zhao L, Xu Z, Yang Z, Wang J, Wei X, Tang T, Zhao Z Tags: Ann Anat Source Type: journals

Student learning preferences and the impact of a multimedia learning tool in the dissection course at the University of Munich.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
How do students use multimedia tools to support their learning during a gross anatomy dissection course? We investigated this question in the anatomic dissection course for first year medical students at the University of Munich (n=850) by giving all participating students access to an anatomical multimedia CD-ROM. The use of this multimedia learning tool was voluntary and it was not essential for the end-of-course examination. After the examination, two questionnaires (return rate first questionnaire n(1)=347, approximately 41%; return rate second questionnaire n(2)=644, approximately 76%) were given to the surveyed s...
Source: Annals of Anatomy - May 2, 2009 Category: Anatomy Authors: Adamczyk C, Holzer M, Putz R, Fischer MR Tags: Ann Anat Source Type: journals

Differentiation of activated monocytes into osteoclast-like cells on a hydroxyapatite substrate: An in vitro study.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
CONCLUSIONS: These studies were designed to test a model in which osteoclasts could be formed from HA-activated monocytes via positive feedback elicited by RANKL, allowing for identification of innovative targets for therapeutic approaches. PMID: 19447592 [PubMed - as supplied by publisher] (Source: Annals of Anatomy)
Source: Annals of Anatomy - April 23, 2009 Category: Anatomy Authors: Narducci P, Nicolin V Tags: Ann Anat Source Type: journals

Analysis of microcracks caused by drop shatter testing of porcine kidneys.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Although kidney trauma is a relatively common injury, its microscopic biomechanics are poorly understood. Experimental low-grade trauma in pig kidneys was studied using optical microscopy. We observed ruptures in the cortex as well as in the medulla. Both parts of the renal parenchyma were damaged, even in areas of the kidneys that were free of macroscopic cracks on the surface. To determine which constituents of the renal cortex and medulla, i.e. tubular parts of the nephron or the interstitial connective tissue, were less resistant to injury during the drop shatter test, we applied a simple stereological method to di...
Source: Annals of Anatomy - March 11, 2009 Category: Anatomy Authors: Tonar Z, Janáček J, Nedorost L, Grill R, Báča V, Záťura F Tags: Ann Anat Source Type: journals

Morphological evaluation of temporomandibular joint after open and closed treatment of type B diacapsular condylar fractures in sheep.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
The incidence of diacapsular fracture of the mandibular condyle (DFMC) has increased in recent years. However, the specific modality of treatment which would provide maximum benefit and good results for adult patients of DFMC has been controversial. To evaluate and compare morphological changes of temporomandibular joint (TMJ) after open and closed treatments for DFMC, a sheep model of a type B DFMC was created by osteotomy. Eight sheep models of type B DFMC were randomly divided into 2 groups to receive closed treatment (Group 1) and open reduction and internal fixation (ORIF, Group 2), respectively, and morphological...
Source: Annals of Anatomy - February 12, 2009 Category: Anatomy Authors: Meng FW, Hu KJ, Kong L, Zhao YT, Liu YP, Zhou SX Tags: Ann Anat Source Type: journals

Walther Flemming on histology in medicine 1878: A newly discovered letter to his father.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Histology is a child of the 19th century, and its status in medicine was long in doubt. Was "microscopic anatomy" to be viewed as a refinement of the traditional discipline or as a technically complex subject of doubtful practical value? This was one of the questions that faced the commission charged with reforming examinations in German medical schools in 1878. One of its members, Carl Friedrich Flemming [1799-1880], was able to refer this matter to an acknowledged expert, his son Walther Flemming, who was Professor of Anatomy and Histology at the University of Kiel. Walther's views are contained in a letter that was ...
Source: Annals of Anatomy - February 12, 2009 Category: Anatomy Authors: Hardy PA, Zacharias H Tags: Ann Anat Source Type: journals

Stereological evaluation of the volume and volume fraction of intracranial structures in magnetic resonance images of patients with Alzheimer's disease.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
In conclusion, the cerebral and cerebellar to TBV volume fractions can be important tools in determining brain atrophy and can be estimated by the stereological method. PMID: 19269145 [PubMed - as supplied by publisher] (Source: Annals of Anatomy)
Source: Annals of Anatomy - February 12, 2009 Category: Anatomy Authors: Bas O, Acer N, Mas N, Karabekir HS, Kusbeci OY, Sahin B Tags: Ann Anat Source Type: journals

A quantitative analysis of splint therapy of displaced temporomandibular joint disc.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
CONCLUSIONS: The evaluation of the Michigan splint therapy showed that it has no influence in the repositioning of the DD joints without reduction, but the DD joints with reduction have a limited positive effect. In both forms of these displacements, conditions for the elimination of the clinical symptoms are created. PMID: 19282162 [PubMed - as supplied by publisher] (Source: Annals of Anatomy)
Source: Annals of Anatomy - February 12, 2009 Category: Anatomy Authors: Badel T, Marotti M, Kern J, Laškarin M Tags: Ann Anat Source Type: journals

Evaluation of labial microvessels in Sjogren syndrome: A videocapillaroscopic study.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
CONCLUSION: Labial microcirculation alterations occur in SS patients. The study of the microcirculation in autoimmune pathology such as SS could provide new understanding on the dynamics of the pathology and could help to complete the diagnosis. PMID: 19269146 [PubMed - as supplied by publisher] (Source: Annals of Anatomy)
Source: Annals of Anatomy - February 11, 2009 Category: Anatomy Authors: Scardina GA, Ruggieri A, Messina P Tags: Ann Anat Source Type: journals

Cryopreparation of biological specimens for immunoelectron microscopy.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions drawn from ultrastructural data should always be based on the best possible technique of sample preparation. Cryofixation is the state-of-the-art method for ultrastructural preservation, but for unstable and anoxia sensitive tissues, a combination of chemical prefixation with HPF and freeze substitution might be a valuable compromise. PMID: 19264467 [PubMed - as supplied by publisher] (Source: Annals of Anatomy)
Source: Annals of Anatomy - January 20, 2009 Category: Anatomy Authors: Möbius W Tags: Ann Anat Source Type: journals

Long-term exposure to hypobaric hypoxia in rat affects femur cross-sectional geometry and bone tissue material properties.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
This study investigates the effect of chronic hypobaric hypoxia (simulated high altitude, SHA) on the biomechanics of rat femurs by mechanical tests of diaphyseal stiffness and strength and calculation of some indicators of bone material properties. Adult female rats were exposed to SHA (5500m, 23.5h/d for 60d=HX rats; NX=normoxic). This treatment induced reticulocytosis and polycythemia. Bone mineral content did not differ between NX and HX rats at the end of the study. To determine cortical bone mechanical properties, the right femur was assessed using a 3-point bending test. Endosteum and periosteum moved away from the ...
Source: Annals of Anatomy - January 20, 2009 Category: Anatomy Authors: Bozzini C, Olivera MI, Huygens P, Alippi RM, Bozzini CE Tags: Ann Anat Source Type: journals

Widespread thalamic and cerebellar degeneration in a patient with a complicated hereditary spastic paraplegia (HSP).email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
The hereditary spastic paraplegias (HSP) are a heterogeneous group of familial movement disorders sharing progressive spastic paraplegia as a common disease sign. In the present study, we performed the first pathoanatomical investigation of the central nervous degeneration of a female patient with a complicated HSP form who suffered from progressive spastic paraplegia, dysarthria, emotional symptoms, cognitive decline and a variety of additional neuropsychological deficits. This pathoanatomical investigation revealed in addition to loss of layer V Betz pyramidal cells in the primary motor cortex, widespread cerebellar ...
Source: Annals of Anatomy - January 20, 2009 Category: Anatomy Authors: Seidel K, De Vos R, Derksen L, Bauer P, Riess O, den Dunnen W, Deller T, Hageman G, Rüb U Tags: Ann Anat Source Type: journals

A review of recent methods for efficiently quantifying immunogold and other nanoparticles using TEM sections through cells, tissues and organs.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Detecting, localising and counting ultrasmall particles and nanoparticles in sub- and supra-cellular compartments are of considerable current interest in basic and applied research in biomedicine, bioscience and environmental science. For particles with sufficient contrast (e.g. colloidal gold, ferritin, heavy metal-based nanoparticles), visualization requires the high resolutions achievable by transmission electron microscopy (TEM). Moreover, if particles can be counted, their spatial distributions can be subjected to statistical evaluation. Whatever the level of structural organisation, particle distributions can be ...
Source: Annals of Anatomy - November 30, 2008 Category: Anatomy Authors: Mayhew TM, Mühlfeld C, Vanhecke D, Ochs M Tags: Ann Anat Source Type: journals

Orientation of the rotator cuff insertion facets on the humerus: Comparison between individuals with intact and torn rotator cuffs.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
The purpose of this work has been to compare the orientation of the rotator cuff insertions on the humerus between individuals with intact and torn rotator cuffs, respectively, to look for anatomical factors involved in the pathogenesis of rotator cuff tears. A total of 60 patients evaluated by arthro-computed tomography (CT) were divided into an intact rotator cuff group (31 patients) and a torn rotator cuff group (29 patients). The orientation angles of the lesser humeral tubercle facet and of the superior, middle and inferior facets of the greater humeral tubercle were measured in the sagittal plane between the hori...
Source: Annals of Anatomy - November 30, 2008 Category: Anatomy Authors: Le Corroller T, Aswad R, Pauly V, Champsaur P Tags: Ann Anat Source Type: journals

Soluble and membranous vascular endothelial growth factor receptor-1 in pregnancies complicated by pre-eclampsia.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Vascular endothelial growth factor receptor-1 (VEGFR-1) is essential for the normal development and function of the placenta. Defective placental vasculogenesis and trophoblast function may lead to pre-eclampsia, a pregnancy-specific syndrome of hypertension and proteinuria. In order to study the association of VEGFR-1 with the development of pre-eclampsia, a cross-sectional study was carried out to evaluate the concentration of soluble VEGFR-1 (sVEGFR-1) in 360 serum samples and to analyze the expression of membranous VEGFR-1 in 40 placental samples of normal and pre-eclamptic pregnant women. Serum and placental sampl...
Source: Annals of Anatomy - November 12, 2008 Category: Anatomy Authors: Tripathi R, Rath G, Jain A, Salhan S Tags: Ann Anat Source Type: journals

Bio-technologies for a glandular stem cell cardiomyopexy.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
The glandular stem cell cardiomyopexy should become a treatment option for end-stage heart failure. It combines an expected regenerative potential of transformed adult glandular stem cells into cardiomyocytes within the myocardium or onto the myocardium of the recipient and the potential of a hypercapillarized latissimus dorsi muscle (LDM) wrapped around the heart for stem cell nutrition and girdling. PMID: 18950997 [PubMed - as supplied by publisher] (Source: Annals of Anatomy)
Source: Annals of Anatomy - September 27, 2008 Category: Anatomy Authors: Guldner NW, Klapproth P, Schwarz PO, Hardel T, Rumpf PM, Kajahn J, Margaritoff P, Sievers HH, Grossherr M Tags: Ann Anat Source Type: journals

A study on the relationship between intraglandular arterial distribution and thyroid lobe shape: Implications for biotechnology of a bioartificial thyroid.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
We have recently hypothesized that structural and secretory components of the adult human thyroid gland maintain constant reciprocal and geometrical relationships, even if changes occur in the three-dimensional (3D) architecture of any of these elements. This means that thyroid morphology could be studied from the point of view of a 3D topology. As a consequence, we have investigated anatomical aspects that could support this assumption. In the present study, we show that the presence of a constant relationship can be demonstrated between the vascular arrangement of the gland, including the extension of intraglandular ...
Source: Annals of Anatomy - September 23, 2008 Category: Anatomy Authors: Toni R, Casa CD, Bodria M, Spaletta G, Vella R, Castorina S, Gatto A, Teti G, Falconi M, Rago T, Vitti P, Sgallari F Tags: Ann Anat Source Type: journals

Controlling alpha-SMA expression in adult human pancreatic stem cells by soluble factors.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
In the application of adult stem cells in regenerative medicine, it is indispensable to control stem cell behaviour in vitro. Since stem cells spontaneously differentiate into several cell types, it is mandatory to identify methods to enrich the desired cell types and concurrently block other differentiation pathways. More precisely, generation of a defined cell population is a key prerequisite for a therapeutic application of stem cells. Here we have demonstrated that it is possible to influence the differentiation of human pancreatic stem cells (hPSCs). During activation of mesodermal differentiation, the cytoskeleta...
Source: Annals of Anatomy - September 20, 2008 Category: Anatomy Authors: Petschnik AE, Ciba P, Kruse C, Danner S Tags: Ann Anat Source Type: journals

Insights into the transcriptional and chromatin regulation of mesenchymal stem cells in musculo-skeletal tissues.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Utilizing adult stem cells for regenerative medicine of skeletal tissues requires the development of molecular and biochemical tools that will allow isolation of these cells and direction of their differentiation towards a desired lineage and tissue formation. Stem cell commitment and fate decision into specialized functional cells involve coordinated activation and silencing of lineage-specific genes. Transcription factors and chromatin-remodeling proteins are key players in the control process of lineage commitment and differentiation during embryogenesis and adulthood. Transcription factors act in cooperation with c...
Source: Annals of Anatomy - September 10, 2008 Category: Anatomy Authors: Benayahu D, Shefer G, Shur I Tags: Ann Anat Source Type: journals

Mesenchymal stem cells as a potential pool for cartilage tissue engineering.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Osteoarthritis (OA) resulting from trauma, degenerative or age-related disease presents a major clinical challenge due to the limited repair capacity of articular cartilage. This poor self-repair capacity of osteochondral defects has resulted in the development of a wide variety of new treatment approaches. Although the use of chondrocytes in applications of cartilage tissue engineering is still prevalent, concerns associated with donor-site morbidity, cell de-differentiation and the limited lifespan of these cells have brought the use of mesenchymal stem cells (MSCs) to the forefront of such applications. Therefore, i...
Source: Annals of Anatomy - August 28, 2008 Category: Anatomy Authors: Csaki C, Schneider PR, Shakibaei M Tags: Ann Anat Source Type: journals

Magnetic resonance imaging of heterotaxis syndrome.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
We report on a 20-year-old young woman who presented to the emergency room with upper abdominal pain. On chest X-ray, dextrocardia was noted. Ultrasound was inconclusive. Barium studies demonstrated non-rotation of the intestine. Magnetic resonance imaging (MRI) of the abdomen confirmed heterotaxis with abnormal arrangement of abdominal organs and vasculature. This is the first radiographic description of LRA in MRI. It provides a unique contribution to the wide morphological variety of lateralization defects in a single examination within 15min and without the risks of ionizing radiation. In addition, a literature overvie...
Source: Annals of Anatomy - August 28, 2008 Category: Anatomy Authors: Stoeckelhuber BM, Eckey T, Buchholz M, Kapsimalakou S, Stoeckelhuber M Tags: Ann Anat Source Type: journals

Immunohistochemical study on the distribution of insulin-like growth factor-binding protein 4 in the central nervous system of SOD1(G93A) transgenic mice as an in vivo model of amyotrophic lateral sclerosis.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
This study, showing decreased IGFBP4 in different brain regions of SOD1(G93A) transgenic mice, may provide clues to understanding the differential susceptibility of neural structures in ALS, suggesting a role of IGFBP4 in an abnormality of cognitive and/or motor function in ALS. The mechanisms and functional implications of these decreases require elucidation. PMID: 18823765 [PubMed - as supplied by publisher] (Source: Annals of Anatomy)
Source: Annals of Anatomy - August 28, 2008 Category: Anatomy Authors: Kang DW, Chung YH, Lee JC, Bang JS, Kim D, Kim SS, Kim KY, Lee WB, Cha CI Tags: Ann Anat Source Type: journals

Marie-François Xavier Bichat (1771-1802) and his contributions to the foundations of pathological anatomy and modern medicine.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Marie-François Xavier Bichat (1771-1802) and his contributions to the foundations of pathological anatomy and modern medicine. Ann Anat. 2008 Aug 20; Authors: Shoja MM, Tubbs RS, Loukas M, Shokouhi G, Ardalan MR Marie-François Xavier Bichat (1771-1802) was a prominent French anatomist during a time of revolution and one of the founders of French scientific medicine. He conducted several experimental studies, which laid the foundation for modern physiology. Based on autopsy findings, Bichat introduced 21 tissues as the basic elements of organs. His name is carried on by several eponyms in anatomy and h...
Source: Annals of Anatomy - August 20, 2008 Category: Anatomy Authors: Shoja MM, Tubbs RS, Loukas M, Shokouhi G, Ardalan MR Tags: Ann Anat Source Type: journals

Prof. Dr. Sport.-Wiss. Dr. rer. nat. Horst Michna (1954-2007).email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Prof. Dr. Sport.-Wiss. Dr. rer. nat. Horst Michna (1954-2007). Ann Anat. 2008;190(2):97-102 Authors: Kühnel W PMID: 18672494 [PubMed - in process] (Source: Annals of Anatomy)
Source: Annals of Anatomy - August 2, 2008 Category: Anatomy Authors: Kühnel W Tags: Ann Anat Source Type: journals