PacBio Third-Generation Sequencing Reveals an < em > ABO < /em > Gene Promoter Mutation, c.-35_-18del, Leading to Weakened B Antigen Expression
Ann Lab Med. 2024 Apr 11. doi: 10.3343/alm.2024.0069. Online ahead of print.NO ABSTRACTPMID:38600024 | DOI:10.3343/alm.2024.0069 (Source: Annals of Laboratory Medicine)
Source: Annals of Laboratory Medicine - April 10, 2024 Category: Laboratory Medicine Authors: Lin-Nan Shao Yue-Xin Xia Yi-Cheng Yang Ning Li Chun-Xiang Li Shi-Hang Zhou Source Type: research

Comparison of Target- and IgG-Enrichment Strategies to Measure Adalimumab Concentrations in Human Plasma Using an Immunocapture-Liquid Chromatography-High-Resolution Mass Spectrometry Platform
Ann Lab Med. 2024 Apr 9. doi: 10.3343/alm.2023.0468. Online ahead of print.NO ABSTRACTPMID:38589211 | DOI:10.3343/alm.2023.0468 (Source: Annals of Laboratory Medicine)
Source: Annals of Laboratory Medicine - April 8, 2024 Category: Laboratory Medicine Authors: Xiaoliang Ding Shengxiong Zhu Linsheng Liu Xiaoxue Liu Kouzhu Zhu Liyan Miao Source Type: research

Integration of an MC-80 Digital Image Analyzer With an Automated BC-6800Plus Hematology Analyzer Enables Accurate Platelet Counting in Samples With EDTA-Induced Pseudothrombocytopenia
CONCLUSIONS: BC-6800Plus PLT-O measurement results are close to the actual values obtained by platelet deaggregation with PTCP samples. Integrating the BC-6800Plus with a digital imaging analyzer effectively improved the diagnosis of PTCP and reduced the requirement for additional laboratory procedures.PMID:38572537 | DOI:10.3343/alm.2023.0460 (Source: Annals of Laboratory Medicine)
Source: Annals of Laboratory Medicine - April 4, 2024 Category: Laboratory Medicine Authors: Min-Kyung So Jungwon Huh Seunghwan Kim Sholhui Park Source Type: research

Metformin Suppresses Both PD-L1 Expression in Cancer Cells and Cancer-Induced PD-1 Expression in Immune Cells to Promote Antitumor Immunity
CONCLUSIONS: Metformin blocks both PD-L1 and PD-1 within the tumor microenvironment. This study provided a mechanistic insight into the efficacy of metformin in improving immunotherapy in human cancer.PMID:38529546 | DOI:10.3343/alm.2023.0443 (Source: Annals of Laboratory Medicine)
Source: Annals of Laboratory Medicine - March 26, 2024 Category: Laboratory Medicine Authors: Su Hwan Park Juheon Lee Hye Jin Yun Seok-Ho Kim Jong-Ho Lee Source Type: research