Serum soluble TREM2 as a biomarker for incident dementia: the Hisayama Study
This article is protected by copyright. All rights reserved. (Source: Annals of Neurology)
Source: Annals of Neurology - November 28, 2018 Category: Neurology Authors: Tomoyuki Ohara, Jun Hata, Masashi Tanaka, Takanori Honda, Hajime Yamakage, Daigo Yoshida, Takayuki Inoue, Yoichiro Hirakawa, Toru Kusakabe, Mao Shibata, Tadashi Teraoka, Takanari Kitazono, Shigenobu Kanba, Noriko Satoh ‐Asahara, Toshiharu Tags: Research Article Source Type: research

Six ‐months assessment of a hand prosthesis with intraneural tactile feedback
This article is protected by copyright. All rights reserved (Source: Annals of Neurology)
Source: Annals of Neurology - November 25, 2018 Category: Neurology Authors: F.M. Petrini, G. Valle, I. Strauss, G. Granata, R. Di Iorio, E. D'Anna, P. Čvančara, M. Mueller, J. Carpaneto, F. Clemente, M. Controzzi, L. Bisoni, C. Carboni, M. Barbaro, F. Iodice, D. Andreu, A. Hiairrassary, J.L. Divoux, C. Ciprian Tags: Research Article Source Type: research

Correction: An extremely severe phenotype attributed to WDR81 nonsense mutations
Annals of Neurology, Volume 84, Issue 5, Page 796-796, November 2018. (Source: Annals of Neurology)
Source: Annals of Neurology - November 21, 2018 Category: Neurology Tags: Correction Source Type: research

Annals of Neurology: Volume 84, Number 5, November 2018
A photomicrograph of HeLa cells expressing amino acids 1 ‐149 of the protein KCTD7 with a mutation (L108M) seen in patients who have progressive myoclonic epilepsy (EPM3) also known as neuronal ceroid lipofuscinosis (CLN14). The mutant protein has an HA tag that has been stained with red fluorescence to localize the protein, revealing red filaments in t he nucleus and in the surrounding cytoplasm. Filament structures are altered by this L108M mutation in the BTB domain of KCTD7. The nucleus of each cell is stained blue. (See Metz et al., pageshttp://dx.doi.org/10.1002/ana.25351766 –780) (Source: Annals of Neurology)
Source: Annals of Neurology - November 21, 2018 Category: Neurology Tags: Cover Image Source Type: research

Issue Information
Annals of Neurology, Volume 84, Issue 5, Page i-vii, November 2018. (Source: Annals of Neurology)
Source: Annals of Neurology - November 21, 2018 Category: Neurology Tags: Issue Information Source Type: research

Final Results of the RHAPSODY trial: A multi ‐center, Phase 2 trial using a continual reassessment method to determine the safety and tolerability of 3K3A‐APC, a Recombinant Variant of Human Activated Protein C, in combination with tissue plasminogen activator, mechanical thrombectomy or both in moderate to severe acute ischemic stroke
This article is protected by copyright. All rights reserved. (Source: Annals of Neurology)
Source: Annals of Neurology - November 18, 2018 Category: Neurology Authors: Patrick Lyden, Kent E. Pryor, Christopher S. Coffey, Merit Cudkowicz, Robin Conwit, Ashutosh Jadhav, Robert N. Sawyer, Jan Claassen, Opeolu Adeoye, Shlee Song, Peter Hannon, Natalia S. Rost, Archana Hinduja, Michel Torbey, Jin ‐Moo Lee, C Tags: Research Article Source Type: research

Homozygous splicing mutation in NUP133 causes Galloway –Mowat syndrome
This article is protected by copyright. All rights reserved (Source: Annals of Neurology)
Source: Annals of Neurology - November 14, 2018 Category: Neurology Authors: Atsushi Fujita, Hiroyasu Tsukaguchi, Eriko Koshimizu, Hitoshi Nakazato, Kyoko Itoh, Shohei Kuraoka, Yoshihiro Komohara, Masaaki Shiina, Shohei Nakamura, Mika Kitajima, Yoshinori Tsurusaki, Satoko Miyatake, Kazuhiro Ogata, Kazumoto Iijima, Na Tags: Research Article Source Type: research

Thalamic Strokes that Severely Impair Arousal Extend into the Brainstem
This article is protected by copyright. All rights reserved. (Source: Annals of Neurology)
Source: Annals of Neurology - November 12, 2018 Category: Neurology Authors: Joseph Hindman, Mark D. Bowren, Joel Bruss, Brad Wright, Joel C. Geerling, Aaron D. Boes Tags: Brief Communication Source Type: research

Attributable Risk of Alzheimer's Dementia Due to Age ‐Related Neuropathologies
This article is protected by copyright. All rights reserved. (Source: Annals of Neurology)
Source: Annals of Neurology - November 12, 2018 Category: Neurology Authors: Patricia A. Boyle, Lei Yu, Sue E. Leurgans, Robert S. Wilson, Ron Brookmeyer, Julie A. Schneider, David A. Bennett Tags: Research Article Source Type: research

Resolving the role of the paramedian thalamus in forebrain arousal mechanisms
Annals of Neurology, Volume 0, Issue ja, -Not available-. (Source: Annals of Neurology)
Source: Annals of Neurology - November 12, 2018 Category: Neurology Authors: Nicholas D. Schiff Tags: Invited Commentary Source Type: research

Clinical outcomes depending on acute blood pressure after cerebral hemorrhage
This article is protected by copyright. All rights reserved. (Source: Annals of Neurology)
Source: Annals of Neurology - November 12, 2018 Category: Neurology Authors: Kazunori Toyoda, Masatoshi Koga, Haruko Yamamoto, Lydia Foster, Yuko Y Palesch, Yongjun Wang, Nobuyuki Sakai, Takayuki Hara, Chung Y Hsu, Ryo Itabashi, Shoichiro Sato, Mayumi Fukuda, Thorsten Steiner, Byung ‐Woo Yoon, Daniel F Hanley, Adn Tags: Research Article Source Type: research

Biallelic COLGALT1 variants are associated with cerebral small vessel disease
This study aimed to identify novel genes that causeCOL4A1/COL4A2‐related disorders.MethodsWhole exome sequencing was performed in two families with suspectedCOL4A1/COL4A2‐related disorders. We validated the role ofCOLGALT1 variants by constructing a 3D structural model, evaluating ColGalT1 protein expression and ColGalT activity by western blotting and collagen galactosyltransferase assays, and performingin vitro RNA interference and rescue experiments.ResultsExome sequencing demonstrated biallelic variants inCOLGALT1 encoding collagen β (1‐O) galactosyltransferase 1, which was involved in the post‐translational m...
Source: Annals of Neurology - November 9, 2018 Category: Neurology Authors: Satoko Miyatake, Sacha Schneeberger, Norihisa Koyama, Kenji Yokochi, Kayo Ohmura, Masaaki Shiina, Harushi Mori, Eriko Koshimizu, Eri Imagawa, Yuri Uchiyama, Satomi Mitsuhashi, Martin C. Frith, Atsushi Fujita, Mai Satoh, Masataka Taguri, Yas Tags: Research Article Source Type: research

Brain ‐State Dependent Stimulation boosts functional recovery following stroke
This article is protected by copyright. All rights reserved. (Source: Annals of Neurology)
Source: Annals of Neurology - November 8, 2018 Category: Neurology Authors: Natalie Mrachacz ‐Kersting, Andrew J.T. Stevenson, Helle R. M. Jørgensen, Kåre Eg Severinsen, Susan Aliakbaryhosseinabadi, Ning Jiang, Dario Farina Tags: Research Article Source Type: research

Tocilizumab treatment for new ‐onset refractory status epilepticus
This article is protected by copyright. All rights reserved. (Source: Annals of Neurology)
Source: Annals of Neurology - November 8, 2018 Category: Neurology Authors: Jin ‐Sun Jun, Soon‐Tae Lee, Ryul Kim, Kon Chu, Sang Kun Lee Tags: Brief Communication Source Type: research